hypoaldosteronism
Table of Contents
hypoaldosteronism
introduction
clinical features
- hyperkalaemia - often called type IV renal tubular acidosis even though metabolic acidosis is not a significant feature
- urinary sodium wasting ⇒ volume depletion and hypotension
aetiology
hyporeninaemic hypoaldosteronism
- loss of renal cell mass > 70% (most commonly diabetic nephropathy)
- cyclosporine
aldosterone resistance
- drugs - aldosterone antagonists, trimethoprim, pentamidine
- pseudohypoaldosteronism
primary aldosterone deficiency (rare)
- primary adrenal insufficiency
- congenital adrenal hyperplasia
- aldosterone synthase deficiency
hypoaldosteronism.txt · Last modified: 2010/01/18 03:37 by 127.0.0.1