somatotropin
growth hormone / somatotropin
see also:
introduction
- a single chain polypeptide hormone secreted by somatotropic cells within the lateral wings of the anterior pituitary gland
- secretion is modulated by a wide variety of mechanisms including inhibition by somatostatin
- prolonged excessive secretion causes acromegaly
- in addition, excessive levels increases glycation stresses on the liver causing increased liver aging1)
- see also wikipedia
physiology
- its main actions are:
- anabolic
- increasing height in children and adolescents
- stimulates the growth of all internal organs excluding the brain
- increases muscle mass through sarcomere hypertrophy
- increases protein synthesis
- increases calcium retention, and strengthens and increases the mineralization of bone
- promotes energy availability:
- promotes lipolysis
- promotes gluconeogenesis in the liver and reduces hepatic glucose uptake
- stimulates the immune system
somatotropin.txt · Last modified: 2025/11/18 22:08 by gary1