<?xml version="1.0" encoding="UTF-8"?>
<!-- generator="FeedCreator 1.8" -->
<?xml-stylesheet href="https://ozemedicine.com/wiki/lib/exe/css.php?s=feed" type="text/css"?>
<rss version="2.0">
    <channel xmlns:g="http://base.google.com/ns/1.0">
        <title>OzEMedicine - Wiki for Australian Emergency Medicine Doctors</title>
        <description></description>
        <link>https://ozemedicine.com/wiki/</link>
        <lastBuildDate>Fri, 03 Apr 2026 23:22:27 +0000</lastBuildDate>
        <generator>FeedCreator 1.8</generator>
        <image>
            <url>https://ozemedicine.com/wiki/lib/tpl/dokuwiki/images/favicon.ico</url>
            <title>OzEMedicine - Wiki for Australian Emergency Medicine Doctors</title>
            <link>https://ozemedicine.com/wiki/</link>
        </image>
        <item>
            <title>abdominal aortic aneurysm (AAA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aaa</link>
            <description>abdominal aortic aneurysm (AAA)

see also:

	* vascular surgery
	* aortic dissection
	* thoracic aortic aneurysm
	*  abdominal pain in ED
	* atherosclerosis and primary prevention

Definitions:

	* do not confuse with aortic dissections which are sometimes called dissecting aneurysms &amp; are due to blood entering media &amp; splitting the aortic wall
	* may be either:
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Jul 2022 10:17:51 +0000</pubDate>
        </item>
        <item>
            <title>the patient with acute abdominal pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abdopain</link>
            <description>the patient with acute abdominal pain in the ED

see also:  general surgery;

	* NICS - pain medication for acute abdominal pain (pdf)
	* Western Health ED: pain medications instruction sheet (pdf)
	* Western Health ED: adult abdominal pain discharge instruction sheet (pdf)

Initial Mx of the haemodynamically unstable patient in ED with abdominal pain

	* examples include:
		* the patient with a rigid abdomen 
		* abdominal pain with referred shoulder tip pain - suggests free fluid in abdomen su…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 03 Mar 2024 13:50:50 +0000</pubDate>
        </item>
        <item>
            <title>central / periumbilical abdominal pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abdopain_central</link>
            <description>central / periumbilical abdominal pain in the ED

read this first:  abdominal pain in ED

periumbilical pain:

differential diagnosis:

	* abdominal aortic aneurysm
	* bowel conditions:
		* see bowel obstruction
			* small bowel obstruction (tends to be more painful early with more vomiting but more poorly localised than LBO)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 10 Aug 2018 14:47:00 +0000</pubDate>
        </item>
        <item>
            <title>epigastric pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abdopain_epig</link>
            <description>epigastric pain in the ED

read this first:  abdominal pain in ED

epigastric pain:

differential diagnosis:

	* abdominal aortic aneurysm
	* pancreatitis
	* peptic ulcer disease
	* gastritis
	* gastro-oesophageal reflux
	* acute myocardial infarction - esp. inferior AMI or diabetic patients, thus ECG in the elderly or diabetic
	* early appendicitis
	* diabetic ketoacidosis
	* biliary causes such as ascending cholangitis even in the cholecystectomy patient
	* other causes of Dyspepsia
	* aortic …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Oct 2019 04:39:18 +0000</pubDate>
        </item>
        <item>
            <title>Flank pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abdopain_flank</link>
            <description>Flank pain

see also:

	*  abdominal pain main page; 
	*  renal colic; 
	*  acute pyelonephritis; 
	*  abdominal aortic aneurysm (AAA);
	* The adult with back pain in the ED</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 Jan 2018 14:56:16 +0000</pubDate>
        </item>
        <item>
            <title>LIF pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abdopain_lif</link>
            <description>LIF pain in the ED

read this first:  abdominal pain in ED

Left iliac fossa pain:

differential diagnosis:

	* see as for RIF pain but not appendicitis
	* diverticulitis
		* usually age &gt; 50yrs
		* usually left sided pain, tenderness with altered bowel habits, tenesmus, low grade fever

	* epiploic appendagitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Apr 2018 07:39:43 +0000</pubDate>
        </item>
        <item>
            <title>Left upper quadrant abdominal pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abdopain_luq</link>
            <description>Left upper quadrant abdominal pain in the ED

	* read this first  abdominal pain in ED
	* see also:
		* LIF pain in the ED


Left upper quadrant pain:

differential diagnosis:

	* essentially as for epigastric pain but makes diagnoses of biliary disease or appendicitis much less likely
	* gastritis
	* peptic ulcer disease (PUD)
	* as for RUQ pain such as:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 06 Aug 2022 01:14:49 +0000</pubDate>
        </item>
        <item>
            <title>The child with abdominal pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abdopain_paed</link>
            <description>The child with abdominal pain

see also paediatric emergency medicine,  the adult patient with acute abdominal pain 

	* RCH guideline - abdominal pain
	* NSW NETS acute abdomen (pdf)

	* do not forget to consider an occult ingested button battery as a cause of gastro-like illness +/- haematemesis +/- melaena +/- fevers - if suspected do a CXR/AXR as unrecognised ingestions have caused a number of children to die in Australia recently</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 09 Jul 2015 12:38:01 +0000</pubDate>
        </item>
        <item>
            <title>RIF pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abdopain_rif</link>
            <description>RIF pain in the ED

read this first:  abdominal pain in ED

right iliac fossa pain:

differential diagnosis:

	* appendicitis
	* mesenteric adenitis
	* terminal ileitis (eg. Yersinia, Crohn's disease)
	* gynaecology causes:
		* ectopic pregnancy
		* pelvic inflammatory disease (PID)
		* the patient with an adnexal mass
		* ovarian cyst
		* endometriosis
		* chronic pelvic pain in women
		* rarely, pelvic vein (ovarian vein) thrombophlebitis:
			* usually post-partum or assoc. with gynae. surgery…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 May 2022 08:01:31 +0000</pubDate>
        </item>
        <item>
            <title>the patient with acute RUQ pain in ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abdopain_ruq</link>
            <description>the patient with acute RUQ pain in ED

read this first:  abdominal pain in ED

right upper quadrant pain:

differential diagnosis:

hepatobiliary:

	* see also: liver function tests (LFTs)
		* differential diagnosis:
			* biliary colic:
				* acute onset severe RUQ pain, usually going through to R scapula
				*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 31 Mar 2026 06:22:24 +0000</pubDate>
        </item>
        <item>
            <title>Suprapubic pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abdopain_suprapubic</link>
            <description>Suprapubic pain in the ED

read this first:  abdominal pain in ED

Suprapubic pain +/- radiation to back:

differential diagnosis:

	* abdominal aortic aneurysm (usually higher up than suprapubic though)
	* UTI / cystitis
	* acute urinary retention
	* ulcerative colitis
	* diverticulitis
	* gynae causes:
		* miscarriage / abruption
		* labour
		* dysmenorrhoea
		* endometriosis
		* imperforate hymen with retained menses (haematocolpos) in pre-menarchal pubertal females</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 05 Sep 2009 22:51:29 +0000</pubDate>
        </item>
        <item>
            <title>arterial and venous blood gases (ABGs/VBGs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abg</link>
            <description>arterial and venous blood gases (ABGs/VBGs)

see also:

	* clinical procedures in the ED
	* acid-base physiology
	* hypoxia
	* Life in the fast lane blog (2010) - sometimes it is dangerous to attempt to normalise ABG abnormalities, consider these examples

Introduction

	* arterial blood gas is a sampling of arterial blood taken from either a direct needle aspirate of an artery, or from an arterial line (“art line”)
	* it can provide valuable information on the acid-base status, ventilation stat…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 03 Aug 2024 06:23:33 +0000</pubDate>
        </item>
        <item>
            <title>Aboriginal Liaison Services</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aboriginal_liaison_services</link>
            <description>Aboriginal Liaison Services

Information about Aboriginal Hospital Liaison Officer service at Western Health

Staff can also refer Aboriginal patients to the follow organisations

1. Western Suburbs Indigenous Gathering Place

120-200 Rosamond Road
Maribyrnong VIC 3032
(03) 9318 7855
Open Weekdays 9am-5pm
www.gatheringplace.com.au

The Gathering Place offers medical, allied health, counselling and social support for a full list of services</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 08 Jun 2011 10:05:44 +0000</pubDate>
        </item>
        <item>
            <title>about the OzEMedicine wiki</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=about</link>
            <description>about the OzEMedicine wiki

	* return to home page
	* editors and authors of this wiki
	* Ozemedicine wikipedia stats

You can email the wiki administrator: gary at ozemedicine.com (change the at for @).

Currently, the wiki is early in its development with much initial material to be migrated, please be patient as it will take time for it to become comprehensive.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Nov 2009 19:44:53 +0000</pubDate>
        </item>
        <item>
            <title>about the OzEMedicine wiki</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=about1</link>
            <description>about the OzEMedicine wiki

	* return to home page
	* editors and authors of this wiki
	* Ozemedicine wikipedia stats

You can email the wiki administrator: gary at ozemedicine.com (change the at for @).

Currently, the wiki is early in its development with much initial material to be migrated, please be patient as it will take time for it to become comprehensive.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 20 Jul 2011 11:45:17 +0000</pubDate>
        </item>
        <item>
            <title>about the OzEMedicine wiki</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=about2</link>
            <description>about the OzEMedicine wiki

	* return to home page
	* editors and authors of this wiki
	* Ozemedicine wikipedia stats

You can email the wiki administrator: gary at ozemedicine.com (change the at for @).

Currently, the wiki is early in its development with much initial material to be migrated, please be patient as it will take time for it to become comprehensive.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 20 Jul 2011 11:48:55 +0000</pubDate>
        </item>
        <item>
            <title>skin abscesses</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abscess</link>
            <description>skin abscesses

see also:

	* labial abscess / Bartholins abscess
	* perirectal abscess
	* perianal abscess
	* hidradenitis suppurativa
	* incision and loop drainage of abscesses - instructions with video
	* perhaps a 7 day course of co-trimoxazole is useful after I&amp;D but are the rare risks worth it?

admission disposition

	* usually the operating unit if post-op
	* usually plastics if:
		*  superficial head or neck, hands, below knee
		*  in some hospitals, even gluteal and other superficial b…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 Dec 2017 00:45:37 +0000</pubDate>
        </item>
        <item>
            <title>left at own risk / absconding patient / missing patient / competence</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abscondingpt</link>
            <description>left at own risk / absconding patient / missing patient / competence

see also:

	* medico-legal issues in the ED
	* the ED waiting room
	* ACEM STATEMENT ON RESPONSIBILITY FOR CARE IN EMERGENCY DEPARTMENTS
	* WA Gov Mental Health missing person policy
	* MJA 2014: Potentially incapable patients objecting to treatment: doctors’ powers and duties
	* WH intranet only:
		* Western Health Refusal of Treatment / discharge at own risk (doc)
		* WH Mx of Section 351 patients in the ED
		* WH Missing Pa…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 31 Oct 2016 05:36:28 +0000</pubDate>
        </item>
        <item>
            <title>Child abuse</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=abuse_child</link>
            <description>Child abuse

	* RCH guideline - child abuse
	* Vic. DHS - Vulnerable Children - recognition and roles of professionals</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 08 Sep 2009 05:37:23 +0000</pubDate>
        </item>
        <item>
            <title>angiotensin I converting enzymes (ACE and ACE2)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ace</link>
            <description>angiotensin I converting enzymes (ACE and ACE2)

see also:

	* ACE inhibitors

Introduction

	* there are 2 main very differently acting ACE homologues:

ACE

	*  a zinc metallopeptidase which removes dipeptides from the C-terminus of a peptide and thus converts angiotensin I to the active vasocontrictor peptide</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 Mar 2020 11:31:56 +0000</pubDate>
        </item>
        <item>
            <title>ACE inhibitors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aceis</link>
            <description>ACE inhibitors

see also:

	* historical aspects and main differences between the ACEIs
	* angiotensin II receptor blockers (ARBs)
	* pharmacology main index
	* angiotensin
	* cardiology
	* Aust Presc Oct 2009 - renin inhibitors - mechanism of action
	* Aust Presc Oct 2009 - renin inhibitors - clinical implications

introduction:

	* ACE is an enzyme that converts:
		* inactive angiotensin I -&gt; vasoconstrictor peptide angiotensin II;
		* vasodilator peptide bradykinin -&gt; inactive fragments;

	* …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 30 Jul 2023 08:26:37 +0000</pubDate>
        </item>
        <item>
            <title>ACEM Fellowship exam resources</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=acem_fellowship_exam</link>
            <description>ACEM Fellowship exam resources

	* ACEM website

NB. content below is NOT affiliated or necessarily endorsed by the ACEM

general emergency medicine education resources

	* Global Medical Education Project
	* LITFL - ACEM Fellowship resources
	* tips on getting ready for passing the fellowship clinical exams

Study notes

	* James Hayes' VAQ sessions hosted by Simon Bolch (2008)
	* Simon Bolch's Fellowship exam notes (2008) - yes he did pass! congrats!

	* Simon Bolch's - approach to the Long Ca…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:58:15 +0000</pubDate>
        </item>
        <item>
            <title>ACEM Primary Exam resources</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=acem_primary_exam</link>
            <description>ACEM Primary Exam resources

	* ACEM website
	* ACEM Primary Exam syllabus (pdf)

NB. content below is NOT affiliated or necessarily endorsed by the ACEM

	* Western Health ED medical education and registrar training resource page
	* Austin and Northern Hospitals ED education website

Basic Sciences

	* Anatomy main index
	* pathology
	* physiology main index
	* pharmacology main index
	*  Anatomic Radiology
	* Clinical Pathology</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:55:58 +0000</pubDate>
        </item>
        <item>
            <title>achalasia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=achalasia</link>
            <description>achalasia

see also:

	* dysphagia

introduction

	* idiopathic achalasia is a rare condition characterized by a failure of the lower oesophageal sphincter to relax due to a loss of neurons in the myenteric plexus
	* it is appears it may be an auto-immune condition affecting neurons of the oesophagus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Aug 2019 15:15:47 +0000</pubDate>
        </item>
        <item>
            <title>Acetylcholinesterase inhibitors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=acheis</link>
            <description>Acetylcholinesterase inhibitors

see also:

	* acetylcholinesterase inhibitor poisoning - organophosphate insecticides, etc
	* pharmacology main index
	* parasympathetics

Acetylcholinesterase:

	* AChE is one of most efficient enzymes, can hydrolyse 3,105 ACh /min per molecule of AChE -&gt; turnover time of 150 microseconds:
		* AChE has binding site for quaternary gp of choline &amp; esteratic subsite, thus after cleavage of ACh, the choline-AChE conjugate releases choline &amp; the acetyl enzyme is rapi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Sep 2021 03:09:45 +0000</pubDate>
        </item>
        <item>
            <title>Achilles tendon injury</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=achilles_tendon</link>
            <description>Achilles tendon injury

see also:

	* orthopaedics in the ED
	* sports injuries

Achilles' tendon rupture

Epidemiology

	* incidence in the general population is 7 per 100,000
	* average age of patients is 30–40 years (due to the combination of degeneration and recreational sport) with a male-to-female ratio 4-5:1</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 Dec 2016 02:43:48 +0000</pubDate>
        </item>
        <item>
            <title>aciclovir and related antivirals (famciclovir, valaciclovir)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aciclovir</link>
            <description>aciclovir and related antivirals (famciclovir, valaciclovir)

see also:

	* viruses
	* Herpes simplex virus (HSV)
	* varicella-zoster virus (chickenpox/shingles)
	* herpes zoster (shingles)
	* meningitis

introduction

	* aciclovir is an antiviral agent which is active against Herpes simplex virus (HSV) types I and II and varicella-zoster virus (chickenpox/shingles)). 
	* also used as prophylaxis for cytomegalovirus (CMV) in patients with HIV / AIDS
	* in infected cells, HSV or VZV coded thymidi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 31 Mar 2026 07:09:07 +0000</pubDate>
        </item>
        <item>
            <title>acidosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=acidosis</link>
            <description>acidosis

see also:

	* acid-base physiology
	* metabolic acidosis
	* alkalosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Dec 2013 05:08:15 +0000</pubDate>
        </item>
        <item>
            <title>acid-base physiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=acid_base</link>
            <description>acid-base physiology

see also:

	* arterial and venous blood gases (ABGs/VBGs)

introduction

	* intracellular (IC) pH at 6-6.8 is lower than extracellular (EC) pH which is normally at 7.35-7.45, but is sensitive to changes in EC pH, and as cell processes are regulated by IC pH, the maintenance of EC pH is important.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Dec 2013 05:21:26 +0000</pubDate>
        </item>
        <item>
            <title>acne vulgaris</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=acne</link>
            <description>acne vulgaris

see also:

	* dermatology
	* acne rosacea
	* polycystic ovary syndrome (PCOS)
	* antibiotics

Introduction

	* acne is a chronic inflammatory skin disease of the sebaceous follicle. 
	* the hormonal factor, innate immunity and the microbiome play a crucial role in the onset of acne lesions. 
	* dysbiosis with an unbalanced presence of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 22 Aug 2024 15:02:31 +0000</pubDate>
        </item>
        <item>
            <title>common acronyms</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=acronyms</link>
            <description>common acronyms

see also:

	* welcome to the OzEMedicine Wiki
  acronym    meanings AKI  acute kidney impairment  AO  assessment order (mental health)  ARF  acute renal failure  AV  Ambulance Victoria /atrio-ventricular  Ax  assessment  BIBA  Brought in by ambulance  CAP  chest, abdo, pelvis /community acquired pneumonia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 12 Jan 2025 00:42:01 +0000</pubDate>
        </item>
        <item>
            <title>adrenocorticotropic hormone (ACTH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=acth</link>
            <description>adrenocorticotropic hormone (ACTH)

see also:

	* hormones
	* angiotensin
	* corticosteroids

introduction

	* ACTH (aka corticotropin) is a polypeptide hormone secreted by the anterior pituitary gland
	* its main actions are to increase synthesis and secretion of corticosteroids from the zona fasciculata of the adrenal cortex (via MC2R ACTH receptor) as part of the biological stress response</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 11 May 2014 11:48:50 +0000</pubDate>
        </item>
        <item>
            <title>actuarial science - predicting life expectancy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=actuary</link>
            <description>actuarial science - predicting life expectancy

see also:

	* welcome to the OzEMedicine Wiki
	* Ubble's 2015 risk calculator for death within next 5 years - uses just 11-13 questions
	* wikipedia - longevity
	* wikipedia -actuarial science
	* wikipedia - life tables - probability of death before next birthday

definitions

	* life expectancy (ex) = avg. number years of life remaining for a person at age x
	* life expectancy at birth (e0) = avg. number years of life from birth</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 27 Sep 2015 03:03:25 +0000</pubDate>
        </item>
        <item>
            <title>acute bronchitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=acute_bronchitis</link>
            <description>acute bronchitis

see also:

	* acute cough in the adult
	* chronic bronchitis
	* community acquired pneumonia (CAP) in adults

introduction

	* acute bronchitis is a common cause of cough, and it is generally a diagnosis of exclusion of more serious conditions such as community acquired pneumonia (CAP) in adults
	* &gt;85% are viral and there is limited evidence that antibiotics are of use in healthy individuals</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 10 Mar 2017 02:26:46 +0000</pubDate>
        </item>
        <item>
            <title>acute dyspnoea / shortness of breath (SOB)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=acute_dyspnoea</link>
            <description>acute dyspnoea / shortness of breath (SOB)

see also:

	* respiratory medicine

Introduction

	*  A 2017-published international trial (Australia, NZ, Singapore, Malaysia,Hong Kong) of 3,044 people found: Patients with dyspnoea made up 5.2% of ED presentations, 11.4% of ward admissions, and 19.9% of intensive care unit (ICU) admissions. The most common diagnoses were lower respiratory tract infection (20.2%), heart failure (14.9%), chronic obstructive pulmonary disease (13.6%), and asthma (12.7%…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 09 Oct 2019 07:46:01 +0000</pubDate>
        </item>
        <item>
            <title>adaptive immunity</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=adaptive_immunity</link>
            <description>adaptive immunity

see also:

	* innate immunity
	* immunology
	* autoimmune disease

Introduction

	* adaptive immunity refers to the ability to specifically target pathogens based upon past exposure to that pathogen
	* in contrast, innate immunity is a relatively non-specific immunity system although pentraxin 3 (PTX3) does play a similar role as antibodies but they are not adaptive to new pathogens</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 07 Jan 2026 22:57:43 +0000</pubDate>
        </item>
        <item>
            <title>addiction medicine (alcohol and other substance use)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=addiction_medicine</link>
            <description>addiction medicine (alcohol and other substance use)

see also:

	* addiction medicine - drug and alcohol service providers in Australia
	* drug dependency
	* ethanol/alcohol dependence
	* opiate and opioid dependence
	* acute pain Mx in drug dependent patients
	* analgesics index 
	* opiates and opioids
	*  opiate antagonists eg naloxone (Narcan), buprenorphine, naltrexone 
	* metamphetamine / meth / ice
	* National Drug and Alcohol Research Centre (NDARC) - drug trends bulletin

Western Health…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:45:40 +0000</pubDate>
        </item>
        <item>
            <title>adenosine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=adenosine</link>
            <description>adenosine

see also:

	* pharmacology main index
	* autacoids
	* methylxanthines - adenosine receptor antagonists

Introduction:

	* adenosine is a naturally occurring endogenous nucleoside 
	* adenosine is rapidly taken up by RBC's &amp; endothelial cells such that almost completely eliminated from circulation after 1st pass -&gt; plasma T1/2 &lt; 10secs;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Feb 2009 04:49:34 +0000</pubDate>
        </item>
        <item>
            <title>adenovirus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=adenovirus</link>
            <description>adenovirus

see also:

	* viruses
	* &lt;https://www.news-medical.net/news/20221109/What-is-the-role-of-adenoviruses-in-human-health.aspx&gt;

introduction

	* human adenoviruses are a group of common viruses with a wide range of clinical manifestations
	* it is also an important pathogen in immunocompromised patients such as post-transplant
	* there are 51 serotypes currently recognized, classified into 6 species (A-F)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 09 Nov 2022 14:27:47 +0000</pubDate>
        </item>
        <item>
            <title>attention deficit hyperactivity disorder (ADHD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=adhd</link>
            <description>attention deficit hyperactivity disorder (ADHD)

see also:

	* autism spectrum disorder (ASD)
	* Asperger's syndrome
	* DSM V proposed changes to ADHD criteria
	* NSW Health ADHD faqs

introduction

	* AD/HD consists of a pattern of behavior that is present in multiple settings where it gives rise to social, educational or work performance difficulties
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Dec 2025 22:14:14 +0000</pubDate>
        </item>
        <item>
            <title>adipokines and adipose-derived hormones</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=adipokines</link>
            <description>adipokines and adipose-derived hormones

see also:

	* obesity
	* diabetes mellitus
	* cytokines

introduction

	* it is becoming increasingly evident that adipose tissue has major endocrine roles
	* adipokines is a term being used to categorise proteins released from adipose tissue, however, as they do not generally act upon the immune system, they are not grouped under</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Mar 2026 02:03:03 +0000</pubDate>
        </item>
        <item>
            <title>administrative aspects of Emergency Medicine in Australia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=administration</link>
            <description>administrative aspects of Emergency Medicine in Australia

see also:

	* main Wiki index; 
		* Emergency Department Information Systems (EDIS);
		* Healthcare providers
		* medico-legal issues in the ED
		* common emergency department patient presentations

Some useful links

	* Australiasian College for Emergency Medicine (ACEM)
		* ACEM MOPS web page for ACEM physician CME

	* Australiasian Society for Emergency Medicine (ASEM)
	* MBS schedule
	* PBS - approved medications search
	* Vic DHS Ma…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 30 Aug 2020 09:40:12 +0000</pubDate>
        </item>
        <item>
            <title>the patient with an adnexal mass</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=adnexal_mass</link>
            <description>the patient with an adnexal mass

see also:

	* gynaecology
	* the patient with acute abdominal pain in the ED
	* ovarian tumours

introduction

	* an adnexal mass that is solid, complex, or larger than 8cm in any age group should be treated as possibly malignant (and if larger than 8cm is at risk of complication and should probably be removed anyway).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Oct 2009 22:43:40 +0000</pubDate>
        </item>
        <item>
            <title>adrenaline / epinephrine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=adrenaline</link>
            <description>adrenaline / epinephrine

see also:

	* pharmacology main index
	* sympathomimetics
	* alpha adrenergic agonists
	* noradrenaline / norepinephrine
	* inotropes
	* vasopressors
	*  Paediatric Resuscitation Drugs
	* Western Health Adrenaline Administration Procedure (intranet only)
	* Aust. Prescriber 2012 - Safe use of adrenaline autoinjectors

also called epinephrine in the USA.

presentation

	* ampoules for parenteral use:
		* 1:1000 = 1mg in 1ml
		* 1:10,000 = 1mg in 10ml (also available as a…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 07 Jan 2026 22:51:55 +0000</pubDate>
        </item>
        <item>
            <title>adrenergic storm</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=adrenergic_storm</link>
            <description>adrenergic storm

see also:

	* sympathomimetics

Introduction

	* an adrenergic storm  is a potentially life threatening sudden increase in serum levels of the catecholamines, mainly, epinephrine and norepinephrine
	* see also sudden transient surges in BP 

Aetiology

	* cocaine overdose
	* metamphetamine / meth / ice overdose
	* septic shock
	* monoamine oxidase inhibitors (MAOIs)
	* phaeochromocytoma</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Jun 2025 08:13:35 +0000</pubDate>
        </item>
        <item>
            <title>aerosols</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aerosols</link>
            <description>aerosols

see also:

	* aerosol generating procedures (AGPs)
	* pandemics - influenza, coronavirus, Ebola
	* &lt;https://first10em.com/aerosols-droplets-and-airborne-spread/&gt;

Introduction

	* most respiratory tract viral infections are spread by droplets or aerosols from coughing or sneezing 
	* smaller sized droplets less than 5 microns in diameter can become aerosols and hang in the air and circulate through the room or into other rooms for a number of hours vastly increasing the range of infect…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 19 Sep 2020 00:52:31 +0000</pubDate>
        </item>
        <item>
            <title>aged care index</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=agedcare</link>
            <description>aged care index

	* geriatrics
	* home care for the elderly
	* residential aged care - hostel and nursing home care
	* end of life care
	* delirium
	* fracture neck of femur (#NOF)
	* Vic. DHS - aged care in the acute hospital setting - practice guidelines, etc
		* Vic. DHS - Mx of delirium in older patients (pdf)
		* Vic. DHS - Stroke care pathway (pdf)
		* Vic. DHS - Age-friendly principles - managing older people in hospital environments (pdf)
		* Vic. DHS - a guide for assessing older patien…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 17 Jun 2019 14:54:33 +0000</pubDate>
        </item>
        <item>
            <title>home care for the elderly</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aged_home_care</link>
            <description>home care for the elderly

see also:

	* aged care index
	* residential aged care - hostel and nursing home care
	* Aged Care information sheets

introduction

	* there is a Community Care Common Standards Guide to ensure all people receive an acceptable standard of service
	* the prime aim of home care programs is to enable the frail elderly and disabled to remain in their homes longer, maintain health and remain safe while postponing the need for residential care</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 26 Apr 2012 09:42:28 +0000</pubDate>
        </item>
        <item>
            <title>residential aged care - hostel and nursing home care</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aged_residential_care</link>
            <description>residential aged care - hostel and nursing home care

see also:

	* aged care index
	* home care for the elderly

introduction

	* nursing homes generally have both high and low level care accommodation
	* hostels are low level care accommodation

getting into residential care

	* 5 steps are required:
		* assessing eligibility via an Aged Care Assessment Team (ACAT) assessment (referred by local doctor or hospital) who can:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:38:25 +0000</pubDate>
        </item>
        <item>
            <title>ageing</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aging</link>
            <description>ageing

see also:

	* androgen deficiency
	* geriatrics
	* longevity and immortality
	* wikipedia

Introduction

	* the biologic factors causing mammalian aging process is still poorly understood
	* aging is one of the most common risk factors for human disease

why do we age?

	* the rate of ageing varies substantially across different species, and this is mainly genetically based and the biological mechanisms which regulate lifespan evolved several hundred million years ago</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 04:10:18 +0000</pubDate>
        </item>
        <item>
            <title>aerosol generating procedures (AGPs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=agps</link>
            <description>aerosol generating procedures (AGPs)

see also:

	* aerosols
	* viruses
	* pandemics - influenza, coronavirus, Ebola
	* &lt;https://first10em.com/aerosol-generating-procedures/&gt;
	* &lt;https://dontforgetthebubbles.com/aerosol-generating-procedures/&gt;
	* PLoS One. 2012; Aerosol Generating Procedures and Risk of Transmission of Acute Respiratory Infections to Healthcare Workers: A Systematic Review (SARS)
	* Scientific Reports volume 8, Article number: 198 (2018)Exhaled air dispersion during bag-mask ven…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 25 Oct 2020 02:13:00 +0000</pubDate>
        </item>
        <item>
            <title>agranulocytosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=agranulocytosis</link>
            <description>agranulocytosis

see neutropenia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 27 Jan 2020 04:28:13 +0000</pubDate>
        </item>
        <item>
            <title>AIDS</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aids</link>
            <description>AIDS

see also:

	* HIV / AIDS

introduction

	* AIDS is diagnosed when the immune system of a person infected with HIV becomes severely compromised (measured by CD4 cell count) and⁄or the person becomes ill with an opportunistic infection or illness. 
	* without treatment, AIDS usually develops 8 to 10 years after initial HIV infection;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 19 Sep 2020 03:15:50 +0000</pubDate>
        </item>
        <item>
            <title>acute intermittent porphyria (AIP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aip</link>
            <description>acute intermittent porphyria (AIP)

see also:

	* porphyrias

introduction

	* an autosomal dominant type of porphyria affecting porphobilinogen-deaminase
	* acute attacks may cause:
		* psychiatric or CNS symptoms (eg. hysteria, depression, seizures, cortical blindness, coma)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Apr 2014 06:48:29 +0000</pubDate>
        </item>
        <item>
            <title>Acute upper airway obstruction</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=airway_obst_paed</link>
            <description>Acute upper airway obstruction

see also croup, paediatric emergency medicine, anaesthetics

	* RCH guideline - acute upper airway obstruction</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 05:15:28 +0000</pubDate>
        </item>
        <item>
            <title>air embolism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=air_embolism</link>
            <description>air embolism

see also:

	* post-partum / puerperial complications
	* the blood donor who collapses

Introduction

	* air in the circulatory system is a rare cause of death
	* minor cases of venous embolism are common and do not usually cause problems
	* air entering the venous system becomes trapped in the right ventricle resulting in low cardiac output and embolising to the pulmonary circulation causing obstruction to pulmonary blood flow causing V/Q mismatch, while inflammatory responses can …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Aug 2019 01:04:30 +0000</pubDate>
        </item>
        <item>
            <title>air pollution and health risks</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=air_pollution</link>
            <description>air pollution and health risks

see also:

	* respiratory medicine
	* foods that may be toxic or bad for you
	* risk and the perception of risk
	* exposome and health

	* it is not only air pollutants that are bad for you, dry air (eg. prolonged air conditioning) or prolonged exposure to cold air is also bad for you (WHO recommends minimum household temperatures of 18degC)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Feb 2026 21:33:44 +0000</pubDate>
        </item>
        <item>
            <title>aldosterone</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aldosterone</link>
            <description>aldosterone

see also:

	* aldosterone antagonists
	* hypoaldosteronism
	* hyperaldosteronism
	* hypertension
	* endocrinology
	* physiology main index

introduction

	* A mineralocorticoid secreted from adrenal cortex &amp; rapidly conjugated by liver (and kidney) so T1/2 = 20 minutes

secretion:

stimulated by:

	* ACTH (via cAMP &amp; protein kinase A);
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Jun 2023 10:16:48 +0000</pubDate>
        </item>
        <item>
            <title>aldosterone antagonists (mineralocorticoid receptor antagonists (MRAs) )</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aldosterone_antags</link>
            <description>aldosterone antagonists (mineralocorticoid receptor antagonists (MRAs) )

see also:

	* diuretics
	* aldosterone
	* hypoaldosteronism

Introduction

	* Competitive antagonists of aldosterone (mineralocorticoids) acting on the receptor which is a soluble cytoplasmic protein thereby inhib. the synthesis of physiologically active transport proteins:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 03:20:35 +0000</pubDate>
        </item>
        <item>
            <title>alkalosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=alkalosis</link>
            <description>alkalosis

see also:

	* acid-base physiology
	* acidosis
	* metabolic alkalosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Dec 2013 05:08:50 +0000</pubDate>
        </item>
        <item>
            <title>allergens</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=allergens</link>
            <description>allergens

see also:

	* allergy and hypersensitivity reactions
	* anaphylaxis
	* asthma

introduction

	* allergen exposure in sensitive individuals may cause allergic rhinitis, conjunctivitis, pruritis and asthma
	* rarely, it may cause anaphylaxis
	* the main rule is to avoid allergens where possible, or at least minimise the exposure load</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 13 Mar 2026 05:18:48 +0000</pubDate>
        </item>
        <item>
            <title>allergy and hypersensitivity reactions</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=allergy</link>
            <description>allergy and hypersensitivity reactions

see also:

	* immunology
	* histamine physiology, receptors and antihistamines
	* antihistamines (H1)
	* anaphylaxis
	* allergens
	* illness after eating seafood
	* Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN)
	* urticaria
	* hereditary angioedema (HAE)
	* radiologic contrast media precautions and adverse reactions
	* eosinophilia
	* allergic rhinitis
	* asthma
	* tick-induced mammalian red meat allergy (MMA) / alpha-gal syndrome
	* …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 09 Feb 2026 21:30:06 +0000</pubDate>
        </item>
        <item>
            <title>allodynia - painful touch when there should not be pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=allodynia</link>
            <description>allodynia - painful touch when there should not be pain

see also:

	* hyperalgesia - increased sensitivity to painful stimuli
	* neurology

Introduction

	* allodynia is pain felt with non-painful stimuli
		*  affects 15-50% of people with neuropathic pain

	* hyperalgesia - increased sensitivity to painful stimuli is an increased sensitivity to painful stimuli 

Types of allodynia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 22 Sep 2024 06:11:47 +0000</pubDate>
        </item>
        <item>
            <title>allopurinol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=allopurinol</link>
            <description>allopurinol

see also gout

Summary

	* Originally synthesised as candidate for antineoplastic activity which it lacked but proved to be a substrate for &amp; inhibitor of xanthine oxidase thus reducing uric acid production although it also inhibits uric acid renal excretion;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 30 Oct 2025 06:20:57 +0000</pubDate>
        </item>
        <item>
            <title>alopecia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=alopecia</link>
            <description>alopecia

see also:

	* androgenetic alopecia
	* dermatology
	* scalp and hair conditions

Introduction

	* scalp hair biology
		* everyone is born with a fixed number of hair follicles on the scalp that produce hairs throughout life.
		* unlike other areas of the body, hairs on the scalp to grow in tufts of 3–4</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Feb 2026 10:15:24 +0000</pubDate>
        </item>
        <item>
            <title>androgenetic alopecia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=alopecia_androgenetic</link>
            <description>androgenetic alopecia

see also:

	* androgens
	* alopecia
	* polycystic ovary syndrome (PCOS)

Introduction

	* androgenetic alopecia is male pattern balding which appears to have a multi-factorial causation although genetic polymorphisms appear to have a key role which may influence the hair follicle cycle and the drivers of this cycle such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 13 Jul 2019 16:46:29 +0000</pubDate>
        </item>
        <item>
            <title>alpha adrenergic agonists</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=alphaagonists</link>
            <description>alpha adrenergic agonists

see also:

	* sympathomimetics
	* vasopressors
	* inotropes

	* excessive systemic dosing may cause hypertensive crisis which may be fatal, and attempts to treat such alpha agonist crises with beta adrenergic blockers or calcium channel blockers may cause acute pulmonary oedema (APO) and thus these agents are contra-indicated!!

introduction</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Jul 2019 07:33:58 +0000</pubDate>
        </item>
        <item>
            <title>alpha adrenergic blockers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=alphablockers</link>
            <description>alpha adrenergic blockers

see also:

	* pharmacology main index
	* cardiology
	* beta blockers
	* sympathomimetics
	* benign prostatic hyperplasia (BPH)

introduction

	* alpha blockers prevent the action of sympathomimetic agents such as adrenaline on the alpha adrenergic receptors

potential pharmacologic effects of alpha-blockers

	* postural hypotension and dizziness +/- reflex tachycardia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 Jun 2017 11:40:21 +0000</pubDate>
        </item>
        <item>
            <title>Apparent Life-Threatening Events in Children (ALTE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=alte</link>
            <description>Apparent Life-Threatening Events in Children (ALTE)

see also:

	* SIDS
	* RCH guideline - ALTE</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 03 Aug 2011 07:12:47 +0000</pubDate>
        </item>
        <item>
            <title>alteplase</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=alteplase</link>
            <description>alteplase

see also:

	* thrombolytics

Introduction

	* atleplase is r-TPA and an intravenous thrombolytic agent used to dissolve blood clots within the vasculature

pharmacology:

	* 1st clinical use of a tPA reported in 1984
	* tPA is a naturally occurring serine protease protein produced commercially via recombinant DNA techniques</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 20 Nov 2019 05:25:29 +0000</pubDate>
        </item>
        <item>
            <title>aluminium</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aluminium</link>
            <description>aluminium

see also:

	* foods that may be toxic or bad for you

Introduction

	* aluminium is the most common metal in the Earth’s crust and it finds its way into the plants via the soil and high levels of ingestion may have adverse effects 
	* aluminum exposure occurs through some plant foods, food packaging, medications, water, and industrial sources.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Mar 2026 23:45:37 +0000</pubDate>
        </item>
        <item>
            <title>amenorrhoea</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=amenorrhoea</link>
            <description>amenorrhoea

see also:

	* menorrhagia / PV bleeding
	* gynaecology
	* infertility
	* follicle stimulating hormone (FSH)
	* luteinizing hormone (LH)

introduction

	* amenorrhea is not usually a common ED presentation as most are managed by general practitioners but nevertheless it may need consideration in the ED setting, usually in terms of whether a patient is pregnant or not, or in the Mx of episodes of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:59:14 +0000</pubDate>
        </item>
        <item>
            <title>acute myocardial infarction (AMI/STEMI/NSTEMI)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ami</link>
            <description>acute myocardial infarction (AMI/STEMI/NSTEMI)

see also:

	* cardiology
	* Mx of chest pain in ED
	* thrombolytics
	* Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA)
	* atherosclerosis and primary prevention
	* web resources:
		* AMI probability calculator (Goldman)
		* Probability of bleeding from thrombolysis Rx in AMI - scoring tool
		* EMedicine
		* sandnsurf's blog Mx of STEMI - with references
		* Aust Presc 2007 - Antiplatelet therapy after coronary occlusion
		* Aus…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 28 Dec 2025 22:52:51 +0000</pubDate>
        </item>
        <item>
            <title>aminoglycoside antibiotics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aminoglycosides</link>
            <description>aminoglycoside antibiotics

see also;

	* antibiotics

introduction

	* bactericidal group originally obtained from Streptomyces species
		* ototoxic &amp; nephrotoxic if high dose or prolonged use
		* active mainly against enteric Gram -ve bacteria
		* uses: septicaemia, endocarditis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 01 Dec 2011 06:19:33 +0000</pubDate>
        </item>
        <item>
            <title>aminophylline</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aminophylline</link>
            <description>aminophylline

see also:

	* methylxanthines
	* theophylline and methylxanthine poisonings and overdoses
	* asthma
	* paediatric asthma

introduction

	* aminophylline is a one of the methylxanthines groupd of medications along with theophylline and caffeine.
	* 400 mg theophylline is equivalent to 500 mg aminophylline
	* ampoules: 250 mg /10 mL
	* therapeutic serum levels: 55-110 umol/L (10-20 mcg/mL)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2009 08:40:35 +0000</pubDate>
        </item>
        <item>
            <title>amiodarone</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=amiodarone</link>
            <description>amiodarone

see also:

	* pharmacology main index
	* anti-arrhythmic agents
	* WH policy - amiodarone infusion (docx) - intranet only

introduction:

	* type 3 V-W anti-arrhythmic agent which also has some noncompetitive alpha adrenergic blockade as well;
	* commonly used in Rx of many arrhythmias including VT, AF

	* not compatible with NSaline or heparin

actions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Dec 2015 03:19:19 +0000</pubDate>
        </item>
        <item>
            <title>amlodipine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=amlodipine</link>
            <description>amlodipine

see also:

	* calcium channel blockers
	* calcium channel blocker overdose

introduction

	* a dihydropyridine calcium blocking agent 
	* act mainly on arteriolar smooth muscle to reduce peripheral vascular resistance and thus reduces blood pressure
	* often formulated with other agents such as statins, ACE inhibitors

indications

	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Dec 2015 04:29:09 +0000</pubDate>
        </item>
        <item>
            <title>serum ammonia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ammonia</link>
            <description>serum ammonia

see also:

	* hepatic encephalopathy

Introduction

	* ammonia is biosynthesised through normal amino acid metabolism and is important for normal animal acid/base balance but is toxic in high concentrations
	* ammonia load is increased with high protein intake or GIT bleeding</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 07:09:15 +0000</pubDate>
        </item>
        <item>
            <title>amoebiasis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=amoebiasis</link>
            <description>amoebiasis

see also:

	* parasites
	* the febrile returned traveller

introduction

	* infection caused by the amoeba Entamoeba histolytica
	* usually transmitted by the fecal-oral route
	* amoebiasis is estimated to cause 70,000 deaths per year world wide
	* it is often endemic in regions of the world with limited modern sanitation systems, including Mexico, Central America, western South America, South Asia, and western and southern Africa.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 08 Jul 2024 05:27:49 +0000</pubDate>
        </item>
        <item>
            <title>amphetamines and related psychostimulant substances</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=amphetamines</link>
            <description>amphetamines and related psychostimulant substances

see also:

	* sympathomimetics; 
	* drug dependency; 
	* Mx of toxicity from amphetamines and related substances
	* intravenous drug users (IVDU) or injection drug use (IDU)

history

	* Chinese use stimulant ephedra (ma huang) containing the alkaloids ephedrine &amp; pseudoephedrine for over 5000yrs to Rx asthma &amp; URTI.
	* amphetamine 1st synthesised in Germany in 1887 but not used clinically until 1920's following reduced availability of ephedri…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 22 Dec 2023 10:10:03 +0000</pubDate>
        </item>
        <item>
            <title>amyloidosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=amyloidosis</link>
            <description>amyloidosis

see also:

	* wikipedia
	* multiple myeloma
	* monoclonal gammopathy of uncertain significance (MGUS)

introduction

	* a variety of conditions in which amyloid proteins are deposited in tissues.
	* a protein is described as being amyloid if, due to an alteration in its secondary structure, it takes on a particular aggregated insoluble form similar to the beta-pleated sheet.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Aug 2024 06:19:12 +0000</pubDate>
        </item>
        <item>
            <title>anti-nuclear antibodies (ANA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ana</link>
            <description>anti-nuclear antibodies (ANA)

see also:

	* the swollen joint and its diagnostic workup
	* systemic lupus erythematosus (SLE)

introduction

	* Antinuclear antibodies (ANAs) are diverse, and some have specific disease associations. Many of the autoimmune diseases are associated with a positive ANA test. A positive ANA is 1 of the 11 criteria used in the diagnosis SLE.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Jun 2025 01:20:34 +0000</pubDate>
        </item>
        <item>
            <title>anabolic steroids</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anabolic_steroids</link>
            <description>anabolic steroids

see also:

	* androgens, testosterone and androgenic effects

Introduction

	* synthetic steroids with high anabolic effect : androgen effect ratio (testosterone is 1:1)
	* most are 17-alkyl-substituted steroids &amp; thus risk hepatic dysfunction

examples:

	* ethylestrenol (4-8:1)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 Dec 2025 22:02:07 +0000</pubDate>
        </item>
        <item>
            <title>anaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anaemia</link>
            <description>anaemia

see also:

	* iron deficiency anaemia
	* haemolytic anaemia
	* thalassemia
	* blood product transfusions
	* haematology
	* RCH guideline - anaemia in children</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 13 Mar 2021 23:42:28 +0000</pubDate>
        </item>
        <item>
            <title>haemolytic anaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anaemia_haemolytic</link>
            <description>haemolytic anaemia

see also:

	* anaemia

introduction

	* premature destruction of RBC's resulting in anaemia, haemoglobinuria (if occurs when the amount of free hemoglobin released during hemolysis exceeds available haptoglobin), release of LDH, raised indirect bilirubin and urobilinogen and</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 May 2018 04:08:59 +0000</pubDate>
        </item>
        <item>
            <title>iron deficiency anaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anaemia_irondef</link>
            <description>iron deficiency anaemia

see also:

	* anaemia
	* ferritin
	* MJA Guidelines - Diagnosis and management of iron deficiency anaemia: a clinical update
	* GP referral of community based patients requiring transfusion at Western Health
	* Nat. Blood Authority Australia March 2016: Iron product choice and dose calculation for adults (pdf)

introduction

	* always attempt to determine the cause of iron deficiency to ensure underlying malignancy or PU disease is excluded.
	* recommended daily iron int…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Jun 2025 07:47:55 +0000</pubDate>
        </item>
        <item>
            <title>dental anaesthesia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anaesthesia_dental</link>
            <description>dental anaesthesia

see also:

	* local anaesthetic agents
	* dental injuries

maxillary teeth

maxillary infiltration

	* maxillary infiltrations are used to anaesthetise any maxillary teeth
	* retract lip
	* inject 2ml of lignocaine with adrenaline using 25G needle at the deepest part of the sulcus directly above the tooth involved with the needle penetrating 2mm deep into the tissues</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 22 Feb 2009 06:35:06 +0000</pubDate>
        </item>
        <item>
            <title>anaesthetics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anaesthetics</link>
            <description>anaesthetics

see also:

	* rapid sequence induction (RSI) for emergency intubation
	* history of anaesthesia
	* medical gases
	* induction agents
		* ketamine
		* propofol
		* thiopentone

	* neuro-muscular blockers
		* suxamethonium
		* vecuronium

	* pain, analgesia and analgesics
		* RCH guideline - paediatric procedural sedation guideline
		* RCH guideline - procedural pain management
		* RCH guideline - paediatric analgesia and sedation
		* RCH guideline - nitrous oxide

	* sedatives, hypn…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Mar 2009 03:21:08 +0000</pubDate>
        </item>
        <item>
            <title>general anaesthesia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anaestheticsgeneral</link>
            <description>general anaesthesia

see also:

	* anaesthetics
	* history of anaesthesia
	* induction agents for anaesthesia
	* neuro-muscular blockers

traditional stages of anaesthesia

	* stage of analgesia
		* no amnesia until late in stage.

	* stage of excitement
		* delirium, excited, amnesic, irregular respiration, vomiting, incontinence.

	* stage of surgical anaesthesia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Jun 2025 23:07:47 +0000</pubDate>
        </item>
        <item>
            <title>local anaesthetic agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anaestheticslocal</link>
            <description>local anaesthetic agents

see also:

	* local anaesthesia nerve blocks
	* anaesthetics
	* dental anaesthesia
	* history of anaesthesia
	* lignocaine
	* Co-Phenylcaine Forte Spray

	* remember 1% solution = 10mg/ml
	* thus for lignocaine, max. s/c dose without adrenaline of 4.5mg/kg for a 20kg child = 9mls (4.5 x 20 / 10)
	* toxicity may be managed by use of lipid emulsion infusion</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 01 Aug 2013 04:12:29 +0000</pubDate>
        </item>
        <item>
            <title>pain, analgesia and analgesics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=analgesics</link>
            <description>pain, analgesia and analgesics

see also anaesthetics

	* paracetamol (acetaminophen)
	* non-steroidal anti-inflammatory drugs (NSAIDs)
	* opiates and opioids (eg. morphine)
	* methoxyflurane
	* neuropathic pain and its Mx
	* acute pain Mx in drug dependent patients
	* drug dependency
	* Australian Prescriber 2011 - analgesics in pregnancy and breastfeeding (pdf)
	* Use of tramadol in the ED
	* RCH guideline - paediatric procedural sedation guideline
	* RCH guideline - paediatric procedural pain…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 19 Jul 2017 22:39:17 +0000</pubDate>
        </item>
        <item>
            <title>anal fissure</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anal_fissure</link>
            <description>anal fissure

see also:

	* perianal abscess
	* perirectal abscess
	* haemorrhoids
	* ano-rectal pain
	* anal fistula / fistula-in-ano
	* proctitis
	* PR_exam
	* Aust Prescr. 2016 Anal fissure

Introduction

	* anal fissure is a common acutely painful condition of the anus
	* it is usually due to “microtrauma” but may be secondary to other illnesses
	* most are benign and resolve over a week to 6 weeks but some may become chronic and require surgical intervention</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 Jul 2020 03:07:19 +0000</pubDate>
        </item>
        <item>
            <title>anal fistula / fistula-in-ano</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anal_fistula</link>
            <description>anal fistula / fistula-in-ano

see also:

	* ano-rectal pain
	* perirectal abscess
	* skin abscesses
	* labial abscess / Bartholins abscess
	* inflammatory bowel disease (IBD)

Introduction

	* a fistula with its internal opening in the anal canal and its external opening in the skin near the anus
	* they originate from the anal glands which are located between the internal and external anal sphincter, and which drain into the anal canal</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 23 Sep 2018 23:11:06 +0000</pubDate>
        </item>
        <item>
            <title>anaphylaxis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anaphylaxis</link>
            <description>anaphylaxis

see also

	* adrenaline / epinephrine
	* angioedema
	* allergy and hypersensitivity reactions
	* radiologic contrast media precautions and adverse reactions
	* scombroid histamine food poisoning due to spoiled fish
	* Aust. Prescriber 2012 - Safe use of adrenaline autoinjectors
	* Allergy.org.au - action plan for anaphylaxis
	* in Victoria, all anaphylaxis events are mandatory reporting to DHHS - see Anaphylaxis notifications
	* in Victoria, allergy events to drugs or blood products…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:47:04 +0000</pubDate>
        </item>
        <item>
            <title>Anatomy main index</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anatomy</link>
            <description>Anatomy main index

	* autonomic nervous system
	* Gray's anatomy plates on wikipedia
	* Youtube videos on anatomy by &quot;The Noted Anatomist&quot;
	* &lt;https://emergencymedicineireland.com/anatomy-and-em&gt;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Sep 2022 09:13:45 +0000</pubDate>
        </item>
        <item>
            <title>Anatomy for clinical radiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anatrad</link>
            <description>Anatomy for clinical radiology

see also Anatomy main index, radiology</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 30 Sep 2008 14:08:31 +0000</pubDate>
        </item>
        <item>
            <title>antineutrophil cytoplasmic antibodies (ANCAs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anca</link>
            <description>antineutrophil cytoplasmic antibodies (ANCAs)

see also:

	* vasculitis
	* complement C3, C4 testing

introduction

	* these antibodies characteristically occur in vasculitic syndromes
		* occur in more than 90% of patients with systemic Wegener's granulomatosis (with renal or pulmonary involvement, or both), 75% of patients with limited Wegener's granulomatosis (without renal involvement) and 50% of patients with microscopic polyarteritis.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Dec 2015 04:31:43 +0000</pubDate>
        </item>
        <item>
            <title>androgens</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=androgens</link>
            <description>androgens

see also:

	* oestrogens
	* progestogens
	* anabolic steroids
	* androgen deficiency, the male menopause, etc
	* 2025: Review article: Testosterone and men's health: An in-depth exploration of their relationship

introduction

	* androgens are substances that directly result in androgenic effects

androgenisation may occur via:

	* increased bioavailable androgen levels:
		* increased free testosterone:
			* increased total testosterone:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 02 Sep 2025 03:31:59 +0000</pubDate>
        </item>
        <item>
            <title>androgen deficiency</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=androgen_defic</link>
            <description>androgen deficiency

see also:

	*  androgens
	* 2025: Review article: Testosterone and men's health: An in-depth exploration of their relationship

introduction

	* clinical picture depends on when the androgen deficiency begins:
		* pre-pubertal =&gt; eunuchoidism
			* tall (as epiphyses remain open), narrow shoulders, small muscles, adult female body habitus, small genitalia, high-pitched voice, sparse pubic &amp; axillary hair with female pattern</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 02 Sep 2025 03:32:59 +0000</pubDate>
        </item>
        <item>
            <title>vertebral artery aneurysm</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aneurysm_vertebral</link>
            <description>vertebral artery aneurysm

see also:

	* vertebral artery dissection
	* non-traumatic upper neck pain

Introduction

	* these are rare aneurysms which usually develop intracranially at the junction of the vertebral artery and posterior inferior cerebellar artery (PICA) which account for 0.5-3% of intracranial aneurysms</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Apr 2019 00:03:23 +0000</pubDate>
        </item>
        <item>
            <title>angina</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=angina</link>
            <description>angina

see also:

	* ischaemic heart disease (IHD)
	* the adult patient with chest pain in the ED
	* acute coronary syndromes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Dec 2015 04:15:43 +0000</pubDate>
        </item>
        <item>
            <title>angioedema</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=angioedema</link>
            <description>angioedema

see also:

	* hereditary angioedema (HAE)
	* anaphylaxis
	* Emedicine - angioedema
	* RCH guideline - angioedema - C1 esterase inhibitor deficiency

introduction

	* angioneurotic oedema is the acute swelling of mucosal surfaces due to release of inflammatory mediators
	* it may be rapidly life threatening if it involves airway structures
	* most cases are associated with urticaria and are due to</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 08 Feb 2014 07:01:54 +0000</pubDate>
        </item>
        <item>
            <title>angiostrongyliasis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=angiostrongyliasis</link>
            <description>angiostrongyliasis

see also:

	* parasites
	* travel medicine
	* meningitis

introduction

	* Angiostrongyliasis is the most common cause of eosinophilic meningitis in SE Asia and Pacific Basin.
	* it is caused by Angiostrongylus cantonensis, a nematode (roundworm) parasite which resides in pulmonary arteries of rats.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Jan 2012 23:10:50 +0000</pubDate>
        </item>
        <item>
            <title>angiotensin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=angiotensin</link>
            <description>angiotensin

see also:

	* renin
	* aldosterone
	* ACE inhibitors
	* renin-angiotensin system inhibitors (RAS)



image courtesy of wikipedia

introduction

	* angiotensin II is a peptide hormone that produces vasoconstriction, promotes water and salt retention, increased BP, and stimulates release of aldosterone
	* circulating inactive angiotensinogen is a globulin produced by the liver and converted to inactive angiotensin I by</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 03:56:40 +0000</pubDate>
        </item>
        <item>
            <title>animal bites in Australia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=animal_bites</link>
            <description>animal bites in Australia

see also:

	* toxins and envenomations
	* insect bites and stings
	* marine stings in Australia

introduction

	* ~64% of Australian households have a pet
	* ~50% of Australians will have an animal bite in their lifetime
	* ~2% of Australians will be bitten in any one year with 1-2 dying from an animal bite (usually children bitten on head and neck)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Jul 2025 00:43:09 +0000</pubDate>
        </item>
        <item>
            <title>anion gap</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anion_gap</link>
            <description>anion gap

see also:

	* arterial and venous blood gases (ABGs/VBGs)
	* metabolic acidosis

introduction

	* anion gap is a calculated quantity used to assist in the Dx of metabolic acidosis
	* anion gap = ( [Na+]+[K+] ) − ( [Cl−]+[HCO3−] )
	* the average anion gap for healthy adults is 8-12 mEq/L

high anion gap

	* a high anion gap indicates that there is loss of HCO3− without a concurrent increase in Cl−.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 18 Jan 2010 02:44:16 +0000</pubDate>
        </item>
        <item>
            <title>ano-rectal pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anorectal_pain</link>
            <description>ano-rectal pain

see also:

	* perianal abscess
	* perirectal abscess
	* haemorrhoids
	* anal fissure
	* anal fistula / fistula-in-ano
	* proctitis
	* PR_exam

	* BEWARE: severe pain but no local signs may be due to other anorectal abscess sites such as an intersphincteric abscess!

Aetiology of ano-rectal pain

	* thrombosed external haemorrhoid
	* anal fissure
	* perianal abscess
	* perirectal abscess
		*  ischio-rectal abscess</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2026 05:22:26 +0000</pubDate>
        </item>
        <item>
            <title>anorexia nervosa</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anorexia_nervosa</link>
            <description>anorexia nervosa

see also:

	* RCH guideline - anorexia nervosa

Introduction

	* an eating disorder defined by:
		*  persistent energy intake restriction
		*  intense fear of weight gain or persistent behaviour that interferes with weight gain
		*  and a disturbance of body image</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:46:16 +0000</pubDate>
        </item>
        <item>
            <title>anovulation and anovulatory menstrual cycles</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anovulation</link>
            <description>anovulation and anovulatory menstrual cycles

see also:

	* gynaecology
	* menstrual cycle

Introduction

	* anovulatory cycles are common and have many causes and many clinical consequences due to failure of the high-fertility phase of ovulation, the typical “peak” in libido and cervical mucus changes (lubrication), failure to create a corpus luteum which would normally produce progesterone and either low oestrogen or unopposed high oestrogen</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Jan 2026 00:51:11 +0000</pubDate>
        </item>
        <item>
            <title>anti-androgens</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antiandrogen</link>
            <description>anti-androgens

see also androgens; androgen deficiency

Introduction

	* anti-androgens have differing extent of actions depending on level of action:
		* GnRH agonists that block LH secretion:
			* by providing continuous rather than pulsatile activity, these agents lower LH secretion, &amp; although lower testosterone levels by 90% at 1 month, they often transiently increase levels initially</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Dec 2017 04:49:18 +0000</pubDate>
        </item>
        <item>
            <title>anti-arrhythmic agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antiarrhythmics</link>
            <description>anti-arrhythmic agents

see also:

	* pharmacology main index
	* cardiology
	*  History of anti-arrhythmic agents
	* cardiac arrhythmias
	*  Paediatric Resuscitation Drugs

Vaughan-Williams Classification of Anti-Arrhythmic Drugs:

	* 1st proposed in 1970

Class I: Na channel blockade

A: Prolong AP Duration &amp; thus QRS, QTc &amp; thus tend to cause torsades de pointes in toxicity</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Oct 2013 02:34:49 +0000</pubDate>
        </item>
        <item>
            <title>antibiotics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antibiotics</link>
            <description>antibiotics

see also:

	* clinically important bacteria
	* penicillins
	* cephalosporins
	* tetracycline antibiotics
	* macrolide antibiotics
	* aminoglycoside antibiotics
	* flouroquinolone antibiotics
	* antibiotics used to treat TB
	* antibiotics for Rx of Staph. aureus
	* Urinary Antiseptics
	* antibiotic doses for peritoneal dialysis patients
	* antibiotic resistance
	* RCH guidelines - antibiotics

beta lactam ring antibiotics:

	* These drugs attack the bacterial cell wall with bacterici…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 22 Feb 2026 04:14:00 +0000</pubDate>
        </item>
        <item>
            <title>antibiotics for Rx of Staph. aureus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antibiotics_staph</link>
            <description>antibiotics for Rx of Staph. aureus

see also:

	* antibiotics
	* staphylococcus
	* wikipedia - MRSA

non-MRSA organisms

beta lactamase resistant penicillins

	* flucloxacillin
	* dicloxacillin
	* methicillin
	* penicillins combined with beta lactamase inhibitors such as clavulanic acid, sulbactam, tazobactam</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 09 Jan 2012 02:59:55 +0000</pubDate>
        </item>
        <item>
            <title>antibiotics used to treat TB</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antibiotics_tb</link>
            <description>antibiotics used to treat TB

see also:

	* tuberculosis (TB)
	* antibiotics

Isoniazid

	* a hydrazide of isonicotinic acid, discovered in 1945 after nicotinamide shown to have anti-TB action
	* remarkably selective for TB, and is the primary drug used in Rx of TB
	* bacteriostatic for resting bacteria but bactericidal for rapidly dividing bacteria</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 Jun 2023 22:47:12 +0000</pubDate>
        </item>
        <item>
            <title>antibiotic resistance</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antibiotic_resistance</link>
            <description>antibiotic resistance

see also:

	* antibiotics
	* clinically important bacteria
	* Australia's National Alert System for Critical Antimicrobial Resistances: CARAlert
	* the Australian Group on Antimicrobial Resistance (AGAR) website
	* Australian Prescriber 2004: Antibiotic prescribing: how can emergence of antibiotic resistance be delayed?
	* WHO main page on drug resistance
	* WHO report 2014 (pdf) 

introduction

	* whenever antibiotics are used, this puts biological pressure on bacteria th…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 10 Jul 2019 00:44:56 +0000</pubDate>
        </item>
        <item>
            <title>anti-muscarinic anticholinergic agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anticholinergics</link>
            <description>anti-muscarinic anticholinergic agents

see also:

	* pharmacology main index
	*  parasympathetics - the actions of muscarinic receptors

Summary of anticholinergic effects:

	* mydriasis, cycloplegia, tachycardia, antispasmodic GIT;
		* dry mouth, decr. fasting gastric acid secretion; decr. motility;
		* dilates pelves, calyces, ureters, bladder;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Aug 2019 03:45:20 +0000</pubDate>
        </item>
        <item>
            <title>anticoagulants</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anticoagulants</link>
            <description>anticoagulants

see also:

	* pharmacology main index
	* historical perspectives
	* warfarin
	* heparin
	* enoxaparin (Clexane)
	* General anticoagulation guidelines
	* antithrombotic Rx for prevention of stroke
	* Mx of lower limb DVT
	* atrial fibrillation
	* anticoagulation
	* RCH guidelines - anticoagulation therapy in children

traditional oral anticoagulants

Mechanism of action:

	* orally active agents that block the reductive re-activation of vitamin K epoxide back to its active hydroqu…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Nov 2022 05:06:47 +0000</pubDate>
        </item>
        <item>
            <title>general anticoagulation guidelines</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anticoagulant_guidelines</link>
            <description>general anticoagulation guidelines

see also:

	* anticoagulants
	* antithrombotic Rx for prevention of stroke
	* Mx of PE
	* Mx of excessive anticoagulation, high INR, or bleeding on warfarin Rx

derived from: Western Health guidelines on warfarin Rx (pdf) - only available within WH intranet

Before initiating warfarin Rx

	* consider if the benefits of anticoagulation outweigh its risks, such as bleeding, for each patient
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 26 Aug 2014 12:50:22 +0000</pubDate>
        </item>
        <item>
            <title>anticoagulation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anticoagulation</link>
            <description>anticoagulation

see anticoagulants</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 May 2014 05:48:41 +0000</pubDate>
        </item>
        <item>
            <title>anticonvulsants</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anticonvulsants</link>
            <description>anticonvulsants

see also:

	* seizures and Mx
	* pharmacology main index
	* RCH therapeutic drug level monitoring guidelines (pdf)
	* anticonvulsant overdose/poisoning

General Mx principles

weaning anticonvulsants

	* withdrawal of anticonvulsant Rx in seizure-free patients

missed tablets:

	* in general, if it is time for next dose within next 4hours, skip the missed dose &amp; take next dose when it is due, otherwise take the missed tablet</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jan 2026 04:07:00 +0000</pubDate>
        </item>
        <item>
            <title>antidepressants</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antidepressants</link>
            <description>antidepressants

see also:

	* SSRI/SNRI antidepressants
	* tricyclic antidepressants
	* tetracyclics
	* monoamine oxidase inhibitors (MAOIs)
	* depression
	* psychiatry and mental health
	* pharmacology main index
	* tricyclic antidepressant overdose
	* 2015 Brain Resource Depression Treatment Test: choosing the best antidepressant via patient questionnaire

Other references

	* Aust Presc 2007 - Antidepressants in pregnancy and breastfeeding</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 05 Mar 2015 23:40:08 +0000</pubDate>
        </item>
        <item>
            <title>anti-emetics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antiemetics</link>
            <description>anti-emetics

see also:

	* vomiting / emesis
	* metoclopramide (Maxolon)
	* ondansetron
	* prochlorperazine (Stemetil)
	* domperidone (Motilium)

	* antiemetics appear to be only marginally better than iv N Saline placebo for ED patients excluding those with hyperemesis gravidarum, chemotherapy, or vertigo aetiologies 
metoclopramide (Maxolon)
	* metoclopramide should not be used in children as the risk of dystonic reactions such as oculogyric crises is high.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Jan 2017 23:06:48 +0000</pubDate>
        </item>
        <item>
            <title>antifungal agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antifungals</link>
            <description>antifungal agents

see also:

	* fungi
	* tinea fungal infections
	* antibiotics

introduction

	* oral antifungals other than nystatin generally have potentially serious adverse effects and important drug interactions.
		* reserve these antifungals for:
			* widespread or chronic, mycologically confirmed superficial fungal infection not responding to repeated topical Rx</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Feb 2026 10:53:18 +0000</pubDate>
        </item>
        <item>
            <title>antihistamines (H1)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antihistamines</link>
            <description>antihistamines (H1)

see also:

	* histamine physiology, receptors and antihistamines
	* allergy and hypersensitivity reactions
	* H2-type antihistamines

introduction

	* 1st discovered 1937 but useful ones in 1950;
		* The “classical” antihistamines have similar activity:
			* decr. most smooth muscle response to histamine;
			* decr. rapid vasodilatory action via endoth.cells;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 Mar 2023 07:46:08 +0000</pubDate>
        </item>
        <item>
            <title>H2-type antihistamines</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antihistamines_h2</link>
            <description>H2-type antihistamines

see also:

	* histamine physiology, receptors and antihistamines
	* PU

introduction

	* H2 receptor antagonists are primarily used to reduce gastric acid secretion in the Rx of PU and gastritis

cimetidine

ranitidine</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 May 2012 06:58:30 +0000</pubDate>
        </item>
        <item>
            <title>antihypertensives</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antihypertensives</link>
            <description>antihypertensives

see also:

	* hypertension

introduction

	* the main groups of antihypertensive agents are:
		* vasodilators:
			* direct acting such as calcium channel blockers, hydralazine, sodium nitroprusside, potassium channel agents such as minoxidil, diazoxide and nicorandil
			* indirect acting such as clonidine (Catapres), methyldopa, ACE inhibitors, angiotensin II receptor blockers (ARBs), angiotensin receptor–neprilysin inhibitors (ARNIs)

		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 02:41:16 +0000</pubDate>
        </item>
        <item>
            <title>antioestrogens</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antioestrogens</link>
            <description>antioestrogens

see also:

	* oestrogens
	* tamoxifen
	* antiprogestogens

Introduction</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 09 Jun 2019 01:51:19 +0000</pubDate>
        </item>
        <item>
            <title>antiplatelet agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antiplatelet</link>
            <description>antiplatelet agents

see also:

	* anticoagulants
	* antithrombotic Rx for prevention of stroke
	* Mx of possible acute coronary syndrome without ST elevation (NSTEACS)
	* acute myocardial infarction (AMI/STEMI/NSTEMI)

aspirin

	* see aspirin (acetylsalicylic acid) (acetylsalicylic acid)
	* It inhibits platelets by irreversibly covalently acetylating the active site of cyclooxygenase which is the enzyme that produces the cyclic endoperoxide precursor of thromboxane A2.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Dec 2014 05:23:11 +0000</pubDate>
        </item>
        <item>
            <title>antiprogestogens</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antiprogestogens</link>
            <description>antiprogestogens

see also:

	* progestogens

introduction

	* progesterone receptor antagonists used to induce miscarriage

mifepristone

	* RU486 or mifepristone is a progestogen receptor antagonist which can induce abortion, causes dilatation of the cervix, and increases sensitivity of the myometrium to prostaglandins</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Sep 2013 08:33:00 +0000</pubDate>
        </item>
        <item>
            <title>anti-psychotic medications</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antipsychotics</link>
            <description>anti-psychotic medications

see also:

	* psychiatry and mental health
	* bipolar disorder
	* schizophrenia
	* Aust Prescr 2007 - Antipsychotic drugs in pregnancy and breastfeeding

introduction:

	* reserpine &amp; chlorpromazine (Largactil) were the 1st drugs used in schizophrenia, but their use has been superseded by newer drugs.
	* like tricyclic antidepressants, in general, major tranquillisers have similar P/K characteristics:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 01 Oct 2017 11:52:15 +0000</pubDate>
        </item>
        <item>
            <title>antiretroviral agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antiretrovirals</link>
            <description>antiretroviral agents

see also:

	* viruses
	* HIV / AIDS
	* Aust Presc 2008 - HIV fusion inhibitors: a review
	* Aust Presc 2005 - New developments in antiretroviral Rx in HIV</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Dec 2011 04:44:36 +0000</pubDate>
        </item>
        <item>
            <title>antitussive cough medications</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antitussives</link>
            <description>antitussive cough medications

see also:

	* pholcodine - withdrawn in 2023
	* codeine

Introduction

	* antitussives are used to suppress non-productive coughs</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 11 Apr 2023 06:33:55 +0000</pubDate>
        </item>
        <item>
            <title>antiviral agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=antivirals</link>
            <description>antiviral agents

see also:

	* viruses
	* HIV / AIDS
	* Herpes simplex virus (HSV)
	* varicella-zoster virus (chickenpox/shingles)
	* meningitis

herpes virus and varicella virus antiviral agents

	* aciclovir and related antivirals (famciclovir, valaciclovir)
	* famciclovir
	* valaciclovir

HIV antiviral agents

	* see antiretroviral agents</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Dec 2011 04:43:42 +0000</pubDate>
        </item>
        <item>
            <title>the patient unable to pass urine (anuria)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anuria</link>
            <description>the patient unable to pass urine (anuria)

see also:

	* urology
	* acute urinary retention
	* acute kidney injury (AKI) / acute renal failure (ARF)
	* the shocked hypotensive patient

introduction

	* inability to pass urine is a common ED presentation, and as with renal failure falls into 3 main categories:
		*  acute urinary retention
		*  pre-renal causes such as the shocked hypotensive patient
		*  renal causes (</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 10 Aug 2016 08:12:12 +0000</pubDate>
        </item>
        <item>
            <title>anxiety disorders, panic attacks, hyperventilation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=anxiety</link>
            <description>anxiety disorders, panic attacks, hyperventilation

see also:

	* stress
	* psychiatry and mental health

introduction

	* all people have periods of anxiety
	* it may become troublesome and regarded as a disorder if it becomes persistent, or is out of proportion to what would be expected and interferes with functioning.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 14 Nov 2025 11:05:13 +0000</pubDate>
        </item>
        <item>
            <title>aortic dissection</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aorticdissection</link>
            <description>aortic dissection

see also:

	*  chest pain in the ED; 
	*  ADD - an aortic dissection risk assessment tool
	*  Features and diagnosis of aortic dissection
	* AFTB lecture notes - aortic dissection

management in the ED:

	* mortality in 1st 24-48hrs is 1-2% per hour
	* all pts with suspected dissection should have careful monitoring of:
		* ECG
		* BP - preferably with arterial line
		* urine output</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 23 Aug 2022 07:09:21 +0000</pubDate>
        </item>
        <item>
            <title>D-Dimer and aortic dissection</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aorticdissection_ddimer</link>
            <description>D-Dimer and aortic dissection

see also:

	* aortic dissection
		* aortic dissection features and diagnosis
		* ADD - an aortic dissection risk assessment tool

Introduction

	* D-Dimer is usually elevated in acute cases of aortic dissection with 91-97% sensitivity but is poorly specific, and not sufficiently sensitive that a negative D-Dimer will exclude dissection in those with high risk features, but</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 04 Sep 2017 07:43:01 +0000</pubDate>
        </item>
        <item>
            <title>aortic dissection features and diagnosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aorticdissection_dx</link>
            <description>aortic dissection features and diagnosis

see also:

	*  ADD - an aortic dissection risk assessment tool
	*  Mx of aortic dissection
	*   chest pain in the ED
	*   EMedicine

historical perspective:

	* in 1761, Nicholls described aortic dissection in an autopsy on the body of Kng George II of England, who is reported to have died straining at stool.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Oct 2025 01:24:31 +0000</pubDate>
        </item>
        <item>
            <title>thoracic aortic aneurysm</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aortic_aneurysm_tx</link>
            <description>thoracic aortic aneurysm

see also:

	* vascular surgery
	* aortic dissection
	* abdominal aortic aneurysm (AAA)
	* ANZSVS patient information on TAAs and AAAs

Introduction

	* aneurysm of the thoracic aorta is much less common than abdominal aortic aneurysm (AAA) and mainly occurs in those over the age of 60 yrs, although may occur in patients younger than 40yrs if they have a predisposing condition</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Dec 2023 23:02:37 +0000</pubDate>
        </item>
        <item>
            <title>ADD - an aortic dissection risk assessment tool</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aortic_dissection_add</link>
            <description>ADD - an aortic dissection risk assessment tool

see also:

	* aortic dissection
		* aortic dissection features and diagnosis
		* D-Dimer and aortic dissection
		* the adult patient with chest pain in the ED

	*  there are no prospectively tested rules to risk stratify chest pain for the risk of dissecting aortic aneurysm 
	* the ADD score is unlikely to be a useful tool in the ED given its very low specificity although a negative D-Dimer does make this tool much more useful for those with score…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Sep 2024 13:12:16 +0000</pubDate>
        </item>
        <item>
            <title>aortic stenosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aortic_stenosis</link>
            <description>aortic stenosis

see also:

	* left ventricular hypertrophy (LVH)
	* valvular_heart_disease

Introduction

	* this condition mainly presents in the elderly and is the most common heart valve disease in the elderly
	* those with calcified biscuspid valves which accounts for 30-40% of cases, often present at age 40-60yrs</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 26 Jun 2025 01:05:37 +0000</pubDate>
        </item>
        <item>
            <title>thrombosis of the aorta</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aortic_thrombosis</link>
            <description>thrombosis of the aorta

see also:

	* peripheral vascular disease (PVD or PAD)
	* aortic dissection
	* abdominal aortic aneurysm (AAA)
	* vascular surgery

Introduction

	* acute occlusion of the aorta by thrombosis is a rare life threatening event causing severe distal ischaemia (eg. acute limb ischaemia and renal infarct / infarction) and high risk of distal emboli
	* chronic complete occlusions of a AAA are rare but may be asymptomatic</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 12 Apr 2023 06:26:41 +0000</pubDate>
        </item>
        <item>
            <title>apixaban</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=apixaban</link>
            <description>apixaban

see also:

	* anticoagulants
	* rivaroxaban

introduction

	* a trial of the new oral factor Xa inhibitor, apixaban showed that it reduced stroke risk by more than 50% when compared to aspirin alone (3.4% per year on aspirin, 1.6% per year on apixaban), whilst increasing risk of major bleeding from 1.2% per year on aspirin to 1.4% per year on apixaban 5mg bd</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Mar 2026 04:56:03 +0000</pubDate>
        </item>
        <item>
            <title>aplastic anaemia / pancytopenia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aplastic_anaemia</link>
            <description>aplastic anaemia / pancytopenia

see also:

	* haematology
	* neutropenia

Introduction

	* aplastic anaemia is an auto-immune, rare (1-4 per million population) life threatening disorder in which the stem cells in bone marrow are destroyed leading to severe anaemia, thrombocytopenia and agranulocytosis (ie. pancytopenia)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 24 Mar 2024 13:21:50 +0000</pubDate>
        </item>
        <item>
            <title>acute pulmonary oedema (APO)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=apo</link>
            <description>acute pulmonary oedema (APO)

see also:

	* cardiology
	* congestive cardiac failure
	* Mx of the wheezy elderly patient - acute pulmonary oedema versus asthma
	* AFTB lectures - APO
	* non-invasive positive pressure ventilation (NIPPV)

Rx aims

	* improve cardiac function:
		* correct hypoxaemia
			* supplemental oxygen
			* correct acute respiratory failure

		* promote coronary blood flow
		* reduce LV diastolic pressure via:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Jun 2014 08:13:01 +0000</pubDate>
        </item>
        <item>
            <title>Mx of the wheezy elderly patient - acute pulmonary oedema versus asthma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=apo_vs_asthma</link>
            <description>Mx of the wheezy elderly patient - acute pulmonary oedema versus asthma

see also:

	* cardiology
	* acute pulmonary oedema (APO)
	* asthma

Introduction

	* the undifferentiated acutely short of breath elderly patient with a wheeze is a common problem in the ED
	* whilst many patients will be able to be rapidly placed into a diagnostic category based on PH, other clinical features which allows targeted acute Rx, in many, the cause of the acute SOB is often not initially clear and a</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 15 Jul 2009 05:08:53 +0000</pubDate>
        </item>
        <item>
            <title>appendiceal faecoliths</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=appendiceal_faecoliths</link>
            <description>appendiceal faecoliths

see also:

	* the patient with acute abdominal pain in the ED
	* appendicitis
	* general surgery

Introduction

	* appendicitis is mainly a disease of Western societies with lower fibre diets which result in harder, drier stools and is rare in traditionally living Africans and Indians.
	* it is thought that obstructing faecoliths may be an aetiologic factor especially in children although some studies appear to refute this</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 22 Jan 2019 05:40:17 +0000</pubDate>
        </item>
        <item>
            <title>appendicitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=appendicitis</link>
            <description>appendicitis

see also:

	* the patient with acute abdominal pain in the ED
	* appendiceal faecoliths
	* general surgery

clinical features

	* pain initially epigastric and migrated to RIF with anorexia, nausea +/- low grade fever
	* max. tenderness over McBurney's point
	* +/- Rovsing's sign - rebound tenderness LIF
	* +/- psoas sign (pain on passive extension of the right hip) - esp. likely in retrocaecal appendicitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 21 Jan 2019 01:43:35 +0000</pubDate>
        </item>
        <item>
            <title>Airway Pressure Release Ventilation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aprv</link>
            <description>Airway Pressure Release Ventilation

see also:

	* assisted ventilation

Why learn about APRV?

Airway Pressure Release Ventilation is easy to set up and comfortable for patients. There is some research to show that it reduces alveolar inflammation and progression to lung injury for mechanically ventilated patients. The mechanisms behind Ventilator Induced Lung Injury (VILI) are still being studied. APRV appears beneficial due to decreased atelectatrauma.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Jan 2021 13:15:15 +0000</pubDate>
        </item>
        <item>
            <title>activated partial thromboplastin time (APTT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aptt</link>
            <description>activated partial thromboplastin time (APTT)

see also:

	* anticoagulants
	* INR

introduction

	* the APTT test measures the overall activity of the intrinsic coagulation pathway.
	* performed by warming a thromboplastin reagent that contains phospholipid with an aliquot of the patient's plasma, and then recalcifying this mixture after a set incubation period.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 Sep 2009 04:45:46 +0000</pubDate>
        </item>
        <item>
            <title>arachnoid cysts</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arachnoid_cysts</link>
            <description>arachnoid cysts

see also:

	* CT brain

Introduction

	* arachnoid cysts are incidental findings on CT brain or MRI scans of the brain
	* prevalence is ~1.4%
	* rarely they may be symptomatic - usually in childhood 
	* they are thought to arise from a congenital splitting of the arachnoid layer and thus form very thinly lined cystic spaces which are filled with CSF</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Jan 2026 21:59:38 +0000</pubDate>
        </item>
        <item>
            <title>angiotensin II receptor blockers (ARBs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arbs</link>
            <description>angiotensin II receptor blockers (ARBs)

see also:

	* ACE inhibitors
	* antihypertensives
	* hypertension
	* angiotensin receptor–neprilysin inhibitors (ARNIs)

Introduction

	* ARBs were developed to address the issue that some patients taking ACE inhibitors developed bradykinin-mediated angioedema or cough
	* ACE inhibitors act by blocking the formation of angiotensin II whereas ARBs act by blocking the actions of angiotensin II</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 01:53:24 +0000</pubDate>
        </item>
        <item>
            <title>Acute Respiratory Distress Syndrome (ARDS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ards</link>
            <description>Acute Respiratory Distress Syndrome (ARDS)

see also:

	* respiratory medicine
	* ARDSnet.org
	* Chestnet.org - Pulmonary complications of blast injury and its Mx

mechanical ventilation in ARDS

&quot;APRV&quot;

	* international research to suggest early use of Airway Pressure Release Ventilation (APRV) may decrease atelectatrauma and ventilator induced lung injury (VILI)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 10 Jun 2020 11:25:16 +0000</pubDate>
        </item>
        <item>
            <title>acute kidney injury (AKI) / acute renal failure (ARF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arf</link>
            <description>acute kidney injury (AKI) / acute renal failure (ARF)

see also:

	* renal medicine (nephrology)
	* chronic renal failure
	* pathology tests - urea and creatinine
	* urinalysis

introduction

	* ARF is a common finding in the ED patient and one of the clinician's tasks is to decide on whether it is pre-renal, renal or post-renal.
	* exclusion of urinary retention by checking with a bladder scanner is a simple first step</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 12 Jul 2023 01:53:18 +0000</pubDate>
        </item>
        <item>
            <title>angiotensin receptor–neprilysin inhibitors (ARNIs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arnis</link>
            <description>angiotensin receptor–neprilysin inhibitors (ARNIs)

see also:

	* congestive cardiac failure
	* hypertension
	* angiotensin II receptor blockers (ARBs)
	* hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers

Introduction

	* angiotensin receptor–neprilysin inhibitors (ARNIs) are a new class of cardiovascular agents characterized by their dual action on the major regulators of the cardiovascular system, including the renin–angiotensin system (RAS) and the natriuretic peptid…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 02:42:55 +0000</pubDate>
        </item>
        <item>
            <title>cardiac arrhythmias</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arrhythmias</link>
            <description>cardiac arrhythmias

see also:

	* choking / respiratory arrest / cardiac arrest / BLS / ALS / CPR
	* cardiology
	* palpitations
	* anti-arrhythmic agents
	*  Paediatric Resuscitation Drugs
	* basics of the ECG
	* hypokalaemia
	* hyperkalaemia
	* LITFL - ECG rhythms

arrhythmias

	*  Narrow Complex Tachycardias Mx and DDx
	*  Broad Complex Tachycardias Mx and DDx

	*  AV block
	*  Bradycardia
	* sinus tachycardia
	*  Supraventricular tachycardias (SVT)
	* Pre-excitation syndromes such as WPW
	* …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 09 Sep 2023 08:10:59 +0000</pubDate>
        </item>
        <item>
            <title>artemether /lumefantrine anti-malarial</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=artermether</link>
            <description>artemether /lumefantrine anti-malarial

see also:

	* malaria

introduction

	* artemether is an anti-malarial usually combined with lumefantrine (marketed as Riamet)
		* this combination is the 1st line Rx in 2015 for uncomplicated falciparum malaria and for vivax acquired in Indonesia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:48:02 +0000</pubDate>
        </item>
        <item>
            <title>arthritis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arthritis</link>
            <description>arthritis

see also:

	* arthritis - clinical patterns
	* rheumatoid arthritis
	* the swollen joint and its diagnostic workup
	* rheumatology</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Dec 2015 04:17:33 +0000</pubDate>
        </item>
        <item>
            <title>extra-articular clinical features of rheumatologic conditions</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arthritis_extraarticular</link>
            <description>extra-articular clinical features of rheumatologic conditions

see also:

	* rheumatology

introduction

	* see also arthritis - clinical patterns for more details on patterns of disease in arthritis
	* the following is a quick aide memoire of the common conditions which cause joint swelling and some of their extra-articular manifestations which may provide clues to the diagnosis.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 13 Jul 2019 17:12:24 +0000</pubDate>
        </item>
        <item>
            <title>assessment of joint function and arthritis severity</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arthritis_function</link>
            <description>assessment of joint function and arthritis severity

see also:

	* rheumatology
	* the swollen joint and its diagnostic workup

assessment of joint function

modified ARA criteria:

	* ARA I:
		* normal joint function = no disease

	* ARA II:
		* adequate function despite symptoms = early disease

	* ARA III:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Sep 2009 09:39:15 +0000</pubDate>
        </item>
        <item>
            <title>arthritis - clinical patterns</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arthritis_patterns</link>
            <description>arthritis - clinical patterns

see also:

	* rheumatology
	* back pain in the ED
	* the swollen joint and its diagnostic workup
	* assessment of joint function and arthritis severity
	* extra-articular clinical features of rheumatologic conditions

introduction

	* the patient with joint pain needs to be carefully evaluated to determine the most likely cause
	* is it a single joint involvement or multiple joints, and if so, what is the pattern of joint involvement?</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 23 Feb 2025 00:34:09 +0000</pubDate>
        </item>
        <item>
            <title>reactive arthritis (Reiter's syndrome)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arthritis_reactive</link>
            <description>reactive arthritis (Reiter's syndrome)

see also:

	* arthritis - clinical patterns
	* spondyloarthopathies
	* uveitis

introduction

	* reactive arthritis refers to an acute inflammatory aseptic arthritis complicating an infection elsewhere in the body.
	* 60-85% of patients are HLA-B27 positive
	* Reiter's syndrome was a term used to describe a subset of these patients who developed:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Oct 2013 02:50:53 +0000</pubDate>
        </item>
        <item>
            <title>septic arthritis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arthritis_septic</link>
            <description>septic arthritis

see also:

	* osteomyelitis
	* the swollen joint and its diagnostic workup
	* Phong Tran's website - septic arthritis

Introduction

	* septic arthritis is one of those diagnoses you do not want to miss
	* delay in diagnosis may cause joint damage as well as life threatening sepsis / septicaemia
	* unfortunately, many other conditions cause a hot, swollen joint, and some with associated fevers</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 26 Mar 2018 06:06:22 +0000</pubDate>
        </item>
        <item>
            <title>The art of being an ED doctor</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=art_of_ed</link>
            <description>The art of being an ED doctor

see also:

	* How to break bad news - by Doc Gurley
	* thoughts of the cardiac arrest team leader - by the Happy Hospitalist</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 19 Dec 2008 09:04:45 +0000</pubDate>
        </item>
        <item>
            <title>Arrythmogenic Right Ventricular Dysplasia (ARVD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=arvd</link>
            <description>Arrythmogenic Right Ventricular Dysplasia (ARVD)

see also:

	* syncope / near syncope
	* patterns of ECGs

Introduction

	* genetic disease of desmosome dysfunction resulting in the progressive replacement of the RV myocardium by fatty fibrous tissue which slows cardiac impulse conduction through the RV</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 10 Apr 2017 00:57:56 +0000</pubDate>
        </item>
        <item>
            <title>ankylosing spondylitis (AS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=as</link>
            <description>ankylosing spondylitis (AS)

see also:

	* connective tissue (CT) disorders
	* arthritis - clinical patterns
	* spondyloarthopathies
	* back pain in the ED
	* wikipedia

introduction

	* one of the seronegative spondyloarthropathies with a strong genetic predisposition which appears to relate to the ARTS1 and IL23R genes in addition to HLA-B27
		*  elevated KIR2DS5 gene expression inhibits the development of endometriosis, AS and psoriasis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Mar 2024 14:15:57 +0000</pubDate>
        </item>
        <item>
            <title>ascites</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ascites</link>
            <description>ascites

see also gastroenterology, cirrhosis

Pathogenesis

	* usually transudative due to either:
		* elevated portal venous pressures
		* hypoalbuminaemia
		* enhanced renal retention of sodium

	* uncommonly, it is exudative as in:
		* spontaneous bacterial peritonitis (SBP)
		* neoplasia / cancer / tumours such as:
			* hepatocellular carcinoma
			* peritoneal carcinomatosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 17 Aug 2013 14:32:32 +0000</pubDate>
        </item>
        <item>
            <title>aseptic non-touch technique (ANTT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=asepsis</link>
            <description>aseptic non-touch technique (ANTT)

see also:

	* clinically important bacteria
	* hand hygiene for health workers
	* prevention of infection in healthcare - standard precautions
	* sterilisation
	* fire and emergency procedures

introduction

	* aseptic non-touch technique is critical in reducing risk of iatrogenic infections in healthcare

WHO Five Moments of hand hygiene

	* before attending to a patient
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 22 Jun 2023 05:22:20 +0000</pubDate>
        </item>
        <item>
            <title>African swine fever virus (ASFV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=asfv</link>
            <description>African swine fever virus (ASFV)

see also:

	* viruses

Introduction

	* African Swine Fever virus is a highly virulent DNA virus that causes a severe hemorrhagic disease of the same name affecting both domestic pigs and wild boars with high mortality rates</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 05 Jun 2025 00:49:37 +0000</pubDate>
        </item>
        <item>
            <title>Asperger's syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aspergers</link>
            <description>Asperger's syndrome

see also:

	* autism spectrum disorder (ASD)
	* attention deficit hyperactivity disorder (ADHD)

introduction

	* a developmental disorder which in DSM V will be included with autism spectrum disorder (ASD) as it is difficult to distinguish from high-functioning autism (HFA)
	* the Austrian pediatrician Hans Asperger in 1944 studied and described children in his practice who:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 02 Sep 2012 09:12:30 +0000</pubDate>
        </item>
        <item>
            <title>Aspergillosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aspergillosis</link>
            <description>Aspergillosis

see also:

	* fungi
	* aspergillus

Introduction

	* a fungal pulmonary infection caused by aspergillus - 90% are due to Aspergillus fumigatus which may have a symbiotic mycovirus which enables it to survive in mammalian lungs 
	* it is caused by inhalation of spores from soil and mainly occurs in immunocompromised people</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Aug 2025 08:27:20 +0000</pubDate>
        </item>
        <item>
            <title>aspergillus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aspergillus</link>
            <description>aspergillus

see also:

	* fungi
	* Aspergillosis

Introduction

	* the aspergillus family of fungi are very common in soils and on plants
	* inhalation of soil is common but in those with weakened immune systems (including those with severe COVID-19 coronavirus (2019-nCoV / SARS-CoV-2), chronic obstructive pulmonary disease (COPD), immunodeficiencies, etc), it may cause pulmonary aspergillomas or</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Aug 2025 08:22:59 +0000</pubDate>
        </item>
        <item>
            <title>aspirin (acetylsalicylic acid)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=aspirin</link>
            <description>aspirin (acetylsalicylic acid)

see also:

	* pain, analgesia and analgesics
	* antiplatelet agents

introduction

	* aspirin has analgesic, antipyretic, anti-inflammatory activity (similar to non-steroidal anti-inflammatory drugs (NSAIDs)), as well as prolonged anti-platelet activity
	* hypersensitivity reactions, particularly bronchospasm, may occur, particularly in those with asthma.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 24 Jan 2013 00:26:30 +0000</pubDate>
        </item>
        <item>
            <title>asthma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=asthma</link>
            <description>asthma

see also:

	* paediatric asthma
	* acute asthma in the adult patient
	* thunderstorm asthma
	* beta 2 adrenergic agonists
	* Mx of the wheezy elderly patient - acute pulmonary oedema versus asthma
	* AFTB's lecture notes - Mx of acute asthma

diagnosis in adults

	* Spirometry is the preferred initial test to assess the presence and severity of airflow obstruction
	* PEFR testing: PEF should be recorded as the best of three forced expiratory blows from total lung capacity with a maximum …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 26 Feb 2024 09:05:52 +0000</pubDate>
        </item>
        <item>
            <title>acute asthma in the adult patient</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=asthma_adult</link>
            <description>acute asthma in the adult patient

see also:

	* paediatric asthma
	* asthma
	* beta 2 adrenergic agonists
	* Mx of the wheezy elderly patient - acute pulmonary oedema versus asthma
	* AFTB's lecture notes - Mx of acute asthma

introduction

	* most patients who die from asthma have chronic severe asthma
	* a minority who die from asthma have mild-mod chronic symptoms and develop a sudden severe attack
	* some die following inappropriate prescribing of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Apr 2024 12:39:13 +0000</pubDate>
        </item>
        <item>
            <title>paediatric asthma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=asthma_paed</link>
            <description>paediatric asthma

see also:

	* paediatric emergency medicine
	* asthma
	* Mx of critically severe paediatric asthma
	* asthma science

patient information sheets

	* RCH - asthma (pdf)
	* RCH - use of spacers (pdf)
	* Vic DHS - paediatric asthma (pdf)

mild asthma

	* SaO2 &gt; 95% in room air on arrival to ED
	* normal mental state and minimal if any recession or use of accessory muscles
	* able to talk normally

Mx in ED</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 28 Jul 2022 22:34:15 +0000</pubDate>
        </item>
        <item>
            <title>Mx of critically severe paediatric asthma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=asthma_paed_severe</link>
            <description>Mx of critically severe paediatric asthma

see also:

	* Mx of less severe asthma

initial management

	* oxygen to maintain SaO2 &gt; 92%
		*  use high flow intranasal oxygen if needed

	* contact senior staff ASAP and move patient to a resuscitation cubicle
	* continuous salbutamol nebulisers</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 07 Jan 2020 02:47:29 +0000</pubDate>
        </item>
        <item>
            <title>asthma science</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=asthma_science</link>
            <description>asthma science

see also:

	* paediatric emergency medicine
	* asthma
	* Mx of critically severe paediatric asthma
	* paediatric asthma
	* immunology
	* adaptive immunity

Risk factors for developing asthma

	* exposure to antibiotics in infancy appears to be a causal factor 
		*  potential role of antibiotic effect upon GIT microbiome and the change in development of the immune system</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Oct 2023 23:16:05 +0000</pubDate>
        </item>
        <item>
            <title>thunderstorm asthma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=asthma_thunderstorm</link>
            <description>thunderstorm asthma

see also:

	* asthma
	* allergens
	* Victorian Thunderstorm asthma forecast risk level and grass pollen counts
	* Vic Govt funding new research Feb 2017
	* The Age: Feb 2017 reporting the Vic Govt's report on the Nov 2016 event
	* Vic Better Health patient information on thunderstorm asthma
	* Vic Govt public awareness toolkit
	* Vic Govt Thunderstorm Asthma webpage

Introduction

	* Thunderstorms may induce a sudden region wide increase in acute asthma in people with a hist…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 16 Apr 2021 07:52:32 +0000</pubDate>
        </item>
        <item>
            <title>medical or mental health care for refugees and asylum seekers in western Melbourne</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=asylum_seekers</link>
            <description>medical or mental health care for refugees and asylum seekers in western Melbourne

see also:

	* psychiatry and mental health

mental health referral options

	* mental health crisis:
		* as per usual mental health patients

	* RCH mental Health services for children up to 15yrs - Flemington, Sunshine and Hoppers Crossing ph: 1800 44 55 11</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Sep 2015 08:51:10 +0000</pubDate>
        </item>
        <item>
            <title>ataxia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ataxia</link>
            <description>ataxia

see also:

	* neurology
	* examination of cranial nerves
	* ataxia
	* stroke (CVA)
	* transient ischaemic attack (TIA)
	* vertigo - peripheral vs central

Introduction

	* ataxia is the inability to maintain motor coordination and this may be:
		*  gait - which could be unilateral disturbance
		*  speech
		*  ocular movements

	* normal balance requires at least two of the following sensory inputs to be functional:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 16 Sep 2018 09:38:19 +0000</pubDate>
        </item>
        <item>
            <title>atenolol (Tenormin)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=atenolol</link>
            <description>atenolol (Tenormin)

see also beta adrenergic blockers, hypertension, angina

	* MIMS

Introduction:

	* atenolol is a “cardioselective” beta adrenergic blocker with primarily beta 1 blockade but with some beta 2 blockade (hence use with care in asthmatics).
	* half life ~6h
	* duration of action ~24h</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Feb 2009 10:06:08 +0000</pubDate>
        </item>
        <item>
            <title>atherosclerosis and primary prevention</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=atherosclerosis</link>
            <description>atherosclerosis and primary prevention

see also:

	* cardiology
	* ischaemic heart disease (IHD)
	* risk factors and molecular genetics of atherosclerosis
	* pathophysiology of atherosclerosis



Source: JAHA 2026: Sex Differences in Age of Onset of Premature Cardiovascular Disease and Subtypes: The Coronary Artery Risk Development in Young Adults Study via &lt;https://www.sciencealert.com/study-reveals-a-turning-point-when-mens-heart-attack-risk-accelerates&gt;

Primary prevention:

dental care

	* …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Mar 2026 21:41:04 +0000</pubDate>
        </item>
        <item>
            <title>atherosclerosis - pathophysiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=atherosclerosis_pathophysiology</link>
            <description>atherosclerosis - pathophysiology

see also:

	* atherosclerosis and primary prevention; 
	* risk factors and molecular genetics of atherosclerosis

Pathophysiology:

	* in 2017, the inflammation hypothesis of atherothrombosis was proven with the 10 000-participant CANTOS (Canakinumab Anti-Inflammatory Thrombosis Outcomes Study) in which targeting IL-1b significantly lowered major cardiovascular events rates in the absence of any effect on cholesterol, blood pressure, or coagulation, and the mag…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 07 Jan 2026 09:05:27 +0000</pubDate>
        </item>
        <item>
            <title>atherosclerosis - risk factors and molecular genetics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=atherosclerosis_riskfactors</link>
            <description>atherosclerosis - risk factors and molecular genetics

see also:

	*  atherosclerosis and primary prevention; 
	*  pathophysiology of atherosclerosis

Risk Factors:

major risk factors:

chronic low grade inflammation

	*  the increase in risk per SD of inflammation measured either by hsCRP (high-sensitivity C-reactive protein) or IL-6 consistently exceeded that of a 1-SD increase in cholesterol or blood pressure</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 02:13:00 +0000</pubDate>
        </item>
        <item>
            <title>Sydney funnel web spider bites (Atraxis)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=atraxis</link>
            <description>Sydney funnel web spider bites (Atraxis)

see also:

	* toxinology
	* redback spider bites
	* spider bites in Australia
	* &lt;http://www.news.com.au/lifestyle/health/health-problems/i-felt-something-crawl-up-my-leg-this-woman-survived-every-aussies-worst-nightmare/news-story/d2a0358c13574494610ceeb1debaf04d&gt;
	* NSW Health guideline

Introduction

	* Australian funnel-web spiders belong to two genera of the family Hexathelidae: Hadronyche and Atrax. 
	* They are medium to large spiders; generally b…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 19 Feb 2021 00:35:13 +0000</pubDate>
        </item>
        <item>
            <title>atropine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=atropine</link>
            <description>atropine

see also anti-muscarinic anticholinergic agents

History:

	* alkaloid from the deadly nightshade (Atropa belladonna) &amp; in Jimson weed plant (Datura stramonium) &amp; other of genus Solanaceae;
	* Was used by ancient Hindus, Roman Empire, etc. as poison;
	* Used by Italian women to dilate eyes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Aug 2011 11:36:44 +0000</pubDate>
        </item>
        <item>
            <title>autacoids</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=autacoids</link>
            <description>autacoids

see also physiology main index

introduction:

	* autacoids are substances with diverse physiological &amp; pharmacological activities which are grouped together mainly as they participate in physiological &amp; pathophysiological responses to injury.
	* they cannot be classed as hormones or neurotransmitters &amp; as they usually have a brief lifetime &amp; act near their sites of synthesis, they are often described as local hormones, but true hormones reach their site of action via the bloodstream …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Sep 2013 08:41:52 +0000</pubDate>
        </item>
        <item>
            <title>Help for Authors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=authors_help</link>
            <description>Help for Authors

Only authorised users are permitted to update or create Wiki pages.

If you wish to become an author

	* first register yourself as a user on the wiki by clicking on the Login button at top left then click on Register 
	* please contact the webmaster via email Gary.Ayton at wh.org.au so he can grant you author status as default registered users can still only just have read access until they are approved to be authors - ie. you must give evidence that you are an ACEM fellow or …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 22 Apr 2010 02:11:48 +0000</pubDate>
        </item>
        <item>
            <title>autism spectrum disorder (ASD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=autism</link>
            <description>autism spectrum disorder (ASD)

see also:

	* Asperger's syndrome
	* attention deficit hyperactivity disorder (ADHD)
	* comparison of developmental disorders affecting social development

introduction

	* autism spectrum disorder (ASD) is a range of severities of childhood development disorders, in particular, deficits in non-verbal communication skills and impaired social interaction</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Sep 2012 05:34:51 +0000</pubDate>
        </item>
        <item>
            <title>autoimmune disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=autoimmunity</link>
            <description>autoimmune disease

see also:

	* adaptive immunity
	* immunology

Introduction

	* most autoimmune diseases are due to cell-type selective cell destruction due to antibodies produced from B cells binding those cells and making them a target for T cell mediated destruction
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 28 Aug 2025 23:00:53 +0000</pubDate>
        </item>
        <item>
            <title>plain abdominal X-ray (AXR)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=axr</link>
            <description>plain abdominal X-ray (AXR)

see also:

	* radiology
	* the chest X-ray (CXR)
	* the patient with acute abdominal pain in the ED

introduction

	* plain AXR is generally avoided unless there is a specific indication which outweighs the radiation risks given the radiation dose is equivalent to ~ 20 chest XRays
	* when looking for</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2025 06:49:31 +0000</pubDate>
        </item>
        <item>
            <title>azathioprine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=azathioprine</link>
            <description>azathioprine

see also:

	* pharmacology main index
	* immunosuppressants
	* Crohn's disease

introduction

	* azathioprine (Imuran) is a imidazole 6-mercaptupurine derivative immunosuppressant.

uses

	* Crohn's disease
	* transplant recipients
	* severe RA
	* systemic lupus erythematosus (SLE)
	* dermatomyositis
	* autoimmune chronic active hepatitis
	* pemphigus vulgaris
	* polyarteritis nodosa (PAN)
	* autoimmune haemolytic anaemia
	* chronic refractory ITP

adverse effects</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Apr 2011 04:01:31 +0000</pubDate>
        </item>
        <item>
            <title>azithromycin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=azithromycin</link>
            <description>azithromycin

see also:

	* macrolide antibiotics

introduction

	* azithromycin is a broad spectrum antibiotic which acts by inhibition of protein synthesis in bacteria by binding to the 50S ribosomal subunit and preventing translocation of peptides.
	* it is the first of a class of antibiotics designated chemically as azalides, a subclass of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 06 Jun 2015 07:58:28 +0000</pubDate>
        </item>
        <item>
            <title>back pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=backpain</link>
            <description>back pain in the ED

see also:

	* analgesics, drug dependent patients
	* orthopaedics in the ED
	* abdominal pain in the ED
	* the lumbosacral spine Xray
	* RANZCR Choosing Wisely for radiology investigations for low back pain 
		*  NB. these guidelines may apply to primary care cohorts but may NOT apply to ED cohorts where there are higher pre-test probabilities of serious pathology!

	*  Safer Care Vic: patient info sheet low back pain (pdf)

introduction:

	* back pain can be a very deceptiv…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:41:29 +0000</pubDate>
        </item>
        <item>
            <title>The adolescent with back pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=backpain_adol</link>
            <description>The adolescent with back pain in the ED

first read: back pain in the ED

see also: orthopaedics in the ED; paediatric emergency medicine

Adolescent with back pain

aetiology:

	* traumatic:
		* muscle strain or tendinitis
		* crush fracture Tx vertebrae from compressive injury or hyperflexion injury (eg. fall from pushbike over handlebars onto head or fall from height onto feet)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 20 Dec 2016 06:23:07 +0000</pubDate>
        </item>
        <item>
            <title>The adult with back pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=backpain_adult</link>
            <description>The adult with back pain in the ED

first read back pain in the ED

see also:

	* orthopaedics in the ED
	* analgesics
	* sensory &amp; motor testing including dermatomes, myotomes, reflexes, coordination &amp; balance
	* groin pain
	* buttock pain
	* RANZCR Choosing Wisely for radiology investigations for low back pain 
		*  NB. these guidelines may apply to primary care cohorts but may NOT apply to ED cohorts where there are higher pre-test probabilities of serious pathology!

	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:40:51 +0000</pubDate>
        </item>
        <item>
            <title>The elderly patient with back pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=backpain_elderly</link>
            <description>The elderly patient with back pain in the ED

first read:  back pain in the ED

see also orthopaedics in the ED

Mx of the elderly:

aetiology:

	* pyelonephritis
	* renal colic
	* abdominal aortic aneurysm (AAA)
	* dissection thoracic aorta (usually have chest pain =&gt; back with PH hypertension)
	* crush fracture Tx/Lx spine
	* metastatic pathologic fractures</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Nov 2008 01:40:30 +0000</pubDate>
        </item>
        <item>
            <title>mechanical musculo-skeletal lower back pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=backpain_mechanical</link>
            <description>mechanical musculo-skeletal lower back pain

see also:

	* sciatica
	* back pain in the ED
	* spondylolisthesis

other references

	* avoiding over-arching of lumbar spine to prevent postural low back pain</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 28 Jan 2016 14:16:23 +0000</pubDate>
        </item>
        <item>
            <title>acute thoracic back pain in the adult</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=backpain_thoracic_adult</link>
            <description>acute thoracic back pain in the adult

see also:

	* back pain in the ED
	* see also interscapular thoracic back pain

introduction:

	* back pain can be a very deceptive presentation, all too easily put down to muscle strain while missing potentially time critical diagnoses.
	* watch for red flags in the presentation and specifically search for and exclude the main differentials.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 23 Jul 2024 13:39:53 +0000</pubDate>
        </item>
        <item>
            <title>clinically important bacteria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bacteria</link>
            <description>clinically important bacteria

see also:

	* microbiology
	* aseptic non-touch technique (ANTT)
	* a brief taxonomy of bacteria
	* antibiotics
	* taxonomy of bacteria on wikipedia

clinical classification of bacteria

Gram -ve rods:

	* mainly belong to Enterobacteriaceae family &amp; are non-fastidious, facultative anaerobes with fermentative metabolism, oxidase negative, bile tolerant, &amp; if motile then have peritrichous flagella</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 28 Sep 2025 07:43:28 +0000</pubDate>
        </item>
        <item>
            <title>carbapenemase producing or resistant enterobacteriaceae (CPE/CRE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bacteria_cpe</link>
            <description>carbapenemase producing or resistant enterobacteriaceae (CPE/CRE)

see also:

	* clinically important bacteria

introduction

	* enterobacteriaceae are fermentative, non-fastidious, oxidase negative, facultative anaerobic, Gram -ve rods
	* since 2012, an increasing number of KPC-producing Klebsiella pneumoniae have been identified in Victoria</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 06 Jan 2016 07:35:52 +0000</pubDate>
        </item>
        <item>
            <title>bacterial defence mechanisms</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bacteria_defences</link>
            <description>bacterial defence mechanisms

see also:

	* clinically important bacteria

Introduction

Bacterial cell wall

	* bacterial cell walls are made of peptidoglycans made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids, and have the following functions:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Jan 2025 09:26:25 +0000</pubDate>
        </item>
        <item>
            <title>a brief taxonomy of bacteria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bacteria_taxonomy</link>
            <description>a brief taxonomy of bacteria

see also:

	* clinically important bacteria
	* bacterial defence mechanisms

introduction

	* bacteria were the earliest forms of prokaryotes (organisms that lack a cell nucleus), it is thought the first to evolve were the Gram +ve bacteria (these do not have a bacterial outer membrane), then the Gram -ves (which do have an outer membrane).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Dec 2023 01:55:17 +0000</pubDate>
        </item>
        <item>
            <title>barbiturates</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=barbiturates</link>
            <description>barbiturates

see also sedatives, hypnotics and anxiolytics, anticonvulsants, induction agents for anaesthesia, pharmacology main index

Introduction:

	* Introduced in 1903. 
	* Meprobomate was introduced in 1954 as a nonbarbiturate sedative lacking the disadvantages of the older drugs. It turned out to have more similarities than differences from barbiturates.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Mar 2009 05:28:30 +0000</pubDate>
        </item>
        <item>
            <title>the bariatric patient in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bariatric_pt</link>
            <description>the bariatric patient in the ED

see also:

	* obesity and weight management
	* the obese patient in the ED
	* all major Australian hospitals should have bariatric facilities and procedures to safely manage these patients, although they will have restrictions on capacity for radiologic imaging
	* WH procedures (intranet only):</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 19 Aug 2019 07:59:08 +0000</pubDate>
        </item>
        <item>
            <title>Barmah Forest virus (BFV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=barmahforestvirus</link>
            <description>Barmah Forest virus (BFV)

see also:

	* zoonoses
	* Ross River virus (RRV)
	* Murray Valley encephalitis (MVE)
	* Japanese encephalitis virus (JEV)
	* &lt;https://www.health.vic.gov.au/infectious-diseases/barmah-forest-virus-disease&gt;

Introduction

	* a mosquito-borne viral infection which causes epidemic polyarthritis with very similar clinical features to Ross River virus (RRV)
	* a member of the alphavirus genus of viruses which also includes Ross River, Sindbis and Chikungunya virus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 09 Dec 2022 00:10:26 +0000</pubDate>
        </item>
        <item>
            <title>Bartonella</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bartonella</link>
            <description>Bartonella

see also:

	* cat scratch disease

Introduction

	* Bartonella is a genus of Gram negative facultative intracellular bacteria
	* Bartonella species are transmitted to humans and other mammals (which are its main reservoirs) by vectors such as ticks, fleas, sand flies, and mosquitoes.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 17 Jul 2020 09:00:04 +0000</pubDate>
        </item>
        <item>
            <title>basophilopenia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=basophilopenia</link>
            <description>basophilopenia

see also:

	* full blood examination (FBE)
	* neutropenia
	* eosinophilia
	* eosinopenia

aetiology

	* acute infection or haemorrhage
	* anaphylaxis, urticaria, drug hypersensitivity
	* corticosteroids
	* cytotoxic agents
	* thyroid hormones
	* ionizing radiation
	* hyperthyroidism
	* neoplasia / cancer / tumours
	* ovulation
	* congenital absence</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Aug 2013 14:28:52 +0000</pubDate>
        </item>
        <item>
            <title>brain-derived neurotrophic factor (BDNF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bdnf</link>
            <description>brain-derived neurotrophic factor (BDNF)

see also:

	* neurotrophins
	* BDNF on wikipedia

introduction

	* a member of the neurotrophin neural growth factor family and is a secreted protein
	* it helps to support the survival of existing neurons, and encourage the growth and differentiation of new neurons and synapses</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 22 Feb 2014 00:40:58 +0000</pubDate>
        </item>
        <item>
            <title>bed bugs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bedbugs</link>
            <description>bed bugs

see also:

	* insect bites and stings
	* human louse / lice
	* wikipedia
	* &lt;http://www.cdc.gov/parasites/bedbugs/faqs.html&gt;
	* &lt;https://www.youtube.com/watch?v=2JAOTJxYqh8&gt;

introduction

	* bed bugs (Cimex lectularius) are a small (1-7mm), slim, flat, parasitic insects that feed solely on the blood of humans and animals while they sleep and are a global issue, particularly in tourist accommodation rooms, and whilst annoying, fortunately, are not known to transmit disease although peo…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 May 2025 06:40:17 +0000</pubDate>
        </item>
        <item>
            <title>ED bedside ultrasound</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bedsideuss</link>
            <description>ED bedside ultrasound

see also:

	* ACEM policy - bedside ultrasound (pdf)
	* ACEM guideline - Minimum Criteria for Ultrasound Workshop (pdf)
	* Australian Institute of Ultrasound
	* Ultrasound Training Solutions
	* Australian School of Medical Imaging (ASMI)
		* est. in 2005 evolving from the Canberra School of Sonography which was formed in 1999.

	* Emed Ultrasound

Principles of medical USS

	* medical US on wikipedia
	* basics of ultrasound
	* ultrasound image production
	* ultrasound imag…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Feb 2024 00:29:58 +0000</pubDate>
        </item>
        <item>
            <title>benzodiazepines</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=benzodiazepines</link>
            <description>benzodiazepines

see also sedatives, hypnotics and anxiolytics, anticonvulsants, diazepam, midazolam, clonazepam, benzodiazepine antagonists eg. flumazenil

Overview:

	* 1st used in 1961, &amp; now have displaced barbiturates as sedative/hypnotics due to the remarkably low capacity to produce fatal CNS depression in OD &amp; the main ones marketed are less sedative for the same anxiolytic effect.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 20 Apr 2009 05:51:17 +0000</pubDate>
        </item>
        <item>
            <title>benzodiazepine antagonists</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=benzodiazepine_antagonists</link>
            <description>benzodiazepine antagonists

see also benzodiazepines, toxicology

Adverse effects of benzodiazepine antagonists

	* may ppt withdrawal seizures -&gt; titrate dose &amp; Rx 5mg IV midaz/diazepam;
	* may remove protective anticonvulsant effect of benzodiazepines in multiple OD;
	* re-sedation from overdose as duration of action is only 45-105min.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Aug 2011 11:19:16 +0000</pubDate>
        </item>
        <item>
            <title>benztropine / benzatropine (Cogentin)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=benztropine</link>
            <description>benztropine / benzatropine (Cogentin)

see also:

	* extrapyramidal reactions such as oculogyric crisis, dystonic reactions, akathisia

introduction

	* benztropine is a compound with parts of atropine and parts of diphenhydramine
	* it thus has anticholinergic properties and antihistamine properties
	* it is mainly used parenterally in the emergent Rx of acute</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 08 Oct 2022 02:11:17 +0000</pubDate>
        </item>
        <item>
            <title>benzyl penicillin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=benzylpenicillin</link>
            <description>benzyl penicillin

see also:

	* penicillins

introduction

	* benzyl penicillin is a narrow spectrum penicillin with activity against:
		* Gram +ves such as most Streptococcal species but not Staph.
		* Neisseria (meningococcus, gonococcus)
		* enterococci


preparation and administraion</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 05:02:06 +0000</pubDate>
        </item>
        <item>
            <title>beryllium oxide inhalation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=berylium_oxide</link>
            <description>beryllium oxide inhalation

see also:

	* toxicology
	* pneumonitis

Introduction

	* beryllium oxide (BeO) is an odorless electrical insulator found on magnetrons of microwaves and other devices
	* sintered beryllium oxide is a very stable ceramic
	* used as a structural ceramic for high-performance microwave devices, vacuum tubes, cavity magnetrons, and gas lasers.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 03 Aug 2024 13:17:08 +0000</pubDate>
        </item>
        <item>
            <title>beta 2 adrenergic agonists</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=beta2agonists</link>
            <description>beta 2 adrenergic agonists

see also:

	* asthma
	* sympathomimetics

introduction

	* agents with primary beta 2 adrenergic agonist activity form the 1st line medications for acute asthma exacerbations owing to their potent bronchodilator effects.
	* they are also used in premature labour to inhibit uterine contractions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Dec 2014 04:24:10 +0000</pubDate>
        </item>
        <item>
            <title>beta adrenergic blockers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=betablockers</link>
            <description>beta adrenergic blockers

see also:

	* beta blocker overdose
	* history of beta blockers
	* cardiology
	* pharmacology main index
	* sympathomimetics
	* propranolol
	* metoprolol
	* atenolol (Tenormin)
	* esmolol
	* sotalol
	* hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers

introduction

	* beta blockers are used for many therapeutic effects including lowering blood pressure, slowing the heart rate, reducing mortality after acute myocardial infarction (AMI/STEMI/NSTE…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 02:54:34 +0000</pubDate>
        </item>
        <item>
            <title>blue-green algae (BGA) toxins in waterways</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bgatoxins</link>
            <description>blue-green algae (BGA) toxins in waterways

see also:

	* toxinology
	* Victorian BGA bloom outbreaks updates online
	* &lt;https://www.cdc.gov/habs/materials/factsheet-cyanobacterial-habs.html&gt;
	* dinoflagellate blooms can also produce toxins
		*  Karenia mikimotoi, Karenia cristata and other Karenia sp brown blooms can cause coughing, eye irritation, etc to humans on beaches or swimming as well as death to sea life</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Nov 2025 22:09:38 +0000</pubDate>
        </item>
        <item>
            <title>rupture of biceps tendon</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=biceps_rupture</link>
            <description>rupture of biceps tendon

introduction

	* there are 3 tendons of the biceps muscle:
		* 2 proximal:
			* long head
			* short head (rarely ruptured)

		* 1 distal

	* tendon rupture usually occurs during a specific traumatic event that causes sudden pain, a</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Dec 2013 06:12:37 +0000</pubDate>
        </item>
        <item>
            <title>biliary colic</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=biliary_colic</link>
            <description>biliary colic

see also:

	* the patient with acute abdominal pain in the ED
	* cholelithiasis (gallstones)
	* gallbladder polyps

	* at Western Health, these patients are generally suitable for admission to SSU (EOU) however all patients presenting with symptomatic known or suspected biliary disease (or those with stones &gt; 2cm) should be referred to surgical registrar to ensure timely surgical Mx and prevention of complicated disease</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 31 Mar 2026 06:19:20 +0000</pubDate>
        </item>
        <item>
            <title>bio-accumulations and long term health</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bioaccumulations</link>
            <description>bio-accumulations and long term health

see also:

	* foods that may be toxic or bad for you
	* air pollution and health risks

Introduction

	* long term accumulation of potentially biologically active substances in the body is an increasing concern and is becoming more recognized as a major health threat not only to humans, but also other animals</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 01 Aug 2025 01:39:14 +0000</pubDate>
        </item>
        <item>
            <title>bions - non-living &quot;nanobacteria&quot; / nanoparticles</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bions</link>
            <description>bions - non-living &quot;nanobacteria&quot; / nanoparticles

see also:

	* clinically important bacteria

introduction

	* for decades the so-called nanobacteria have tantalised the scientific world as possible new types of life forms as they are about 1/10th size of bacteria and thus should not be able to be big enough to contain cellular elements such as DNA, RNA, organelles, but they behave life bacteria in that they are self-propagating and can divide and form branches</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2025 07:37:51 +0000</pubDate>
        </item>
        <item>
            <title>bio-weapons / biological weapons</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bio_weapons</link>
            <description>bio-weapons / biological weapons

see also:

	* toxicology
	* polonium poisoning
	* nerve agents / nerve gases / CBR weapons

Introduction

	* biological weapons are internationally banned, nevertheless some states occasionally utilize them to kill opponents such as traitors (poisoning is often a slow and painful death) or as an agent of terrorism.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 Sep 2020 03:30:54 +0000</pubDate>
        </item>
        <item>
            <title>bipolar disorder</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bipolar_disorder</link>
            <description>bipolar disorder

see also psychiatry and mental health; anti-psychotic medications;

Introduction

	* bipolar disorder is characterised by episodic depressions and elevations of mood
		* bipolar I involves manic symptoms which last for at least a week and are severe enough to markedly impair functioning or require hospitalisation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 01 May 2009 00:05:32 +0000</pubDate>
        </item>
        <item>
            <title>bird flu / H5N1 / HPAI</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bird_flu</link>
            <description>bird flu / H5N1 / HPAI

see also:

	* influenza
	* pandemics - influenza, coronavirus, Ebola

Introduction

	* of the influenza viruses, only type A influenza viruses infect birds, and all known subtypes can do so.
			* 15 subtypes of influenza virus are known to infect birds, thus providing an extensive reservoir of influenza viruses potentially circulating in bird populations. Migratory waterfowl, esp. wild ducks, are the natural reservoir of avian influenza viruses, and these birds are the mo…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 May 2025 00:53:17 +0000</pubDate>
        </item>
        <item>
            <title>bisphenols (Bisphenol A (BPA), etc)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bisphenols</link>
            <description>bisphenols (Bisphenol A (BPA), etc)

see also:

	* phthalates
	* Perfluoroalkyl and polyfluoroalkyl substances (PFAS) including PFOA, PFOS, GenX, Teflon
	* foods that may be toxic or bad for you
	* endocrine disrupting chemicals (EDCs)

Introduction

	* these are commonly used chemicals 
	* BPA and similar are used in the lining of some food and beverage packaging to protect food from contamination and extend shelf life</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Apr 2026 01:03:44 +0000</pubDate>
        </item>
        <item>
            <title>bisphosphonates</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bisphosphonates</link>
            <description>bisphosphonates

see also:

	*  osteoporosis; 
	*  hypercalcaemia; 
	*  bone physiology

Introduction

	* bisphosphonates inhibit the resorption of bone by osteoclasts and may have an effect on osteoblasts. They are structurally similar to pyrophosphate, a normal product of human metabolism. This structure gives the drugs a high affinity for bone and they probably remain in bone for many years.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Jun 2025 20:21:31 +0000</pubDate>
        </item>
        <item>
            <title>assessing major bleeding risk on anticoagulants</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bleedingrisk</link>
            <description>assessing major bleeding risk on anticoagulants

see also:

	* atrial fibrillation
	* anticoagulants

HAS-BLED

	* originally derived from the Euro Heart survey evaluating risk of hemorrhage in patients with atrial fibrillation using warfarin
	* Score 1 point for each:
		*  hypertension if either uncontrolled or &gt; 160mmHgsystolic</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Jan 2018 00:49:43 +0000</pubDate>
        </item>
        <item>
            <title>blepharitis / dry eyes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=blepharitis</link>
            <description>blepharitis / dry eyes

see also:

	* dermatology
	* ophthalmology
	* Sjögren's syndrome (SS)
	* facial rashes

blepharitis

	* blepharitis is inflammation of the eyelids which is the main cause of dry eyes accounting for over 80% of cases
	* anterior blepharitis involves the skin, eyelashes and lash follicles</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Jun 2025 05:31:52 +0000</pubDate>
        </item>
        <item>
            <title>blood cultures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=blood_culture</link>
            <description>blood cultures

see also:

	* sepsis / septicaemia
	* infective endocarditis (including SBE)

introduction

	* patients with possible sepsis / septicaemia or infective endocarditis (including SBE) generally should have at least 2 sets of blood cultures taken (3 sets for suspected endocarditis), and preferably before commencing iv antibiotics
	* blood cultures can be taken from newly placed iv cannulae in the ED as long as the usual sterile technique is used</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Oct 2013 04:48:20 +0000</pubDate>
        </item>
        <item>
            <title>the blood donor who collapses</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=blood_donor</link>
            <description>the blood donor who collapses

see also:

	* syncope / near syncope

Introduction

	* by far the most common cause of syncope / near syncope or near syncope in a person who has just donated blood is a vasovagal syncope
	* HOWEVER, there are other potentially fatal causes which need to be considered, especially if it is a plasma donation and RBC's are separated from the plasma by apheresis and transfused back into the donor</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Aug 2019 00:38:44 +0000</pubDate>
        </item>
        <item>
            <title>massive blood transfusions</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=blood_massive</link>
            <description>massive blood transfusions

see also:

	* blood product transfusions
	* massive blood transfusion procedure (MTP)
	* Aust Nat. Blood Authority 2011 Guidelines (pdf)
	* Western Health Blood Products resource page

introduction

	* many health services have created a massive transfusion protocol (MTP) to help expedite timely and appropriate administration of blood and adjuncts to patients in need of massive blood transfusions.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Aug 2018 07:33:16 +0000</pubDate>
        </item>
        <item>
            <title>massive blood transfusion procedure (MTP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=blood_mtp</link>
            <description>massive blood transfusion procedure (MTP)

see also:

	* massive blood transfusions
	* Western Health - very detailed massive transfusion protocol (docx) - intranet only
	* WH emergency blood management plan (pdf) - intranet only 
	* WH Critical bleeding and massive transfusion - intranet only

criteria for activating MTP

	* actual or anticipated 4 units RBCs within 4 hours, + haemodynamically unstable, +/- anticipated ongoing bleeding, or,
	* severe thoracic, abdominal, pelvic or multiple long…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 04 Apr 2019 21:25:32 +0000</pubDate>
        </item>
        <item>
            <title>blood product transfusions</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=blood_transfusion</link>
            <description>blood product transfusions

see also:

	* blood_groups
	* haematology
	* massive blood transfusions
	* anaemia
	* the blood donor who collapses
	* USC 2008 conference video - strategies and evidence for managing the patient requiring massive transfusion for acute hemorrhage - subscription required
	* Western Health pretransfusion testing procedure (docx)
	* Western Health blood transfusion reaction form (docx) - intranet only
	* Western Health Blood Products resource page

	* as of 2023, the fol…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Mar 2023 05:44:41 +0000</pubDate>
        </item>
        <item>
            <title>the patient with acute blurred vision or visual loss / blindness</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=blurred_vision</link>
            <description>the patient with acute blurred vision or visual loss / blindness

see also:

	* ophthalmology
	* Eye injuries
	* diplopia / double vision
	* color blindness / color vision deficiency

introduction

	* acute non-traumatic blurred vision is a relatively common presentation to ED
	* patients may use the term blurred vision to cover a number of different symptoms such as:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 28 Mar 2019 23:25:29 +0000</pubDate>
        </item>
        <item>
            <title>bone marrow transplant (BMT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bmtransplant</link>
            <description>bone marrow transplant (BMT)

see also:

	* oncology
	* lymphoma
	* leukaemia
	* NSW patient information booklet on autologous BMT (pdf)
	* EVIQ.org: Autologous conditioning protocol BEAM (carmustine etoposide cytarabine melphalan) prior to bone marrow transplantation

Introduction

	* a bone marrow transplant is usually done to allow the oncology team to use high dose chemotherapy to give a better chance of creating remission from lymphoma, multiple myeloma or leukaemia, as these high doses wil…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Jan 2020 10:04:05 +0000</pubDate>
        </item>
        <item>
            <title>bone physiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bone</link>
            <description>bone physiology

see also:

	* calcium
	* orthopaedics in the ED
	* osteoporosis

Bone:

	* special form of connective tissue made of collagenous matrix impregnated with mineral salts, esp. calcium phosphates;
	* mainly hydroxyapatite Ca10-x (H20)2x (PO4)6 (OH)2 =&gt; 20 x 3-7 nm crystals;
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 14 Feb 2026 12:33:27 +0000</pubDate>
        </item>
        <item>
            <title>pathologic processes involving bone</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bone_pathology</link>
            <description>pathologic processes involving bone

see also:

	* bone physiology
	* osteoporosis
	* osteomalacia
	* calcification
	* diffuse osteosclerosis:
		* hypervitaminosis D
		* hypoparathyroidism
		* Paget's disease of the bone - rare under 40 years age
		* myelofibrosis
		* sickle cell disease
		* leukaemia
		* flouride, lead or beryllium toxicity
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 22 Feb 2023 09:17:17 +0000</pubDate>
        </item>
        <item>
            <title>botulinum toxin (Botox)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=botox</link>
            <description>botulinum toxin (Botox)

see also:

	* pharmacology main index
	* botulism
	* Australian Prescriber April 2009 - Clinical use of botulinum toxin

approved clinical uses in Australia

	* blepharospasm
	* cervical dystonia (spasmodic torticollis)
	* dynamic equinus foot deformity associated with cerebral palsy in children two years or over
	* spasticity following</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Jun 2023 05:49:52 +0000</pubDate>
        </item>
        <item>
            <title>botulism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=botulism</link>
            <description>botulism

see also:

	* botulinum toxin (Botox)

Introduction

	* botulism is a potentially fatal condition caused by neurotoxic Clostridial toxins produced by Clostridium species, such as C. butyricum, C. baratii, and C. sporogenes

Botulinum neurotoxins (BoNT)

	* these neurotoxins are categorized into eight serotypes ranging from A to H.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Jun 2023 06:01:01 +0000</pubDate>
        </item>
        <item>
            <title>benign prostatic hyperplasia (BPH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bph</link>
            <description>benign prostatic hyperplasia (BPH)

see also:

	* prostate cancer
	* urology
	* prostate specific antigen (PSA)
	* lower urinary tract symptoms (LUTS) in men
	* AUA guideline on Mx BPH (pdf)

introduction

	* BPH is an extremely common disorder of men over aged 50 years
	* histologic evidence is present in 20% of men at age 40 years, increasing to 70% by age 60 and 90% by age 80</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Apr 2018 04:46:25 +0000</pubDate>
        </item>
        <item>
            <title>Behavioural and Psychological Symptoms of Dementia (BPSD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bpsd</link>
            <description>Behavioural and Psychological Symptoms of Dementia (BPSD)

see also:

	* dementia
	* managing violence or the aggressive patient in the ED
	* Assessment and Management of People with Behavioural and Psychological Symptoms of Dementia (BPSD): A Handbook for NSW Health Clinicians

introduction

	*  BPSD is a collection of observed behaviours and psychological symptoms that tend to occur together in a person with dementia
	* BPSD typically presents in the later stages of dementia, with 60–90% of pe…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 21 Oct 2022 21:55:17 +0000</pubDate>
        </item>
        <item>
            <title>bradycardia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bradycardia</link>
            <description>bradycardia

see also:

	* ecg_avblock
	* cardiac arrhythmias

introduction

	* slow heart rate may be due to either:
		* sinus bradycardia (P waves present and are related to QRS complexes)
		* 2nd degree AV node block (P waves present but not always resulting in a QRS complex and thus rhythm may be irregular)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:04:30 +0000</pubDate>
        </item>
        <item>
            <title>Bradykinin and kinin physiology and pharmacology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bradykinin</link>
            <description>Bradykinin and kinin physiology and pharmacology

see also autacoids

Introduction:

	* IV injection of urine produced hypotension which lead to the discovery of kallikrein (“pancreas”) 1937 &amp; that this generated an active substance kallidin in 1948 which was shown to be a decapeptide (1961? - bradykinin with added lysine) cleaved from a plasma alpha2 globulin kallidinogen in 1970 later known as LMW kininogen as another plasma alpha2 globulin HMW kininogen is cleaved by kallikrein (&amp; some serine…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Aug 2010 04:35:09 +0000</pubDate>
        </item>
        <item>
            <title>the brain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=brain</link>
            <description>the brain

see also:

	* brain evolution and development
	* cerebrospinal fluid (CSF)
	* stroke (CVA)
	* neurology
	* consciousness
	* memory
	* speech
	* modelling the brain:
		*  Dec 2023: Uni of Cambridge, UK, announces by using their new concept 3D “spatially embedded recurrent neural networks” (seRNNs) they have created a self-organizing, artificially intelligent system that uses the same tricks as the human brain to solve specific tasks. The seRNNs converged on structural and functional fe…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 22 Aug 2025 09:13:15 +0000</pubDate>
        </item>
        <item>
            <title>brain evolution and development</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=brain_development</link>
            <description>brain evolution and development

see also:

	* the brain
	* cerebrospinal fluid (CSF)
	* consciousness

Introduction

	* in humans, the brain is the most expensive organ in the body requiring 20% of our energy, 75% of the human brain is neocortex
	* complex reasoning arises from a combination of:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Oct 2023 01:47:25 +0000</pubDate>
        </item>
        <item>
            <title>breath odours</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=breath_odours</link>
            <description>breath odours

see also:

	* diabetic ketoacidosis (DKA)

Introduction

	* a patient's breath odour may add clues to diagnosis of clinical conditions

ketotic

	* any cause of ketosis such as:
		*  diabetic ketoacidosis (DKA)
		*  alcoholic ketoacidosis
		*  starvation ketoacidosis


other fruity odours</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Sep 2023 10:54:25 +0000</pubDate>
        </item>
        <item>
            <title>brexpiprazole (Rexulti)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=brexpiprazole</link>
            <description>brexpiprazole (Rexulti)

see also:

	* anti-psychotic medications

Introduction

	* an atypical anti-psychotic medication
	* listed on Aust. PBS in late 2017 for Rx of schizophrenia, with the advantage of less weight gain or diabetic effects

Special precautions

	* hypersensitivity to brexpiprazole</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 01 Oct 2017 11:51:00 +0000</pubDate>
        </item>
        <item>
            <title>bronchiectasis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bronchiectasis</link>
            <description>bronchiectasis

see also:

	* respiratory medicine
	* chronic bronchitis

introduction

	* defined by localized, irreversible dilation of part of the bronchial tree caused by destruction of the muscle and elastic tissue
	* bronchi are dilated, inflamed, and easily collapsible, resulting in airflow obstruction and impaired clearance of secretions.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Jan 2026 20:34:24 +0000</pubDate>
        </item>
        <item>
            <title>bronchiolitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bronchiolitis</link>
            <description>bronchiolitis

see also paediatric emergency medicine

	* RCH guideline - bronchiolitis
	* RCH guideline - ongoing Mx of bronchiolitis
	* NSW NETS - bronchiolitis (pdf)
	* Dr Andrew Tagg's video tutorial on croup and bronchiolitis

other resources

 *Cochrane review 2008 - nebulised 3% saline may significantly reduce length of stay and improve clinical severity scores in infants with acute viral bronchiolitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jan 2015 13:29:39 +0000</pubDate>
        </item>
        <item>
            <title>brucellosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=brucellosis</link>
            <description>brucellosis

see also:

	* the febrile returned traveller
	* clinically important bacteria
	* zoonoses
	* wikipedia

introduction

	* aka Bang's disease, Crimean fever, Gibraltar fever, Malta fever, Maltese fever, Mediterranean fever, rock fever, or undulant fever
	* a highly contagious zoonosis caused by ingestion of unsterilized milk or meat from infected animals or close contact with their secretions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Nov 2018 16:41:13 +0000</pubDate>
        </item>
        <item>
            <title>Budd-Chiari syndrome (BCS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=buddchiari</link>
            <description>Budd-Chiari syndrome (BCS)

see also:

	* splanchnic vein thrombosis (SVT)
	* liver function tests (LFTs)
	* hepatitis
	* World J Gastroenterol. 2007  Budd-Chiari syndrome: Etiology, pathogenesis and diagnosis

Introduction

	* Budd-Chiari syndrome is a congestive hepatopathy caused by blockage of hepatic veins which also causes raised portal venous pressure which may lead to portal hypertension, ascites, etc.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Jun 2021 07:12:40 +0000</pubDate>
        </item>
        <item>
            <title>bulbar palsy and pseudobulbar palsy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=bulbar_palsy</link>
            <description>bulbar palsy and pseudobulbar palsy

see also:

	* Cranial nerve examination
	* Neuropathies
	* motor neurone disease (MND)

Introduction

	* bulbar palsy is lower motor neuron weakness of the muscles innervated by the cranial nerves IX, X and XII, while pseudobulbar palsy is an upper motor neuronal weakness of these muscles</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Mar 2026 23:11:54 +0000</pubDate>
        </item>
        <item>
            <title>clinical burnout</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=burnout</link>
            <description>clinical burnout

see also:

	* stress
	* addressing burnout - four words you don't want to hear - it's just a job
	* are you a doctor or medical student and need to see a doctor confidentially?
		* see Vic Doctors Health Program

	* Anxiety Disorders Assoc. of Vic. (AdaVic): ph: 03-9853-8089
	* burnout - symptoms and management
	* Dr Pamela Wible 2017: What I have learned from 547 doctor suicides
	* Online scoring tool - Oldenburg Burnout Inventory
	* &lt;https://www.healthroundtable.org/Join-Us/T…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 20 Jul 2022 08:15:28 +0000</pubDate>
        </item>
        <item>
            <title>addressing burnout - four words you don't want to hear - it's just a job</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=burnout_itsjustajob</link>
            <description>addressing burnout - four words you don't want to hear - it's just a job

see also:

	* clinical burnout
	* stress
	* &lt;https://www.healthroundtable.org/Join-Us/Thought-Leadership/Addressing-Burnout&gt;

The following was taken from News.com.au article

these four words that may offend you, may also just save you

“WHAT do you do for a living?” the young man asked me.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 20 Jul 2022 08:15:16 +0000</pubDate>
        </item>
        <item>
            <title>burns</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=burns</link>
            <description>burns

see also:

	* Sage burns calculator
	* RCH guideline - burns in children
	* NSW NETS severe burns transfer guidelines (pdf)
	* NSW NETS severe burns service - models of care (pdf)
	* Sth Aust. RAH Burns Service - Detailed algorithmic burns Mx document 2009 (pdf) - very nice document indeed!
	* Vic. multiple burns casualties guidelines 2015
	* Victorian Burns Unit Management Guidelines
	* electrocution / electrical injury

Indications for transfer to a burns service

	* Vic. Major Trauma T…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 07 Sep 2025 07:30:49 +0000</pubDate>
        </item>
        <item>
            <title>Buruli ulcer / Bairnsdale ulcer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=buruli</link>
            <description>Buruli ulcer / Bairnsdale ulcer

see also:

	* mycobacteria

Introduction

	* a chronic ulcer caused by Mycobacterium ulcerans, which, in southern Victoria, is thought to be spread by the common backyard Australian mosquito, Aedes notoscriptus with the possum being the reservoir  in endemic areas which are mainly those that are or were swamp lands</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 17 Dec 2025 23:33:12 +0000</pubDate>
        </item>
        <item>
            <title>buttock pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=buttock_pain</link>
            <description>buttock pain

see also:

	* The adult with back pain in the ED

Introduction

	* buttock pain is not an uncommon presentation, it may be:
		*  isolated pain
		*  associated with back pain and sciatica
		*  associated with abdominal pain such as with abdominal aortic aneurysm (AAA)
		*  primarily only on walking - buttock claudication</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 12 Oct 2025 08:05:34 +0000</pubDate>
        </item>
        <item>
            <title>butyrophenone type antipsychotic agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=butyrophenones</link>
            <description>butyrophenone type antipsychotic agents

see also:

	* anti-psychotic medications

introduction

	* butyrophenone type antipsychotic agents include:
		* haloperidol
		* droperidol (Droleptan)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 May 2014 06:47:13 +0000</pubDate>
        </item>
        <item>
            <title>C-MAC</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c-mac</link>
            <description>C-MAC

	* Karl Storz video laryngoscope
	* Interchangeable blade system with screen recording to SD card
	* Flexible nasendoscope component for airway assessment
	* Hyperangulated “D-blade” for trauma intubations, anterior larynx, decreased mouth opening</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 19 Nov 2016 23:24:14 +0000</pubDate>
        </item>
        <item>
            <title>complement C3, C4 testing</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c3_4</link>
            <description>complement C3, C4 testing

see also:

	* arthritis - clinical patterns
	* glomerulonephritis (GN)

introduction

	* complement testing is useless for screening for cause of arthritis but is often used to monitor disease activity in patients with SLE
	* decreased levels of complement arise from immune-complex disorders such as:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Dec 2015 04:28:59 +0000</pubDate>
        </item>
        <item>
            <title>cachexia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cachexia</link>
            <description>cachexia

see also:

	* neoplasia / cancer / tumours
	* oncology

Introduction

	* “Most people with cancer die of cachexia instead of cancer”

IL-6 as mediator of brain dysfunction and cachexia in cancer patients

	* blocking IL-6 from binding to neurons in a part of the brain called the area postrema (AP) prevents cachexia in mice, this worked by either:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Aug 2025 04:07:17 +0000</pubDate>
        </item>
        <item>
            <title>caeruloplasmin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=caeruloplasmin</link>
            <description>caeruloplasmin

see also:

	* copper
	* Wilson's disease

Introduction

	* usual serum levels are 0.15-0.30 g/L

Raised serum levels

	* may be due to:
		*  acute phase response
		*  liver disease
		*  pregnancy
		*  oestrogen Rx


Low serum levels

	* may be due to:
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 18 Aug 2020 07:45:34 +0000</pubDate>
        </item>
        <item>
            <title>caffeine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=caffeine</link>
            <description>caffeine

see also:

	* methylxanthines
	* Wikipedia for a good article on caffeine.

introduction

	* caffeine is a natural trimethylxanthine alkaloid which acts as a pesticide and perhaps herbicide and thus protects the growth of coffee bean plant and similar plants (tea, kola, cacao plants) which produce it.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Mar 2026 04:50:34 +0000</pubDate>
        </item>
        <item>
            <title>calcification</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=calcification</link>
            <description>calcification

see also:

	* calcium
	* urolithiasis / renal stones / renal calculi

introduction

	* it is possible that all extracellular mineralisation in the body occurs via secretion of membrane vesicles from cells which then form mineralo-organic nanoparticles called bions - non-living &quot;nanobacteria&quot; / nanoparticles which then can self-propagate</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2025 06:47:21 +0000</pubDate>
        </item>
        <item>
            <title>calcitonin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=calcitonin</link>
            <description>calcitonin

see also:

	* calcium
	* parathyroid hormone (PTH)
	* vitamin D

Introduction

Chemistry:

	* Calcitonin is a 34AA polypeptide (MW 3500) synthesised and secreted by the parafollicular (or clear cells) cells of the thyroid and in small amounts elsewhere:
	* “Calcitonin gene”</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 24 Sep 2009 07:29:23 +0000</pubDate>
        </item>
        <item>
            <title>calcium</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=calcium</link>
            <description>calcium

see also:

	* phosphate
	* magnesium
	* vitamin D
	* parathyroid hormone (PTH)
	* calcitonin
	* hypercalcaemia
	* hypocalcaemia
	* calcium gluconate
	* osteoporosis
	* bone physiology

iv calcium in the ED

	* intravenous calcium as either calcium chloride or calcium gluconate is occasionally required in the ED to treat:
		* severe hypocalcaemia
		* severe hyperkalaemia

	* calcium gluconate is generally preferred as it causes less tissue damage if inadvertently extravasated</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 24 Jul 2014 06:01:22 +0000</pubDate>
        </item>
        <item>
            <title>calcium channel blockers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=calciumblockers</link>
            <description>calcium channel blockers

see also:

	* calcium channels
	* calcium channel blocker overdose
	* historical perspective of calcium channel physiology and pharmacology
	* cardiology
	* pharmacology main index
	* anti-arrhythmic agents

	* excessive dosing of alpha adrenergic agonists may cause hypertensive crisis which may be fatal, and attempts to treat such alpha agonist crises with beta adrenergic blockers or calcium channel blockers may cause acute pulmonary oedema (APO) and thus these agents …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 19 Mar 2020 10:30:34 +0000</pubDate>
        </item>
        <item>
            <title>Calcium channels</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=calciumchannels</link>
            <description>Calcium channels

see also calcium channel blockers, calcium

Ca Channels:

Slow voltage-gated:

	* eg. via high [K]e or depolarising electrical stimuli;
	* consists of alpha1, alpha2, beta, gamma, delta subunits;
	* certain snail toxins from genus Conus &amp; Cd/Mn cations block a wide range of Ca channel subtypes;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 14 Sep 2008 23:56:18 +0000</pubDate>
        </item>
        <item>
            <title>calcium gluconate</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=calcium_gluconate</link>
            <description>calcium gluconate

see also:

	* hypocalcaemia
	* hyperkalaemia
	* calcium

	* 10ml ampoule of 10% calcium gluconate contains 2.2 mmoles of calcium ions

introduction

	* 10% calcium gluconate solution is the preferred parenteral form of calcium except in cardiac arrest situations when 10% calcium chloride is preferred as it delivers 3x as much elemental calcium</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Dec 2013 03:11:51 +0000</pubDate>
        </item>
        <item>
            <title>Campylobacter</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=campylobacter</link>
            <description>Campylobacter

see also:

	* gastroenteritis

summary of Rx

	* Campylobacter is a relatively common cause of enteritis and usually diagnosed on stool culture
	* most patients do not need specific Rx as it is usually self limiting
	* asymptomatic contacts do not need either stool cultures or treatment.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Feb 2009 00:47:03 +0000</pubDate>
        </item>
        <item>
            <title>candida fungal infection / thrush</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=candida</link>
            <description>candida fungal infection / thrush

see also:

	* fungi
	* antifungal agents

Introduction

	* Candida sp is a yeast and the main human pathogen in the Candida family has been C. albicans but in 2009, a new species, C. auris was discovered and this organism appears to be developing into a global threat for at risk critically ill hospitalised patients</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Feb 2026 00:12:14 +0000</pubDate>
        </item>
        <item>
            <title>cannabinoid hyperemesis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cannabinoid_hyperemesis</link>
            <description>cannabinoid hyperemesis

see also:

	* marijuana / cannabis / THC
	* &lt;http://lifeinthefastlane.com/therapeutic-showering/&gt;
	* St Luke's patient information sheet
	* &lt;https://www.forbes.com/sites/robertglatter/2016/12/30/syndrome-linked-to-smoking-weed-spikes-in-states-with-legalized-marijuana/#79c3de4d63d7&gt;

introduction

	* 1st identified as a syndrome in Australia in 2004
	* classically associated with relief from hot showers resulting in compulsive showers/bathing
	* cyclical every 2-3weeks
	…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 20 Aug 2024 09:52:06 +0000</pubDate>
        </item>
        <item>
            <title>community acquired pneumonia (CAP) in adults</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cap</link>
            <description>community acquired pneumonia (CAP) in adults

see also:

	* pneumonia
	* pneumococcus
	* Legionella (Legionaire's disease)
	* psittacosis
	* RCH guideline - paediatric pneumonia
	* AFTB lectures - community acquired pneumonia (CAP)

introduction

	* CAP means pneumonia acquired in the community and NOT following a period of recent hospitalisation where there would be a much higher risk of antibiotic resistant or different organisms causing the pneumonia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:48:57 +0000</pubDate>
        </item>
        <item>
            <title>carbamazepine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=carbamazepine</link>
            <description>carbamazepine

see also:

	* anticonvulsants
	* wikipedia
	* Consumer information (pdf)

overview

	* related to tricyclics, used as anticonvulsant since 1965 in UK and since 1974 in the US and marketed as Tegretol.
	* also used as a mood stabiliser in bipolar disorders, and for trigeminal neuralgia and other types of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Apr 2011 08:38:47 +0000</pubDate>
        </item>
        <item>
            <title>carbapenem antibiotics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=carbapenems</link>
            <description>carbapenem antibiotics

see also:

	* antibiotics

introduction

	* broad spectrum against many Gram +ves, -ves &amp; anaerobes
	* reserved for ICU use

imipenem

	* a derivative of thienamycin;
		* It is a potent broad spectrum antibiotic used for severe intra-abdominal sepsis or serious  infections with Enterobacteriaceae which produce inducible b-lactamase;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 May 2013 08:18:33 +0000</pubDate>
        </item>
        <item>
            <title>carbimazole</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=carbimazole</link>
            <description>carbimazole

see also:

	* hyperthyroidism
	* propylthiouracil

Introduction

	* carbimazole is the first line thionamide in almost all patients with hyperthyroidism needing Rx with an antithyroid medication as it results in a more rapid improvement in thyroid hormone levels, has less hepatotoxicity, and can be given once daily due to its longer half life</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 27 Jan 2020 06:19:35 +0000</pubDate>
        </item>
        <item>
            <title>Carbonic anhydrase inhibitors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=carbonic_anhydrase_inhib</link>
            <description>Carbonic anhydrase inhibitors

see also diuretics, glaucoma

Introduction

	* Carbonic anhydrase 1st discovered in RBC's (1930's), &amp; sulfanilimide-induced metab.acidosis shown to be inhib. of this enzyme.
	* Little used as diuretic but still for glaucoma &amp; prevention of ac. mountain sickness;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Oct 2008 07:24:32 +0000</pubDate>
        </item>
        <item>
            <title>carcinoid tumour</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=carcinoid</link>
            <description>carcinoid tumour

see also:

	* post-prandial diarrhoea

introduction

	* neuroendocrine tumour derived from primitive stem cells in the gut wall but can arise elsewhere
	* high potential for metastasis

clinical features

	* recurrent abdo pains
	* cutaneous flushing
	* malabsorption and</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Dec 2017 00:36:29 +0000</pubDate>
        </item>
        <item>
            <title>cardiac markers (troponin)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cardiac_markers</link>
            <description>cardiac markers (troponin)

see also:

	* acute myocardial infarction (AMI/STEMI/NSTEMI)
	* Mx of possible acute coronary syndrome without ST elevation (NSTEACS)
	* acute coronary syndromes


chart from wikipedia

troponin

	* see also troponin
	* troponin has now replaced CK-MB as the main marker for acute coronary events
	* there is still debate as to the appropriate timing of troponin levels - many use 4 hourly levels up to 12 hours post-onset of most severe pain episode, whilst others are ha…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 28 Mar 2020 01:43:00 +0000</pubDate>
        </item>
        <item>
            <title>who needs cardiac monitoring, and for how long?</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cardiac_monitoring</link>
            <description>who needs cardiac monitoring, and for how long?

see also:

	* cardiology

almost certainly need cardiac monitoring
condition    duration  possible cardiac chest pain    until 2nd trop is normal unless high risk features mandate further monitoring  hyperkalaemia    until K+ &lt; 6.5</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 02 Nov 2016 06:58:15 +0000</pubDate>
        </item>
        <item>
            <title>cardiac tamponade</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cardiac_tamponade</link>
            <description>cardiac tamponade

see also:

	* pericarditis
	* haemopericardium
	* trauma

introduction

	* accumulation of pericardial fluid under pressure results in impaired cardiac venous filling and resultant impaired cardiac output which may rapidly become life threatening unless relieved by therapeutic</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 24 Aug 2019 11:37:18 +0000</pubDate>
        </item>
        <item>
            <title>cardiogenic shock</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cardiogenic_shock</link>
            <description>cardiogenic shock

see also:

	* the shocked hypotensive patient
	* return of spontaneous circulation (ROSC) post-arrest
	* acute myocardial infarction (AMI/STEMI/NSTEMI)
	* cardiac tamponade
	* pulmonary embolism (PE)

Introduction

	* cardiogenic shock is shock due to a cardiac cause
	* it is said to be the most common cause of death in hospitalised patients

Aetiology

cardiomyopathic

	* ischaemic - especially, acute myocardial infarction (AMI/STEMI/NSTEMI)
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 22 Jul 2022 23:28:38 +0000</pubDate>
        </item>
        <item>
            <title>cardiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cardiology</link>
            <description>cardiology

see also:  Wiki Main index

	* choking / respiratory arrest / cardiac arrest / BLS / ALS / CPR
	*  Paediatric Resuscitation Drugs
	* the ECG
	* cardiac arrhythmias
	* anti-arrhythmic agents
	* cardiac conduction blocks
	* cardiac physiology
	* atherosclerosis and primary prevention
	* hyperlipidaemia
	* the adult with chest pain in the ED
	* who needs cardiac monitoring, and for how long?
	* ischaemic heart disease (IHD) or coronary artery disease (CAD)
	* acute coronary syndromes
	*…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 02 Aug 2025 11:22:14 +0000</pubDate>
        </item>
        <item>
            <title>cardiomyopathy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cardiomyopathy</link>
            <description>cardiomyopathy

see also:

	* cardiology

introduction

	* the term is usually reserved for conditions in which severe myocardial disease leads to cardiac failure
	* they can be classified as:
		* “primary” or “intrinsic”
			* condition is primarily due to the cardiac muscle, although many of thee conditions now have identifiable extrinsic aetiologies</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Aug 2025 07:12:20 +0000</pubDate>
        </item>
        <item>
            <title>carfentanil</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=carfentanil</link>
            <description>carfentanil

see also:

	* opiates and opioids

Introduction

	* extremely potent and very dangerous opiate used primarily to tranquilize elephants
	* adult human dose is 1mcg
		* lethal dose is 20mcg!</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 08 Sep 2020 10:01:00 +0000</pubDate>
        </item>
        <item>
            <title>carpal tunnel syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=carpal_tunnel</link>
            <description>carpal tunnel syndrome

see also:

	* paraesthesiae or numbness
	* Wesley Hand Centre's patient information sheet (pdf)
	* Victorian Better Health Channel - carpal tunnel syndrome
	* The Women's - Mx guidelines for pregnant women
	* WorkCover SA
	* NINDS Carpal Tunnel Syndrome Fact Sheet

introduction

	* this is a common problem mainly affecting adults, particularly line assembly workers, typists or those in 2nd or 3rd trimester pregnancy
	* it is due to compression of the median nerve within t…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 12 Jul 2013 07:47:38 +0000</pubDate>
        </item>
        <item>
            <title>CAR T cell therapy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cartcell</link>
            <description>CAR T cell therapy

see also:

	* chemotherapy for cancers
	* lymphoma
	* leukaemia
	* multiple myeloma

Introduction

	* CAR T cell therapy is a form of immunotherapy in which a patient’s own T lymphocytes are genetically engineered to better recognize and kill cancer cells (especially used in some types of non-Hodgkins lymphoma, relapsed or refractory B‑cell acute lymphoblastic leukemia and relapsed or refractory multiple myeloma )</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 08 Dec 2025 20:15:19 +0000</pubDate>
        </item>
        <item>
            <title>Carvedilol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=carvedilol</link>
            <description>Carvedilol

see also beta blockers

Summary:

	* long term Rx with carvedilol was shown to reduce mortality in systolic heart failure as well as reducing symptoms &amp; improving well-being. Carvedilol also has anti-oxidant, antiproliferative &amp; anti-endothelin properties.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 14 Sep 2008 13:04:31 +0000</pubDate>
        </item>
        <item>
            <title>cataracts</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cataracts</link>
            <description>cataracts

see also:

	* ophthalmology
	* Semin Cell Dev Biol. 2008 Apr; 19(2): 134–149.  a nice article summarising the pathophysiology and genetics of cataracts

introduction

	* cataracts occur when the proteins in the lens of the eye undergo changes resulting in opacification of the lens and are the leading cause of blindness in Western cultures
	* crystallins are the major soluble structural proteins in the lens and in humans comprise 3 major classes encoded by multiple genes: the α-, β-, a…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 02 Apr 2015 13:31:35 +0000</pubDate>
        </item>
        <item>
            <title>cathelicidins</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cathelicidins</link>
            <description>cathelicidins

see also:

	* innate immunity
	* lysozyme (LYZ)

Introduction

	* cathelicidins are a family of antimicrobial peptides characterized by a conserved cathelin domain and a variable antimicrobial peptide domain
	*  they disrupt bacterial cell membranes, leading to cell death.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 09 Jul 2025 05:30:17 +0000</pubDate>
        </item>
        <item>
            <title>cat scratch disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cat_scratch</link>
            <description>cat scratch disease

see also:

	* lymphadenopathy
	* &lt;https://www.cdc.gov/healthypets/diseases/cat-scratch.html&gt;

introduction

	* cat scratch fever or cat scratch disease is caused by a bacteria Bartonella henselae present in the saliva of some cats which enters the human via a scratch, or on the open eye - in which case a granulomatous conjunctivitis with preauricular LNs (</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 28 Jul 2022 01:19:35 +0000</pubDate>
        </item>
        <item>
            <title>congestive cardiac failure</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ccf</link>
            <description>congestive cardiac failure

see also:

	* cardiology
	* cor pulmonale
	* acute pulmonary oedema (APO)
	* Mx of the wheezy elderly patient - acute pulmonary oedema versus asthma
	* AFTB lectures - APO
	* heart failure with preserved EF (HFpEF)
	* heart failure with reduced ejection fraction (HFrEF)
	* NB. age &gt; 65 with primary Dx of CCF are admitted to cardio-geriatric unit at Western Hospital if present to Western Health
	* ScienceOpen Dec 2023: Heart Failure Guideline Directed Medical Therapy: …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 07 Dec 2023 02:41:39 +0000</pubDate>
        </item>
        <item>
            <title>cholecystokinin (CCK)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cck</link>
            <description>cholecystokinin (CCK)

see also:

	* insulin
	* glucagon
	* ghrelin

Introduction

	* Cholecystokinin regulates gastrointestinal functions, including inhibition of gastric emptying and food intake through activation of CCK-1 receptors on vagal afferent fibers innervating the gut.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 13 Feb 2022 07:20:08 +0000</pubDate>
        </item>
        <item>
            <title>CCL2/CCR chemokine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ccl2</link>
            <description>CCL2/CCR chemokine

see also:

	* chemokines
	* cytokines
	* interleukin-6 (IL-6)
	* cachexia

Introduction

	* CCL2 is the monocyte chemokine C-C motif ligand (CCL) 2
		*  also called small inducible cytokine A2

	*  CCL2 is a member of the CC chemokine superfamily, which binds to its receptor, C-C motif chemokine receptor-2 (CCR2), for the induction of chemotactic activity and an increase of calcium influx to induce monocyte infiltration and mediate inflammation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Aug 2025 04:46:19 +0000</pubDate>
        </item>
        <item>
            <title>ceftriaxone</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ceftriaxone</link>
            <description>ceftriaxone

see also:

	* cephalosporins

introduction

	* a 3rd generation broad spectrum parenteral cephalosporin
	* similar antibiotic coverage to cefotaxime but can be given in once daily or twice daily dosing.
	* im doses are usually given with local anaesthetic added
	* category B1 for pregnancy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 09 Jan 2012 02:56:59 +0000</pubDate>
        </item>
        <item>
            <title>cellular physiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cell</link>
            <description>cellular physiology

see also:

	* cellular physiology - endoplasmic reticulum

Introduction

Organelles and other cellular components

nucleus

	* contains the genetic material (DNA), RNA to create proteins, and proteins to maintain correct folding and functioning of the nucleus components as well as transport across the nucleus membrane</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Apr 2026 00:31:04 +0000</pubDate>
        </item>
        <item>
            <title>cellulitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cellulitis</link>
            <description>cellulitis

see also:

	* streptococcus / streptococcal infections
	* necrotizing fasciitis
	* cracked heels
	* venous leg ulcers
	* sepsis / septicaemia
	* Periorbital and orbital cellulitis
	* perichondritis / ear/auricle/pinna cellulitis 

introduction

	* cellulitis is a spreading, deep skin and subcutaneous fat infection characterized by poorly demarcated erythema, swelling, warmth, and tenderness
	* there is often a linear proximal erythema of lymphangitis +/- tender regional lymphadenopat…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 19 Feb 2024 02:36:11 +0000</pubDate>
        </item>
        <item>
            <title>cellular physiology - endoplasmic reticulum</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cell_er</link>
            <description>cellular physiology - endoplasmic reticulum

see also:

	* cellular physiology

Introduction

endoplasmic reticulum

	* the cells of all animals, plants and fungi contain specialised criss-crossing of tubes and membranes called endoplasmic reticulum (ER)
	* endoplasmic reticulum is essentially a factory in which proteins, lipids and hormones are manufactured, folded into their three-dimensional structure and modified</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 02 Jan 2024 23:43:31 +0000</pubDate>
        </item>
        <item>
            <title>centipede bites</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=centipedes</link>
            <description>centipede bites

see also:

	* insect bites and stings

Introduction

	* centipedes are widespread around the world and Australia is home to many species, some of which are native to Australia
	* centipedes are solitary, nocturnal fast moving predators, usually around 10cm in length but some Australian species such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 May 2020 13:18:47 +0000</pubDate>
        </item>
        <item>
            <title>cephalosporins</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cephalosporins</link>
            <description>cephalosporins

see also;

	* antibiotics
	* wikipedia

introduction

	* similar to penicillins, cephalosporins are beta lactam ring antibiotics which kill bacteria by compromising their cell wall
	* generally NOT active against LAME : Listeria, Atypicals (including Mycoplasma and Chlamydia), MRSA, enterococci</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 02 Apr 2017 23:06:06 +0000</pubDate>
        </item>
        <item>
            <title>Cerebral palsy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cerebral_palsy</link>
            <description>Cerebral palsy

	* RCH guideline - cerebral palsy
	* RCH guideline - cerebral palsy - chest infection
	* RCH guideline - cerebral palsy - increased seizures
	* RCH guideline - cerebral palsy - pain &amp; irritability</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 14:23:14 +0000</pubDate>
        </item>
        <item>
            <title>cervical disc prolapse</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cervical_disc_prolapse</link>
            <description>cervical disc prolapse

see also:

	* lumbar disc prolapse

Introduction

	* cervical disc prolapse occcurs in 0.5-2% of the population and is thus a relatively common cause of neck or radicular pain radiating to one or both arms
	* it is usually due to degeneration of the disc but may be caused by an acute traumatic injury such as direct impact</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 22 Jan 2021 23:03:46 +0000</pubDate>
        </item>
        <item>
            <title>cauda equina syndrome (CES)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ces</link>
            <description>cauda equina syndrome (CES)

see also:

	* back pain in the ED

introduction

	* an important complication of various conditions which cause low back pain (although it can occur without back pain), which requires urgent MRI to avoid delay in surgical Rx which increases risk of permanent urinary +/- faecal incontinence.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 31 Jan 2020 02:57:37 +0000</pubDate>
        </item>
        <item>
            <title>CHA2DS2-VASc score for determining stroke risk in patients with non-valvular AF</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cha2ds2-vasc</link>
            <description>CHA2DS2-VASc score for determining stroke risk in patients with non-valvular AF

see also:

	* atrial fibrillation
	* antithrombotic Rx for prevention of stroke
	* CHADS2 score for determining stroke risk in patients with non-valvular AF

scoring system

	* acronym stands for: 
		* Congestive heart failure/left ventricular dysfunction, Hypertension, Age ≥75 [doubled], Diabetes, Stroke [doubled] – Vascular disease, Age 65–74, and Sex category [female]).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 04 Apr 2014 05:20:24 +0000</pubDate>
        </item>
        <item>
            <title>CHADS2 score for determining stroke risk in patients with non-valvular AF</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chads2</link>
            <description>CHADS2 score for determining stroke risk in patients with non-valvular AF

see also:

	* atrial fibrillation
	* antithrombotic Rx for prevention of stroke

scoring system

	* score 1 point for each item present, but 2 points for PH stroke or TIA:
PH congestive cardiac failure PH hypertension  age &gt; 74 yrs diabetes mellitus  PH stroke (CVA) or transient ischaemic attack (TIA) 
risk of stroke in patients with AF</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 04 Apr 2014 05:02:00 +0000</pubDate>
        </item>
        <item>
            <title>Chagas disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chagas</link>
            <description>Chagas disease

see also:

	* parasites

Introduction

	* Chagas disease (aka American trypanosomiasis) is a chronic, indolent infection by the flagellate parasite Trypanosoma cruzi which may cause serious cardiac disease many years after it was acquired
	* 1st described in 1909 by the Brazilian physician and epidemiologist Carlos Chagas</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 23 Aug 2018 02:37:21 +0000</pubDate>
        </item>
        <item>
            <title>congenital heart disease (CHD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chd</link>
            <description>congenital heart disease (CHD)

see also:

	* cardiology
	* paediatric emergency medicine
	* Cyanotic spells in children

ECG changes in patients with CHD



CHD with normal ECG

	* PDA
	* mild-mod. valvular pulmonary stenosis
	* coarctation of aorta (20%)
	* d-Transposition of the great vessels
	* ASD
	* VSD

CHD with possible RVH</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 24 Apr 2013 07:40:32 +0000</pubDate>
        </item>
        <item>
            <title>angular cheilitis (cracked corners of the mouth)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cheilitis</link>
            <description>angular cheilitis (cracked corners of the mouth)

see also:

	* dermatology

aetiology

	* contact dermatitis from saliva +/- super-infection with bacteria or fungi such as Candida (20% as sole pathogen, present in &gt; 90% of all cases), Staph (20%), b-haem. Strept (8-15%)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Apr 2014 07:03:13 +0000</pubDate>
        </item>
        <item>
            <title>chemokines</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chemokines</link>
            <description>chemokines

see also:

	* cytokines
	* innate immunity

Introduction

	* chemokines are a chemotactic cytokines, that plays a crucial role in the immune system by directing the movement of immune cells, particularly leukocytes (white blood cells), to areas of inflammation or infection</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Aug 2025 05:25:05 +0000</pubDate>
        </item>
        <item>
            <title>chemotherapy for cancers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chemotherapy</link>
            <description>chemotherapy for cancers

see also:

	* cytotoxic agents
	* oncology
	* neoplasia / cancer / tumours
	* bone marrow transplant (BMT)
	* CAR T cell therapy

Introduction

	* chemotherapy is a general term used mainly for systemic use of cytotoxic anti-cancer drugs which kill rapidly dividing cells such as cancer cells
	* ~30% of individuals with cancer, and thus approximately 10% of the whole population in developed countries, are exposed to chemotherapy at some point in their lifetime</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 08 Dec 2025 19:57:58 +0000</pubDate>
        </item>
        <item>
            <title>the adult patient with chest pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chestpain</link>
            <description>the adult patient with chest pain in the ED

see also:

	* cardiology
	* template to assist in the discharge documentation of low risk chest pain
	* ACS rule out algorithm for the adult patient with chest pain in the ED
	* Western Health ED: pain medications instruction sheet (pdf)
	* Western Health ED: adult chest pain discharge instruction sheet (pdf)
	* Safer Care Vic patient information sheet on adult chest pain

	* strongly consider dissection and need for urgent CT angiogram in those aged …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 23 Jul 2024 13:40:38 +0000</pubDate>
        </item>
        <item>
            <title>template to assist in the discharge documentation of low risk chest pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chestpain_notation</link>
            <description>template to assist in the discharge documentation of low risk chest pain

see also:

	* the adult patient with chest pain in the ED
	* template to assist in the discharge documentation of suspected PE SSU admits
	* Western Health ED: pain medications instruction sheet (pdf)
	* Western Health ED: adult chest pain discharge instruction sheet (pdf)

example notations to copy and paste

general conclusive notation

initial statement

No definitive cause for this patient's chest pain was found at thi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Apr 2015 07:00:21 +0000</pubDate>
        </item>
        <item>
            <title>ACS rule out algorithm for the adult patient with chest pain in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chestpain_ruleout</link>
            <description>ACS rule out algorithm for the adult patient with chest pain in the ED

see also:

	* cardiology
	* template to assist in the discharge documentation of low risk chest pain
	* the adult patient with chest pain in the ED

Rapid ACS rule out algorithm 2024

	* consider other causes of chest pain in particular: PE, aortic dissection which need their own emergent work up, often including D-Dimer +/- emergent CTPA or CT aortogram</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 31 May 2025 03:13:17 +0000</pubDate>
        </item>
        <item>
            <title>chikungunya virus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chikungunya</link>
            <description>chikungunya virus

see also:

	* &lt;https://www.who.int/news-room/fact-sheets/detail/chikungunya&gt;

Introduction

	* arboviral infection spread by mosquitoes found mostly in West and East Africa, around the Indian Ocean, Asia, and South East Asis including the Pacific Islands
	* NOT acquired in Australia - no known cases as of 2025 although the mosquitoes which can transmit it (</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 03:59:58 +0000</pubDate>
        </item>
        <item>
            <title>Chilaiditi syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chilaiditi_syndrome</link>
            <description>Chilaiditi syndrome

see also:

	* the chest X-ray (CXR)

introduction

	* a generally benign CXR finding of bowel gas under right diaphragm between the diaphragm and the liver which occurs in some 1% of older adults
	* should not be confused with free gas which may be a surgical emergency</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 06 Nov 2013 04:22:06 +0000</pubDate>
        </item>
        <item>
            <title>chlorpromazine (Largactil)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chlorpromazine</link>
            <description>chlorpromazine (Largactil)

see also: anti-psychotic medications, migraine

introduction:

	* a phenothiazine medication used as a neuroleptic major tranquilliser in acute psychotic states as well as one of the most effective treatments of acute migraine headaches.
	* half life ~ 30hrs, eliminated by the liver.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 20 Apr 2009 06:07:21 +0000</pubDate>
        </item>
        <item>
            <title>ascending cholangitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cholangitis</link>
            <description>ascending cholangitis

see also:

	* jaundice (icterus)
	* cholelithiasis (gallstones)
	* the patient with acute RUQ pain in ED
	* see EMedicine.com for more details

introduction

	* ascending cholangitis is sepsis of the biliary tree other than just the gallbladder, resulting from obstruction of the CBD, usually by a gallstone in the CBD (choledocholithiasis), or from extension of sepsis from</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 23 Dec 2018 08:58:04 +0000</pubDate>
        </item>
        <item>
            <title>cholecystitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cholecystitis</link>
            <description>cholecystitis

see also:

	* the patient with acute RUQ pain in ED
	* biliary colic
	* ascending cholangitis
	* USC Essentials 2008 conference video - how not to miss the diagnosis of acute cholecystitis - subscription required
	* Western Health surgical pathway - cholecystitis

introduction

	* 90% are due to cholelithiasis (gallstones)
	* 10% are acalculous:
		* these patients are generally very unwell hospitalised patients such as post-op or ICU patients, but it may occur in outpatients
		* h…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 23 Apr 2024 07:03:28 +0000</pubDate>
        </item>
        <item>
            <title>cholelithiasis (gallstones)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cholelithiasis</link>
            <description>cholelithiasis (gallstones)

see also:

	* the patient with acute RUQ pain in ED
	* biliary colic
	* cholecystitis
	* ascending cholangitis
	* jaundice (icterus)
	* gallbladder and bile duct tumours

	* 10-20% of adults in Western cultures have gallstones, this may or may not be the cause of the clinical presentation!
	* cholesterol stones are not confined to patients who are Fat, Female, Fertile and Forty, but prevalence generally starts to rise after puberty and men also get these stones, albe…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 27 Mar 2026 22:15:36 +0000</pubDate>
        </item>
        <item>
            <title>cholera</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cholera</link>
            <description>cholera

see also:

	* travel medicine
	* gastroenteritis
	* clinically important bacteria
	* WHO fact sheet

introduction

	* an acute intestinal infection caused by ingestion of food or water contaminated with the bacterium Vibrio cholerae
	* 3–5 million cholera cases and 100 000–120 000 deaths worldwide due to cholera every year</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 31 Dec 2013 03:49:06 +0000</pubDate>
        </item>
        <item>
            <title>carbohydrates and sugars</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chos</link>
            <description>carbohydrates and sugars

see also:

	* lactose
	* fructose
	* irritable bowel syndrome (IBS)
	* obesity and weight management

Introduction

	* carbohydrates are biologic molecules consisting of carbon, hydrogen and oxygen, usually with the empirical formula of Cm(H2O)n (except for deoxyribose which is in DNA) and form a substantive part of animal diets and energy supply</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 20 Apr 2025 02:35:18 +0000</pubDate>
        </item>
        <item>
            <title>chronic pelvic pain in women</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chronicpelvicpain</link>
            <description>chronic pelvic pain in women

see also:

	* gynaecology
	* endometriosis
	* pelvic inflammatory disease (PID)
	* dysmenorrhoea
	* dyspareunia
	* &lt;https://www.racgp.org.au/afp/2015/july/management-of-persistent-pelvic-pain-in-girls-and-women/&gt;
	* RANZCOG patient information Chronic Pelvic Pain (pdf)
	* BMJ 2010: Chronic pelvic pain in women Clinical Review
	* RWH Melbourne The Women's Chronic Pelvic Pain clinic

introduction

	* a large proportion of women experience pelvic pain, often over years…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 02:14:16 +0000</pubDate>
        </item>
        <item>
            <title>chronic bronchitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chronic_bronchitis</link>
            <description>chronic bronchitis

see also:

	* chronic obstructive pulmonary disease (COPD)
	* the persistent cough
	* ACCP Evidence-Based Clinical Practice Guidelines publiched in Chest Journal (pdf) 

introduction

	* normally, about 500mL of sputum is produced each day, and it is usually not noticed. Smokers with chronic bronchitis produce larger amounts of sputum each day, as much as 100 mL/d more than normal.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 13 Apr 2012 06:34:00 +0000</pubDate>
        </item>
        <item>
            <title>Chronic fatigue syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=chronic_fatigue_syndrome</link>
            <description>Chronic fatigue syndrome

see DDx and Ix of persistent fatigue; psychiatry and mental health; rheumatology; sleep hygiene

Introduction:

	* prevalence of CFS in community is 0.2-0.7%
	* predominantly effects young adults
	* occurs in individuals from all socioeconomic groups
	* whilst most fatigue syndromes are of short duration &amp; resolve spontaneously, people with CFS for more than 5 yrs tend to remain symptomatic, although function may improve slowly over time. A US study estimated a cumulati…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 22 Jul 2011 15:13:04 +0000</pubDate>
        </item>
        <item>
            <title>chronic inflammatory demyelinating polyneuropathy (CIDP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cidp</link>
            <description>chronic inflammatory demyelinating polyneuropathy (CIDP)

see also:

	* neurology
	* Guillain-Barre syndrome (GBS)

Introduction

	* thought to be a an extremely rare chronic form of Guillain-Barre syndrome (GBS)
	* it has been associated with
		*  diabetes mellitus
		*  HIV / AIDS
		*  paraproteinaemias</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 19 Apr 2019 10:03:40 +0000</pubDate>
        </item>
        <item>
            <title>ciguatera toxin reef fish food poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ciguatera</link>
            <description>ciguatera toxin reef fish food poisoning

see also:

	* toxinology
	* illness after eating seafood
	* food poisoning
	* scombroid histamine food poisoning due to spoiled fish

introduction

	* ciguatera poisoning is the 2nd most common chemical agent food poisoning after scombroid histamine food poisoning due to spoiled fish
	* it is caused by consumption of reef fish contaminated with ciguatoxin, which originates with certain dinoflagellates (algae) associated with coral reef systems and accumu…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Aug 2024 06:34:15 +0000</pubDate>
        </item>
        <item>
            <title>ciliopathies</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ciliopathies</link>
            <description>ciliopathies

introduction

	* ciliopathies refers to a group of conditions characterised by impaired cilia function
	* normal ciliary beat frequency is 1000-1500 beats per minute. 
	* the frequency is slower in the peripheral airways (eg, bronchioles) compared to the larger airways (eg, trachea).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Apr 2014 04:25:58 +0000</pubDate>
        </item>
        <item>
            <title>ciprofloxacin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ciprofloxacin</link>
            <description>ciprofloxacin

see also:

	* flouroquinolone antibiotics

introduction

	* a member of the flouroquinolone antibiotics antibiotics
	* active against a variety of Gram -ves &amp; +ves by inhib. of DNA gyrase
	* activity includes Enterobacteriacaea, Pseudomonas, Neisseria, and at higher levels, Staph, Legionella, Chlamydia &amp; some mycobacteria with anaerobes being less susceptible.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 05:38:45 +0000</pubDate>
        </item>
        <item>
            <title>cirrhosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cirrhosis</link>
            <description>cirrhosis

see also:

	* ethanol (alcohol and alcohol withdrawal)
	* steatohepatitis (fatty liver)
	* gastroenterology
	* prescribing drugs in patients with liver impairment
	* hepatitis
	* assessment of hepatic function
	* hepatic encephalopathy
	* hepatocellular carcinoma

Pathology:

	* a generic term for an end stage of chronic liver disease characterised by destruction of hepatocytes &amp; loss of normal hepatic architecture, with replacement by fibrotic tissue &amp; regenerative nodules</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 Jan 2025 22:50:18 +0000</pubDate>
        </item>
        <item>
            <title>creatinine kinase (CK)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ck</link>
            <description>creatinine kinase (CK)

see also:

	* myopathy / myositis / muscle aches and pains
	* rhabdomyolysis

introduction

	* CK is a serum protein that is raised in any condition which causes damage to muscle cells, including the heart 
	* it's use as a cardiac marker for acute myocardial infarction (AMI/STEMI/NSTEMI) has now been largely replaced by troponin levels which are more specific for cardiac damage than even the CK-</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 21 Oct 2013 04:44:03 +0000</pubDate>
        </item>
        <item>
            <title>clinical image banks</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=clinical_images</link>
            <description>clinical image banks

see also:

	* online radiology image banks

Australian emergency medicine online clinical image banks

	* Life in the Fast Lane - clinical images and blogs</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 21 Dec 2011 13:24:31 +0000</pubDate>
        </item>
        <item>
            <title>clinical procedures in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=clinical_procedures</link>
            <description>clinical procedures in the ED

see also:

	* aseptic non-touch technique (ANTT)
	* minimum coagulation parameters for safe invasive procedures in the ED
	* procedural sedation

	* cardiopulmonary resuscitation:
		* cardiac arrest and asytole
		* neonatal resuscitation


	* emergency intubation
		* EMRAPTV Episode 31: Glidescope demo
		* EM-blog - tips on using the bougie for difficult airways
		* EmergentProcedures video via Austin EDteaching.com - gum elastic bougie mp4 video


	* surgical airw…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Mar 2026 04:55:33 +0000</pubDate>
        </item>
        <item>
            <title>clinical signs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=clinical_signs</link>
            <description>clinical signs

dermatologic signs

general

	* the petechial rash / purpura
	* Fever with petechial or purpuric rash
	* the linear skin lesion or rash
	* vesicular rashes
	* bullous / blistering rashes
	* skin necrosis
	* urticaria
	* extra-articular clinical features of rheumatologic conditions

orofacial

	* mouth ulcers

fingers and nails

	* koilonychia
	* clubbing
	* Raynaud's phenomenon

legs

	* erythema nodosum
	* leg_ulcers
	* peripheral vascular disease (PVD or PAD)

neurologic

	* se…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 02 Oct 2012 09:22:02 +0000</pubDate>
        </item>
        <item>
            <title>Clinical pathology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=clinpath</link>
            <description>Clinical pathology

	* C reactive protein (CRP)
	* Aust Presc 2007 - cell markers in clinical diagnosis
	* Aust Presc 2007 - Evaluation of adrenocortical function in adults</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Dec 2008 04:19:58 +0000</pubDate>
        </item>
        <item>
            <title>clonazepam</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=clonazepam</link>
            <description>clonazepam

see also benzodiazepines, anticonvulsants

Summary:

	* Rivotril
	* Unusually potent at antag. effects of pentylenetetrazol but almost without action in ECT-induced seizures thus has anticonvulsant activity in wide range of seizure type with notable exception of generalised tonic-clonic seizures &amp; thus useful in absences &amp; myoclonic seizures in children but tolerance to these actions often develop after 1-6mths when no dose of clonazepam will be of use!!;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Aug 2011 11:22:59 +0000</pubDate>
        </item>
        <item>
            <title>clonidine (Catapres)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=clonidine</link>
            <description>clonidine (Catapres)

see also:

	* antihypertensives

Introduction

	* Centrally acting alpha 2 adrenergic agonist
	* Appears to reduce neurally mediated plasma catecholamine levels
	* Primarily used as an antihypertensive but has also been used to Rx:
		* has been used to prevent</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Jan 2017 05:47:31 +0000</pubDate>
        </item>
        <item>
            <title>clopidogrel</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=clopidogrel</link>
            <description>clopidogrel

see also:

	* antiplatelet agents

introduction

	* platelet aggregation inhibitor used in prophylaxis of thromboembolic disorders and  with aspirin (acetylsalicylic acid) in acute coronary syndrome
	* marketed as Plavix and Iscover.
	* prodrug that requires hepatic metabolism (partly by CYP2C19) to become biologically active as a platelet inhibitor.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Dec 2014 05:22:28 +0000</pubDate>
        </item>
        <item>
            <title>Clostridium difficile</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=clostridium_difficile</link>
            <description>Clostridium difficile

see also:

	* clinically important bacteria
	* gastroenteritis
	* botulism
	* Australian Healthcare Special Interest Group
	* Clinical practice guidelines - USA

introduction

	* Clostridium difficile is a Gram positive, anaerobic, heat-resistant spore forming bacillus which is a common cause of antibiotic-related nosocomial colitis, and in its severe form,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Jun 2023 05:49:28 +0000</pubDate>
        </item>
        <item>
            <title>clozapine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=clozapine</link>
            <description>clozapine

see also:

	* anti-psychotic medications

introduction

	* a newer dibenzodiazepine antipsychotic agent which remains unique in its ability to alleviate the symptoms of patients with refractory illness (30%–40% of patients appear to be “resistant” to other anti-psychotic medications)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 Oct 2024 00:24:53 +0000</pubDate>
        </item>
        <item>
            <title>clubbing</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=clubbing</link>
            <description>clubbing

see also:

	* clinical signs

	* emedicine for more details

introduction

	* clubbing of the nails in association with lung infection was 1st described by Hippocrates
	* mechanism is unclear

4 phases of clubbing

	* nail bed fluctuation
	* loss of the normal nail-cuticle angle (Lovibond angle which is normally 15deg)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 02 Oct 2012 08:32:44 +0000</pubDate>
        </item>
        <item>
            <title>cmag</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cmag</link>
            <description>*  Notify senior ED doctor
	*  State indication for intubation 
	*  ROLES allocated;
	*  Airway nurse &amp; airway doctor
	*  Scribe nurse &amp; Team leader
	*  Drugs doctor &amp; Scout nurse
	*  Don PPE and buddy check
	*  PLAN discussed - including plan B, C and SURGICAL AIRWAY</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 08 Sep 2020 13:00:40 +0000</pubDate>
        </item>
        <item>
            <title>tryptophan C-mannosyltransferase (CMT enzyme protein)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cmtprotein</link>
            <description>tryptophan C-mannosyltransferase (CMT enzyme protein)

see also:

	* cytokines

Introduction

	* discovered in 2022, tryptophan C-mannosyltransferase (CMT) is a small enzyme protein which results in C-mannosylation of tryptophan side chains or some 20% of all secretory proteins and is important in cell-to-cell communications especially with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2023 21:46:32 +0000</pubDate>
        </item>
        <item>
            <title>cytomegalovirus (CMV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cmv</link>
            <description>cytomegalovirus (CMV)

see also:

	* viruses
	* EBV / glandular fever / infectious mononucleosis

Introduction

	* CMV is a member of the Herpesviridae family
	* ~60% of western populations have been infected with CMV, most are asymptomatic, but it may become reactivated if T-cell immunity falls
	* appears to be the cause of glioblastoma multiforme</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 08 Dec 2025 01:30:32 +0000</pubDate>
        </item>
        <item>
            <title>Co-Phenylcaine Forte Spray</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=co-phenylcaine</link>
            <description>Co-Phenylcaine Forte Spray

	* excessive topical use may cause hypertensive crisis which may be fatal, and attempts to treat such alpha agonist crises with beta adrenergic blockers or calcium channel blockers may cause acute pulmonary oedema (APO) and thus these agents are contra-indicated!! 

	* excessive topical use may cause</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Oct 2025 00:45:33 +0000</pubDate>
        </item>
        <item>
            <title>carbon monoxide poisoning (CO)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=co</link>
            <description>carbon monoxide poisoning (CO)

see also:

	* headache
	* hypoxia

introduction

	* carbon monoxide is an odourless gas which can cause insidious poisoning resulting in death
	* this is particularly likely in enclosed rooms or in cars (car exhaust fumes piped back into cars are a common mode of suicidality)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 May 2013 07:58:31 +0000</pubDate>
        </item>
        <item>
            <title>coagulation pathways</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=coagulation</link>
            <description>coagulation pathways

see also:

	* thrombosis
	* deep venous thrombosis (DVT)
	* DVT prophylaxis
	* DVT prophylaxis for the surgical patient
	* DVT prophylaxis, anticoagulation and spinal anaesthesia or spinal cord injured patients
	* Ix of suspected pulmonary embolism (PE)
	* Mx of suspected DVT
	* Mx of lower limb DVT
	* Rx of venous thrombosis (DVT/PE) and superficial thrombophlebitis - American College of Chest Physicians guidelines 2012
	* DVT and post-thrombotic syndrome (PTS)
	* upper li…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Aug 2023 07:12:22 +0000</pubDate>
        </item>
        <item>
            <title>cocaine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cocaine</link>
            <description>cocaine

see also:

	* local anaesthetic agents
	* drug dependency
	* Mx of psychostimulant toxicity from amphetamines and related substances
	* intravenous drug users (IVDU) or injection drug use (IDU)

history

	* the 1st LA discovered, pure alkaloid isolated 1860 from leaves of Erythroxylon coca a bush in Andes growing @ 1000-3000m altitude;
	* studied as LA, Mx of morphine withdrawal, spinal anaesthetic from 1884;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 May 2011 05:38:20 +0000</pubDate>
        </item>
        <item>
            <title>codeine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=codeine</link>
            <description>codeine

see also:

	* opiates and opioids
oxycodonenon-steroidal anti-inflammatory drugs (NSAIDs)

introduction

	* codeine phosphate is an opioid analgesic which is also sometimes used as an antitussive agent.
	* its analgesic effect is thought to be due to its partial metabolic conversion to morphine
	* structurally similar to morphine and oxycodone so should be avoided in patients with hypersensitivities to these</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Apr 2012 07:22:27 +0000</pubDate>
        </item>
        <item>
            <title>coeliac disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=coeliac</link>
            <description>coeliac disease

see also: gastroenterology
here
Introduction

	* now known as gluten enteropathy
	* results from an abnormal immune response to gliadin, a component of dietary gluten, found in wheat, barley, rye and possibly oats. 
	* this causes villous atrophy of the small bowel mucosa, which in turn leads to</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Nov 2025 22:31:27 +0000</pubDate>
        </item>
        <item>
            <title>colchicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=colchicine</link>
            <description>colchicine

see also:

	*  pharmacology main index
	*  gout
	*  colchicine overdose

Historical:

 *used by ancient Greeks, so along with the opiates, is probably the earliest recorded medication still in current use

	* 6th C AD, Alexander of Tralles proposed use of colchicine for joint pain
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 03 Jan 2026 04:00:29 +0000</pubDate>
        </item>
        <item>
            <title>colitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=colitis</link>
            <description>colitis

see also:

	* central / periumbilical abdominal pain in the ED
	* diarrhoea

Introduction

	* colitis is inflammation of the large bowel
	* on a CT scan one of the main features is thickening of the large bowel wall and one should ascertain the distribution of the colitis as this has important ramifications for likely differentials</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Jun 2019 05:18:39 +0000</pubDate>
        </item>
        <item>
            <title>ischaemic colitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=colitis_ischaemic</link>
            <description>ischaemic colitis

see also:

	* the patient with acute abdominal pain in the ED
	* colitis

introduction

	* beware the patient with acute abdominal pain in the ED who also has atrial fibrillation - check their serum lactate level!

epidemiology

	* 90% occur in &gt;60 yr olds
	* younger pts tend to have either:
		* vascular disease
		* arteriosclerotic heart disease
		* diabetes
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 10 Aug 2018 15:29:28 +0000</pubDate>
        </item>
        <item>
            <title>collagen disorders</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=collagen</link>
            <description>collagen disorders

see also:

	* elastin disorders
	* connective tissue (CT) disorders
	* Marfan's syndrome
	* joint hypermobility disorders and syndromes

collagen

	* collagen refers to a group of proteins which are the main component of connective tissue and the most abundant protein in mammals making up 25-35% of total body protein.
	* 90% of total body collagen is of type I but there are at least 28 types of collagen, the most common are:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Mar 2023 20:23:58 +0000</pubDate>
        </item>
        <item>
            <title>color blindness / color vision deficiency</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=color_blindness</link>
            <description>color blindness / color vision deficiency

see also:

	* ophthalmology
	* eye color phenotypes and disease associations
	* &lt;https://enchroma.com/blogs/beyond-color/how-color-blind-see&gt;
	* &lt;https://enchroma.com/pages/types-of-color-blindness&gt;
	* Enchroma online color blindness test and link to corrective glasses - make sure you do this without any color correction settings applied to your computer display (check color filter in your settings!
	* there is also considerable variation amongst people…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 14 Oct 2024 10:15:38 +0000</pubDate>
        </item>
        <item>
            <title>the comatose patient</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=coma</link>
            <description>the comatose patient

	* RCH guideline - coma
	* Wikipedia - Glasgow coma score (GCS)
	* the acutely confused patient
	* delirium

introduction

	* coma or decreased conscious state is a common presentation or occurrence within the ED, and most are transient due to syncope / near syncope or post-ictal states.
	* decreased conscious state will reliably occur when cerebral perfusion falls to low (eg. hypotension or</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 20 Jan 2019 10:22:08 +0000</pubDate>
        </item>
        <item>
            <title>post-coma unresponsiveness (persistent vegetative state)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=coma_persistent</link>
            <description>post-coma unresponsiveness (persistent vegetative state)

see also:

	* the comatose patient
	* verification of brain death in the ventilated patient

post-coma unresponsiveness

	* the diagnosis of persistent vegetative state is difficult and usually protracted, often taking months to confirm.
	* in 2004, the National Health and Medical Research Council has released advice on this matter titled</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 05 Jan 2019 06:43:15 +0000</pubDate>
        </item>
        <item>
            <title>compartment syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=compartment_syndrome</link>
            <description>compartment syndrome

see also:

	* acute foot drop

Introduction

	* compartment syndrome is a surgical emergency as the increased pressures within a fascial compartment such as the lower leg compartments results in markedly reduced blood supply and progressive ischaemia and muscle and nerve infarction - muscle necrosis can occur quickly, within 3-4 hours of original injury and becomes irreversible within 4-8hrs</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Jan 2020 13:06:00 +0000</pubDate>
        </item>
        <item>
            <title>when are doctors required to compulsorily report patients in Australia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=compulsory_reporting</link>
            <description>when are doctors required to compulsorily report patients in Australia

see also:

	* Victorian govt - police and mental health patients
	* police and the ED

reportable deaths

	* see reportable and reviewable deaths - deaths which MUST be reported to the Coroner

notifiable diseases

	* Vic. DHS notification of notifiable infectious diseases

patients in residential aged care

	* &lt;http://www.health.gov.au/internet/main/publishing.nsf/Content/ageing-quality-guidelines-cr-ap.htm&gt;
	* compulsory r…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 08 Dec 2020 01:57:16 +0000</pubDate>
        </item>
        <item>
            <title>concussion</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=concussion</link>
            <description>concussion

see also:

	* head injury in the adult patient
	* paediatric head injury
	* &lt;https://www.concussioninsport.gov.au/medical_practitioners&gt;

Abbreviated Westmead PTA Scale (A-WPTAS)

	* see &lt;http://www.psy.mq.edu.au/pta/index.html&gt;
	* Motor Accident Authority of NSW - Traumatic Brain Injury
	* can be combined with GCS as an objective measure of post traumatic amnesia (PTA)
	* a patient is considered to be out of PTA when they score 18/18
	* should be used in conjuction with clinical jud…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 01 May 2021 23:28:50 +0000</pubDate>
        </item>
        <item>
            <title>cardiac conduction blocks</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cond_blocks</link>
            <description>cardiac conduction blocks

see also:

	* cardiology
	* The basics of reading an ECG
	* Fascicular heart blocks
	* Left Bundle Branch Block (LBBB)
	* Right Bundle Branch Block (RBBB)
	* sick sinus syndrome (SSS) / tachycardia-bradycardia syndrome

Introduction

	* cardiac conduction blocks are common and often found co-incidentally on ECGs taken for other reasons
	* most have a low probability of serious adverse events although some will result in syncopal episodes and warrant investigation and p…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 02 Aug 2025 11:51:24 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2008</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2008</link>
            <description>Event Calendar for 2008

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2009
	* Victorian school term dates
	* Gary's Melbourne event calendar
	* online conference directories:
		* ACEM calendar of events and conferences
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com
		* Yahoo conferences directory
		* Google conferences directory


January:

	* 1st: New Year's Day
	* 26-29t…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 07 Oct 2008 12:59:22 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2009</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2009</link>
            <description>Event Calendar for 2009

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2008
	* Conferences and event calendar for 2010
	* Victorian school term dates
	* Gary's Melbourne event calendar
	* online conference directories:
		* ACEM calendar of events and conferences
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com
		* Yahoo conferences directory
		* Google conferences directory

…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Sep 2009 00:35:07 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2010</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2010</link>
            <description>Event Calendar for 2010

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2011
	* Victorian school term dates
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com
		* Medical Events
		* DocGuide
		* MediCruises - 7 day conference cruises
		* Yahoo conferences directory
		* Google conferences directory

	* Ultrasoun…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 26 Jul 2010 01:39:26 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2011</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2011</link>
            <description>Event Calendar for 2011

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2012
	* ACEM calendars
	* Victorian school term dates
	* Gary's Melbourne event calendar
	* online conference directories:
		* Doctor's Review.com - one of the better conference search engines
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com
		* Yahoo conferences directory - very few medical conferences li…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Aug 2011 23:59:21 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2012</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2012</link>
            <description>Event Calendar for 2012

	* events and conferences relevant to ED professionals
	* ACEM calendar 2012 (pdf)
	* Austin ED teaching website calendar of conferences 2012
	* Conferences and event calendar for 2013
	* Victorian school term dates
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com
		* Yahoo conferences directory
		* Google conferences directory

…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 06 Sep 2012 13:37:59 +0000</pubDate>
        </item>
        <item>
            <title>event calendar for 2013 including conferences and main ACEM events</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2013</link>
            <description>event calendar for 2013 including conferences and main ACEM events

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2014
	* Victorian school term dates
	* Gary's Australian cultural event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com
		* IFEM calendar of ICEM conferences
		* &lt;http://www.wilderness-medicine.com/Wilderness Medicine co…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Jul 2013 06:24:35 +0000</pubDate>
        </item>
        <item>
            <title>conferences and event calendar for 2014</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2014</link>
            <description>conferences and event calendar for 2014

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2013
	* Conferences and event calendar for 2015
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	* TBA: Europe Pacific Medical &amp; Le…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Jun 2014 01:08:48 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2015</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2015</link>
            <description>Event Calendar for 2015

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2014
	* Conferences and event calendar for 2016
	* Victorian school term dates
	* Vic. public holidays
	* McMaster Uni BEEM courses
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	* 11-16th: 5th Annual…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Sep 2015 03:20:55 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2016</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2016</link>
            <description>Event Calendar for 2016

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2015
	* Conferences and event calendar for 2017
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	*  Australia Day

February:

	* new HMO, registrar…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Sep 2016 03:10:16 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2017</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2017</link>
            <description>Event Calendar for 2017

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2016
	* Conferences and event calendar for 2018
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


	* avoid WASET conferences as these are extremely low quality “conferences”

January…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Aug 2017 05:36:24 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2018</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2018</link>
            <description>Event Calendar for 2018

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2017
	* Conferences and event calendar for 2019
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com
		* &lt;https://www.medical.theconferencewebsite.com/conferences/emergency-medicine&gt;


Ja…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 10 Oct 2018 01:11:56 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2019</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2019</link>
            <description>Event Calendar for 2019

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2018
	* Conferences and event calendar for 2020
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	* 26th and 28th: Australia Day

February:

	* new …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 May 2019 13:24:45 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2020</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2020</link>
            <description>Event Calendar for 2020

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2019
	* Conferences and event calendar for 2021
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* NorthWest Seminars in Emergency Medicine USA
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	*…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Nov 2019 22:19:54 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2021</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2021</link>
            <description>Event Calendar for 2021

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2020
	* Conferences and event calendar for 2022
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	*  Australia Day

February:

	* new HMO, registrar…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Dec 2021 23:30:38 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2022</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2022</link>
            <description>Event Calendar for 2022

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2021
	* Conferences and event calendar for 2023
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* travelling to conferences in Malta
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	*  Australia…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Sep 2022 03:44:19 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2023</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2023</link>
            <description>Event Calendar for 2023

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2022
	* Conferences and event calendar for 2024
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	*  Australia Day
	*  18-20th: EMCORE Gold Coast Ql…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 11 Aug 2023 02:15:13 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2024</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2024</link>
            <description>Event Calendar for 2024

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2023
	* Conferences and event calendar for 2025
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	* 14-19th: RMH International Hokkaido Trauma Confe…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 16 Feb 2024 00:57:29 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2025</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2025</link>
            <description>Event Calendar for 2025

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2024
	* Conferences and event calendar for 2026
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* WH: Megan's list of conferences (intranet)
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	*  A…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 21 Jun 2025 05:01:11 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2026</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2026</link>
            <description>Event Calendar for 2026

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2025
	* Conferences and event calendar for 2027
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	*  Australia Day

February:

	* new HMO, registrar…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 19 Jan 2026 15:12:22 +0000</pubDate>
        </item>
        <item>
            <title>Event Calendar for 2027</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conf2027</link>
            <description>Event Calendar for 2027

	* events and conferences relevant to ED professionals
	* Conferences and event calendar for 2026
	* Conferences and event calendar for 2028
	* Victorian school term dates
	* Vic. public holidays
	* Gary's Melbourne event calendar
	* online conference directories:
		* American Centre for Medical Education (CCME) Emergency Medicine &amp; Acute Care Series courses
		* Medical Conferences.com


January:

	* 1st: New Year's Day
	*  Australia Day

February:

	* new HMO, registrar…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 04 Feb 2025 05:36:06 +0000</pubDate>
        </item>
        <item>
            <title>events and conferences relevant to ED professionals</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences</link>
            <description>events and conferences relevant to ED professionals

	* Victorian school term dates
	* Victorian public holidays
	* travel for international conferences - visas and travel authorisations
	* ATO travel allowances  per diem expenses, accommodation allowances
	* online conference directories:
		* ACEM calendar of events and conferences
		* Doctor's Review.com - one of the better conference search engines
		* Australian toxinology courses
		* Medicon - Medical Conferences
		* American Centre for Med…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 14 Jan 2019 08:14:08 +0000</pubDate>
        </item>
        <item>
            <title>travel to conferences in Argentina - ICEM 2020</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_argentina</link>
            <description>travel to conferences in Argentina - ICEM 2020

see also:

	* events and conferences relevant to ED professionals
	* travelling to New York for conferences
	* travelling to Hawaii for conferences
	* travelling to conferences in Malta
	* smartraveller.gov.au: travel safety in Argentina

Introduction

	* ICEM 2020 will be held in Buenos Aires 15-18th June 2020
	* Tourists can stay for up to 90 days without a visa.
	* Buenos Aires has high levels of air pollution
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 May 2022 03:52:46 +0000</pubDate>
        </item>
        <item>
            <title>travelling to conferences in Barcelona, Spain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_barcelona</link>
            <description>travelling to conferences in Barcelona, Spain

see also:

	* travelling to conferences in Rhodes, Greece
	* conferences_Madrid
	* travelling to conferences in Lisbon, Portugal

Introduction

	* Barcelona is host for Sept 2023 EusEM conference - 16-20th Sept 2023
	*  climate September:
		*  avg temperatures 15 - 30degC with 73% humidity
		*  sea temp 23degC
		*  avg rain 82mm raining on 6-8days (the 2nd wettest month of the year)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 24 Apr 2023 02:56:21 +0000</pubDate>
        </item>
        <item>
            <title>travelling to Canada for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_canada</link>
            <description>travelling to Canada for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* events and conferences relevant to ED professionals
	* travel insurance

Introduction

	* Air Canada partners with:
		*   Star Alliance, including Air New Zealand


	* if passing through USA, even though your online ESTA travel visa may be approved, you may not get past border security in the US if you have travelled to</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 18 Aug 2025 00:25:28 +0000</pubDate>
        </item>
        <item>
            <title>traveling to Croatia for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_croatia</link>
            <description>traveling to Croatia for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* traveling to Prague and Czech Republic for conferences
	* traveling to conferences in Italy

Introduction

	* main airport and capital is Zagreb which is inland and north-east, near the Slovenia border
	* Dalmatian coastal towns include:
		*  Pula
		*  Opatija
			*  cool-mild in early May with max temperatures ~18degC</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Apr 2026 08:55:27 +0000</pubDate>
        </item>
        <item>
            <title>traveling to conferences in Germany</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_germany</link>
            <description>traveling to conferences in Germany

see also:

	* travel for international conferences - visas and travel authorisations

Berlin

	* SMACC 2017 Currinda user account log in
	* SMACC 2017
		* pre-conference workshops: Monday June 26th 2017
		* conference at Tempodrom, Berlin Tues 27th-29th June 2017 
			* 40min, 3.3km walk to Museum district via Checkpoint Charlie and Gendarmemarkt</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Jun 2017 00:58:20 +0000</pubDate>
        </item>
        <item>
            <title>traveling to Greece for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_greece</link>
            <description>traveling to Greece for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* travelling to Iceland for conferences
	* travelling to conferences in Malta
	* traveling to conferences in Italy
	* traveling to Croatia for conferences
	* daylight savings ends Oct 27th 2018, sunset Oct 28th then 1hr earlier at 5.30pm
	* Ferries from island to island
	* wikipedia - list of Greek islands
		*  Ionian Islands are to the west of Greece (eg. Corfu, Kythira, Ce…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 May 2022 04:58:55 +0000</pubDate>
        </item>
        <item>
            <title>travelling to Hong Kong for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_hk</link>
            <description>travelling to Hong Kong for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* events and conferences relevant to ED professionals
	* traveling to Republic of Korea (South Korea) for conferences
	* travelling to Taiwan for conferences

introduction

	* unlike mainland China, most visitors do not need to obtain visas in advance
		* Australian tourists do not require visas for visits of less than 90 days

	*  if you fail to declare any banned or du…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 26 Feb 2024 04:11:04 +0000</pubDate>
        </item>
        <item>
            <title>travelling to Iceland for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_iceland</link>
            <description>travelling to Iceland for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* traveling to Greece for conferences

flights from Australia

IcelandAir connections

	* Iceland Air is the national carrier for Iceland and has flights to many European and north American cities
	* those coming from Australia will be most interested in getting a Iceland Air flight from either:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 26 Jun 2018 11:28:45 +0000</pubDate>
        </item>
        <item>
            <title>travelling to Ireland for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_ireland</link>
            <description>travelling to Ireland for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* events and conferences relevant to ED professionals
	* travel insurance

ICEM 2012 Dublin from Australia

	* June 27-30th 2012: ICEM 2012 website
		* preliminary programme (pdf)

	* June 25th-8th July: Wimbledon tennis - London
	* July 27th-12th Aug: Summer Olympic Games - London

flights

	* please check airlines for up to date details, the following is a guide only!</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 18 Dec 2015 07:27:15 +0000</pubDate>
        </item>
        <item>
            <title>traveling to conferences in Italy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_italy</link>
            <description>traveling to conferences in Italy

see also:

	* travel for international conferences - visas and travel authorisations
	* traveling to Prague and Czech Republic for conferences
	* traveling to Croatia for conferences
	* travelling to conferences in Malta
	* traveling to Greece for conferences

Venice

	* Venice Marco Polo Airport is 8km from Venice itself
		*  water bus transport
			*  airport to St Mark's Square Linea Arancio  (Line A) every 30min and takes 1hr to get to S'Angelo and costs aro…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 May 2022 03:54:15 +0000</pubDate>
        </item>
        <item>
            <title>travelling to Tokyo, Japan for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_japan</link>
            <description>travelling to Tokyo, Japan for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* events and conferences relevant to ED professionals
	* traveling to Republic of Korea (South Korea) for conferences
	* https://www.vjw.digital.go.jp/main/#/vjwplo001 Japan immigration website to enter your details prior to travel

Introduction

	* population of over 14 million residents as of 2023 (41m in Greater Tokyo) and the second-most-populated capital in the w…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 17 May 2025 11:43:34 +0000</pubDate>
        </item>
        <item>
            <title>traveling to Republic of Korea (South Korea) for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_koreasth</link>
            <description>traveling to Republic of Korea (South Korea) for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* events and conferences relevant to ED professionals
	* travelling to Tokyo, Japan for conferences
	* EM Asia 2016 conference - The K-Hotel, Seoul 24-26th Aug 2016
	* &lt;http://www.independent.co.uk/travel/asia/south-korea-from-busy-seoul-to-the-popular-island-of-jeju-busy-beaches-to-villages-steeped-in-folk-a6911506.html&gt;
	* Casa Seorak Sokcho
	* Sma…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 16 Oct 2024 09:31:15 +0000</pubDate>
        </item>
        <item>
            <title>travelling to conferences in Lisbon, Portugal</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_lisbon</link>
            <description>travelling to conferences in Lisbon, Portugal

see also:

	* travelling to conferences in Rhodes, Greece
	* conferences_Madrid
	* travelling to conferences in Barcelona, Spain

Introduction

	* a coastal city famed for its historic, rattling tram lines especially tram 28 into old Alfama town

Climate

	* mild Mediterranean climate 
	* short, mild and rainy winters and warm to hot, dry summers</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Feb 2023 05:55:19 +0000</pubDate>
        </item>
        <item>
            <title>travelling to conferences in Majorca, Spain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_majorca</link>
            <description>travelling to conferences in Majorca, Spain

see also:

	* traveling to conferences in Italy
	* travelling to conferences in Malta
	* travelling to conferences in Barcelona, Spain

Introduction

	* a 100km diameter, 3,640 km2, tourist island (aka Mallorca) near Barcelona, Valencia and Ibiza with a coastline of 623km
	* highest peak is Puig Major, at 1445 m but this is in a military zone so the highest accessible peak is Puig de Massanella at 1364m</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 19 Jan 2023 10:18:25 +0000</pubDate>
        </item>
        <item>
            <title>travelling to conferences in Malta</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_malta</link>
            <description>travelling to conferences in Malta

see also:

	* traveling to conferences in Italy
	* travelling to conferences in Majorca, Spain

Flights from Australia to Malta 2022

direct

	* Qantas/Emirates:
		*  Melb - Dubai = 14hrs
		*  Dubai - Malta via 1hr stopover in Larnarca, Cyprus = 8hrs
		*  eg. dep Melb Sat Sept 10th 2022 2115hrs EK407, arr. Malta 1405hrs Sun 11th Sept</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 02 Oct 2022 10:23:43 +0000</pubDate>
        </item>
        <item>
            <title>traveling to Oslo, Norway for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_oslo</link>
            <description>traveling to Oslo, Norway for conferences

see also:

	* travelling to conferences in Rhodes, Greece

Introduction

	* Aug 30th-2nd Sept 2023: 2023 European Association for the History of Medicine and Health: &quot;Crisis in Health and Medicine&quot; Oslo
	* Oslo (with neighbouring Sandvika-Asker) is built in a horseshoe shape on the northernmost shores of the Oslofjord and limited in most directions by hills and forests</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 09 Feb 2023 23:20:03 +0000</pubDate>
        </item>
        <item>
            <title>traveling to Prague and Czech Republic for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_prague</link>
            <description>traveling to Prague and Czech Republic for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* traveling to Croatia for conferences
	* wikipedia

Introduction

	* population of Prague is only 1.3 million but Prague is the fifth most visited European city after London, Paris, Istanbul and Rome with over 8 million tourists each year.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Apr 2019 10:28:55 +0000</pubDate>
        </item>
        <item>
            <title>travelling to conferences in Rhodes, Greece</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_rhodes</link>
            <description>travelling to conferences in Rhodes, Greece

see also:

	* travelling to conferences in Barcelona, Spain
	* traveling to Oslo, Norway for conferences
	* sandflies in the Greek islands:
		* &lt;https://www.researchgate.net/publication/6433342_Faunistic_study_of_sandflies_in_Greece&gt;
		* &lt;https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819154/&gt;


Introduction

	* Rhodes (Rodos) is one of the far eastern Greek islands lying just off the coast of Turkey which can be accessed via a ferry</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 20 Apr 2023 13:21:30 +0000</pubDate>
        </item>
        <item>
            <title>travelling to Taiwan for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_taiwan</link>
            <description>travelling to Taiwan for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* events and conferences relevant to ED professionals
	* traveling to Republic of Korea (South Korea) for conferences
	* travelling to Hong Kong for conferences
	* Taiwan customs requirements
		*  Some prescription medications are illegal in Taiwan
		*  Taiwan has a visa-exempt entry scheme for nationals of designated countries, including Australia. Australians can use Taiw…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Jun 2025 01:36:54 +0000</pubDate>
        </item>
        <item>
            <title>travelling to Hawaii for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_usa_hawaii</link>
            <description>travelling to Hawaii for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* events and conferences relevant to ED professionals
	* travelling to Canada for conferences
	* travel insurance

introduction

	* as for all travel to USA, you will need a travel visa - see travel for international conferences - visas and travel authorisations

	* even though your online ESTA travel visa may be approved, you may not get past border security in the US if y…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 18 Aug 2025 00:25:11 +0000</pubDate>
        </item>
        <item>
            <title>travelling to New York for conferences</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conferences_usa_ny</link>
            <description>travelling to New York for conferences

see also:

	* travel for international conferences - visas and travel authorisations
	* events and conferences relevant to ED professionals
	* travelling to Canada for conferences
	* travel insurance

introduction

	* as for all travel to USA, you will need a travel visa - see travel for international conferences - visas and travel authorisations

	* even though your online ESTA travel visa may be approved, you may not get past border security in the US if…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 18 Aug 2025 00:24:54 +0000</pubDate>
        </item>
        <item>
            <title>travel for international conferences - visas and travel authorisations</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conference_travel</link>
            <description>travel for international conferences - visas and travel authorisations

see also:

	* events and conferences relevant to ED professionals
	* travelling to New York for conferences
	* travelling to Hawaii for conferences
	* conferences_Europe
	* travelling to Ireland for conferences
	* travelling to Iceland for conferences
	* traveling to conferences in Germany
	* traveling to conferences in Italy
	* travelling to conferences in Malta
	* traveling to Greece for conferences
	* traveling to Croatia…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 16 Oct 2024 10:15:13 +0000</pubDate>
        </item>
        <item>
            <title>conflict of interest for employees of hospitals and members of committees and boards of management</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conflict_of_interest</link>
            <description>conflict of interest for employees of hospitals and members of committees and boards of management

see also:

	* medical professionalism
	* Vic government Conflict of Interest Policy

introduction

	* conflict of interest is a conflict between a person’s public duty to act in the best interests of the entity and his or her private interests and/or duty to another organisation.  A conflict of interest can arise from attempting to avoid personal losses, or gain personal advantage – whether financ…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Nov 2013 01:14:30 +0000</pubDate>
        </item>
        <item>
            <title>the acutely confused patient</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=confusion</link>
            <description>the acutely confused patient

see also:

	* the comatose patient
	* delirium

aetiology

hypoxia

	* see hypoxia
	* pneumonia, pulmonary embolism (PE), acute pulmonary oedema (APO)
	* pneumothorax
	* chest injury
	* respiratory depression
		* toxicology
		* myasthenia gravis
		* muscular dystrophy
		* painful chest wall trauma
		* head injury


drugs

	* intoxication or withdrawal</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 May 2013 08:09:51 +0000</pubDate>
        </item>
        <item>
            <title>conjunctivitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=conjunctivitis</link>
            <description>conjunctivitis

see also:

	* ophthalmology
	* acute atraumatic painful red eye(s)

Introduction

	* bilateral red eyes tend to be more likely due to either conjunctivitis, welder flash burns - UV keratopathy (photo keratitis), or chemical burns, the latter two generally also cause keratitis

	* if only one eye is red, take special care to exclude other important pathologies - see</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 Jan 2026 10:40:05 +0000</pubDate>
        </item>
        <item>
            <title>consciousness</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=consciousness</link>
            <description>consciousness

see also:

	* brain evolution and development
	* cerebrospinal fluid (CSF)
	* stroke (CVA)
	* neurology
	* the comatose patient
	* Youtube: an excellent talk on consciousness and also why AI is unlikely to gain true consciousness by Anil Seth March 2024

Introduction

	* clinicians take a rather simplistic approach to the concept of consciousness and conscious states without really defining consciousness but instead relying upon other measures such as state of alertness and state …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 01 Apr 2024 13:33:04 +0000</pubDate>
        </item>
        <item>
            <title>constipation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=constipation</link>
            <description>constipation

see also:

	* laxatives
	* RCH guideline - constipation

prevention of constipation

	* encourage good fluid intake with adequate dietary fibre
	* avoid repression of desire to use bowels
	* encourage regular bowel habits
	* increasing dietary fibre to the recommended daily intake of approximately 30 g or the use of fibre supplements such as psyllium should help in those patients with fibre deficiency.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 21 Jan 2026 00:29:45 +0000</pubDate>
        </item>
        <item>
            <title>contraception</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=contraception</link>
            <description>contraception

see:

	* gynaecology
	* post-coital emergency contraception
	* combined OCP
	* progestogens and progesterone-only contraceptives and hormonal Rx
	* Sexual Health &amp; Family Planning Australia - handbook on contraception

introduction

	* unintended pregnancies have a high psychosocial and often financial cost
	* most women and their partners, do not consider termination of these pregnancies without enormous psychologic stress at the time or the pregnancy, and later in life in often …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Sep 2013 02:30:19 +0000</pubDate>
        </item>
        <item>
            <title>radiologic contrast media precautions and adverse reactions</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=contrast_reactions</link>
            <description>radiologic contrast media precautions and adverse reactions

see also:

	* allergy and hypersensitivity reactions
	* anaphylaxis
	* radiology
	* Western Health policies (intranet only):
		* Contrast media administration guidelines
		* Interaction of Metformin with Intravascular Iodinated Contrast (docx)


introduction

	* iodinated radiocontrast materials are tri-iodinated benzoic acid derivatives that in solution contain a small amount of free iodide and are classified into:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Oct 2025 00:45:10 +0000</pubDate>
        </item>
        <item>
            <title>chronic obstructive pulmonary disease (COPD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=copd</link>
            <description>chronic obstructive pulmonary disease (COPD)

see also:

	* respiratory medicine
	* asthma
	* chronic bronchitis
	* home oxygen

introduction

	* COPD is the third leading cause of disease burden in Australia
	* it is often under-diagnosed and many do not receive optimal medical care
	* exacerbations can be caused by:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 11 Sep 2017 07:53:44 +0000</pubDate>
        </item>
        <item>
            <title>copper</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=copper</link>
            <description>copper

see also:

	* caeruloplasmin
	* Wilson's disease

Introduction

	* copper is an essential factor in all organisms, and once copper concentrations exceed the threshold maintained by homeostatic mechanisms, then copper in the body becomes toxic
	* the balance of copper as an important cofactor is crucial, as dysregulation of intracellular copper bioavailability will induce cytotoxicity and oxidative stress</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 Mar 2023 11:13:29 +0000</pubDate>
        </item>
        <item>
            <title>Mx of cord prolapse</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cord_prolapse</link>
            <description>Mx of cord prolapse

see labour

introduction

	* cord prolapse is the presentation of the cord first through the cervix once membranes rupture
	* this is an obstetric emergency as fetal circulation can be rapidly compromised
	* ALL staff caring for women in labour MUST know how to recognise and manage cord prolapse</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Apr 2013 06:18:20 +0000</pubDate>
        </item>
        <item>
            <title>corneal abrasions</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=corneal_abrasion</link>
            <description>corneal abrasions

see also:

	*  ophthalmology
	*  chemical injuries and burns to the eyes
	*  welder flash burns - UV keratopathy (photo keratitis)
	*  Eye injuries
	* RCH guideline - acute eye injuries in children
	* RCH guideline - penetrating eye injury
	* RCH guideline - the acute red eye

patient information sheets

	* Vic DHS - Eye injury - Flash burns (pdf)
	* Vic DHS - Eye injury - Foreign body (pdf)

introduction

	* patients with a possible open globe injury should be examined with e…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 10 Sep 2018 08:42:47 +0000</pubDate>
        </item>
        <item>
            <title>coronaviridae / corona viruses (CoV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=coronaviridae</link>
            <description>coronaviridae / corona viruses (CoV)

see also:

	* viruses
	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)

Introduction

	* single stranded enveloped RNA viruses with a very long RNA genome, coding up to 30 viral proteins. 
		*  four or five genes make infectious virus particles, but many others support diseases by modifying immune responses</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Jan 2026 08:53:32 +0000</pubDate>
        </item>
        <item>
            <title>corticosteroids</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=corticosteroids</link>
            <description>corticosteroids

also known as glucocorticosteroids

see also:

	* pharmacology main index
	* cortisol physiology
	* osteoporosis
	* Aust Prescr 2008 Corticosteroid-induced osteoporosis and fractures
	* Aust Presc 2007 - Evaluation of adrenocortical function in adults

systemic corticosteroids

	* corticosteroids may cause a potentially fatal hyperinfection or disseminated strongyloidiasis in those who have lived in the tropics and have possibly undiagnosed chronic infection</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Apr 2024 12:39:27 +0000</pubDate>
        </item>
        <item>
            <title>cortisol physiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cortisol</link>
            <description>cortisol physiology

see also:

	* adrenocorticotropic hormone (ACTH)
	* corticosteroids

Introduction

	* cortisol is a glucocorticoid hormone produced by the cortex of the adrenal glands and is a key component of the physiologic stress response

Biochemistry

	* cortisol is 11-beta,17-alpha,21-trihydroxypregn-4-ene-3,20-dione</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 23 Oct 2022 01:05:40 +0000</pubDate>
        </item>
        <item>
            <title>coryza / the common cold / viral rhinopharyngitis / rhinitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=coryza</link>
            <description>coryza / the common cold / viral rhinopharyngitis / rhinitis

see also:

	* viruses
	* influenza
	* rhinitis

introduction

	* the Common Cold or coryza is the most common infection to affect humans with adults having an average of 2-4 infections each year, and a child, 6-8 infections each year</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 06 Oct 2025 22:20:49 +0000</pubDate>
        </item>
        <item>
            <title>cor pulmonale</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cor_pulmonale</link>
            <description>cor pulmonale

see also:

	* congestive cardiac failure
	* the patient with swollen leg(s)

introduction

	* cor pulmonale is right sided cardiac failure due primarily to a pulmonary aetiology
	* accounts for ~7% of adult heart disease in western cultures and 10-30% of decompensated heart failure admissions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Jan 2014 07:23:06 +0000</pubDate>
        </item>
        <item>
            <title>co-trimoxazole</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cotrimoxazole</link>
            <description>co-trimoxazole

see also:

	* antibiotics
	* trimethoprim

	* the use of cotrimoxazole in elderly patients carries an increased risk of severe adverse reactions.
	* may not be tolerated well in patients with HIV / AIDS
	* do not use in those with G6PD deficiency as risk of haemolytic anaemia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 00:40:44 +0000</pubDate>
        </item>
        <item>
            <title>acute cough in the adult</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cough_adult_acute</link>
            <description>acute cough in the adult

see also:

	* the persistent cough
	* The child with a cough
	* stridor
	* wheeze

introduction

	* acute onset of coughing is one of the commonest causes of presentations to a doctor
	* in the non-asthmatic adult, it is most commonly due to acute bronchitis, influenza or coryza but there is a wide range of differentials</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 26 Sep 2020 23:06:32 +0000</pubDate>
        </item>
        <item>
            <title>The child with a cough</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cough_paed</link>
            <description>The child with a cough

see also:

	* croup
	* bronchiolitis
	* asthma
	* pneumonia
	* pertussis (whooping cough)
	* RCH guideline - cough
	* Aust Presc 2009 - cough and cold remedies for children:
		* nasal saline drops are effective for chronic rhinosinusitis
		* physiotherapy is only effective for cough due to suppurative lung disease
		* honey may help cough but should not be used in infants under 12 months age due to risk of infantile botulism</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 22 Oct 2009 06:04:39 +0000</pubDate>
        </item>
        <item>
            <title>the persistent cough</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cough_persistent</link>
            <description>the persistent cough

see also:

	* respiratory medicine
	* acute cough in the adult
	* The child with a cough

the adult with a persistent cough

differential diagnosis

	* post-viral cough
	* upper airway cough syndrome - usually associated with post-nasal drip
		* chronic sinusitis
		* allergic and other forms of rhinitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 09 Mar 2017 14:49:38 +0000</pubDate>
        </item>
        <item>
            <title>COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid-19</link>
            <description>COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)

see also:

	* coronaviridae / corona viruses (CoV)
	* influenza
	* viruses
	* pandemics - influenza, coronavirus, Ebola
	* pandemic transmission mitigation through public health measures
	* COVID-19 risk and benefit of vaccination
	* the unwell patient after Covid-19 vaccination
	* COVID-19 science
	* COVID-19 pandemic global timeline
	* Covid-19 in Australia
	* Covid-19 in Victoria
	* COVID-19 global deaths
	* COVID-19 point of care testing
	* COVI…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Feb 2026 01:56:25 +0000</pubDate>
        </item>
        <item>
            <title>COVID-19 risk and benefit of vaccination</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid-19_risk</link>
            <description>COVID-19 risk and benefit of vaccination

see also:

	* coronaviridae / corona viruses (CoV)
	* influenza
	* viruses
	* vaccines
	* pandemics - influenza, coronavirus, Ebola
	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* the unwell patient after Covid-19 vaccination
	* COVID-19 science
	* Covid-19 in Australia
	* Covid-19 in Victoria
	* &lt;https://www.sciencemag.org/collections/coronavirus&gt;
	* The Lancet's coronavirus archive
	* Aust Gov. patient handout of Pfizer vaccination
	* Aust. govt pa…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Nov 2025 10:00:52 +0000</pubDate>
        </item>
        <item>
            <title>Covid-19 in Australia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid19_australia</link>
            <description>Covid-19 in Australia

see also:

	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* Covid-19 in Victoria
	* Australian Health Protection Principal Committee (AHPPC) policy statements of Covid-19 management
	* National Plan to transition Australia's National Covid19 Response July 2021
		*  &gt; 70% adults double vax (expected by end of Oct 2021) =&gt; phase B
			*  ongoing low level local restrictions with lockdowns possible
			*  ease restrictions on those who are vaccinated
			*  increase internati…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 10 Jan 2024 00:59:35 +0000</pubDate>
        </item>
        <item>
            <title>COVID-19 global deaths</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid19_deaths</link>
            <description>COVID-19 global deaths

see also:

	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* pandemics - influenza, coronavirus, Ebola
	* pandemic transmission mitigation through public health measures
	* COVID-19 science
	* Covid-19 in Australia
	* Covid-19 in Victoria

Introduction

	* ascertaining the extent of deaths due to a pandemic is not easy for many reasons such as:
		*  many countries have pre-existing poor death registration systems
			*  these issues are exacerbated when death rates incre…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 05 Sep 2020 15:02:15 +0000</pubDate>
        </item>
        <item>
            <title>COVID-19 pandemic global timeline</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid19_global</link>
            <description>COVID-19 pandemic global timeline

see also:

	* coronaviridae / corona viruses (CoV)
	* influenza
	* viruses
	* pandemics - influenza, coronavirus, Ebola
	* pandemic transmission mitigation through public health measures
	* COVID-19 science
	* COVID-19 pandemic global timeline
	* Covid-19 in Australia
	* Covid-19 in Victoria
	* COVID-19 global deaths

Pandemic timeline

	* China implemented extremely stringent quarantine measures for its people which has also allowed other countries time to pre…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Dec 2022 00:43:30 +0000</pubDate>
        </item>
        <item>
            <title>COVID-19 health care worker testing</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid19_hcwtesting</link>
            <description>COVID-19 health care worker testing

see also:

	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* COVID-19 point of care testing
	* nasal and nasopharyngeal swabs
	* COVID-19 risk and benefit of vaccination

Introduction

	* whilst all HCWs in Australia will be required to be vaccinated for Covid-19, as the vaccination is imperfect (protection against transmissable Covid-19 infections is 60-80% depending upon age and time since vaccinated), HCW's are at risk of infection, especially if working…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 29 Sep 2021 01:55:22 +0000</pubDate>
        </item>
        <item>
            <title>COVID-19 point of care testing</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid19_poctesting</link>
            <description>COVID-19 point of care testing

see also:

	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* COVID-19 health care worker testing
	* nasal and nasopharyngeal swabs

Introduction

	* rapid point of care (POC) testing for Covid-19 is becoming more readily available in Australia, and as of Nov 1 2021, pending TGA approval home testing rapid antigen kits will become available</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 02 Oct 2021 03:36:42 +0000</pubDate>
        </item>
        <item>
            <title>COVID-19 science</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid19_science</link>
            <description>COVID-19 science

see also:

	* coronaviridae / corona viruses (CoV)
	* influenza
	* viruses
	* pandemics - influenza, coronavirus, Ebola
	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* COVID-19 risk and benefit of vaccination
	* Covid-19 in Australia
	* Covid-19 in Victoria
	* &lt;https://www.sciencemag.org/collections/coronavirus&gt;
	* The Lancet's coronavirus archive
	* &lt;https://dontforgetthebubbles.com/evidence-summary-paediatric-covid-19-literature/&gt;
	* NSW Govt's Critical Analysis Unit - EB…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 17 Dec 2025 07:09:01 +0000</pubDate>
        </item>
        <item>
            <title>the unwell patient after Covid-19 vaccination</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid19_vaxreactions</link>
            <description>the unwell patient after Covid-19 vaccination

see also:

	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* COVID-19 risk and benefit of vaccination
	* Aust Gov. patient handout of Pfizer vaccination
	* Aust. govt patient handout of AZ vaccination risks
	* SAFEVAC Adverse Reaction to Vaccines Reporting Process in Australia - note you should gain the patient's consent prior to reporting 

Introduction

	* by far the most common reactions to Covid-19 vaccinations are:
		*  vasovagal / anxiety wh…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 Dec 2021 10:28:16 +0000</pubDate>
        </item>
        <item>
            <title>Covid-19 in Victoria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid19_victoria</link>
            <description>Covid-19 in Victoria

see also:

	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* Covid-19 in Australia
	* Covid-19 management at Western Health
	* Covid-19 modeling for Victoria
	* &lt;https://www.covid19data.com.au/&gt;
		*  in Victoria:
			* Victorian DHHS government website on coronavirus
				* vulnerable patient planning - homelessness, disabled, mental health patients:
					*  &lt;https://fac.dhhs.vic.gov.au/covid-19-plan-disability-services-sector&gt;
					*  &lt;https://fac.dhhs.vic.gov.au/covid-19-…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Feb 2026 01:53:22 +0000</pubDate>
        </item>
        <item>
            <title>Covid-19 modeling for Victoria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid_vic_model</link>
            <description>Covid-19 modeling for Victoria

see also:

	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* Covid-19 in Australia
	* Covid-19 management at Western Health
	* Covid-19 in Victoria

Predictive modelling

	* modeling of pandemics has been well studied as per pandemic epidemiology

	* the problem with models is that even small changes in the quantity of a parameter or even the timing of a change to the effective R value via interventions can result in massive changes in predicted outcomes.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 20 Sep 2020 02:28:26 +0000</pubDate>
        </item>
        <item>
            <title>Covid-19 management at Western Health</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=covid_wh</link>
            <description>Covid-19 management at Western Health

see also:

	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* Covid-19 in Australia
	* Covid-19 in Victoria
		*  in Victoria:
			* Victorian DHHS government website on coronavirus
				* vulnerable patient planning - homelessness, disabled, mental health patients:
					*  &lt;https://fac.dhhs.vic.gov.au/covid-19-plan-disability-services-sector&gt;
					*  &lt;https://fac.dhhs.vic.gov.au/covid-19-family-and-community-services-0&gt;
					*  &lt;https://www.dhhs.vic.gov.au/m…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:49:42 +0000</pubDate>
        </item>
        <item>
            <title>cracked heels</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cracked_heels</link>
            <description>cracked heels

see also:

	* dermatology
	* hyperkeratosis / thickened skin / ichthyosis / lichenification

Introduction

	* cracked heels are common and can not only be a cosmetic issue, but can be painful and if severe deep fissures, can become a site for infection and cellulitis although this seems less common than would be expected due to the general superficial nature of the fissures, but in diabetics can also lead to diabetic foot ulcers</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Feb 2026 22:08:44 +0000</pubDate>
        </item>
        <item>
            <title>creatine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=creatine</link>
            <description>creatine

see also:

	* exercise for health
	* sarcopenia / generalised muscle wasting
	* diets and healthy foods

Introduction

	* creatine is a naturally occurring compound made from three amino acids: L-arginine, glycine, and L-methionine
	* the body primarily produces creatine in the liver, kidneys, and pancreas and hence is not an essential nutrient</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 08 Nov 2025 22:35:58 +0000</pubDate>
        </item>
        <item>
            <title>chronic renal failure</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=crf</link>
            <description>chronic renal failure

see also:

	* renal medicine (nephrology)
	* acute kidney injury (AKI) / acute renal failure (ARF)

Introduction

	* chronic kidney disease (CKD) is a common condition which may lead to chronic renal failure (CRF) and end-stage renal failure (ESRF) which may require dialysis or a renal transplant

aetiology of CRF</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 21 Jan 2026 00:02:14 +0000</pubDate>
        </item>
        <item>
            <title>cricothyroidotomy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cricothyroidotomy</link>
            <description>cricothyroidotomy

	* bougie-assisted cricothyrotomy
	* the surgical airway

Ram Parekh MD, performs a life-saving cricothyrotomy on a post-arrest patient:



introduction

	* surgical cricothyroidotomy is an emergency procedure to create a patent airway by creating a hole in the cricothyroid membrane and passing a tube such as an endotracheal tube to allow ventilation of a compromised airway.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 10 Dec 2022 05:37:27 +0000</pubDate>
        </item>
        <item>
            <title>critical care (intensive care medicine)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=critcare</link>
            <description>critical care (intensive care medicine)

see also:

	* CICM website
	* transfer of the critically ill adult patient
	* choking / respiratory arrest / cardiac arrest / BLS / ALS / CPR
	* assisted ventilation
	* Victorian REACH metropolitan critical care and mental health bed availability
	* Victorian Chris Critical Health Resource Information System critical care bed availability website
	* VicTAG register of life saving drugs in Victorian hospitals (pdf)
	* Australian Resuscitation Council
	* em…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 18 May 2021 00:20:29 +0000</pubDate>
        </item>
        <item>
            <title>transfer of the critically ill adult patient</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=critcare_transfers</link>
            <description>transfer of the critically ill adult patient

see also:

	* critical care (intensive care medicine)
	* emergency medical retrieval services for transfer of the critically ill
	* Dr Andrew Tagg's video tutorial on preparing for a safe transfer
	* Victorian metropolitan critical care bed availability
	* ACEM policy - Minimum standards for Transport of Critically Ill Patients (pdf)
	* ACEM policy - Minimum standards for the Intrahospital Transport of Critically Ill Patients (pdf)
	* Adult Retrieval…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jan 2015 13:27:33 +0000</pubDate>
        </item>
        <item>
            <title>Crohn's disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=crohns</link>
            <description>Crohn's disease

see also:

	* inflammatory bowel disease (IBD)
	* emedicine

introduction

	* 1st described by Crohn, Ginzberg, and Oppenheimerf in 1932.
	* it is thought that interplay between the gut’s bacteria and immune system responses are a critical step in developing Crohn’s Disease</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Jan 2026 22:30:07 +0000</pubDate>
        </item>
        <item>
            <title>croup</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=croup</link>
            <description>croup

see also paediatric emergency medicine

	* RCH guideline - croup (laryngotracheobronchitis)
	* NSW NETS - croup (pdf)
	* Dr Andrew Tagg's video tutorial on croup and bronchiolitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jan 2015 13:29:48 +0000</pubDate>
        </item>
        <item>
            <title>C reactive protein (CRP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=crp</link>
            <description>C reactive protein (CRP)

see also:

	* erythrocyte sedimentation rate (ESR)
	* full blood examination (FBE)
	* CRP - science and pathophysiology

Introduction

	* CRP was 1st described in 1930 by Tillet and Francis.
	* C-reactive protein plays a key role in the host's defence against infection by activating the complement system and acts as an opsonin for bacterial sequences and nuclear material which has been expressed from a cell during apoptosis, and thus enhances phagocytosis thereby helpin…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 07 Jan 2026 09:03:22 +0000</pubDate>
        </item>
        <item>
            <title>CRP - science and pathophysiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=crp_physiology</link>
            <description>CRP - science and pathophysiology

see also:

	* C reactive protein (CRP)
	* innate immunity

Introduction

	* C Reactive Protein is a key actor in the clearance of bacteria and dying cells and is an acute phase reactant with levels rising within 12 hours of most acute inflammatory states.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 30 Jul 2022 03:19:48 +0000</pubDate>
        </item>
        <item>
            <title>The crying or irritable baby</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=crying_baby</link>
            <description>The crying or irritable baby

	* RCH guideline - the crying baby</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 14:46:13 +0000</pubDate>
        </item>
        <item>
            <title>cryoglobulinaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cryoglobulinaemia</link>
            <description>cryoglobulinaemia

see also:

	* hypothermia
	* Raynaud's phenomenon
	* frostbite

Introduction

	* cryoglobulinemia is a rare condition in which those who have cryoglobulins (these immunoglobulin complexes typically precipitate at temperatures below 37degC and will dissolve again if the blood is heated) may develop serious complications when exposed to the cold.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Oct 2023 03:05:26 +0000</pubDate>
        </item>
        <item>
            <title>cerebrospinal fluid (CSF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=csf</link>
            <description>cerebrospinal fluid (CSF)

see also:

	* meningitis
	* subarachnoid haemorrhage (SAH)
	* lumbar puncture (LP)

introduction

	* CSF volume is 135-150ml and is produced at rate to ~500ml/day
	* 50-70% is formed from ependymal cells in the choroid plexus with remainder coming from blood vessels and the ventricle walls</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 06 Jul 2025 01:22:57 +0000</pubDate>
        </item>
        <item>
            <title>CT abdomen</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ctabdo</link>
            <description>CT abdomen

see also:

	* radiology
	* CT thorax / chest
	* CT brain
	* retroperitoneal fibrosis (RPF)

Interpretation of the CT abdomen scan

basic concepts

	* nearly all urologic calculi are radio-opaque on CT scan except for rare drug calculi (ciprofloxacin, indinavir, sulphonamides)
		* differentiate ureteric calculi from phleboliths by evidence of surrounding inflammation around the ureteric calculus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 16 Nov 2025 08:23:28 +0000</pubDate>
        </item>
        <item>
            <title>CT brain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ctbrain</link>
            <description>CT brain

see also:

	* radiology
	* arachnoid cysts
	* hydrocephalus

interpreting the CT brain

general concepts

	* is there any cerebral oedema, if so, what type and where?
	* is there evidence of a bleed, if so, what type of bleed, how old and where?
		* acute bleeds and clots are hyperdense</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Aug 2018 11:57:06 +0000</pubDate>
        </item>
        <item>
            <title>connective tissue (CT) disorders</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ctdisorders</link>
            <description>connective tissue (CT) disorders

see also:

	* collagen disorders
	* elastin disorders
	* joint hypermobility disorders and syndromes
	* Marfan's syndrome
	* Ehlers-Danlos syndrome
	* fibromuscular dysplasia (FMD)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Mar 2023 20:24:16 +0000</pubDate>
        </item>
        <item>
            <title>CT spine - cervical (Cx), thoracic (Tx) or lumbar (Lx)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ctspine</link>
            <description>CT spine - cervical (Cx), thoracic (Tx) or lumbar (Lx)

see also:

	* radiology
	* CT brain
	* cervical spine injury
	* thoracic spine trauma
	* lumbar spine trauma
	* the lumbosacral spine Xray
	* trauma



Interpretation of CT spine

basic concepts

	* 3 Denis spinal columns concept of spinal injury
		* initially was applied to thoracolumbar injuries in 1976 but is applicable to lower cervical injuries as well</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 24 Feb 2024 01:51:05 +0000</pubDate>
        </item>
        <item>
            <title>CT thorax / chest</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ctthorax</link>
            <description>CT thorax / chest

see also:

	* radiology
	* CT abdomen
	* CT brain

Interpretation of the CT thorax scan

basic concepts

	* aortic dissection
		* if you don't see a dissection flap, look hard for intramural haematoma or penetrating ulcer

	* trauma
		* diaphragm rupture (usually on the left) is easily missed, look carefully on coronal and sagittal images</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 07 Jul 2017 13:53:08 +0000</pubDate>
        </item>
        <item>
            <title>culturally intelligent leadership in EM</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=culture</link>
            <description>culturally intelligent leadership in EM

see also:

	* welcome to the OzEMedicine Wiki
	* ACEM resources on cultural competence
	* Australian indigenous cultural knowledge resource Healing Foundation

Introduction

	* cultural competence is not being an expert on cultures but rather a willingness to try to understand, respect and empathise with those from different cultural backgrounds</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 05 Dec 2024 04:46:25 +0000</pubDate>
        </item>
        <item>
            <title>Cushing's syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cushingssynd</link>
            <description>Cushing's syndrome

see also:

	* cortisol physiology
	* corticosteroids

Introduction

	* Cushing's syndrome is the clinical syndrome which results from prolonged high activity of glucorticoasteroid hormones

Clinical features

	*  characteristic redistribution of adipose tissues (eg. buffalo hump on the upper back)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 01 Jun 2019 06:24:28 +0000</pubDate>
        </item>
        <item>
            <title>the chest X-ray (CXR)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cxr</link>
            <description>the chest X-ray (CXR)

see also:

	* radiology
	* wikipedia - chest radiograph
	* CXR atlas
	* Emedicine chest imaging articles
	* Medical student CXR interpretation tutorial
	* RadiologyED.org resource library
	* LITFL's 150 top CXR cases/quizzes

reading a CXR

before you get started

	* optimise room lighting by turning off stray lights - unfortunately this is not likely to be possible in most ED's
	* check patient name and date of examination</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Nov 2020 23:54:00 +0000</pubDate>
        </item>
        <item>
            <title>cyanide poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cyanide</link>
            <description>cyanide poisoning

see also:

	* toxicology
	* metabolic acidosis
	* &lt;https://emergency.cdc.gov/agent/cyanide/basics/facts.asp&gt;

introduction

	* severe cyanide poisoning is a rare event in Western cultures
	* fire is the most common source of cyanide exposure in Western countries
		*  cyanide gas is less dense than air so it will rise</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Nov 2020 08:48:26 +0000</pubDate>
        </item>
        <item>
            <title>Cyanotic spells in children</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cyanotic_spells</link>
            <description>Cyanotic spells in children

	* congenital heart disease (CHD)
	* RCH guideline - cyanotic spells</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Sep 2009 03:35:42 +0000</pubDate>
        </item>
        <item>
            <title>cytokines</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cytokines</link>
            <description>cytokines

see also:

	* chemokines
	* autacoids
	* fever - the febrile response to infections
	* interleukin-6 (IL-6)
	* interleukin-1b (IL-1b)
	* immunology
	* innate immunity
	* adaptive immunity

introduction

	* cytokines are small proteins released by cells which act through binding to cell wall receptors and affect the behaviour of other cells and perhaps the same cell which are particularly important in the immune response but generally excludes growth factors, hormones,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Dec 2025 22:50:29 +0000</pubDate>
        </item>
        <item>
            <title>cytotoxic agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=cytotoxics</link>
            <description>cytotoxic agents

see also:

	* neoplasia / cancer / tumours
	* immunosuppressants

Introduction

	* cytotoxics are those medications and substances which kill cells - especially rapidly dividing cells such as epithelial, gastro-intestinal, haemopoietic and many cancer cells
	* hence they are commonly used in</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Jul 2025 01:17:15 +0000</pubDate>
        </item>
        <item>
            <title>acute coronary syndromes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_acs</link>
            <description>acute coronary syndromes

see also:

	* cardiology
	* ischaemic heart disease (IHD)
	* the adult patient with chest pain in the ED
	* Mx of possible acute coronary syndrome without ST elevation (NSTEACS)
	* cardiac stress testing
	* acute myocardial infarction (AMI/STEMI/NSTEMI)
	* EBM for interventions in acute coronary syndromes
	* historical perspectives and timelines on ischaemic heart disease including the major research trials
	* AFTB Lecture Notes - ACS I
	* ACS in the Elderly: Where the …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 02 Mar 2026 22:59:33 +0000</pubDate>
        </item>
        <item>
            <title>EBM for interventions in acute coronary syndromes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_acs_ebm</link>
            <description>EBM for interventions in acute coronary syndromes

see also:

	* cardiology
	* acute coronary syndromes
	* Evidence based medicine (EBM) evidence classes
	* historical perspectives and timelines on IHD including the major research trials

Evidence for interventions in pts with coronary syndromes:

out-of-hospital 12 lead ECG's:

Class I:

	* Patients with AMI receive an earlier diagnosis and faster treatment with fibrinolytic drugs in the ED when paramedics obtain a 12-lead ECG in the field and …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 27 Oct 2008 04:44:31 +0000</pubDate>
        </item>
        <item>
            <title>atrial fibrillation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_af</link>
            <description>atrial fibrillation

see also:

	* cardiology
	* cardiac arrhythmias
	* atrial flutter
	* aetiology and pathophysiology of atrial fibrillation
	* Pre-excitation syndrome such as WPW
	* see Detailed Mx of the patient with AF in the ED

Introduction

	* prevalence of AF in western countries is 1-4% with 70% of those with AF being aged &gt; 65yrs and incidence appears to be increasing worldwide due to improved detection 
	* it is a major risk factor for</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Feb 2026 05:39:17 +0000</pubDate>
        </item>
        <item>
            <title>Atrial flutter</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_aflutter</link>
            <description>Atrial flutter

see also: cardiology; cardiac arrhythmias; AF

Introduction:

	* clinically, atrial flutter is managed similarly as for Atrial Fibrillation with which it is often in association, although of the two, AF is 7-8x more common as a cause for admission.
	* often flutter is not as well tolerated as AF due to the rapid and often difficult to control ventricular rate, especially with minimal exertion.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 11 Sep 2025 11:32:22 +0000</pubDate>
        </item>
        <item>
            <title>aetiology and pathophysiology of atrial fibrillation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_af_aetiology</link>
            <description>aetiology and pathophysiology of atrial fibrillation

see also:

	* cardiology
	* cardiac arrhythmias
	* atrial flutter
	* atrial fibrillation
	* Pre-excitation syndrome such as WPW
	* see Detailed Mx of the patient with AF in the ED

Introduction

	* lifestyle interventions, including weight loss and improved physical activity, have been shown to decrease AF risk in obese individuals. 

Aetiology</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 16 Jun 2024 14:02:57 +0000</pubDate>
        </item>
        <item>
            <title>Detailed Mx of AF in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_af_mxdetails</link>
            <description>Detailed Mx of AF in the ED

see also:

	* AF main page
	* cardiology
	* cardiac arrhythmias
	* atrial flutter
	* calculators:
		* CHADS2 Score for Atrial Fibrillation Stroke Risk
		* CHA2DS2-VASc Score for Atrial Fibrillation Stroke Risk
		* ABCD2 Score for TIA

	* NICS care bundle of documents to assist in the ED management of TIA and stroke
	* AHA/ASA Guidelines - Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack
	* Eur. Heart J. 2012: 2012 focu…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 23 Oct 2024 00:11:47 +0000</pubDate>
        </item>
        <item>
            <title>choking / respiratory arrest / cardiac arrest / BLS / ALS / CPR</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_asystole</link>
            <description>choking / respiratory arrest / cardiac arrest / BLS / ALS / CPR

	* pulseless electrical activity (PEA)/(EMD)
	* VF
	* cardiac arrhythmias
	* bradycardia
	* anaesthetics
	* Resuscitation
	* paediatric resus. drugs
	* ILCOR website - resuscitation guidelines including new 2010 recommendations
	* Australian Resuscitation Council 
	* RCH guideline - paediatric resuscitation
	* RCH guideline - paediatric cardiac arrest algorithm
	* Probability of neurologic recovery post cardiac arrest - scoring too…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 12 Dec 2025 04:00:03 +0000</pubDate>
        </item>
        <item>
            <title>broad complex tachycardias</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_broadcomplextachy</link>
            <description>broad complex tachycardias

see also:

	* cardiac arrhythmias
	*  Narrow Complex Tachycardias and the DDx
	* Supraventricular tachycardia (SVT)
	* ventricular tachycardia (VT)
	* LITFL - Right Ventricular Outflow Tract Tachycardia (RVOT)
WPW

	* is it really a broad complex tachy?
		*  if there is at least one lead with narrow complexes then it is NOT a broad complex tachy as the appearance may be due to either:
			*  sinus tachy with large ST elevation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 04 May 2024 02:24:05 +0000</pubDate>
        </item>
        <item>
            <title>coronary artery bypass graft (CABG)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_cabg</link>
            <description>coronary artery bypass graft (CABG)

see also:

	* cardiology
	* intracoronary stents

introduction

	* CABG has been the traditional Rx for patients with amenable coronary occlusions and suitable operative candidates.
	* recently, the introduction of drug-eluting stents is increasingly challenging the role of CABG in patients suitable for stent and who are likely to tolerate and comply with long term antithrombotic medications such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Mar 2009 04:43:20 +0000</pubDate>
        </item>
        <item>
            <title>electric storm</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_electricstorm</link>
            <description>electric storm

see also:

	* broad complex tachycardias
	* torsade de pointes VT
	* ventricular fibrillation (VF)
	* The basics of reading an ECG
	* ventricular tachycardia (VT)
	* 2011: The Evaluation and Management of Electrical Storm

Introduction

	* generally defined by 3 or more sustained episodes of ventricular tachycardia (VT), torsade de pointes VT, ventricular fibrillation (VF), or appropriate shocks from an implantable cardioverter-defibrillator within 24 hours and typically have a p…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 09 Sep 2023 07:44:13 +0000</pubDate>
        </item>
        <item>
            <title>genetic determinants of cardiac phenotypes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_genetics</link>
            <description>genetic determinants of cardiac phenotypes

see also:

	* cardiology

Introduction

	* a study of AI analysis of GWAS and cardiac indices was published in March 2024 which revealed a range of genetic associations including 40 new loci associations, a sub-group of these are outlined below.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 11 Mar 2024 22:02:07 +0000</pubDate>
        </item>
        <item>
            <title>Narrow complex tachycardias</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_narrowcomplextachy</link>
            <description>Narrow complex tachycardias

see also:

	* cardiac arrhythmias
	*  Broad Complex Tachycardias and the DDx
	* Supraventricular tachycardia (SVT) for Mx of acute paroxysmal SVT

DDx of narrow complex tachycardias:

	* tip: measure rate by counting number of QRS on the rhythm strip section of ECG and multiply by 6
	* if QRS duration is &lt; 120ms, then it is almost always a SVT rather than a</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Oct 2023 13:47:22 +0000</pubDate>
        </item>
        <item>
            <title>Mx of possible acute coronary syndrome without ST elevation (NSTEACS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_nsteacs_mx</link>
            <description>Mx of possible acute coronary syndrome without ST elevation (NSTEACS)

see also:

	* the adult patient with chest pain in the ED
	* acute coronary syndromes
	* acute myocardial infarction (AMI/STEMI/NSTEMI)
	* cardiac stress testing
	* cardiac markers (troponin)

introduction

	* this assumes the patient has had consideration of other aetiologies of chest pain as per the adult patient with chest pain in the ED and there is no new LBBB or ST elevation on ECG (see</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 May 2024 01:13:17 +0000</pubDate>
        </item>
        <item>
            <title>risk assessment of possible acute coronary syndrome without ST elevation (NSTEACS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_nsteacs_risk</link>
            <description>risk assessment of possible acute coronary syndrome without ST elevation (NSTEACS)

see also:

	* Mx of possible acute coronary syndrome without ST elevation (NSTEACS)
	* the adult patient with chest pain in the ED
	* ACS rule out algorithm for the adult patient with chest pain in the ED
	* acute coronary syndromes
	* acute myocardial infarction (AMI/STEMI/NSTEMI)
	* cardiac stress testing
	* cardiac markers (troponin)

introduction

	* one of the major difficulties for clinicians is deciding wh…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 09 Nov 2017 05:01:11 +0000</pubDate>
        </item>
        <item>
            <title>pulseless electrical activity (PEA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_pea</link>
            <description>pulseless electrical activity (PEA)

see also:

	*  cardiology
	*  choking / respiratory arrest / cardiac arrest / BLS / ALS / CPR
	*  also called Electro-Mechanical Dissociation (EMD)
	* paediatric resus. drugs
	* RCH guideline - paediatric cardiac arrest algorithm

Imminent predictors of PEA / cardiac arrest

	* It appears that rapid elevations in pulmonary pressures (due to pulmonary vascular bed compression such as in  mucus plug and massive aspiration, and acute hypoxic vasoconstriction) an…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 28 Jun 2020 01:37:08 +0000</pubDate>
        </item>
        <item>
            <title>cardiac physiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_physiol</link>
            <description>cardiac physiology

see also:

	* cardiology

Introduction

	* the heart is a 4 chamber pump which beats due to electrical impulses generated in the sino-atrial node in the right atrium which pass to the AV node then down the bundle of His, and then spreads out in a wave to excite myocardial fibres in the ventricles</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 09 Sep 2023 10:36:24 +0000</pubDate>
        </item>
        <item>
            <title>pre-excitation syndromes including WPW</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_preexcitation</link>
            <description>pre-excitation syndromes including WPW

see also:

	*  cardiology
	*  cardiac arrhythmias
	*  supraventricular tachycardias (SVT)
	*  atrial fibrillation
	*  &lt;https://litfl.com/pre-excitation-syndromes-ecg-library/&gt;

introduction

	* pre-excitation occurs when some portion of the ventricles are activated by an impulse from the atria sooner than expected if passing down a normal pathway.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 05 May 2024 00:42:40 +0000</pubDate>
        </item>
        <item>
            <title>premature ventricular contractions (PVCs) and bigeminy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_pvc</link>
            <description>premature ventricular contractions (PVCs) and bigeminy

see also:

	* cardiology
	* cardiac arrhythmias

introduction

	* a premature ventricular contraction or ventricular ectopic beat is a cardiac contraction that is generally premature or occurs before the expected sinus QRS complex and arises out of the ventricular tissue.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 03 Feb 2024 11:57:40 +0000</pubDate>
        </item>
        <item>
            <title>sinus tachycardia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_sinus_tachycardia</link>
            <description>sinus tachycardia

see also:

	* cardiology
	* supraventricular tachycardias (SVT)
cardiac output = stroke volume x heart ratemean arterial blood pressure = cardiac output x systemic vascular resistance
	* fall in systemic vascular resistance (eg. vasodilator drugs, ethanol, warm skin such as after a bath)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:31:45 +0000</pubDate>
        </item>
        <item>
            <title>intracoronary stents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_stents</link>
            <description>intracoronary stents

see also:

	* cardiology
	* coronary artery bypass graft (CABG)

introduction

1st generation bare metal stents

	* the first generation Palmaz-Schatz bare metal (BMS) coronary stents were evaluated in two major trials in 1994 (STRESS and Benestent):
		* angiographic restenosis rates at 6months were ~1/3rd less than for PTCA alone.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Mar 2009 04:42:13 +0000</pubDate>
        </item>
        <item>
            <title>cardiac stress ECG testing</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_stressecg</link>
            <description>cardiac stress ECG testing

see also:

	* Mx of possible acute coronary syndrome without ST elevation (NSTEACS)
	* cardiac stress testing

introduction

	* the low sensitivity and specificity of stress ECG testing for detection of significant coronary artery disease has resulted in it largely being displaced by other methods of cardiac stress testing

consider the patient's pre-test probability before stress testing</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 01 Aug 2013 07:21:58 +0000</pubDate>
        </item>
        <item>
            <title>cardiac stress testing</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_stress_testing</link>
            <description>cardiac stress testing

see also:

	* Mx of possible acute coronary syndrome without ST elevation (NSTEACS)
	* cardiac stress ECG testing

introduction

	* the sensitivity of the various modalities of stress testing is generally low, identifying less than half of those who will go on to have a further adverse cardiac event
	* the problem arises from the fact that, unlike as is the case with stable angina where there is a chronic limitation to coronary blood flow, patients with ACS tend to have a…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 20 Aug 2020 14:43:11 +0000</pubDate>
        </item>
        <item>
            <title>supraventricular tachycardias (SVT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_svt</link>
            <description>supraventricular tachycardias (SVT)

see also:

	*  cardiology
	*   cardiac arrhythmias
	*    Narrow Complex Tachycardias and the DDx
	*  paediatric supraventricular tachycardias (SVT)

see  Am. College Card Guidelines on Mx of SVT, RCH guideline - paediatric SVT

	* do not try DC reversion for multifocal atrial tachyardia (MAT) or sinus tachycardia - give IV fluids instead!

acute reversion of paroxysmal SVT:

haemodynamically unstable</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Oct 2023 13:49:12 +0000</pubDate>
        </item>
        <item>
            <title>paediatric supraventricular tachycardias (SVT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_svt_paed</link>
            <description>paediatric supraventricular tachycardias (SVT)

see also:

	*  cardiology
	*   cardiac arrhythmias
	*    Narrow Complex Tachycardias and the DDx
	*  supraventricular tachycardias (SVT)

see  Am. College Card Guidelines on Mx of SVT, RCH guideline - paediatric SVT

introduction

	* 70-90% of SVT in infants is AVRT and many infant SVTs are due to presence of accessory pathways which close after age 2 yrs as the heart develops</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 13 Apr 2014 12:01:40 +0000</pubDate>
        </item>
        <item>
            <title>torsade de pointes VT</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_torsadevt</link>
            <description>torsade de pointes VT

see also:

	* cardiac arrhythmias
	* ventricular tachycardia (VT)
	* LITFL - a case of prolonged QTc with R on T bigeminy leading to torsades

ref: EMedicine article on torsade de pointes

introduction:

	* torsade is an inherently unstable rhythm and will either revert or degenerate to VF, thus commence Rx as soon as it is recognised.
	* Most (75-82%) torsade de pointes (TDP) rhythms are started by a pause. Pacing at rates up to 140 bpm may prevent the ventricular pauses …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 Aug 2014 11:04:44 +0000</pubDate>
        </item>
        <item>
            <title>ventricular fibrillation (VF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_vf</link>
            <description>ventricular fibrillation (VF)

see also:

	* BLS and ALS for Mx of cardiac arrest
	* ventricular tachycardia (VT)
	* return of spontaneous circulation (ROSC) post-arrest

introduction

	* VF is most likely to occur in the ischaemic heart with either electrolyte imbalance, local acidosis or sympathetic stimulation (hence the obsession with electrolytes, rest, stress reduction and early commencement of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 04 Sep 2025 23:10:27 +0000</pubDate>
        </item>
        <item>
            <title>ventricular tachycardia (VT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=c_vt</link>
            <description>ventricular tachycardia (VT)

see also:

	* broad complex tachycardias
	* torsade de pointes VT
	* ventricular fibrillation (VF)
	* The basics of reading an ECG
	* electric storm</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 09 Sep 2023 06:45:06 +0000</pubDate>
        </item>
        <item>
            <title>dabigatran</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dabigatran</link>
            <description>dabigatran

see also:

	* Detailed Mx of AF in the ED
	* anticoagulants
	* idarucizumab (Praxbind)

introduction

	* Dabigatran is a potent, competitive and reversible direct thrombin inhibitor and is thus used as an oral anticoagulant for prevention of deep venous thrombosis (DVT) and new studies seem to show that it is more effective, and safer than warfarin for preventing stroke in patients with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:49:54 +0000</pubDate>
        </item>
        <item>
            <title>D-Dimer pathology test</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ddimer</link>
            <description>D-Dimer pathology test

see also:

	*  Ix of PE
	*   pathology
	*  age-adjusted D-Dimer cut-off values
	*   Wikipedia

	* a raised D-Dimer test does NOT mean there is a clot - there are many other causes of a raised D-Dimer - even just the normal inflammatory response following a vaccination or a bruise!

the D-Dimer test</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Jan 2026 07:23:57 +0000</pubDate>
        </item>
        <item>
            <title>deafness / hearing loss</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=deafness</link>
            <description>deafness / hearing loss

see also:

	* sensorineural hearing loss / deafness
	* ears, nose and throat surgery (ENT)
	* ED Mx of vertigo and BPV
	* tinnitus
	* RVEEH clinical practice guidelines:
		* Idiopathic Sudden Sensorineural Hearing Loss (pdf)
		* Impacted Wax (pdf)


introduction

	* deafness is classified as either conductive or sensorineural hearing loss / deafness or mixed and these are generally differentiated at the bedside by using Rinne and Weber tuning fork tests:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Oct 2018 03:35:28 +0000</pubDate>
        </item>
        <item>
            <title>sensorineural hearing loss / deafness</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=deafness_sensorineural</link>
            <description>sensorineural hearing loss / deafness

see also:

	* deafness / hearing loss
	* presbycusis (deafness of aging)
	* drug induced ototoxicity
	* endolymphatic hydrops including Meniere's disease

physiology

	* humans can detect sounds in a frequency range from about 20 Hz to 20 kHz
		*  infants can actually hear frequencies slightly higher than 20 kHz, but lose some high-frequency sensitivity as they mature</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Nov 2025 22:38:31 +0000</pubDate>
        </item>
        <item>
            <title>death and the potentially dead</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=death</link>
            <description>death and the potentially dead

see also:

	* the deceased patient in the ED
	* end of life care
	* how to verify death
	* verification of brain death in the ventilated patient
	* reportable and reviewable deaths - deaths which MUST be reported to the Coroner
	* how to complete a death certificate for cause of death
	* preparing for the worst - making life easier for your loved ones if you become critically ill or die
	* on the death of your loved one - estate issues and more

“Death is nothing …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 21 Mar 2020 01:23:48 +0000</pubDate>
        </item>
        <item>
            <title>verification of brain death in the ventilated patient</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=death_brain</link>
            <description>verification of brain death in the ventilated patient

see also:

	* death and the potentially dead
	* how to verify death
	* reportable and reviewable deaths - deaths which MUST be reported to the Coroner
	* how to complete a death certificate for cause of death
	* the comatose patient
	* post-coma unresponsiveness (persistent vegetative state)

verification of brain death in the ventilated patient

	* while the definition of brain death is largely a matter of legal statute, the law does not sp…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 05 Oct 2023 03:04:22 +0000</pubDate>
        </item>
        <item>
            <title>how to complete a death certificate for cause of death</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=death_certify</link>
            <description>how to complete a death certificate for cause of death

see also:

	* death and the potentially dead
	* how to verify death
	* reportable and reviewable deaths - deaths which MUST be reported to the Coroner
	* Western Health policies index for the deceased patient (intranet only)
		* Western Health's stillbirth and neonatal death procedure (pdf)
		* Western health's procedure for organ donation after cardiac death (pdf)
		* Western Health's post mortem request flow chart (pdf)


non-reportable d…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 May 2019 06:13:34 +0000</pubDate>
        </item>
        <item>
            <title>reportable and reviewable deaths - deaths which MUST be reported to the Coroner</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=death_coroners</link>
            <description>reportable and reviewable deaths - deaths which MUST be reported to the Coroner

see also:

	* death and the potentially dead
	* how to verify death
	* how to complete a death certificate for cause of death
	* when are doctors required to compulsorily report patients in Australia
	* Victorian Coroners Court Website
		* Victorian Coroner's publication - Coroners Process - Information for families and friends (PDF 3.14MB)

	* National Coroners' Information System (NCIS)
		* nation-wide centralised…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Feb 2026 01:57:35 +0000</pubDate>
        </item>
        <item>
            <title>on the death of your loved one - estate issues and more</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=death_estatemx</link>
            <description>on the death of your loved one - estate issues and more

see also:

	* preparing for the worst - making life easier for your loved ones if you become critically ill or die

Introduction

	* the death of a loved one, no matter how expected it may be is always traumatic, highly emotional times and a prolonged period of grief and the grieving process should be expected and support should be sought from grief counseling services, GP, friends or relatives as you feel necessary</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 04 Apr 2020 04:52:40 +0000</pubDate>
        </item>
        <item>
            <title>preparing for the worst - making life easier for your loved ones if you become critically ill or die</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=death_prepare</link>
            <description>preparing for the worst - making life easier for your loved ones if you become critically ill or die

see also:

	* on the death of your loved one - estate issues and more

Introduction

	* none of us want to come to the realisation of our own mortality, but avoiding the issue may only make our suffering more prolonged and make it harder for our loved ones to manage</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Apr 2020 11:57:32 +0000</pubDate>
        </item>
        <item>
            <title>how to verify death</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=death_verify</link>
            <description>how to verify death

see also:

	* death and the potentially dead
	* the deceased patient in the ED
	* verification of brain death in the ventilated patient
	* reportable and reviewable deaths - deaths which MUST be reported to the Coroner
	* how to complete a death certificate for cause of death

legal definition of death in Australia

	* a person is dead when there is irreversible cessation of circulation of blood in the body of the person, OR, irreversible cessation of function of the brain o…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Aug 2013 14:16:48 +0000</pubDate>
        </item>
        <item>
            <title>the deceased patient in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=deceased_in_ed</link>
            <description>the deceased patient in the ED

see also:

	* death and the potentially dead
	* end of life care
	* medico-legal issues in the ED
	* Western Health policies index for the deceased patient (intranet only)
		* Western Health's Death of a patient procedure (pdf)
		* Western Health's post mortem request flow chart (pdf)
		* Western health's procedure for organ donation after cardiac death (pdf)


introduction

	* from the medico-legal viewpoint for ED doctors there are 3 scenarios:
		* deceased pati…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Aug 2013 14:18:12 +0000</pubDate>
        </item>
        <item>
            <title>neuropsychology of decision making</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=decision_making</link>
            <description>neuropsychology of decision making

see also:

	* regret and regret avoidance and decision making
	* clinical decision making

introduction

	* the dopamine-basal ganglia and OFC-amygdala neural pathways of regret play an important role in adaptive behaviour and decision making
	* genomic MRI studies appear to show:
		* those who were better at being able to imagine their competitor's thinking and anticipate and respond to the actions of others (belief learning) had a variation in three genes th…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Jun 2014 08:49:32 +0000</pubDate>
        </item>
        <item>
            <title>clinical decision making</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=decision_making_clinical</link>
            <description>clinical decision making

see also:

	* neuropsychology of decision making
	* clinical decision support systems (CDSS)
	* Clinical Decision Making in Emergency Medicine - Prof. Patrick Croskerry - ICEM 2012 webcast

how does a clinician make a clinical decision

	* before we can develop computerised CDSS's we should first look at the cognitive processes that clinicians use to come to a decision whether it be on provisional diagnosis, an investigation or a management option.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Jun 2014 07:36:30 +0000</pubDate>
        </item>
        <item>
            <title>defensins</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=defensins</link>
            <description>defensins

see also:

	* innate immunity

Introduction

	* defensins are small antimicrobial cysteine-rich cationic proteins
	* they play an important role in innate immunity against viruses, Gram-positive and Gram-negative bacteria, and parasites in the digestive system and the reproductive system</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 09 Jul 2025 04:46:33 +0000</pubDate>
        </item>
        <item>
            <title>dehydration</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dehydration</link>
            <description>dehydration

see also:

	* RCH guideline - dehydration in children
	* intravenous (iv) fluids</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 29 Jun 2016 06:21:04 +0000</pubDate>
        </item>
        <item>
            <title>dementia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dementia</link>
            <description>dementia

see also:

	* neurology
	* Mental state - delirium vs dementia vs psychosis
	* cognition
	* Behavioural and Psychological Symptoms of Dementia (BPSD)

introduction

	* dementia is a serious loss of cognitive ability in a previously unimpaired person, beyond what might be expected from normal aging.
	* affected areas of cognition may be memory, attention, language, and problem solving.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 22 Feb 2026 23:25:52 +0000</pubDate>
        </item>
        <item>
            <title>dengue fever</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dengue_fever</link>
            <description>dengue fever

see also:

	* the febrile returned traveller
	* viruses

introduction

	* flaviviral mosquito-borne (Aedes albopictus and A. aegypti) illness of the tropics including northern Queensland
	* these mosquitoes usually live between the latitudes of 35° North and 35° South below an elevation of 1,000 metres (although in Mexico and Sth American tropics have been found up 2200m but the mosquitoes are rare higher than 1700m) where average winter isotherms are above 10degC</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 22 Mar 2025 09:05:58 +0000</pubDate>
        </item>
        <item>
            <title>dental</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dental</link>
            <description>dental

see also:

	* dental injuries
	* acute dental pain / dental abscess
	* dental caries
	* gingivitis
	* periodontitis
	* mouthwashes
	* faciomaxillary
	* dental physiology
	* RCH guideline - paed. dental problems
	* RCH info - Dental services for children in Victoria
	* 24hr emergency dental services by appointment only in Melbourne (incl. public holidays):
		* Contempo Healthcare Dental Surgery - ph: 0421 983 283
			* 387 Barry Rd, Broadmeadows 03 9357 7050 or 508 Grimshaw St Bundoora 03 …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Aug 2025 03:24:16 +0000</pubDate>
        </item>
        <item>
            <title>dental caries</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dental_caries</link>
            <description>dental caries

see also:

	* dental
	* periodontitis
	* acute dental pain / dental abscess
	* odontogenic sinusitis

Introduction

	* dental decay has been linked to duration of exposure to sweet and acid foods such as:
		* sweetened drinks including fruit juice, cordial, Milo, Quik, Ribena, sports drinks, soft drinks (including sugar-free)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2024 04:52:51 +0000</pubDate>
        </item>
        <item>
            <title>dental injuries</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dental_injuries</link>
            <description>dental injuries

see also dental, faciomaxillary

	* RCH guideline - dental injuries
	* Wikipedia - general information on teeth and tooth structure
	* drbunn.com - tooth numbering systems
	* dental anaesthesia
	* The Royal Dental Hospital of Melbourne

FDI Two-digit tooth numbering system



dental injuries

	* all pts with significant dental trauma should be advised that any teeth involved may later die &amp; require root canal Rx

concussed tooth

	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 06 Aug 2021 23:38:41 +0000</pubDate>
        </item>
        <item>
            <title>acute dental pain / dental abscess</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dental_pain</link>
            <description>acute dental pain / dental abscess

see also:

	* dental injuries
	* dental
	* dental caries
	* mouthwashes
	* faciomaxillary
	* RCH guideline - paed. dental problems

	* if looking for a localised dental abscess or mandibular injury then OPG is the usual preferred investigation
	* if there is swelling in the floor of the mouth or the neck then a CT scan should be considered to exclude an abscess such as in Ludwig's angina</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 18 Nov 2025 22:24:23 +0000</pubDate>
        </item>
        <item>
            <title>dental physiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dental_physiology</link>
            <description>dental physiology

see also:

	* dental

Introduction

	* most vertebrate groups have the ability to replace their teeth. 
		* mammals have two sets of teeth: primary and adult teeth
		* some animals such as mouse incisors, grow continuously throughout their life time as a result of active somatic stem cells at the proximal end of the incisor tooth combined with roles of a range of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Aug 2025 06:42:29 +0000</pubDate>
        </item>
        <item>
            <title>depression</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=depression</link>
            <description>depression

see also:

	* psychiatry and mental health
	* antidepressants
	* suicide
	* Geriatric depression scale
	* stress
	* happiness
	* sadness
	* loneliness
	* new screening tool for depression in Australian indigenous peoples - the aPHQ-9

Other references

	* Aust Presc 2008 - Rx of perinatal depression (post-partum)
	* Aust Presc 2007 - Antidepressants in pregnancy and breastfeeding

In the news

	* Dec 2008 - Antidepressants the most common PBS prescription for women aged 28-33yrs in A…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 08 Apr 2025 00:17:27 +0000</pubDate>
        </item>
        <item>
            <title>dermatitis herpetiformis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dermatitis_herpetiformis</link>
            <description>dermatitis herpetiformis

see also:

	* dermatology
	* dermnetnz

introduction

	* rare, chronic pruritic papulo-vesicular auto-immune skin disorder mainly occurring in people with coeliac disease which accounts for 80% of cases, other associations not related to gluten intolerance include:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 05 Jul 2019 13:40:17 +0000</pubDate>
        </item>
        <item>
            <title>dermatology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dermatology</link>
            <description>dermatology

see also:

	* psoriasis
	* mouth ulcers
	* papular rashes
	* pustular rashes
	* the petechial rash / purpura
	* the linear skin lesion or rash
	* facial rashes
	* acute generalized non-vesicular non-purpuric rashes covering most parts of the body
	* skin nodular &quot;rash&quot;
	* scalp folliculitis
	* acne rosacea
	* atopic eczema
	* seborrheic dermatitis
	* blepharitis / dry eyes
	* angular cheilitis (cracked corners of the mouth)
	* xanthelasma
	* madarosis (loss of eyebrows)
	* alopecia
…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Feb 2026 22:10:28 +0000</pubDate>
        </item>
        <item>
            <title>dermatomyositis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dermatomyositis</link>
            <description>dermatomyositis

see also:

	* myopathy / myositis / muscle aches and pains
	* polymyositis (PM)
	* inclusion body myositis (IBM)

introduction

	* a connective-tissue disease related to polymyositis (PM) that is characterized by inflammation of the muscles and the skin
	* may also affect the joints, the esophagus, the lungs, and, less commonly, the heart
	* ~100-200 cases per million</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 21 Oct 2013 04:36:13 +0000</pubDate>
        </item>
        <item>
            <title>EM in developing countries</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=developing_countries</link>
            <description>EM in developing countries

see also:

	* ACEM International Medicine Special Interest Group
		* includes reports on Emergency Medicine in Papua New Guinea

	* WHO Child and Adolescent Health programs and documentation
		* WHO Pocket Book - Guidelines for the management of common illnesses with limited resources
			* International Child Health Review Collaboration (ICHRC.org) - collaborative development of Pocket Book guidelines and EBM
			* ICHRC Emergency Triage Assessment and Treatment (ETAT)…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Jun 2009 06:06:50 +0000</pubDate>
        </item>
        <item>
            <title>comparison of developmental disorders affecting social development</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dev_disorders</link>
            <description>comparison of developmental disorders affecting social development

see also:

	* autism spectrum disorder (ASD)
	* attention deficit hyperactivity disorder (ADHD)
 feature  autism  Asperger's  ADHD  Williams-Beuren syndrome (WBS)  impaired social interactions  non-verbal cues, reciprocity, social isolation  awkwardness, odd, non-verbal cues, display of empathy, social isolation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 06 Sep 2012 08:25:13 +0000</pubDate>
        </item>
        <item>
            <title>Diabetes insipidus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diabetes_insipidus</link>
            <description>Diabetes insipidus

	* RCH guideline - diabetes insipidus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 14:56:23 +0000</pubDate>
        </item>
        <item>
            <title>the diabetic foot - infection or foot ulcers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diabetic_foot</link>
            <description>the diabetic foot - infection or foot ulcers

see also:

	* cellulitis
	* sepsis / septicaemia
	* diabetes mellitus
	* venous leg ulcers
	* WH policy - diabetic foot infections (doc) - intranet only
		* At WH, these patients are generally referred to Diabetes Fooot Service, endocrinology and vascular surgery which are based at Footscray Hospital (NOT Sunshine Hospital)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 May 2017 07:13:29 +0000</pubDate>
        </item>
        <item>
            <title>the dialysis patient in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dialysis_patient</link>
            <description>the dialysis patient in the ED

see also:

	* suspected peritonitis in peritoneal dialysis patients
	* antibiotic doses for peritoneal dialysis patients
	* Western Health renal medicine policies and procedures
	* kidney.org.au
	* Aust Presc 2007 - Prescribing in renal disease
	* WH Mx of blocked haemodialysis access - intranet only

introduction

	* the dialysis patient presents unique complexities to ED staff and early discussion with a renal team is advisable.
	* many peripheral hospitals have…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Apr 2022 04:54:45 +0000</pubDate>
        </item>
        <item>
            <title>antibiotic doses for peritoneal dialysis patients</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dialysis_peritoneal_ab_doses</link>
            <description>antibiotic doses for peritoneal dialysis patients

see also:

	* suspected peritonitis in peritoneal dialysis patients
	* antibiotics
empirically increased by 25%
Intraperitoneal Dosing of Antibiotics in Continuous Ambulatory Peritoneal Dialysis
    Intermittent    Continuous      (once daily unless otherwise specified)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Jan 2012 23:23:07 +0000</pubDate>
        </item>
        <item>
            <title>suspected peritonitis in peritoneal dialysis patients</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dialysis_peritonitis</link>
            <description>suspected peritonitis in peritoneal dialysis patients

see also:

	* spontaneous bacterial peritonitis (SBP)
	* renal medicine (nephrology)
	* antibiotic doses for peritoneal dialysis patients
	* Western Health renal medicine policies and procedures
	* ISPD Peritonitis Recommendations: 2016 Update on Prevention and Treatment

introduction

	* patients on peritoneal dialysis are at risk of life threatening peritonitis
	* early recognition and Rx is important and peritonitis should be suspected if…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 17 Apr 2019 09:36:51 +0000</pubDate>
        </item>
        <item>
            <title>diarrhoea</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diarrhoea</link>
            <description>diarrhoea

see also:

	* gastroenteritis
	* The child with gastroenteritis
	* traveller's diarrhoea
	* food poisoning
	* osmotic diarrhoea from excessive solutes:
		*  ingestion of too much solutes which either cannot be absorbed or exceed the capacity for absorption
		*  eg. lactose, fructose, aspartame, saccharine, sorbitol, laxatives</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 27 Jan 2020 01:58:16 +0000</pubDate>
        </item>
        <item>
            <title>chronic diarrhoea</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diarrhoea_chronic</link>
            <description>chronic diarrhoea

see also:

	* diarrhoea
	* Clinical Gastroenterology and Hepatology 2017: Chronic Diarrhea: Diagnosis and Management (pdf)

Introduction

	* Chronic diarrhoea is defined by duration of &gt;4 weeks
	* 5% will develop an episode of chronic diarrhoea some time in their life
	* Failure to make a diagnosis is more likely due to overlooking a common cause than missing a rare cause of chronic diarrhoea</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Jul 2025 07:52:36 +0000</pubDate>
        </item>
        <item>
            <title>post-prandial diarrhoea</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diarrhoea_postprandial</link>
            <description>post-prandial diarrhoea

see also:

	* diarrhoea
	* irritable bowel syndrome (IBS)
	* colorectal cancer (bowel cancer)
	* diverticulitis

introduction

aetiology

	* irritable bowel syndrome (IBS)
		* may be helped by chronic chilli ingestion to desensitize receptors 
		* “Habba syndrome” - dysfunctional gallbladder 
			* may be helped by bile acid binding agents such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 19 May 2016 00:20:54 +0000</pubDate>
        </item>
        <item>
            <title>diazepam</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diazepam</link>
            <description>diazepam

see also benzodiazepines, anticonvulsants, sedatives, hypnotics and anxiolytics, induction agents

Summary

	* 99% prot. bound;  enterohep. circ; metab. to nordazepam -&gt; oxazepam;
	* T½= 30-60hrs; Vd = 1.1L/kg;  Clearance = 0.38ml/min/kg;
	* redistribution half-times: diazepam 1hr;

Clinical usage and dosages

Anticonvulsant</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 31 Oct 2009 22:47:39 +0000</pubDate>
        </item>
        <item>
            <title>disseminated intravascular coagulation (DIC)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dic</link>
            <description>disseminated intravascular coagulation (DIC)

see also:

	* coagulation pathways

Introduction

	* DIC is a rare but serious condition that causes a consumptive widepread clotting process throughout the circulation and thus also results in bleeding tendency due to the consumption of clotting factors</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Oct 2021 03:58:04 +0000</pubDate>
        </item>
        <item>
            <title>dicloxacillin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dicloxacillin</link>
            <description>dicloxacillin

see also:

	* penicillins
	* antibiotics for Rx of Staph. aureus

	* avoid prolonged courses, particularly in the elderly as risk of cholestatic jaundice, even though risk is half that for flucloxacillin
	* not for use in neonates - see PI

introduction

	* dicloxacillin is a narrow spectrum penicillin active against Gram +ves including St. aureus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 09 Jan 2012 04:01:35 +0000</pubDate>
        </item>
        <item>
            <title>diets and healthy foods</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diets</link>
            <description>diets and healthy foods

see also:

	* healthy living and diets
	* foods that may be toxic or bad for you
	* FODMAPs and the low FODMAP diet
	* salt / sodium in food products
	* honey
	* creatine
	* milk and dairy products
	* atherosclerosis and primary prevention
	* 2019 Lancet commission into best diet for health and environment
	* 2024: Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet

	* accurate evidence…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 Mar 2026 11:05:48 +0000</pubDate>
        </item>
        <item>
            <title>digoxin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=digoxin</link>
            <description>digoxin

see also:

	* digoxin toxicity/overdose
	* AF
	* pharmacology main index
	* cardiology
	* cardiac arrhythmias

introduction:

	* digoxin is a cardiac glycoside used in the treatment of most types of cardiac failure and supraventricular dysrhythmias.

Dosing in adults

rapid digitalisation for Mx of RAF in adults

usual dosing</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 23 Oct 2024 00:10:12 +0000</pubDate>
        </item>
        <item>
            <title>diphtheria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diphtheria</link>
            <description>diphtheria

	* see also:
		*  clinically important bacteria
		*  vaccines


Introduction

	* an potentially life threatening infection caused by the bacterium Corynebacterium diphtheriae which produces the diphtheria toxin that causes the main symptoms
	* thanks to widespread vaccination of children with diphtheria vaccines (combined with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Jun 2025 05:29:43 +0000</pubDate>
        </item>
        <item>
            <title>diplopia / double vision</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diplopia</link>
            <description>diplopia / double vision

see also:

	* ophthalmology

Introduction

	* this is a very common symptom
	* the clinician needs to determine if it is monocular or binocular

Aetiology

monocular diplopia

	* ie. double vision with one eye closed
	* keratoconus
	* astigmatism</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 10 Sep 2018 09:02:29 +0000</pubDate>
        </item>
        <item>
            <title>disaster medicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=disaster_medicine</link>
            <description>disaster medicine

see:

	* Victorian State health emergency response plan (SHERP)
	* emergency medical retrieval services for transfer of the critically ill
	* radiation emergencies
	* disaster medical aspects for Melbourne
	* ACEM paper - disaster medical services (pdf)
	* ACEM paper - Disposition of Patients in the Emerg. Dept.on Notification of a Mass Casualty Incident (pdf)
	* ACEM paper - Infectious Disease and Biohazard Exposure in the Emergency Department (pdf)
	* Simon Bolch's Fellowshi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 27 May 2025 14:55:22 +0000</pubDate>
        </item>
        <item>
            <title>disaster medical aspects for Melbourne</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=disaster_melbourne</link>
            <description>disaster medical aspects for Melbourne

	* see also:
		*  disaster medicine
		*  Australian Disaster Resilience knowledge hub
		*  Aust. Govt. Geoscience Australia natural hazards and community safety


Introduction

	* Melbourne is relatively fortunate it is itself in a fairly low risk region for natural disasters with the most frequent events being:
		* bushfires and grassfires are common events but are generally confined to more rural areas and Melbourne itself is unlikely to be directly impa…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Feb 2026 13:24:43 +0000</pubDate>
        </item>
        <item>
            <title>vertebral osteomyelitis / discitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=discitis</link>
            <description>vertebral osteomyelitis / discitis

see also:

	* epidural abscess

Introduction

	* infection of the intervertebral discs is a potentially serious problem with a risk of sepsis / septicaemia and spread to form ostemyelitis or epidural abscess and then irreversible neurology or worse.

Aetiology

	* most cases are haematogenous spread following bacteraemic episodes:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 08 Aug 2018 09:15:07 +0000</pubDate>
        </item>
        <item>
            <title>Disclaimer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=disclaimer</link>
            <description>Disclaimer

This information is provided by the authors of OzEMedicine in good faith and they attempt to ensure it is up to date and accurate. 



FIRST DO NO HARM

Use of this wiki information is at your own risk





This wikipedia does NOT represent the views of, nor is it necessarily endorsed by government bodies, health services nor the ACEM, but is content created in good faith by Australian emergency physicians.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 12 Jul 2013 04:57:32 +0000</pubDate>
        </item>
        <item>
            <title>Diffuse idiopathic skeletal hyperostosis (DISH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dish</link>
            <description>Diffuse idiopathic skeletal hyperostosis (DISH)

see also:

	* acute thoracic back pain in the adult
	* ankylosing spondylitis (AS)

Introduction

	* Diffuse idiopathic skeletal hyperostosis is a degenerative condition of the thoracic spine in older adults characterized by undulating “osteophytic-like” bone formation along the anterior longitudinal ligament and sometimes the posterior longitudinal ligament, which may lead to partial or complete fusion of adjacent spinal levels.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 05 Apr 2020 04:02:17 +0000</pubDate>
        </item>
        <item>
            <title>internal carotid artery dissection</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dissection_carotid</link>
            <description>internal carotid artery dissection

see also:

	* stroke (CVA)

introduction

	* carotid dissection is an uncommon event occurring in ~2 in 100,000 population per annum
	* along with vertebral artery dissection, it accounts for ~20% of ischaemic stroke (CVA) in young adults
	* most common age is the mid-forties</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 May 2014 06:01:45 +0000</pubDate>
        </item>
        <item>
            <title>vertebral artery dissection</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dissection_vertebral</link>
            <description>vertebral artery dissection

see also:

	* stroke (CVA)
	* vertebral artery aneurysm

introduction

	* vertebral artery dissection is an uncommon event occurring in ~1 in 100,000 population per annum
	* along with internal carotid artery dissection, it accounts for ~20% of ischaemic stroke (CVA) in young adults
	* most common age is the early forties</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 24 Apr 2019 23:38:53 +0000</pubDate>
        </item>
        <item>
            <title>diuretics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diuretics</link>
            <description>diuretics

see also pharmacology main index, hypertension, congestive cardiac failure

History of diuretic use:

	* Use of mercurials to Rx syphilis &amp; their common diuretic side effect led to the use of mercurial diuretics in 1920's &amp; despite toxicity, these potent loop diuretics dominated Rx of CCF until advent of modern loop diuretics.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 21 Jan 2009 02:35:31 +0000</pubDate>
        </item>
        <item>
            <title>loop diuretics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diuretics_loop</link>
            <description>loop diuretics

see also:

	*  diuretics
	*  congestive cardiac failure

Introduction

	* More rapid onset, shorter action &amp; more potent diuresis than thiazides &amp; thus greater homeostatic responses;
	* Loop diuretics are organic anions that circulate bound to proteins (&gt;90%), limiting their Vd, and do not enter tubular fluid by means of glomerular filtration but, rather, require secretion across proximal tubular cells, through organic anion transporters (OAT1 and OAT2) and the multidrug resistan…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 04 Dec 2017 06:53:24 +0000</pubDate>
        </item>
        <item>
            <title>Osmotic diuretics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diuretics_osmotic</link>
            <description>Osmotic diuretics

see also diuretics, head_injury, glaucoma

Osmotic Diuretics:

	* Must be:
		* freely filtered by glomerulus;
		* limited reabsorption in tubule;
		* relatively inert;
		* given in sufficiently large doses to incr. osmol. of plasma &amp; glom.filtrate;

	* Result in:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Oct 2008 07:17:09 +0000</pubDate>
        </item>
        <item>
            <title>Thiazide diuretics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diuretics_thiazides</link>
            <description>Thiazide diuretics

see also:

	*  diuretics
	*  gout
	*  hypertension

Introduction

	* Benzothiadiazides were synthesised in attempt to enhance potency of carbonic anhydrase inhibitors but an unanticipated chemical reaction led to substances that increased chloride excretion &amp; thus had a different effect to</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 06:47:07 +0000</pubDate>
        </item>
        <item>
            <title>diverticulitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=diverticulitis</link>
            <description>diverticulitis

see also:

	* the patient with acute abdominal pain in the ED

introduction

	* diverticula are herniations of the mucosa and submucosa or the entire wall thickness through the muscularis and in Western cultures, 95-95% involve the sigmoid colon, while in those living in Africa and Asia, prevalence is only 0.2% of the population and it mainly affects the right side!</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jul 2023 03:51:00 +0000</pubDate>
        </item>
        <item>
            <title>diabetes mellitus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dm</link>
            <description>diabetes mellitus

see also:

	* endocrinology
	* Mx of 1st presentation diabetes mellitus
	* Mx of the diabetic patient in ED
	* insulin
	* DDx of hyperglycaemia
	* oral hypoglycaemic agents
	* metformin
	* hypoglycaemia
	* diabetic ketoacidosis
	* diabetes mellitus in children
	* risk factors and aetiology of diabetes mellitus

Other references

	* JAMA 2008: Does This Patient With Diabetes Have Osteomyelitis of the Lower Extremity?(pdf)
	* Aust Presc 2008 - Preventing foot ulcers
	* MJA 2008 …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 09 Aug 2025 10:31:14 +0000</pubDate>
        </item>
        <item>
            <title>Mx of 1st presentation diabetes mellitus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dm_1stdxmx</link>
            <description>Mx of 1st presentation diabetes mellitus

see also:

	* endocrinology
	* diabetes mellitus
	* Mx of the diabetic patient in ED
	* insulin
	* DDx of hyperglycaemia
	* oral hypoglycaemic agents
	* metformin
	* hypoglycaemia
	* diabetic ketoacidosis
	* diabetes mellitus in children
	* risk factors and aetiology of diabetes mellitus

Introduction

	* this is a brief outline of initial ED Mx of an adult patient found to have a high blood glucose

Initial Ix in ED of adults

	* usual ABC's of ED - mov…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Oct 2025 01:02:38 +0000</pubDate>
        </item>
        <item>
            <title>risk factors and aetiology of diabetes mellitus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dm_aetiology</link>
            <description>risk factors and aetiology of diabetes mellitus

see also:

	* diabetes mellitus

type 2 diabetes mellitus

introduction

	* type 2 diabetes (T2D) is a complex metabolic disease associated with:
		* obesity (BMI &gt; 120% of ideal) - 90% are obese
		* age &gt; 45yrs 
		* energy dense diets may be an independent risk factor</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 May 2016 03:34:57 +0000</pubDate>
        </item>
        <item>
            <title>diabetic ketoacidosis (DKA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dm_dka</link>
            <description>diabetic ketoacidosis (DKA)

see also:

	* SGLT2 inhibitor induced diabetic ketoacidosis (gliflozin DKA)
	* diabetes mellitus
	* endocrinology
	* insulin
	* hypoglycaemia
	* hyperosmolar hyperglycaemic state (HSS or HONK)
	* diabetes mellitus in children
	* Western Health procedures (intranet only):
		* Insulin infusion (docx)
		* Initial Management of Hyperosmolar Hyperglycamic State (doc)
		* initial Mx of diabetic ketoacidosis (DKA) (doc)

	* AFTB lectures - DKA
	* RCH - Mx of DKA in children…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Jan 2023 23:37:47 +0000</pubDate>
        </item>
        <item>
            <title>SGLT2 inhibitor induced diabetic ketoacidosis (gliflozin DKA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dm_dka_sglt2</link>
            <description>SGLT2 inhibitor induced diabetic ketoacidosis (gliflozin DKA)

see also:

	* diabetic ketoacidosis (DKA)
	* oral hypoglycaemic agents
	* gliflozins / SGLT2 inhibitors

Introduction

	* until the introduction of SGLT2 inhibitors (gliflozins), diabetic ketoacidosis (DKA) only occurred in type I insulin-dependent diabetic patients
	* these agents have been shown to cause a potentially life threatening euglycaemic form of diabetic ketoacidosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 01 Oct 2023 16:27:46 +0000</pubDate>
        </item>
        <item>
            <title>hyperosmolar hyperglycaemic state (HSS or HONK)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dm_hhs</link>
            <description>hyperosmolar hyperglycaemic state (HSS or HONK)

see also:

	* DDx of hyperglycaemia
	* diabetic ketoacidosis (DKA)
	* diabetes mellitus
	* insulin
	* Western Health procedures (intranet only):
		* Insulin infusion (docx)
		* Initial Management of Hyperosmolar Hyperglycamic State (doc)
		* initial Mx of diabetic ketoacidosis (DKA) (doc)


introduction

	* formerly known as hyperosmolar non-ketotic coma (HONK)
	* type 2 diabetic patients who become unstable for a period of days can develop a seve…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 May 2015 15:31:28 +0000</pubDate>
        </item>
        <item>
            <title>Mx of the diabetic patient in ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dm_mx</link>
            <description>Mx of the diabetic patient in ED

see also:

	* endocrinology
	* diabetes mellitus
	* insulin
	* DDx of hyperglycaemia
	* oral hypoglycaemic agents
	* metformin
	* hypoglycaemia
	* diabetic ketoacidosis
	* diabetes mellitus in children

Introduction

	* diabetes mellitus is an important co-morbidity factor for patients presenting to the ED, particularly, if they are type 1 insulin dependent diabetics as these patients often have their basal insulin requirements forgotten raising the risk of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 09 Aug 2025 11:29:34 +0000</pubDate>
        </item>
        <item>
            <title>diabetes in children</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dm_paed</link>
            <description>diabetes in children

see also:

	* paediatric emergency medicine
	* endocrinology
	* diabetes mellitus
	* insulin
	* hypoglycaemia
	* Mx of diabetes in children going to theatre for surgery
	* RCH - Mx of DKA in children
	* RCH guideline - Mx of diabetes phone calls</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 17 Apr 2014 05:55:17 +0000</pubDate>
        </item>
        <item>
            <title>Mx of diabetes in children going to theatre for surgery</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dm_paed_theatre</link>
            <description>Mx of diabetes in children going to theatre for surgery

see also:

	* paediatric emergency medicine
	* endocrinology
	* diabetes mellitus
	* insulin
	* hypoglycaemia
	* diabetes in children
	* RCH guideline - diabetes mellitus
	* RCH guideline - diabetes and surgery

introduction

	* primary aims for Mx of diabetic children going to theatre for surgery and who are thus fasting are:
		* maintainence of euglycaemia, and,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 17 Apr 2014 05:50:49 +0000</pubDate>
        </item>
        <item>
            <title>DNA and genes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dna</link>
            <description>DNA and genes

see also:

	* genetics
	* genomics
	* gene regulation
	* micro RNAs (miRNAs)

Introduction

	* the human genome consists of over three billion nucleotide pairs which make up the 46 chromosomes in each nucleated cell
		* an average chromosome contains 130 million nucleotide pairs which if put into a line would be 4cm long!</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jan 2026 22:58:49 +0000</pubDate>
        </item>
        <item>
            <title>DOACs / NOACs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=doacs</link>
            <description>DOACs / NOACs

see also:

	* anticoagulation

Introduction

	* direct acting oral anticoagulants

Examples

	*  rivaroxaban 
			*  edoxaban
			*  apixaban 
			*  dabigatran</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 05 May 2018 04:23:32 +0000</pubDate>
        </item>
        <item>
            <title>dobutamine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dobutamine</link>
            <description>dobutamine

see also:

	* inotropes
	* sympathomimetics
	* Western Health policy - Dobutamine hydrochloride (intranet only)

introduction

	* inotrope with vasodilatation
	* primarily used in refractory heart failure or cardiogenic shock but avoided a sole agent in septic shock due to the risk of hypotension from the vasodilatation.
	* unlike dopamine, it does not selectively cause renal vasodilatation.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Jan 2012 02:07:41 +0000</pubDate>
        </item>
        <item>
            <title>domestic violence</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=domestic_violence</link>
            <description>domestic violence

see also:

	* psychiatry and mental health
	* managing violence or the aggressive patient in the ED
	* cultural issues in domestic violence
	* sexual assault / rape
	* non-fatal suffocation or strangulation
	* Domestic Violence Resource Centre Victoria

introduction

	* domestic / family violence is a crime in Australia
	* it has many layered factors which contribute to this complex issue however much is being done to reduce this and fortunately, Victoria has amongst the lowes…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 May 2024 01:34:41 +0000</pubDate>
        </item>
        <item>
            <title>cultural issues in domestic violence</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=domestic_violence_cultural</link>
            <description>cultural issues in domestic violence

see also:

	* domestic violence
	* India's dowry and how it may contribute to domestic violence in Indian families living in Australia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 May 2014 01:31:06 +0000</pubDate>
        </item>
        <item>
            <title>domperidone (Motilium)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=domperidone</link>
            <description>domperidone (Motilium)

	* use of domperidone is associated with increased risk of serious ventricular arrythmias and sudden cardiac death, particularly in adults aged greater than 60 years taking daily doses greater than 30mg
	* initiate Rx at the lowest effective dose</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 14 Dec 2012 05:28:16 +0000</pubDate>
        </item>
        <item>
            <title>dopamine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dopamine</link>
            <description>dopamine

see also:

	* sympathomimetics
	* inotropes

History:

	* The naturally occurring immediate precursor of noradrenaline;
	* was once used for cardiogenic shock with renal hypoperfusion;
	* was once used to counteract renal &amp; mesenteric vasoconstriction with alpha-adrenergic doses adrenaline &amp; noradrenaline;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Jan 2012 04:04:01 +0000</pubDate>
        </item>
        <item>
            <title>dopamine receptor blockers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dopamine_blockers</link>
            <description>dopamine receptor blockers

see also:

	* sympathomimetics
	* dopamine
	* dopamine receptors

introduction

	* dopamine receptors in the brain and autonomic ganglia are vital for a wide range of neurologic functions and are involved in the extrapyramidal movement control system, pleasure reward systems, modulation of autonomic system and prolactin secretion</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 May 2014 08:07:00 +0000</pubDate>
        </item>
        <item>
            <title>dopamine receptors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dopamine_receptors</link>
            <description>dopamine receptors

see also:

	* sympathomimetics
	* dopamine
	* dopamine receptor blockers

introduction

	* dopamine is a sympathomimetic amine which is an important endogenous neurotransmitter and sympathetic hormone
	* dopamine is removed from the synapse by dopamine transporter (DAT)
		* DAT is inhibited by many recreational drugs such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 May 2014 08:01:41 +0000</pubDate>
        </item>
        <item>
            <title>doxycycline</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=doxycycline</link>
            <description>doxycycline

see also:

	* antibiotics
	* tetracycline antibiotics

introduction

	* a tetracycline class bacteriostatic antibiotic
	* active against a wide range of Gram positive and Gram negative organisms, Chlamydia, Mycoplasma, Rickettsiae, Borrelia, syphilis, N. gonorrhoeae, pre-erythrocytic and asexual bloodstages of Plasmodium falciparum
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 31 Dec 2013 06:10:51 +0000</pubDate>
        </item>
        <item>
            <title>DPP-1 inhibitors / Cathepsin C inhibitors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dpp1inhib</link>
            <description>DPP-1 inhibitors / Cathepsin C inhibitors

see also:

	* bronchiectasis

Introduction

	* dipeptidyl peptidase-1 (DPP-1) inhibitors (aka Cathepsin C inhibitors) are the first disease-specific therapy shown to be effective in non-cystic fibrosis bronchiectasis
	* DPP-1 plays a crucial role in activating various granular serine proteases including cathepsin G (CatG), neutrophil elastase (NE) and proteinase 3 (PR3)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Jan 2026 20:50:11 +0000</pubDate>
        </item>
        <item>
            <title>droperidol (Droleptan)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=droperidol</link>
            <description>droperidol (Droleptan)

see also:

	* anti-psychotic medications

introduction

	* droperidol is a butyrophenone type antipsychotic agent which is similar to haloperidol
	* it produces marked tranquillization and sedation as well as having an anti-emetic effect
	* it potentiates other CNS depressants
	* also produces mild alpha-adrenergic blockade, peripheral vascular dilatation,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 May 2014 06:34:18 +0000</pubDate>
        </item>
        <item>
            <title>Near drowning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=drowning</link>
            <description>Near drowning

	* RCH guideline - near drowning</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 14:54:13 +0000</pubDate>
        </item>
        <item>
            <title>doctor's bag pharmaceutical supplies</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=drsbag</link>
            <description>doctor's bag pharmaceutical supplies

see also:

	* welcome to the OzEMedicine Wiki

Introduction

	* Australian doctors are able to obtain certain pharmaceuticals for emergency use for patients free of charge
	* see &lt;https://www.pbs.gov.au/browse/doctorsbag&gt;
	* the doctor wll need to order a Prescriber Bag Supply Order Book</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 12 Feb 2025 01:27:06 +0000</pubDate>
        </item>
        <item>
            <title>Drug calculations</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=drugcalculations</link>
            <description>Drug calculations

see also pharmacology main index

Drug dose calculators

	* RCH guideline - IV fluids
	* RCH paediatric emergency drug dose calculator
	* Cornell Uni Pediatric medical calculators
	* RCH paediatric drug doses
	* RCH therapeutic drug level monitoring guidelines (pdf)

Basic calculations:

	* 1% = 10mg/ml; 
	* 1:1000 = 1mg/ml; 
	* 1:10,000 = 0.1mg/ml = 100mcg/ml;

Convert mcg/kg/min to ml/hr:

	* [volume in flask(mls)/amount in flask(mcg)] x mcg/kg/min x weight(kg) x 60</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:56:37 +0000</pubDate>
        </item>
        <item>
            <title>drug dependency</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=drug_dependency</link>
            <description>drug dependency

see also:

	* Addiction medicine - drug and alcohol - main index and links
	* ethanol/alcohol dependence
	* opiate and opioid dependence
	* acute pain Mx in drug dependent patients
	* pain, analgesia and analgesics
	* marijuana / cannabis / THC
	* volatile substance abuse
	* ecstasy
	* amphetamines and related psychostimulant substances
	* cocaine
	* gamma hydroxybutyrate (GHB)
	* hallucinogens
	* Medical Practitioners Board of Victoria - article on the Drugs, Poisons &amp; Controll…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Dec 2015 02:31:38 +0000</pubDate>
        </item>
        <item>
            <title>credentialling and performance appraisals of senior doctors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dr_credentialing</link>
            <description>credentialling and performance appraisals of senior doctors

see also:

	* medical professionalism
	* Vic. DOH clinical engagement and credentialling of senior doctors
		* Vic DOH credentialling toolkit
		* Partnering for performance guide (375kb, pdf)
		* Information for senior doctors (170kb, pdf)
		* Tips and checklists for senior doctors (170kb, pdf)
		* Senior doctor, management and organisational competencies (227kb, pdf)

	* Western health policies (intranet only):
		* Managing Underperfo…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2013 05:16:08 +0000</pubDate>
        </item>
        <item>
            <title>antibodies to double stranded DNA (dsDNA / anti-DNA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dsdna</link>
            <description>antibodies to double stranded DNA (dsDNA / anti-DNA)

see also:

	* arthritis - clinical patterns

introduction

	* the anti-double stranded DNA (anti-dsDNA) blood test is used to help diagnose systemic lupus erythematosus (SLE) in a person who has a positive result on a test for anti-nuclear antibodies (ANA) and has clinical signs and symptoms that suggest lupus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Dec 2015 04:23:49 +0000</pubDate>
        </item>
        <item>
            <title>delayed sequence induction</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dsi</link>
            <description>delayed sequence induction

see also:

	* emergency intubation

Introduction

	* A modification to usual RSI where procedural sedation is given to permit optimal pre-oxygenation
		* Ketamine is the prototypical agent used
		* Published by Weingart
		* A useful option in critically ill patients who are difficult to pre-oxygenate (ie due to agitation)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 22 Jan 2019 07:22:31 +0000</pubDate>
        </item>
        <item>
            <title>Dupuytren's contracture</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dupuytrens</link>
            <description>Dupuytren's contracture

see also:

	* rheumatology
	* eye color phenotypes and disease associations

Introduction

	* a painless common benign fibroproliferative disorder that leads to the formation of the collagen knots and fibres in the palmar fascia which leads to progressive flexion deformity of the fingers (sparing the thumb and forefinger) in older people generally over the age of 50yrs</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 13 Oct 2024 14:26:00 +0000</pubDate>
        </item>
        <item>
            <title>cerebral dural venous sinus thrombosis (CVST)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dural_sinus_thrombosis</link>
            <description>cerebral dural venous sinus thrombosis (CVST)

see also:

	* headache

Introduction

	* thrombosis of the cerebral venous sinus is a rare, potentially life threatening condition which causes raised intracranial pressure (ICP)
	* adult prevalence is 3-16 cases per million population per year with 75% being female and mainly in young adults, presumably due to pregnancy and</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 19 Jun 2025 08:09:10 +0000</pubDate>
        </item>
        <item>
            <title>deep venous thrombosis (DVT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt</link>
            <description>deep venous thrombosis (DVT)

see also:

	* DVT prophylaxis
	* DVT prophylaxis for the surgical patient
	* DVT prophylaxis, anticoagulation and spinal anaesthesia or spinal cord injured patients
	* Ix of suspected pulmonary embolism (PE)
	* Mx of suspected DVT
	* Mx of lower limb DVT
	* Rx of venous thrombosis (DVT/PE) and superficial thrombophlebitis - American College of Chest Physicians guidelines 2012
	* DVT and post-thrombotic syndrome (PTS)
	* upper limb DVT
	* thrombophlebitis
	* thrombop…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 17 Apr 2025 00:12:20 +0000</pubDate>
        </item>
        <item>
            <title>Mx of suspected DVT</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_dx</link>
            <description>Mx of suspected DVT

see also:

	* Mx of lower limb DVT
	* deep venous thrombosis (DVT)
	* upper limb DVT
	* Ix of suspected pulmonary embolism (PE)

Mx of suspected DVT in ED:

	* patient should be briefly assessed for:
		* other differentials
			* the patient with swollen leg(s)

		* presence of risk factors
			*  traditional risk factors
				*  cancer (including polycythaemia rubra vera), pelvic mass, hormonal Rx, recent surgery/immobilisation, pregnancy, PH or FH DVT/PE,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 08 Sep 2025 12:12:42 +0000</pubDate>
        </item>
        <item>
            <title>Mx of lower limb DVT</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_mx</link>
            <description>Mx of lower limb DVT

see also:

	* Rx of venous thrombosis (DVT/PE) and superficial thrombophlebitis - American College of Chest Physicians guidelines 2012
	* deep venous thrombosis (DVT)
	* Mx of suspected DVT
	* upper limb DVT
	* Mx of PE
	* guidelines on starting anticoagulation and warfarin Rx
	* AFTB lectures - venous thromboembolism
	* DVT prophylaxis
	* thrombophlebitis

	* for unprovoked DVT:
		* thrombophilia blood testing should NOT be done until at least 2 weeks after ceasing anticoa…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Mar 2026 04:57:57 +0000</pubDate>
        </item>
        <item>
            <title>Ix of suspected pulmonary embolism (PE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_pe_ix</link>
            <description>Ix of suspected pulmonary embolism (PE)

see also:

	* pulmonary embolism (PE)
	* Mx of confirmed PE
	* deep venous thrombosis (DVT)
	* Mx of suspected DVT
	* V/Q ventilation-perfusion lung scans
	* template to assist in the discharge documentation of suspected PE SSU admits
	* MJA 2007: simplifying the Dx of PE
	* AFTB lectures - venous thromboembolism
	* Two-level Well's score for DVT/PE
	* 2017: PE and syncope - the maths - D-Dimer or no D-Dimer?
	* see AHA 2026: 2026 AHA/ACC/ACCP/ACEP/CHEST/…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2026 02:42:26 +0000</pubDate>
        </item>
        <item>
            <title>DVT prophylaxis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_proph</link>
            <description>DVT prophylaxis

see also:

	* Mx of lower limb DVT
	* deep venous thrombosis (DVT)
	* risk assessment for venous thromboembolism (VTE)
	* DVT prophylaxis, anticoagulation and spinal anaesthesia or spinal cord injured patients
	* DVT prophylaxis for the surgical patient
	* DVT_proph_nonsurg
	* DVT, PE, VTE prophylaxis and risk assessment in patients with lower leg immobilization (eg BKPOP plaster for fracture ankle)
	* NHMRC NICS Stop The Clot patient information brochure (pdf)
	* NSW Govt: VTE …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:57:05 +0000</pubDate>
        </item>
        <item>
            <title>DVT prophylaxis, anticoagulation and spinal anaesthesia or spinal cord injured patients</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_proph_neuro</link>
            <description>DVT prophylaxis, anticoagulation and spinal anaesthesia or spinal cord injured patients

see also:

	* DVT prophylaxis
	* risk assessment for venous thromboembolism (VTE)
	* Western Health DVT prophylaxis and anticoagulation guidelines including peri-operative Mx of those patients on warfarin (pdf) - intranet only

DVT prophylaxis for spinal cord injury patients

	* Consider prophylaxis 
	* must discuss with trauma and/or neurosurgery units</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 28 Jan 2011 03:46:04 +0000</pubDate>
        </item>
        <item>
            <title>DVT, PE, VTE prophylaxis and risk assessment in patients with lower leg immobilization (eg ...</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_proph_pop</link>
            <description>DVT, PE, VTE prophylaxis and risk assessment in patients with lower leg immobilization (eg BKPOP plaster for fracture ankle)

see also:

	* DVT prophylaxis
	* ankle injuries and fractures
	* risk assessment for venous thromboembolism (VTE)
	* DVT / VTE risk assessment scores and tools

Introduction

	* the clinical risk benefit analysis of DVT, PE, VTE prophylaxis in adult patients with a lower limb immobilization due to requirement of a BK POP or similar for a fractured ankle or foot is complic…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:56:46 +0000</pubDate>
        </item>
        <item>
            <title>DVT prophylaxis for the surgical patient</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_proph_surg</link>
            <description>DVT prophylaxis for the surgical patient

see also:

	* main DVT prophylaxis page including details of mechanical methods of prophylaxis
	* risk assessment for venous thromboembolism (VTE)
	* DVT prophylaxis, anticoagulation and spinal anaesthesia or spinal cord injured patients
	* Western Health DVT prophylaxis and anticoagulation guidelines including peri-operative Mx of those patients on warfarin (pdf) - intranet only

As at 2010 for Western Health:

DVT prophylaxis in the adult general surgi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 28 Jan 2011 03:45:44 +0000</pubDate>
        </item>
        <item>
            <title>DVT and post-thrombotic syndrome (PTS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_pts</link>
            <description>DVT and post-thrombotic syndrome (PTS)

see also:

	* Rx of venous thrombosis (DVT/PE) and superficial thrombophlebitis - American College of Chest Physicians guidelines 2012
	* deep venous thrombosis (DVT)
	* venous insufficiency of the leg

introduction

	* PTS is a cluster of leg symptoms and signs attributable to previous DVT. 
	* PTS occurs in about one-third of patients after acute DVT and up to two-thirds who have had an iliofemoral DVT</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Aug 2013 08:06:07 +0000</pubDate>
        </item>
        <item>
            <title>risk assessment for venous thromboembolism (VTE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_risk</link>
            <description>risk assessment for venous thromboembolism (VTE)

see also:

	* DVT prophylaxis
	* see also DVT / VTE risk assessment scores and tools

VTE risk assessment for patients being admitted to hospital

high risk

	* surgery for THR, TKR, or hip fracture
	* abdominal or pelvic surgery for cancer
	* multiple major trauma injuries</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 24 Jul 2025 01:09:41 +0000</pubDate>
        </item>
        <item>
            <title>DVT / VTE risk assessment scores and tools</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_risk_scores</link>
            <description>DVT / VTE risk assessment scores and tools

	* see also:
		*  risk assessment for venous thromboembolism (VTE)
		*  DVT prophylaxis
		*  DVT, PE, VTE prophylaxis and risk assessment in patients with lower leg immobilization (eg BKPOP plaster for fracture ankle)


Caprini RAM score

	* originally designed for surgical inpatients
	* BUT was UNABLE to identify a subset of non-ICU medical inpatients who would benefit from pharmacologic prophylaxis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 06 May 2018 07:03:35 +0000</pubDate>
        </item>
        <item>
            <title>Rx of venous thrombosis (DVT/PE) and superficial thrombophlebitis - American College of Chest ...</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_rx_amcchp2013</link>
            <description>Rx of venous thrombosis (DVT/PE) and superficial thrombophlebitis - American College of Chest Physicians guidelines 2012

see also:

	* thrombophlebitis
	* Mx of lower limb DVT

	* this is a brief summary - please see the full detailed original recommendations published in American College of Chest Physicians guidelines 2012 in Chest - Volume 141, Issue 2 Suppl (February 2012) 
	*  2016 American College of Chest Physicians guidelines available here:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 22 May 2018 00:01:51 +0000</pubDate>
        </item>
        <item>
            <title>upper limb DVT</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dvt_upperlimb</link>
            <description>upper limb DVT

see also:

	* deep venous thrombosis (DVT)
	* DVT prophylaxis
	* Mx of lower limb DVT

introduction

	* ~10% of all cases of deep venous thrombosis (DVT) involve the upper extremity resulting in an annual incidence in USA of 0.4-1 cases per 10,000 people
	* cases have become more common with use of central venous catheters, cardiac pacemakers and defibrillators</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 07 Apr 2013 02:40:46 +0000</pubDate>
        </item>
        <item>
            <title>dysautonomia syndromes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dysautonomia</link>
            <description>dysautonomia syndromes

more information:

	* other causes of autonomic dysfunction and references
	* other causes of sinus tachycardia
	* Dr Fogoros' web page
	* The importance of exercise in these conditions - Arthritis Victoria fact sheet
	* this is NOT familial dysautonomia which is an exceedingly rare condition which only affects those of Ashkenazi Jew parentage.

introduction

	* a variably accepted collection of syndromes which mainly occurs in young women</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:43:22 +0000</pubDate>
        </item>
        <item>
            <title>dyschesia (painful defecation)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dyschesia</link>
            <description>dyschesia (painful defecation)

see also:

	* anal fissure
	* perianal abscess
	* anal fistula / fistula-in-ano
	* faecal impaction
	* endometriosis
	* diverticulitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 23 Jun 2019 07:26:19 +0000</pubDate>
        </item>
        <item>
            <title>dysmenorrhoea</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dysmenorrhoea</link>
            <description>dysmenorrhoea

see also:

	* gynaecology
	* chronic pelvic pain in women
	* premenstrual syndrome

introduction

	* dysmenorrhoea means painful menstruation and occurs in 3-90% of menstruating women depending on the population studied and criteria used to define it.
	* dysmenorrhoea may also refer to a symptom complex (perhaps better referred to as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 02:14:51 +0000</pubDate>
        </item>
        <item>
            <title>dyspareunia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dyspareunia</link>
            <description>dyspareunia

see also:

	* gynaecology

introduction

	* dyspareunia refers to pain on sexual intercourse in the female.
	* it is classically divided into:
		* superficial - pain on the external genitalia or vaginismus due to reflex spasm of levator ani and perineal muscles which may be psychogenic.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Oct 2009 22:43:40 +0000</pubDate>
        </item>
        <item>
            <title>Dyspepsia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dyspepsia</link>
            <description>Dyspepsia

Summary

	* ~25% adults in Western society experience dyspeptic symptoms (epigastric pains/discomfort) at least monthly whilst 5% experience daily symptoms
	* the main pathologic causes are:
		* peptic ulcer disease
		* gastro-oesophageal reflux with oesophagitis
		* non-ulcer dyspepsia (those that have no definite structural or biochemical explanation)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 30 Oct 2008 10:45:29 +0000</pubDate>
        </item>
        <item>
            <title>dysphagia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dysphagia</link>
            <description>dysphagia

see also:

	* gastroenterology

aetiology

painful dysphagia

	* gastro-oesophageal reflux
	* burns
	* pharyngitis
	* tonsillitis
	* herpangina
	* EBV / glandular fever / infectious mononucleosis
	* upper GIT foreign body - eg. fish bone
	* aortic dissection (Ortner's syndrome)
	* etc

non-painful dysphagia

	* upper GIT foreign body
	* stroke (CVA)
	* vertigo
	* oesophageal strictures
	* oesophageal cancer
	* stomach cancer
	* extrinsic masses
	* aortic dissection
	* achalasia
	* amy…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Mar 2026 23:09:57 +0000</pubDate>
        </item>
        <item>
            <title>dysuria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=dysuria</link>
            <description>dysuria

see also:

	* urinary tract infections (UTIs) / cystitis
	* sexually transmitted infections (STDs/STIs)
	* vulvovaginitis
	* painful bladder syndromes:
		*  interstitial cystitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 23 Jun 2019 07:27:55 +0000</pubDate>
        </item>
        <item>
            <title>evidence based medicine (EBM)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ebm</link>
            <description>evidence based medicine (EBM)

see also:

	* therapeutics - risks and benefits of therapies, medications, drugs, etc
	* research and innovation in emergency medicine
	* journal club
	* journal links
	* Medical statistical analysis
	* medical web portals, directories, news aggregators, etc
	* NNT.com's EBM analyses

levels of evidence

	* Level I: Evidence obtained from at least one properly designed randomized controlled trial.
	* Level II-1: Evidence obtained from well-designed controlled trial…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 13 Apr 2014 05:44:40 +0000</pubDate>
        </item>
        <item>
            <title>Ebola virus disease (EVD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ebola</link>
            <description>Ebola virus disease (EVD)

see also:

	* viruses
	* WH Ebola plan Dec 2014
	* WHO - Ebola
	* Aust. Govt. - Ebola information
	* Aust. Govt. case definitions Ebola
	* Vic. Govt Ebola Response Plan 2014 (pdf)
		* if suspect a case (see below for criteria):
			* under law must notify the Department (DH) immediately by calling 1300 651 160 in order to enable an assessment by the Chief Health Officer (CHO) or delegate and in order to trigger other immediate public health actions.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 12 Dec 2014 06:02:46 +0000</pubDate>
        </item>
        <item>
            <title>EBV / glandular fever / infectious mononucleosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ebv</link>
            <description>EBV / glandular fever / infectious mononucleosis

see also:

	* viruses
	* tonsillitis
	* NSW: patient information sheet (pdf)

introduction

	* Epstein-Barr Virus (EBV) is the virus that causes glandular fever (infectious mononucleosis or IM)
	* a frequent infection, particularly in young adults, mainly due to spread via saliva such as kissing or sharing drinks</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Apr 2016 06:10:11 +0000</pubDate>
        </item>
        <item>
            <title>ECG diagnosis of AMI</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_ami</link>
            <description>ECG diagnosis of AMI

see also:

	* The basics of reading an ECG
	* patterns of ECGs
	* an approach to the ECG with ST elevation
	* acute myocardial infarction (AMI/STEMI/NSTEMI)
	* William Brady's presentation on High Risk ED ECG Presentations at ICEM 2012 (pdf)

introduction

	* ~45% of all AMI's on presentation to ED develop diagnostic ST elevation AMI, while the remainder are categorised as NSTEMI.
	* this is further compounded by the fact that most ST elevations on an ECG are not caused by …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 06 Jul 2017 23:39:54 +0000</pubDate>
        </item>
        <item>
            <title>benign early repolarisation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_ber</link>
            <description>benign early repolarisation

see also:

	* The basics of reading an ECG
	* patterns of ECGs
	* LITFL - an excellent tutorial on BER
	* EMRAP TV Episode 36: Benign early repolarization

introduction

	* BER is thought to be a normal variant
	* occurs in 1% of population and at all ages and races but in some 13% of patients presenting to ED with chest pain!
	* mainly in those under 50 yrs of age and rarely in those aged &gt; 70yrs</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 11 Jun 2024 23:59:01 +0000</pubDate>
        </item>
        <item>
            <title>Brugada syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_brugada_synd</link>
            <description>Brugada syndrome

see also:

	* ECG diagnosis of AMI
	* wikipedia
	* Life in the fast lane's web page and ECG on Brugada syndrome

Introduction

	* 1st described in 1986 by Brugada in Barcelona, but 1st abstract of 4 patients in 1992 and 1st paper of 8 patients in 1992 by Pedro and Josep Brugada
		* SCN5A gene mutation identified in 1998 and since then over 200 mutations of this gene have been identified but loss of function of sodium channel only identified in 18-30% of cases</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 28 Jun 2025 08:07:44 +0000</pubDate>
        </item>
        <item>
            <title>de Winter syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_dewinter</link>
            <description>de Winter syndrome

see also:

	* the adult patient with chest pain in the ED
	* acute myocardial infarction (AMI/STEMI/NSTEMI)

Introduction

	* de Winter syndrome is an uncommon ECG pattern in patients with acute ischaemic chest pain which is found in 2% of acute LAD occlusions and is an indication for urgent coronary angiography in the same way that a</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 07 Sep 2023 08:12:31 +0000</pubDate>
        </item>
        <item>
            <title>The basics of reading an ECG</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_easy</link>
            <description>The basics of reading an ECG

see also in this wiki:

	* cardiology
	* cardiac arrhythmias
	* cardiac conduction blocks
	* Pattern recognition of ECGs
	* an approach to the ECG with ST elevation
	* ECG Diagnosis of AMI
	* ECG Stampede exercises
	* Peter Kaz's Own The ECG website

see also:

	*  ECG Library.com - a nice library of ECG images with interpretations
	*  anaesthetist.com - primer on ECGs
	* Utah med school's ECG learning centre
	* 12lead ECG.com - practice ECGs
	* LITFL's top 100 ECGs…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 02 Aug 2025 11:44:13 +0000</pubDate>
        </item>
        <item>
            <title>Fascicular heart blocks</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_fascb</link>
            <description>Fascicular heart blocks

see also see also cardiology, basics of the ECG, ECG Diagnosis of AMI

Unifascicular blocks

	* a conduction block that affects one of the three major infranodal conduction pathways:
		* right bundle branch - see RBBB
		* left anterior superior fascicle (LASF) eg. left anterior hemiblock (LAHB)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 11 Sep 2008 05:28:00 +0000</pubDate>
        </item>
        <item>
            <title>ECG - flat T waves</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_flatt</link>
            <description>ECG - flat T waves

see also:

	* cardiology
	* basics of the ECG
		*  ECG - tall T waves
		*  ECG - biphasic or inverted T waves
		* an approach to the ECG with ST elevation
		* ECG Diagnosis of AMI

	* the adult patient with chest pain in the ED

Introduction

	* if generalised, may be due to:
		*  hypokalaemia esp. if U waves present
		*  very large chest wall (generalised low voltages)
		*  hypothyroidism (generalised low voltages)
		*  restrictive cardiomyopathy (generalised low voltages)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Sep 2024 13:07:12 +0000</pubDate>
        </item>
        <item>
            <title>ECG - biphasic or inverted T waves</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_invertedt</link>
            <description>ECG - biphasic or inverted T waves

see also:

	* cardiology
	* basics of the ECG
		*  ECG - tall T waves
		*  ECG - flat T waves
		* an approach to the ECG with ST elevation
		* ECG Diagnosis of AMI

	* the adult patient with chest pain in the ED

Introduction

	* pathologically inverted T waves on an ECG can be very important indicators of significant disease processes

Biphasic T waves

	* may represent life threatening</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Sep 2024 13:53:22 +0000</pubDate>
        </item>
        <item>
            <title>left axis deviation (LAD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_lad</link>
            <description>left axis deviation (LAD)

see also:

	* The basics of reading an ECG
	* right axis deviation (RAD)

introduction

	* left axis deviation is an ECG finding where the mean frontal QRS axis is between -30 deg to - 90deg
	* the normal QRS axis is -30deg to +90deg

aetiology

	* left ventricular hypertrophy (LVH)
		* LAD is suggestive of LVH when other features of LVH are present, but is an insensitive indicator of LVH</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Sep 2009 00:54:53 +0000</pubDate>
        </item>
        <item>
            <title>Left Bundle Branch Block (LBBB)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_lbbb</link>
            <description>Left Bundle Branch Block (LBBB)

see also:

	* cardiology
	* basics of the ECG
	* ECG Diagnosis of AMI
	* Fascicular blocks
	* EMRAP TV Episode 29: LBBB in ACS

LBBB:

	* ECG:
			* QRS duration &gt; 0.11sec
			* M shape in leads I, V5 or V6
			* QS complex usually present in leads facing RV ie. V1
				* but &lt;50% have small r wave in V1

			* ST elevation common in V1-4 with ST-T waves opposite in direction to terminal QRS direction</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Sep 2009 22:50:01 +0000</pubDate>
        </item>
        <item>
            <title>left ventricular hypertrophy (LVH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_lvh</link>
            <description>left ventricular hypertrophy (LVH)

see also:

	* cardiology
	* patterns of ECGs

introduction

	* LVH results from chronic left-sided pressure or volume overload

aetiology

	* pressure “systolic” overload resulting in concentric LV wall thickening:
		* systemic arterial</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Mar 2019 08:49:26 +0000</pubDate>
        </item>
        <item>
            <title>patterns of ECGs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_patterns</link>
            <description>patterns of ECGs

see also:

	* cardiology
	* cardiac arrhythmias
	* LITFL ECG library - a must to check out!
		*  LITFL killer ECG patterns part 1 - non-ischaemic
		*  LITFL killer ECG patterns part 2 - ischaemic

	* basics of the ECG
		*  ECG - tall T waves
		*  ECG - flat T waves
		*  ECG - biphasic or inverted T waves

	* an approach to the ECG with ST elevation
	* ECG Diagnosis of AMI
	* the adult patient with chest pain in the ED

Obvious arrhythmias:

	*  Ventricular fibrillation (VF)
	* …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Sep 2024 03:25:58 +0000</pubDate>
        </item>
        <item>
            <title>right axis deviation (RAD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_rad</link>
            <description>right axis deviation (RAD)

see also:

	* The basics of reading an ECG
	* left axis deviation (LAD)

introduction

	* right axis deviation is an ECG finding where the mean frontal QRS axis is between +90 deg to +180deg
	* the normal QRS axis is -30deg to +90deg

aetiology

	* normal in children
		* may persistent into early adulthood, particularly if patient is tall and thin</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Sep 2009 01:12:18 +0000</pubDate>
        </item>
        <item>
            <title>Right Bundle Branch Block (RBBB)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_rbbb</link>
            <description>Right Bundle Branch Block (RBBB)

see also:

	* cardiology
	* basics of the ECG
	* ECG Diagnosis of AMI
	* Fascicular blocks
	* EMRAP TV Episode 23: Right Bundle Branch Block

Introduction

	* due to its endocardial course, the right bundle branch in the heart is relatively fragile and is easily impaired resulting in either an incomplete or a complete RBBB on the ECG</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Nov 2024 10:19:34 +0000</pubDate>
        </item>
        <item>
            <title>right ventricular hypertrophy (RVH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_rvh</link>
            <description>right ventricular hypertrophy (RVH)

see also:

	* cardiology
	* patterns of ECGs
	* right axis deviation (RAD)

introduction

	* RVH often results from chronic right-sided pressure overload

aetiology

	* congenital heart disease (CHD) causing RV outflow tract obstruction such as:
		* pulmonary atresia
		* pulmonic stenosis
		* Fallot's tetralogy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Sep 2009 03:37:50 +0000</pubDate>
        </item>
        <item>
            <title>an approach to the ECG with ST elevation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_ste</link>
            <description>an approach to the ECG with ST elevation

see also:

	* The basics of reading an ECG
	* patterns of ECGs
	* ECG diagnosis of AMI
	* EMRAP TV Episode 53: 11 causes of ST Elevation

introduction

	* a common dilemma on a daily basis in adult ED's is the patient with an ECG with ST elevation - does this patient warrant urgent angioplasty or thrombolysis, or is it non-ischaemic in nature?</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Aug 2014 11:20:05 +0000</pubDate>
        </item>
        <item>
            <title>ECG - tall T waves</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_tallt</link>
            <description>ECG - tall T waves

see also:

	* cardiology
	* basics of the ECG
		*  ECG - flat T waves
		* an approach to the ECG with ST elevation
		* ECG Diagnosis of AMI

	* the adult patient with chest pain in the ED

Introduction

	* tall T waves on the ECG may represent a life threatening condition - see aetiology below

Aetiology

life threatening

	* hyperkalaemia - usually tall narrow symmetric peaked T waves
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Sep 2024 13:07:27 +0000</pubDate>
        </item>
        <item>
            <title>Wellen's syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecg_wellens_synd</link>
            <description>Wellen's syndrome

see also:

	* an approach to the ECG with ST elevation
	* ECG diagnosis of AMI

introduction

	* deep, prominent T wave inversion or biphasic T waves in leads V2-4 in the presence of persistent R waves
	* probably represents transient STEMI due to occlusion of the LAD that, before the ECG, spontaneously opened or received collateral flow.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 May 2020 04:02:47 +0000</pubDate>
        </item>
        <item>
            <title>echinococcosis (hydatids)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=echinococcosis</link>
            <description>echinococcosis (hydatids)

see also:

	* parasites
	* zoonoses
	* wikipedia

introduction

	* often referred to as hydatid disease or echinococcal disease
	* a tapeworm parasitic disease that affects both humans and other mammals, such as sheep, dogs, rodents and horses

echinococcus life cycle</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 05 Jan 2012 06:46:48 +0000</pubDate>
        </item>
        <item>
            <title>eclampsia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=eclampsia</link>
            <description>eclampsia

see also seizures, Obstetrics, magnesium, pre-eclampsia and eclampsia

Mx of eclampsia in the ED

	* Airways, Breathing
		* if GCS still low, have a low threshold for intubation as likely to require emergent LUSCS

	* Circulation
		* iv access
		* left lateral position for optimised fetal circulation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 31 May 2023 13:24:12 +0000</pubDate>
        </item>
        <item>
            <title>E. coli</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ecoli</link>
            <description>E. coli

see also:

	* enterobacteriaceae
	* carbapenemase producing or resistant enterobacteriaceae (CPE/CRE)

Introduction

	* E.coli are extremely common bowel flora bacteria and commonly are a cause of urinary tract infections (UTIs) / cystitis and urosepsis
		*  a US 2025 study   suggests that ~20% of UTIs are caused by extraintestinal pathogenic E.coli strains (ExPEC) spread from contaminated meats, especially poultry</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Nov 2025 11:18:06 +0000</pubDate>
        </item>
        <item>
            <title>ectopic pregnancy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ectopic_pregnancy</link>
            <description>ectopic pregnancy

see also:

	* gynaecology
	* 
EMRAPTV Episode 49: Ectopic Pregnancy June 2008 lecture
	* RCOG guidelines Mx of ectopic (pdf)

introduction

	* ectopic pregnancy is said to occur in ~2% of all pregnancies with a rising incidence
	* it accounts for 9% of all pregnancy related deaths in the USA
	* although the diagnosis of ectopic pregnancy has become more reliable and at earlier gestation with improving ultrasound technology, diagnosis is still often delayed or missed, usually b…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 Jan 2019 05:48:11 +0000</pubDate>
        </item>
        <item>
            <title>atopic eczema</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=eczema</link>
            <description>atopic eczema

see also:

	* RCH guideline - eczema
	* scalp and hair conditions
	* dermatology

Introduction

	* a chronic inflammatory dermatitis that affects 30% of children, often starting under the age of 12 months, and some may continue to have it lifelong
	* it appears that a key enzyme, Granzyme B, is secreted by cells and weakens the skin barrier by cleaving through the proteins holding cells together making it easier for allergens to penetrate across, and that by knocking out Granzyme …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Feb 2026 10:12:04 +0000</pubDate>
        </item>
        <item>
            <title>editors and authors of this wiki</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=editors</link>
            <description>editors and authors of this wiki

see also:

	* about the OzEMedicine wiki
	* welcome to the OzEMedicine Wiki
	* information for wiki authors here, such as syntax, etc. - only authorised users are permitted to update or create Wiki pages.

editor-in-chief

	* Dr Gary Ayton, MBBS, FACEM, OAM
	* past Director Emergency Department, Western Health
	* more than 35 years experience working in emergency departments, and over 15 years experience with computer programming.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 07 Dec 2025 11:29:24 +0000</pubDate>
        </item>
        <item>
            <title>common emergency department patient presentations</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=edpresentations</link>
            <description>common emergency department patient presentations

Metropolitan emergency department adult presentations

top ED triage symptom codes

	* abdominal pain = 4.7%
	* other = 4.1%
	* chest pain = 4%
	* shortness of breath = 3.5%
	* laceration = 3.2%
	* generally unwell = 2.7%</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 31 Aug 2009 04:05:32 +0000</pubDate>
        </item>
        <item>
            <title>Working in Emergency Medicine in Australia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ed_in_australia</link>
            <description>Working in Emergency Medicine in Australia

	* professional bodies including medical registration boards and ACEM

Overseas trained doctors wanting to work in Australia

	* there are many opportunities to work in ED's in Australia as long as you fit the basic criteria for obtaining a working visa in medicine.
	* essentially if you are a graduate from the UK, Ireland USA, Canada or NZ, you may satisfy the</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 27 Oct 2020 02:21:27 +0000</pubDate>
        </item>
        <item>
            <title>ED life hacks</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ed_life_hacks</link>
            <description>ED life hacks

see also:

	* Western Health ED main page
	* Sunshine ED Fast Track

Introduction

This is a quick reference guide to services in ED and how to make your shift run smoother. Topics are listed on the right side as a navigation aid. If you think of anything else you would like to add contact Gary.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 21 Sep 2024 05:54:09 +0000</pubDate>
        </item>
        <item>
            <title>Ehlers-Danlos syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ehlersdanlos</link>
            <description>Ehlers-Danlos syndrome

see also:

	* connective tissue (CT) disorders
	* collagen disorders
	* Marfan's syndrome
	* joint hypermobility disorders and syndromes
	* see Ehlers Danlos Foundation - diagnostic types, tests and features

introduction

	* rare genetic collagen disorder usually AD (except kyphoscoliosis and dermatosparaxis, and other less common types) affecting some 1 in 400,000 people
	* several sub types

clinical features</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Mar 2023 20:40:49 +0000</pubDate>
        </item>
        <item>
            <title>eicosanoids including prostaglandins</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=eicosanoids</link>
            <description>eicosanoids including prostaglandins

see also autacoids, platelet activating factor, physiology main index, pharmacology main index

Introduction:

	* Eicosanoids are autacoids derived from membrane phospholipids - mainly formed from polyunsaturated fatty acids (principally arachidonic acid) - 20 carbon essential fatty acids that contain 3-5 double bonds - hence eicosanoids &amp; include</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Sep 2013 08:37:19 +0000</pubDate>
        </item>
        <item>
            <title>elastin disorders</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=elastin</link>
            <description>elastin disorders

see also:

	* connective tissue (CT) disorders
	* collagen disorders
	* Williams-Beuren syndrome (WBS)
	* hallux valgus (bunions)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 02 Feb 2013 13:32:13 +0000</pubDate>
        </item>
        <item>
            <title>the acutely painful elbow</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=elbowpain</link>
            <description>the acutely painful elbow

see also:

	* the painful shoulder

introduction

	* elbow pain is a very common presentation to the ED
	* one needs to differentiate local injury or inflammation to that from referred pain

referred pain

	* a painful stimulus involving the diaphragm or the mediastinum commonly results in referred shoulder tip pain, usually on the same side, but can occasionally also cause pain referred distally down the arm.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Jan 2025 09:43:31 +0000</pubDate>
        </item>
        <item>
            <title>dislocation of the elbow joint</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=elbow_dislocation</link>
            <description>dislocation of the elbow joint

see also:

	* the acutely painful elbow

Introduction

	* the elbow is the second most commonly dislocated large joint after the shoulder joint
	* 80% are postero-lateral
	* most have osteochondral injury which may only be evident on surgical exploration but fortunately, most do not require intervention</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Jan 2025 12:42:32 +0000</pubDate>
        </item>
        <item>
            <title>pulled elbow</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=elbow_pulled</link>
            <description>pulled elbow

see also:

	* orthopaedics in the ED
	* RCH patient information sheet - pulled elbow (pdf)

introduction

	* pulled elbow is a very common cause of a child (usually under age 6 years) refusing to move their arm.
	* it is a subluxation of the immature radial head and is not detectable radiologically and thus is a clinical diagnosis.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 Dec 2021 06:52:50 +0000</pubDate>
        </item>
        <item>
            <title>electrocution / electrical injury</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=electrocution</link>
            <description>electrocution / electrical injury

see also:

	* burns

Introduction

	* the electrical flux energy is carried in the electromagnetic fields surrounding wires and other components of an electric circuit
	* most injuries occur due to becoming part of the electrical circuit by contact</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 07 Sep 2025 07:16:24 +0000</pubDate>
        </item>
        <item>
            <title>elephantiasis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=elephantiasis</link>
            <description>elephantiasis

see also:

	* parasites
	* travel medicine
	* wikipedia

introduction

	* elephantiasis is a disease that is characterized by the thickening of the skin and underlying tissues, especially in the legs and male genitals
	* it is caused by either:
		* filariasis in tropical regions and Africa - especially Kenya where 6% of the population are affected in endemic areas</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 05 Jan 2012 04:36:38 +0000</pubDate>
        </item>
        <item>
            <title>elevated hemidiaphragm</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=elevated_hemidiaphragm</link>
            <description>elevated hemidiaphragm

see also:

	* the chest X-ray (CXR)

Introduction

	* the diaphragm normally flattens during inspiration
	* the diaphragm is the primary muscle for inspiration since it accounts for 80% of the power required for respiration.
	* an elevated hemidiaphragm is usually an incidental finding on an inspired CXR and generally not symptomatic due to the compensation and recruitment of other inspiratory muscles and the other hemidiaphragm</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Nov 2020 01:12:50 +0000</pubDate>
        </item>
        <item>
            <title>electromagnetic field (EMF) health hazards</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=emf</link>
            <description>electromagnetic field (EMF) health hazards

see also:

	* Ionising radiation
	* &lt;https://www.theiet.org/media/9587/electromagnetic-fields-and-health.pdf&gt;
	* &lt;https://www.arpansa.gov.au/sites/default/files/legacy/pubs/rps/rps3_hocking.pdf&gt;

Introduction

	* electromagnetic waves such as radio waves and light waves have an electrical wave and a magnetic wave at right angles to it and thus sources can give off both an electric field and a magnetic field</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Aug 2025 07:49:49 +0000</pubDate>
        </item>
        <item>
            <title>empty sella syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=empty_sella_syndrome</link>
            <description>empty sella syndrome

see also:

	* neurology

introduction

	* empty sella is usually an incidental finding seen in some patients on CT brain scan
	* it implies that the pituitary is either shrunken or displaced from the sella turcica by subarachnoid fluid due to raised intracranial pressure with herniation of the arachnoid space into pituitary fossa through a deficient diaphragm, found in 20% of the population</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 31 May 2025 23:31:10 +0000</pubDate>
        </item>
        <item>
            <title>EM in the UK</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=em_uk</link>
            <description>EM in the UK

see also:

	* NHS junior doctors award rates agreement with BMA 2016
		* no longer weekend penalties but a percent increase in salary depending upon how many weekends work pa to a maximum salary increase of 10% if &gt; 7 full weekends worked pa
		* night shift penalty reduced from 50% to 37%</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 May 2016 23:32:12 +0000</pubDate>
        </item>
        <item>
            <title>ENA (extractable nuclear antigen)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ena</link>
            <description>ENA (extractable nuclear antigen)

see also:

	* pathology

introduction

	* ENA is a blood test looking for extractable nuclear antigens which are &gt;100 different soluble cytoplasmic and nuclear antigens. 
	* autoantibodies to these antigens are associated with particular</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Dec 2015 03:57:14 +0000</pubDate>
        </item>
        <item>
            <title>encephalitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=encephalitis</link>
            <description>encephalitis

see also:

	* meningitis
	* encephalopathy
	* Herpes simplex virus (HSV)

introduction

	* inflammation of the brain parenchyma which may or may not be associated with meningitis
	* the most common cause in in immunocompetent adults in Western society is caused by herpes simplex virus, while varicella may be life threatening in immunocompromised patients and thus patients with suspected encephalitis should generally by started on high dose iv antivirals</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jan 2026 12:53:04 +0000</pubDate>
        </item>
        <item>
            <title>encephalopathy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=encephalopathy</link>
            <description>encephalopathy

see also:

	* encephalitis
	* neurology
	* progressive multifocal leukoencephalopathy (PML)
	* multiple sclerosis (MS)

introduction

	* a broad term which is variably used but essentially is used when there is acute or subacute global organic dysfunction of cerebral function which may or may not be reversible
	* this usually results in inability to concentrate, personality changes, lethargy, loss of cognitive function,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Aug 2018 12:50:30 +0000</pubDate>
        </item>
        <item>
            <title>infective endocarditis (including SBE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=endocarditis</link>
            <description>infective endocarditis (including SBE)

see also:

	* The febrile adult presenting to the ED
	* wikipedia

introduction

	* non-infective endocarditis or marantic endocarditis is due to thromboses on previously normal heart valves and occurs in hypercoagulable states including pregnancy and may cause emboli but not the septic or inflammatory characteristics of infective endocarditis which is the topic of this article.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 13 Jun 2023 02:50:25 +0000</pubDate>
        </item>
        <item>
            <title>endocrinology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=endocrinology</link>
            <description>endocrinology

	* diabetes insipidus
	* diabetes mellitus
	* diabetic ketoacidosis
	* diabetes mellitus in children
	* thyroid physiology and hormones
	* hyperthyroidism
	* hypothyroidism
	* endocrine disrupting chemicals (EDCs)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 29 Dec 2023 23:06:08 +0000</pubDate>
        </item>
        <item>
            <title>end of life care</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=endoflife</link>
            <description>end of life care

see also:

	* ethical issues in emergency medicine
	* NSW College of Emergency Nursing - End of Life guidelines (pdf)
	* NSW Govt - End of Life Care and decision making guidelines
	* death and the potentially dead
	* Safer Care Victoria - Checklist for care plan for preparing patient to die at home
	* Victorian Advanced Care Directives forms
	* A Good Death - a NZ film about end of life care and advance care planning
	* The Age 2014: Looking for a way to go
	* louisvillelecture…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 08 Sep 2023 07:56:53 +0000</pubDate>
        </item>
        <item>
            <title>endolymphatic hydrops including Meniere's disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=endolymphatic_hydrops</link>
            <description>endolymphatic hydrops including Meniere's disease

see also:

	* ED Mx of vertigo and BPV
	* tinnitus
	* deafness / hearing loss

introduction

	* refers to conditions associated with excess fluid build up in the endolymphatic spaces of the inner ear
	* this typically causes vertigo, tinnitus, fullness in the ear(s) and possibly sensorineural deafness</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 27 Sep 2013 08:40:16 +0000</pubDate>
        </item>
        <item>
            <title>endometriosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=endometriosis</link>
            <description>endometriosis

see also

	* gynaecology
	* RIF or pelvic pain
	* LIF or pelvic pain
	* dysmenorrhoea
	* chronic pelvic pain in women
	* Endometriosis Care Centre Of Australia
	* Epworth Julia Argyrou endometriosis centre

introduction

	* endometriosis is defined as the presence of endometrial glandular and stromal tissue outside the uterine cavity.
	* it is dependent upon oestrogen
	* clinical flare ups tend to have a catamenial (cyclical) pattern, occurring between 24h before and 72h after the…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 22 Feb 2026 12:43:27 +0000</pubDate>
        </item>
        <item>
            <title>endocrine disrupting chemicals (EDCs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=endo_chemicals</link>
            <description>endocrine disrupting chemicals (EDCs)

see also:

	* endocrinology
	* foods that may be toxic or bad for you
	* &lt;https://www.who.int/teams/environment-climate-change-and-health/settings-and-populations/children/endocrine-disrupters&gt;
	* WHO publication 2002 Global assessment on the state of the science of endocrine disruptors

Introduction

	* endocrine disrupting chemicals (EDCs) are chemicals which can mimic, block, or interfere with the body's hormones
	* 95% of people have endocrine disruptin…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Apr 2026 00:46:46 +0000</pubDate>
        </item>
        <item>
            <title>enoxaparin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=enoxaparin</link>
            <description>enoxaparin

see also:

	* anticoagulants

introduction

	* enoxaparin (Clexane) is a low molecular weight (LMW) heparin which is usually given bd or daily s/c in the prevention or Rx of deep venous thrombosis (DVT) or pulmonary embolism (PE) or in Mx of acute coronary syndromes, but can also be given as an initial iv bolus.
	* It has several actions on the coagulation pathway through binding to antithrombin III. The antithrombotic activity is related to inhibition of thrombin generation and inhi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 04 Jun 2021 22:56:44 +0000</pubDate>
        </item>
        <item>
            <title>ears, nose and throat surgery (ENT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ent</link>
            <description>ears, nose and throat surgery (ENT)

	* paediatric emergency medicine
	* otitis media
	* otitis externa
	* deafness / hearing loss
		* drug induced ototoxicity

	* ED Mx of vertigo and BPV
	* epistaxis
	* sinusitis
	* odontogenic sinusitis
	* nasopharyngeal carcinoma
	* the child with a sore throat
	* sore throats in adults
		* Ludwig's angina - floor of mouth infection
		* Lemiere's syndrome
		* Vincent's angina - fusospirochaetal infection of the pharynx and tonsils
		* Vincent's gingivitis - …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Feb 2025 00:30:26 +0000</pubDate>
        </item>
        <item>
            <title>enterobacteriaceae</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=enterobacteriaceae</link>
            <description>enterobacteriaceae

see also:

	* clinically important bacteria
	* carbapenemase producing or resistant enterobacteriaceae (CPE/CRE)

introduction

	* fermentative, non-fastidious, oxidase negative, facultative anaerobic, Gram -ve rods

genera

	* Escherichia (acid f.lactose)
					*  E. coli

				* Edwardsiella
				* Citrobacter (acid f.lactose)
				*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 11 Jul 2024 05:54:46 +0000</pubDate>
        </item>
        <item>
            <title>Enterococci</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=enterococcus</link>
            <description>Enterococci

see also:

	* clinically important bacteria
	* Lactobacillales
	* streptococcus / streptococcal infections

Introduction

	* enterococci belong to the Enterococcaceae family which belongs to the Lactobacillales
	* it is a large genus of lactic acid Gram positive cocci bacteria that often occur as diplococci or in short chains and can be difficult to distinguish from</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 03:33:02 +0000</pubDate>
        </item>
        <item>
            <title>enteropathy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=enteropathy</link>
            <description>enteropathy

see also:

	* diarrhoea

Introduction

	* a non-specific term that covers diseases of the intestine

Aetiology

	* protein losing enteropathy
	* eosinophilic enteropathy
	* coeliac disease
	* HIV / AIDS enteropathy
	* lymphoma enteropathy
	* radiation enteropathy 
	* tropical enteropathy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Aug 2018 11:36:19 +0000</pubDate>
        </item>
        <item>
            <title>Envenomation and bites</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=envenomation</link>
            <description>Envenomation and bites

see:

	* toxinology
	* Australian tiger and brown snake bites</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 Oct 2009 02:59:37 +0000</pubDate>
        </item>
        <item>
            <title>eosinophilic oesophagitis (EoE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=eoe</link>
            <description>eosinophilic oesophagitis (EoE)

see also:

	* Dyspepsia
	* oesophagitis in adults
	* gastro-oesophageal reflux
	* oesophageal cancer
	* gastroenterology
	* the adult patient with chest pain in the ED

Introduction

	* EoE is perhaps the second most common oesophageal condition after gastro-oesophageal reflux
	* it is a non-IgE-mediated condition caused by various food allergies resulting in chronic oesophagitis and histologic changes dominated with eosinophils</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 27 May 2024 23:57:54 +0000</pubDate>
        </item>
        <item>
            <title>eosinopenia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=eosinopenia</link>
            <description>eosinopenia

see also:

	* full blood examination (FBE)
	* neutropenia
	* eosinophilia
	* basophilopenia

introduction

	* eosinopenia is usually an incidental finding of little significance to the ED physician

aetiology

	* acute bacterial infection
	* corticosteroids
	* hypogammaglobulinaemia
	* physical stress
	* thymoma</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Aug 2013 14:25:32 +0000</pubDate>
        </item>
        <item>
            <title>eosinophilia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=eosinophilia</link>
            <description>eosinophilia

see also:

	* allergy and hypersensitivity reactions
	* urticaria
	* eosinophilic meningitis - eosinophils predominate the CSF
	* full blood examination (FBE)

DDx of eosinophilia on peripheral blood film

	* allergy and hypersensitivity reactions
	* drug reactions:
		* asymptomatic eosinophilia:
			* olanzapine

		* drug reactions with eosinophilia and systemic symptoms (DRESS):
			* aromatic anticonvulsants and other antiepileptics,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 09 Jul 2025 07:01:51 +0000</pubDate>
        </item>
        <item>
            <title>eosinophilic enteropathy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=eosinophilic_enteropathy</link>
            <description>eosinophilic enteropathy

see also:

	* diarrhoea
	* enteropathy

Introduction

	* an enteropathy characterised by raised levels of eosinophils in the gut and / or blood
	* can affect any part of the gastrointestinal tract, and is often named by the part affected: colon (colitis), esophagus (oesophagitis), stomach (gastritis), or both the stomach and small intestine (eosinophilic gastroenteritis)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Aug 2019 15:14:46 +0000</pubDate>
        </item>
        <item>
            <title>epidemiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=epidemiology</link>
            <description>epidemiology

see also:

	* pandemics - influenza, coronavirus, Ebola
	* pandemic epidemiology
	* population-attributable fraction (PAF)
	* risk factor and treatment benefit metrics</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Apr 2020 02:00:49 +0000</pubDate>
        </item>
        <item>
            <title>epididymo-orchitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=epididymo-orchitis</link>
            <description>epididymo-orchitis

see also:

	* urology
	* acute scrotal pain or swelling
	* sexually transmitted infections (STDs/STIs)
	* torsion of testes

introduction

	* epididymo-orchitis is inflammation of the testes and usually falls into one of 4 main causes:
		* urinary tract infections (UTIs) / cystitis associated (usually in pre-pubertal boys, the elderly or following urethral instrumentation)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 26 Nov 2013 05:35:30 +0000</pubDate>
        </item>
        <item>
            <title>epidural abscess</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=epidural_abscess</link>
            <description>epidural abscess

see also:

	* acute spinal cord compression
	* Spinal cord syndromes and lesions

Introduction

	* spinal infections such as bacterial vertebral osteomyelitis / discitis or epidural abscess are not only neurologic emergencies for potential acute spinal cord compression, but are life threatening, particularly once infection spreads to the CSF
	* this should be considered in ANY patient with midline back pain and fever, especially if they have risk factors such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Mar 2020 04:43:04 +0000</pubDate>
        </item>
        <item>
            <title>epistaxis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=epistaxis</link>
            <description>epistaxis

see also:

	*  ears, nose and throat surgery (ENT)
	* LITFL - Dx and Mx of epistaxis
	* RCH paediatric guideline - epistaxis
	* Co-Phenylcaine Forte Spray
	* topical tranexamic acid in epistaxis

	* avoid inserting epistaxis control devices such as Rapid Rhino in patients with known telangectasiae such as Osler-Weber-Rendu disease, as these devices tend to cause further trauma on deflation and recurrence of bleeding</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 May 2017 09:58:12 +0000</pubDate>
        </item>
        <item>
            <title>ergometrine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ergometrine</link>
            <description>ergometrine

see also:

	* ED Mx of 3rd stage of labour
	* oxytocin

	* Oxytocin 10 units is the preferred uterotonic agent for active management of the third stage. It is preferred over other uterotonic drugs as it is effective straight away if administered IV, and within 2 to 4 minutes of administration if given IM.  It has minimal side effects and can be used in almost all women (except where there is a history of allergy to oxytocin or carbetocin).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 02:15:44 +0000</pubDate>
        </item>
        <item>
            <title>ergot alkaloids</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ergots</link>
            <description>ergot alkaloids

see also:

	* ergometrine
	* serotonin receptors and pharmacology
	* migraine

pharmacology:

	* non-selective 5HT agonists/antagonists - varies with agent - see also serotonin receptors and pharmacology
	* dopamine D2 agonists - see also dopamine
	* alpha adrenergic agonists - see also sympathomimetics
	* esp. on sm.muscle;
	* ergometrine is used as a uterotonic</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 01 Jun 2020 06:49:40 +0000</pubDate>
        </item>
        <item>
            <title>erythema multiforme</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=erythema_multiforme</link>
            <description>erythema multiforme

see also:

	* acute rashes in adults
	* paediatric exanthems
	* &lt;https://dermnetnz.org/topics/erythema-multiforme&gt;

Introduction

	* an uncommon non-contagious acute skin disorder possibly mediated by IgM complexes following infections (far majority are related to Herpes simplex virus (HSV)) or drug exposures.
	* peak incidence in the second and third decades of life</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 11 Jul 2022 09:26:11 +0000</pubDate>
        </item>
        <item>
            <title>erythema nodosum</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=erythema_nodosum</link>
            <description>erythema nodosum

introduction

	* painful red nodules usually over both shins (but may occur elsewhere) due to a hypersensitivity inflammatory reactions of the subcutaneous fat cells (panniculitis)
	* often associated with fever, malaise, and joint pain</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 31 Aug 2012 00:52:38 +0000</pubDate>
        </item>
        <item>
            <title>erythromelalgia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=erythromelalgia</link>
            <description>erythromelalgia

see also:

	* reflex sympathetic dystrophy (RSD) / complex regional pain syndrome / causalgia

Introduction

	* a chronic, life-long, rare condition which causes periodic erythema, hot, burning skin sensation, mainly of feet but may also affect hands, legs, arms or face.

Classification

primary erythromelalgia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 19 Jun 2025 07:27:54 +0000</pubDate>
        </item>
        <item>
            <title>esmolol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=esmolol</link>
            <description>esmolol

see also beta blockers

Summary:

	* Beta1 blocker with T1/2=10min due to rapid hydrolysis of an ester linkage by RBC esterases thus useful as antiarrhythmic &amp; in critically ill pt.
	* Peak IV effect 6-10min, rapid attenuation over 20min. after stop inf.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Feb 2009 10:06:29 +0000</pubDate>
        </item>
        <item>
            <title>erythrocyte sedimentation rate (ESR)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=esr</link>
            <description>erythrocyte sedimentation rate (ESR)

see also:

	* pathology
	* C reactive protein (CRP)

introduction

	* ESR is generally used as a marker of acute phase reaction and inflammation, although there are now better, more specific markers of acute phase reactions including:
		* C reactive protein (CRP)
		* serum amyloid A protein</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 26 Mar 2022 23:53:39 +0000</pubDate>
        </item>
        <item>
            <title>end stage renal failure (ESRF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=esrf</link>
            <description>end stage renal failure (ESRF)

see also:

	* acute kidney injury (AKI) / acute renal failure (ARF)
	* chronic renal failure</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Dec 2015 05:09:37 +0000</pubDate>
        </item>
        <item>
            <title>essential thrombocytosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=essential_thrombocytosis</link>
            <description>essential thrombocytosis

see also:

	* thrombocytosis
	* Janus kinase - STAT signalling

introduction

	* a myeloproliferative disorder characterised by a high platelet count of &gt; 600 × 10^3/µL for at least 2 months
	* incidence ~ 20 new cases per 1 million population per year
	* mainly effects middle aged and elderly</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 19 Jun 2025 07:32:22 +0000</pubDate>
        </item>
        <item>
            <title>ethanol (alcohol and alcohol withdrawal)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ethanol</link>
            <description>ethanol (alcohol and alcohol withdrawal)

see also:

	* ethanol intoxication
	* cirrhosis
	* Western Health policies (intranet only):
		* alcohol withdrawal
		* alcohol withdrawal scale


Introduction

	* ethanol is primarily a CNS depressant acting by stimulating GABAA receptor in the CNS.
	* from 1996-2005 throughout Australia, each year, an average of over 80,000 were hospitalised, and over 3,000 died from alcohol attributable injury and disease caused by risky/high risk drinking - mainly due…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Apr 2026 04:06:05 +0000</pubDate>
        </item>
        <item>
            <title>alcohol dependence</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ethanol_dependence</link>
            <description>alcohol dependence

see also:

	*  ethanol (alcohol and alcohol withdrawal); 
	*  alcoholism on Wikipedia;
	*  drug dependency;
	*  Addiction medicine - drug and alcohol
	*  refeeding syndrome
	* TWEAK alcoholism scoring tool

physical dependence:

	* “DT - level” requires:
		* blood concentration of ethanol &gt; 100mg/dl most of waking day (intake 200-350g/d) for period of 1wk, or,
		* 4-7wks at levels nearer 100mg/dl;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 May 2023 06:09:48 +0000</pubDate>
        </item>
        <item>
            <title>ethical issues in emergency medicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ethics</link>
            <description>ethical issues in emergency medicine

see also:

	* end of life care
	* NSW Govt - End of Life Care and decision making guidelines
	* Australian Medical Associan (AMA) Code of ethics
	* American Medical Association (AMA) - principles of medical ethics
	* NHMRC links to health ethics issues

general principles of ethics in medicine

autonomy

	* the right of the competent individual to determine what is or is not done to himself, and the right to choose one's own course</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 May 2012 08:01:41 +0000</pubDate>
        </item>
        <item>
            <title>Emergency medicine exam resources</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=exam_resources</link>
            <description>Emergency medicine exam resources

Australian exam resources

	* ACEM primary exam resources
	* ACEM fellowship exam resources
	* Global Medical Education Project

UK exam resources

	* mceexam.com - Emergency medicine MCQs for the MCEM part A
	* mcemrevision.com - Emergency medicine MCQs for the MCEM part A

USA resources</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 05 Apr 2013 09:40:43 +0000</pubDate>
        </item>
        <item>
            <title>paediatric exanthems</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=exanthems</link>
            <description>paediatric exanthems

see also:

	* viruses
	* urticaria
	* acute rashes in adults

introduction

	* “exanthems” are acute onset rashes with the term usually applied to children with fevers and macular or maculopapular rashes
	* the cause may be viral, bacterial, toxigenic or due to a drug sensitivity</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 24 Aug 2022 11:18:26 +0000</pubDate>
        </item>
        <item>
            <title>exercise for health</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=exercise</link>
            <description>exercise for health

see also:

	* nature exposure and benefits to health
	* atherosclerosis and primary prevention
	* obesity and weight management
	* frailty
	* Am Heart Association recommendations for exercise in adults

Introduction

	* regular exercise is critical to maintain cardiovascular health, reduce chronic disease risks including cancer and improve mental health
	* ideally there should be a variety of exercise types undertaken regularly such as walking, walking up hills or stairs, an…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Apr 2026 04:11:20 +0000</pubDate>
        </item>
        <item>
            <title>exposome and health</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=exposome</link>
            <description>exposome and health

see also:

	* foods that may be toxic or bad for you
	* risk and the perception of risk
	* air pollution and health risks
	* the GIT microbiome
	* genomics
	* metabolome
	* metabonomics
	* transcriptome
	* proteome

Introduction

	* the exposome is a measure of all the environmental or external exposures over our lifetime and the ways in which these impact our health
	* it includes diet, food and water toxins, lifestyle, education, income,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Aug 2025 00:41:57 +0000</pubDate>
        </item>
        <item>
            <title>extrapyramidal reactions such as oculogyric crisis, dystonic reactions, akathisia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=extrapyramidal_reactions</link>
            <description>extrapyramidal reactions such as oculogyric crisis, dystonic reactions, akathisia

see also:

	* parkinsonism

introduction

	* acute extrapyramidal reactions are quite common neurologic reactions in some patients who take medications which block dopamine D2 receptors</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 18 Dec 2017 03:52:35 +0000</pubDate>
        </item>
        <item>
            <title>extubation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=extubation</link>
            <description>extubation

see also:

	* rapid sequence induction (RSI) for emergency intubation
	* assisted ventilation
	* Mx of the newly intubated patient in ED - post-intubation
	* 2016: Update on post-extubation high-flow nasal cannula to reduce reintubation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 27 Mar 2016 22:15:32 +0000</pubDate>
        </item>
        <item>
            <title>chemical injuries and burns to the eyes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=eye_chemical</link>
            <description>chemical injuries and burns to the eyes

see also:

	* Eye injuries

Introduction

	* exposure of a chemical even in powder or dust form, may cause serious long term damage to the eye, particularly if they are alkali as they penetrate deeper into the ocular surface</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 Jul 2018 07:54:48 +0000</pubDate>
        </item>
        <item>
            <title>eye color phenotypes and disease associations</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=eye_color</link>
            <description>eye color phenotypes and disease associations

see also:

	* ophthalmology
	* genetics
	* color blindness / color vision deficiency

Introduction

	* phenotypic eye iris color is a genetic trait with those with blue eyes having a northern European genetic history (probably originated around the Baltic Sea region) while those of pure Asian or African ancestry, mostly have brown eyes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 13 Nov 2024 02:27:09 +0000</pubDate>
        </item>
        <item>
            <title>Eye injuries</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=eye_injuries</link>
            <description>Eye injuries

see also:

	*  ophthalmology
	*  chemical injuries and burns to the eyes
	*  welder flash burns - UV keratopathy (photo keratitis)
	*  corneal abrasions
	*  retrobulbar haemorrhage
	* RCH guideline - acute eye injuries in children
	* RCH guideline - penetrating eye injury
	* RCH guideline - the acute red eye

patient information sheets

	* Vic DHS - Eye injury - Flash burns (pdf)
	* Vic DHS - Eye injury - Foreign body (pdf)

introduction

	* patients with a possible open globe inju…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 10 Sep 2018 08:44:03 +0000</pubDate>
        </item>
        <item>
            <title>welder flash burns - UV keratopathy (photo keratitis)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=eye_uvkeratopathy</link>
            <description>welder flash burns - UV keratopathy (photo keratitis)

see also:

	*  ophthalmology
	*  chemical injuries and burns to the eyes
	*  ultraviolet light exposure (UV)
	* RCH guideline - the acute red eye

patient information sheets

	* Vic DHS - Eye injury - Flash burns (pdf)
	* Vic DHS - Eye injury - Foreign body (pdf)

Introduction

	* exposure to UV radiation (wavelengths 295-400nm) can result in delayed onset painful eyes due to UV keratopathy

Clinical features

	* bilateral severe eye pain wi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 23 May 2024 06:52:48 +0000</pubDate>
        </item>
        <item>
            <title>Ezh2 antagonists</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ezh2antagonists</link>
            <description>Ezh2 antagonists

see also:

	* neoplasia / cancer / tumours
	* scleroderma
	* asthma
	* wikipedia: EZH2

Introduction

	* Ezh = Enhancer of zeste homolog
	* Ezh2 is the is the catalytic subunit of the Polycomb Repressive Complex 2 (PRC2) and a member of the SET domain family of lysine methyltransferases which function to add methyl groups to lysine side chains of substrate proteins.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 17 May 2019 09:39:36 +0000</pubDate>
        </item>
        <item>
            <title>facial pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=facial_pain</link>
            <description>facial pain

see also:

	* ophthalmology
	* faciomaxillary

Introduction

	* most non-traumatic causes of facial pain have a clear tender focus or skin abnormality which may point to conditions such as:
		*  sinusitis
		*  odontogenic sinusitis
		*  Periorbital and orbital cellulitis
		*  cellulitis
		*  skin abscess
		*  dental abscess
		*  acute dental pain / dental abscess
		*  eye conditions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2024 06:38:52 +0000</pubDate>
        </item>
        <item>
            <title>facial weakness</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=facial_palsy</link>
            <description>facial weakness

see also:

	* RCH guideline - facial weakness and Bell's palsy
	* facial nerve palsy / Bell's palsy
	* stroke (CVA)

could it be an acute stroke?

features that suggest stroke rather than facial nerve palsy

	* any one or more of:
		* new weakness of arm or leg
		* new dysphasia
		* sparing of the forehead muscles (eg. forehead folds persist)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 24 May 2017 05:34:10 +0000</pubDate>
        </item>
        <item>
            <title>non-traumatic facial swelling / oedema</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=facial_swelling</link>
            <description>non-traumatic facial swelling / oedema

see also:

	* facial rashes
	* facial trauma

Introduction

	* non-traumatic facial swelling is a relatively common presentation to the ED

Aetiology

	* angioedema
	* anaphylaxis
	* urticaria
	* insect bites
	* dental abscess
	* facial cellulitis / superficial abscess</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 17 May 2017 15:37:12 +0000</pubDate>
        </item>
        <item>
            <title>faciomaxillary</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=faciomaxillary</link>
            <description>faciomaxillary

see also:

	* temporomandibibular joint disorders
	* facial trauma
	* dental</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 04 Jun 2015 07:22:04 +0000</pubDate>
        </item>
        <item>
            <title>faecal impaction</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=faecal_impaction</link>
            <description>faecal impaction

see also:

	* constipation
	* laxatives

Introduction

	* constipation may lead to formation of large hard stools filling up the rectum which cannot be passed and which may cause overflow fecal incontinence and thus may present as diarrhoea
	* bowel distention from feacal overload may cause ischaemia of the bowel wall and cause</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Jun 2019 09:34:16 +0000</pubDate>
        </item>
        <item>
            <title>fascia lata / fascia iliacus nerve block</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fasciailiacusblock</link>
            <description>fascia lata / fascia iliacus nerve block

see also:

	* local anaesthetic agents
	* femoralNblock
	* fracture neck of femur (#NOF)
	* Anaesthesia UK - fascia iliacus block (pdf)

introduction

	* the fascia lata or fascia iliaca block is a high volume local anaesthetic block of both the femoral nerve and the lateral cutaneous nerve of the thigh via injection of low concentration,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 01 Aug 2013 06:22:12 +0000</pubDate>
        </item>
        <item>
            <title>Fasciola (liver flukes)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fasciola</link>
            <description>Fasciola (liver flukes)

see also:

	* parasites
	* the febrile returned traveller

Introduction

	* fasciola is a liver fluke (a type of parasitic worm) that can infect the liver and bile duct of exposed people and animals
	* two species can infect people:
		*  Fasciola hepatica: the main species that infects people.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 08 Jul 2024 05:56:52 +0000</pubDate>
        </item>
        <item>
            <title>Favourite links for users</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=favourites</link>
            <description>Favourite links for users

Victorian users and hospitals

	* Western Health favourite links
	* Royal Melbourne Hospital favourite links
	* Northern Hospital favourite links
	* StVH favourite links
	* Monash Medical Centre favourite links
	* Alfred Hospital favourite links
	* Austin Hospital favourite links
	* Eastern Health favourite links
	* Epworth favourite links
	* Ballarat Base Hopital favourite links
	* St John of God, Ballarat favourite links
	* Geelong Hospital favourite links
	* Bendigo…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Jan 2009 03:22:49 +0000</pubDate>
        </item>
        <item>
            <title>Austin Hospital ED favourite links</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=favourites_vic_austin</link>
            <description>Austin Hospital ED favourite links

see also:

	* Austin hospital information page in this wiki
	* Austin Hospital policies and procedures
	* Austin and Northern Hospitals ED education website
	* Western Health ED medical education and registrar training resource page
	* main index page

latest updates

	* Mx of critically severe paediatric asthma
	* the adult patient with chest pain in the ED

internet accessible

	* webmail
	* PBS - approved medications search

internet resources but only with…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 19 Aug 2009 02:32:40 +0000</pubDate>
        </item>
        <item>
            <title>Epworth Hospital ED favourite links</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=favourites_vic_epworth</link>
            <description>Epworth Hospital ED favourite links

see also:

	* welcome to the OzEMedicine Wiki
	* website 89 Bridge Rd Richmond 3121. ph: 9426 6666
	* Melbourne hospitals
measles outbreakmeasles
internet accessible

	* PBS - approved medications search

intranet only accessible</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 15 Apr 2009 05:46:35 +0000</pubDate>
        </item>
        <item>
            <title>Western Health ED main page</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=favourites_vic_wh</link>
            <description>Western Health ED main page
  Western Health ED medical rosters    WH Western Doctors Microsite     webmail     patient information sheets     TAC certificates     Worksafe certificates    MIMS    UpToDate    AMH    PBS    Therapeutic Guidelines        GOOGLE SEARCH    Vic Clinicians Health Channel     
see also:

	* ED life hacks
	* Western Health page on this wiki including links to specialty services
	* Western Health cardiology services 
	* Western Health radiology services including ultraso…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Feb 2026 03:34:44 +0000</pubDate>
        </item>
        <item>
            <title>Western Health favourite links</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=favourites_vic_wh2</link>
            <description>Western Health favourite links

	* main wiki index page
	* Western Health ED main page
	* webmail
	* patient information sheets (fact sheets)

see also:

	* Western Health page on this wiki including links to specialty services
	* Western Health cardiology services 
	* Western Health radiology services including ultrasound
	* Western Health Pathology Services - Dorevitch
	* Western Health ED nursing education resource page
	* Western Health ED medical education and registrar training resource pa…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Feb 2026 01:51:36 +0000</pubDate>
        </item>
        <item>
            <title>Western Health ED main page</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=favs2</link>
            <description>Western Health ED main page
  rosters    rosters       ptinfosheets    &lt;https://www.tac.vic.gov.au/providers/documents-and-forms/basic-forms/certificate-of-capacity&gt; TAC certificates    &lt;https://www.worksafe.vic.gov.au/resources/certificate-capacity-no-barcode&gt; Worksafe certificates    &lt;https://www.mimsonline.com.au.acs.hcn.com.au/Search/Search.aspx?acc=36265&gt;    &lt;http://spinfo.wh.org.au/plugins/library/goto_uptodate.asp&gt;    &lt;https://amhonline.amh.net.au.acs.hcn.com.au/drugs/monographs&gt;    &lt;http…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Feb 2026 01:48:57 +0000</pubDate>
        </item>
        <item>
            <title>full blood examination (FBE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fbe</link>
            <description>full blood examination (FBE)

see also:

	* anaemia
	* polycythaemia
	* febrile neutropenia 
		* defined as temperature &gt; 38ºC and absolute neutrophil count &lt; 0.5 × 10^9/L or &lt;1.0 x 10^9/L and falling rapidly

	* neutropenia
	* neutrophilia
	* lymphocytosis
	* monocytosis
	* lymphopenia
	* eosinophilia
	* eosinopenia
	* basophilopenia
	* thrombocytopenia
	* thrombocytosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 30 Dec 2013 06:28:52 +0000</pubDate>
        </item>
        <item>
            <title>removal of embedded fish hooks</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fb_fish_hooks</link>
            <description>removal of embedded fish hooks

see OzEmedicine blog on fish hook removal

see also:

	* foreign bodies in soft tissue / skin</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 Jan 2014 22:49:42 +0000</pubDate>
        </item>
        <item>
            <title>Ingested foreign bodies</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fb_ingested</link>
            <description>Ingested foreign bodies

	* see upper GIT foreign body</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 15 Nov 2011 06:38:31 +0000</pubDate>
        </item>
        <item>
            <title>Inhaled foreign bodies</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fb_inhaled</link>
            <description>Inhaled foreign bodies

see also cough

	* RCH guideline - inhaled foreign bodies</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 15:11:24 +0000</pubDate>
        </item>
        <item>
            <title>foreign bodies in soft tissue / skin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fb_soft_tissue</link>
            <description>foreign bodies in soft tissue / skin

see also:

	* removal of embedded fish hooks

introduction

	* failure to diagnose retained FB's in wounds are a common cause of medico legal issues
	* where open wound or puncture injuries are sustained with objects such as broken glass, efforts should be made to detect retained FB such as plain XR (although most glass does not show on Xrays), or better still, soft tissue ultrasound scan</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 Jan 2014 23:21:10 +0000</pubDate>
        </item>
        <item>
            <title>upper GIT foreign body</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fb_uppergit</link>
            <description>upper GIT foreign body

see also:

	* FB_lowerGIT

introduction

	* a large food bolus such as inadequately chewed meat, or accidental FB ingestion tend to become trapped at the following sites in the oesophagus:
		* upper oesophageal sphincter (cricopharyngeus)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 15 Nov 2011 06:42:34 +0000</pubDate>
        </item>
        <item>
            <title>febrile neutropenia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=febrile_neutropenia</link>
            <description>febrile neutropenia

see also:

	* sepsis / septicaemia
	* neutropenia
	* The febrile adult presenting to the ED
	* vancomycin
	* WH policy on febrile neutropenia Mx (docx)

introduction

	* DEFINED as temperature &gt; 38ºC and absolute neutrophil count &lt; 0.5 × 109/L or &lt;1.0 x 109/L and falling rapidly
	* although a subgroup of low-risk neutropenic patients may be able to be managed (at home) with oral therapy, most will need to be admitted for urgent empirical IV antibiotics regardless of their cl…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 19 Mar 2018 23:30:02 +0000</pubDate>
        </item>
        <item>
            <title>febuxostat</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=febuxostat</link>
            <description>febuxostat

see also:

	* gout

introduction

	* a xanthine oxidase inhibitor introduced in 2015, as a new Rx to lower uric acid levels in patients with chronic tophaceous gout
	* trials suggest it may be more effective than allopurinol but does risk cessation due to causing abnormal LFTs, and commencement needs to be covered with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Oct 2015 13:16:57 +0000</pubDate>
        </item>
        <item>
            <title>fentanyl</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fentanyl</link>
            <description>fentanyl

A short-acting parenteral  opiate analgesic.

The pharmacokinetics of fentanyl can be described by a three compartment model, with a distribution time of 1.7 minutes, redistribution of 13 minutes and a terminal elimination half-life of 219 minutes. The volume of distribution for fentanyl is 4 L/kg.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Aug 2011 11:21:27 +0000</pubDate>
        </item>
        <item>
            <title>ferritin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ferritin</link>
            <description>ferritin

see also:

	* iron deficiency anaemia
	* &lt;https://www.racgp.org.au/afp/2012/december/elevated-serum-ferritin/&gt;

introduction

low ferritin levels

	* iron deficiency anaemia

high ferritin levels

	* raised ferritin levels are not uncommon as there are many causes, and most cases are NOT due to hereditary haemochromatosis
	* patients with persistently raised ferritin levels without explanation should be considered for genetic testing for HFE mutations</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 26 May 2018 00:37:53 +0000</pubDate>
        </item>
        <item>
            <title>fetal macrosomia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fetal_macrosomia</link>
            <description>fetal macrosomia

see also:

	* Obstetrics
	* labour

introduction

	* fetal macrosomia is arbitrarily defined as a birth weight over 4000 g – 4500 g, or a fetus &gt;90th centile estimated fetal weight (EFW) for gestation or abdominal circumference (AC)
	* morbidity increases sharply beyond birth weights of 4,500g</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Apr 2013 06:44:35 +0000</pubDate>
        </item>
        <item>
            <title>foetal / fetal medicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fetal_medicine</link>
            <description>foetal / fetal medicine

see also:

	* pregnancy

Western Health's referral pathway 2013

	* referrals to WH fetal medicine outpatient clinic / genetic counsellor via fax to extension 50700 is appropriate for women with either:
		* confirmed foetal abnormality</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 17 Jun 2013 06:24:51 +0000</pubDate>
        </item>
        <item>
            <title>fever - the febrile response to infections</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fever</link>
            <description>fever - the febrile response to infections

see also:

	* the febrile child
	* The febrile adult presenting to the ED
	* antipyretics

why have a febrile response?

	* it is thought that the high body temperature in the febrile response helps fight off infections
		*  the febrile mechanism is found in 5 of the 7 classes of vertebrates and it appears to be increasing in complexity with evolution so it is probably helpful to survival</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 25 Dec 2022 07:35:58 +0000</pubDate>
        </item>
        <item>
            <title>The febrile adult presenting to the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fever_adult</link>
            <description>The febrile adult presenting to the ED

see also:

	* sepsis, SIRS and septic shock
	* infectious diseases
	* fever - the febrile response to infections
	* NSW CEC Sepsis Kills program
	* NSW CEC adult sepsis pathway chart (pdf) 

	* patients with severe sepsis or meningitis MUST have EARLY resuscitation and iv antibiotics within 60 minutes
	* patients on cytotoxic chemotherapy within past 2wks should be treated as per febrile neutropenia and triaged as 2 and given empirical antibiotics within 3…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 25 Dec 2022 07:36:55 +0000</pubDate>
        </item>
        <item>
            <title>the febrile child</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fever_paed</link>
            <description>the febrile child

see also:

	*  paediatric emergency medicine
	*  febrile convulsions
	*  antibiotics
	*  meningitis
	*  pneumonia
	*  urinary tract infections (UTIs) / cystitis
	*  osteomyelitis
	*  septic arthritis
	*  infectious diseases
	*  fever - the febrile response to infections
	*  sepsis /septicaemia in the paediatric patient
	* RCH guideline - febrile child &lt; 3yrs old
	* RCH guideline - illness in the returned traveler
	* RCH guideline - febrile neutropenia
	* NSW NETS - febrile chi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 06 Jul 2017 21:57:44 +0000</pubDate>
        </item>
        <item>
            <title>Fever with petechial or purpuric rash</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fever_purpura</link>
            <description>Fever with petechial or purpuric rash

see also:

	* meningitis
	* RCH guideline - febrile child with petechia/purpura
	* the petechial rash / purpura
	* necrotizing fasciitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 03 Jul 2013 04:12:40 +0000</pubDate>
        </item>
        <item>
            <title>fibroblast growth factors (FGF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fgf</link>
            <description>fibroblast growth factors (FGF)

see also:

	* cytokines
	* Platelet-derived growth factor (PDGF)
	* bone physiology

Introduction

	* FGFs are cytokines which may have autocrine, paracrine and endocrine actions
	* The fibroblast growth factor (FGF) family is a group of multifunctional signaling molecules that have a wide variety of functions.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Aug 2025 06:43:47 +0000</pubDate>
        </item>
        <item>
            <title>fibrinogen</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fibrinogen</link>
            <description>fibrinogen

see also:

	* anticoagulants
	* &lt;https://en.wikipedia.org/wiki/Fibrinogen&gt;

Introduction

	* a circulating glycoprotein synthesized in the liver which is converted by thrombin to fibrin to create a fibrin-based blood clot
		*  fibrin is broken down by plasmin to form D-Dimers

	* high serum levels may be a predisposing factor to</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Nov 2022 05:16:29 +0000</pubDate>
        </item>
        <item>
            <title>uterine fibroids (leiomyomas)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fibroids</link>
            <description>uterine fibroids (leiomyomas)

see also:

	* gynaecology

Introduction

	* uterine fibroids are common in women (present in 2-10% of pregnant women although this is likely an under-estimate due to difficulty in Dx, incidence of 40% - 60% by age 35 and 70% - 80% by age 50)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 02:19:10 +0000</pubDate>
        </item>
        <item>
            <title>fibromuscular dysplasia (FMD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fibromuscular_dysplasia</link>
            <description>fibromuscular dysplasia (FMD)

see also:

	* aortic dissection features and diagnosis
	* stroke (CVA)
	* connective tissue (CT) disorders

introduction

	* an uncommon angiopathy predisposing to dissection of medium sized arteries 
	* ~1% of middle aged women may have this condition affecting either renal arteries (60-75% of cases), craniocervical arteries (25-30% of cases, 95% of whom involved internal carotid mainly extracranially at C1-2 level, while 12-43% involve the vertebral arteries), vi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 03 Nov 2013 06:51:28 +0000</pubDate>
        </item>
        <item>
            <title>fibromyalgia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fibromyalgia</link>
            <description>fibromyalgia

see also:

	* wikipedia
	* rheumatology

introduction

	* During the 1980s, the term fibromyalgia came to the forefront in rheumatology and orthopedics. 
	* it is believed to be a primary autonomic nervous system dysfunction and is grouped as one of the dysautonomia syndromes 
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Apr 2010 09:33:00 +0000</pubDate>
        </item>
        <item>
            <title>filariasis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=filariasis</link>
            <description>filariasis

see also:

	* parasites
	* travel medicine
	* elephantiasis
	* wikipedia

introduction

	* filariasis are infectious tropical conditions caused by microfilariae (thread-like nematode parasites) belonging to the superfamily Filarioidea, which are spread by blood feeding arthropods such as black flies and mosquitoes.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 05 Jan 2012 04:54:14 +0000</pubDate>
        </item>
        <item>
            <title>fire and emergency procedures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fire</link>
            <description>fire and emergency procedures

see also:

	* aseptic non-touch technique (ANTT)

Introduction

•Remain calm and focused. Reassure and support others to remain calm.
•Raise the alarm by dialling 444 and providing the appropriate details to the switchboard. 
•On hearing a respond PA announcement, report to the area warden. For codes red, orange, purple, yellow and brown, the area warden can usually be found next to the red warden intercom phone (WIP) phone. 
•Follow the instructions of the area wa…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 07 Jun 2018 07:37:32 +0000</pubDate>
        </item>
        <item>
            <title>flail chest</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=flail_chest</link>
            <description>flail chest

see also:

	* fractured ribs
	* trauma to the chest

Introduction

	* the flail segment moves paradoxically (ie. moves in when the rest of the chest is expanding and out when the rest of the chest is moving in). 
		* this paradox will only be present in the spontaneously breathing patient, as mechanical ventilation will cause all segments to move the same way at the same time.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 06 Jul 2020 00:31:57 +0000</pubDate>
        </item>
        <item>
            <title>flecainide</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=flecainide</link>
            <description>flecainide

see also:

	* pre-excitation syndromes including WPW
	* supraventricular tachycardias (SVT)
	* atrial fibrillation

	* use of flecainide in patients with structural heart disease, and particularly those with ejection fraction &lt; 40% has been associated with life threatening and occasionally fatal ventricular arrhythmias.
	* thus flecainide should be avoided unless there is echocardiographic evidence of absence of structural heart disease or severe LVF</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 18 Sep 2012 08:53:48 +0000</pubDate>
        </item>
        <item>
            <title>illness following floods</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=floods</link>
            <description>illness following floods

see also:

	* insect bites and stings

Introduction

	* major flooding events have an enormous impact on local communities in particular
	* this impact may be further compounded by a range of illnesses that result from living in flooded / inundated areas or walking in flood waters, drinking flood contaminated water, use of generators for emergency power, mould exposures, etc</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Dec 2022 22:33:35 +0000</pubDate>
        </item>
        <item>
            <title>flucloxacillin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=flucloxacillin</link>
            <description>flucloxacillin

see also:

	* penicillins
	* antibiotics for Rx of Staph. aureus
dicloxacillin

introduction

	* flucloxacillin is a narrow spectrum penicillin active against Gram +ves including St. aureus
	* not active against Gram negative bacilli, methicillin resistant Staphylococcus, nor Streptococcus faecalis.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 09 Jan 2012 03:59:20 +0000</pubDate>
        </item>
        <item>
            <title>familial Mediterranean fever (FMF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fmfever</link>
            <description>familial Mediterranean fever (FMF)

see also:

	* the patient with acute abdominal pain in the ED

introduction

	* autosomal recessive hereditary condition characterised by episodes of fever and serosal inflammation causing abdominal pain or pleuritic chest pain or, particularly in North Africans,  synovitis and joint pain
	* mainly occurs in those descended from Sephardic Jews, Ashkenazi Jews, Armenians, Turks, North Africans, Arabs, and, less commonly, Greeks and Italians.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 14 Aug 2013 08:27:50 +0000</pubDate>
        </item>
        <item>
            <title>FODMAPs and the low FODMAP diet</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fodmap</link>
            <description>FODMAPs and the low FODMAP diet

see also:

	* irritable bowel syndrome (IBS)
	* healthy living and diets
	* Monash University - FODMAP diet and smartphone apps
	* &lt;http://www.npr.org/blogs/thesalt/2014/05/22/314287321/sensitive-to-gluten-a-carb-in-wheat-may-be-the-real-culprit?ft=1&amp;f=139941248&gt;

introduction

	* many gastroenterologists now believe that excessive levels of FODMAPs in the diet in at risk persons leads to symptoms of irritable bowel syndrome (IBS), and that reducing the level of …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 20 Jan 2019 19:38:05 +0000</pubDate>
        </item>
        <item>
            <title>folic acid / folate</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=folate</link>
            <description>folic acid / folate

se also:

	* vitamins

Introduction

	* folic acid is an essential micronutrient, mainly ingested from leafy vegetables

Folic acid deficiency

	* may cause:
		*  macrocytic anaemia
		*  neural tube birth defects


Folic acid supplementation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 10 Mar 2025 05:21:28 +0000</pubDate>
        </item>
        <item>
            <title>scalp folliculitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=folliculitis_scalp</link>
            <description>scalp folliculitis

see also:

	* dermatology
	* facial rashes
	* scalp and hair conditions

introduction

	* scalp pustules are a relatively common problem and often recurrent
	* there are many causes and the various conditions can be divided in to those causing superficial pustules or vesicles vs those causing deeper granulomas</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Feb 2026 09:38:09 +0000</pubDate>
        </item>
        <item>
            <title>foods that may be toxic or bad for you</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=foods_toxins</link>
            <description>foods that may be toxic or bad for you

see also:

	* toxinology
	* blue-green algae (BGA) toxins in waterways
	* food poisoning
	* air pollution and health risks
	* bio-accumulations and long term health
	* diets and healthy foods
	* Toxins (Basel). 2010 Sep Naturally Occurring Food Toxins

Introduction

	* anything taken too much is bad for you - even water and oxygen
	* foods can cause illness if:
		*  a person has a medically specific intolerance
		*  a person has an allergy -</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Apr 2026 04:08:55 +0000</pubDate>
        </item>
        <item>
            <title>food allergy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=food_allergy</link>
            <description>food allergy

see also:

	* allergy and hypersensitivity reactions
	* foods that may be toxic or bad for you

Introduction

	* immunoglobulin E (IgE)–mediated food allergy, the most common type of food allergy, often develops early in life, lasts a lifetime and can be life threatening and cause anaphylaxis
	* peanut and tree nuts are two of the most common foods that cause allergic reactions, and are the most persistent and dangerous, with the highest lifetime risk for anaphylaxis.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 09 Mar 2026 06:48:20 +0000</pubDate>
        </item>
        <item>
            <title>food bolus impaction in adults</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=food_impaction</link>
            <description>food bolus impaction in adults

ee also:

	* eosinophilic oesophagitis (EoE)
	* choking
	* gastroenterology
	* oesophageal rupture or perforation including Boerhaave syndrome

Introduction

	* impacted food bolus in the oesophagus usually occurs in adults with an underlying condition such as:
		*  eosinophilic oesophagitis (EoE) - this is thought to be the cause in around half the patients especially if there is a PH of asthma or hay fever</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 May 2024 06:31:01 +0000</pubDate>
        </item>
        <item>
            <title>food poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=food_poisoning</link>
            <description>food poisoning

see also:

	* gastroenteritis
	* The child with gastroenteritis
	* traveller's diarrhoea
	* diarrhoea

Introduction

	* illness after eating food may be caused by either:
		*  toxins in the food produced by bacterial contamination of the food
			*  symptoms tend to occur very soon after ingestion eg. Staph, E.coli toxins,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 23 Oct 2025 22:11:45 +0000</pubDate>
        </item>
        <item>
            <title>acute foot drop</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=foot_drop</link>
            <description>acute foot drop

see also:

	* the injured foot
	* sciatica
	* cauda equina syndrome (CES)
	* compartment syndrome

Introduction

	* acute foot drop is an uncommon presentation to the ED but often represents a genuine time critical emergency
	* foot drop is due to acute weakness of tibialis anterior (TA)
	* foot dorsiflexors are typically innervated by the L5 nerve root, but there may be considerable segmental overlap and anatomical variations, adding to the complexity of innervation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Jan 2020 12:08:32 +0000</pubDate>
        </item>
        <item>
            <title>the painful foot</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=foot_pain</link>
            <description>the painful foot

see also:

	* orthopaedics in the ED
	* the injured foot
	* ankle injuries and fractures

introduction

	* there are many common causes to foot pain
	* emergent causes to be considered include:
		* osteomyelitis - common in children as haematogenous spread, in others compound fracture is a more common cause
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 22 Jan 2026 06:42:08 +0000</pubDate>
        </item>
        <item>
            <title>forensic medicine, crimes and prisoners</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=forensic_med</link>
            <description>forensic medicine, crimes and prisoners

see also:

	* medico-legal issues in the ED

resources

	* ACEM paper - Forensic Testing and Examination in Emergency Departments (pdf)
	* Forensic and Medical Sexual Assault Clinicians Australia (FAMSACA)

Victoria

	* Vic. Institute Forensic Medicine (VIFP)
		* DNA testing - paternity, body identification, pre-natal, immigration
		* toxicology testing or expert opinion services
		* donor tissue bank
		* expert opinion
		* forensic medicine courses


Cri…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Jun 2017 05:33:06 +0000</pubDate>
        </item>
        <item>
            <title>paediatric limb fractures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fractures_paed</link>
            <description>paediatric limb fractures

see also:

	* orthopaedics in the ED
	* fractured distal radius in children
	* Bier's block - iv regional anaesthesia for LAMPs
	* scaphoid fracture
	* elbow fractures in children
	*  the child with a limp 
	* supracondylar fracture humerus in children

patient information sheets

	* see also patient information sheets
	* RCH - fractures (pdf)
	* RCH - plaster care (pdf)
	* Vic DHS - Fractures and plaster care (pdf)
	* Vic DHS - ankle sprains (pdf)
	* Vic DHS - Soft ti…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 May 2013 09:33:45 +0000</pubDate>
        </item>
        <item>
            <title>Bier's block - iv regional anaesthesia for LAMPs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fracture_biersblock</link>
            <description>Bier's block - iv regional anaesthesia for LAMPs

see also:

	* local anaesthetic agents
	* fractured distal radius in children
	* orthopaedics in the ED
	* EDTeaching.com's video on Bier's blocks
	* &lt;https://www.rch.org.au/clinicalguide/guideline_index/Bier_block/&gt;

introduction

	* LAMP is an abbreviation (Local Anaesthesia Manipulation and Plaster) for a procedure performed on a fractured bone or dislocated joint, where it is manipulated with the aid of a local anaesthetic</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Jan 2026 23:35:49 +0000</pubDate>
        </item>
        <item>
            <title>fractures and dislocations of the fingers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fracture_fingers</link>
            <description>fractures and dislocations of the fingers

see also:

	* fractures of the metacarpal
	* the injured hand

introduction

	* see the injured hand for guide to how to refer these injuries to the plastics team

crush injuries of finger-tip

	* these are extremely common injuries and if fracture of the distal phalanx is evident on XRay, then it can be assumed there is a significant nail bed injury associated, and if there has been any bleeding, it can be assumed, that the fracture is compound and at …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 03 Jul 2013 03:56:07 +0000</pubDate>
        </item>
        <item>
            <title>fractures of the metacarpal</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fracture_metacarpal</link>
            <description>fractures of the metacarpal

see also:

	* plastic surgery
	* the injured hand
	* fractures and dislocations of the fingers

introduction

	* ~30-40% of all fractures involving the hand are metacarpal fractures 

fracture neck 5th metacarpal

	* this is one of the most common fracture presentations to the ED
	* accounts for ~10% of all hand fractures</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 03 Jul 2013 03:46:32 +0000</pubDate>
        </item>
        <item>
            <title>elbow fractures in children</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fracture_paed_elbow</link>
            <description>elbow fractures in children

see also:

	* paediatric limb fractures
	* the acutely painful elbow
	* interpreting elbow Xrays - radiologyassistant.nl - this gives excellent explanations - just brilliant!</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 Apr 2012 06:20:46 +0000</pubDate>
        </item>
        <item>
            <title>fractured distal radius in children</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fracture_paed_radius_distal</link>
            <description>fractured distal radius in children

see also:

	* paediatric limb fractures
	* Bier's block - iv regional anaesthesia for LAMPs

introduction

	* please see paediatric limb fractures for general principles, analgesia and tips
	* any associated ulnar fracture can be managed on its merits (manipulated if angulated, otherwise ignored), EXCEPT in the very uncommon scenario of a Galeazzi fracture - dislocation of the distal radio-ulnar joint - these should be referred to ortho team for early Mx.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2009 08:43:11 +0000</pubDate>
        </item>
        <item>
            <title>supracondylar fracture humerus in children</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fracture_paed_supracondylar</link>
            <description>supracondylar fracture humerus in children

see also:

	* RCH guideline on supracondylar fractures and Gartland classification
	* paediatric limb fractures</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 May 2013 09:35:14 +0000</pubDate>
        </item>
        <item>
            <title>fractured ribs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fracture_ribs</link>
            <description>fractured ribs

see also:

	* trauma to the chest
	* flail chest

Introduction

	* fractured ribs are often well visualised on CXR, but may be poorly shown or not detectable on plain CXR or even rib views - ~50% of fractures are missed on CXR
	* patients with high impact injuries to the thorax (eg. fall from a roof), or high risk patients with poor respiratory reserve (eg. elderly), should have a low threshold for having a</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 09 Nov 2024 21:36:49 +0000</pubDate>
        </item>
        <item>
            <title>scaphoid fractures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fracture_scaphoid</link>
            <description>scaphoid fractures

see also:

	* orthopaedics in the ED
	* Ballarat ED Clinical Practice Guidelines for Mx of scaphoid fracture (pdf)
	* &lt;http://foam4gp.com/2013/11/15/foam4gp-map-scaphoid-fractures-thumbing-through-the-research/&gt;
	* &lt;http://lifeinthefastlane.com/scaphoid-fractures-the-ed-perspective/&gt;
	* UK patient information sheet - scaphoid fracture
	* BMJ 2013: Investigation of suspected scaphoid fractures

introduction

	* fracture of the scaphoid is a critical diagnosis to be made early …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 17 Dec 2015 22:51:42 +0000</pubDate>
        </item>
        <item>
            <title>fracture base of skull</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fracture_skull_basilar</link>
            <description>fracture base of skull

see also:

	* head injury in the adult patient
	* paediatric head injury
	* trauma

introduction

	* skull fracture indicates substantial force was involved
	* basilar skull fractures have a high incidence of intracranial haemorrhage
	* the following assumes other injuries have been managed and a primary and secondary survey carries out, in particular, cervical spine injury should be actively considered, as up to 15% of patients with skull fracture sustain a Cx spine frac…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 30 May 2017 06:16:59 +0000</pubDate>
        </item>
        <item>
            <title>fragile X</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fragilex</link>
            <description>fragile X

see also:

	* dementia

introduction

	* genetic disorders caused by mutation of the Fragile X mental retardation 1 gene (FMR1) gene on the X-chromosome
	* mutation at that site is found in 1 out of about every 2000 males and 1 out of about every 259 females.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 26 Jul 2011 08:03:18 +0000</pubDate>
        </item>
        <item>
            <title>frailty</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=frailty</link>
            <description>frailty

see also:

	* geriatrics
	* exercise for health

Introduction

	* frailty is the accumulation of deficits with ageing resulting in mobility issues, loss of independence
	* the level of frailty is an important factor in:
		*  falls risk
		*  depression due to mobility issues, loss of independence</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 06 Nov 2025 00:08:38 +0000</pubDate>
        </item>
        <item>
            <title>frostbite</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=frostbite</link>
            <description>frostbite

see also:

	* hypothermia

introduction

	* frostbite is necrosis of skin (usually extremities) resulting from a combination of cold-induced vasoconstriction and the low skin temperature itself and usually occurs when skin temperature falls below below −2°C</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 01 Aug 2020 12:01:44 +0000</pubDate>
        </item>
        <item>
            <title>fructose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fructose</link>
            <description>fructose

see also:

	* carbohydrates and sugars
	* obesity and weight management
	* diabetes mellitus

Introduction

	* fructose is a naturally occurring sugar found in many fruits and in honey
		*  apples and pears have a high amount of fructose and a high fructose:glucose ratio which may cause more malabsorption issues</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 20 Sep 2025 06:55:45 +0000</pubDate>
        </item>
        <item>
            <title>frusemide / furosemide / Lasix</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=frusemide</link>
            <description>frusemide / furosemide / Lasix

see also:

	* diuretics

introduction

	* a potent potassium losing loop diuretic mainly used in the Rx of congestive cardiac failure
	* inhibits sodium and chloride absorption in the ascending limb of Henle's loop and in both the proximal and distal tubules</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Dec 2015 05:11:19 +0000</pubDate>
        </item>
        <item>
            <title>follicle stimulating hormone (FSH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fsh</link>
            <description>follicle stimulating hormone (FSH)

see also:

	* gynaecology
	* luteinizing hormone (LH)
	* Inhibin
	* polycystic ovary syndrome (PCOS)

Introduction

	* FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland and, along with luteinizing hormone (LH), regulates the development, growth, pubertal maturation, and reproductive processes of the body, and in particular, stimulates the maturation of primordial germ cells required for ovulation and spermatogenesis.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 May 2024 03:14:19 +0000</pubDate>
        </item>
        <item>
            <title>fundoscopy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fundoscopy</link>
            <description>fundoscopy

see also:

	* ophthalmology
	* American Academy of Ophthalmology's EyeWiki

Introduction

	* fundoscopy can provide important clinical information for many emergency presentations as well as for detection of severity of chronic disease such as hypertension, diabetes, etc, however, it remains under-utilized in the ED for various reasons such as:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Dec 2024 05:45:50 +0000</pubDate>
        </item>
        <item>
            <title>fungi</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=fungi</link>
            <description>fungi

see also:

	* tinea fungal infections
	* microbiology
	* clinically important bacteria
	*  antibiotics
	*  antifungal agents

Introduction

	* the fungus kingdom consisting of some 2.2 million to 3.8 million species is separated from plant, bacteria, protozoa and animal kingdoms by the presence of chitin-glucan complexes in their cell walls</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Feb 2026 10:49:09 +0000</pubDate>
        </item>
        <item>
            <title>gabapentin (Neurontin)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gabapentin</link>
            <description>gabapentin (Neurontin)

see also:

	* neuropathic pain

Introduction

	* gabapentin is a gabapentinoid anticonvulsant neuropathic pain modulator commonly used in patients with chronic pain and those with focal seizures
	* 1st approved for use in the United Kingdom in 1993
	* pregabalin (Lyrica) is related in structure to gabapentin and has a similar activity and use profile</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 12:41:20 +0000</pubDate>
        </item>
        <item>
            <title>gabapentinoids</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gabapentinoids</link>
            <description>gabapentinoids

see also:

	* gabapentin (Neurontin)
	* pregabalin (Lyrica)
	* neuropathic pain
	* anticonvulsants</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 11 Jul 2025 06:33:12 +0000</pubDate>
        </item>
        <item>
            <title>gait disturbance</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gait</link>
            <description>gait disturbance

see also:

	* ataxia
	* normal pressure hydrocephalus
	* weakness of the lower limb(s) / weak in the knees
	* Parkinson's disease</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Aug 2019 07:14:59 +0000</pubDate>
        </item>
        <item>
            <title>gastroenteritis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gastroenteritis</link>
            <description>gastroenteritis

see also:

	* food poisoning
	* diarrhoea
	* The child with gastroenteritis
	* traveller's diarrhoea
	* dehydration
	* anti-emetics
	* the patient with acute abdominal pain in the ED

introduction

	* the diagnosis of gastroenteritis in the ED is essentially one of exclusion and generally requires both vomiting and diarrhoeal illness.
	* in Australia, it is the treating doctor's legal responsibility to notify the government of 2 or more cases</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 02 Feb 2020 15:00:40 +0000</pubDate>
        </item>
        <item>
            <title>gastroenterology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gastroenterology</link>
            <description>gastroenterology

see also:

	* Dyspepsia
	* upper GI bleeding
		*  oesophageal varices

	* pancreatitis
	* peptic ulcer disease
	* hepatitis
	* cirrhosis
	* portal hypertension
	* ascites
	* hepatic encephalopathy
	* coeliac disease
	* inflammatory bowel disease (IBD)
	* Crohn's disease
	* ulcerative colitis
	* colitis
	* lower GIT bleeding
	* gastroenterology at Western Health

podcasts and other resources

	* Video podcast - Acute Hemorrhagic Emergencies by Stuart Swadron (56min)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Aug 2018 08:25:34 +0000</pubDate>
        </item>
        <item>
            <title>The child with gastroenteritis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gastro_paed</link>
            <description>The child with gastroenteritis

see also:

	* paediatric emergency medicine
	* the febrile child
	* dehydration
	* gastroenteritis
	* RCH guideline - vomiting and diarrhoea
	* NSW NETS - gastroenteritis (pdf)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 07 Jul 2011 06:03:58 +0000</pubDate>
        </item>
        <item>
            <title>gallbladder polyps</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gb_polyps</link>
            <description>gallbladder polyps

see also:

	* biliary colic
	* gallbladder and bile duct tumours
	* more details of GB polyps, see &lt;https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359430/&gt;

Introduction

	* most are benign but as delayed diagnosis of malignancy is a poor prognosis, and even benign ones may become symptomatic, elective cholecystectomy may be indicated</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 31 Mar 2026 06:19:50 +0000</pubDate>
        </item>
        <item>
            <title>growth differentiation factor 15 (GDF15)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gdf15</link>
            <description>growth differentiation factor 15 (GDF15)

see also:

	* hormones
	* innate immunity
	* cachexia
	* anorexia

Introduction

	* the peptide hormone growth differentiation factor 15 (GDF15) wa discovered in 1997 and has been found to have a range of roles in physiology and pathophysiologic processes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Sep 2024 00:30:09 +0000</pubDate>
        </item>
        <item>
            <title>genetics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=genetics</link>
            <description>genetics

see also:

	* sex determination
	* DNA and genes
	* genomics

introduction

	* the human genome consists of ~3 billion (3×10^9) base pairs of DNA organized as 23 chromosomes of which:
		* 3% of which encodes genes:
			* “coding genes” can produce mRNA which is used to produce protein</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Aug 2025 00:45:41 +0000</pubDate>
        </item>
        <item>
            <title>sex determination</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=genetics_sex</link>
            <description>sex determination

see also:

	* genetics

Introduction

	* in all eutherian mammalian species including humans, sex determination is primarily based upon the genetic karyotype of XX for females and XY for males however, we now know there are many autosomal genes which are required to allow the bi-potential gonads to differentiate into either ovary or testes (or if it fails a non-functional or dysfunctional gonad - the</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 12 Jul 2019 16:40:23 +0000</pubDate>
        </item>
        <item>
            <title>gene regulation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gene_regulation</link>
            <description>gene regulation

see also:

	* micro RNAs (miRNAs)
	* DNA and genes

Introduction

	* for a cell to function properly, necessary proteins must be synthesized at the proper time.
	* gene regulation is the process used to control the timing, location and amount in which genes are expressed as RNA and as a result protein is produced</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Aug 2025 03:46:28 +0000</pubDate>
        </item>
        <item>
            <title>general medicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=genmed</link>
            <description>general medicine

	* heat illness and heat stroke
	* hypokalaemia
	* hyperkalaemia
	* hyponatraemia
	* diabetes mellitus
	* hypertension</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jan 2009 00:22:49 +0000</pubDate>
        </item>
        <item>
            <title>genomics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=genomics</link>
            <description>genomics

see also:

	* DNA and genes
	* risk and the perception of risk
	* the GIT microbiome
	* proteome
	* metabolome
	* exposome and health
	* transcriptome

Introduction

	* a patient's genomics generally refers to the individual patient's DNA and epigenetic modifications which can be found in the blood or in tissues and which may reflect impact a wide range of clinical responses, metabolic handling of medications, and risk for various diseases</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Aug 2025 00:37:16 +0000</pubDate>
        </item>
        <item>
            <title>general surgery</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gensurg</link>
            <description>general surgery

see also Main index

	* pre-operative assessment
	*  the patient with acute abdominal pain 
	* the child with abdominal pain
	* peritonitis
	* appendicitis
	* pancreatitis
	* diverticulitis
	* cholecystitis
	* ascending cholangitis
	* biliary colic
	* inflammatory bowel disease (IBD)
	* constipation
	* small bowel obstruction
	* large bowel obstruction
	* colitis
	* ischaemic colitis
	* caecal volvulus
	* sigmoid volvulus
	* colorectal cancer (bowel cancer)
	* peptic ulcer disea…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 05 Jan 2019 04:52:06 +0000</pubDate>
        </item>
        <item>
            <title>gentamicin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gentamicin</link>
            <description>gentamicin

see also;

	* antibiotics
	* aminoglycoside antibiotics
	* WH guideline - Gentamicin - Interval Adjustment Dosing Method for Adults (pdf) - WH intranet only
	* WH guideline - Gentamicin Administration in the Neonate and Child (pdf) - WH intranet only

introduction

	* belongs to the aminoglycoside antibiotics which were originally obtained from Streptomyces species
		* ototoxic &amp; nephrotoxic if high dose or prolonged use
		* active mainly against enteric Gram -ve bacteria
		* ATG rec…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Jul 2025 00:54:11 +0000</pubDate>
        </item>
        <item>
            <title>geriatrics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=geriatrics</link>
            <description>geriatrics

see also:

	* ageing
	* frailty
	* aged care index
	* geriatric trauma - trauma in the elderly
	* Geriatric depression scale
	* home care for the elderly
	* residential aged care - hostel and nursing home care
	* end of life care
	* delirium
	* fracture neck of femur (#NOF)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 24 Sep 2023 10:25:23 +0000</pubDate>
        </item>
        <item>
            <title>gamma hydroxybutyrate (GHB)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ghb</link>
            <description>gamma hydroxybutyrate (GHB)

see also:

	* drug dependency
	* addiction medicine (alcohol and other substance use)

introduction

	* a naturally occurring substance similar in structure to GABA, the neurotransmitter.
	* GHB is found in the brain, particularly in the basal ganglia, and readily crosses the blood brain barrier and placenta.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 30 May 2024 06:58:59 +0000</pubDate>
        </item>
        <item>
            <title>ghrelin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ghrelin</link>
            <description>ghrelin

see also:

	* insulin
	* cholecystokinin (CCK)
	* glucagon

Introduction

	* Ghrelin is a hormone released into circulation from the stomach and plays a key role in stimulating food intake by inhibiting vagal afferent firing.
	* Circulating ghrelin levels are increased by fasting and fall after a meal.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 13 Feb 2022 07:11:10 +0000</pubDate>
        </item>
        <item>
            <title>giardiasis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=giardiasis</link>
            <description>giardiasis

see also:

	* parasites
	* gastroenteritis
	* the febrile returned traveller

introduction

	* in humans is a diarrheal infection of the small intestine caused by a single-celled protozoan parasite Giardia lamblia.
	* giardiasis is caused by the ingestion of infective cysts
	* multiple modes of transmission, including person-to-person, water-borne (eg. hikers drinking contaminated stream water from cattle faeces), and venereal</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Dec 2015 22:14:53 +0000</pubDate>
        </item>
        <item>
            <title>ginger</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ginger</link>
            <description>ginger

see also:

	* anti-emetics
	* hyperemesis gravidarum

Introduction

	* ginger is the rhizome of Zingiber officinale) and is commonly used in foods and for motion sickness and as an antiemetic
	* in Turkey and nearby regions, ginger has also been used to enhance milk production in women who had vaginal births however, its use as a galactagogue has not been well studied</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 30 Sep 2024 06:14:28 +0000</pubDate>
        </item>
        <item>
            <title>gingivitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gingivitis</link>
            <description>gingivitis

see also:

	* dental
	* dental caries
	* periodontitis

Introduction

	* simple gingivitis is very common and painless and mainly due to poor dental hygiene - see periodontitis
	* acute ulcerative gingivitis is relatively common and painful, and usually caused by primary Herpes simplex virus (HSV) infection, or hand, foot and mouth infection in children</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2024 05:57:49 +0000</pubDate>
        </item>
        <item>
            <title>gastrointestinal stromal tumors (GIST)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gist</link>
            <description>gastrointestinal stromal tumors (GIST)

see also:

	* stomach cancer

Introduction

	* a rare type of GIT tumour (some are benign, some are malignant) believed to originate in cells found between muscle layers of the gastro-intestinal tract, called Interstitial cells of Cajal (ICC) and generally grow outwards</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Jul 2021 03:51:49 +0000</pubDate>
        </item>
        <item>
            <title>lower GIT bleeding</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gitbleeding_lower</link>
            <description>lower GIT bleeding

see also:

	* upper GIT bleeding
	* diverticulitis

introduction

	* bright red bleeding not mixed with stool after bowel actions which is present on the toilet bowel and/or toilet paper which resolves soon after and is not associated with haemodynamic instability is most likely to be</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 27 May 2013 02:12:40 +0000</pubDate>
        </item>
        <item>
            <title>upper GIT bleeding</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gitbleeding_upper</link>
            <description>upper GIT bleeding

see also:

	* AFTB Lectures - upper GIT bleeding (2008)
	* AFTB Lectures - oesophageal varices (2016)
	* lower GIT bleeding

Introduction

	* upper GIT bleeding is a potentially life threatening condition and may present as either:
		*  coffee ground vomits
		*  frank haematemesis
		*  melaena
		*  acute the shocked hypotensive patient or syncope / near syncope
		*  chronic or subacute iron deficiency anaemia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 13 Nov 2021 12:37:18 +0000</pubDate>
        </item>
        <item>
            <title>the GIT microbiome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=git_microbiome</link>
            <description>the GIT microbiome

see also:

	* gut-brain axis and the GIT microbiome
	* the oral microbiome
	* clinically important bacteria

	* the number of microorganisms that colonize the human body is 10 times the number of human body cells, and the number of microorganism genes is 150 times the number of human genes
	* in 2024, researchers, by leveraging cutting-edge proteogenomics and comparative genomics techniques to comprehensively annotate more than 964 million non-redundant smORFs across 75 habit…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Mar 2026 22:43:48 +0000</pubDate>
        </item>
        <item>
            <title>glaucoma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=glaucoma</link>
            <description>glaucoma

see also:

	* ophthalmology

introduction

	* aqueous humor is produced by the ciliary body in the posterior chamber of the eye. It diffuses from the posterior chamber, through the pupil, and into the anterior chamber. From the anterior chamber, the fluid is drained into the vascular system via the trabecular meshwork and Schlemm canal contained within the angle.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Oct 2013 07:42:13 +0000</pubDate>
        </item>
        <item>
            <title>glucagon-like peptide-1 (GLP-1) peptide analogs (eg. Ozempic)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=glp-1analogs</link>
            <description>glucagon-like peptide-1 (GLP-1) peptide analogs (eg. Ozempic)

see also:

	* oral hypoglycaemic agents
	* obesity and weight management
	* glucagon

Introduction

	* these peptides mimic the action of the incretin glucagon-like peptide-1 (GLP-1) and need to be given by s/c injection
	* patients with pre-diabetes or type 2 diabetes mellitus often have defects in the effect of incretin</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Feb 2026 11:35:48 +0000</pubDate>
        </item>
        <item>
            <title>glucagon</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=glucagon</link>
            <description>glucagon

see also:

	* hormones
	* insulin

introduction

	* a peptide hormone, produced by alpha cells of the pancreas, that raises blood glucose levels by stimulating gluconeogenesis and glycogenolysis in the liver, and turns off glycolysis
	* it can be also given parenterally to Rx</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 11 May 2014 12:43:45 +0000</pubDate>
        </item>
        <item>
            <title>glomerulonephritis (GN)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gn</link>
            <description>glomerulonephritis (GN)

see also:

	* nephrotic syndrome
	* renal medicine (nephrology)

introduction

	* inflammation of the renal glomeruli with virtually all forms being mediated by an immune process (except for Alport's syndrome and TGBM disease)
	* spectrum ranges from:
		* asymptomatic cases</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 28 Oct 2013 07:49:22 +0000</pubDate>
        </item>
        <item>
            <title>gonadotrophin releasing hormone agonists (GnRH agonists)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gnrh_agonists</link>
            <description>gonadotrophin releasing hormone agonists (GnRH agonists)

see also pharmacology main index; endometriosis; anti-androgens

	* PBS Nafarelin product information (pdf)

pharmacology

	* GnRH agonists stimulate release of pituitary gonadotrophins LH and FSH, with consequent initial increase of ovarian and testicular steroidogenesis.
	* continuous dosing rather than physiologic pulsatile dosing gradually abolishes the stimulatory effect on the pituitary gland.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 29 Jan 2014 01:09:39 +0000</pubDate>
        </item>
        <item>
            <title>gonococcus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gonococcus</link>
            <description>gonococcus

see also:

	* clinically important bacteria
	* pelvic inflammatory disease (PID)
	* sexually transmitted infections (STDs/STIs)
	* epididymo-orchitis
	* wikipedia

introduction

	* the gonococcus (Neisseria gonorrhoeae) is an obligate aerobe, bean-shaped diplococcus, fastidious, oxidase +ve Gram -ve coccoid discovered in 1879
	* it is transmitted by sexual contact and co-infections with other causes of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 10 Nov 2023 01:13:50 +0000</pubDate>
        </item>
        <item>
            <title>gastro-oesophageal reflux</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gor</link>
            <description>gastro-oesophageal reflux

see also:

	* Dyspepsia
	* oesophagitis in adults
	* eosinophilic oesophagitis (EoE)
	* oesophageal cancer
	* gastroenterology
	* the adult patient with chest pain in the ED

introduction

	* often abbreviated as GOR, GORD or GERD (gastro-esophageal reflux disease)
	* one of the most common causes of retrosternal chest pain often confused with cardiac pain, hence its common name - heartburn</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 27 May 2024 23:35:11 +0000</pubDate>
        </item>
        <item>
            <title>Gastro-oesophageal reflux in infants</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gor_infants</link>
            <description>Gastro-oesophageal reflux in infants

	* RCH guideline - GOR in infants</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 15:13:16 +0000</pubDate>
        </item>
        <item>
            <title>gout</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gout</link>
            <description>gout

see also:

	* colchicine
	* non-steroidal anti-inflammatory drugs (NSAIDs)
	* uricosuric agents
	* hyperuricaemia
	* allopurinol
	* urolithiasis / renal stones / renal calculi

historical perspective

	* Described by Hippocrates
	* Podagra was the foot goddess, a bad tempered virgin, who attacked victims after they overindulged.
	* Autumn crocus used to Rx arthritis in 6th Century
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 Jan 2026 10:29:59 +0000</pubDate>
        </item>
        <item>
            <title>online bookings for GPs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gpbookings</link>
            <description>online bookings for GPs

see:

	* Medical One bookings
	* Health Engine search and online bookings for GP's Australia wide
		* only includes practices which have signed up, thus Medical One is not included
		* eg. appointments available today near St Albans, Vic</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Jul 2016 18:17:16 +0000</pubDate>
        </item>
        <item>
            <title>Graves disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=graves</link>
            <description>Graves disease

see also:

	* thyroid physiology and hormones
	* hyperthyroidism
	* Mx of a low TSH
	* thyroid storm
	* thyroiditis

Introduction

	* Graves-Basedow thyroiditis is an autoimmune disease affecting the thyroid gland which results in “toxic diffuse goitre” and a range of clinical features including hyperthyroidism
	* accounts for 50-80% of cases of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Oct 2021 07:15:15 +0000</pubDate>
        </item>
        <item>
            <title>groin pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=groin_pain</link>
            <description>groin pain

see also:

	* back pain in the ED
	* flank pain
	* hip pain

introduction

	* there are a multitude of causes of groin pain
	* the ED clinician needs to systematically exclude the more serious causes such as abdominal aortic aneurysm (AAA), strangulated groin herniae +/- bowel obstruction, and acute scrotal pain or swelling such as torsion testes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 06 Oct 2022 02:36:12 +0000</pubDate>
        </item>
        <item>
            <title>Grover's disease (transient acantholytic dermatosis)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=grover</link>
            <description>Grover's disease (transient acantholytic dermatosis)

see also:

	* acute rashes in adults

Introduction

	*  a common acquired itchy mainly truncal rash characterised by acantholysis 
		*  described by Grover in 1970

Epidemiology

	*  most often affects Caucasian men over 50 years of age with sundamaged skin</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Jul 2022 07:26:57 +0000</pubDate>
        </item>
        <item>
            <title>Guillain-Barre syndrome (GBS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=guillain-barre</link>
            <description>Guillain-Barre syndrome (GBS)

see also:

	* weakness of the lower limb(s) / weak in the knees
	* Vic. Better Health Channel patient information on GBS
	* NINDS information page on GBS
	* wikipedia

introduction

	* aka Landry's ascending paralysis
	* Guillain-Barré syndrome is an acute onset autoimmune demyelinating condition which appears to be triggered by viral or bacterial infections, particularly</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 27 Sep 2013 05:13:29 +0000</pubDate>
        </item>
        <item>
            <title>gut-brain axis and the GIT microbiome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gut-brain</link>
            <description>gut-brain axis and the GIT microbiome

see also:

	* the brain
	* the GIT microbiome

Introduction

	* the gut-brain axis links emotional and cognitive centers of the brain with peripheral intestinal functions which is modulated by gut microbiome - microbiota and GBA appears to be bidirectional, through signaling from gut-microbiota to brain and from brain to gut-microbiota by means of neural, endocrine, immune, and humoral links</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Nov 2025 10:11:26 +0000</pubDate>
        </item>
        <item>
            <title>gynaecology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gynaecology</link>
            <description>gynaecology

	* Royal Australian &amp; NZ College of Obstetricians and Gynaecologists - college statements and guidelines
		* RANZCOG guideline Ix of intermenstrual and post-coital bleeding (pdf)
		* RANZCOG guideline Mx of menopause (pdf)
		* Statement on anticoagulation in pregnancy &amp; puerperium
		* RANZCOG - termination of pregnancy
		* MJA 2009 - A consensus statement on the management of pregnancy and delivery in women who are carriers of or have bleeding disorders such as haemophilia

	* RIF o…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 02:11:55 +0000</pubDate>
        </item>
        <item>
            <title>potential complications of gynaecologic surgery</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gynaesurgery_complications</link>
            <description>potential complications of gynaecologic surgery

see also:

	* gynaecology

Introduction

	* depending upon the type of procedure, potential local complications of surgery include:
		*  UTI
		*  urinary retention
		*  uterine issues
			*  vault haematoma post-hysterectomy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 03 Sep 2025 10:30:38 +0000</pubDate>
        </item>
        <item>
            <title>a guide to a healthy vagina</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=gynae_health</link>
            <description>a guide to a healthy vagina

see also:

	* gynaecology

a gynaecologist's tips for reducing vulval irritation

	* see https://jeanhailes.org.au/contents/documents/Resources/Booklets/The_vulva.pdf - Jean Hailes Women's Health - patient information booklet on vulval health care for women (pdf) for more details
	* Don’t use any soap or perfumed bath products to wash your vulva – only use water or soap substitute
	* Never use talcum powder on your vulva (seems it may increase risk of ovarian cancer)…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 11 Sep 2017 23:40:55 +0000</pubDate>
        </item>
        <item>
            <title>hereditary angioedema (HAE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hae</link>
            <description>hereditary angioedema (HAE)

see also:

	* allergy and hypersensitivity reactions
	* angioedema
	* anaphylaxis
	* RCH guideline - angioedema - C1 esterase inhibitor deficiency
	* at Western Health, icatibant is available after hours in the night store and accessible by the AHA

introduction

	* hereditary angioneurotic oedema is an autosomal dominant condition caused by either a reduced (type I) or dysfunctional (type II) C1-esterase inhibitor (C1-INH) which is a blood protein enzyme which norma…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:40:30 +0000</pubDate>
        </item>
        <item>
            <title>haematemesis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haematemesis</link>
            <description>haematemesis

see also:

	* upper GIT bleeding

Introduction

	* haematemesis is blood in vomitus from upper GIT bleeding, lesser severity may produce “coffee-gounds” vomitus of altered blood
	* it may or may not be associated with melaena</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Jun 2019 05:36:33 +0000</pubDate>
        </item>
        <item>
            <title>haematology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haematology</link>
            <description>haematology

see also:

	* anaemia
		* iron deficiency anaemia
		* vitamin B12 (cobalamin)
		* haemolytic anaemia
		* sickle cell disease (SCD)
		* thalassemia
		* aplastic anaemia / pancytopenia
		* paroxysmal nocturnal haemoglobinuria

	* leukaemia
	* lymphoma
	* myeloproliferative disorders
	* multiple myeloma
	* myelofibrosis
	* thrombocytopenia
		* Idiopathic thrombocytopenic purpura (ITP)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 Oct 2021 05:19:39 +0000</pubDate>
        </item>
        <item>
            <title>haematuria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haematuria</link>
            <description>haematuria

see also:

	*  urinary tract infections (UTIs) / cystitis
	*  urology
	*  renal medicine
	* RCH guideline - haematuria

aetiology by site

haematologic

	* coagulopathy
	* sickle haemoglobinopathies

glomerular (esp. if glomerular RBCs &amp;/or red cell casts)

	* primary glomerular disease
	* multisystem disease:
		* SLE, HSP, HUS, PAN, Wegener's granulomatosis, Goodpasture's syndrome</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 02 Jul 2022 01:09:49 +0000</pubDate>
        </item>
        <item>
            <title>haemochromatosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haemochromatosis</link>
            <description>haemochromatosis

see also:

	* liver diseases
	* iron poisoning
	* haemosiderosis

Introduction

	* the excessive accumulation of iron in the body due to a homozygous recessive inherited disorder that causes excessive iron absorption from the gut
		* NB. “secondary haemochromatosis” due to acquired causes is called</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 Nov 2023 22:31:09 +0000</pubDate>
        </item>
        <item>
            <title>haemopericardium</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haemopericardium</link>
            <description>haemopericardium

see also:

	* pericarditis
	* cardiac tamponade
	* trauma

Introduction

	* hemopericardium is blood within the pericardial sac
	* death is generally more likely to be caused by the cause of the haemopericardium rather than by the effects of the haemopericardium although if it collects rapidly it may of itself cause death through</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 24 Aug 2019 12:18:05 +0000</pubDate>
        </item>
        <item>
            <title>Haemophilia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haemophilia</link>
            <description>Haemophilia

	* RCH guideline - haemophilia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 22:35:11 +0000</pubDate>
        </item>
        <item>
            <title>haemoptysis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haemoptysis</link>
            <description>haemoptysis

see also:

	* acute cough in the adult

Introduction

Is it really haemoptysis?

	* pseudohemoptysis
			* blood coming from the upper airways eg. posterior epistaxis, sinusitis, 

		* haematemesis
			* pH &lt; 7, blood is dark red or brown not bright red


aetiology</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jul 2021 23:18:04 +0000</pubDate>
        </item>
        <item>
            <title>The Gunnar-Thevathasan haemorrhagic crescent sign</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haemorrhagic_crescent_sign</link>
            <description>The Gunnar-Thevathasan haemorrhagic crescent sign

	* Eponymous signs and syndromes abound..
	* This one can be diagnosed in the ED when the history of soft tissue injury of the patient's knee is followed by the appearance of a haemorrhagic crescent under the ipsilateral malleoli days to weeks later. The patient may be concerned that they have a DVT because of calf swelling or pain, but this is NOT a DVT.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 08 Dec 2014 02:52:22 +0000</pubDate>
        </item>
        <item>
            <title>haemorrhoids</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haemorrhoids</link>
            <description>haemorrhoids

see also:

	* ano-rectal pain
	* World J Gastroenterol. 2012: Hemorrhoids: From basic pathophysiology to clinical management

Introduction

	* haemorrhoidal issues affect up to a third of adults and is most prevalent in 45-65 yr olds while being uncommon under 20 yrs old
	* internal “primary” haemorrhoids
		* form due to congestion of the superior haemorrhoidal venous plexus resulting in prolapse of the mucosa above the dentate line</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2026 03:46:56 +0000</pubDate>
        </item>
        <item>
            <title>haemosiderosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haemosiderosis</link>
            <description>haemosiderosis

see also:

	* liver diseases
	* iron poisoning
	* haemochromatosis

Introduction

	* the excessive accumulation of iron in the body due to an acquired cause and often called “secondary haemochromatosis”
		* NB. “primary haemochromatosis” is due to an homozygous recessive inherited disorder that causes excessive iron absorption from the gut</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 Nov 2023 22:58:12 +0000</pubDate>
        </item>
        <item>
            <title>hallux valgus (bunions)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hallux_valgus</link>
            <description>hallux valgus (bunions)

see also:

	* orthopaedics in the ED

introduction

	* bunions are a common genetic condition with incidence increasing with age:
		* 3% in persons aged 15-30 years
		* 9% in persons aged 31-60 years 
		* 16% in those older than 60 years

	* of those under age 60 years, ~90% are genetic</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 02 Feb 2013 13:33:26 +0000</pubDate>
        </item>
        <item>
            <title>haloperidol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haloperidol</link>
            <description>haloperidol

see also:

	* anti-psychotic medications

introduction

	* droperidol is a butyrophenone type antipsychotic agent which is similar to droperidol (Droleptan)
	* it produces marked tranquillization and sedation as well as having an anti-emetic effect
	* it potentiates other CNS depressants
	* also produces mild alpha-adrenergic blockade, peripheral vascular dilatation,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 May 2014 07:00:37 +0000</pubDate>
        </item>
        <item>
            <title>hand hygiene for health workers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hand_hygiene</link>
            <description>hand hygiene for health workers

see also:

	* aseptic non-touch technique (ANTT)
	* prevention of infection in healthcare - standard precautions
	* clinically important bacteria
	* NHHI staff Hand hygiene mandatory competency module for Australian healthcare workers

Introduction

	* Micro-organisms are transmitted from one patient to another via a healthcare worker's hands (HCW) in 5 sequential steps:
		* organisms on patient's skin or shed onto surrounding objects (fomites)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 Nov 2023 09:24:49 +0000</pubDate>
        </item>
        <item>
            <title>hantavirus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hantavirus</link>
            <description>hantavirus

see also:

	* &lt;https://www.cdc.gov/hantavirus/&gt;

Introduction

	* Hantaviruses are a family of viruses spread mainly by rodents and can cause varied disease syndromes in people worldwide.  
	* Infection with any hantavirus can produce hantavirus disease in people. 
	* Hantaviruses in the Americas are known as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 27 Jan 2020 19:26:39 +0000</pubDate>
        </item>
        <item>
            <title>History of use of anti-arrhythmic agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hantiarrhythmics</link>
            <description>History of use of anti-arrhythmic agents

see also: antiarrythmics, pharmacology main index, historic perspectives of medicine

History of anti-arrhythmic drugs:

	* Noted that pts on cinchona for malaria treatment were occasionally cured of AF - the 1st recorded use of this was in 1749 by Jean-Baptiste de Sénac.
	* Wenckeback (1914) reported on effects of quinine alkaloids in certain arrhythmias which impressed Frey (1918) who studied use of cinchonine, quinine &amp; quinidine in AF &amp; found quinidi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 28 Aug 2008 07:45:51 +0000</pubDate>
        </item>
        <item>
            <title>happiness</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=happiness</link>
            <description>happiness

see also:

	* depression
	* sadness
	* stress
	* Aust. survey on well-being 2015
	* Youtube 1hr lecture - science of happiness



what is happiness?

	* Subjective wellbeing or happiness = self-reported (high positive mood + low negative mood + high life satisfaction)
	* overall most people are happy by nature and remain around this baseline unless there are chronic conditions which reduce happiness such as unemployment, disability, dysharmony,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 May 2017 08:58:09 +0000</pubDate>
        </item>
        <item>
            <title>haptoglobin (Hp)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=haptoglobin</link>
            <description>haptoglobin (Hp)

see also:

	* haemolytic anaemia
	* lactic dehydrogenase (LDH)

Introduction

	* serum haptoglobin is used as a marker of haemolytic anaemia and is also an acute phase reactant
	* haptoglobin binds free haemoglobin and the complexes are then removed from circulation by the reticuloendothelial system, mostly, by the spleen.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 May 2018 23:35:58 +0000</pubDate>
        </item>
        <item>
            <title>HAS-BLED bleeding risk scoring tool for anticoagulation Rx</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=has-bled</link>
            <description>HAS-BLED bleeding risk scoring tool for anticoagulation Rx

see also:

	* antithrombotic Rx for prevention of stroke
	* warfarin
	* general anticoagulation guidelines
	* MDCALC online calculator

introduction

	* anticoagulant bleeding risk scoring systems are generally quite complex
	* HAS-BLED appears to be the scoring tool that is currently recommended</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 04 Apr 2014 06:05:46 +0000</pubDate>
        </item>
        <item>
            <title>hepatitis B virus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hbv</link>
            <description>hepatitis B virus

see also:

	* viruses
	* hepatitis C virus
	* hepatitis
	* cirrhosis
	* hepatocellular carcinoma

hepatitis B

	* Aust. Prescriber 2009 - The management of hepatitis B

transmission

	* highly transmissible if no vaccination (~10x more infectious than with similar exposure to hepatitis C virus and ~100x more infectious than needlestick exposures to HIV / AIDS)
	* can occur via a number of routes - percutaneous (needlestick, IVDU, tatooing, or body piercing), parenteral (transf…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 Jan 2025 22:49:43 +0000</pubDate>
        </item>
        <item>
            <title>hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hcnblockers</link>
            <description>hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers

see also:

	* congestive cardiac failure
	* beta adrenergic blockers

Introduction

	* hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers are used to Mx congestive cardiac failure

Pharmacology

	* hyperpolarization-activated cyclic nucleotide-gated (HCN) channels</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 02:54:22 +0000</pubDate>
        </item>
        <item>
            <title>hepatitis C virus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hcv</link>
            <description>hepatitis C virus

see also:

	* viruses
	* hepatitis B virus
	* HIV / AIDS
	* hepatitis
	* cirrhosis
	* hepatocellular carcinoma

introduction

	* a single-stranded ribonucleic acid (RNA) hepacivirus, a member of the flaviviridae viruses
	* the most frequent cause of parenteral non-A, non-B hepatitis worldwide. 
	* causes 20% of acute viral hepatitis cases in USA.
	* mainly spread by blood transmission, primarily from sharing needles between</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Oct 2023 02:50:47 +0000</pubDate>
        </item>
        <item>
            <title>headache</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=headache</link>
            <description>headache

see also:

	* meningitis
	* the child with headache
	* subarachnoid haemorrhage (SAH)
	* migraine
	* acute unilateral headache
	* cervicogenic headache
	* a diagnostic approach to the adult with acute headache
	* AFTB lectures - headache

introduction:

	* patients with headache as a prime feature are a worrying group of patients as there are a number of potentially life threatening or morbid conditions that, although uncommon, are easily missed:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 12 Mar 2025 23:11:45 +0000</pubDate>
        </item>
        <item>
            <title>cervicogenic headache</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=headache_cervicogenic</link>
            <description>cervicogenic headache

see also:

	* headache
	* migraine

Introduction

	* headaches arising from irritation in the upper neck are very common and can cause unilateral temporal/retro-orbital headaches as well as occipital headaches and can precipitate migraine
	* a common site of irritation is at C2/3 or C3/4 facet joints which are postero-lateral and often involved in degenerative or arthritic pathology, or acutely if prolonged stresses are applied such as during sleep, holding phone by the he…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 Feb 2024 02:37:37 +0000</pubDate>
        </item>
        <item>
            <title>cluster headache</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=headache_cluster</link>
            <description>cluster headache

see also:

	* acute unilateral headache

introduction

	* recurrent clusters of sudden onset lancinating retro-orbital headaches lasting minutes to 3 hours usually occurring in the early hours of the morning (perhaps REM sleep mediated) causing the patient to become agitated, restless and walk around</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 16 Sep 2016 06:18:20 +0000</pubDate>
        </item>
        <item>
            <title>a diagnostic approach to the adult with acute headache</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=headache_dx</link>
            <description>a diagnostic approach to the adult with acute headache

	* the following is a STEPWISE diagnostic algorithm provided as an AID to diagnosis of headache in the adult patient - one should not just jump to step x without considering each of the preceding steps</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 25 Aug 2024 01:57:16 +0000</pubDate>
        </item>
        <item>
            <title>The child with a headache</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=headache_paed</link>
            <description>The child with a headache

see paediatric emergency medicine, meningitis, headache, child with head injury, sinusitis, migraine

	* RCH guideline - headache</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 04:12:30 +0000</pubDate>
        </item>
        <item>
            <title>post LP headaches (PLPH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=headache_postlp</link>
            <description>post LP headaches (PLPH)

see also:

	* headache

introduction

	* occurs in 18-32% of patients who undergo lumbar puncture
			* PLPH is believed to be caused by adenosine-induced cerebral vasodilatation
			* usually starts within 48hrs (but not within 1hr) of lumbar puncture or epidural procedures although may be delayed for up to 14 days.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 Apr 2013 07:11:24 +0000</pubDate>
        </item>
        <item>
            <title>acute unilateral headache</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=headache_unilateral</link>
            <description>acute unilateral headache

see also:

	* headache

introduction

	*  is there a Horner's syndrome present?
			* consider internal carotid artery dissection which needs emergency Ix 
			* if male and occurring at night, consider cluster headache 

		*  is there ant/lateral neck pain, new tinnitus or monocular blindness?</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 18 Jan 2025 21:36:18 +0000</pubDate>
        </item>
        <item>
            <title>head injury in the adult patient</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=head_injury_adult</link>
            <description>head injury in the adult patient

see also:

	* trauma
	* paediatric head injury
	* concussion
	* patient information sheets - head injury
	* Monash Concussion Clinic for children and adults - a low cost clinical psychology/neuropsychology service - an income tested sliding fee applies
	* Serum glial fibrillary acidic protein levels are 97% accurate up to 7 days post injury of detecting brain injury such as concussion</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Jul 2025 08:02:33 +0000</pubDate>
        </item>
        <item>
            <title>paediatric head injury</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=head_injury_paed</link>
            <description>paediatric head injury

see also:

	* paediatric emergency medicine
	* RCH guideline - head injury
	* NSW NETS - head injury (pdf)
	* head injury in the adult patient
	* Monash Concussion Clinic for children and adults - a low cost clinical psychology/neuropsychology service - an income tested sliding fee applies
	* Serum glial fibrillary acidic protein levels are 97% accurate up to 7 days post injury of detecting brain injury such as concussion</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Mar 2016 21:21:36 +0000</pubDate>
        </item>
        <item>
            <title>healthy living and diets</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=healthy_living</link>
            <description>healthy living and diets

see also:

	* diets and healthy foods
	* salt / sodium in food products

healthy living

	* do not smoke
	* do not abuse substances
		*  these will generally take you down a dark path you may not get back from - there are no easy ways of managing the hardships of life - substances will only make them worse</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 12 Dec 2025 07:03:46 +0000</pubDate>
        </item>
        <item>
            <title>heat rash / miliaria rubra</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=heatrash</link>
            <description>heat rash / miliaria rubra

see also:

	* acute rashes in adults
	* urticaria

Introduction

	* an annoying “prickly” rash mainly involving flexures wear sweat tends to collect in response to prolonged hot humid conditions
	* common in those travelling to tropical areas when it mainly affects areas covered by clothing</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Jul 2022 11:13:13 +0000</pubDate>
        </item>
        <item>
            <title>heat waves</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=heatwaves</link>
            <description>heat waves

see also:

	* Vic DHS patient information sheet - preventing heat stress
	* Vic DHS community resources for managing heatwaves
	* WH preparing for heatwaves (intranet only)
	* heat illness and heat stroke

introduction

	* heat waves are common in Australia
	* in the southern parts of Australia, they are particularly a problem in January when 3-7 days in a row of 40degC or more are possible
	* such heat waves are associated with an increase in mortality, particularly of the elderly w…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 15 Aug 2018 09:29:04 +0000</pubDate>
        </item>
        <item>
            <title>heat illness and heat stroke</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=heat_illness</link>
            <description>heat illness and heat stroke

see also:

	* Vic DHS patient information sheet - preventing heat stress
	* Vic DHS community resources for managing heatwaves
	* heat waves
	* hyperthermia
	* malignant hyperthermia
	* hypothermia

introduction

	* heat illness encompasses a spectrum of severity including:
		* heat oedema
		* heat rash (prickly heat)
		* heat cramps
		* tetany
		* heat syncope
		* heat exhaustion</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 07:16:22 +0000</pubDate>
        </item>
        <item>
            <title>heavy metals</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=heavy_metals</link>
            <description>heavy metals

see also:

	* foods that may be toxic or bad for you
	* toxicology

Introduction

	* heavy metals are generally regarded as toxins, particularly as they tend to be poorly eliminated and thus tend to accumulate with chronic exposures resulting in cellular toxicities
	* there is no formal definition of a heavy metal but tends to be context-driven such as in toxicology, but they are generally metals with a density &gt; 10 g/cm³ such as lead (11.3g/cm³) and mercury (13.5g/cm³) although ar…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Jan 2026 04:44:09 +0000</pubDate>
        </item>
        <item>
            <title>Helicobacter pylori infection</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=helicobacter_pylori</link>
            <description>Helicobacter pylori infection

see also clinically important bacteria; gastro-oesophageal reflux; peptic ulcer disease; Dyspepsia;

Introduction

	* H. pylori is the dominant factor in the multifactorial disease peptic ulceration &amp; its eradication should decrease incidence of DU in humans by over 90%;
	* Most people infected with H. pylori are asymptomatic but infection confers a lifetime risk of peptic ulcer disease of 15% to 20%, and of gastric cancer of up to 2%.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 07 Jan 2014 05:39:14 +0000</pubDate>
        </item>
        <item>
            <title>HELLP syndrome in pregnancy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hellp</link>
            <description>HELLP syndrome in pregnancy

see also:

	* liver function tests (LFTs)
	* pre-eclampsia and eclampsia

introduction

	* HELLP is an acronym for the 3 main features:
		* haemolysis
		* elevated liver enzyme levels
		* low platelet level

	* it is a potentially life threatening complication of pregnancy
	* occurs in ~ 1 in 300 pregnancies, and in up to 12% of cases of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Jun 2024 09:22:05 +0000</pubDate>
        </item>
        <item>
            <title>hepatitis A</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hepa</link>
            <description>hepatitis A

see also:

	* hepatitis
	* Vic Health - information on hep A
	* Vic Health - health alerts

introduction

	* currently there is an outbreak in Australia due to imported frozen berries (Feb 2015), so have a low index of suspicion.

clinical presentation

	* incubation period is 15 to 50 days.
	* transmission occurs via the faecal-oral route through the ingestion of contaminated food or water, or through direct hand-to-mouth contact with the faeces of an infectious case.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Mar 2015 23:27:49 +0000</pubDate>
        </item>
        <item>
            <title>heparin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=heparin</link>
            <description>heparin

see:

	* anticoagulants,
	* Historical perspective of anticoagulants
	* pharmacology main index
	* warfarin
	* enoxaparin
	* RCH guidelines - anticoagulation therapy in children

Clinical usage:

	* prior to commencement take bloods for APTT, INR, FBE, LFT's

full IV heparin Rx where increased risk of bleeding

	* eg. as adjunct to thrombolysis, the elderly, anti-platelet medications, post-op.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 12 Aug 2023 12:53:37 +0000</pubDate>
        </item>
        <item>
            <title>hepatic encephalopathy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hepatic_encephalopathy</link>
            <description>hepatic encephalopathy

see also:

	* gastroenterology
	* hepatitis
	* cirrhosis
	* ascites
	* assessment of hepatic function
	* prescribing drugs in patients with liver impairment
	* AFTB lectures - acute liver failure

factors that contribute to encephalopathy:

	* elevated levels of gut derived substances due to portosystemic shunting:
		* ammonia
		* false neurotransmitters (eg. octopamine)
		* changes in sensitivity of brain to inhibitory neurotransmitters (eg. GABA)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Aug 2018 07:41:10 +0000</pubDate>
        </item>
        <item>
            <title>assessment of hepatic function</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hepatic_function</link>
            <description>assessment of hepatic function

see also:

	* cirrhosis
	* prescribing drugs in patients with liver impairment
	* liver diseases
	* liver function tests (LFTs)

evaluating hepatic function

	* unfortunately, there is no single test that measures liver function.

index of suspicion of impaired function from clinical history

	* history of ethanol (alcohol and alcohol withdrawal) and illicit substance use</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 20 Nov 2023 12:59:34 +0000</pubDate>
        </item>
        <item>
            <title>hepatitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hepatitis</link>
            <description>hepatitis

see also:

	* gastroenterology
	* infectious diseases
	* liver function tests (LFTs)
	* jaundice (icterus)
	* liver diseases
	* cirrhosis
	* hepatic encephalopathy
	* assessment of hepatic function
	* prescribing drugs in patients with liver impairment
	* ethanol (alcohol and alcohol withdrawal)
	* viruses
		* hepatitis A
		* hepatitis B virus
		* hepatitis C virus

	* hepatocellular carcinoma

introduction

causes of hepatitis

	* ethanol (alcohol and alcohol withdrawal)
	* steatohep…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 Nov 2023 13:08:42 +0000</pubDate>
        </item>
        <item>
            <title>hepatomegaly</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hepatomegaly</link>
            <description>hepatomegaly

see also:

	* hepatosplenomegaly
	* splenomegaly
	* lymphadenopathy
	* liver diseases

introduction

	* patients with hepatomegaly or splenomegaly should be advised to avoid all contact sports as there is a risk of fatal organ rupture
	* rupture risk is higher in older patients as the capsule thins with age</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 Nov 2023 13:10:32 +0000</pubDate>
        </item>
        <item>
            <title>hepatosplenomegaly</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hepatosplenomegaly</link>
            <description>hepatosplenomegaly

see also:

	* hepatomegaly
	* splenomegaly
	* lymphadenopathy

introduction

	* craniocaudal measurement of 11-13 cm is frequently used as the upper limit of normal splenic size on imaging studies
	* 2-5% of the population have a palpable spleen
	* patients with hepatomegaly or splenomegaly should be advised to avoid all contact sports as there is a risk of fatal organ rupture</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 19 Oct 2024 11:27:38 +0000</pubDate>
        </item>
        <item>
            <title>herbicides</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=herbicides</link>
            <description>herbicides

see also toxicology

Glyphosate (Roundup, Zero):

introduction:

	* glyphosate is the most widely used general purpose herbicide in the world &amp; is a common household product
	* retail sale volumes exceed the volume of the next 6 leading herbicides combined</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Aug 2011 11:19:37 +0000</pubDate>
        </item>
        <item>
            <title>herniae</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hernias</link>
            <description>herniae

see also:

	* groin herniae
	* hernia_hiatus

introduction

	* abdominal herniae excluding groin or inguinal herniae:
		* ventral
			* incisional hernia
				* develop in 10-15% of sites of surgical incision in the abdominal wall as a result of failure of the fascial layers to close post-operatively</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Apr 2018 08:53:37 +0000</pubDate>
        </item>
        <item>
            <title>groin herniae</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hernia_inguinal</link>
            <description>groin herniae

see also:

	* herniae
	* groin pain
	* hip pain
	* undescended testes (cryptorchidism)
	* JSLS 2006: Hernias as a Cause of Chronic Pelvic Pain in Women

	* at Western Health, all adult patients presenting with inguinal herniae problems should be referred to surgical registrar to ensure timely surgical Mx and prevention of complicated disease

introduction</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Apr 2018 08:53:52 +0000</pubDate>
        </item>
        <item>
            <title>hepatitis E viruses (HEV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hev</link>
            <description>hepatitis E viruses (HEV)

see also:

	* hepatitis
	* &lt;https://wwwnc.cdc.gov/travel/yellowbook/2024/infections-diseases/hepatitis-e&gt;
	* &lt;https://www.who.int/news-room/fact-sheets/detail/hepatitis-e&gt;

	* HEV infection is a notifiable disease in  Victoria
		*  The disease is not endemic in Australia, and the majority of cases reported to date have occurred in travellers
		*  In Victoria in 2010, 11 cases were notified.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Jul 2025 23:27:24 +0000</pubDate>
        </item>
        <item>
            <title>heart failure with preserved EF (HFpEF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hfpef</link>
            <description>heart failure with preserved EF (HFpEF)

see also:

	* congestive cardiac failure

introduction

	* patients with heart failure who have LVEF &gt; 49%
		*  see heart failure with reduced ejection fraction (HFrEF) for Mx of those with LVEF &lt; 50%

	* HFpEF prevalence is increasing and now accounts for ~50% of patients with heart failure in Australia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 04:10:36 +0000</pubDate>
        </item>
        <item>
            <title>heart failure with reduced ejection fraction (HFrEF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hfref</link>
            <description>heart failure with reduced ejection fraction (HFrEF)

see also:

	* cardiology
	* cor pulmonale
	* acute pulmonary oedema (APO)
	* Mx of the wheezy elderly patient - acute pulmonary oedema versus asthma
	* AFTB lectures - APO
	* heart failure with preserved EF (HFpEF)
	* congestive cardiac failure
	* NB. age &gt; 65 with primary Dx of CCF are admitted to cardio-geriatric unit at Western Hospital if present to Western Health

Introduction

	* the following applies to patients with LVEF &lt; 41%</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 04:07:43 +0000</pubDate>
        </item>
        <item>
            <title>hiatus hernia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hiatus_hernia</link>
            <description>hiatus hernia

see also:

	* gastro-oesophageal reflux
	* SAGES US guidelines for Mx of hiatus hernia

introduction

	* hiatus hernia is when a portion of the stomach passes up through the diaphragmatic oesophageal hiatus
	* there are 4 types:
		* type I: sliding (95%) - where the lower oesophageal sphincter slides above the diaphragmatic oesophageal hiatus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 17 Oct 2016 08:55:42 +0000</pubDate>
        </item>
        <item>
            <title>hidradenitis suppurativa</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hidradenitis_suppurativa</link>
            <description>hidradenitis suppurativa

see also:

	* skin_abcess
	* perianal abscess

introduction

	* a chronic follicular occlusive disease that affects the intertriginous axillary, groin, perianal, perineal, and inframammary skin

staging

	* stage I: abscess formation without sinus tracts or scarring</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 06 Apr 2014 12:40:11 +0000</pubDate>
        </item>
        <item>
            <title>high pressure fluid spray / hydraulic injury</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=highpressure_injury</link>
            <description>high pressure fluid spray / hydraulic injury

see also:

	* plastic surgery

Introduction

	* high pressure fluids can cause initially innocuous injury but devastating delayed injuries

Epidemiology

	* most common in laborers in industry using high pressure sprays or hydraulics such as paint, automotive grease, solvents and diesel oil</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 21 Jan 2025 12:23:46 +0000</pubDate>
        </item>
        <item>
            <title>avascular necrosis hip / femoral head</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hip_avn</link>
            <description>avascular necrosis hip / femoral head

see also:

	* hip pain

introduction

	* avascular necrosis of the femoral head is responsible for some 12% of hip arthroplasties
	* incidence tends to be bimodal:
		* as Perthe's disease in pre-pubescent children
		* in adults under age 50 years, especially men aged 30-50.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 09 Oct 2013 04:06:06 +0000</pubDate>
        </item>
        <item>
            <title>labral tear hip joint</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hip_labral_tear</link>
            <description>labral tear hip joint

see also:

	* hip pain
	* A comprehensive review of hip labral tears. Curr Rev Musculoskelet Med. Jun 2009; 2(2): 105–117

introduction

	* tear of the labrum of the acetabulum is said to account for 20-50% of “idiopathic” hip pain where there is no obvious cause
	* diagnosis is often delayed by 2 years as the labrum is not well demonstrated on US, XRay, CT or MRI scans, although a MRA scan does have better sensitivity for detecting these tears.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 24 Oct 2014 03:08:18 +0000</pubDate>
        </item>
        <item>
            <title>hip pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hip_pain</link>
            <description>hip pain

see also:

	* knee pain
	* flank pain
	* back pain
	* groin pain
	* the limping child
	* rheumatology
	* RCH guidline - the child with hip pain or irritable hip
	* AAFP DDx of hip pain
	* J Fam Pract. 2003 August;52(8):607-617: an algorithmic approach to Dx of hip pain

differential diagnoses of groin/hip/thigh pain

paediatric

	* irritable hip / viral synovitis (very common)
	* septic arthritis hip (uncommon)
	* Perthe's disease (aged 3-9 years, uncommon)
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Jan 2025 10:21:52 +0000</pubDate>
        </item>
        <item>
            <title>histamine physiology, receptors and antihistamines</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=histamine</link>
            <description>histamine physiology, receptors and antihistamines

see also:

	* autacoids
	* allergy and hypersensitivity reactions
	* anaphylaxis
	* antihistamines (H1)
	* allergic rhinitis
	* pharmacology main index

introduction

	* 1st detected (with ACh) in ergot extracts as stimulants of uterus, but later both proved to be contaminants of ergot due to bacteria;
	* 1st isolated from body 1927 in various tissues hence histamine;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 May 2012 07:08:29 +0000</pubDate>
        </item>
        <item>
            <title>histoplasmosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=histoplasmosis</link>
            <description>histoplasmosis

see also:

	* fungi
	* antifungal agents

introduction

	* histoplasmosis is a fungal infection caused by Histoplasma capsulatum which grows as a yeast at mammalian body temperatures
	* it is mainly found in soils of organic rich river valleys between latitudes between 45° north and 30° south, and is spread via droppings from birds and bats</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 25 Apr 2014 02:04:08 +0000</pubDate>
        </item>
        <item>
            <title>historic perspectives of medicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=history</link>
            <description>historic perspectives of medicine

history of medicine blogs

	* Wonders and marvels - medical history blog by Holly Tucker
	* Aus Med Industry's timeline of medicine in Australia

timelines of medical history in this wiki

	* timeline of events in the history of medicine
	* history of anaesthesia
	* angiotensin converting enzyme inhibitors (ACEIs)and related
	* anticoagulants
	* beta adrenergic blockers
	* calcium channel physiology and pharmacology
	* pulmonary embolism
	* ischaemic heart dise…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 16 Jan 2013 14:45:46 +0000</pubDate>
        </item>
        <item>
            <title>HIV / AIDS</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hiv</link>
            <description>HIV / AIDS

see also:

	* viruses
	* antiretroviral agents
	* AIDS

Pre-exposure prophylaxis for HIV infection (PrEP)

	* these medications are used to reduce the risk of getting HIV infection
	* see &lt;https://www.cdc.gov/hiv/risk/prep/index.html&gt;
	* examples include:
		*  emtricitabine and tenofovir disoproxil fumarate
		*  emtricitabine and tenofovir alafenamide</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 29 Jan 2024 06:32:30 +0000</pubDate>
        </item>
        <item>
            <title>HLA-B27</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hla-b27</link>
            <description>HLA-B27

see also:

	* immunology
	* genetics
	* ankylosing spondylitis (AS)
	* adaptive immunity

introduction

	* Human Leukocyte Antigen (HLA) B27 is a class I surface antigen encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6 and presents antigenic peptides (derived from self and non-self antigens) to T cells.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 Nov 2023 10:09:21 +0000</pubDate>
        </item>
        <item>
            <title>human metapneumovirus (HMPV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hmpv</link>
            <description>human metapneumovirus (HMPV)

see also:

	* viruses
	* coryza / the common cold / viral rhinopharyngitis / rhinitis

Introduction

	* a negative-sense single-stranded RNA virus of the family Pneumoviridae (which also includes human respiratory syncytial virus / human orthopneumovirus (HRSV))
	* 1st isolated in 2001 although appears to have been circulating at least 50yrs prior
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 26 Sep 2023 23:44:05 +0000</pubDate>
        </item>
        <item>
            <title>hypertrophic cardiomyopathy (HCM or HOCM)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hocm</link>
            <description>hypertrophic cardiomyopathy (HCM or HOCM)

see also:

	* cardiomyopathy

introduction

	* idiopathic hypertrophy of the myocardium resulting in left ventricular hypertrophy (LVH) which is usually assymetric involving the interventricular septum in 2/3rds of cases
	* 25% have obstructed outflow at rest, while 70% have obstructed outflow under certain conditions (</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 01 Sep 2017 11:39:22 +0000</pubDate>
        </item>
        <item>
            <title>homelessness / no fixed abode</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=homelessness</link>
            <description>homelessness / no fixed abode

see also:

	* social issues
	* poverty
	* addiction medicine (alcohol and other substance use)

Introduction

	* home ownership is increasingly out of reach for most people
		*  divorce is likely to mean loss of home ownership, especially if the couple had failed to pay off the loan and the mortgage is still a high proportion of home value</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Feb 2025 00:10:07 +0000</pubDate>
        </item>
        <item>
            <title>home oxygen</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=home_oxygen</link>
            <description>home oxygen

see also:

	* oxygen
	* medical gases
	* hypoxia
	* respiratory medicine
	* chronic obstructive pulmonary disease (COPD)

adult domiciliary oxygen therapy

indications

	* continuous oxygen (ideally &gt; 19hrs/day):
		* is indicated to improve longevity &amp; quality of life if either:
			* stable daytime PaO2 is &lt; 55 mmHg at rest
			*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Jul 2014 05:09:08 +0000</pubDate>
        </item>
        <item>
            <title>honey</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=honey</link>
            <description>honey

see also:

	* diets and healthy foods

Introduction

	* honey is primarily composed of fructose (33-43%), glucose (25-35%), sucrose (0.2-2%) and water (17-20%) but also contains other substances which can have anti-oxidant, antibacterial and anti-inflammatory actions such as:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 Jan 2025 22:44:27 +0000</pubDate>
        </item>
        <item>
            <title>hormones</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hormones</link>
            <description>hormones

see also:

	* autacoids
	* cytokines

introduction

	* hormones are substances secreted from cells which act on target cells via cell membrane receptors
	* they may be:
		* autocrine - act on the same cell which secreted it
		* paracrine - act on local cells</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Mar 2026 02:02:42 +0000</pubDate>
        </item>
        <item>
            <title>Horner's syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=horners</link>
            <description>Horner's syndrome

see also:

	* stroke (CVA)
	* neurology

clinical features

	* classic triad of:
		* miosis (constricted pupil)
		* partial ptosis
		* loss of hemifacial sweating (anhidrosis)

	* ie. everything gets less or smaller

aetiology

	* brainstem stroke (CVA)
		* lateral medullary syndrome (Wallenberg's):</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 Jan 2015 02:03:12 +0000</pubDate>
        </item>
        <item>
            <title>human papilloma virus (HPV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hpv</link>
            <description>human papilloma virus (HPV)

see also:

	* viruses
	* sexually transmitted infections (STDs/STIs)

Introduction:

	* over 150 types but 15 are high risk types for inducing neoplasia / cancer / tumours in humans (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 73, and 82), 3 as probable high-risk (26, 53, and 66) and 12 as low-risk (6, 11, 40, 42, 43, 44, 54, 61, 70, 72, 81, and CP6108).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 22 Oct 2024 02:51:19 +0000</pubDate>
        </item>
        <item>
            <title>oestrogen hormone replacement therapy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hrt</link>
            <description>oestrogen hormone replacement therapy

see also:

	* oestrogens

summary

	* Recently, two major epidemiological studies found that hormone replacement therapy (HRT) in postmenopausal women increased the risk of breast cancer. One of the studies also found that HRT increased the risk of cardiovascular disease and thrombosis. As a consequence, women were advised to cease this therapy.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 22 Mar 2009 09:57:28 +0000</pubDate>
        </item>
        <item>
            <title>Henoch-Schonlein purpura (HSP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hsp</link>
            <description>Henoch-Schonlein purpura (HSP)

	* RCH guideline - HSP

	* The use of prednisolone has NOT been shown to make clinically important improvements in the rate of long-term renal complications.  
	* It HAS been shown to reduce the duration of abdominal and joint pain and may reduce the risk of abdominal complications.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Oct 2013 06:16:16 +0000</pubDate>
        </item>
        <item>
            <title>Herpes simplex virus (HSV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hsv</link>
            <description>Herpes simplex virus (HSV)

see also:

	*  sore throat and mouth in children
	*  antiviral agents
	*  viruses
	*  sexually transmitted infections (STDs/STIs)

Introduction

	* along with varicella-zoster virus, is a member of the neurotropic alpha group of the viral family herpetoviridae
	* class 1, enveloped double-stranded DNA virus which replicates via their own DNA polymerase but use host RNA polymerase to build mRNA</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Mar 2026 11:34:15 +0000</pubDate>
        </item>
        <item>
            <title>haemolytic uraemic syndrome  (HUS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hus</link>
            <description>haemolytic uraemic syndrome  (HUS)

see also:

	* thrombotic thrombocytopenic purpura (TTP)

Introduction

	* 1st defined as a syndrome in 1955
	* causes a similar clinical condition to thrombotic thrombocytopenic purpura (TTP) but with:
		*  being more common in children
		*  less neurologic abnormalities
		*  more renal impairments</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 09 Sep 2023 06:43:46 +0000</pubDate>
        </item>
        <item>
            <title>hydralazine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hydralazine</link>
            <description>hydralazine

see also:

	* vasodilators
	* antihypertensives

introduction

	* rapidly acting antihypertensive agent thought to directly act on peripheral arterioles primarily
	* increases renal and cerebral blood flow, increases plasma renin activity and causes sodium and water retention</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Oct 2013 07:29:03 +0000</pubDate>
        </item>
        <item>
            <title>hydrocephalus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hydrocephalus</link>
            <description>hydrocephalus

see also:

	* normal pressure hydrocephalus
	* The patient with a V-P shunt (VPS)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 25 May 2020 01:43:05 +0000</pubDate>
        </item>
        <item>
            <title>normal pressure hydrocephalus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hydrocephalus_np</link>
            <description>normal pressure hydrocephalus

see also:

	* hydrocephalus
	* weakness of the lower limb(s) / weak in the knees
	* The patient with a V-P shunt (VPS)

Introduction

	* normal pressure hydrocephalus can occur at any age but most commonly occurs in the elderly when it may present as dementia with disturbed gait (usually wide-based) and urinary incontinence
	* although it may follow an intracranial pathology such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 25 May 2020 01:43:17 +0000</pubDate>
        </item>
        <item>
            <title>hydroxychloroquine (Plaquenil)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hydroxychloroquine</link>
            <description>hydroxychloroquine (Plaquenil)

see also:

	* malaria
	* acute hydroxychloroquine or chloroquine overdose / toxicity (Plaquenil)

Introduction

	* hydroxychloroquine is an oral quinine type anti-malarial agent for prophylaxis and Rx of chloroquine-sensitive malaria cases
	* it also has uses in Rx of rheumatoid arthritis, systemic lupus erythematosus (SLE), Q fever and porphyria cutanea tarda
	* may have a role in Rx of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 26 Mar 2020 00:58:53 +0000</pubDate>
        </item>
        <item>
            <title>hydroxyurea</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hydroxyurea</link>
            <description>hydroxyurea

see also:

	* cytotoxic agents
	* polycythaemia rubra vera

Introduction

	* hydroxurea is an oral anti-metabolite medication used to Rx certain bone marrow disorders such as myeloproliferative diseases (polycythaemia rubra vera, essential thrombocytosis), sickle cell disease (SCD), CML (but now replaced by imatinib), systemic mastocytosis with associated hematological neoplasm(SM-AHN), and as a 2nd line agent in</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Jul 2025 02:14:14 +0000</pubDate>
        </item>
        <item>
            <title>hyperaldosteronism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperaldosteronism</link>
            <description>hyperaldosteronism

see also:

	* aldosterone antagonists
	* hypoaldosteronism
	* aldosterone
	* hypertension
	* endocrinology
	* physiology main index

Introduction

	* hyperaldosteronism is due to excessive aldosterone secretion from the adrenals and causes hypertension with hypokalaemia and metabolic alkalosis
	* it is characterized by a high serum level of aldosterone and a low serum renin level if primary and a high serum renin level is secondary</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Jun 2023 10:05:52 +0000</pubDate>
        </item>
        <item>
            <title>hyperalgesia - increased sensitivity to painful stimuli</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperalgesia</link>
            <description>hyperalgesia - increased sensitivity to painful stimuli

see also:

	* allodynia - painful touch when there should not be pain
	* neurology

Introduction

	* hyperalgesia is an increased sensitivity to painful stimuli 
	* allodynia - painful touch when there should not be pain is pain felt with non-painful stimuli
		*  affects 15-50% of people with neuropathic pain</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 22 Sep 2024 06:22:49 +0000</pubDate>
        </item>
        <item>
            <title>hypercalcaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypercalcaemia</link>
            <description>hypercalcaemia

see also calcium

Aetiology:

	* primary hyperparathyroidism
	* hypercalcaemia of malignancy - bone metastases / SCC lung / Ca kidney / multiple myeloma / lymphoma
	* sarcoidosis/vitamin D intoxication/milk-alkali synd./immobilisation
	* thyrotoxicosis/thiazides/familial hypocalciuric hypercalcaemia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 22 May 2018 01:15:18 +0000</pubDate>
        </item>
        <item>
            <title>hypercalcaemia of malignancy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypercalcaemia_malignancy</link>
            <description>hypercalcaemia of malignancy

see also hypercalcaemia; calcium

common oncologic causes:

	* multiple myeloma
	* breast carcinoma
	* squamous cell carcinoma lung
	* lymphoma
	* renal cell carcinoma

summary:

	* most common metabolic emergency in Oncology
	* symptoms if rapid rise or very high levels &gt; 3.0 mmol/l</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 23 Aug 2009 03:50:25 +0000</pubDate>
        </item>
        <item>
            <title>hyperemesis gravidarum</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperemesis_gravidarum</link>
            <description>hyperemesis gravidarum

see also:

	*  gynaecology; 
	*  Obstetrics; 
	*  pregnancy; 
	*  anti-emetics
	*  The Womens Hospital melbourne (RWH) Patient info sheet
	*  The Womens Hospital melbourne (RWH) clinical guideline on nausea and vomiting in pregnancy
	*  &lt;https://www.safercare.vic.gov.au/best-practice-improvement/clinical-guidance/maternity/nausea-and-vomiting&gt;

Introduction

	* nausea and vomiting effect up to 85% of pregnant women
		* usually mild and self-limiting, frequently resolving …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Jul 2025 00:51:34 +0000</pubDate>
        </item>
        <item>
            <title>DDx of hyperglycaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperglycaemia</link>
            <description>DDx of hyperglycaemia

see also:

	* diabetes mellitus
	* diabetic ketoacidosis (DKA)
	* hyperosmolar hyperglycaemic state (HSS or HONK)

introduction

	* blood glucose levels are normally kept within strict limits to prevent hypoglycaemia or dehydration from osmotic diuresis resulting from high levels of glucose in the blood with resultant glycosuria</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 21 May 2019 00:41:27 +0000</pubDate>
        </item>
        <item>
            <title>hyperkalaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperkalaemia</link>
            <description>hyperkalaemia

see also:

	* potassium physiology
	* hypokalaemia
	* rhabdomyolysis
	* UK Newcastle Mx flow chart (pdf)
	* Life in the fast lane - hyperkalaemia
	* medications which may cause or contribute to hyperkalaemia

introduction

	* hyperkalaemia is a potentially life-threatening emergency, but first one should ensure that the lab result is not a spuriously high result from post-venesection haemolysis of the blood specimen - if there is no ECG evidence, and no obvious reason for it, chec…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 12 Feb 2023 02:11:58 +0000</pubDate>
        </item>
        <item>
            <title>hyperkalemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperkalemia</link>
            <description>see hyperkalaemia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Feb 2009 03:25:13 +0000</pubDate>
        </item>
        <item>
            <title>hyperkeratosis / thickened skin / ichthyosis / lichenification</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperkeratosis</link>
            <description>hyperkeratosis / thickened skin / ichthyosis / lichenification

see also:

	* dermatology

Introduction

	* hyperkeratosis is excessive keratin buildup specifically in the outermost skin layer (stratum corneum), often from friction, pressure, or inflammation, forming rough, scaly patches like calluses</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2026 05:42:56 +0000</pubDate>
        </item>
        <item>
            <title>hyperlipidaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperlipidaemia</link>
            <description>hyperlipidaemia

see also:

	* cardiology; 
	* atherosclerosis - risk factors and molecular genetics
	* acute severe hypertriglyceridaemia (SHTG)
	* xanthelasma

Introduction

	* Hypercholesterolaemia is a major risk factor along with smoking, hypertension and diabetes for developing atherosclerosis and primary prevention.
	* Coronary heart disease is almost entirely due to atherosclerosis in the coronary arteries. 
	* atherosclerosis in the carotid arteries also plays a major role in</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 09 Aug 2024 00:49:25 +0000</pubDate>
        </item>
        <item>
            <title>hypermagnesaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypermagnesaemia</link>
            <description>hypermagnesaemia

see also:

	* magnesium
	* hypomagnesaemia

introduction

	* high plasma magnesium levels is rare as the kidney is very efficient at excreting high levels
	* it may be iatrogenic during iv magnesium sulphate infusions
	* elevated levels of magnesium appear to have a</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 Oct 2024 07:16:14 +0000</pubDate>
        </item>
        <item>
            <title>joint hypermobility disorders and syndromes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypermobility</link>
            <description>joint hypermobility disorders and syndromes

see also:

	* collagen disorders

Introduction

	* people with joint hypermobility (JHM) have a higher ratio of collagen III to collagen I (28-46% cw normal of 18-21%)
	* these people have a much higher degree of flexibility than normal but in general, cannot develop as much strength without very careful and rigorous training</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Mar 2023 20:34:24 +0000</pubDate>
        </item>
        <item>
            <title>hypernatraemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypernatraemia</link>
            <description>hypernatraemia

see also:

	* sodium physiology
	* dehydration
	* RCH guideline - hypernatraemia

introduction

	* hypernatraemia may be life threatening if severe, of if sodium level rapidly rises or rapidly falls

aetiology

reduced water intake

	* elderly patients with reduced thirst or ability to drink</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:17:30 +0000</pubDate>
        </item>
        <item>
            <title>dietary oxalates and hyperoxaluria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperoxaluria</link>
            <description>dietary oxalates and hyperoxaluria

see also:

	* urolithiasis / renal stones / renal calculi
	* Qld health patient information for renal stones including dietary advice (pdf)

Introduction

	* calcium oxalate stones account for 75-80% of urolithiasis / renal stones / renal calculi

Physiology

	* excessive amounts of oxalates in the urine (“hyperoxaluria”) is a significant risk factor in the formation of calcium oxalate kidney stones as urinary calcium concentrations are typically 10 times high…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2025 06:41:22 +0000</pubDate>
        </item>
        <item>
            <title>hyperparathyroidism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperparathyroidism</link>
            <description>hyperparathyroidism

see also:

	* parathyroid hormone (PTH)

Introduction

Primary hyperparathyroidism due to functional tumours causes

	* hypercalcaemia, hypophosphataemia, osteitis cystica, Ca stones kidneys;
		* Rx options include:
			* excision of tumour
			* cinacalcet
				* decreases PTH secretion</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 13 Apr 2025 10:35:51 +0000</pubDate>
        </item>
        <item>
            <title>hypertension</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypertension</link>
            <description>hypertension

	* RCH guideline - hypertension in children
	* antihypertensives

Introduction

	* it is important that BP be measured correctly:
		*  cuff should be at the level of the heart
		*  cuff should be the correct size for the patient
		*  arm should be resting on a desk - arm resting on the lap or unsupported gives BP readings 4-9mmHg higher</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 02:40:34 +0000</pubDate>
        </item>
        <item>
            <title>sudden transient surges in BP</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypertension_surge</link>
            <description>sudden transient surges in BP

see also:

	* hypertension

Introduction

	* for most patients with hypertension, BP is chronically elevated but some people with or without pre-existing hypertension may develop a sudden transient surge in their BP, mostly this is driven by the sympathetic system in response to severe pain, distress or anxiety and will usually settle when these are addressed, but there are some more serious albeit less common causes to consider and in these situations, the surge m…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Jun 2025 13:23:22 +0000</pubDate>
        </item>
        <item>
            <title>hyperthermia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperthermia</link>
            <description>hyperthermia

see also:

	* hypothermia

Introduction

	* a raised body core temperature may be due to a number of causes:
		*  normal physiology in pregnancy and menstrual cycle
		*  fever - the febrile response to infections
		*  heat illness and heat stroke
		*  in addition it may occur in response to medications such as:
			*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 07:33:46 +0000</pubDate>
        </item>
        <item>
            <title>hyperthyroidism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperthyroidism</link>
            <description>hyperthyroidism

see also:

	* thyroid physiology and hormones
	* hypothyroidism
	* Mx of a low TSH
	* Mx of high TSH
	* thyroid storm
	* Graves disease
	* thyroiditis

introduction

	* untreated hyperthyroidism may lead to:
		* loss of weight (but may cause paradoxic weight gain if it also causes congestive cardiac failure)
		* osteoporosis
		* atrial fibrillation
		* ophthalmopathy
			* an inflammatory eye disease that develops in the orbit in association with autoimmune thyroid disorders, par…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Oct 2021 07:17:54 +0000</pubDate>
        </item>
        <item>
            <title>acute severe hypertriglyceridaemia (SHTG)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypertriglyceridaemia_severe</link>
            <description>acute severe hypertriglyceridaemia (SHTG)

see also:

	* hyperlipidaemia
	* &lt;https://www.uwhealth.org/cckm/cpg/cardiovascular/related/Very-severe-hypertriglyceidemia---Adult---Inpatient-Emergency-Dept--181115.pdf&gt;

Introduction

	* acute severe and very severe hypertriglyceridemia causes cause chylomicronemia syndrome and is the 3rd most common cause of pancreatitis and should be suspected when obvious lipaemia is present on venipuncture blood specimens</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 29 Apr 2020 05:19:28 +0000</pubDate>
        </item>
        <item>
            <title>hyperuricaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyperuricaemia</link>
            <description>hyperuricaemia

see also:

	* uric acid
	* gout
	* uricosuric agents
	* oncology

Introduction

	* whilst low serum urate levels are associated with lower muscle mass, chronic illness and thus is associated with higher morbidity, high uric acid (urate) levels (hyperuricaemia) is associated with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Feb 2026 04:52:15 +0000</pubDate>
        </item>
        <item>
            <title>hypoalbuminaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypoalbuminaemia</link>
            <description>hypoalbuminaemia

see also:

	* nephrotic syndrome

Introduction

	* hypoalbuminaemia is often a marker of general illness and is associated with higher morbidity and mortality rates
	* albumin is a negative acute phase reactant in that serum levels FALL during acute inflammatory responses</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:49:59 +0000</pubDate>
        </item>
        <item>
            <title>hypoaldosteronism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypoaldosteronism</link>
            <description>hypoaldosteronism

see also:

	* aldosterone
	* aldosterone antagonists (mineralocorticoid receptor antagonists (MRAs) )
	* type IV renal tubular acidosis
	* wikipedia

introduction

clinical features

	* hyperkalaemia - often called type IV renal tubular acidosis even though metabolic acidosis is not a significant feature
	* urinary sodium wasting =&gt; volume depletion and hypotension

aetiology

hyporeninaemic hypoaldosteronism</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 18 Jan 2010 03:37:45 +0000</pubDate>
        </item>
        <item>
            <title>hypocalcaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypocalcaemia</link>
            <description>hypocalcaemia

see also calcium

aetiology:

	* if plasma phosphate high:
		* if plasma PTH low:
			* hypoparathyroidism - idiopathic/post-surgical

		* if plasma PTH high:
			* chronic renal disease (secondary hyperPTH)
			* pseudohypoparathyroidism


	* plasma phosphate normal or low:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Dec 2013 03:48:04 +0000</pubDate>
        </item>
        <item>
            <title>hypoglycaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypoglycaemia</link>
            <description>hypoglycaemia

see also:

	* diabetes_mellitus
	* hypoglycaemia in the non-diabetic patient
	* neonatal hypoglycaemia
	* RCH guideline - hypoglycaemia in children
	* RCH: oral hypoglycemic poisoning in children
	* Western Health P&amp;P - Mx of hypoglycaemia in adult diabetics (doc - WH Intranet only)

Introduction

	* in diabetic patients, hypoglycaemia is usually defined as blood glucose concentration less than 3.5 mmol/L  

Aetiology

	* diabetic patients on hypoglycaemic agents
		*  supplemental</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 09 Jul 2025 07:10:07 +0000</pubDate>
        </item>
        <item>
            <title>neonatal hypoglycaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypoglycaemia_neonatal</link>
            <description>neonatal hypoglycaemia

see also:

	* diabetes_mellitus
	* hypoglycaemia in the non-diabetic patient
	* hypoglycaemia
	* RCH guideline - hypoglycaemia in neonates

neonatal hypoglycaemia and resultant hypoglycaemic encephalopathy

	*  there are indications that even moderate neonatal hypoglycemia may be associated with structural brain abnormalities, impaired neurodevelopment, impaired executive function and visual motor function and poor school performances</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 22 May 2021 04:15:17 +0000</pubDate>
        </item>
        <item>
            <title>hypoglycaemia in the non-diabetic patient</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypoglycaemia_nondiabetic</link>
            <description>hypoglycaemia in the non-diabetic patient

see also:

	* hypoglycaemia
	* RCH guideline - hypoglycaemia in children

Introduction

	* hypoglycaemia in patients who are not taking oral hypoglycaemics or insulin is an uncommon presentation to ED
	* Whipple's triad:
		* documentation of low blood sugar
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:48:12 +0000</pubDate>
        </item>
        <item>
            <title>oral hypoglycaemic agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypoglycaemics</link>
            <description>oral hypoglycaemic agents

see also:

	* insulin
	* metformin
	* hypoglycaemia
	* diabetes mellitus

introduction

	* although for many years sulfonylureas were the first drugs to be used in new cases of type 2 diabetes (NIDDM), in the 1990s it was discovered that obese patients might benefit more from metformin.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 03 Sep 2025 10:47:43 +0000</pubDate>
        </item>
        <item>
            <title>hypokalaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypokalaemia</link>
            <description>hypokalaemia

see also:

	* potassium physiology
	* Life in the fast lane - Mx of hypokalaemia
	* Western Health procedure: Potassium chloride infusion

	* 1g KCl = ~13mmol K+
	* all intravenous potassium chloride should be prescribed in millimols
	* potassium chloride should not be administered at a rate greater than 10mmol/hour in adults on general wards
	* the maximum peripheral concentration of potassium chloride solution is 10mmol/100ml</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:11:34 +0000</pubDate>
        </item>
        <item>
            <title>hypomagnesaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypomagnesaemia</link>
            <description>hypomagnesaemia

see also:

	* magnesium
	* hypermagnesaemia
	* hypocalcaemia

introduction

	* magnesium is an important cation and often forgotten but low plasma levels may cause clinical effects, particularly severely low levels
	* unlike calcium, it is not under significant hormonal control and mobilisation of reserves from bone takes weeks</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:17:58 +0000</pubDate>
        </item>
        <item>
            <title>hyponatraemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyponatraemia</link>
            <description>hyponatraemia

see also:

	* sodium physiology
	* Mx of hyponatraemia
	* dehydration
	* cardiac failure
	* diabetes insipidus
	* hypernatraemia

introduction

	* hyponatremia is a serum sodium &lt; 135 mmol/L
	* most cases are caused by excessive water intake (oral or iv) and subsequent retention of water, particularly at risk are those with impaired ability to suppress ADH secretion, or if they have primary polydipsia which overwhelms the renal ability to excrete water (max. amount normal people c…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:17:18 +0000</pubDate>
        </item>
        <item>
            <title>Mx of hyponatraemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hyponatraemia_mx</link>
            <description>Mx of hyponatraemia

see also:

	* aetiology of hyponatraemia
	* sodium physiology
	* dehydration
	* for children see: RCH guideline - hyponatraemia in children

Mx of the patient with hyponatraemia

	* hyponatraemia must NOT be corrected rapidly as there is a significant risk of permanent brain injury
		* DO NOT give 0.9% saline or dextrose solutions in the ED for these patients</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Aug 2018 12:34:55 +0000</pubDate>
        </item>
        <item>
            <title>hypoparathyroidism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypoparathyroidism</link>
            <description>hypoparathyroidism

see also:

	* parathyroid hormone (PTH)

Introduction

	* hypoparathyroidism is usually due to excision of parathyroid glands and causes slowly developing hypocalcaemia over days/wks leading to tetany

Aetiology

	* surgical
		*  post-thyroidectomy with incidental removal of parathyroid glands or their blood supply</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Aug 2018 03:39:40 +0000</pubDate>
        </item>
        <item>
            <title>hypophosphataemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypophosphataemia</link>
            <description>hypophosphataemia

see also:

	* phosphate

Introduction

	* hypophosphatemia is usually asymptomatic even if severe, however, levels below 0.32mmol/L may cause symptoms such as seizures, muscle weakness, and even coma

Aetiology

transient intracellular shifts

	* acute respiratory alkalosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:18:26 +0000</pubDate>
        </item>
        <item>
            <title>hypotension</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypotension</link>
            <description>hypotension

see the shocked hypotensive patient</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 May 2014 06:35:01 +0000</pubDate>
        </item>
        <item>
            <title>hypothermia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypothermia</link>
            <description>hypothermia

see also:

	* frostbite
	* &lt;http://lifeinthefastlane.com/ccc/hypothermia/&gt;
	* hyperthermia

Introduction

	* many animals are able to enter a hypothermic physiologic state of torpor or hibernation at times of starvation and this appears to be activated at least in mice, by avMLPA neurons in the hypothalamus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 11 Jun 2024 12:07:02 +0000</pubDate>
        </item>
        <item>
            <title>hypothyroidism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypothyroidism</link>
            <description>hypothyroidism

see also:

	* thyroid physiology and hormones
	* Mx of high TSH

Introduction

	* hypothyroidism is a common chronic condition with an incidence of 3.5/1000 women and 0.6/1000 men.
	* subclinical hypothyroidism is detected in 4–8% of the general population and in up to 15–18% of women aged more than 60 years. 4–18% of patients will progress to overt hypothyroidism each year.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 31 Mar 2020 22:59:07 +0000</pubDate>
        </item>
        <item>
            <title>hypovolaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypovolaemia</link>
            <description>hypovolaemia

see:

	* the shocked hypotensive patient
	* dehydration</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Dec 2015 05:23:52 +0000</pubDate>
        </item>
        <item>
            <title>hypoxia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=hypoxia</link>
            <description>hypoxia

see also:

	* oxygen
	* arterial and venous blood gases (ABGs/VBGs)
	* home oxygen
	* respiratory medicine


oxygen content in blood
introduction

	* hypoxic hypoxia can be arbitrarily defined as arterial oxygen partial pressure of less than 80mmHg in room air 
	* an arterial PO2 &lt; 60mmHg indicates respiratory failure as, at oxygen levels below this, the Hb-oxygen dissociation curve is steep which means that the ability for Hb to carry much oxygen to the tissues is markedly diminished, …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Jul 2014 07:24:43 +0000</pubDate>
        </item>
        <item>
            <title>Historical perspectives on ACE inhibitors and related drugs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=h_aceis</link>
            <description>Historical perspectives on ACE inhibitors and related drugs

see historic perspectives of medicine, ACE inhibitors, pharmacology main index

Timeline:

	* Human ACE is a large protein with 1278 AA residues that cleaves dipeptide units from substrates with diverse AA sequences, but preferred substrates have only one free carboxyl group in the carboxyl-terminal AA, &amp; proline must not be the penultimate AA:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2008 01:03:07 +0000</pubDate>
        </item>
        <item>
            <title>history of anaesthesia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=h_anaesthesia</link>
            <description>history of anaesthesia

see also:

	* historic perspectives of medicine
	* anaesthetics

a brief history of local anaesthesia

	* 1860: Niemann purifies cocaine, an alkaloid contained in the leaves of Erythroxylon coca, a shrub growing in the Andes.
	* 1880: Von Anrep observed the local anaesthetic effects of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Mar 2009 02:46:40 +0000</pubDate>
        </item>
        <item>
            <title>Historical perspective of anticoagulants</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=h_anticoagulants</link>
            <description>Historical perspective of anticoagulants

see also anticoagulants, historic perspectives of medicine, history of PE

Timeline

	* around 1900, in rural US, veterinarians were puzzled by the mysterious sweet clover disease that caused cattle to develop fatal spontaneous bleeding.
	* heparin was discovered in 1915 by Jay McLean, searching for a pure procoagulant in dog liver &amp; heart, but finding anticoagulants instead. McLean's insight &amp; perserverence in pursuing this strange lead resulted in the …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Oct 2008 11:02:02 +0000</pubDate>
        </item>
        <item>
            <title>Historic perspective of beta adrenergic blockers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=h_betablockers</link>
            <description>Historic perspective of beta adrenergic blockers

see beta blockers

Timeline:

	* adrenergic responses classified as “alpha” &amp; “beta” in 1948
	* in late 1950's it was proposed that blockade of beta actions may be of benefit in Rx of angina &amp; hypertension</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 14 Sep 2008 13:31:14 +0000</pubDate>
        </item>
        <item>
            <title>Historical perspective of calcium channel physiology and pharmacology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=h_calciumchannel</link>
            <description>Historical perspective of calcium channel physiology and pharmacology

see historic perspectives of medicine

Timeline:

	* It was reported in 1960 that verapamil, a putative coronary vasodilator, possessed -ve inotropic &amp; chronotropic effects not seen with nitrate vasodilators.
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2008 00:55:18 +0000</pubDate>
        </item>
        <item>
            <title>history of cardiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=h_cardiology</link>
            <description>history of cardiology

see also:

	* historic perspectives of medicine
	* a brief history of medicine in Melbourne and Victoria
	* timeline of events in the history of medicine
	* History of use of anti-arrhythmic agents

21st century

2020's

	* AI enabled research based on genome analysis, microbiomes, transciptomes, etc
	* ED bedside ultrasound becomes common place for POCUS echocardiography
	* mechanical circulatory support:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Mar 2026 04:58:20 +0000</pubDate>
        </item>
        <item>
            <title>Historical perspective on ischaemic heart disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=h_ihd</link>
            <description>Historical perspective on ischaemic heart disease

see also:

	* ischaemic heart disease (IHD)
	* historic perspectives on medical discoveries
	* epidemiology:
		*  Am Heart Assoc. prevalence of ischaemic heart disease and cardiac infarcts and cardiac arrest by age group, etc


Historical perspective:

	* angina pectoris clearly described in 18th century by Heberden
	* Einthoven 1st described the string galvanometer in 1901
	* Cohn introduced the</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 05 Nov 2017 09:25:31 +0000</pubDate>
        </item>
        <item>
            <title>timeline of events in the history of medicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=h_medicine</link>
            <description>timeline of events in the history of medicine

see also:

	* historic perspectives of medicine
	* a brief history of medicine in Melbourne and Victoria
	* history of cardiology

21st century

2020's

	* Covid-19 pandemic
	* AI enabled research based on genome analysis, microbiomes, transciptomes, etc
	* 1st neural implant in a paralysed patient allows patient to play chess using thought control in 2024</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Mar 2026 04:00:41 +0000</pubDate>
        </item>
        <item>
            <title>a brief history of medicine in Melbourne and Victoria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=h_medicine_vic</link>
            <description>a brief history of medicine in Melbourne and Victoria

see also:

	* timeline of events in the history of medicine
	* western_history
	* RMH history
	* RCH history
	* timeline of vaccination in Victoria

21st century

	* Feb 2026: new Footscray Hospital opens
	* May 2019: Joan Kirner Womens and Childrens Hospital (JKWCH) at Sunshine Hospital opens
	* 2018: Labour wins state elections and announces funding for the building of a new Footscray Hospital</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 01:43:45 +0000</pubDate>
        </item>
        <item>
            <title>Historical perspectives of pulmonary embolism and its Mx</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=h_pe</link>
            <description>Historical perspectives of pulmonary embolism and its Mx

see also historic perspectives of medicine, pulmonary embolism (PE), historical perspectives of anticoagulant Rx

Historical events:

	* 11th C: death due to “sudden breathless sleep” found to be due to thrombus in pulmonary vessels
	* 1846: classic triad of venostasis, hypercoagulability &amp; vessel wall inflammation causing DVT was worked out by von Virchow who also was the 1st to show that pulm. arterial thrombus 1st develops in deep vein…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Oct 2008 10:59:41 +0000</pubDate>
        </item>
        <item>
            <title>historical perspectives of psychiatry and mental health care</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=h_psychiatry</link>
            <description>historical perspectives of psychiatry and mental health care

see also:

	* psychiatry and mental health
	* historic perspectives of medicine

clinical aspects of psychiatric care

	* BC - Hippocrates 4 personality types - choleric, melancholic, sanguine, &amp; phlegmatic
	* 1792 French physician Philippe Pinel introduced humane treatment approaches to those suffering from mental disorders</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Feb 2022 12:43:24 +0000</pubDate>
        </item>
        <item>
            <title>inflammatory bowel disease (IBD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ibd</link>
            <description>inflammatory bowel disease (IBD)

see also:

	* RIF pain in the ED
	* arthritis - clinical patterns
	* general surgery
	* gastroenterology
	* Crohn's disease
	* ulcerative colitis

introduction

	* inflammatory bowel disease is the generic term for a range of “autoinflammatory” diseases including:
		*  Crohn's disease
		*  ulcerative colitis
		*  microscopic colitis:
			*  more common in older adults (50-70 years old) and women</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Jan 2026 02:57:14 +0000</pubDate>
        </item>
        <item>
            <title>irritable bowel syndrome (IBS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ibs</link>
            <description>irritable bowel syndrome (IBS)

see also:

	* dysautonomia syndromes
	* coeliac disease
	* the patient with acute abdominal pain in the ED
	* carbohydrates and sugars
	* the GIT microbiome

introduction

	* IBS is a functional bowel disorder characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause and is thus a diagnosis of exclusion.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 10 Jan 2026 19:39:01 +0000</pubDate>
        </item>
        <item>
            <title>intracerebral haemorrhage (ICH) in adults</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ich</link>
            <description>intracerebral haemorrhage (ICH) in adults

see also:

	* stroke (CVA)
	* subarachnoid haemorrhage (SAH)
	* intraventricular haemorrhage (IVH) in adults

introduction

	* ICH may be caused by penetrating and non-penetrating trauma to the head
	* sites of non-traumatic ICH:
		* basal ganglia in 40-50%
		* lobar regions in 20-50% (mainly in those aged &lt; 45 yrs in association with AVMs)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 20 Jan 2016 07:12:18 +0000</pubDate>
        </item>
        <item>
            <title>infectious diseases</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=id</link>
            <description>infectious diseases

see also:

	*  microbiology
	*  viruses
	*  clinically important bacteria
	*  fungi
	*  antibiotics
	*  antiviral agents
	* RCH antibiotic guidelines
	* Vic. DHS infectious diseases Blue Book
	* Vic. DHS infectious diseases school exclusion periods
	* Vic. DHS notification of notifiable infectious diseases
	* RCH specimen collection handbook
	* Australasian Society for Infectious Diseases (ASID) - guidelines, etc
	* Australian Biosecurity research centre (ABCRC) for emerging…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Dec 2023 00:45:48 +0000</pubDate>
        </item>
        <item>
            <title>idarucizumab (Praxbind)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=idarucizumab</link>
            <description>idarucizumab (Praxbind)

see also:

	* product information sheet (pdf)

introduction

	* idarucizumab is a humanised monoclonal antibody fragment (Fab) molecule derived from murine IgG1 isotype antibody molecule, marketed in Australia as Praxbind™ as a specific reversal agent for</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:56:23 +0000</pubDate>
        </item>
        <item>
            <title>If current blockers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=if_blocker</link>
            <description>If current blockers

see also:

	* congestive cardiac failure

introduction

	* If blockers are agents which specifically inhibit the If “funny current” in the sino-atrial node which is responsible for pacemaking
	* these agents may also cause transient visual disturbances via interaction with hyperpolarisation-activated currents (Ih) in the retina</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Dec 2013 05:49:59 +0000</pubDate>
        </item>
        <item>
            <title>immunoglobulins</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ig</link>
            <description>immunoglobulins

see also:

	* serum electrophoresis
	* immunology
	* adaptive immunity
	* intravenous immunoglobulin (IVIg)
	* allergy and hypersensitivity reactions

introduction

	* a group of “antibody” proteins which form the “humoral” immune system and are produced by B lymphocytes - see adaptive immunity

IgA

	* a type of immunoglobulin that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Nov 2023 12:10:56 +0000</pubDate>
        </item>
        <item>
            <title>IgA deficiency</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=igadeficiency</link>
            <description>IgA deficiency

see also:

	* immunodeficiency

introduction

	* IgA deficiency is a subset of humoral (B-cell) immunodeficiencies
	* low or absent serum IgA levels may be an isolated immunoglobulin deficiency such as selective IgA deficiency, or be also associated with deficiency of other immunoglobulins such as IgG and IgM as with common variable immunodeficiency (CVID)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 13 Jul 2019 17:10:03 +0000</pubDate>
        </item>
        <item>
            <title>insulin-like growth factors (IGFs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=igf</link>
            <description>insulin-like growth factors (IGFs)

see also:

	* endocrinology
	* insulin
	* growth hormone / somatotropin

Introduction

	* insulin-like peptides are ancient peptides which evolved in metazoans long before vertebrate evolution, however, the basal vertebrate tetrapoidization events of chromosomal duplication resulted in increased diversification of these peptides and the ancestral insulin-like gene diverged into insulin, IGF-1 and IGF-2, and several ILPs including relaxin and relaxin-like pepti…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 30 Mar 2023 22:17:38 +0000</pubDate>
        </item>
        <item>
            <title>ischaemic heart disease (IHD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ihd</link>
            <description>ischaemic heart disease (IHD)

see also:

	* cardiology
	* atherosclerosis and primary prevention
	* acute myocardial infarction
	* Mx of chest pain in the ED
	* acute coronary syndromes
	* EBM for interventions in acute coronary syndromes
	* historical perspectives and timelines on IHD including the major research trials

Epidemiology:

general points:

	* also referred to as coronary artery disease (CAD)
	* incidence of coronary events = rate of occurrence of totality of fatal &amp; non-fatal even…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Feb 2023 10:04:51 +0000</pubDate>
        </item>
        <item>
            <title>interleukin-1b (IL-1b)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=il-1b</link>
            <description>interleukin-1b (IL-1b)

see also:

	* fever - the febrile response to infections
	* interleukin-6 (IL-6)
	* cytokines
	* immunology

Introduction

	* an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.
	* this and the eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Jul 2022 10:11:23 +0000</pubDate>
        </item>
        <item>
            <title>interleukin-6 (IL-6)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=il-6</link>
            <description>interleukin-6 (IL-6)

see also:

	* immunology
	* inflammation
	* CRP - science and pathophysiology

Introduction

	* IL-6 is an important mediator of the acute phase immune response acting as an immediate warning and systemic activation mechanism and acts as a bridge between the innate and adaptive immune systems, activating both.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 Aug 2025 07:30:36 +0000</pubDate>
        </item>
        <item>
            <title>Immunisation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=immunisation</link>
            <description>Immunisation

see also infectious diseases

	* RCH immunisation guidelines
	* RCH guideline - opportunistic immunisation
	* Aust. Govt immunisation schedule
	* 10th edition of the Australian Immunisation Handbook 2013
	* tetanus
	* viruses
	* needlestick injury
	* hepatitis
	* meningitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 May 2013 02:18:12 +0000</pubDate>
        </item>
        <item>
            <title>the immunocompromised patient in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=immunocompromised</link>
            <description>the immunocompromised patient in the ED

see also:

	* immunodeficiency
	* immunosuppressants
	* oncology
	* sepsis / septicaemia

Introduction

	* the immunocompromised patient is a high risk patient presenting to ED
	* they are at high risk of severe sepsis / septicaemia, atypical presentations, and rapid progression of surgical emergencies such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Jun 2022 02:27:00 +0000</pubDate>
        </item>
        <item>
            <title>immunodeficiency</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=immunodeficiency</link>
            <description>immunodeficiency

see also:

	* immunology
	* &lt;http://www.worldallergy.org/professional/allergic_diseases_center/suspected_immune_deficiency/&gt;
	* the immunocompromised patient in the ED

primary immunodeficiencies

	* these are genetic conditions and there are over 100 known conditions
	* most present in childhood with abnormally frequent (recurrent) or unusual infections
	* transmission is often X-linked and thus males are affected more than females</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 04 Apr 2017 00:27:43 +0000</pubDate>
        </item>
        <item>
            <title>intravenous immunoglobulin (IVIg)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=immunoglobulin</link>
            <description>intravenous immunoglobulin (IVIg)

	* RCH guideline - iv immunoglobulin
	* immunoglobulins

introduction

	* as of Sept 26th, 2016, a clinician must be registered with the National Blood Authority's BloodSTAR online system in order to be able to order IVIg for a patient</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 28 Jul 2016 07:15:10 +0000</pubDate>
        </item>
        <item>
            <title>immunology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=immunology</link>
            <description>immunology

see also:

	* innate immunity
	* adaptive immunity
	* autoimmune disease
	* inflammation
	* anaphylaxis
	* allergy and hypersensitivity reactions
	* immunodeficiency
	* immunoglobulins
	* cytokines
	* autacoids
	* fever - the febrile response to infections
	* multiple myeloma
	* pentraxins:
		* CRP
		* pentraxin 3 (PTX3)

	* public hospital immunology outpatient clinics in Victoria
		* RMH, Alfred, Monash, Box Hill
		* NB. suspected autoimmune rheumatologic conditions can usually be …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 Feb 2024 06:15:38 +0000</pubDate>
        </item>
        <item>
            <title>immunosuppressants</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=immunosuppressants</link>
            <description>immunosuppressants

see also:

	* pharmacology main index
	* progressive multifocal leukoencephalopathy (PML)
	* immunodeficiency
	* the immunocompromised patient in the ED

classes of immunosuppressant medications

	* azathioprine
	* corticosteroids
	* cyclosporin
	* methotrexate
	* cytotoxic agents
	* immunosuppressive monoclonal antibodies (mAbs)
	* topical immune modifiers:
		* imiquimod - Rx of solar keratoses, BCC, etc

	* selective interleukin inhibitors:
		* canakinumab - IL-1beta inhibi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 22 Aug 2023 04:59:39 +0000</pubDate>
        </item>
        <item>
            <title>immunosuppressive monoclonal antibodies (mAbs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=immunosuppressant_mabs</link>
            <description>immunosuppressive monoclonal antibodies (mAbs)

see also:

	* immunosuppressants
	* innate immunity
	* adaptive immunity
	* chemotherapy for cancers

Introduction

	* immunosuppressive monoclonal antibodies are a subset of monoclonal antibodies which target specific proteins on the T-lymphocyte or B-lymphocyte surface to result in immune suppression</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 22 Aug 2023 05:00:01 +0000</pubDate>
        </item>
        <item>
            <title>inclusion body myositis (IBM)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=inclusion_body_myositis</link>
            <description>inclusion body myositis (IBM)

see also:

	* polymyositis (PM)
	* dermatomyositis

introduction

	* rare but increasingly prevalent (with the aging population) chronic inflammatory myopathy
	* slowly progressive weakness and wasting of both distal and proximal muscles, of both arms and legs, and unlike</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 27 Sep 2013 06:53:48 +0000</pubDate>
        </item>
        <item>
            <title>induction agents for anaesthesia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=induction_agents</link>
            <description>induction agents for anaesthesia

see also:

	* anaesthetics
	* rapid sequence induction (RSI) for emergency intubation
	* neuro-muscular blockers

iv induction agents

	* features:
		* lipid-solubility =&gt; rapid crossing of BBB =&gt; rapid plasma:brain equilibrium
		* short duration of action - redistribution to other tissues

	* general principles:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Mar 2009 05:27:10 +0000</pubDate>
        </item>
        <item>
            <title>prevention of infection in healthcare - standard precautions</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=infection_prevention</link>
            <description>prevention of infection in healthcare - standard precautions

see also:

	* hand hygiene for health workers
	* aseptic non-touch technique (ANTT)
	* infectious diseases

Principles

	* ALL body fluids may contain transmissible infectious agents 

Standard Precautions for Infection Prevention

	* Standard precautions are work practices that provide a first-line approach to infection prevention in the healthcare environment and apply to ALL patients regardless of infectious status.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Dec 2023 00:42:36 +0000</pubDate>
        </item>
        <item>
            <title>infertility</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=infertility</link>
            <description>infertility

see also:

	* gynaecology
	* follicle stimulating hormone (FSH)
	* luteinizing hormone (LH)

introduction

	* defined as the inability for a couple to concieve within 1 year of unprotected intercourse
	* 15% of couples meet this criterion
	* 35% of these are due to female factors alone, 30% due to male factors alone, 20% due to combined male and female factors, and 15% are unexplained</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Apr 2026 00:32:36 +0000</pubDate>
        </item>
        <item>
            <title>influenza</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=influenza</link>
            <description>influenza

see also:

	* viruses
	* oseltamivir (Tamiflu)
	* zanamivir (Relenza)
	* Western Health influenza pandemic information
	* Timeline of spread of H1N1 pandemic 2009
	* Vic. DHS Chief Medical Officer's influenza alerts
	* CDC website for latest updates on Swine influenza A (H1N1) infection outbreak
	* Aust. Govt responses to the potential pandemic phase
	* Victorian DHS influenza pandemic site
	* Australian flu pandemic site
	* WHO information on swine flu
	* UpToDate.com - Epidemiology,…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Feb 2026 08:35:56 +0000</pubDate>
        </item>
        <item>
            <title>Inhibin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=inhibin</link>
            <description>Inhibin

see also:

	* gynaecology
	* follicle stimulating hormone (FSH)
	* luteinizing hormone (LH)
	* activin

Introduction

	* hormone secreted by luteal cells &amp; also by Sertoli cells of testes.

Actions:

	* the main inhibitory feedback mechanism for pituitary follicle stimulating hormone (FSH) secretion in males and has a major role in regulation of follicle stimulating hormone (FSH) secretion in females</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 May 2024 03:16:56 +0000</pubDate>
        </item>
        <item>
            <title>innate immunity</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=innate_immunity</link>
            <description>innate immunity

see also:

	* immunology
	* adaptive immunity
	* cytokines

introduction

	* innate immunity is a term used to refer to all types of immunity excluding adaptive immunity (acquired / adaptive immunity relies upon immune cells such as T-cell and B-cell lymphocytes which produce antibodies and these immune systems arose late in evolution, appearing in vertebrates), and thus is relatively non-specific</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Mar 2026 21:36:28 +0000</pubDate>
        </item>
        <item>
            <title>inotropes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=inotropes</link>
            <description>inotropes

see also:

	* sympathomimetics

introduction

	* inotropes are drugs that increase the force and velocity of myocardial contraction resulting in increased contractility and stroke volume, and therefore cardiac output.
	* vasopressors increase vascular tone, resulting in raised mean arterial pressure (MAP), and systemic vascular resistance.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Apr 2012 11:16:59 +0000</pubDate>
        </item>
        <item>
            <title>INR</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=inr</link>
            <description>INR

see also:

	* anticoagulants
	* activated partial thromboplastin time (APTT)
	* Mx of excessive INR or bleeding on warfarin Rx

introduction

	* the International Normalised Ratio or INR test measures the overall activity of the extrinsic coagulation pathway.
	* performed by adding thromboplastin to an aliquot of the patient's plasma
	* length of time taken for the mixture to clot is called the prothrombin time.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 Sep 2009 05:03:14 +0000</pubDate>
        </item>
        <item>
            <title>insecticides</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=insecticides</link>
            <description>insecticides

see also: acetylcholinesterase inhibitor poisoning - organophosphate insecticides, etc, toxicology, pharmacology main index

Chlorinated hydrocarbon insecticides:

4 groups:

i) DDT &amp; its analogues:

	* DDT, methoxychlor, TDE

ii) benzene hexachlorides:

	* BHC, lindane

iii) cyclodienes:

	* aldrin, chlordane, diedrin, heptachlor

iv) toxaphenes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Aug 2011 11:19:57 +0000</pubDate>
        </item>
        <item>
            <title>insect bites and stings</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=insect_bites</link>
            <description>insect bites and stings

see also:

	* animal bites in Australia
	* ticks in Australia
	* centipede bites
	* bed bugs
	* human louse / lice
	* toxinology
	* anaphylaxis
	* illness following floods
	* &lt;https://www.austin.org.au/bites-and-stings/&gt;

introduction

	* biting and stinging insects of medical concern include:
		* Diptera - mosquitoes, flies and gnats
		* Hymenoptera - ants, bees and wasps
		* Phthiraptera - lice</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 13 Mar 2026 12:34:43 +0000</pubDate>
        </item>
        <item>
            <title>High Insulin-Dextrose - Euglycaemia Therapy (HIET)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=insulin-dextrose_-_euglycaemia</link>
            <description>High Insulin-Dextrose - Euglycaemia Therapy (HIET)

see also:

	* &lt;http://coreem.net/core/hiet/&gt;

Introduction

	*  novel treatment for calcium channel blocker OD, can be considered in beta-blocker OD
	*  considered if refractory to IV fluids, calcium and inotropic support
	*  insulin has inotropic effect on heart - may take 20-30minutes to start after high dose bolus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Aug 2017 12:54:03 +0000</pubDate>
        </item>
        <item>
            <title>insulin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=insulin</link>
            <description>insulin

see also:

	* diabetes mellitus
	* diabetic ketoacidosis (DKA)
	* hypoglycaemia
	* High Insulin-Dextrose - Euglycaemia Therapy (HIET)
	* insulin-like growth factors (IGFs)
	* ghrelin
	* Western Health Intranet - Insulin prescribing, administration, etc
	* insulin overdose - wikitox

introduction

	* insulin dosing should be considered in terms of:
		* basal dosing with a long acting agent
		* prandial dosing prior to meals with regular insulin
		* corrective dosing with rapid acting ins…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 20 Feb 2023 00:02:22 +0000</pubDate>
        </item>
        <item>
            <title>insulin resistance</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=insulin_resistance</link>
            <description>insulin resistance

see also:

	* obesity
	* diabetes mellitus
	* insulin-like growth factors (IGFs)

Introduction

	* insulin resistance is when cells in your muscles, fat, and liver don’t respond well to insulin and can’t easily take up glucose from blood.
	* as a result, your pancreas makes more insulin to help glucose enter your cells</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Jun 2023 23:08:29 +0000</pubDate>
        </item>
        <item>
            <title>interferons</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=interferons</link>
            <description>interferons

see also:

	* immunology
	* innate immunity
	* adaptive immunity
	* cytokines

Introduction

	* interferons are a group of immune system signalling proteins belonging to the group of cytokines, named as they “interfere” with viral replication and were first described in 1957
	* in general, type I and II interferons are responsible for regulating and activating the immune response, in particular to viral infections, while type III interferons have important roles in both viral and fu…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 19 Jul 2024 07:57:17 +0000</pubDate>
        </item>
        <item>
            <title>interscapular thoracic back pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=interscapular_pain</link>
            <description>interscapular thoracic back pain

see also:

	* orthopaedics in the ED
	* acute thoracic back pain in the adult
	* the painful shoulder
	* the adult patient with chest pain in the ED

Introduction

	* pain between the shoulder blades is a relatively common problem and may be either referred pain or due to local causes

Referred pain

	* many causes of anterior chest pain also radiate through to the scapular region</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Jan 2026 10:36:22 +0000</pubDate>
        </item>
        <item>
            <title>interstitial cystitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=interstitial_cystitis</link>
            <description>interstitial cystitis

see also:

	* urinary tract infections (UTIs) / cystitis

introduction

	* interstitial cystitis is the term given to chronic urinary frequency, urgency, and pelvic pain of unknown etiology but with evidence of cystitis on cystoscopy
	* patients may have sterile pyuria 
	* 90% are female, median age 40yrs but may occur in pre-pubertal children</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 02 Jan 2014 06:05:00 +0000</pubDate>
        </item>
        <item>
            <title>interstitial lung disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=interstitial_lung</link>
            <description>interstitial lung disease

see also:

	* respiratory medicine

introduction

	* a diverse group of parenchymal lung diseases which result in damage to the lung interstitium with varying patterns of inflammation and pulmonary fibrosis
	* it is important to distinguish between idiopathic pulmonary fibrosis and other idiopathic interstitial pneumonias with a primary inflammatory pathogenesis as there are major prognostic and therapeutic implications.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 03 Dec 2016 08:36:04 +0000</pubDate>
        </item>
        <item>
            <title>emergency intubation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=intubation</link>
            <description>emergency intubation

see also:

	* anaesthetics
	* rapid sequence induction (RSI) for emergency intubation
	* delayed sequence induction
	* induction agents for anaesthesia
	* neuro-muscular blockers
	* assisted ventilation
	* Mx of the newly intubated patient in ED - post-intubation
	* nasogastric tube insertion
	* Western Health's intubation video on Vimeo

Introduction

	* emergency intubation is endotracheal intubation outside of theatre environments
	* induction of anaesthesia and attempte…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:55:41 +0000</pubDate>
        </item>
        <item>
            <title>intussusception</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=intussusception</link>
            <description>intussusception

	* RCH guideline - intussusception</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 07 Jan 2011 05:24:40 +0000</pubDate>
        </item>
        <item>
            <title>ipratropium</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ipratropium</link>
            <description>ipratropium

see also:

	* asthma
	* paediatric asthma
	* anti-muscarinic anticholinergic agents

introduction

	* a quaternary ammonium anticholinergic agent which is minimally absorbed (&lt;1% of dose) when inhaled and thus has localised action to the respiratory system
	* use is mainly confined to asthma and chronic obstructive pulmonary disease (COPD)
	* paediatric doses via inhaler should ideally be delivered using a spacer.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2009 07:11:04 +0000</pubDate>
        </item>
        <item>
            <title>intravenous iron Rx</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=iron_infusion</link>
            <description>intravenous iron Rx

see also:

	* iron deficiency anaemia
	* intravenous iron Rx (ferric carboxymaltose) at Western Health
	* NPS.org.au: ferric carboxymatose
	* Nat. Blood Authority Australia March 2016: Iron product choice and dose calculation for adults (pdf)

general information

	* there are 3 forms of parenteral iron for use in Australia:
		* iron polymaltose (Ferrum H and Ferrosig)
			* immediate HS reactions are common with iron polymatose - one MUST first use a small test dose</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Sep 2019 07:10:07 +0000</pubDate>
        </item>
        <item>
            <title>intravenous iron Rx (ferric carboxymaltose) at Western Health</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=iron_infusion_wh</link>
            <description>intravenous iron Rx (ferric carboxymaltose) at Western Health

see also:

	* iron deficiency anaemia
	* intravenous iron Rx
	* Melbourne Haematology Patient information sheet
	* Nat. Blood Authority Australia March 2016: Iron product choice and dose calculation for adults (pdf)

Introduction

	* ideally, patients requiring an iron infusion should be referred to Western Health's MADU outpatient service at Sunshine Hospital and NOT the emergency department as it is NOT an emergent problem.
	* when…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:54:35 +0000</pubDate>
        </item>
        <item>
            <title>isoniazid</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=isoniazid</link>
            <description>isoniazid

see also:

	* isoniazid overdose
	* tuberculosis (TB)
	* antibiotics

introduction

	* isoniazid (INH) has bacteriostatic activity against Mycobacterium tuberculosis and is one of the first line chemotherapeutic agents used in treating tuberculosis (TB)
	* high doses may cause pyridoxine (vitamin B6) deficiency states
	* isoniazid overdose results in reduced CNS GABA and seizures and coma which requires high dose iv</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Apr 2014 03:57:46 +0000</pubDate>
        </item>
        <item>
            <title>isotretinoin (Roaccutane)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=isotretinoin</link>
            <description>isotretinoin (Roaccutane)

see also:

	* retinoids
	* dermatology

introduction

	* isotretinoin (13-cis-retinoic acid) is an oral retinoid that has dramatically changed the Rx of a number of conditions, particularly acne vulgaris
	* it regulates growth and differentiation of epithelial cells by inhibiting epithelial proliferation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Apr 2014 07:57:29 +0000</pubDate>
        </item>
        <item>
            <title>Idiopathic thrombocytopenic purpura (ITP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=itp</link>
            <description>Idiopathic thrombocytopenic purpura (ITP)

	* RCH guideline - ITP</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 23:07:22 +0000</pubDate>
        </item>
        <item>
            <title>intravenous drug users (IVDU) or injection drug use (IDU)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ivdu</link>
            <description>intravenous drug users (IVDU) or injection drug use (IDU)

see also:

	* drug dependency
	* opiate and opioid dependence
	* infective endocarditis (including SBE)

introduction

	* intravenous drug users are a high risk patient group
	* ED issues include:
		* drug seeking behaviour
		* overdose, particularly, opiates and opioids
		* drug toxicity reactions, particularly,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 May 2011 06:30:42 +0000</pubDate>
        </item>
        <item>
            <title>ivermectin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ivermectin</link>
            <description>ivermectin

see also:

	* parasites

Introduction

	* a revolutionary “wonder-drug” being the 1st endectoside which was developed in the late 1970's derived from avermectin which was discovered in soil with a Japanese organism that produced it.
	* it has played a major role in under-developed countries fighting</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Sep 2021 03:07:19 +0000</pubDate>
        </item>
        <item>
            <title>in-vitro fertilisation (IVF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ivf</link>
            <description>in-vitro fertilisation (IVF)

see also:

	* ovulation induction for IVF
	* Monash IVF clinic
	* Melbourne IVF clinic
	* IVF Australia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 29 Jan 2014 01:11:59 +0000</pubDate>
        </item>
        <item>
            <title>intravenous (iv) fluids</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ivfluids</link>
            <description>intravenous (iv) fluids

see also:

	* dehydration
	* diabetic ketoacidosis (DKA)
	* &lt;http://emcrit.org/pulmcrit/crystalloid/&gt;

introduction

	* ideally a iv crystalloid would be close to physiologic and minimise incompatibilities with blood transfusions and other medications, these means:
		* no calcium
		* an osmolarity close to blood of 285mOsm/L</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Jul 2016 07:43:38 +0000</pubDate>
        </item>
        <item>
            <title>home &quot;backyard&quot; intra-uterine fertilisation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ivf_home</link>
            <description>home &quot;backyard&quot; intra-uterine fertilisation

see also:

	* gynaecology

introduction

	* occasionally a couple may present to ED with severe uterine pain after attempting intra-uterine fertilisation (IUF) at home.
	* they may have watched how the IVF professionals do it and after failed professional attempts decide to try it themselves using syringe and catheter which the spouse inserts into the cervix to inject semen.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Dec 2011 01:46:45 +0000</pubDate>
        </item>
        <item>
            <title>intraventricular haemorrhage (IVH) in adults</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ivh_adult</link>
            <description>intraventricular haemorrhage (IVH) in adults

see also:

	* stroke (CVA)
	* subarachnoid haemorrhage (SAH)
	* intracerebral haemorrhage (ICH) in adults

introduction

	* non-traumatic bleeding into the intracranial ventricles in adults is generally the result of either:
		* subarachnoid haemorrhage (SAH)
		* extension of intracerebral haemorrhage (usually in the thalamic ganglionic region) which is generally caused by:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 20 Jan 2016 07:10:13 +0000</pubDate>
        </item>
        <item>
            <title>Janus kinase - STAT signalling</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=jak</link>
            <description>Janus kinase - STAT signalling

see also:

	* myelofibrosis
	* myeloproliferative disorders
	* polycythaemia rubra vera
	* Janus kinase inhibitors
	* for more detail:
		*  2017: The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells


Introduction

	* Type I and II cytokine receptors are a conserved family of transmembrane proteins including the receptors for interleukins, interferons, erythropoietin, thrombopoietin, growth hormone, leptin and colony stimulating …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Aug 2025 04:30:10 +0000</pubDate>
        </item>
        <item>
            <title>JAK inhibitors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=jakinhibitors</link>
            <description>JAK inhibitors

see also:

	* Janus kinase - STAT signalling

Introduction

	* the JAK-family of cytokine receptors consists of four members: JAK1, JAK2, JAK3 and TYK2 that have different association patterns to receptors and are part of the Signal Transducer and Activation of Transcription (JAK-STAT) pathway</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 Jan 2026 09:46:33 +0000</pubDate>
        </item>
        <item>
            <title>jaundice (icterus)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=jaundice</link>
            <description>jaundice (icterus)

see also:

	* ascending cholangitis is a life threatening condition which requires immediate Rx and is suggested by presence of fever, RUQ pain and jaundice (Charcot's triad)
	* hepatitis
	* cirrhosis
	* liver diseases
	* assessment of hepatic function
	* neonatal jaundice

a diagnostic approach to the adult patient with obstructive pattern of abnormal LFT's</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 08 Feb 2025 06:13:37 +0000</pubDate>
        </item>
        <item>
            <title>Japanese encephalitis virus (JEV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=jev</link>
            <description>Japanese encephalitis virus (JEV)

see also:

	* WHO fact sheet
	* malaria
	* dengue fever
	* viruses
	* Murray Valley encephalitis (MVE)
	* &lt;https://www.health.vic.gov.au/infectious-diseases/japanese-encephalitis-virus&gt;

	* in 2026, the Victorian Govt advisary now has been updated to recommend recreational campers who go to northern half of Victoria should consider getting the Japanese encephalitis vaccine</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Apr 2026 11:25:01 +0000</pubDate>
        </item>
        <item>
            <title>Janus kinase inhibitors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=jk_inhibitors</link>
            <description>Janus kinase inhibitors

see also:

	* myelofibrosis
	* myeloproliferative disorders
	* polycythaemia rubra vera
	* Janus kinase - STAT signalling

introduction

	* the Janus kinase family of enzymes are associated with cell surface cytokine receptors and are part of the Signal Transducer and Activation of Transcription (JAK-STAT) pathway
	* in 2005, an acquired mutation of the Janus kinase 2 gene (V617F mutation) was discovered in &gt;95% of patients with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 22 Aug 2024 15:06:01 +0000</pubDate>
        </item>
        <item>
            <title>the swollen joint and its diagnostic workup</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=joint_swelling</link>
            <description>the swollen joint and its diagnostic workup

see also:

	* osteomyelitis and septic arthritis
	* rheumatoid arthritis
	* rheumatology
	* arthritis - clinical patterns
	* assessment of joint function and arthritis severity
	* extra-articular clinical features of rheumatologic conditions
	* RCH guideline - the acutely swollen joint

diagnostic workup of the patient with non-traumatic joint pain

	* there are no good screening tests for rheumatic diseases, a thorough history and examination with a …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 26 Mar 2018 05:23:23 +0000</pubDate>
        </item>
        <item>
            <title>Kambo poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=kambo</link>
            <description>Kambo poisoning

see also:

	* toxinology

Introduction

	* Kambo is a purging ritual using topically applied poison scraped from the back of the Amazonian giant tree frog (Phyllomedusa bicolor, kambô or sapo) that induces severe vomiting and exponents use it to</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 May 2023 10:19:23 +0000</pubDate>
        </item>
        <item>
            <title>Kaposi's sarcoma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=kaposi_sarcoma</link>
            <description>Kaposi's sarcoma

see also:

	* neoplasia / cancer / tumours
	* HIV / AIDS
	* viruses

Introduction

	* 1st described by Moritz Kaposi in 1872
	* it became an AIDS defining illness in 1981
	* it is not a true sarcoma as it is a tumor arising from mesenchymal tissue 

Prevalence

	* mainly occurs in Western cultures in those who have immune deficiency such as:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 31 Aug 2020 10:41:19 +0000</pubDate>
        </item>
        <item>
            <title>Kawasaki disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=kawasaki</link>
            <description>Kawasaki disease

	* RCH guideline - Kawasaki disease

introduction

	* a necrotising vasculitis affecting children involving the medium sized arteries with a predilection for the coronary arteries

diagnostic criteria

	* fever persisting for at least five days, plus 4 of the following 5 features:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 30 Aug 2012 07:26:37 +0000</pubDate>
        </item>
        <item>
            <title>keratitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=keratitis</link>
            <description>keratitis

see also:

	* ophthalmology
	* welder flash burns - UV keratopathy (photo keratitis)

Introduction

	* keratitis is inflammation of the cornea and may be caused by a variety of mechanisms:
		*  Herpes simplex virus (HSV)
		*  welder flash burns - UV keratopathy (photo keratitis)
		*  bacterial - including Pseudomonas
			*  a major issue in the immunocompromised, diabetic or those wearing contact lenses</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 28 Sep 2025 23:54:38 +0000</pubDate>
        </item>
        <item>
            <title>ketamine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ketamine</link>
            <description>ketamine

see also:

	* induction agents
	* RCH guideline - ketamine use in the paediatric ED

introduction

	* ketamine is a unique anaesthetic agent in that rather than causing general depression of neuronal activity, it causes dissociative anaesthesia which generally maintains airway reflexes and is generally safer that other anaesthetic agents, although it has it's own adverse effect profile and its relatively long duration of action means it may not be as suitable for very brief procedural …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 22 Aug 2025 10:39:39 +0000</pubDate>
        </item>
        <item>
            <title>ketorolac</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ketorolac</link>
            <description>ketorolac

see also non-steroidal anti-inflammatory drugs (NSAIDs)

introduction:

	* Structurally &amp; pharmacologically related to tolmetin &amp; indomethacin, however, unlike these pyrolle acetic acid derivatives, it is a cyclic propionic derivative.
	* It is the most potent analgesic of the NSAID's &amp; can be used in adults instead of narcotics to avoid the associated dependence problems of the narcotics.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 31 May 2025 03:42:59 +0000</pubDate>
        </item>
        <item>
            <title>kisspeptin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=kisspeptin</link>
            <description>kisspeptin

see also:

	* androgens
	* oestrogens

Introduction

	* kisspeptin is an endogenous peptide hormone discovered in 1996 and receptors for it were discovered in 2000
	* within the hypothalamus, kisspeptin is released from kisspeptin neurons and acts on nearby GnRH neurons to have a central role in regulation of LH secretion</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 Jan 2017 06:59:44 +0000</pubDate>
        </item>
        <item>
            <title>dislocation of the knee joint</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=knee_dislocation</link>
            <description>dislocation of the knee joint

see also:

	* the acutely injured knee in ED
	* trauma

	* after 8 hours of ischaemia, most will require an above knee amputation!!!
	* urgent reduction is critical!
	* assume all patients have a vascular injury until proven otherwise

introduction

	* an</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 08 Feb 2014 22:28:49 +0000</pubDate>
        </item>
        <item>
            <title>knee pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=knee_pain</link>
            <description>knee pain

see also:

	* hip pain
	* groin pain
	* the limping child
	* rheumatology

differential diagnoses of knee pain

paediatric

	* referred pain from the hip - see hip pain
		* eg. slipped upper femoral epiphyses (aged 9-15yrs)

	* osteomyelitis
	* septic arthritis knee (uncommon)
	* knee trauma - fractures femur/patella/tibia/fibula, dislocation patella/</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Dec 2016 04:26:39 +0000</pubDate>
        </item>
        <item>
            <title>koilonychia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=koilonychia</link>
            <description>koilonychia

see also:

	* clinical signs

introduction

	* koilonychia is a term to denote a concave “spooning” of the nails
	* it is most commonly caused by severe iron deficiency anaemia which may also cause angular stomatitis, altered tongue papillae (eg. atrophic glossitis), diffuse hair thinning, and dry, dull hair with split ends.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 02 Oct 2012 08:51:37 +0000</pubDate>
        </item>
        <item>
            <title>kyphosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=kyphosis</link>
            <description>kyphosis

see also:

	* orthopaedics in the ED
	* scoliosis

Introduction

	* kyphosis is the excessive convex bowing of the thoracic spine causing a hunchback appearance
	* it can be graded in severity by the Cobb angle taken in sagittal view ( the greatest angle at a particular region of the vertebral column, when measured from the superior endplate of a superior vertebra to the inferior endplate of an inferior vertebra)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 25 Sep 2023 09:11:17 +0000</pubDate>
        </item>
        <item>
            <title>labetalol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=labetalol</link>
            <description>labetalol

see also beta blockers

Introduction:

	* Racemic mixture of 4 isomers (beta-block 5 x alpha1-block):
		* RR: beta-block 4 x racemic; alpha1-block 20% of racemic; intrinsic beta2 agonist
		* RS: almost devoid blocker effects;
		* SR: almost no beta-block; alpha1-block 5 x racemic;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 17 Jul 2017 07:09:47 +0000</pubDate>
        </item>
        <item>
            <title>labial abscess / Bartholins abscess</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=labial_abscess</link>
            <description>labial abscess / Bartholins abscess

see also:

	* skin abscesses
	* JAMA 2016 - epidemiology of female pubic grooming

introduction

	* labial abscesses belong to two distinct groups:
		* Bartholin abscess which is an infection of the Bartholin gland in the lower half of the labia
		* other labial abscesses which usually start as a folliculitis, often following pubic hair grooming, but may be due to spread of a virulent Staph. aureus infection from other parts of the body</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Jul 2016 04:05:42 +0000</pubDate>
        </item>
        <item>
            <title>labour</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=labour</link>
            <description>labour

see also:

	* Obstetrics
	* ED Mx of 1st stage of labour 
		* Mx of cord prolapse

	* ED Mx of 2nd stage of labour - emergency delivery 
		* Mx of shoulder dystocia in labour
		* ED Mx of emergency breech delivery

	* ED Mx of 3rd stage of labour - delivery of placenta 
	* fetal macrosomia
	* preterm labour / premature labour
	* WH policy - Observations of Labouring Women (docx) - intranet only

features of normal labour:

1st stage:

	* typically lasts 10hr in nulliparous &amp; 8hrs in mult…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2013 04:49:56 +0000</pubDate>
        </item>
        <item>
            <title>1st stage of obstetric labour</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=labour_1ststagemx</link>
            <description>1st stage of obstetric labour

see labour; Mx of cord prolapse; ED Mx of 2nd stage of labour - emergency delivery;

initial assessment of mother &amp; baby:

	* check antenatal &amp; prenatal record for:
		* complications
		* estimated gestation
		* Rh gp &amp; Abs
		* group B streptococcal culture on vaginal swab
			* =&gt; needs prophylactic IV penicillin during labour &amp; to neonate</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 02 Nov 2008 12:31:19 +0000</pubDate>
        </item>
        <item>
            <title>Emergency delivery - 2nd stage of labour</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=labour_2ndstagemx</link>
            <description>Emergency delivery - 2nd stage of labour

see also: labour; ED Mx of emergency breech delivery; Mx of shoulder dystocia in labour; Mx of cord prolapse; neonatal resuscitation

	* Youtube animation of cephalic delivery

cephalic delivery:

	* have mother grasp post. aspect of distal portion thighs with hips &amp; knees flexed
	* encourage mother to “bear down” during contractions by holding breath with chin on chest for count of 10, repeated 2 or more times during each contraction, with quick breath …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 18 Apr 2011 03:59:48 +0000</pubDate>
        </item>
        <item>
            <title>ED Mx of 3rd stage of labour</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=labour_3rdstagemx</link>
            <description>ED Mx of 3rd stage of labour

see also:

	* labour
	* post-partum haemorrhage (PPH)
	* post-partum / puerperial complications
	* WH policy - Management of the Third Stage of Labour (docx) - intranet only

	* if blood loss &gt; 500mL then Mx as per post-partum haemorrhage (PPH)

delivery of placenta:

	* if mother Rh negative then take cord blood to determine need for maternal Rh Anti-D

physiologic Mx for PPH low risk patients who have consented to the potential increased risk of PPH</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 01 Jun 2020 06:13:26 +0000</pubDate>
        </item>
        <item>
            <title>ED Mx of emergency breech delivery</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=labour_breech</link>
            <description>ED Mx of emergency breech delivery

see also labour

breech position:

	* 3-4% of all deliveries (7% of 32wk &amp; 25% of 28wk deliveries)
	* factors associated:
		* polyhydramnios, oligohydramnios, hydrocephalus, previous breech, pelvic tumours, uterine anomalies</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 01 Jun 2023 14:23:14 +0000</pubDate>
        </item>
        <item>
            <title>laceration repair - glue vs staples vs sutures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lacerations</link>
            <description>laceration repair - glue vs staples vs sutures

see also:

	* paediatric lacerations
	* tetanus prophylaxis
	* plastic surgery
	* the injured hand
	* other resources:
		*  Wound Management in the Emergency Department by Hartmut Gross (pdf)


staple repair

	* staples are useful where a cosmetic result is not critical and are particularly useful for scalp lacs where healing time and cosmetic outcomes are similar to suturing while being faster, cheaper and potentially avoiding painful LA injection…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 Jul 2018 06:24:22 +0000</pubDate>
        </item>
        <item>
            <title>paediatric lacerations</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lacerations_paed</link>
            <description>paediatric lacerations

see also:

	* tetanus prophylaxis
	* plastic surgery
	* the injured hand
	* laceration repair - glue vs staples vs sutures
	* RCH guideline - lacerations
	* RCH guideline - tetanus-prone wounds</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 Jul 2018 06:00:40 +0000</pubDate>
        </item>
        <item>
            <title>serum lactate and lactic acidosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lactate</link>
            <description>serum lactate and lactic acidosis

see also:

	* sepsis / septicaemia
	* &lt;https://emcrit.org/isepsis/isepsis-lactate-myths/&gt;

Introduction

	* the normal serum lactate range is up to 2 mmol/L (18 mg/dL)
	* raised serum lactate &gt; 4 mmol is often used as a marker for severe sepsis or localised ischaemia such as bowel or limb ischaemia and its use in at risk patients helps to detect occult severe sepsis or bowel ischaemia earlier</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Jan 2018 01:18:55 +0000</pubDate>
        </item>
        <item>
            <title>the lactating patient in ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lactating_pt</link>
            <description>the lactating patient in ED

see also:

	* milk and dairy products
	* post-partum / puerperial complications
	* Australian Therapeutic Guidelines including drugs in pregnancy for WH users
	* Australian Breastfeeding Association - breast and nipple care
	* Australian Breastfeeding Association - breast feeding main index 
	* Australian Prescriber 2011 - analgesics in pregnancy and breastfeeding

introduction

	* the patient who is breastfeeding raises several issues to be considered including choi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Feb 2026 10:14:14 +0000</pubDate>
        </item>
        <item>
            <title>Lactobacillales</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lactobacillales</link>
            <description>Lactobacillales

see also:

	* clinically important bacteria

Introduction

	* an order of acid-tolerant Gram positive bacilli bacteria
	* these bacteria, usually found in decomposing plants and milk products, produce lactic acid as the major metabolic end product of carbohydrate fermentation.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 03:32:17 +0000</pubDate>
        </item>
        <item>
            <title>lactose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lactose</link>
            <description>lactose

see also:

	* carbohydrates and sugars
	* serum lactate and lactic acidosis
	* lactose intolerance
	* lactulose

Introduction

	* lactose is a disaccharide sugar which in nature, is only found in mammalian milk (mammals evolved 201-227 million years ago and one of the features in which they differed from sauropsids / reptilia  was they had evolved to have milk producing breasts to feed their young)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 03 Jul 2019 05:30:50 +0000</pubDate>
        </item>
        <item>
            <title>lactose intolerance</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lactose_intolerance</link>
            <description>lactose intolerance

see also:

	* lactose
	* irritable bowel syndrome (IBS)

Introduction

	* lactose cannot be absorbed by the gut wall, absorption relies upon it being broken down into glucose and galactose which can be absorbed
	* mammals lose their ability to break down ingested lactose after weaning as unnecessary production of lactase in the duodenum has an energy cost and evolution generally avoids persistent unnecessary energy costs to the cell</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 03:07:54 +0000</pubDate>
        </item>
        <item>
            <title>lactulose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lactulose</link>
            <description>lactulose

see also:

	* lactose
	* constipation
	* laxatives

Introduction

	* lactulose is a sugar which is not absorbable from the gut and hence is used as a laxative for the treatment of constipation and hepatic encephalopathy (can be given rectally for ammonia reduction)
	* it is made from heating lactose
	* it is marketed as Duphalac or Actilax (3.3g lactulose per 5mL)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 03:29:42 +0000</pubDate>
        </item>
        <item>
            <title>reducing language barriers in clinical care</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=language_barriers</link>
            <description>reducing language barriers in clinical care

see also:

	* patient information sheets

smartphone real time language translation

	* be aware that these are not perfect, especially for medical terminology and you may end up getting lost in translation!
	* as of 2014:
		* &lt;http://www.gizmodo.com.au/2014/06/how-to-turn-your-mobile-device-into-a-universal-translator/&gt;


Word Lens</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Jun 2014 03:32:57 +0000</pubDate>
        </item>
        <item>
            <title>laxatives</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=laxatives</link>
            <description>laxatives

see also:

	* constipation

Introduction

	* see under Mx of constipation

oral stool softeners

	* docusate
		* 240mg (2 x 120mg tablets) daily
		* takes 1-3 days to work
		* can be used in pregnancy


oral bulking agents

	* useful if there is a dietary fibre deficiency</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 03:28:54 +0000</pubDate>
        </item>
        <item>
            <title>large bowel obstruction</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lbo</link>
            <description>large bowel obstruction

see also:

	* the patient with acute abdominal pain in the ED
	* small bowel obstruction

introduction

	* obstruction of the large bowel results in proximal dilatation (and potentially dilatation of small bowel) with inability to pass faeces or flatus.
	* excessive distension may result in perforation and</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 07 Jan 2011 05:42:45 +0000</pubDate>
        </item>
        <item>
            <title>lactic dehydrogenase (LDH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ldh</link>
            <description>lactic dehydrogenase (LDH)

see also:

	* haemolytic anaemia
	* haptoglobin (Hp)

Introduction

	* serum lactic dehydrogenase
	* tissue breakdown releases LDH, and therefore LDH can be measured as a surrogate for tissue breakdown such as occurs in haemolytic anaemia, rhabdomyolysis and tumour necrosis and is also raised in many other conditions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 May 2018 23:55:54 +0000</pubDate>
        </item>
        <item>
            <title>lead poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lead</link>
            <description>lead poisoning

see also:

	* toxicology
	* wikipedia

Introduction

	* children are most at risk as lead is absorbed at a faster rate compared to adults and their faster growth and development makes them more susceptible

History

	*  lead plumbing pipes were widely used in western cities from the late 1800s</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Jan 2026 04:45:32 +0000</pubDate>
        </item>
        <item>
            <title>Legionella (Legionaire's disease)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=legionella</link>
            <description>Legionella (Legionaire's disease)

see also:

	* clinically important bacteria
	* pneumonia

introduction

	* gram negative, aerobic clinically important bacteria 
	* Legionella pneumophila
		*  an aquatic organism mainly thriving in the cooling system of air conditioning towers at temperatures of 25-45°C, and is responsible for &gt;90% of cases of potentially fatal Legionellossis (Legionaire's disease) and the milder form, Pontiac fever.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Dec 2019 13:51:29 +0000</pubDate>
        </item>
        <item>
            <title>leishmaniasis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=leishmaniasis</link>
            <description>leishmaniasis

see also:

	* parasites
	* insect bites and stings
	* the febrile returned traveller

introduction

	* leishmaniasis is a disease caused by protozoan parasites that belong to the genus Leishmania and is transmitted by the bite of certain species of sand fly.
	* human infection is caused by about 21 of 30 species that infect mammals.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 29 Aug 2022 07:08:06 +0000</pubDate>
        </item>
        <item>
            <title>Lemiere's syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lemiere</link>
            <description>Lemiere's syndrome

see also:

	* sepsis / septicaemia
	* sore throats in adults

Introduction

	*  a rare syndrome caused by the anaerobe F. necrophorum secondary to oropharyngeal infections mainly in 18-35 yr olds
	*  infection extends from the pharynx into the parapharyngeal spaces of the neck and then causes septic thrombophlebitis of the internal jugular vein</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 09 Nov 2024 00:30:31 +0000</pubDate>
        </item>
        <item>
            <title>leptospirosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=leptospirosis</link>
            <description>leptospirosis

see also:

	* zoonoses
	* NSW Govt fact sheet

Introduction

	* Leptospirosis is caused by a cork-screw shaped bacteria of the genus Leptospira.
	* It is transmitted by the urine and semen of an infected animal and is contagious as long as the urine is still moist</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 31 Mar 2018 12:04:47 +0000</pubDate>
        </item>
        <item>
            <title>leukaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=leukaemia</link>
            <description>leukaemia

see also:

	* neoplasia / cancer / tumours
	* lymphoma
	* myeloproliferative disorders
	* wikipedia

Introduction

	* usually present by causing anaemia, bleeding from thrombocytopenia, or infections or mouth ulcers from impaired immunity from inadequate mature, functional white cells
	* chronic forms may be detected incidentally on blood films, or by finding</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Nov 2025 09:49:32 +0000</pubDate>
        </item>
        <item>
            <title>leukocytosis (high WCC)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=leukocytosis</link>
            <description>leukocytosis (high WCC)

Introduction

	* leukocytosis refers to a raised white cell count (WCC) in the peripheral blood and this may be an acute response to a high sympathomimetic system activating stress reaction (eg. vomiting, beta agonist use, corticosteroid use), and infection, pregnancy, or it may be chronic due to a myeloid bone marrow disorder such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Aug 2023 07:31:56 +0000</pubDate>
        </item>
        <item>
            <title>leukopenia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=leukopenia</link>
            <description>leukopenia

see also:

	* neutropenia
	* lymphopenia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 13 Jun 2024 01:17:13 +0000</pubDate>
        </item>
        <item>
            <title>levetiracetam (Keppra)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=levetiracetam</link>
            <description>levetiracetam (Keppra)

see also:

	* anticonvulsants
	* seizures

Introduction

	* levetiracetam is a newer anticonvulsant with similar efficacy as phenytoin for status epilepticus but without the iv line incompatibility issues
	* main mechanism involves binding to the synaptic vesicle protein 2A (SV2A), a key component of nerve cell vesicles, which modulates neurotransmitter release, potentially by inhibiting presynaptic calcium channels and reducing glutamate release, likely reducing excessiv…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jan 2026 03:51:00 +0000</pubDate>
        </item>
        <item>
            <title>liver function tests (LFTs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lfts</link>
            <description>liver function tests (LFTs)

see also:

	* assessment of hepatic function
	* liver diseases
	* cirrhosis
	* hepatomegaly
	* hepatitis

introduction

	* liver functions tests are commonly ordered as a screening test for patients with upper abdominal pain, jaundice (icterus), or for a variety of other presentations.
	* ALT and AST are the main markers of liver damage, although thse can also be raised in muscle damage conditions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Dec 2025 05:55:04 +0000</pubDate>
        </item>
        <item>
            <title>luteinizing hormone (LH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lh</link>
            <description>luteinizing hormone (LH)

see also:

	* follicle stimulating hormone (FSH)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 21 Mar 2026 00:07:09 +0000</pubDate>
        </item>
        <item>
            <title>human louse / lice</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lice</link>
            <description>human louse / lice

see also:

	* insect bites and stings
	* bed bugs

Introduction

	* the human louse has been a long standing pest for humans and can carry a range of pathogenic organisms

Evolution

	* Pediculus humanus capitis (head lice / nits)
		*  a common problem amongst school children aged 3-11yrs due to close play</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Feb 2026 10:20:15 +0000</pubDate>
        </item>
        <item>
            <title>lichen planus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lichen_planus</link>
            <description>lichen planus

see also:

	* dermatology

Introduction

	* a chronic skin and mucosal autoimmune T-cell mediated condition

Epidemiology

	* affects 1% of the population
	* mainly those aged 30-60yrs

Risk factors

	* genetic
	* may be precipitated by:
		*  stress</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2026 05:11:58 +0000</pubDate>
        </item>
        <item>
            <title>lignocaine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lignocaine</link>
            <description>lignocaine

see also:

	* local anaesthetic agents
	* anti-arrhythmic agents
	* ventricular tachycardia (VT)
	* ventricular fibrillation (VF)

history

	* Introduced 1948 &amp; still the most widely used LA

actions

LA Action:

	* As for cocaine but little euphoria/fever &amp; more prompt, longer-lasting, more intense &amp; more extensive anaesthesia than procaine;

VW class 1b anti-arrhythmic action:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Mar 2009 02:24:49 +0000</pubDate>
        </item>
        <item>
            <title>Paediatric limb fractures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=limb_fractures_paed</link>
            <description>Paediatric limb fractures

see also:

	* orthopaedics in the ED
	* Bier's block - iv regional anaesthesia for LAMPs
	* the injured hand
	* fractures of the metacarpal
	* fractures and dislocations of the fingers
	* RCH guidelines - limb fractures
	* RCH guideline - procedural pain management
	* RCH guideline - Bier's block
	* RCH guideline - Local Anaesthetic, Manipulation and Plaster (LAMP)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 03 Jul 2013 03:59:57 +0000</pubDate>
        </item>
        <item>
            <title>acute limb ischaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=limb_ischaemia</link>
            <description>acute limb ischaemia

see also:

	* peripheral vascular disease (PVD or PAD)
	* vascular surgery
	* West J Med. 2000 Jul; 173(1): 60–63. Chronic lower limb ischemia

introduction

	* acute limb ischaemia is a time critical condition which requires rapid recognition, assessment and management to save the limb and perhaps the patient's life.
	* it is not an uncommon cause of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 12 Apr 2023 05:51:50 +0000</pubDate>
        </item>
        <item>
            <title>the limping child</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=limp_paed</link>
            <description>the limping child

see also:

	* the child with hip pain - irritable hip vs septic arthritis
	* orthopaedics in the ED
	* arthritis - clinical patterns

all ages:

	* trauma:
		* fracture
		* occult growth plate trauma - esp. distal fibula
		* haemarthrosis - usually underlying intra-articular fracture
		* non-accidental injuries

	* foreign body:
		* esp. feet/knees eg. occult sewing needles, rose thorns (either may be intra-articular!!)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Sep 2009 11:37:29 +0000</pubDate>
        </item>
        <item>
            <title>links</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=links</link>
            <description>links

introduction

	* there are a multitude of links throughout this wiki and these can be found using the search field at top left.
	* this page is an effort to provide some collation of main link pages.

main link pages

	* welcome to the OzEMedicine Wiki
	* OzEMedicine blog main links page
	* medical blogs and podcasts
	* medical web portals, directories, news aggregators, etc
	* patient information sheets
	* Australian health care providers
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 Feb 2009 17:52:24 +0000</pubDate>
        </item>
        <item>
            <title>lipase</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lipase</link>
            <description>lipase

see also:

	* amylase

introduction

	* serum lipase levels are used primarily as an indicator for acute pancreatitis when it starts to rise 3-6hrs after onset and usually peaks around 24hrs from onset, but as there is significant reabsorption from the renal tubules, levels remain elevated for 8-14 days.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Mar 2025 22:43:56 +0000</pubDate>
        </item>
        <item>
            <title>lipoedema</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lipoedema</link>
            <description>lipoedema

see also:

	* obesity and weight management
	* the obese patient in the ED
	* connective tissue (CT) disorders
	* the patient with swollen leg(s)

Introduction

	* often confused with obesity or lymphedema / lymphoedema, lipoedema is a separate condition independent of diet, lifestyle but is a hereditary, connective tissue disorder which results in disproportionate excessive lipoedema fat on legs and sometimes upper arms</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 22 Mar 2023 22:43:16 +0000</pubDate>
        </item>
        <item>
            <title>Listeria monocytogenes / Listeriosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=listeria</link>
            <description>Listeria monocytogenes / Listeriosis

see also:

	* clinically important bacteria

Introduction

	* Listeria monocytogenes may cause potentially fatal sepsis or meningitis in at risk people such as neonates, pregnant women, elderly or the immunocompromised
	* it is found in soil and water and is spread as a food-borne infection from eating contaminated foods, particularly, fruit, vegetables, dairy products such as soft cheeses, or processed meats such as pate or cold cuts</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Sep 2018 04:06:11 +0000</pubDate>
        </item>
        <item>
            <title>lithium carbonate</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lithium</link>
            <description>lithium carbonate

see also:

	* bipolar disorder
	* Aust. Prescriber Feb 2013

introduction

	* although lithium was first discovered to be effective in mania in 1949, by the Melbourne psychiatrist John Cade, it is still the 'gold standard' therapy.
		* many patients are unable to tolerate lithium and it has limited effectiveness for the depressive phase of bipolar disorders.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Jan 2014 07:29:53 +0000</pubDate>
        </item>
        <item>
            <title>liver physiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=liver</link>
            <description>liver physiology

see also:

	* liver diseases
	* assessment of hepatic function
	* liver function tests (LFTs)
	* jaundice (icterus)
	* hepatomegaly
	* hepatosplenomegaly
	* steatohepatitis (fatty liver)
	* cirrhosis
	* prescribing drugs in patients with liver impairment
	* hepatic encephalopathy
	* hepatocellular carcinoma

Introduction

	* the adult liver normally weighs ~1.5kg
	* it has a dual blood supply, both vessels entering the liver via the porta hepatis hilum on the under surface of t…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 20 Nov 2023 12:44:26 +0000</pubDate>
        </item>
        <item>
            <title>liver diseases</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=liver_disease</link>
            <description>liver diseases

see also:

	* liver physiology
	* assessment of hepatic function
	* liver function tests (LFTs)
	* jaundice (icterus)
	* hepatomegaly
	* hepatosplenomegaly
	* liver lesions - hepatic abscesses, cysts and nodules
	* steatohepatitis (fatty liver)
	* cirrhosis
	* portal hypertension
	* prescribing drugs in patients with liver impairment
	* hepatic encephalopathy
	* hepatocellular carcinoma

Introduction

	* liver disease is a common presentation to the ED whether it be an acute hepa…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Jul 2024 04:30:27 +0000</pubDate>
        </item>
        <item>
            <title>liver lesions - hepatic abscesses, cysts and nodules</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=liver_lesions</link>
            <description>liver lesions - hepatic abscesses, cysts and nodules

see also:

	* liver diseases

Introduction

	* these lesions are often found unexpectedly on ultrasound scans or CT scans

hepatic cysts or abscesses

DDx

	* pyogenic hepatic abscesses
		*  more frequently located in the right than both or left liver lobes (60-70% vs. 25% and 15% cases, respectively)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 11 Jul 2024 05:45:18 +0000</pubDate>
        </item>
        <item>
            <title>loneliness</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=loneliness</link>
            <description>loneliness

see also:

	* psychiatry and mental health
	* antidepressants
	* suicide
	* Geriatric depression scale
	* stress
	* happiness
	* sadness
	* depression

Introduction

	* a study published Mar 2025 of 57,000 middle aged Australian women showed that those who reported persistently feeling lonely had a 3x rate of death over the 15 year study period compared to those without persistent loneliness</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 08 Apr 2025 00:32:26 +0000</pubDate>
        </item>
        <item>
            <title>longevity and immortality</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=longevity</link>
            <description>longevity and immortality

see also:

	* geriatrics
	* ageing
	* calculating 10yr atherosclerotic cardiovascular disease risk using pooled cohort equations (PCE)

Introduction

	* 21st century science empowered by AI-driven advances currently on average add 3 months of life to every 12 months you live, thus a healthy 60 yr old on this basis could live 5 years or so more than the average life span of around 85 years (although Covid-19 pandemic may have had a negative effect on the long term quali…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 06 May 2024 01:32:32 +0000</pubDate>
        </item>
        <item>
            <title>Ludwig's angina - floor of mouth infection</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ludwigs</link>
            <description>Ludwig's angina - floor of mouth infection

see also:

	* ears, nose and throat surgery (ENT)
	* sore throats in adults
	* acute dental pain / dental abscess
	* Lemiere's syndrome
	* Vincent's angina - fusospirochaetal infection of the pharynx and tonsils

Introduction

	* Ludwig's angina is a rapidly progressive, bilateral, gangrenous floor of the mouth cellulitis which can cause airway compromise as well as sepsis and is a medical emergency</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2024 05:32:26 +0000</pubDate>
        </item>
        <item>
            <title>lumbar disc prolapse</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lumbar_disc_prolapse</link>
            <description>lumbar disc prolapse

see also:

	* back pain in the ED
	* sciatica
	* cauda equina syndrome (CES)
	* high lumbar disc prolapse
	* cervical disc prolapse

introduction

	* the intervertebral disc / disk comprises the annulus fibrosus and the nucleus pulposus.
	* lumbar disc herniation occurs when the nucleus pulposus protrudes from the defective annulus fibrosus because of its degeneration and it's a common and important cause of low</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 07 Nov 2024 22:32:33 +0000</pubDate>
        </item>
        <item>
            <title>high lumbar disc prolapse</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lumbar_disc_prolapse_high</link>
            <description>high lumbar disc prolapse

see also:

	* back pain in the ED
	* sciatica
	* cauda equina syndrome (CES)
	* lumbar disc prolapse

Introduction

	* lumbar disc prolapse at the higher lumbar vertebral discs (L1-L3 level) account for a small minority of all lumbar disc prolapses, and as they generally affect the L2-3 nerve roots the most, and these supply the femoral nerve and not the sciatic nerve, the clinical features, and management are quite different from the usual</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 01 Nov 2021 02:26:49 +0000</pubDate>
        </item>
        <item>
            <title>lumbar puncture (LP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lumbar_puncture</link>
            <description>lumbar puncture (LP)

see also:

	* meningitis
	* subarachnoid haemorrhage (SAH)
	* interpretation of CSF findings
	* post LP headaches (PLPH)
	* Seupaul, R Perform an LP and analyze the results to dx bacterial meningitis. Emergency Physicians Monthly August 2008. 
	* RCH guideline - lumbar puncture (LP)
	* Emedicine.com - lumbar puncture
	* Youtube demo LP tutorial

introduction

	* most patients with suspected meningitis require the diagnosis to be confirmed by LP as confirmation will not only…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 26 Oct 2019 01:00:39 +0000</pubDate>
        </item>
        <item>
            <title>lung crepitations</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lung_crepitations</link>
            <description>lung crepitations

see also:

	* stridor
	* noisy breathing
	* wheeze

Introduction

	* lung or pulmonary crepitations are crackling noises heard mainly on ausculatation
	* they are traditionally described as either:
		*  coarse - usually due to sputum retention and generally clear on coughing</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Feb 2019 23:54:13 +0000</pubDate>
        </item>
        <item>
            <title>lung lesions</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lung_lesions</link>
            <description>lung lesions

see also:

	* lung cancer

Introduction

	* lung lesions are often found incidentally on CXRs or CT scans ordered by GPs or in the ED
	* TB and lung cancers are common and need to be excluded or followed up appropriately when suspicion arises
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 20 Nov 2023 06:47:29 +0000</pubDate>
        </item>
        <item>
            <title>lower urinary tract symptoms (LUTS) in men</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=luts</link>
            <description>lower urinary tract symptoms (LUTS) in men

see also:

	* urinary tract infections (UTIs) / cystitis
	* sexually transmitted infections (STDs/STIs)
	* benign prostatic hyperplasia (BPH)
	* European Assoc. Urology guidelines for LUTS

Introduction

	* lower urinary tract symptoms (LUTS) are common in men and more prevalent as they become older and can impair quality of life
	* they fall into three main categories:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2025 06:47:08 +0000</pubDate>
        </item>
        <item>
            <title>left ventricular failure (LVF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lvf</link>
            <description>left ventricular failure (LVF)

see also:

	* acute pulmonary oedema (APO)
	* congestive cardiac failure</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Dec 2015 04:14:15 +0000</pubDate>
        </item>
        <item>
            <title>Lyme disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lyme</link>
            <description>Lyme disease

see also:

	* zoonoses
	* ticks in Australia
	* louse-borne relapsing fever
	* tick-borne relapsing fever
	* &lt;http://medent.usyd.edu.au/fact/lyme%20disease.htm&gt;

Introduction

	* Lyme disease is a condition caused by the spirochete bacterium Borrelia burgdorferi  which is spread to humans by certain types of tick bites
	* given the diverse symptomatology, it's ability to imitate many other conditions, and the apparent sometimes chronic nature of the symptoms, the diagnosis has beco…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 27 Oct 2025 05:08:49 +0000</pubDate>
        </item>
        <item>
            <title>cervical lymphadenitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lymphadenitis_cervical</link>
            <description>cervical lymphadenitis

see also:

	* lymphadenopathy
	* RCH guideline - cervical lymphadenitis

Introduction

	* enlarged cervical lymph nodes are common and usually occur in response to an URTI or tonsillitis
	* they may also occur with other local infections including dental or cutaneous
	* occasionally they may form an abscess within the node which may require surgical drainage</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 05 Feb 2026 07:04:51 +0000</pubDate>
        </item>
        <item>
            <title>lymphadenopathy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lymphadenopathy</link>
            <description>lymphadenopathy

see also:

	* splenomegaly
	* cervical lymphadenitis

introduction

	* the body has approximately 600 lymph nodes, but only those in the submandibular, axillary or inguinal regions may normally be palpable in healthy people
	* in most patients, lymphadenopathy has a readily diagnosable infectious cause.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 15 Oct 2025 05:32:20 +0000</pubDate>
        </item>
        <item>
            <title>lymphocytosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lymphocytosis</link>
            <description>lymphocytosis

see also:

	* full blood examination (FBE)
	* neutrophilia
	* monocytosis
	* lymphopenia
	* lymphadenopathy

introduction

	* the finding of a raised WCC due to lymphocytosis rather than neutrophilia is generally a reassuring find which suggests viral infection rather than bacterial infections although it is a typical finding in</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 06 Sep 2024 06:58:16 +0000</pubDate>
        </item>
        <item>
            <title>lymphedema / lymphoedema</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lymphoedema</link>
            <description>lymphedema / lymphoedema

see also:

	* the patient with swollen leg(s)
	* lipoedema
	* obesity and weight management
	* the obese patient in the ED

Introduction

	* often confused with obesity or lipoedema

aetiology

primary

	* congenital lymphedema (Milroy disease) 
		* AD disorder;
		* accounts for 10-25% of primary cases
		* starts in 1st yr of life, usually painless, pitting oedema</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 22 Mar 2023 22:31:23 +0000</pubDate>
        </item>
        <item>
            <title>lymphoma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lymphoma</link>
            <description>lymphoma

see also:

	* neoplasia / cancer / tumours
	* EBV / glandular fever / infectious mononucleosis
	* NSW Cancer Institute eviQ cancer therapy EBM website 

introduction

	* lymphomas are the 6th most common type of cancer excluding non-melanoma skin cancers with 1 in 39 people developing a NH lymphoma and 1 in 414 people developing Hodgkin's lymphoma by age 85yrs
	* incidence is rising in Australia (doubled in past 20 yrs)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 12 Nov 2025 08:12:12 +0000</pubDate>
        </item>
        <item>
            <title>mantle cell lymphoma (MCL)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lymphoma_mantlecell</link>
            <description>mantle cell lymphoma (MCL)

see also:

	* lymphoma
	* Fact sheet (pdf)
	* LLS Fact sheet (pdf)
	* Int J Molecular Sciences 2019 review article (pdf)

Introduction

	* accounts for ~7% of non-Hodgkin lymphoma (NHL) cases
	* most patients are aged over 50yrs (men have 2-7x risk)
	* so-called because the tumour cells originally come from the “mantle zone” (the outer edge) of the lymph node</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 22 Aug 2025 09:52:19 +0000</pubDate>
        </item>
        <item>
            <title>lymphopenia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lymphopenia</link>
            <description>lymphopenia

see also:

	* full blood examination (FBE)
	* lymphocytosis
	* neutropenia

introduction

	* most commonly is due to viral infections but also occurs with many states which cause either:
		* neutrophilia
			* such as acute stress response (including exercise), corticosteroids, inflammation including bacterial infections,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 26 Oct 2019 00:03:08 +0000</pubDate>
        </item>
        <item>
            <title>lysozyme (LYZ)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=lysozyme</link>
            <description>lysozyme (LYZ)

see also:

	* the GIT microbiome
	* innate immunity
	* atherosclerosis and primary prevention

Introduction

	* lysozyme (LYZ) plays an important role in bacterial lysis, by hydrolyzing the glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine and destroying the peptidoglycan (PG)-rich cell walls of gram-positive bacteria</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 09 Jul 2025 00:50:17 +0000</pubDate>
        </item>
        <item>
            <title>macular degeneration</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=macdegen</link>
            <description>macular degeneration

see also:

	* the patient with acute blurred vision or visual loss / blindness
	* MD Foundation booklet
	* MD Foundation's free Amsler Grid for regular home testing of central visual loss

Introduction

	* MD is the main cause of legal blindness in Australia, accounting for over 50% of cases and affects 1 in 7 over the age of 50 yrs, of which 17% experience visual impairment, and some 15% of Australians over 80yrs of age have visual loss due to MD</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 21 Feb 2020 23:55:33 +0000</pubDate>
        </item>
        <item>
            <title>macrolide antibiotics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=macrolides</link>
            <description>macrolide antibiotics

see also:

	* antibiotics

introduction

	* bactericidal, binds to 23S rRNA on the 50S subunit, activity enhanced at high pH
		* active against most Gram +ves, Mycoplasma, Legionella, Chlamydia, Helicobacter
		* uses for the usual macrolides (eg. erythromycin, roxithromycin):</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Aug 2011 10:59:15 +0000</pubDate>
        </item>
        <item>
            <title>madarosis (loss of eyebrows)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=madarosis</link>
            <description>madarosis (loss of eyebrows)

see also:

	* dermatology

Introduction

	* madarosis is the term used for partial or full loss of eyebrow hairs

Aetiology

	* local causes
		*  trauma
		*  burns
		*  radiation therapy
		*  trichotillomania
		*  alopecia areata
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 08 Mar 2023 11:57:08 +0000</pubDate>
        </item>
        <item>
            <title>magnesium</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=magnesium</link>
            <description>magnesium

see also:

	* hypomagnesaemia
	* hypermagnesaemia
	* eclampsia

introduction

	* magnesium is the fourth most abundant mineral present in the human body. More than 600 enzymes require it as a co-factor and almost 200 require it to activate critical processes in the body.
	* Mg is the 2nd most abundant intracellular cation, playing major roles in:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 12 Mar 2025 22:54:09 +0000</pubDate>
        </item>
        <item>
            <title>microangiopathic hemolytic anemias (MAHAs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mahas</link>
            <description>microangiopathic hemolytic anemias (MAHAs)

see also:

	* thrombotic microangiopathy (TMA)

Introduction

	* microangiopathic hemolytic anemias (MAHAs) are caused by spontaneous aggregation of platelets and activation of coagulation in the small blood vessels creating a fibrin mesh on endothelial walls</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 08 Sep 2023 09:08:28 +0000</pubDate>
        </item>
        <item>
            <title>malabsorption</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=malabsorption</link>
            <description>malabsorption

see also:

	* diarrhoea
	* RCH guideline: failure to thrive in infants</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Dec 2017 00:33:17 +0000</pubDate>
        </item>
        <item>
            <title>malaria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=malaria</link>
            <description>malaria

see also:

	* travel medicine
	* the febrile returned traveller
	* transdermal detection of malaria in blood using laser to create nanobubbles in the RBC and then acoustic assessment of them bursting - low cost, battery powered devices may revolutionise diagnosis

	* prophylactic antimalarials do not eliminate the possibility of malaria and may extend the incubation period by many weeks, appropriate testing should always be done for a febrile traveller without obvious cause returning fr…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:50:54 +0000</pubDate>
        </item>
        <item>
            <title>malignant hyperthermia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=malignant_hyperthermia</link>
            <description>malignant hyperthermia

see also:

	* heat illness and heat stroke
	* fever - the febrile response to infections
	* hyperthermia
		* neuroleptic malignant syndrome (NMS)
		* serotonin syndrome
		* amphetamine overdose

	* wikipedia

Introduction

	* malignant hyperthermia (MH) is a type of severe reaction in susceptible people that occurs when given anaesthetic gases or suxamethonium
	* affects one in 5,000 to 50,000 cases where people are given anesthetic gases</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 07:29:14 +0000</pubDate>
        </item>
        <item>
            <title>monoamine oxidase inhibitors (MAOIs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=maois</link>
            <description>monoamine oxidase inhibitors (MAOIs)

see also:

	* antidepressants

Introduction

	* MAOIs were one of the early types of antidepressants but are now rarely used as there are safer alternatives for most people

	* the main risk is in the patient developing a potentially life threatening</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 07 Jun 2022 03:04:31 +0000</pubDate>
        </item>
        <item>
            <title>Marfan's syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=marfans</link>
            <description>Marfan's syndrome

see also:

	* connective tissue (CT) disorders
	* Ehlers-Danlos syndrome</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 02 Feb 2013 13:17:58 +0000</pubDate>
        </item>
        <item>
            <title>marijuana / cannabis / THC</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=marijuana</link>
            <description>marijuana / cannabis / THC

see also:

	* Addiction medicine - drug and alcohol - main index and links
	* drug dependency
	* cannabinoid hyperemesis
	* Wikipedia - marijuana
	* NSW Govt - facts and links on marijuana

Introduction:

	* recreational smoking of the products of the subtropical plant Cannabis sativa, mainly its dried resin (hashish - smoked in a pipe), oily extract from flowering tops (hash oil) , or the chopped flowering tops of the female plant (marijuana</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Oct 2025 04:42:51 +0000</pubDate>
        </item>
        <item>
            <title>marine stings in Australia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=marine_stings</link>
            <description>marine stings in Australia

see also:

	* animal bites in Australia
	* insect bites and stings

jellyfish

blue bottle or Portugese man'o'war (Physalia sp.)

	* small blue creatures with an air sac which allows them to float with the wind on the sea surface (although often they end up stranded on beaches in their thousands as a result), and up to 1m long tentacles which can cause a painful sting lasting around 2hrs and welts lasting 1-2 days, and rarely</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Mar 2017 05:48:35 +0000</pubDate>
        </item>
        <item>
            <title>massage guns</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=massage_guns</link>
            <description>massage guns

see also:

	* orthopaedics in the ED

Introduction

	* percussion massage muscle guns are commonly used by professional athletes and nonathletes worldwide for warm-up and physical recovery as well as by the general community to help with low back pain and other muscle pains</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Sep 2021 06:07:42 +0000</pubDate>
        </item>
        <item>
            <title>mastitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mastitis</link>
            <description>mastitis

see also:

	* gynaecology
	* The Womens Hospital Melbourne patient fact sheet - mastitis

introduction

	* mastitis is a common complication of lactation in the post partum period and is usually caused by Staphylococcus aureus.
	* see the above fact sheet for its prevention and early Mx.

ED Mx of established puerperal mastitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Jan 2012 23:27:49 +0000</pubDate>
        </item>
        <item>
            <title>mastocytosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mastocytosis</link>
            <description>mastocytosis

see also:

	* anaphylaxis

Introduction

	*  a rare disorder affecting both children and adults caused by the accumulation of functionally defective mast cells (“mastocytes”) and CD34+ mast cell precursors
	*  usually present as recurrent anaphylaxis or</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 19 Oct 2024 11:16:39 +0000</pubDate>
        </item>
        <item>
            <title>measles</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=measles</link>
            <description>measles

see also:

	* viruses
	* paediatric exanthems
	* acute rashes in adults

	* immediately isolate and mask all patients with possible measles:
			* born after 1966
			* high fevers with cough and either conjunctivitis or rash


introduction

	* also called rubeola
	* measles virus (MV), a negative-sense enveloped RNA virus, is a member of the Morbillivirus genus in the Paramyxoviridae family.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 11 Jul 2022 05:28:25 +0000</pubDate>
        </item>
        <item>
            <title>Meckel's diverticulum</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=meckels</link>
            <description>Meckel's diverticulum

see also:

	* diverticulitis
	* emedicine

introduction

	* congenital true diverticulum anomaly of the bowel due to remnant of the embryonic vitelline duct
	* may contain gastric mucosa
	* 4-25% develop complications with surgical lifetime risk of ~6%, mostly in the 1st 2 yrs of life</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Sep 2016 07:23:34 +0000</pubDate>
        </item>
        <item>
            <title>medical blogs and podcasts</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=medblogs</link>
            <description>medical blogs and podcasts

see also:

	* medical web portals, directories, news aggregators, etc
	* health informatics
	* LITFL database of EM blogs

	* hint: there are links to specific podcasts throughout this wiki - just search for podcasts in the search field to find them

Introduction

	*  many health organisations and professionals maintain their own</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 25 Nov 2014 00:18:44 +0000</pubDate>
        </item>
        <item>
            <title>mediastinitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mediastinitis</link>
            <description>mediastinitis

see also:

	* the adult patient with chest pain in the ED

Introduction

	* mediastinum is the extrapleural subdivision of the thorax located between the pleural cavities
	* non-suppurative mediastinitis is generally self-limiting reactive condition in association with pneumonia and pleurisy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Jun 2020 13:41:37 +0000</pubDate>
        </item>
        <item>
            <title>medical gases</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=medical_gases</link>
            <description>medical gases

see also:

	* anaesthetics
	* home oxygen

Calculating amount of gas left in cylinder

	* Assuming the gas is stored in the cylinder in the gaseous state as medical oxygen is:
		* Boyle's law: P1V1 = P2V2
		* Look on the top of the cylinder, it should tell you how many litres when full (V</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Mar 2009 02:22:49 +0000</pubDate>
        </item>
        <item>
            <title>medico-legal issues in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=medicolegal</link>
            <description>medico-legal issues in the ED

see also:

	* your hospital policies relating to medicolegal issues
	* medical indemnity
	* forensic medicine, crimes and prisoners
	* left at own risk / absconding patient / missing patient / competence
	* managing violence or the aggressive patient in the ED
	* searching patients, suspicious behaviour, unknown substance, weapons or crime within the ED
	* professional health care bodies and registration boards
	* ethical issues in emergency medicine
	* consent
	* …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Nov 2020 23:35:41 +0000</pubDate>
        </item>
        <item>
            <title>Hospital policies relating to medicolegal issues</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=medicolegal_hosp</link>
            <description>Hospital policies relating to medicolegal issues

see also main medico-legal index and links

NOTE: the following are generally intranet policies and only available inside the relevant health service

Victoria

Western Health

	* rights and responsibilities of patients (pdf)
	* Western Health Intranet policy consent for video or clinical photography (pdf)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 18 Oct 2008 02:02:39 +0000</pubDate>
        </item>
        <item>
            <title>medical web portals, directories, news aggregators, etc</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=medportals</link>
            <description>medical web portals, directories, news aggregators, etc

see also:

	* medical blogs and podcasts
	* evidence based medicine (EBM)
	* health informatics
	* tips on accessing medical journals online - includes journal search engines, web-based bookmarking, etc.
	* medical search engines
	* patient information sheets

Australian

emergency medicine

	* OzEmedicine.com - this wikipedia and medical blog
	* ACEM website
	* ASEM links resource
	* Emergency Medicine Australasia (EMA) - journal of the A…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Aug 2011 00:39:06 +0000</pubDate>
        </item>
        <item>
            <title>melaena</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=melaena</link>
            <description>melaena

see also:

	* upper GIT bleeding

Introduction

	* melaena is offensive smelly dark black stools caused by large amounts of altered blood from upper GIT bleeding
	* it may or may not be associated with haematemesis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Jun 2019 05:34:07 +0000</pubDate>
        </item>
        <item>
            <title>melanoma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=melanoma</link>
            <description>melanoma

see also:

	* skin cancer
	* neoplasia / cancer / tumours

introduction

	* melanoma is the skin cancer which causes the most deaths as it tends to metastasize early and has proven difficult to treat once it has spread
	* 90% of melanomas are caused by sporadic damage to the genes which occurs by chance exposure to environmental agents such as UV light</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Feb 2026 06:47:14 +0000</pubDate>
        </item>
        <item>
            <title>Things to do around Melbourne</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=melbthingstodo</link>
            <description>Things to do around Melbourne

Day trips

South-West

	* Werribee Mansion
		*  historic rural mansion with large gardens - - free entry to gardens

	* Werribee Open range zoo
	* You Yangs 
		*  nice walks, picnic areas and views across to Melbourne</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 21 Feb 2023 10:22:19 +0000</pubDate>
        </item>
        <item>
            <title>memory</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=memory</link>
            <description>memory

see also:

	* cognition
	* dementia
	* the brain

physiology of memory

	*  &lt;https://www.news-medical.net/news/20190826/Strong-memories-formed-by-teams-of-neurons-firing-in-synchrony.aspx&gt;
		*  it seems that neurons within the hippocampus have a multi-dimensionsal behaviour that responds to sensory inputs as well as keeping track of the temporal time clock sequences of memory events and thus stamping episodic memory with what, when and where components, critical to recall of these events…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Feb 2026 23:20:52 +0000</pubDate>
        </item>
        <item>
            <title>meningitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=meningitis</link>
            <description>meningitis

see also:

	* the child with headache
	* headache
	* causes of, and risk factors for meningitis
	* cerebrospinal fluid (CSF)
	* meningococcal septicaemia
	* meningococcal chemoprophylaxis
	* RCH guideline - meningitis
	* RCH guidline - acute meningococcal disease
	* RCH guideline - headache
	* NSW NETS - bacterial meningitis (pdf)
	* AFTB lectures - meningitis
	* AFTB lectures - meningococcaemia
	* Meningitis Mx wall chart (pdf)

introduction

	* bacterial meningitis and meningococca…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 06:55:08 +0000</pubDate>
        </item>
        <item>
            <title>causes of, and risk factors for meningitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=meningitis_aetiology</link>
            <description>causes of, and risk factors for meningitis

see also:

	* meningitis
	* eosinophilic meningitis - eosinophils predominate the CSF

aetiology of meningitis

non-viral organisms

infants under 2 months age

	* Group B streptococcus, 
	* E. coli and other Gram-negative organisms (usually from UTI source)
	* Listeria monocytogenes, 
	* S. pneumoniae,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Mar 2026 09:45:33 +0000</pubDate>
        </item>
        <item>
            <title>eosinophilic meningitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=meningitis_eosinophilic</link>
            <description>eosinophilic meningitis

see also:

	* causes of, and risk factors for meningitis
	* eosinophilia

potential causes

	* parasites:
		* N fowleri
		* Acanthamoeba
		* Balamuthia
		* angiostrongyliasis - rarely, but most common cause of eosinophilic meningitis in SE Asia
		* G spinigerum
		* Baylisascaris procyonis
		* S stercolaris</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 07 Apr 2012 05:43:23 +0000</pubDate>
        </item>
        <item>
            <title>meningococcal chemoprophylaxis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=meningococcal_prophylaxis</link>
            <description>meningococcal chemoprophylaxis

see also:

	* meningitis
	* meningococcal septicaemia
	* meningococcus

introduction

	* contacts of patients with invasive meningococcal disease should be considered for contact tracing and chemoproprophylaxis.
	* in addition, there are vaccines but these do not cover all subtypes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 04:29:42 +0000</pubDate>
        </item>
        <item>
            <title>meningococcal septicaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=meningococcal_septicaemia</link>
            <description>meningococcal septicaemia

see also:

	* meningitis
	* meningococcus
	* meningococcal chemoprophylaxis
	* RCH guidline - acute meningococcal disease
	* AFTB lectures - meningococcaemia

introduction

	* often presents with acute onset fever, severe muscle pains, vomiting and then drowsiness, confusion, hypotensive septicaemic shock as the petechial rash develops and rapidly becomes purpuric over minutes to hours.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 04:33:28 +0000</pubDate>
        </item>
        <item>
            <title>meningococcus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=meningococcus</link>
            <description>meningococcus

see also:

	* meningococcal septicaemia
	* meningitis
	* meningococcal chemoprophylaxis
	* clinically important bacteria
	* wikipedia

introduction

	* the meningococcus (Neisseria meningitidis) is an obligate aerobe, bean-shaped diplococcus, fastidious, oxidase +ve Gram -ve coccoid
	* only infect humans and have never been isolated from animals because the bacterium cannot get iron other than from human sources (transferrin and lactoferrin).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 04:42:25 +0000</pubDate>
        </item>
        <item>
            <title>meningoencephalitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=meningoencephalitis</link>
            <description>meningoencephalitis

see meningitis and encephalitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 07 Jun 2014 04:07:39 +0000</pubDate>
        </item>
        <item>
            <title>menorrhagia / PV bleeding</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=menorrhagia</link>
            <description>menorrhagia / PV bleeding

see also:

	* gynaecology
	* Emedicine
	* RCH guidelines - Mx of adolescent with menorrhagia

aetiology of abnormal PV bleeding

	* pregnancy-related causes - miscarriage, ectopic, late pregnancy causes such as placenta praevia and abruption, retained products
	* haematologic causes such as warfarin or other anticoagulants, thrombocytopaenia, von Willebrand's disease, etc</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 01:39:59 +0000</pubDate>
        </item>
        <item>
            <title>menstrual cycle</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=menstrual_cycle</link>
            <description>menstrual cycle

see also:

	* gynaecology
	* anovulation and anovulatory menstrual cycles

from wikipedia:



ovulatory menstrual cycle

menstrual cycle length

	* The length of the menstrual cycle is from the first day of menstrual flow to the day before the onset of the next menstrual flow
	* variations are primarily due to variations in length of follicular phase and whether ovulation has occurred or not</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 Jan 2026 23:17:57 +0000</pubDate>
        </item>
        <item>
            <title>Mental Health Act 2014 Victoria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mentalhealthact_vic</link>
            <description>Mental Health Act 2014 Victoria

see also:

	* psychiatry and mental health
	* forensic medicine, crimes and prisoners
	* use of mechanical restraints

Victorian Mental Health ACT 2014

	* the Mental Health Act 2014
	* Vic. Govt resources

	* The MHA assumes that patients not subject to an order have decision-making capacity. 
	* Therefore, as long as they are compliant with the treatment and direction of clinicians they will remain a voluntary patient.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Feb 2023 00:17:21 +0000</pubDate>
        </item>
        <item>
            <title>mental health history and examination</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mentalhealth_exam</link>
            <description>mental health history and examination

	* psychiatry and mental health
	* Mental Health Act 2014 Victoria

Introduction

	* an ability to rapidly assess a patient from a mental health perspective is important
	* this includes monitoring for change over time and this further supports the importance of continual documentation of their mental state to allow comparisons</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 19 May 2022 04:06:44 +0000</pubDate>
        </item>
        <item>
            <title>meralgia paresthetica</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=meralgia</link>
            <description>meralgia paresthetica

see also:

	* paraesthesiae or numbness
	* groin pain
	* wikipedia
	* Emedicine

introduction

	* meralgia paraesthetica comes from the Greek words meros (thigh) and algos (pain).
	* it is due to compression of the lateral cutaneous femoral nerve (LCFN) of the thigh (which arises from L2 and L3 nerve roots), usually as it passes under the lateral aspect of the inguinal ligament ~10-15mm medial to the ASIS, but it may be up to 5cm medial.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 31 May 2013 13:47:50 +0000</pubDate>
        </item>
        <item>
            <title>mercury poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mercury</link>
            <description>mercury poisoning

see also:

	* toxicology
	* Curr Probl Pediatr Adolesc Health Care. 2010. Mercury Exposure and Children’s Health

introduction

	* mercury is a heavy metal which accumulates in the body and also becomes more concentrated in animals higher in the food chain
	* mercury has no known physiologic benefits
	* high levels may cause toxicity and can affect babies in utero as well as during lactation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Dec 2023 13:06:04 +0000</pubDate>
        </item>
        <item>
            <title>meropenem</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=meropenem</link>
            <description>meropenem

see also:

	* antibiotics
	* Tazocin (piperacillin + tazobactam)

introduction

	* a carbapenem broad spectrum antibiotic reserved for use in serious infections

contraindications

	* HS to Beta-lactam antibiotics (incl carbapenem antibiotics, penicillins) 

precautions

	* critically ill patients with Pseudomonas aeruginosa infections (may develop resistance, repeat sensitivity testing recommended);</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 May 2013 08:15:28 +0000</pubDate>
        </item>
        <item>
            <title>Middle Eastern Respiratory Syndrome - Corona Virus (MERS-CoV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mers</link>
            <description>Middle Eastern Respiratory Syndrome - Corona Virus (MERS-CoV)

see also:

	* coronaviridae / corona viruses (CoV)
	* SARS virus
	* viruses
	* how one man spread MERS throughout a South Korean ED in 2015

introduction

	* MERS-CoV currently has a ~50% mortality rate
	* the first reported human infection from MERS-CoV was detected in September 2012.
	* as of October 2013, WHO has been informed of a total of 139 laboratory-confirmed cases of infection with MERS-CoV, including 60 deaths.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 20 May 2020 23:22:29 +0000</pubDate>
        </item>
        <item>
            <title>mesenteric panniculitis (MP) / sclerosing mesenteritis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mesenteric_panniculitis</link>
            <description>mesenteric panniculitis (MP) / sclerosing mesenteritis

see also:

	* the patient with acute RUQ pain in ED

introduction

	* MP is a rare non-malignant disorder characterised by an acute benign fibrosing and inflammatory condition that involves the adipose tissue of the mesentery of the small bowel primarily, although colon is affected in 20%, and rarely it may involve the omentum, pancreas, mesoappendix and pelvis.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 May 2019 01:36:57 +0000</pubDate>
        </item>
        <item>
            <title>mesothelioma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mesothelioma</link>
            <description>mesothelioma

see also:

	* lung cancer
	* neoplasia / cancer / tumours
	* asbestos.com - a US-based resource for patients with mesothelioma

introduction

	* an uncommon cancer (3% of all cancers) which is almost exclusively related to exposure to asbestos with a synergistic effect of smoking
	* it has a latency period of 20-50 years following exposure to asbestos</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Apr 2012 08:06:15 +0000</pubDate>
        </item>
        <item>
            <title>metabolic acidosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=metabolic_acidosis</link>
            <description>metabolic acidosis

see also:

	* acid-base physiology
	* arterial and venous blood gases (ABGs/VBGs)

introduction

	* a primary metabolic acidosis is a derangement of normal physiology characterised by a low arterial pH and a low arterial bicarbonate level.
	* if arterial bicarbonate level is low but pH is high, then this is a compensatory metabolic acidosis which is the body's attempt to correct a prolonged primary respiratory alkalosis event - see</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 11 Sep 2018 05:18:27 +0000</pubDate>
        </item>
        <item>
            <title>metabolic alkalosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=metabolic_alkalosis</link>
            <description>metabolic alkalosis

see also:

	* acid-base physiology
	* arterial and venous blood gases (ABGs/VBGs)

introduction

	* a primary metabolic alkalosis is a derangement of acid-base homeostasis whereby arterial pH and bicarbonate levels are both raised.
	* persistence of a primary metabolic alkalosis usually requires either:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 18 Jan 2010 07:05:13 +0000</pubDate>
        </item>
        <item>
            <title>Metabolic disorders</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=metabolic_disorders</link>
            <description>Metabolic disorders

	* RCH guideline - metabolic disorders
	* RCH guideline - death of a child with suspected metabolic disorder</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 Sep 2008 03:42:35 +0000</pubDate>
        </item>
        <item>
            <title>metabolome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=metabolome</link>
            <description>metabolome

see also:

	* foods that may be toxic or bad for you
	* risk and the perception of risk
	* air pollution and health risks
	* the GIT microbiome
	* genomics
	* proteome
	* exposome and health
	* transcriptome

Introduction

	* the metabolome generally refers to the individual patient's collection of small metabolite molecules (usually &lt; 2000 Daltons) which can be found in the blood or in tissues and which may reflect cellular function at a given point of time</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Aug 2025 00:41:17 +0000</pubDate>
        </item>
        <item>
            <title>metabonomics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=metabonomics</link>
            <description>metabonomics

see also:

	* foods that may be toxic or bad for you
	* risk and the perception of risk
	* air pollution and health risks
	* the GIT microbiome
	* genomics
	* metabolome
	* exposome and health
	* transcriptome
	* proteome

Introduction

	* metabonomics focuses on metabolic changes caused by the exposome and health
	* not to be confused with the metabolome which focuses on small metabolite molecules</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Aug 2025 00:44:05 +0000</pubDate>
        </item>
        <item>
            <title>metamphetamine / meth / ice</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=metamphetamine</link>
            <description>metamphetamine / meth / ice

see also:

	* the meth epidemic video
	* amphetamines and related psychostimulant substances
	* Mx of psychostimulant toxicity from amphetamines and related substances
	* addiction medicine (alcohol and other substance use)
	* managing violence or the aggressive patient in the ED
	* NDARC - Ice Fact Sheet (pdf) or low res. version (pdf)
	* &lt;https://www.abc.net.au/news/science/2019-04-20/chemsex-crystal-meth-ice-sex-risks/10993800&gt;

metamphetamine

	* releases large a…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 Jun 2022 02:36:08 +0000</pubDate>
        </item>
        <item>
            <title>metaraminol (Aramine)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=metaraminol</link>
            <description>metaraminol (Aramine)

see also:

	* inotropes
	* sympathomimetics

introduction

	* a vasopressor which can be used as iv bolus peripherally for short term Mx of hypotension
	* it is particularly useful at induction of anaesthesia to counteract the hypotensive effects of most induction agents in at risk patients where iv fluid bolus is not sufficient.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 13 Apr 2012 04:30:10 +0000</pubDate>
        </item>
        <item>
            <title>metformin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=metformin</link>
            <description>metformin

see also:

	* oral hypoglycaemic agents
	* radiologic contrast media precautions and adverse reactions

introduction

	* a biguanide oral hypoglycaemic agent which is very useful in the treatment of patients with insulin resistance
	* it was developed from the herb Galega officianalis and 1st synthesized in 1922 but overshadowed by the 1st use of insulin in the same year</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Jun 2023 00:53:30 +0000</pubDate>
        </item>
        <item>
            <title>methadone</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=methadone</link>
            <description>methadone

see also:

	* methadone overdose
	* WH intranet ED policy - methadone
	* Addiction medicine - drug and alcohol - main index and links

Introduction

	* an opioid agonist which is well absorbed orally with a long half-life allowing once daily dosing
	* developed in Germany during world war II as a synthetic alternative to morphine as morphine was hard to obtain</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:57:15 +0000</pubDate>
        </item>
        <item>
            <title>methanol poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=methanol</link>
            <description>methanol poisoning

see also:

	* toxicology
	* ethylene glycol poisoning
	* ethanol (alcohol and alcohol withdrawal)

Introduction

	* methanol is a colourless and flammable liquid often used to produce fuel, insecticides, paint strippers, antifreeze, plastics, petrol and solvents and is the primary component of windshield washer fluid.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Dec 2024 22:12:27 +0000</pubDate>
        </item>
        <item>
            <title>methaemoglobinaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=methb</link>
            <description>methaemoglobinaemia

see also:

	* hypoxia
	* Austin Poisons Centre guideline - Mx of methaemoglobinaemia

introduction

	* methaemoglobin (metHb) is a dysfunctional form of Hb that is incapable of carrying oxygen.
	* high levels of metHb result in a form of hypoxia and can be lethal, particularly at levels &gt; 70%.
	* metHb results from either:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 May 2020 06:19:26 +0000</pubDate>
        </item>
        <item>
            <title>methoxyflurane</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=methoxyflurane</link>
            <description>methoxyflurane

see also:

	* anaesthetics
	* pain, analgesia and analgesics
	* Western Health guideline on use of methoxyflurane (pdf) - only available in intranet

introduction

	* methoxyflurane (“Penthrane”) is a volatile fluorinated hydrocarbon inhaled analgesic and anaesthetic agent.
	* it's use as an anaesthetic was ceased in the late 1970's as at anaesthetic concentrations it was found to cause hepatotoxicity and irreversible, dose-dependent nephrotoxicity.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 07:36:21 +0000</pubDate>
        </item>
        <item>
            <title>methylxanthines</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=methylxanthines</link>
            <description>methylxanthines

see also:

	* adenosine
	* asthma
	* paediatric asthma
	* aminophylline
	* Mx of theophylline overdose/toxicity

introduction

	* methylxanthines are a group of structurally similar, stimulant xanthine alkaloid chemicals which primarily act as competitive antagonists of adenosine at purine P1 receptors, and in higher doses, effects from their additional competitive antagonism of phosphodiesterase enzyme results in increased intracellular  cAMP levels (see also</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 22 Feb 2014 02:40:40 +0000</pubDate>
        </item>
        <item>
            <title>metoclopramide (Maxolon)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=metoclopramide</link>
            <description>metoclopramide (Maxolon)

see also:

	* anti-emetics
	* serotonin receptors and pharmacology

introduction

	* a commonly used anti-emetic agent
	* actions include:
		* 5-HT3 antagonist
			* =&gt; actions on GIT myenteric plexus:
				* ⇒ decreased bowel hypermotility &amp; increased gastric emptying

			*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 May 2014 06:44:24 +0000</pubDate>
        </item>
        <item>
            <title>metoprolol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=metoprolol</link>
            <description>metoprolol

see also:

	* beta adrenergic blockers

introduction

	* metoprolol is a relatively cardioselective (ie. beta -1 receptor mainly) beta adrenergic blocking agent without intrinsic sympathomimetic activity.

adverse effects and C/I

	* see beta adrenergic blockers

P/K:

	* rapidly absorbed from GIT
	* rapidly and extensively redistributed to extravascular tissues</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 04 Apr 2014 06:33:44 +0000</pubDate>
        </item>
        <item>
            <title>metronidazole</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=metronidazole</link>
            <description>metronidazole

see also:

	* antibiotics

introduction

	* unknown mechanism of action
		* A derivative of the substituted imidazole compounds;
		* Good oral/rectal absorption means that oral/supp. preps can often be used instead of IV.
		* appears in cerebrospinal fluid, saliva and breast milk in concentrations similar to those found in plasma.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Aug 2011 11:14:16 +0000</pubDate>
        </item>
        <item>
            <title>monoclonal gammopathy of uncertain significance (MGUS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mgus</link>
            <description>monoclonal gammopathy of uncertain significance (MGUS)

see also:

	* multiple myeloma
	* immunoglobulins
	* oncology

introduction

	* the most common (2/3rds of all cases) of a spectrum of diseases called plasma cell dyscrasias which also includes multiple myeloma
	* occurs in around 3% of those aged 50-60yrs, 5% of those aged &gt; 70yrs, and in 10-15% of those aged over 80yrs</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 13 Jun 2021 00:22:26 +0000</pubDate>
        </item>
        <item>
            <title>microbiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=microbiology</link>
            <description>microbiology

see:

	* clinically important bacteria
	* viruses
	* fungi
	* prions
	* parasites
	* bions - non-living &quot;nanobacteria&quot; / nanoparticles
	* vaccines</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 May 2020 13:32:54 +0000</pubDate>
        </item>
        <item>
            <title>fetal-maternal microchimerism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=microchimerism</link>
            <description>fetal-maternal microchimerism

see also:

	* pregnancy
	* autoimmune disease

Introduction

	* there is a bi-directional transfer of cells between mother and fetus in animals with a uterus

Fetal cell transfer

	* fetuses transfer cells (“FMc”) to their mother from 4th week of gestation until delivery</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 14 Apr 2025 02:26:14 +0000</pubDate>
        </item>
        <item>
            <title>midazolam</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=midazolam</link>
            <description>midazolam

see also:

	*  benzodiazepines
	*  anticonvulsants
	*  sedatives, hypnotics and anxiolytics
	*  induction agents

patient information sheets

	* RCH - seizures - safety issues and how to help (pdf)
	* RCH - intranasal midazolam (pdf)
	* RCH - buccal midazolam (pdf)

Summary

	* short-acting water soluble benzodiazepine which can thus be used intranasally, orally as well as iv, im.
	* 95% prot.bound;  T½=2hrs;   Vd = 1.1L/kg; Clear. = 6.6ml/min/kg;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 28 Oct 2013 06:26:15 +0000</pubDate>
        </item>
        <item>
            <title>midodrine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=midodrine</link>
            <description>midodrine

see also:

	* alpha adrenergic agonists
	* sympathomimetics
	* Autonomic dysfunction and autonomic neuropathy

Introduction

	* midodrine is a pro-drug of desglymidodrine which is a peripherally active, selective, alpha adrenergic 1 agonist which is primarily used for the Rx of symptomatic Autonomic dysfunction and autonomic neuropathy|dysautonomia and postural hypotension]] as a result of its widespread vasoconstriction actions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Jul 2019 07:35:02 +0000</pubDate>
        </item>
        <item>
            <title>mid-trimester issues and complications</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=midtrimester</link>
            <description>mid-trimester issues and complications

see also:

	* Obstetrics
	* decreased fetal movements (DFM or RFM)
	* fetal growth restriction (FGR / SGA / IUGR)

Introduction

	* most women have an uneventful 2nd trimester of pregnancy 
	* rate of miscarriage in second TM in low risk patients is only 0.5%
	* the early stages of fetal growth restriction (FGR / SGA / IUGR) may present, or their risk mitigated for identified high risk women</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 02:16:21 +0000</pubDate>
        </item>
        <item>
            <title>mifepristone / RU486</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mifepristone</link>
            <description>mifepristone / RU486

see also:

	* antiprogestogens

introduction

	* a synthetic steroid antiprogestogen used in the termination of pregnancy in the 1st 49 days of gestation
	* as not all women will miscarry with mifepristone alone, they are usually given the prostaglandin misoprostol 36-48hrs (buccal dose of 800mcg) after the dose</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 12 Jul 2020 02:55:33 +0000</pubDate>
        </item>
        <item>
            <title>migraine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=migraine</link>
            <description>migraine

see also:

	* Mx of acute migraine
	* acute unilateral headache
	* headache
	* neurology
	* cervicogenic headache
	* &lt;http://www.sciencemag.org/news/2016/01/feature-will-antibodies-finally-put-end-migraines&gt;

epidemiology:

	* the third most common medical condition worldwide
	* ranks as the seventh most disabling condition in terms of years of life lost to disability
	* of the general population:
		* 24% of females aged 40yrs have migraine</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 22 Feb 2026 04:02:40 +0000</pubDate>
        </item>
        <item>
            <title>Mx of acute migraine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=migraine_mx</link>
            <description>Mx of acute migraine

see migraine, neurology, pain, analgesia and analgesics, headache

see also:

	* NICS - Mx of acute migraine 006 (pdf)

general principles

	* look for alarm symptoms &amp; signs of headaches that may warrant a CT scan or alternate diagnosis
	* in general oral medications in acute attacks are poorly absorbed even with anti-emetic or in non-nauseated pts!!

mild-moderate attack:

	* simple pain, analgesia and analgesics:
		* paracetamol (acetaminophen) +/- codeine</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 28 Dec 2019 21:45:56 +0000</pubDate>
        </item>
        <item>
            <title>milk and dairy products</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=milk</link>
            <description>milk and dairy products

see also:

	* lactation
	* the lactating patient in ED
	* diets and healthy foods

Introduction

	* human breast milk is an amazing substance capable of being the sole food intake to sustain the rapid growth of babies
	* the far majority of infants have a gut enzyme, lactase, which can digest the lactose in milk, however, expression of the gene declines as the child gets older so many adults are relatively intolerant of lactose - the gene to allow high lactase production…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 Mar 2026 11:08:35 +0000</pubDate>
        </item>
        <item>
            <title>Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=minoca</link>
            <description>Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA)

see also:

	* acute myocardial infarction (AMI/STEMI/NSTEMI)
	* troponin

Introduction

	* presumed coronary artery related causes of raised troponin picture consistent with acute myocardial infarction (AMI/STEMI/NSTEMI) but with minimally obstructed coronary arteries on angiography but excludes myocardial causes and type 2</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 07 Jun 2020 12:29:09 +0000</pubDate>
        </item>
        <item>
            <title>mirabegron</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mirabegron</link>
            <description>mirabegron

see also:

	* sympathomimetics
	* overactive bladders, urgency and urge incontinence

Introduction

	* mirabegron is a beta-3 receptor agonist agent which is primarily used in the Rx of overactive bladders, urgency and urge incontinence
	* the bladder wall muscle during the storage phase of bladder filling is mainly relaxed via beta 3 adrenergic stimulation, while the void phase is primarily via muscle contraction due to muscarinic M3 receptor stimulation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Aug 2019 07:24:20 +0000</pubDate>
        </item>
        <item>
            <title>micro RNAs (miRNAs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mirnas</link>
            <description>micro RNAs (miRNAs)

see also:

	* cytokines
	* gene regulation
	* DNA and genes

Introduction

	* 1st discovered in 1993
	* MicroRNAs are small non-coding RNAs and act as fundamental post-transcriptional modulators of several critical cellular processes
	* in most cases, miRNAs interact with the 3′ untranslated region (3′ UTR) of target mRNAs to induce mRNA degradation and translational repression</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 21 Mar 2025 04:09:03 +0000</pubDate>
        </item>
        <item>
            <title>miscarriage</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=miscarriage</link>
            <description>miscarriage

see also:

	* vaginal bleeding in early pregnancy
	* 2nd trimester miscarriage
	* ectopic pregnancy
	* pregnancy and risks of fetal loss
	* Rh isoimmunisation and Anti-D prophylaxis
	* Western Health early pregnancy assessment service (EPAS) referral process
	* DOH Victoria Guidelines on Mx of bleeding in early pregnancy 2011 (pdf)
	* patient information sheets:
		* Western Health ED - early pregnancy loss - Vietnamese version


introduction

	* miscarriage is a common problem, occu…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 29 Jun 2024 08:50:49 +0000</pubDate>
        </item>
        <item>
            <title>2nd trimester miscarriage</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=miscarriage2ndtm</link>
            <description>2nd trimester miscarriage

see also:

	* miscarriage
	* vaginal bleeding in early pregnancy

Introduction

	* whilst 1 in 5 pregnancies do result in miscarriage, the vast majority of these occur in the 1st trimester
	* only 0.5-1% of pregnancies will result in a miscarriage in the 2nd trimester between 13-20 weeks</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Apr 2019 13:22:31 +0000</pubDate>
        </item>
        <item>
            <title>misoprostol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=misoprostol</link>
            <description>misoprostol

see also:

	* miscarriage

introduction

	* synthetic analogue of prostaglandin E1
	* induces contractions of the smooth muscle fibers in the myometrium and relaxation of the uterine cervix.
	* the uterotonic properties of misoprostol should facilitate cervical opening and evacuation of intrauterine debris and is commonly used in Australia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Sep 2013 07:16:19 +0000</pubDate>
        </item>
        <item>
            <title>Molluscum contagiosum</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=molluscum_contagiosum</link>
            <description>Molluscum contagiosum

see also viruses

	* RCH guideline - molluscum
	* RCH patient fact sheet - molluscum contagiosum (pdf)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Jan 2009 12:58:02 +0000</pubDate>
        </item>
        <item>
            <title>monkeypox / mpox (MPVX)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=monkeypox</link>
            <description>monkeypox / mpox (MPVX)

see also:

	* viruses
	* &lt;https://www.cureus.com/articles/122177-all-that-we-need-to-know-about-the-current-and-past-outbreaks-of-monkeypox-a-narrative-review&gt;

	* In Victoria, monkeypox is an urgent notifiable condition, in accordance with Victorian statutory requirements.

Introduction

	* a member of the poxviridae virus family (as with smallpox (SPX)) and immune responses to this family of DNA viruses generally demonstrate cross-reactivity across the various viruses</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 08 Apr 2025 01:11:23 +0000</pubDate>
        </item>
        <item>
            <title>monocytosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=monocytosis</link>
            <description>monocytosis

see also:

	* full blood examination (FBE)
	* neutrophilia
	* lymphocytosis
	* lymphopenia
	* lymphadenopathy

introduction

aetiology

	* recovery phase of neutropenia or an acute infection
	* chronic inflammation such as tuberculosis (TB), syphilis, sbe, inflammatory bowel disease (IBD), rheumatoid arthritis, systemic lupus erythematosus (SLE), sarcoidosis
	* lymphoma
	* chronic myelomonocytic (CMML) or monocytic leukaemia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 12 Aug 2013 15:22:57 +0000</pubDate>
        </item>
        <item>
            <title>morphine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=morphine</link>
            <description>morphine

see also opiates and opioids

Dosage

	* IV bolus: 0.1-0.15mg/kg (usually 2.5mg titrated boluses for adults up to 10-15mg)
	* Infusion: 0.02-0.08mg/kg/hr
	* IM: 10mg (adults) 4h prn
	* maintenance of GA in an intubated patient:
		* usually an infusion of midazolam combined with morphine</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Aug 2011 11:21:43 +0000</pubDate>
        </item>
        <item>
            <title>mottled skin (livedo reticularis)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mottled_skin</link>
            <description>mottled skin (livedo reticularis)

see also:

	* dermatology

Introduction

	* mottled skin (also known as livedo reticularis) is generally pale cool skin with a reticular pattern of venous congestion, usually of all limbs - not just hands and feet as with Raynaud's phenomenon

Aetiology</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 04 Aug 2025 10:46:09 +0000</pubDate>
        </item>
        <item>
            <title>mouthwashes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mouthwashes</link>
            <description>mouthwashes

see also:

	* dental

introduction

	* in general, mouthwashes should only be used for a short period of time to avoid adverse effects, and should never be the sole means of oral hygiene.

chlorhexidine gluconate

	* a cationic bis-guanide with broad spectrum antimicrobial activity</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 23 Dec 2009 03:24:53 +0000</pubDate>
        </item>
        <item>
            <title>mouth ulcers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mouth_ulcers</link>
            <description>mouth ulcers

see also:

	* dermatology

differential diagnoses

apthous ulcers

	* DermNetNZ
	* also known as aphthous stomatitis
	* oval or round ulcers usually on the inside of lips, cheeks or under the tongue where the mucosa is not tightly bound to underlying bone.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2024 05:54:49 +0000</pubDate>
        </item>
        <item>
            <title>magnetic resonance imaging (MRI)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mri</link>
            <description>magnetic resonance imaging (MRI)

see also:

	* radiology

Australian Medicare rebated referrals

	* initially Medicare would only cover MRI referred by specialists
	* GPs CAN refer for MRI in those over age 16yrs for a very restricted range of cases:
		*  MRI brain - unexplained seizures or unexplained chronic headache with suspected intracranial pathology</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Oct 2025 23:43:15 +0000</pubDate>
        </item>
        <item>
            <title>multiple sclerosis (MS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ms</link>
            <description>multiple sclerosis (MS)

for an overview of the neurological assessment see:

	* neurology

introduction

	* an auto-immune disorder of the central nervous system 
	* untreated MS results in significant physical disability during the prime of life for many with the disease</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 20 May 2025 08:22:18 +0000</pubDate>
        </item>
        <item>
            <title>mumps</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mumps</link>
            <description>mumps

see also:

	* viruses

introduction

	* once a very common paediatric viral infection primarily causing swollen bilateral parotid salivary glands, although some developed epididymo-orchitis, meningitis or pancreatitis
	* now very uncommon in countries with high levels of vaccination
	* caused by Rubulavirus which is within the genus Paramyxovirus and is a member of the family</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 12 Jun 2016 22:07:38 +0000</pubDate>
        </item>
        <item>
            <title>mushroom poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mushrooms</link>
            <description>mushroom poisoning

see also:

	* psilocybin (magic mushrooms)
	* Fungimap
	* FungiOz
	* &lt;https://www.rbg.vic.gov.au/science/herbarium-and-resources/identification-and-information-services/edible-and-poisonous-fung&gt;
	* Erowid.org psychoactive mushrooms and plants

Introduction

	* inadvertent ingestion of poisonous mushrooms is a relative common event in Autumn
	* unfortunately in Australia, ingestion of potentially fatal death cap mushrooms (mainly found under oak trees) do tend to occur each A…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 Dec 2025 21:25:52 +0000</pubDate>
        </item>
        <item>
            <title>Murray Valley encephalitis (MVE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mvencephalitis</link>
            <description>Murray Valley encephalitis (MVE)

see also:

	* zoonoses
	* viruses
	* Japanese encephalitis virus (JEV)
	* Ross River virus (RRV)
	* Barmah Forest virus (BFV)
	* &lt;https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/murray-valley-encephalitis&gt;

Introduction

	* a flavivirus related to Japanese encephalitis virus (JEV) and dengue fever transmitted by female mosquitoes mainly along the Murray River region in Australia but it is native to northern Australia
	* there is no person to p…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 09 Dec 2022 00:20:16 +0000</pubDate>
        </item>
        <item>
            <title>myasthenia gravis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=myasthenia_gravis</link>
            <description>myasthenia gravis

see also:

	* neurology
	* Vic Govt notes
	* 

Introduction

	* an autoimmune condition, which, in the early stages, mostly affects the muscles that control eye movement, facial expression, chewing and swallowing. As the condition progresses, neck and limb muscles may also be affected, causing difficulty with holding the head up, walking upstairs and raising the arms, and later breathing may be affected.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 10 Oct 2018 06:44:42 +0000</pubDate>
        </item>
        <item>
            <title>mycobacteria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mycobacterium</link>
            <description>mycobacteria

see also:

	* clinically important bacteria
	* Wikipedia

Mycobacterium tuberculosis complex (MTBC)

	* includes M. tuberculosis, M. bovis, and others
	* see tuberculosis (TB)

Mycobacterium leprae

	* the main organism responsible for leprosy (Hansen's disease).
	* It was discovered in 1873 by the Norwegian physician Gerhard Armauer Hansen, who was searching for the bacteria in the skin nodules of patients with leprosy. It was the first bacterium to be identified as causing diseas…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 May 2022 03:18:04 +0000</pubDate>
        </item>
        <item>
            <title>mycoplasma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=mycoplasma</link>
            <description>mycoplasma

see also:

	* clinically important bacteria

introduction

	* a genus of bacteria that lack a cell wall around their cell membrane and thus are not affected by penicillins or cephalosporins
	* usual antibiotic Rx are with macrolide antibiotics but resistance is increasing
	* if a patient does not respond appropriately to a macrolide, a fluoroquinolone should be added to the treatment regimen</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 11 Jul 2022 08:49:45 +0000</pubDate>
        </item>
        <item>
            <title>myelofibrosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=myelofibrosis</link>
            <description>myelofibrosis

introduction

	* a myeloproliferative disorder in which the proliferation of an abnormal type of bone marrow stem cell results in the replacement of the marrow with collagenous connective tissue fibers and thus fibrosis
	* mainly in those over 50 years age
	* associated with activation of the Janus kinase pathway resulting in increased signalling in some cytokines and growth factors involved in haematopoiesis and immune functions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 24 Nov 2014 10:12:48 +0000</pubDate>
        </item>
        <item>
            <title>multiple myeloma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=myeloma</link>
            <description>multiple myeloma

see also:

	* oncology
	* immunoglobulins
	* serum electrophoresis
	* hypercalcaemia

introduction

	* multiple myeloma is the second most prevalent blood cancer (10%) after non-Hodgkin's lymphoma.
	* It represents approximately 1% of all cancers and 2% of all cancer deaths.
	* the lifetime risk of getting MM in the USA is 1 in 161</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Mar 2026 07:27:33 +0000</pubDate>
        </item>
        <item>
            <title>myeloproliferative disorders</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=myeloproliferative_disorders</link>
            <description>myeloproliferative disorders

see also:

	* neoplasia / cancer / tumours
	* Janus kinase inhibitors

introduction

	* myeloproliferative disorders are a heterogenous group of at least 4 chronic disorders characterized by cellular proliferation of 1 or more hematologic cell lines in the peripheral blood, distinct from acute</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 24 Nov 2014 10:00:19 +0000</pubDate>
        </item>
        <item>
            <title>myocarditis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=myocarditis</link>
            <description>myocarditis

see also:

	* the adult patient with chest pain in the ED
	* acute myocardial infarction (AMI/STEMI/NSTEMI)
	* aortic dissection
	* pulmonary embolism (PE)
	* pericarditis
	* cardiomyopathy
	* LVF or APO
	* cardiogenic shock
	* cardiac tamponade
	* hyperthyroidism
	* 2025 ESC Guidelines for the management of myocarditis and pericarditis: Developed by the task force for the management of myocarditis and pericarditis of the European Society of Cardiology (ESC)

Introduction

	* myocar…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 10 Dec 2025 20:25:46 +0000</pubDate>
        </item>
        <item>
            <title>myopathy / myositis / muscle aches and pains</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=myopathy</link>
            <description>myopathy / myositis / muscle aches and pains

see also:

	* polymyositis (PM)
	* dermatomyositis
	* rhabdomyolysis
	* weakness of the lower limb(s) / weak in the knees
	* sepsis / septicaemia

introduction

	* patients with acute onset generalised aches and pains should be initially worked up to exclude underlying sepsis / septicaemia, even if they are afebrile (consider WCC, CRP, blood cultures, etc) or viraemia such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 20 Oct 2013 00:50:28 +0000</pubDate>
        </item>
        <item>
            <title>N-acetyle cysteine (Parvolex)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nac</link>
            <description>N-acetyle cysteine (Parvolex)

see also:

	*  paracetamol overdose

	* while patients are on Parvolex infusions, pathology investigations which utilise Trinder-like reaction analyses may give falsely low results - examples are lipids, uric acid and lactate.
	* anaphylactoid reactions most likely in high iv administration rates with low serum paracetamol levels</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:46:04 +0000</pubDate>
        </item>
        <item>
            <title>Naegleria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=naegleria</link>
            <description>Naegleria

see also:

	* parasites
	* &lt;http://www.cdc.gov/parasites/naegleria/pathogen.html&gt;
	* MJA 2016 article: Primary amoebic meningoencephalitis in North Queensland 

introduction

	* Naegleria fowleri is an aerobic amoeba which lives in waters at temperatures above 25degC (eg. thermal springs) and can cause rare fatal encephalitis (primary meningoencephalitis (PAM) ) if the 10-35 micron trophozoites gain access to nasal mucosa of humans - such as with playing, swimming, underwater diving i…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 02 Mar 2023 22:17:28 +0000</pubDate>
        </item>
        <item>
            <title>Sodium bicarbonate</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nahco3</link>
            <description>Sodium bicarbonate

see also sodium physiology, acid-base pathophysiology

IV sodium bicarbonate

	* 8.4% sodium bicarbonate:
		* 8.4g per 100ml = 100mmol of sodium and 100mmol of bicarbonate per 100ml = 1mEq/ml

	* usual iv bolus dose:
		* 1mmol/kg = 1ml/kg


Clinical usage of iv sodium bicarbonate</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 03 Nov 2008 04:22:28 +0000</pubDate>
        </item>
        <item>
            <title>non-accidental injury (NAI)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nai</link>
            <description>non-accidental injury (NAI)

see also:

	* paediatric limb fractures

other resources

	* Patterns of skeletal fractures in child abuse: systematic review. BMJ 2008 Oct 2;  Hosted on NICS blog</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 21 Jan 2009 06:41:46 +0000</pubDate>
        </item>
        <item>
            <title>naloxone (Narcan)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=naloxone</link>
            <description>naloxone (Narcan)

see also:

	* opiate and opioid antagonists
	* opiates and opioids
	* heroin or other opiate overdose
	* methadone overdose

Introduction

	* naloxone is an opiate antagonist used to reverse the respiratory depressant effects of opiates and opioids such as heroin
	* it has a short half life of 60-90 minutes which is much shorter than most opiates and thus there is a risk of rebound respiratory depression once it has worn off, and risk of death</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 07 Nov 2017 04:23:36 +0000</pubDate>
        </item>
        <item>
            <title>naltrexone</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=naltrexone</link>
            <description>naltrexone

see also:

	* opiate and opioid antagonists
	* Mx of severe acute opiate withdrawal due to inappropriate use of naltrexone
	* opiates and opioids

introduction

	* naltrexone is a long acting opioid receptor antagonist used in addiction medicine
	* it should NOT be used in opiate-dependent persons within 7-10 days of last opiate dose otherwise there is a high risk of a severe, potentially life threatening acute opiate withdrawal reaction.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 May 2014 04:51:55 +0000</pubDate>
        </item>
        <item>
            <title>Nappy rash</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nappy_rash</link>
            <description>Nappy rash

	* RCH guideline - nappy rash</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 Sep 2008 03:46:01 +0000</pubDate>
        </item>
        <item>
            <title>narcolepsy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=narcolepsy</link>
            <description>narcolepsy

see also:

	* insomnia

introduction

	* narcolepsy is a disorder that sparks sudden daytime bouts of tiredness or sleep
	* it seems that narcolepsy is caused by auto-antibodies which target the protein Trib2 which is produced by neurons that also secrete the substance</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 20 Feb 2010 09:42:29 +0000</pubDate>
        </item>
        <item>
            <title>nasal obstruction</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nasal_obstruction</link>
            <description>nasal obstruction

see also:

	* noisy breathing

Introduction

	* nasal obstruction is usually transient due to rhinitis may there are less common causes and more chronic causes
	* it may cause stertor and snoring

Aetiology

	*  adenoid hypertrophy
		*  congested nose / rhinitis
		*  nasal polyps</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Feb 2019 21:56:48 +0000</pubDate>
        </item>
        <item>
            <title>nasal and nasopharyngeal swabs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nasal_swab</link>
            <description>nasal and nasopharyngeal swabs

see also:

	* pathology

Introduction

	* nasal swabs may be either:
		*  “deep nasal”
			*  only pass 2-3cm into the nose and are thus less “invasive”, more comfortable, less risky but for many infections are less sensitive for detecting the infection</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 08 Jun 2021 04:35:18 +0000</pubDate>
        </item>
        <item>
            <title>nature exposure and benefits to health</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nature_exposure</link>
            <description>nature exposure and benefits to health

see also:

	* depression
	* anxiety
	* stress

Introduction

	* it has been long known that “fresh air and sunshine” along with regular exercise, in particular, walking, are important to health and wellness
	* many studies are now showing there are important psychological and health benefits to getting out into nature</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 Mar 2026 11:16:18 +0000</pubDate>
        </item>
        <item>
            <title>ncbi_esummary</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ncbi_esummary</link>
            <description>Here is a namespace for ncbi_esummary cache.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 19 Aug 2008 12:06:51 +0000</pubDate>
        </item>
        <item>
            <title>neck pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neckpain</link>
            <description>neck pain

see also:

	* non-traumatic upper neck pain
	* neckpain_lower
		*  cervical disc prolapse - usually C5/6 with severe radicular neuropathic pain radiating down arm(s)

	* cervical spine injury
	* cervical lymphadenitis
	* acute neck stiffness may also be due to
		*  meningeal irritation
			*  meningitis
			*  subarachnoid haemorrhage (SAH)

		*  pleural irritation
			*  pneumonia

		*  retropharyngeal abscess</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Apr 2019 00:05:29 +0000</pubDate>
        </item>
        <item>
            <title>non-traumatic upper neck pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neckpain_upper</link>
            <description>non-traumatic upper neck pain

see also:

	* neck pain
	* neckpain_lower

Introduction

	* upper cervical pain is a relatively common condition in adults and is a common cause of cervicogenic headaches
	* there is usually focal tenderness and possibly trigger points and there may be worsening of the pain on ROM testing of the cervical spine</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 24 Apr 2019 23:34:06 +0000</pubDate>
        </item>
        <item>
            <title>open wounds to neck</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neck_openwounds</link>
            <description>open wounds to neck

see also:

	* trauma
	* burns
	* soft tissue trauma

Introduction

	* open wounds such as knife wounds to the neck which penetrate platysma are potentially life threatening with potential for vascular, trachea, oesophageal, nerve injury as well as pneumothorax, etc.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Jan 2026 21:54:09 +0000</pubDate>
        </item>
        <item>
            <title>necrotizing fasciitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=necrotizing_fasciitis</link>
            <description>necrotizing fasciitis

see also:

	* skin necrosis
	* cellulitis

introduction

	* necrotizing fasciitis is a life or limb threatening, generally rapidly progressive infection of the fascia under the skin which soon results in purpura, cutaneous anaesthesia then skin necrosis due to ischaemia from interruption of the perforating arteries supplying the skin via the fascial layer</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 03 Jul 2013 04:50:05 +0000</pubDate>
        </item>
        <item>
            <title>needlestick injury</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=needlestick</link>
            <description>needlestick injury

see also viruses, hepatitis, HIV / AIDS, antiviral agents

	* RCH guideline - needlestick injury

Mx of adults with needlestick injury

	* for staff members, see your hospital's policy on Mx of needlestick injuries there is usually a pack to assist in managing staff.
	* for community acquired non-staff members</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 20 Dec 2017 06:57:24 +0000</pubDate>
        </item>
        <item>
            <title>neonatal jaundice</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neonatal_jaundice</link>
            <description>neonatal jaundice

see also:

	* Victorian Neonatal Handbook - Jaundice in the first two weeks of life, phototherapy 
	* RCH guideline - neonatal jaundice
	* jaundice (icterus)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Aug 2013 09:05:14 +0000</pubDate>
        </item>
        <item>
            <title>neonatal resuscitation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neonatal_resus</link>
            <description>neonatal resuscitation

see also:

	* Neonates
	* Resuscitation
	* Dr Andrew Tagg's video on neonatal resuscitation
	* Victorian Neonatal Resuscitation Project learning packages
		* Flowchart (pdf)
		* &lt;https://www.neoresus.org.au/learning-resources/key-concepts/&gt;

	* Safer Care Vic - neonatal intubation

Apgar Scoring System:

	* not much help in resuscitation, however, an APGAR of 0 at 10 min has such a poor prognosis that further resuscitation attempts are generally considered futile and is a…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Oct 2023 06:16:07 +0000</pubDate>
        </item>
        <item>
            <title>Neonates</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neonates</link>
            <description>Neonates

	* RCH: Recognition of the seriously unwell neonate and young infant
	* nappy rash
	* jaundice (icterus)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 08 Dec 2025 19:55:49 +0000</pubDate>
        </item>
        <item>
            <title>neoplasia / cancer / tumours</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neoplasia</link>
            <description>neoplasia / cancer / tumours

see also:

	* tissue growth disorders
	* oncology
	* pathology
	* neoplasia / cancer aetiologic factors
	* neoplastic spread
	* cytotoxic agents
	* tumour markers
	* cachexia
	* specific tissue tumours:
		* oropharyngeal cancer
		* nasopharyngeal carcinoma
		* oesophageal cancer
		* stomach cancer
		* pancreatic cancer
		* gallbladder and bile duct tumours
		* hepatocellular carcinoma
		* colorectal cancer (bowel cancer)
		* Pseudomyxoma peritonei  (PMP or &quot;jelly be…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 27 Mar 2026 21:57:05 +0000</pubDate>
        </item>
        <item>
            <title>neoplasia / cancer aetiologic factors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neoplasia_aetiology</link>
            <description>neoplasia / cancer aetiologic factors

see also:

	* neoplasia / cancer / tumours

introduction

	* carcinogenesis

modifiable causes

	* 40% of cancers in adults are thought to be attributable to potentially modifiable lifestyle factors:
		*  Cigarette smoking (19% of cases and 29% of cancer deaths)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 16 Apr 2025 00:42:57 +0000</pubDate>
        </item>
        <item>
            <title>neoplastic spread</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neoplasia_spread</link>
            <description>neoplastic spread

see also:

	* neoplasia / cancer / tumours

introduction

	* A dominant clone forms in tumours (selected by microevolutionary process) &amp; this is the sole clone is present in the tumour &amp; in metastases but there may be phenotypic heterogeneity with different receptors, etc. expressed.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 29 Jan 2024 06:39:46 +0000</pubDate>
        </item>
        <item>
            <title>adrenal tumours</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_adrenal</link>
            <description>adrenal tumours

see also:

	* renal malignancies
	* neoplasia / cancer / tumours

introduction

	* 0.6-1.3% of CT scans of the abdomen reveal an incidental adrenal mass - the incidentaloma
	* adrenal masses are present on autopsy of 1.4-9% of people who were not known to have adrenal disease with a rate of 2% in younger adults, rising to 8-10% in the elderly</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 07 Oct 2020 01:19:04 +0000</pubDate>
        </item>
        <item>
            <title>gallbladder and bile duct tumours</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_biliary</link>
            <description>gallbladder and bile duct tumours

see also:

	* neoplasia / cancer / tumours
	* pancreatic cancer

Introduction

	* gallbladder cancers are rare and often diagnosed late with poor prognoses
	* bile duct cancers (cholangiocarcinomas) are often small, difficult to reach and surrounded by inflammation or scar tissue, standard biopsy and cytology methods often fail to give clear diagnosis hence new biomarkers such as BiliSeq have been developed to improve diagnosis sensitivity from below 50% to ove…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 27 Mar 2026 22:32:12 +0000</pubDate>
        </item>
        <item>
            <title>bladder cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_bladder</link>
            <description>bladder cancer

see also:

	* neoplasia / cancer / tumours
	* &lt;http://info.cancerresearchuk.org/cancerstats/types/bladder/index.htm&gt;

Introduction

	* prevalence appears to be falling
	* lifetime risk: 1 in 28 men, 1 in 91 women
	* 90% are aged over 55yrs with average age at diagnosis being 73 yrs

Risk factors

	* smoking
		*  linear relationship between pack years and bladder cancer incidence and peak effect is at 15 cigarettes per day</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 24 Jun 2023 10:44:34 +0000</pubDate>
        </item>
        <item>
            <title>primary brain tumours</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_brain</link>
            <description>primary brain tumours

see also:

	* neoplasia / cancer / tumours
	* brain evolution and development
	* arachnoid cysts
	* CT brain

Introduction

	* most primary brain tumours are meningiomas or gliomas
	* 6% of all malignant primary brain tumours are lymphomas

Meningiomas

	* tumours arising from arachnoidal cap cells in the meninges
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Jan 2026 22:33:52 +0000</pubDate>
        </item>
        <item>
            <title>breast cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_breast</link>
            <description>breast cancer

see also:

	* neoplasia / cancer / tumours
	* US National Cancer Institute - breast cancer prevention, aetiology and genetics

introduction

	* 

risk factors

	* breast cancer risk calculator
	* PH carcinoma-in-situ or carcinoma of breast:
		* ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS) are at increased risk
		* if a woman has had breast cancer, her risk of developing a second primary breast cancer is 2-6 times the risk seen in the general population of d…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 10 Jun 2024 09:27:57 +0000</pubDate>
        </item>
        <item>
            <title>cervical cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_cervical</link>
            <description>cervical cancer

see also:

	* human papilloma virus (HPV)
	* neoplasia / cancer / tumours
	* oncology
	* wikipedia

introduction

	* 500,000 cases world-wide annually
	* 2nd most common gynaecologic malignancy and is essentially a sexually transmitted disease
	* in the early 20th century it was noted that cervical cancer is rare in Jewish women who only have Jewish men as partners, and is rare in virginal nuns, but common in 2nd wives of men whose first wife died from cervical cancer.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Oct 2009 23:51:38 +0000</pubDate>
        </item>
        <item>
            <title>colorectal cancer (bowel cancer)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_colorectal</link>
            <description>colorectal cancer (bowel cancer)

see also:

	* neoplasia / cancer / tumours
	* Low-grade appendiceal mucinous neoplasm (LAMN)
	* &lt;http://info.cancerresearchuk.org/cancerstats/types/bowel/index.htm&gt;

risk factors

	* see &lt;http://www.cancerresearchuk.org/cancer-info/cancerstats/types/bowel/riskfactors/&gt;
	* Australians born after 1990 have twice the risk of colon cancer than those born in 1950, and 4x the risk of rectal cancer - similar trends in many other countries - but the cause of this is not…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 Jan 2026 10:43:05 +0000</pubDate>
        </item>
        <item>
            <title>stomach cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_gastric</link>
            <description>stomach cancer

see also:

	* neoplasia / cancer / tumours
	* &lt;http://gastro.ucsd.edu/fellowship/Documents/GastriCancer-Dong021610.pdf&gt;

introduction

	* 2nd most common cause of cancer-related death in the world
	* remains difficult to cure as most present late
	* 14th most common cancer in Western cultures and ranks about 7th in cancer causes of mortality, and median age at Dx is around 70yrs, with 25% present with localized disease, 31% with regional disease, 32% with metastatic disease</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Jan 2026 22:35:08 +0000</pubDate>
        </item>
        <item>
            <title>hepatocellular carcinoma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_hepatic</link>
            <description>hepatocellular carcinoma

see also:

	* neoplasia / cancer / tumours
	* cirrhosis
	* hepatitis

Introduction

	* globally, liver cancer is the 5th most common cancer in men, and the 7th most common in women
	* 80-90% have cirrhosis as the main risk factor
	* it is rare &lt; 40 years age, and reaches a peak at 70 years age</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 22 Aug 2025 23:49:36 +0000</pubDate>
        </item>
        <item>
            <title>Low-grade appendiceal mucinous neoplasm (LAMN)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_lamn</link>
            <description>Low-grade appendiceal mucinous neoplasm (LAMN)

see also:

	* neoplasia / cancer / tumours
	* colorectal cancer (bowel cancer)

Introduction

	* a rare adenoma malignancies of the appendix (0.4-1% of GIT neoplasms but prevalence rising in Western countries by 3% per annum) with symptoms varying depending on the clinical manifestations</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 May 2022 07:57:03 +0000</pubDate>
        </item>
        <item>
            <title>lung cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_lung</link>
            <description>lung cancer

see also:

	* neoplasia / cancer / tumours
	* palliative care
	* lung lesions

introduction

	* the vast majority of primary lung cancers are carcinomas which are divided into:
		* non small cell carcinoma (NSCLC) - accounts for 80%
		* small cell carcinoma (SMLC) “oat cell” - accounts for 17%</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Mar 2026 06:11:43 +0000</pubDate>
        </item>
        <item>
            <title>nasopharyngeal carcinoma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_nasopharyngeal</link>
            <description>nasopharyngeal carcinoma

see also:

	* neoplasia / cancer / tumours
	* ears, nose and throat surgery (ENT)
	* oropharyngeal cancer

Introduction

	* nasopharyngeal carcinoma is a rare cancer of the naso-pharyngeal region
	* there are 3 main sub types:
		*  type 1: SCC - mainly older adults
		*  type 2: non-keratinizing carcinoma
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Feb 2025 01:00:15 +0000</pubDate>
        </item>
        <item>
            <title>oesophageal cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_oesophagus</link>
            <description>oesophageal cancer

see also:

	* neoplasia / cancer / tumours

introduction

	* the most common tumours of the oesophagus are primary oesophageal tumours - in Australia, over 70% are SCC, the remainder are adenocarcinoma.
	* survival is still poor, particularly if late diagnosis as metastatic disease at diagnosis reducing 12 month survival rates to a third of those with local disease only.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 13 Sep 2025 07:52:11 +0000</pubDate>
        </item>
        <item>
            <title>oropharyngeal cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_oropharyngeal</link>
            <description>oropharyngeal cancer

see also:

	* neoplasia / cancer / tumours
	* human papilloma virus (HPV)
	* nasopharyngeal carcinoma

introduction

	* 0.7% of men will develop oropharyngeal cancer (prior to widespread HPV vaccination)
	* there appears to be 2 distinct groups of oropharyngeal cancer:
		* HPV infection (mainly HPV type 16) related:
			* now accounts for ~70% of oropharyngeal cancers</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Feb 2025 00:59:51 +0000</pubDate>
        </item>
        <item>
            <title>ovarian tumours</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_ovarian</link>
            <description>ovarian tumours

see also:

	* gynaecology
	* the patient with an adnexal mass
	* oncology

introduction

	* ovarian tumours occur in all stages of a woman's life, from childhood, when they are mostly disgerminomas, through the reproductive age, when functional cysts predominate, to menopause when up to 30% of all ovarian tumours are borderline or malignant.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Feb 2026 00:17:23 +0000</pubDate>
        </item>
        <item>
            <title>pancreatic cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_pancreas</link>
            <description>pancreatic cancer

see also:

	* neoplasia / cancer / tumours
	* pancreatitis

Introduction

	* “pancreatic cancer” usually refers to adenocarcinoma of the exocrine pancreatic ducts which accounts for 85% of all pancreatic neoplasia
	* 95% of all malignant pancreatic tumours arise from the exocrine pancreas and are pancreatic ductal adenocarcinomas (PDAC), many of these develop from a precursor lesion called pancreatic intraepithelial neoplasia (PanIN)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 05 Jun 2025 02:27:11 +0000</pubDate>
        </item>
        <item>
            <title>prostate cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_prostate</link>
            <description>prostate cancer

see also:

	* urology
	* neoplasia / cancer / tumours
	* prostate specific antigen (PSA)
	* benign prostatic hyperplasia (BPH)

introduction

	* typically a disease of men over age 50 years, but those at risk tend to be advised screening from age 40 years
	* localised cancer is usually asymptomatic and is usually discovered by the detection of a nodule on rectal examination, or finding an elevated</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 09 Nov 2024 19:39:37 +0000</pubDate>
        </item>
        <item>
            <title>Pseudomyxoma peritonei  (PMP or &quot;jelly belly&quot;)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_pseudomyxoma</link>
            <description>Pseudomyxoma peritonei  (PMP or &quot;jelly belly&quot;)

see also:

	* neoplasia / cancer / tumours

Introduction

	* pseudomyxoma peritonei (PMP) is a rare slowly growing mucin-producing tumor in the abdomen and pelvis which often starts in the appendix but can also rarely arise from mucinous tumors of other sites such as the colon, stomach, pancreas, lung, breast, gallbladder, fallopian tubes, or ovaries</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 16 Nov 2025 08:11:20 +0000</pubDate>
        </item>
        <item>
            <title>renal malignancies</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_renal</link>
            <description>renal malignancies

see also:

	* renal masses and cysts
	* neoplasia / cancer / tumours
	* renal medicine (nephrology)
	* wikipedia - RCC

introduction

	* most malignant tumours of the kidney in adults are renal cell carcinoma
	* the other main primary cancer in adults is urothelial cell carcinoma (UCC) of the renal pelvis (transitional cell carcinoma or TCC)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 02:17:17 +0000</pubDate>
        </item>
        <item>
            <title>skin cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_skin</link>
            <description>skin cancer

see also:

	* neoplasia / cancer / tumours
	* melanoma

Introduction

	* 95% and 99% of skin cancers in Australia are caused by exposure to the sun
	* the average age at diagnosis for non-melanoma skin cancers in Australia is 76 years old
	* melanomas and BCCs can occur in young adults</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Jan 2026 22:13:48 +0000</pubDate>
        </item>
        <item>
            <title>testicular tumours</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_testicular</link>
            <description>testicular tumours

see also:

	* neoplasia / cancer / tumours
	* acute scrotal pain or swelling

Introduction

	*  onset most commonly occurs in males 20 to 34 years old, rarely before 15 years old
	*  most are now highly treatable and usually curable even if spread has occurred
	*  more than 95% of testicular cancers are germ cell tumors (GCTs)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 10 Jan 2025 05:45:39 +0000</pubDate>
        </item>
        <item>
            <title>thyroid cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_thyroid</link>
            <description>thyroid cancer

see also:

	* thyroid physiology and hormones
	* hyperthyroidism
	* Mx of a low TSH
	* thyroid storm
	* Graves disease
	* thyroiditis
	* neoplasia / cancer / tumours

Introduction

	* most commonly is diagnosed between the ages of 35 and 65yrs
	* women 3x more affected than men
	* those of Asian descent have higher prevalence
	* most present as a thyroid nodule or an enlarged lymph node</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 25 Oct 2021 02:03:12 +0000</pubDate>
        </item>
        <item>
            <title>uterine cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_uterine</link>
            <description>uterine cancer

see also:

	* menorrhagia / PV bleeding
	* cervical cancer
	* neoplasia / cancer / tumours
	* gynaecology

risk factors

	* overall risk for all women is 3%
	* genetic:
		*  FH increases risk
			*  hereditary nonpolyposis colon cancer (HNPCC or Lynch syndrome) have 70% chance of endometrial cancer
				*  most cases are caused by a defect in either the mismatch repair gene MLH1 or the gene MSH2</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Mar 2026 21:29:22 +0000</pubDate>
        </item>
        <item>
            <title>vulval cancer</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neo_vulval</link>
            <description>vulval cancer

see also:

	* human papilloma virus (HPV)
	* cervical cancer
	* oncology

introduction

	* like cervical cancer, vulval carcinoma is associated with human papilloma virus (HPV) infection
	* striking increase in vulval intraepithelial neoplasia (VIN) since 1980 with the median age of presentation falling to the mid-30's
		* at least 2/3rds of these women smoke cigarettes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Oct 2009 22:37:48 +0000</pubDate>
        </item>
        <item>
            <title>nephrocalcinosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nephrocalcinosis</link>
            <description>nephrocalcinosis

see also:

	* renal colic
	* urolithiasis / renal stones / renal calculi

Introduction

	* Medullary nephrocalcinosis is a condition characterized by the deposition of calcium salts in the renal medulla and is usually detected by the finding of renal medullary hyperechogenicity on USS or CT scans.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2025 06:09:12 +0000</pubDate>
        </item>
        <item>
            <title>nephrotic syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nephrotic_syndrome</link>
            <description>nephrotic syndrome

see also:

	* renal medicine
	* haematuria
	* glomerulonephritis (GN)
	* RCH guideline - nephrotic syndrome
	* Amer. Family Phys. 2016: Diagnosis and Management of Nephrotic Syndrome in Adults

aetiology

	* glomerulonephritis (GN) - 80% of cases
	* metabolic causes:
		* diabetes mellitus
		* amyloidosis
		* lymphoma
		* neoplasia / cancer / tumours esp. lung cancer
		* multiple myeloma
		* dermatoses
		* HbS
		* myxoedema

	* collagen vascular disorders eg. systemic lupus er…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 05 Aug 2022 22:54:33 +0000</pubDate>
        </item>
        <item>
            <title>Anatomy of the autonomic nervous system</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nerves_autonomic</link>
            <description>Anatomy of the autonomic nervous system

see also: Anatomy main index; autonomic dysfunction and autonomic neuropathy

Parasympathetic (P/S):

	* NB. No P/S fibres to limbs, gonads or suprarenal glands!

Efferent fibres:

Cranial

	* III: pregang. bodies in E-W oculomotor nuclei -&gt; ciliary ganglion;
	* VII: pregang. bodies in inf &amp; sup. salivary nuclei</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 May 2015 05:06:21 +0000</pubDate>
        </item>
        <item>
            <title>nerve agents / nerve gases / CBR weapons</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nerve_agents</link>
            <description>nerve agents / nerve gases / CBR weapons

see also:

	* toxicology
	* polonium poisoning
	* Acetylcholinesterase inhibitors

Introduction

	* man-made chemical agents which primarily affect the nervous system in a similar manner to many pesticides
	* they are generally liquid at room temperature, can mix with water and evaporate readily to odorless or near-odorless vapors which are heavier than air</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 Sep 2020 03:07:16 +0000</pubDate>
        </item>
        <item>
            <title>local anaesthesia nerve blocks</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nerve_blocks</link>
            <description>local anaesthesia nerve blocks

see also:

	* local anaesthetic agents
	* fascia lata / fascia iliacus nerve block
	* femoralNblock
	* &lt;https://www.downstream.org/regional-anesthesia&gt;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Sep 2022 09:30:30 +0000</pubDate>
        </item>
        <item>
            <title>neuritin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neuritin</link>
            <description>neuritin

see also:

	* immunoglobulins

Introduction

	* neuritin, also known as Cpg15, is a highly conserved neuropeptide identified in a 1993 screen for activity-regulated genes in the hippocampus dentate gyrus
	* it regulates synaptic plasticity, neurite growth, neuronal migration, and survival</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Nov 2023 13:00:21 +0000</pubDate>
        </item>
        <item>
            <title>neuroanatomy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neuroanatomy</link>
            <description>neuroanatomy

see also:

	* neurology
	* 2016: where words are stored
		* words appear to be stored in over 100 areas of the brain, spread across both the left and right hemispheres
		* individual words actually appear in multiple spots across the brain map, and a single point can be related to more than one word</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 29 Apr 2016 06:39:33 +0000</pubDate>
        </item>
        <item>
            <title>neuroleptics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neuroleptics</link>
            <description>neuroleptics

see also:

	* neuroleptic malignant syndrome (NMS)
	* phenothiazines
	* chlorpromazine (Largactil)
	* prochlorperazine (Stemetil)
	* haloperidol
	* droperidol (Droleptan)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 26 Jul 2011 08:50:32 +0000</pubDate>
        </item>
        <item>
            <title>neurology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neurology</link>
            <description>neurology

see also:

	* neurosurgery
	* psychiatry and mental health
	* neuroanatomy
	* neurology / acute stroke services at Western Health

neurologic examination:

	* cranial nerve examination
	* sensory &amp; motor testing including dermatomes, myotomes, reflexes, coordination &amp; balance
	* sandnsurf.com - Gate's anatomy of the brainstem rules
	* cognitive testing:
		* cognition
		* mental state - delirium vs dementia vs psychosis
		* AMTS cognitive impairment test
		* CAM confusion assessment te…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 22 Sep 2024 06:00:41 +0000</pubDate>
        </item>
        <item>
            <title>neuropathic pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neuropathic_pain</link>
            <description>neuropathic pain

see also:

	* pain, analgesia and analgesics
	* sensory &amp; motor testing including dermatomes, myotomes, reflexes, coordination &amp; balance
	* Addiction medicine - drug and alcohol
	* Pain Management Research Unit, Sydney

neuropathic pain modulators

types of neuropathic pain include:

	* diabetic neuropathy - pain in feet/ankles in up to 15% of diabetics
		* post-herpetic neuralgia - 7-27% with past herpes zoster &amp; incidence increases with age</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 11 Jul 2025 06:34:10 +0000</pubDate>
        </item>
        <item>
            <title>neurosurgery</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neurosurgery</link>
            <description>neurosurgery

see also:

	* neurology
	* head injury in the adult patient
	* cervical spine injury
	* thoracic spine trauma
	* lumbar spine trauma
	* cauda equina syndrome (CES)
	* acute spinal cord compression
	* intracerebral haemorrhage (ICH) in adults
	* subarachnoid haemorrhage (SAH)
	* The patient with a V-P shunt (VPS)
	* neurosurgery at Western health</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 25 May 2020 01:46:16 +0000</pubDate>
        </item>
        <item>
            <title>neurotrophins</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neurotrophins</link>
            <description>neurotrophins

see also:

	* nerve growth factor (NGF) - binds TrkA receptor
	* brain-derived neurotrophic factor (BDNF) - binds TrkB and p75 receptors
	* Neurotrophin-3 (NT-3) - binds TrkC receptor as well as TrkA, TrkB to a lesser extent
	* Neurotrophin-4 (NT-4)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 22 Feb 2014 00:45:22 +0000</pubDate>
        </item>
        <item>
            <title>neutropenia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neutropenia</link>
            <description>neutropenia

see also:

	* febrile neutropenia
		* defined as as temperature &gt; 38ºC and absolute neutrophil count &lt; 0.5 × 109/L or &lt;1.0 x 109/L and falling rapidly

	* full blood examination (FBE)
	* eosinopenia
	* basophilopenia

introduction

	* usually defined as absolute neutrophil count &lt; 0.5 × 109/L (aka agranulocytosis)
	* it is important as the risk of serious bacterial infection increases as the neutrophil count falls below this level.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:49:15 +0000</pubDate>
        </item>
        <item>
            <title>neutrophilia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neutrophilia</link>
            <description>neutrophilia

see also:

	* full blood examination (FBE)
	* neutropenia
	* neutrophils
	* leukocytosis (high WCC)
	* eosinophilia
	* lymphocytosis

	* remember age-specific reference ranges!
	* total WBC and neutrophil count in neonates younger than 1 week are physiologically higher than those of older children and adults
	* infants &lt; 3 months old have small pool of neutrophils and thus often present with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Aug 2023 07:30:37 +0000</pubDate>
        </item>
        <item>
            <title>neutrophils</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=neutrophils</link>
            <description>neutrophils

see also:

	* full blood examination (FBE)
	* neutropenia
	* neutrophilia
	* innate immunity
	* lymphocytes

Introduction

	* neutrophils are the dominant phagocytic granulocyte, representing up to 60% of all circulating leukocytes and play a key role in the acute stress response and innate immunity and have roles in combating infections from bacteria in particular, but also some viruses</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 10 Dec 2025 20:13:56 +0000</pubDate>
        </item>
        <item>
            <title>nerve growth factor (NGF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ngf</link>
            <description>nerve growth factor (NGF)

see also:

	* neurotrophins
	* NGF on wikipedia

introduction

	* NGF is critical for the survival and maintenance of sympathetic and sensory neurons, without it, these neurons undergo apoptosis
	* causes axonal growth and branching
	* induces expression of VGF Nerve Growth Factor-inducible</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 22 Feb 2014 00:59:58 +0000</pubDate>
        </item>
        <item>
            <title>nasogastric tube insertion</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ngt</link>
            <description>nasogastric tube insertion

see also:

	* Western Health policies (intranet):
		* Adult Nasogastric Tube (NGT) Insertion and Management (docx)
		* WH neonatal and paediatric NGT insertion and management (docx)


NGT insertion

	* in the ED, a Ryles NGT is the tube most likely to be available:
		* it is a wide bore tube available in 10F, 12F, 14F and 16F sizes
		* it can be used for up to 2 weeks</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 18 Dec 2014 04:53:03 +0000</pubDate>
        </item>
        <item>
            <title>nicotine and nicotine replacement Rx for smokers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nicotine</link>
            <description>nicotine and nicotine replacement Rx for smokers

Introduction

	* patients attending hospitals who do not have C/I should be offered at least temporary nicotine replacement Rx whilst they are in hospital to reduce nicotine withdrawal agitation and requests to go outside for a smoke</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:54:18 +0000</pubDate>
        </item>
        <item>
            <title>night club medicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nightclub</link>
            <description>night club medicine

	* see also:
		* toxicology
		* novel psychoactive substances (NPS)


introduction

	* in many cities, the dangers of night clubbing - both traumatic from accidental or criminal events, burns from major fires and pharmacological from the increasing use of both old and new drugs - is becoming a major issue for communities and emergency departments and fuelling the need for development of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Jul 2021 07:29:36 +0000</pubDate>
        </item>
        <item>
            <title>non-invasive positive pressure ventilation (NIPPV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nippv</link>
            <description>non-invasive positive pressure ventilation (NIPPV)

see noninvasive positive pressure ventilation (NPPV or NIPPV)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Apr 2011 06:23:16 +0000</pubDate>
        </item>
        <item>
            <title>nitrates including GTN</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nitrates</link>
            <description>nitrates including GTN

see also:

	* vasodilators
	* acute pulmonary oedema (APO)
	* acute coronary syndromes
	* nitrate and nitrate toxicity / overdose
	* Western Health policies (intranet only):
		* Glyceryl Trinitrate (GTN) Infusion protocol (docx)
		* Medicated Transdermal Patches - Safe Management (docx)


introduction

	* nitrates are direct-acting vasodilators acting on veins primarily at low dose, and also on arteries at higher doses, resulting in:
		* reduced pre-load on the heart and …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 May 2020 06:16:13 +0000</pubDate>
        </item>
        <item>
            <title>nitrofurantoin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nitrofurantoin</link>
            <description>nitrofurantoin

see also:

	* antibiotics
	* urinary tract infections (UTIs) / cystitis

introduction

	* nitrofurantoin is an antibiotic used in the short term Rx of urinary tract infections (UTIs) / cystitis and is generally regarded as a 4th line antibiotic after trimethoprim, cephalexin, and amoxycillin/clavulanic acid
	* it is active against Gram positive and Gram negative urinary tract pathogens, particularly E. coli, but Ps. aeruginosa and some Klebsiella, Aerobacter and Proteus strains a…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Dec 2014 06:54:09 +0000</pubDate>
        </item>
        <item>
            <title>sodium nitroprusside</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nitroprusside</link>
            <description>sodium nitroprusside

see also:

	* vasodilators
	* antihypertensives

introduction

	* potent, rapid direct-acting that greatly reduces arterial blood pressure
		* relaxes both venous and arterial circulation
		* half-life of nitroprusside is 2 minutes (metabolised to cyanide by eryythrocytes then to thiocyanate in the liver)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Oct 2013 07:14:42 +0000</pubDate>
        </item>
        <item>
            <title>nitrous oxide</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nitrous_oxide</link>
            <description>nitrous oxide

see also:

	* toxicology
	* pain, analgesia and analgesics

Introduction

	* a commonly used anesthetic, inhaled analgesic agent
	* also readily available to the public as used to inflate balloons and in whipping cream and thus is subject to chronic abuse
	* commonly abused in the form of nangs which are small canisters of nitrous oxide designed to make cream fluffy and long-lasting</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 24 Jan 2026 22:11:39 +0000</pubDate>
        </item>
        <item>
            <title>non-invasive ventilation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=niv</link>
            <description>non-invasive ventilation

see also:

	* oxygen
	* hypoxia
	* rapid sequence induction (RSI) for emergency intubation
	* noninvasive positive pressure ventilation (NPPV or NIPPV)
	* the LTV 1200 ventilator</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Jul 2014 09:27:00 +0000</pubDate>
        </item>
        <item>
            <title>neuro-muscular blockers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nmblockers</link>
            <description>neuro-muscular blockers

see also:

	* anaesthetics

introduction

	* neuro-muscular blocking agents (NMBAs) are those that paralyse muscle activity by blocking normal transmission at the neuro-muscular junctions of skeletal muscle.
	* there are two main groups of agents:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Aug 2016 11:04:58 +0000</pubDate>
        </item>
        <item>
            <title>N-methyl-D-aspartate (NMDA) and NMDA receptors (NMDAR)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nmda</link>
            <description>N-methyl-D-aspartate (NMDA) and NMDA receptors (NMDAR)

see also:

	* neurology
	* ketamine

Introduction

	* NMDA is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 16 Feb 2025 22:45:28 +0000</pubDate>
        </item>
        <item>
            <title>neuroleptic malignant syndrome (NMS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nms</link>
            <description>neuroleptic malignant syndrome (NMS)

see also:

	* heat illness and heat stroke
	* anti-psychotic medications
	* toxicology
	* CMAJ. 2010 Dec 14; 182(18): E834–E838. Neuroleptic malignant syndrome: a neuroimmunologic hypothesis
	* Curr Neuropharmacol. 2015 May; 13(3): 395–406. Neuroleptic Malignant Syndrome: A Review from a Clinically Oriented Perspective

Introduction

	* see also serotonin syndrome (this link gives comparative DDx features)
	* this is a life threatening disorder in patients w…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Dec 2019 05:56:28 +0000</pubDate>
        </item>
        <item>
            <title>fracture neck of femur (#NOF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nof</link>
            <description>fracture neck of femur (#NOF)

see also:

	* orthopaedics in the ED
	* hip pain
	* osteoporosis

introduction

	* fracture NOF is a common ED presentation and timely recognition, analgesia, referral, ward admission for previon of decubitis ulcers, and care of comorbidities are required to ensure early surgery (preferably within 36 hours) which is required if one wishes to avoid increased risk of morbidity or mortality.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:45:50 +0000</pubDate>
        </item>
        <item>
            <title>noisy breathing</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=noisy_breathing</link>
            <description>noisy breathing

see also:

	* stridor
	* wheeze
	* stertor
	* snoring
	* obstructive sleep apnoea (OSA)
	* Stridor vs Wheeze vs Stertor and snoring in children (pdf)

Introduction

	* noise during breathing can be of various types depending upon whether awake or asleep and on where the airway obstruction arises
	* wheeze is primarily an expiratory musical sound coming from the lungs but may become biphasic and is usually caused by</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Feb 2019 21:48:36 +0000</pubDate>
        </item>
        <item>
            <title>noradrenaline / norepinephrine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=noradrenaline</link>
            <description>noradrenaline / norepinephrine

see also:

	* inotropes
	* sympathomimetics
	* Safer Care Victoria - Norepinephrine

introduction

	* noradrenaline is the preferred 1st line vasopressor in Mx of sepsis / septicaemia not responding to iv fluid therapy
	* an endogenous sympathomimetic agent, its main action is as a alpha-1 agonist with beta-1 agonist actions and little beta-2 agonist actions (thus no skeletal muscle vasodilation nor the glucose metabolism effects as with adrenaline)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Jul 2019 07:10:54 +0000</pubDate>
        </item>
        <item>
            <title>norovirus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=norovirus</link>
            <description>norovirus

see also:

	* gastroenteritis
	* diarrhoea
	* food poisoning
	* viruses

Introduction

	* one of the most common causes of acute gastroenteritis (18% of global cases), and presents as sudden onset vomiting and diarrhoea
	* it is highly contagious and is more common in winter
	* outbreaks occur in residential care facilities, hospitals, schools and child care centres</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Jun 2019 10:25:44 +0000</pubDate>
        </item>
        <item>
            <title>novel psychoactive substances (NPS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nps</link>
            <description>novel psychoactive substances (NPS)

	* see also:
		* toxicology
		* night club medicine


Introduction

	* many of these drugs are transient on the marketplace
	* in 2021, the Victorian Coroner had identified 5 recent cases of deaths from 25C-NBOme and 5-flouroamphetamine with the victims thinking they were taking ecstasy or psilocybin.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Jun 2023 00:19:48 +0000</pubDate>
        </item>
        <item>
            <title>non-steroidal anti-inflammatory drugs (NSAIDs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nsaids</link>
            <description>non-steroidal anti-inflammatory drugs (NSAIDs)

see also eicosanoids including prostaglandins, pain, analgesia and analgesics, salicylate poisoning, aspirin (acetylsalicylic acid), colchicine

introduction

	* NSAIDs are a group of drugs which have anti-inflammatory and analgesic effects via their inhibitory action upon cyclooxygenase (COX) which is involved in the synthesis of prostaglandins.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 21 Feb 2020 23:22:56 +0000</pubDate>
        </item>
        <item>
            <title>nystagmus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=nystagmus</link>
            <description>nystagmus

see also:

	* vertigo - peripheral vs central

Introduction

	* with normal eyesight, while the head rotates about an axis, distant visual images are sustained by rotating eyes in the opposite direction of the respective axis
		*  the semicircular canals in the vestibule of the ear sense angular acceleration, and send signals to the nuclei for eye movement in the brain.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 22 May 2021 06:52:16 +0000</pubDate>
        </item>
        <item>
            <title>musical beat perception</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_beatperception</link>
            <description>musical beat perception

see also:

	* neurology

Introduction

	* Moving in synchrony to a musical beat encompasses:
		*  beat perception and extraction
			*  beat perception and production do not depend on musical training or music genre, and atypical beat synchronization is not linked to lack of music exposure</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 17 Jun 2022 00:51:13 +0000</pubDate>
        </item>
        <item>
            <title>cognition</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_cognition</link>
            <description>cognition

see also:

	* neurology
	* dementia
	* cognitive testing:
		* mental state - delirium vs dementia vs psychosis
		* AMTS cognitive impairment test
		* CAM confusion assessment test for diagnosis of delirium
		* Clock test - a measure of frontal and executive functioning and need for further dementia testing
		* Geriatric depression scale
		* Mini-mental state examination
		* Modified Mini-Cog Test
		* Differentiating conversion disorder from malingering
		* Western Health CPG 8.2 Cogni…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 26 Aug 2019 22:59:49 +0000</pubDate>
        </item>
        <item>
            <title>Conversion disorder</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_conversion</link>
            <description>Conversion disorder

see neurology

Suspected conversion disorder or malingering:

	* the diagnosis of a psychogenic disorder is always a diagnosis of exclusion

conversion disorders:

	* pt is not aware of the lack of organic basis
	* symptoms may be brought on or altered by suggestion</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Nov 2008 00:29:14 +0000</pubDate>
        </item>
        <item>
            <title>delirium</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_delirium</link>
            <description>delirium

see also:

	* neurology
	* RANZCP: Practice Guideline 10, 2009, Antipsychotic medications as a treatment of behavioural and psychological symptoms in dementia (pdf)
	* Australian and New Zealand Society for Geriatric Medicine. Position Statement 13. Delirium in Older People. Revised 2012. (pdf)

introduction

	* delirium is common in elderly hospital inpatients and is associated with increased morbidity and mortality
	* early recognition, investigation and management with appropriate i…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:33:43 +0000</pubDate>
        </item>
        <item>
            <title>Autonomic dysfunction and autonomic neuropathy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_dysautonomia</link>
            <description>Autonomic dysfunction and autonomic neuropathy

see also neurology; sympathomimetics; parasympathetics; anatomy of the autonomic nervous system

Autonomic dysequilibrium:

	* The development of profound autonomic dysfunction and of neuroendocrine activation characterizes and possibly contributes to the progression of heart disease to congestive heart failure. Sympathetic activation is a generalized process and the proposed mechanisms for neurohumoral activation include decreased input from excit…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Jul 2019 06:54:19 +0000</pubDate>
        </item>
        <item>
            <title>References for autonomic dysfunction</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_dysautonomia_refs</link>
            <description>References for autonomic dysfunction

see autonomic dysfunction

References

	* Autonomic Peripheral Neuropathies: Clinical Presentation, Diagnosis, and Treatment.[Review]. Journal of Clinical Neuromuscular Disease. 2(3):147-157, March 2001.
	* Autonomic neuropathy, I. Clinical features, investigation, pathophysiology, and treatment. [Review]. Journal of the Neurological Sciences. 137(2):79-88, 1996 May.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Nov 2008 01:06:25 +0000</pubDate>
        </item>
        <item>
            <title>Cranial nerve examination</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_exam_cranialn</link>
            <description>Cranial nerve examination

see also:

	* neurology
	* anatomy of the autonomic nervous system
	* LITFL - the rule of 4 of the brainstem

NB. Myasthenia gravis has the ability to mimic virtually any cranial neuropathy, including isolated third nerve palsies and INO. Myasthenia gravis must remain a possible diagnosis when encountering a third nerve palsy, especially when the course is variable or atypical.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 05 Dec 2021 23:46:52 +0000</pubDate>
        </item>
        <item>
            <title>sensory &amp; motor testing including dermatomes, myotomes, reflexes, coordination &amp; balance</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_exam_sensorimotor</link>
            <description>sensory &amp; motor testing including dermatomes, myotomes, reflexes, coordination &amp; balance

see also:

	* neurology
	* touch
	* paraesthesiae or numbness
	* anatomy of the autonomic nervous system
	* Wikipedia: Dermatome chart
	* Wikipedia: innervation of upper limbs

&lt;http://upload.wikimedia.org/wikipedia/commons/thumb/4/47/Dermatoms.svg/1000px-Dermatoms.svg.png&gt;

&lt;http://upload.wikimedia.org/wikipedia/commons/d/de/Gray812and814.PNG&gt;
&lt;http://upload.wikimedia.org/wikipedia/commons/b/bf/Gray826and8…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Feb 2026 21:29:17 +0000</pubDate>
        </item>
        <item>
            <title>facial nerve palsy / Bell's palsy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_facialnpalsy</link>
            <description>facial nerve palsy / Bell's palsy

see also:

	* neurology 
	* cranial nerve examination
	* Ramsay Hunt Syndrome
	* neuromuscular.wustl.edu - full list of DDx of facial N palsy, etc
	* &lt;https://www.jems.com/articles/print/volume-39/issue-5/features/differentiating-facial-weakness-caused-b.html?c=1&gt;
	* ER doctors get the clinical diagnosis of Bell's palsy correct in over 99% of cases without CT scanning

patient information sheets

	* RCH - Bell's palsy (pdf)

basic anatomy

	* see also: &lt;https:/…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Mar 2019 14:02:18 +0000</pubDate>
        </item>
        <item>
            <title>HINTS exam for vertigo and stroke</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_hints</link>
            <description>HINTS exam for vertigo and stroke

see also:

	* ED Mx of stroke
	* vertigo - peripheral vs central
	* ED Mx of vertigo and BPV

Introduction

	* HINTS is a 3-part neurologic exam designed to improve the sensitivity for detection of stroke in patients with acute vertigo / acute vestibular syndrome (AVS) compared with CT scanning and consists of:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 23 Jan 2018 02:34:30 +0000</pubDate>
        </item>
        <item>
            <title>insomnia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_insomnia</link>
            <description>insomnia

see also:

	* sleep hygiene
	* physiology of sleep
	* fatigue
	* managing jet lag and the body clock;
	* Coping with shift work
	* stress
	* psychiatry and mental health
	* sedatives, hypnotics and anxiolytics
	* narcolepsy

Introduction:

	* see physiology of sleep for details on control of sleep, sleep requirements, etc.
	* consequences of acute sleep deprivation include:
		* impaired passive vigilance
		* impaired reaction time</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 24 Aug 2013 01:20:48 +0000</pubDate>
        </item>
        <item>
            <title>Managing jet lag and your body clock</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_jetlag</link>
            <description>Managing jet lag and your body clock

see also: insomnia; sleep hygiene; travel medicine;

This article is a summary of The Lancet Vol 369 March 31, 2007 by Waterhouse et al.

What is jet lag?

	* jet lag is a form of travel fatigue that results from the effects of a new time zone on an unadjusted body clock.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 23 Dec 2009 05:10:21 +0000</pubDate>
        </item>
        <item>
            <title>Mental state - delirium vs dementia vs psychosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_mental_state</link>
            <description>Mental state - delirium vs dementia vs psychosis

see also:

	* neurology
	* delirium
	* dementia
 Delirium  Dementia  Psychosis  Onset  Rapid  Slow  Rapid  Pattern  Fluctuating  Fluctuating-stable  Stable  Oriented  No  Yes  No  Attention  Disordered  Normal  Delusional  Cognition</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 26 Jul 2011 07:12:06 +0000</pubDate>
        </item>
        <item>
            <title>Modified Mini-Cog Test</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_minicog</link>
            <description>Modified Mini-Cog Test

see also:

	* neurology
	* Mini-mental state examination
	* Clock Drawing Test print out (pdf)

Scoring tool
 max. pointspatient scoreorientation    What is the (day of week) (year) (day or night) (last meal) (how long in hospital)?  5   Where are we? (city/state)(hospital)(floor)  3   registration:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Apr 2010 11:03:00 +0000</pubDate>
        </item>
        <item>
            <title>Mini-mental state examination</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_minimental</link>
            <description>Mini-mental state examination

see also:

	* neurology
	* Modified Mini-Cog Test
	* Mini mental state calculator tool

Introduction

	* see &lt;http://www.minimental.com&gt;
	* Scores &lt; 24 suggest a dementing illness but this test is insensitive for mild cognitive impairment and lacks diagnostic specificity for dementia and does not take into account levels of education, premorbid ability &amp; other patient variables such as visual problems or poor English.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Apr 2010 10:26:00 +0000</pubDate>
        </item>
        <item>
            <title>motor neurone disease (MND)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_mnd</link>
            <description>motor neurone disease (MND)

see also:

	* Cranial nerve examination
	* Neuropathies
	* bulbar palsy and pseudobulbar palsy

Introduction

	* a group of progressive neuronal degenerative diseases with generally poor prognosis
	* when one talks on MND, they are usually referring to ALS which is a type of motor neuron disease</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 30 Mar 2026 04:46:52 +0000</pubDate>
        </item>
        <item>
            <title>Neuropathies</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_neuropathies</link>
            <description>Neuropathies

see neurology

Mononeuropathies:

definition:

	* lesions of individual nerve bundles

aetiology:

	* trauma, compression
	* causes that may result in more than one nerve affected (ie. mononeuritis multiplex):
		* acute (usually vascular):
			*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 02 Oct 2017 13:13:35 +0000</pubDate>
        </item>
        <item>
            <title>paraesthesiae or numbness</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_paraesthesia</link>
            <description>paraesthesiae or numbness

see also:

	* neurology
	* pruritus or itching
	* touch
	* pain

introduction

	* numbness may be caused by a multitude of aetiologies ranging from central pathologies involving the brain or spinal cord, peripheral nerve pathologies either involving only one nerve or a number of them, or metabolic abnormalities such as hypocalcaemia or toxins.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Sep 2024 05:13:14 +0000</pubDate>
        </item>
        <item>
            <title>peripheral neuropathy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_peripheral_neuropathy</link>
            <description>peripheral neuropathy

see also:

	* neurology
	* paraesthesiae or numbness

aetiology

	* idiopathic
	* metabolic
		* diabetes mellitus
		* amyloidosis
		* acute intermittent porphyria (AIP)
		* chronic renal failure
		* dysproteinaemia

	* vitamin deficiency
		* B12 deficiency (subacute combined degeneration)
			*  dietary
			*  gastric causes of lack of intrinsic factor production impairing GIT absorption</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 05 Oct 2024 08:24:34 +0000</pubDate>
        </item>
        <item>
            <title>restless legs syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_restlesslegs</link>
            <description>restless legs syndrome

see also insomnia; sleep hygiene

introduction:

	* effects 5-15% of population with varying severity and effect of ability to get to sleep
	* can begin at any age
	* early onset suggests hereditary form (50% have a family history)
	* late onset suggests secondary cause</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 30 Oct 2024 13:05:29 +0000</pubDate>
        </item>
        <item>
            <title>reflex sympathetic dystrophy (RSD) / complex regional pain syndrome / causalgia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_rsd</link>
            <description>reflex sympathetic dystrophy (RSD) / complex regional pain syndrome / causalgia

see also:

	* neurology
	* erythromelalgia - episodic, chronic burning skin pain mainly feet but can affect hands, legs, arms, face
	* Vic. Better Health Channel - pt. info sheet - RSD 

introduction

	* types of complex regional pain syndrome (CRPS):</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 19 Jun 2025 07:28:54 +0000</pubDate>
        </item>
        <item>
            <title>Spinal cord syndromes and lesions</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_spinalcord</link>
            <description>Spinal cord syndromes and lesions

see also:

	* neurology
	* sensory &amp; motor testing including dermatomes, myotomes, reflexes, coordination &amp; balance
	* acute spinal cord compression
	* spinal cord ischaemia / spinal TIA
	* acute thoracic back pain in the adult

Arterial supply of the cord:

	* see spinal cord ischaemia / spinal TIA

2 main sources:

	* paired vertebral arteries form the rostral origin of:
		* single anterior spinal artery
			* runs the entire length of cord in midline supplies…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Sep 2024 05:14:37 +0000</pubDate>
        </item>
        <item>
            <title>acute spinal cord compression</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_spinalcordcomp</link>
            <description>acute spinal cord compression

see also:

	* neurology
	* neurosurgery
	* oncology
	* spinal stenosis
	* cauda equina syndrome (CES)
	* spinal cord syndromes and lesions
	* sensory &amp; motor testing including dermatomes, myotomes, reflexes, coordination &amp; balance

Acute spinal cord compression:

common tumours:

	* breast carcinoma
	* lung carcinoma
	* NHL &amp; Hodgkin's lymphoma
	* multiple myeloma
	* prostate carcinoma

summary:

	* 65% thoracic, 20% lumbosacral spine, 15% cervical</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 24 Sep 2018 13:21:46 +0000</pubDate>
        </item>
        <item>
            <title>AMTS cognitive impairment test</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_test_amts</link>
            <description>AMTS cognitive impairment test

see also neurology

General points

	* Ensure the patient is wearing glasses and/or hearing aids if required and assess the need for an interpreter.
	* Daily testing may be indicated during hospital admission
	* The abbreviated Mental Test Score (AMTS) provides a reliable screen for patients with a high suspicion index for cognitive impairment with noted problems in memory and thinking /speech.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 30 Oct 2008 02:52:34 +0000</pubDate>
        </item>
        <item>
            <title>CAM confusion assessment test for diagnosis of delirium</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_test_cam</link>
            <description>CAM confusion assessment test for diagnosis of delirium

see also:

	* neurology
	* delirium

General points

	* Ensure the patient is wearing glasses and/or hearing aids if required and assess the need for an interpreter.
	* Daily testing may be indicated during hospital admission</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Apr 2010 11:05:00 +0000</pubDate>
        </item>
        <item>
            <title>Clock test</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_test_clock</link>
            <description>Clock test

see also:

	* neurology
	* Clock Drawing Test print out (pdf)

General points

	* Ensure the patient is wearing glasses and/or hearing aids if required and assess the need for an interpreter.
	* the clock test is a test of frontal and executive functioning and assess the need for further cognitive testing and screen for dementia.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Apr 2010 11:09:00 +0000</pubDate>
        </item>
        <item>
            <title>Geriatric depression scale</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_test_gerdepscale</link>
            <description>Geriatric depression scale

see also:

	* geriatrics
	*  neurology
	*  depression

General points

	* Score 1 point for each positive response
	* A score of 3 or more may be indicative of a depressive disorder and a more detailed assessment is required

Geriatric depression scale questions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 17 Jun 2019 14:52:18 +0000</pubDate>
        </item>
        <item>
            <title>vertigo - peripheral vs central</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_vertigo</link>
            <description>vertigo - peripheral vs central

see also

	* neurology
	* examination of cranial nerves
	* ataxia
	* stroke (CVA)
	* transient ischaemic attack (TIA)
	* ED Mx of vertigo including BPV instructions

peripheral vs central vs systemic cause

peripheral vertigo features

	* see HINTS exam for vertigo and stroke

nystagmus characteristics

	* horizontal or horizontorotary (esp. Meniere's which can last for hours)
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 16 Sep 2018 08:00:02 +0000</pubDate>
        </item>
        <item>
            <title>acute weird neurology symptoms</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=n_weird</link>
            <description>acute weird neurology symptoms

see also:

	* neurology

introduction

	* sometimes patients present with neurologic symptoms which don't fit simple single anatomic neurology pattern
	* usual neurology patterns are those such as:
		* stroke patterns
		* Spinal cord syndromes and lesions
		* Neuropathies
		* peripheral neuropathy
		* myasthenia gravis
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 07 Jul 2016 09:29:27 +0000</pubDate>
        </item>
        <item>
            <title>the obese patient in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=obese_pt</link>
            <description>the obese patient in the ED

see also:

	* obesity and weight management
	* lipoedema
	* the bariatric patient in the ED
	* steatohepatitis (fatty liver)

introduction

	* the obese patient with a BMI &gt; 30 who presents to ED:
		* is ~15% more likely to have a failed iv cannulation 
		* is twice as likely to have an AXR ordered
		* is 30% more likely to have cardiac enzymes ordered</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 22 Mar 2023 22:16:01 +0000</pubDate>
        </item>
        <item>
            <title>obesity and weight management</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=obesity</link>
            <description>obesity and weight management

	* the obese patient in the ED
	* lipoedema
	* steatohepatitis (fatty liver)
	* diabetes mellitus
	* adipokines and adipose-derived hormones
	* carbohydrates and sugars
	* Victoria health Pathways Mx of obesity
	* RCH guideline - obesity and weight management

Introduction

	* obesity is a complex major increasing global health issue
	* there are 3 types of fat cells:
		*  white fat cells found in white adipose tissue (WAT) which serve mainly as energy reserves</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 24 Dec 2025 04:20:10 +0000</pubDate>
        </item>
        <item>
            <title>Obstetrics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=obstetrics</link>
            <description>Obstetrics

	* Drugs in pregnancy and lactation/breastfeeding (via ETG)
	* Drugs in pregnancy (via TGA)
	* NSW NETS - tocolysis for pre-term labour (pdf)
	* NSW NETS - Magnesium sulphate for eclampsia (pdf)
	* NSW NETS - Hydralazine for hypertension in pre-eclampsia (pdf)
	* Vic. DHS - Standards of maternity care (pdf)

in this wiki

	* pregnancy
		* hyperemesis gravidarum
		* Rh isoimmunisation and Anti-D prophylaxis
		* varicella in pregnancy
		* PV bleeding in early pregnancy - miscarriage, e…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 Aug 2019 06:35:39 +0000</pubDate>
        </item>
        <item>
            <title>decreased fetal movements (DFM or RFM)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=obst_dfm</link>
            <description>decreased fetal movements (DFM or RFM)

see also:

	* Obstetrics
	* Safer Care Vic guidelines DFM
	* WH guidelines - intranet only

Introduction

	* most women can feel fetal movements by 20 weeks gestation and these rapidly acquire a regular pattern
	* although fetal movements tend to plateau by 32 weeks of gestation, there is no reduction in the frequency of fetal movements in the late third trimester</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 Aug 2019 10:09:06 +0000</pubDate>
        </item>
        <item>
            <title>fetal growth restriction (FGR / SGA / IUGR)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=obst_fgr</link>
            <description>fetal growth restriction (FGR / SGA / IUGR)

see also:

	* pregnancy
	* decreased fetal movements (DFM or RFM)
	* Obstetrics
	* RANZCOG guidelines
	* WH guideline - intranet only

Introduction

	* Small for Gestation Age (SGA) refers to a fetus with an estimated weight (EFW) and/or abdominal circumference (AC) less than the 10th centile.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Aug 2019 08:06:20 +0000</pubDate>
        </item>
        <item>
            <title>obsessive compulsive disorder (OCD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ocd</link>
            <description>obsessive compulsive disorder (OCD)

see also:

	* psychiatry and mental health

introduction

	* almost 10% of people have subclinical OCD symptoms, while 2% of people have the disabling disorder which impacts their life
	* it is in the top 10 disabling medical conditions, although most suffer in silence, rarely seeking help as they are either embarrassed or perceive that their symptoms will be seen as trivial</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Oct 2015 12:51:19 +0000</pubDate>
        </item>
        <item>
            <title>combined oral contraceptive pill (OCP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ocp</link>
            <description>combined oral contraceptive pill (OCP)

see also:

	* gynaecology; 
	* contraception; 
	* flying and DVT risk with OCP

Introduction

	* the combined oestrogen/progesterone oral contraceptive pill is perhaps the most common form of contraception
	* in 2025, a vaginal ring pessary (NuvaRing) which releases and oestrogen &amp; progesterone over 3 weeks was approved by the Australian PBS - must be removed at 3 weeks then a normal menstrual period should ensue, has a 99.5 per cent efficacy rate with per…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 27 Oct 2025 22:05:31 +0000</pubDate>
        </item>
        <item>
            <title>obsessive compulsive personality disorder (anankastic PD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ocpd</link>
            <description>obsessive compulsive personality disorder (anankastic PD)

see also:

	* psychiatry and mental health
	* obsessive compulsive disorder (OCD)
	* personality disorders

introduction

	* a personality disorder characterised by perfectionism, orderliness, and rigidity
	* it is NOT obsessive compulsive disorder (OCD) although many do develop obsessive compulsive disorder (OCD)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Oct 2015 12:36:05 +0000</pubDate>
        </item>
        <item>
            <title>acetylcholinesterase inhibitor poisoning / organophosphate pesticides</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odacheis</link>
            <description>acetylcholinesterase inhibitor poisoning / organophosphate pesticides

see also:

	* acetylcholinesterase inhibitors
	* nerve agents / nerve gases / CBR weapons
	* pharmacology main index
	* toxicology
	* parasympathetics

Organophosphate &amp; Carbamate Insecticide Poisoning:

Pathophysiology:

	* Both organophosphate &amp; carbamate insecticides are acetylcholinesterase inhibitors which are readily absorbed through intact skin or mucosa as well as from the GIT.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Jul 2025 22:51:57 +0000</pubDate>
        </item>
        <item>
            <title>Mx of psychostimulant toxicity from amphetamines and related substances</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odamphetamines</link>
            <description>Mx of psychostimulant toxicity from amphetamines and related substances

see also:

	* amphetamine (speed) and related substances - metamphetamine (ice), MDMA(Ecstasy), MDA (Adam), MDEA (Eve), cocaine (crack), PMA, PMMA, flakka, etc
	* toxicology
	* sympathomimetics

Clinical manifestations of psychostimulant toxicity

acute toxicity

cardiovascular

	* tachycardia, hypertension, arrhythmias, vasospasm, aortic dissection, acute coronary syndrome, hypotension (late), acute cardiomyopathy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 07:38:59 +0000</pubDate>
        </item>
        <item>
            <title>Anticonvulsant overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odanticonvulsants</link>
            <description>Anticonvulsant overdose

see also toxicology, anticonvulsants

see RCH guideline - anticonvulsant poisoning</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Sep 2008 11:26:06 +0000</pubDate>
        </item>
        <item>
            <title>Antihistamine overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odantihistamine</link>
            <description>Antihistamine overdose

see also toxicology, antihistamines

see RCH guidelines - antihistamine poisoning</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Sep 2008 11:29:01 +0000</pubDate>
        </item>
        <item>
            <title>baclofen overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odbaclofen</link>
            <description>baclofen overdose

see also:

	* toxicology

introduction

	* baclofen is a synthetic derivative of GABA and in Rx doses, mainly acts upon GABA-B receptors, inhibiting the release of the excitatory amino acids glutamate and aspartate
	* in overdoses &gt; 200mg in adults, this can result in significant CNS depression causing sedation and coma which may be profound and prolonged with hyporeflexia, hypotonia, fixed, dilated pupils, lasting 24-48hrs and thus admission to a ICU/HDU is generally needed</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 25 Sep 2015 00:42:51 +0000</pubDate>
        </item>
        <item>
            <title>Benzodiazepine overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odbenzodiazepines</link>
            <description>Benzodiazepine overdose

see also benzodiazepines, benzodiazepine antagonists eg. flumazenil, toxicology

see RCH guideline - benzodiazepine poisoning</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Sep 2008 11:31:21 +0000</pubDate>
        </item>
        <item>
            <title>beta adrenergic blocker overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odbetablocker</link>
            <description>beta adrenergic blocker overdose

see also:

	* beta blockers
	* toxicology
	* LITFL - massive propranolol overdose

general features of beta blockers in overdose:

	* more rapid onset of life-threatening features than with digoxin OD:
		* life-threatening CNS/CVS effects may occur within 30min of ingestion &amp; death by 80min</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 04 Jun 2022 04:54:39 +0000</pubDate>
        </item>
        <item>
            <title>calcium channel blocker overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odcalciumblockers</link>
            <description>calcium channel blocker overdose

see also:

	*  calcium channel blockers
	*   toxicology

general features of toxicity:

	* similar in many respects to beta blocker overdose:
	* selectivity is lost
	* toxicity mainly results from negative inotropy, chronotropy, dromotropy &amp; vasodilatation
		* =&gt; hypotension, bradycardia, AV block, sinus arrest, junctional rhythm, asystole</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Dec 2015 04:30:47 +0000</pubDate>
        </item>
        <item>
            <title>chloral hydrate overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odchloralhydrate</link>
            <description>chloral hydrate overdose

see also:

	* toxicology
	* LifeInTheFastLane - Australian case presentation of Mx of Chloral Hydrate overdose

introduction

	* chloral hydrate is a sedative hypnotic agent which acts via GABA receptors and is metabolised by RBC's to trichloroethanol within ~4 minutes, and then hours later is metabolised further to trichloroacetic acid.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 14 Aug 2011 05:01:40 +0000</pubDate>
        </item>
        <item>
            <title>Colchicine overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odcolchicine</link>
            <description>Colchicine overdose

see also colchicine, toxicology

Toxicity:

general features:

	* death from as little as 7mg, survival with ingestions as large as 350mg
	* survival usual with doses &lt; 0.5mg/kg (ie. low therapeutic index!!)
	* death almost certain with doses &gt; 0.8mg/kg</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 30 Sep 2008 11:10:16 +0000</pubDate>
        </item>
        <item>
            <title>digoxin toxicity</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=oddigoxin</link>
            <description>digoxin toxicity

see also: digoxin, pharmacology main index, cardiac arrhythmias

ref:  EMedicine article on digitalis toxicity

Probability of digoxin toxicity being the cause of the symptoms

	* bradycardia alone =&gt; 10% if serum digoxin 1.9nmol/L &amp; 50% if serum digoxin 3.2nmol/L
	* GI symptoms alone =&gt; 25% if serum digoxin 1.9nmol/L &amp; 60% if serum digoxin 3.2nmol/L</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Feb 2009 02:29:34 +0000</pubDate>
        </item>
        <item>
            <title>hydroflouric acid poisoning or burns</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odhydroflouricacid</link>
            <description>hydroflouric acid poisoning or burns

see also:

	* burns
	* &lt;https://www.health.gov.au/resources/publications/australian-clinical-guidelines-for-acute-exposures-to-chemical-agents-of-health-concern?language=en&gt;
	* &lt;https://www.rch.org.au/clinicalguide/guideline_index/Hydrofluoric_acid_exposure/&gt;
	* StatPearls 2023

introduction

	* hydrofluoric acid exposure can occur through oral, inhalation, ocular or dermal exposure. 
	* Industrial HF preparations may have concentrations of up to 100%. 
	* D…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 23 Mar 2023 00:41:23 +0000</pubDate>
        </item>
        <item>
            <title>hydrogen peroxide poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odhydrogen_peroxide</link>
            <description>hydrogen peroxide poisoning

introduction

	* hydrogen peroxide is an oxidising agent that is used in a number of household products, including general-purpose disinfectants, chlorine-free bleaches, fabric stain removers, contact lens disinfectants and hair dyes, and it is a component of some tooth whitening products.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 28 Jun 2013 23:34:28 +0000</pubDate>
        </item>
        <item>
            <title>hydrogen sulphide gas poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odhydrogen_sulphide</link>
            <description>hydrogen sulphide gas poisoning

see also:

	* toxicology

introduction

	* hydrogen sulphide is a colourless, highly toxic gas, and thankfully poisonings are rare
	* it may be produced in chemical reactions that are involved in rubber vulcanization, viscose rayon manufacturing, pesticide production and the action of acid drain cleaners with sulfur-containing sludge.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Jan 2018 01:16:50 +0000</pubDate>
        </item>
        <item>
            <title>iron poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odiron</link>
            <description>iron poisoning

see also toxicology, iron deficiency anaemia

see RCH guideline - iron poisoning</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Dec 2010 02:06:30 +0000</pubDate>
        </item>
        <item>
            <title>odontogenic sinusitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odontogenic_sinusitis</link>
            <description>odontogenic sinusitis

see also:

	* ears, nose and throat surgery (ENT)
	* sinusitis
	* acute dental pain / dental abscess
	* antibiotics

Introduction

	* infection of the sinuses is common and often becomes chronic 
	* most commonly, bilateral sinusitis is a complication of upper respiratory tract infections - see sinusitis
	* chronic unilateral maxillary sinusitis is very suggestive of an</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2024 06:53:40 +0000</pubDate>
        </item>
        <item>
            <title>heroin or other opiate overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odopiates</link>
            <description>heroin or other opiate overdose

see also:

	* opiate and opioid antagonists
	* opiates and opioids
	* methadone overdose

introduction

	* opiate overdose is an extremely common presentation to ED's - usually due to iv heroin OD or the newer more potent opiates such as fentanyl or nitazene but can also be iatrogenic in patients at risk of respiratory depression such as in the elderly, or those with COPD or obstructive sleep apnoea</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Jun 2023 00:26:12 +0000</pubDate>
        </item>
        <item>
            <title>paracetamol overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odparacetamol_single</link>
            <description>paracetamol overdose

see also:

	* toxicology
	* paracetamol (acetaminophen)
	* N-acetyle cysteine (Parvolex)
	* RCH guideline - paracetamol poisoning

introduction:

	* this paper is a brief summary of the MJA 2019 consensus guidelines on Mx of paracetamol overdose to assist in efficient care.
	* the far majority of paracetamol overdoses do not have any long term sequelae, however, some patients are at risk of developing potentially lethal hepatotoxicity over the succeeding few days due to a t…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Feb 2026 00:08:16 +0000</pubDate>
        </item>
        <item>
            <title>Phenothiazine overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odphenothiazines</link>
            <description>Phenothiazine overdose

see also anti-psychotic medications, toxicology

Phenothiazine overdose:

	* Thioridazine &amp; mesoridazine are the only anti-psychotics associated with single-drug fatal overdoses as these have quinidine-like actions &amp; thus can induce ventricular arrhythmias, management of these should be as for tricyclic antidepressants. Other anti-psychotics are rarely fatal on OD.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Sep 2008 05:10:27 +0000</pubDate>
        </item>
        <item>
            <title>salicylate poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odsalicylates</link>
            <description>salicylate poisoning

see also:

	* toxicology
	* Emedicine.com
	* RCH guideline - paediatric salicylate poisoning

epidemiology

	* salicylate (eg. aspirin (acetylsalicylic acid), teething gels) poisoning has steadily declined over the past 10-15 yrs in parallel with the declining use of aspirin particularly in children, and the use of child resistant packaging. However, parents should still be warned of the potentially lethal dangers of aspirin.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 Jun 2012 15:57:08 +0000</pubDate>
        </item>
        <item>
            <title>theophylline and methylxanthine poisonings and overdoses</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odtheophylline</link>
            <description>theophylline and methylxanthine poisonings and overdoses

see also:

	* toxicology
	* drug-induced seizures
	* methylxanthines eg. theophylline, caffeine
	* RCH guideline - paediatric theophylline poisoning</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2009 06:23:04 +0000</pubDate>
        </item>
        <item>
            <title>tricyclic antidepressant overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odtricyclics</link>
            <description>tricyclic antidepressant overdose

see also:

	* toxicology
	* tricyclic antidepressants
	* RCH guideline - tricyclic poisoning
	* LITFL - tricyclic OD
	* LITFL - ECG changes diagnostic of tricyclic OD

management:

	* these patients have a tendency to suddenly develop seizures, reduced conscious state, or, if widened QRS, VT or VF
	* consider activated charcoal 1g/kg unless altered conscious state (protect airway first by intubation and then give via NG tube)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 13 Aug 2014 00:12:39 +0000</pubDate>
        </item>
        <item>
            <title>Mx of excessive INR or bleeding on warfarin Rx</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=odwarfarin</link>
            <description>Mx of excessive INR or bleeding on warfarin Rx

see also:

	* anticoagulants
	* warfarin
	* INR
	* Western Health guidelines on Mx of bleeding on warfarin (pdf) - only available within WH intranet
	* Warfarin Reversal: consensus guidelines, on behalf of the Australasian Society of Thrombosis and Haemostasis (pdf)
	* WH Warfarin Reversal Guidelines Quick Guide (pdf) -only available within WH intranet
	* WH - Warfarin Reversal Consensus Guidelines full version (pdf) - only available within WH intr…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 11 May 2014 10:26:27 +0000</pubDate>
        </item>
        <item>
            <title>acute hydroxychloroquine or chloroquine overdose / toxicity (Plaquenil)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=od_hydroxychloroquine</link>
            <description>acute hydroxychloroquine or chloroquine overdose / toxicity (Plaquenil)

see also:

	* hydroxychloroquine (Plaquenil)

Introduction

	* hydroxychloroquine and chloroquine have relatively narrow therapeutic windows and acute toxicity is a risk, particularly for those who self-prescribe</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 26 Mar 2020 01:21:22 +0000</pubDate>
        </item>
        <item>
            <title>isoniazid overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=od_isoniazid</link>
            <description>isoniazid overdose

see also:

	* isoniazid
	* toxicology

introduction

	* isoniazid (INH) is a antibiotic medication used to Rx tuberculosis (TB)
	* isoniazid toxicity causes seizures usually within 1hr post-ingestion, but may occur 30min to 5hrs post-ingestion
	* ingestion of 80-150mg/kg is associated with severe toxicity and significant mortality unless treated</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Apr 2014 03:27:10 +0000</pubDate>
        </item>
        <item>
            <title>methadone overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=od_methadone</link>
            <description>methadone overdose

see also:

	* opiate antagonists
	* methadone
	* opiates and opioids

Introduction

	* methadone is a potentially lethal medication when taken in overdose, and its variable half-life and gradual onset, prolonged effects on respiratory depression which may persist for 48hrs or more can lead to delayed deaths even after 24hrs of naloxone infusion therapy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 02 Sep 2020 02:16:57 +0000</pubDate>
        </item>
        <item>
            <title>nitrate and nitrate toxicity / overdose</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=od_nitrates</link>
            <description>nitrate and nitrate toxicity / overdose

see also:

	* nitrates including GTN
	* Austin Poisons Centre guideline - Mx of methaemoglobinaemia

Introduction

	* nitrate or nitrate toxicity may be iatrogenic, accidental or intentional self harm
	* the prime toxicity is via production of methaemoglobinaemia

Mx of toxicity

	* see methaemoglobinaemia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 May 2020 06:12:53 +0000</pubDate>
        </item>
        <item>
            <title>oesophageal fistulae and aorto-oesophageal fistulae</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=oesophageal_fistulae</link>
            <description>oesophageal fistulae and aorto-oesophageal fistulae

see also:

	* upper GIT bleeding

Introduction

	* fistulae may form from the oesophagus to adjacent anatomic organs such as:
		*  aorta (aorto-oesophageal fistula)
		*  pericardium (oesophageal–pericardial fistula)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Jun 2020 13:20:46 +0000</pubDate>
        </item>
        <item>
            <title>oesophageal rupture or perforation including Boerhaave syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=oesophageal_rupture</link>
            <description>oesophageal rupture or perforation including Boerhaave syndrome

see also:

	* gastroenterology

Introduction

	* oesophageal rupture or perforation is a rare potentially life threatening condition
	* 

Aetiology

	* Boerhaave syndrome
		*  spontaneous rupture or perforation of oesophagus due to severe straining or vomiting</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 May 2024 06:03:28 +0000</pubDate>
        </item>
        <item>
            <title>oesophageal varices</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=oesophageal_varices</link>
            <description>oesophageal varices

see also:

	* upper GIT bleeding
	* cirrhosis
	* portal hypertension
	* AFTB Lectures - oesophageal varices (2016)

Introduction

	* oesophageal varices are primarily caused by portal hypertension which most commonly results from cirrhosis
	* these may cause significant and life threatening upper GIT bleeding

Epidemiology

	* 50% of patients with cirrhosis have varices</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Aug 2018 08:28:08 +0000</pubDate>
        </item>
        <item>
            <title>oesophagitis in adults</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=oesophagitis</link>
            <description>oesophagitis in adults

see also:

	* Dyspepsia
	* eosinophilic oesophagitis (EoE)
	* gastro-oesophageal reflux
	* oesophageal cancer
	* gastroenterology
	* the adult patient with chest pain in the ED

Introduction

	* oesophagitis is one of the most common conditions in adults

Classification of adult oesophagitis

	* reflux oesophagitis
		*  the most common subtype of 0esophagitis, is caused by the reflux of gastric contents into the oesophagus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 31 May 2024 13:33:13 +0000</pubDate>
        </item>
        <item>
            <title>oestrogens</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=oestrogens</link>
            <description>oestrogens

see also:

	* gynaecology
	* combined OCP
	* hormone replacement therapy (HRT)

introduction

	* mainly beta-oestradiol, but also oestrone &amp; oestriol, the latter being the almost totally impotent liver metabolite of the former two.
	* oestrogenic potencies:
		* oestradiol 12 x oestrone &amp; 80 x oestriol;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Jul 2016 13:38:49 +0000</pubDate>
        </item>
        <item>
            <title>olanzapine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=olanzapine</link>
            <description>olanzapine

see also:

	* managing violence or the aggressive patient in the ED
	* bipolar disorder
	* psychosis
	* schizophrenia
	* anti-psychotic medications

introduction

	* olanzapine is an atypical antipsychotic, antimanic and mood stabilising agent.
	* it is available in sublingual wafer form, tablets and as a parenteral injectable for im use, although recent studies suggest it can be used safely for iv dosing with 5mg doses in adults.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 24 Jul 2025 23:32:26 +0000</pubDate>
        </item>
        <item>
            <title>onchocerciasis / river blindness</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=onchocerciasis</link>
            <description>onchocerciasis / river blindness

see also:

	* parasites
	* the febrile returned traveller
	* wikipedia

introduction

	* onchocerciasis is caused by the nematode (roundworm) parasite Onchocerca volvulus
	* it is the world's second-leading infectious cause of blindness affecting some 270,000 of the 18 million people infected by it</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 05 Jan 2012 04:21:09 +0000</pubDate>
        </item>
        <item>
            <title>oncology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=oncology</link>
            <description>oncology

see also:

	* the immunocompromised patient in the ED
	* ionising radiation
	* radiation emergencies
	* acute tumour lysis syndrome
	* multiple myeloma
	* tissue growth disorders
	* neoplasia / cancer / tumours
	* neoplastic spread
	* chemotherapy for cancers
	* bone marrow transplant (BMT)
	* Western Health oncology / cancer services</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Jan 2020 09:51:10 +0000</pubDate>
        </item>
        <item>
            <title>tissue growth disorders</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=onc_growth_disorders</link>
            <description>tissue growth disorders

see also:

	* oncology
	* neoplasia / cancer / tumours
	* pathology

hypertrophy

	* increase in individual cell size due to a stimulus (eg. functional stress);
	* physiologic:
		* hormonal stimulation eg. uterus in pregnancy
		* increased workload eg. skeletal &amp; cardiac muscle</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 22 Oct 2009 06:45:13 +0000</pubDate>
        </item>
        <item>
            <title>ondansetron</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ondansetron</link>
            <description>ondansetron

see also:

	* metoclopramide (Maxolon)

	* high dose iv ondansetron may cause clinically significant QTc prolongation in some patients and iv doses for children on medications which cause prolonged QTc or have PH medical risk factors may cause potentially fatal arrhythmias</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 11 Aug 2017 01:19:43 +0000</pubDate>
        </item>
        <item>
            <title>ophthalmology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ophthalmology</link>
            <description>ophthalmology

	* eye injuries
		* welder flash burns - UV keratopathy (photo keratitis)
		* retrobulbar haemorrhage
		* chemical injuries and burns to the eyes
		* corneal abrasions

	* keratitis
	* the patient with acute blurred vision or visual loss / blindness
	* diplopia / double vision
	* conjunctivitis
	* acute atraumatic painful red eye(s)
	* glaucoma
	* uveitis
	* episcleritis
	* fundoscopy
	* optic neuritis
	* cataracts
	* local anaesthetic agents
	* Periorbital and orbital cellulitis
…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 30 Aug 2025 23:28:50 +0000</pubDate>
        </item>
        <item>
            <title>opiates and opioids</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=opiates</link>
            <description>opiates and opioids

	* Heroin
	* morphine
	* pethidine
	* codeine
	* fentanyl
	* oxycodone
	* tramadol
	* tapentadol
	* methadone
	* carfentanil - 100x more potent than fentanyl, used to tranquilize elephants, extremely dangerous to humans
	* pholcodine - antitussive cough medication withdrawn by TGA in Australia in 2023 as increases risk of anaphylaxis during general anaesthesia by 300x for the next 12 months after dosing.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 13 Aug 2024 02:05:10 +0000</pubDate>
        </item>
        <item>
            <title>opiate and opioid antagonists</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=opiate_antag</link>
            <description>opiate and opioid antagonists

see also:

	* heroin or other opiate overdose
	* opiates and opioids
	* opiate and opioid dependence
	* Addiction medicine - drug and alcohol - main index and links
	* avoid opiates and tramadol in back pain as there is evidence suggests they are of little benefit over non-steroidal anti-inflammatory drugs (NSAIDs) and do more harm, especially for chronic pain, instead consider a stat dose of corticosteroids such as 75mg prednisolone if acute disabling pain</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 09:02:18 +0000</pubDate>
        </item>
        <item>
            <title>Mx of opiate withdrawal</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=opiate_withdrawal</link>
            <description>Mx of opiate withdrawal

see also:

	* opiates and opioids

Mx in ED

	* DO NOT GIVE opioids if patient has taken naltrexone as it would require large doses to overcome the naltrexone and this will risk fatal overdosage
		* in this scenario, see Mx of severe acute opiate withdrawal due to inappropriate use of naltrexone

	* the greatest risk on discharge from hospital after withdrawal is the patient now having lower tolerance and much high risk of opiate overdose on use</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 Jun 2022 03:07:51 +0000</pubDate>
        </item>
        <item>
            <title>Mx of severe acute opiate withdrawal due to inappropriate use of naltrexone</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=opiate_withdrawal_naltrexone</link>
            <description>Mx of severe acute opiate withdrawal due to inappropriate use of naltrexone

see also:

	* opiate and opioid antagonists
	* opiates and opioids

introduction

	* naltrexone is a long acting opioid receptor antagonist
	* it should NOT be used in opiate-dependent persons within 7-10 days of last opiate dose otherwise there is a high risk of a severe, potentially life threatening acute opiate withdrawal reaction.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 May 2014 04:50:21 +0000</pubDate>
        </item>
        <item>
            <title>opiate and opioid dependence</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=opioid_dependence</link>
            <description>opiate and opioid dependence

see also:

	* Addiction medicine - drug and alcohol - main index and links
	* opiates and opioids
	*  opiate antagonists eg naloxone (Narcan), buprenorphine, naltrexone 
	* methadone
	* pain, analgesia and analgesics

Heroin use

	* comes as white or brown powder which is usually heated on a spoon and then injected or smoked
	* 10 points = 1 g 
	* most users use 1 point at a time
	* even 1 point a day is likely to lead to withdrawal symptoms on cessation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:45:19 +0000</pubDate>
        </item>
        <item>
            <title>optic neuritis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=optic_neuritis</link>
            <description>optic neuritis

see also:

	* ophthalmology
	* the patient with acute blurred vision or visual loss / blindness

Introduction

	* a demyelinating inflammation of the optic nerve that often occurs in association with multiple sclerosis (MS) and neuromyelitis optica (NMO)
	* women 2x more than men
	* 4-5 cases per 100,000 people per year in Scandinavia - maybe more frequent in temperate regions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 22 Aug 2023 04:38:13 +0000</pubDate>
        </item>
        <item>
            <title>the oral microbiome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=oral_microbiome</link>
            <description>the oral microbiome

see also:

	* the GIT microbiome

Introduction

	* the oral microbiome is an overlooked cause of disease and the importance of dental health has a preventive medicine measure is inadequately funded
	* it possesses the second-highest level of diversity after the gut microbiome, encompasses a wide array of bacterial genera and families</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 21 Sep 2025 13:02:39 +0000</pubDate>
        </item>
        <item>
            <title>Periorbital and orbital cellulitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=orbital_cellulitis</link>
            <description>Periorbital and orbital cellulitis

see also:

	*  cellulitis
	*  antibiotics
	*  perichondritis / ear/auricle/pinna cellulitis
	* RCH guideline - periorbital and orbital cellulitis

Introduction

	* periorbital (“preseptal”) cellulitis is superficial and does not extend deep to the orbital septum but may do so in which case it becomes orbital cellulitis
	* orbital cellulitis extends deep to the orbital septum and risks permanent eye damage, intracranial infection and sepsis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 08 Oct 2025 07:52:37 +0000</pubDate>
        </item>
        <item>
            <title>orthopaedics in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=orthopaedics</link>
            <description>orthopaedics in the ED

see also:

	* sports injuries
	* plaster application
	* Western Health Orthopaedics and Fractures


general orthopaedics

	* Phong Tran's Western Health orthopaedic website - principles of fracture management including describing fractures, fracture classification systems and trauma principles
	* bone physiology
	* pathologic processes involving bone
	* osteoporosis
	* kyphosis
	* scoliosis
	* Bier's block - iv regional anaesthesia for LAMPs

emergency department presenta…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 25 Sep 2023 08:16:09 +0000</pubDate>
        </item>
        <item>
            <title>obstructive sleep apnoea (OSA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=osa</link>
            <description>obstructive sleep apnoea (OSA)

see also:

	* obesity and weight management
	* noisy breathing
	* snoring
	* physiology of sleep

Introduction

	* characterized by loud snoring followed by periods of silence when breathing stops or nearly stops which usually occurs at least five times during every hour of sleep
	* affects 2-4% of adults</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 13 Nov 2025 10:10:52 +0000</pubDate>
        </item>
        <item>
            <title>osteoarthritis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=osteoarthritis</link>
            <description>osteoarthritis

see also:

	* arthritis - clinical patterns

introduction

	* a “degenerative” or inflammatory disorder of joints arising from the breakdown of articular (hyaline) cartilage
	* radiographic hand OA is present in approximately 40–60% of adults over age 55, while symptomatic hand OA affects about 13–26% of individuals in the same age group</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Mar 2026 12:54:47 +0000</pubDate>
        </item>
        <item>
            <title>osteomyelitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=osteomyelitis</link>
            <description>osteomyelitis

	* RCH guideline - osteomyelitis and septic arthritis
	* septic arthritis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 02 Mar 2014 12:56:48 +0000</pubDate>
        </item>
        <item>
            <title>osteonecrosis / avascular necrosis bone (AVN)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=osteonecrosis</link>
            <description>osteonecrosis / avascular necrosis bone (AVN)

see also:

	* orthopaedics in the ED
	* corticosteroids

Introduction

	* osteonecrosis / avascular necrosis bone (AVN) is usually a slowly progressive condition which results in significant morbidity
	* 90% of atraumatic cases are due to either</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 26 Oct 2021 01:15:42 +0000</pubDate>
        </item>
        <item>
            <title>osteoporosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=osteoporosis</link>
            <description>osteoporosis

see also

	* bone physiology
	* calcium
	* vitamin D
	* bisphosphonates
	* sacral insufficiency fracture (SIF) - osteoporotic fracture
	* MJA 2010 Position Statement - Treatment for osteoporosis in Australian residential aged care facilities: consensus recommendations for fracture prevention

introduction

	* in Australia, lifetime risk of osteoporosis in those over 50yrs age is 42% for women and 27% for men.
	* affects 2 million Australians
	* 20,000 hip fractures per year in Aust…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Mar 2026 21:15:30 +0000</pubDate>
        </item>
        <item>
            <title>otitis externa</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=otitis_externa</link>
            <description>otitis externa

see also:

	* otitis media
	* ears, nose and throat surgery (ENT)
	* RVEEH clinical practice guidelines:
		* Bacterial otitis externa (pdf)
		* Fungal otitis externa (pdf)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Oct 2018 03:31:57 +0000</pubDate>
        </item>
        <item>
            <title>otitis media</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=otitis_media</link>
            <description>otitis media

see also:

	* paediatric emergency medicine
	* otitis externa
	* ears, nose and throat surgery (ENT)
	* RCH guideline - acute otitis media
	* NSW NETS - otitis media (pdf)

Other references

	* RVEEH clinical practice guidelines
		* Acute Otitis Media (pdf)


MJA 2009 Supplement (free online)

	* MJA 2009: Natural history, definitions, risk factors and burden 
of otitis media
	* MJA 2009: Otitis media: viruses, bacteria, biofilms and vaccines
	* MJA 2009: Theories of otitis media p…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Oct 2018 03:34:24 +0000</pubDate>
        </item>
        <item>
            <title>drug induced ototoxicity</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ototoxicity</link>
            <description>drug induced ototoxicity

see also:

	* sensorineural hearing loss / deafness
	* ED Mx of vertigo and BPV

introduction

	* many drugs have the potential to cause ototoxicity and depending upon the drug and circumstances, it may be reversible or irreversible, and it may be primarily cochleotoxic (causing deafness) or, as with gentamicin, primarily vestibulotoxic.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 27 Sep 2013 08:23:56 +0000</pubDate>
        </item>
        <item>
            <title>ovarian cysts and other cysts in the adnexae</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ovarian_cysts</link>
            <description>ovarian cysts and other cysts in the adnexae

see also:

	* gynaecology
	* ovarian tumours
	* the patient with an adnexal mass
	* the patient with acute abdominal pain in the ED

functional ovarian cysts

follicular cysts

	* account for 20-50% of ovarian masses in post-menarchal women during the reproductive years
	* ruptured cysts may present as acute severe pelvic pain worse on movement +/- rebound tenderness. The pain usually decreases over 1-2 days.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Oct 2009 22:43:41 +0000</pubDate>
        </item>
        <item>
            <title>overactive bladders, urgency and urge incontinence</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=overactive_bladder</link>
            <description>overactive bladders, urgency and urge incontinence

see also:

	* urology

introduction

	* overactive bladder (OAB) is a troublesome condition resulting from detrusor overactivity which contracts inappropriately during bladder filling
	* it has a serious impact on quality of life</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Aug 2019 07:17:14 +0000</pubDate>
        </item>
        <item>
            <title>ovarian hyperstimulation syndrome (OHSS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ovhss</link>
            <description>ovarian hyperstimulation syndrome (OHSS)

see also:

Introduction

	* a complication of IVF therapies which although most cases are mild, can result in severe illness and generally lasts 1-2 weeks

Clinical features

mild OHSS

	* ovarian enlargement to 5-12cm</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Dec 2022 01:07:49 +0000</pubDate>
        </item>
        <item>
            <title>ovulation induction for IVF</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ovulation_induction</link>
            <description>ovulation induction for IVF

see also:

	* in-vitro fertilisation (IVF)

ovulation induction agents

clomiphene

	* Clomid or Seraphine
	* blocks the effects of oestrogens and causes the body to produce more follicle stimulating hormone

Human Menopausal Gonadotropin

	* hMG is derived from the urine of post-menopausal women</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 29 Jan 2014 01:19:39 +0000</pubDate>
        </item>
        <item>
            <title>oxycodone</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=oxycodone</link>
            <description>oxycodone

see also:

	* opiates and opioids
	* pain, analgesia and analgesics

introduction

	* has a higher bioavailability (up to 90%) when taken orally and is thus 1-2x as potent as oral morphine
	* although metabolised by CYP2D6 to oxymorphone, this has limited role in analgesia
	* perhaps a better choice for mod-severe pain than panadeine forte as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Apr 2014 02:54:09 +0000</pubDate>
        </item>
        <item>
            <title>oxygen</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=oxygen</link>
            <description>oxygen

see also:

	* medical gases
	* home oxygen
	* hypoxia
	* respiratory medicine
	* chronic obstructive pulmonary disease (COPD)

introduction

	* once it was thought you could never have too much oxygen, but it has become clear that excessive levels of oxygen can be detrimental, particularly to ischaemic tissues (eg. in acute myocardial infarction (AMI/STEMI/NSTEMI)) and to neonates</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 28 Mar 2020 05:12:25 +0000</pubDate>
        </item>
        <item>
            <title>oxytocin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=oxytocin</link>
            <description>oxytocin

see also:

	* ED Mx of 3rd stage of labour
	* ergometrine
	* &lt;https://en.wikipedia.org/wiki/Oxytocin&gt;

	* Oxytocin 10 units is the preferred uterotonic agent for active management of the third stage. It is preferred over other uterotonic drugs as it is effective straight away if administered IV, and within 2 to 4 minutes of administration if given IM.  It has minimal side effects and can be used in almost all women (except where there is a history of allergy to oxytocin or carbetocin).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 01 Jun 2020 11:09:03 +0000</pubDate>
        </item>
        <item>
            <title>paediatric emergency medicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=paediatrics</link>
            <description>paediatric emergency medicine

see also emergency medical retrieval services incl. PETS/NETS

External links

	* RCH clinical practice guidelines
	* Vic Paed Clinical Network 2017 promo video on RCH guideline resource 
	* RCH guideline - IV fluids
	* RCH paediatric emergency drug dose calculator
	* Don't Forget the Bubbles (DFTB) blog - FOAM for paeds
	* Cornell Uni Pediatric medical calculators
	* RCH antibiotic guidelines
	* DHS infectious diseases Blue Book
	* Vic. DHS infectious diseases sch…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:55:00 +0000</pubDate>
        </item>
        <item>
            <title>paediatric emergency resuscitation drugs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=paedresusdrugs</link>
            <description>paediatric emergency resuscitation drugs

see also paediatric emergency medicine, anaesthetics, cardiac arrhythmias

	* RCH paediatric emergency drug dose calculator
	* RCH guideline - resuscitation
	* RCH guideline - paediatric IV fluids
	* RCH paediatric drug doses
	* RCH antibiotic guidelines
	* Victorian Poisons Information Centre - Austin Hospital

Cardiac Arrest

	* RCH guideline - paediatric cardiac arrest algorithm
	* adrenaline / epinephrine 1:10000 iv 0.1 ml/kg
	* adrenaline / epinephr…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Mar 2009 00:21:28 +0000</pubDate>
        </item>
        <item>
            <title>sepsis /septicaemia in the paediatric patient</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=paed_sepsis</link>
            <description>sepsis /septicaemia in the paediatric patient

see also:

	*  paediatric emergency medicine
	*  febrile convulsions
	*  antibiotics
	*  meningitis
	*  pneumonia
	*  urinary tract infections (UTIs) / cystitis
	*  osteomyelitis
	*  septic arthritis
	*  infectious diseases
	*  fever - the febrile response to infections
	*  the febrile child
	*  sepsis / septicaemia
	* RCH guideline - febrile child &lt; 3yrs old
	* RCH guideline - illness in the returned traveler
	* RCH guideline - febrile neutropenia
…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 06 Jul 2017 22:02:59 +0000</pubDate>
        </item>
        <item>
            <title>Recognition of the sick child</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=paed_sick</link>
            <description>Recognition of the sick child

see paediatric emergency medicine, meningitis, septic shock

	* NSW NETS Recognition of the sick child (pdf)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 04:17:28 +0000</pubDate>
        </item>
        <item>
            <title>Platelet activating factor</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=paf</link>
            <description>Platelet activating factor

see also eicosanoids including prostaglandins

Introduction:

	* A soluble substance demonstrated to be released from leukocytes which caused platelet aggreg. (1971), which was confirmed &amp; named PAF;
	* Also at this time an antiHT polar renal lipid (APRL) produced by interstitial cells of renal medulla was described, &amp; this was concluded to be identical to PAF in 1979 &amp; was then also synthesised &amp; shown to be AGEPC - a phospholipid.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Sep 2008 14:18:35 +0000</pubDate>
        </item>
        <item>
            <title>Mx of acute pain in drug dependent patients</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=painmx_drug_dependent</link>
            <description>Mx of acute pain in drug dependent patients

see also pain, analgesia and analgesics, opiates and opioids, alcohol dependency, drug dependency

assessing acute pain in these patients

	* opiate Rx for pain relief may require modification in opiate-dependent patients but there is no cross-tolerance between opioids and most other drugs of abuse (eg.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Oct 2025 00:42:06 +0000</pubDate>
        </item>
        <item>
            <title>palliative care</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=palliative_care</link>
            <description>palliative care

see also:

	* end of life care
	* neoplasia / cancer / tumours
	* NSW College of Emergency Nursing - End of Life guidelines (pdf)
	* NSW Govt - End of Life Care and decision making guidelines
	* Emedicine - the palliative care patient in the acute setting of ED
	* Safer Care Victoria - Checklist for care plan for preparing patient to die at home
	* Western Health nursing home patient prescribing process (intranet only):
			* tips:
				* ALL patients returning to the RACF from ED…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:37:38 +0000</pubDate>
        </item>
        <item>
            <title>palpitations</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=palpitations</link>
            <description>palpitations

see also:

	* cardiac arrhythmias
	* cardiology

introduction

	* palpitations are a common symptom in the ED population
	* in the younger adult in particular, they are most commonly related to anxiety/stress but there are important conditions to consider such as:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 28 Jan 2016 02:42:53 +0000</pubDate>
        </item>
        <item>
            <title>polyarteritis nodosa (PAN)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pan</link>
            <description>polyarteritis nodosa (PAN)

see also:

	* vasculitis

introduction

	* rare disease
	* incidence of about 3-4.5 cases per 100,000 population annually
	* males 2x females
	* esp. ages 45-65yrs
	* systemic vasculitis involving medium to small arteries 
	* most commonly affects skin, joints, peripheral nerves, the gut, and the kidney</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 14 Aug 2013 11:55:26 +0000</pubDate>
        </item>
        <item>
            <title>pancreatitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pancreatitis</link>
            <description>pancreatitis

see also:

	*  chronic pancreatitis; 
	*  general surgery

aetiology or contributing factors:

	* alcohol abuse - esp. males 35-45yrs
	* cholelithiasis (gallstones) - esp. females &gt; 40yrs
	* acute severe hypertriglyceridaemia (SHTG)
	* others (&lt;10%):
		* trauma - penetrating or blunt
		* pregnancy - any trimester, post-partum
		* post-ERCP
		* hypercalcaemia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 11 Jul 2025 06:40:17 +0000</pubDate>
        </item>
        <item>
            <title>chronic pancreatitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pancreatitis_chronic</link>
            <description>chronic pancreatitis

see also:

	*  pancreatitis
	*  pancreatic cancer

epidemiology:

	* 70-80% of cases are due to alcohol abuse, most of the remaining are idiopathic
	* other causes:
		* malnutrition
		* hyperPTH
		* cystic fibrosis
		* trauma
		* hereditary pancreatitis
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 05 Oct 2014 22:41:22 +0000</pubDate>
        </item>
        <item>
            <title>pandemics - influenza, coronavirus, Ebola</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pandemics</link>
            <description>pandemics - influenza, coronavirus, Ebola

see also:

	* viruses
	* influenza
	* coronaviridae / corona viruses (CoV)
	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* pandemic preparation
	* pandemic community lock down ramifications
	* pandemic epidemiology
	* Cell Aug 2020: Fauci et al. Emerging pandemics

Introduction

	* a pandemic is an infectious disease outbreak affecting each of the populated continents
	* these are generally caused by highly infective viruses
	* two contagion factors…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 28 Sep 2025 23:27:38 +0000</pubDate>
        </item>
        <item>
            <title>pandemic epidemiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pandemic_epidemiology</link>
            <description>pandemic epidemiology

see also:

	* pandemics - influenza, coronavirus, Ebola
	* epidemiology
	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* Covid-19 modeling for Victoria
	* 2009 Infectious Disease Modelling: Estimating epidemic exponential growth rate and basic reproduction number
	* Modeling  COVID-19  epidemics  in  an  Excel  spreadsheet:  Democratizing the access to first-hand accurate predictions of epidemic outbreaks

Introduction

	* pandemics spread by contagions generally follow…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Sep 2021 09:35:58 +0000</pubDate>
        </item>
        <item>
            <title>pandemic community lock down ramifications</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pandemic_lockdown</link>
            <description>pandemic community lock down ramifications

see also:

	* viruses
	* influenza
	* coronaviridae / corona viruses (CoV)
	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* pandemic preparation
	* pandemics - influenza, coronavirus, Ebola
	* pandemic transmission mitigation through public health measures

Introduction

	* locking down social contact events by banning the community from leaving their homes for a number of weeks or months may be necessary to control pandemics but doing so is likely …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 12 Sep 2020 00:38:57 +0000</pubDate>
        </item>
        <item>
            <title>pandemic transmission mitigation through public health measures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pandemic_mitigation</link>
            <description>pandemic transmission mitigation through public health measures

see also:

	* viruses
	* influenza
	* coronaviridae / corona viruses (CoV)
	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* pandemic preparation
	* pandemics - influenza, coronavirus, Ebola
	* pandemic community lock down ramifications

Introduction

	* each pandemic pathogen has its own transmission and disease characteristics which will have a significant determination of optimum public health planning measures to attempt to m…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Sep 2020 01:43:00 +0000</pubDate>
        </item>
        <item>
            <title>pandemic preparation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pandemic_preparation</link>
            <description>pandemic preparation

see also:

	* viruses
	* influenza
	* coronaviridae / corona viruses (CoV)
	* COVID-19 coronavirus (2019-nCoV / SARS-CoV-2)
	* pandemics - influenza, coronavirus, Ebola
	* pandemic community lock down ramifications

Introduction

	* most countries will have the good fortune to have several weeks or even months to prepare for a pandemic once a threatening outbreak has occurred.
	* this period is critical to act upon to ensure adequate preparation based upon the known feature…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 27 Mar 2020 22:11:30 +0000</pubDate>
        </item>
        <item>
            <title>Reproduction Ratio (RO)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pandemic_ro</link>
            <description>Reproduction Ratio (RO)

see also:

	* pandemic epidemiology

Introduction

	* a measure of contagiousness
	* RO = the number of secondary infections each infected individual produces
	* this will vary with:
		*  the method by which it is estimated
		*  The rate of contact between individuals in the host population</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 18 Aug 2020 08:30:11 +0000</pubDate>
        </item>
        <item>
            <title>paracetamol (acetaminophen)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=paracetamol</link>
            <description>paracetamol (acetaminophen)

see also:

	*  pain, analgesia and analgesics
	*  paracetamol overdose

introduction:

	* an antipyretic analgesic agent also known as acetaminophen in the USA
	* 1st synthesised in 1877
	* extensive use commenced around 1947, initially as prescription only in USA
	* OTC status gained in 1960 in USA</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 17 May 2025 10:35:14 +0000</pubDate>
        </item>
        <item>
            <title>paraphimosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=paraphimosis</link>
            <description>paraphimosis

	* AAFP - paraphimosis

Mx of paraphimosis by reduction in ED

analgesia

	* consider:
		* topical local anaesthesia such as EMLA cream or 2% lignocaine gel
		* inhalational anaesthesia such as nitrous oxide
		* analgesics adjuncts such as oxycodone


reduce the oedema</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 22 Mar 2014 01:54:49 +0000</pubDate>
        </item>
        <item>
            <title>parasites</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=parasites</link>
            <description>parasites

see also:

	* microbiology
	* zoonoses
	* Antihelminths
	* the febrile returned traveller
	* could some helminths be good for you?

classification of parasites

protozoa:

	* NB. unicellular or acellular animals (eucaryotic);
	* sarcomastigophora (motile elements)
		* amoebae (pseudopods)
			* Entamoeba (anaerobe) - causes amoebiasis 
			* Naegleria (aerobe) - may cause meningitis from thermal baths</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 20 Dec 2025 09:39:30 +0000</pubDate>
        </item>
        <item>
            <title>parasympathetics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=parasympathetics</link>
            <description>parasympathetics

see also pharmacology main index, anti-muscarinic anticholinergic agents

Cholinergic effects of muscarinic receptors:

Muscarinic M1 receptor actions:

	* CNS:
		* ? motion sickness; Parkinsonian tremor &amp; extrapyr.;
		* ? memory function; EEG inc. voltage &amp; freq. alpha-rhythm;
			* =&gt; cortical arousal;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Nov 2009 13:45:00 +0000</pubDate>
        </item>
        <item>
            <title>paratyphoid enteric fever</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=paratyphoid</link>
            <description>paratyphoid enteric fever

see also:

	* Salmonella
	* Salmonella typhi (typhoid enteric fever)
	* the febrile returned traveller

introduction

	* there are three serovars of the species of S. enterica that cause paratyphoid: S. Paratyphi A, S. Paratyphi B (S. schottmuelleri and S. pullorum), and S. Paratyphi C (S. hirschfeldii).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Jan 2012 01:37:10 +0000</pubDate>
        </item>
        <item>
            <title>parechovirus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=parechovirus</link>
            <description>parechovirus

see also:

	* viruses
	* Neonates
	* wikipedia
	* NSW Govt factsheet for parents
	* NSW Govt factsheet for ED clinicians (pdf)
	* Vic. Better Health Channel factsheet

introduction

	* a group of small RNA viruses belonging to the family Picornaviridae
	* some were initially classed as echoviruses until this genus was recognized in 1996
	* human parechovirus (HPeV):
		* currently there are 6 types and 15 genotypes recognised</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Dec 2015 01:03:10 +0000</pubDate>
        </item>
        <item>
            <title>parecoxib</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=parecoxib</link>
            <description>parecoxib

see also:

	* non-steroidal anti-inflammatory drugs (NSAIDs)
	* ketorolac
	* pain, analgesia and analgesics

Introduction

	* an injectable pro-drug form of the COX2 selective inhibitor, valdecoxib.
	* the first parenteral COX-2 selective inhibitor available for clinical use in pain management
	* onset of action after IM / IV dose is 7-13 minutes with analgesia commencing 23-39 minutes and peaking at under 2 hours</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 31 May 2025 03:59:13 +0000</pubDate>
        </item>
        <item>
            <title>Parkinson's disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=parkinsons</link>
            <description>Parkinson's disease

see also:

	* dementia

Introduction

	* slowly progressive degenerative disorder of the CNS mainly starting in those aged over 60yrs (when it occurs before age 50yrs it is called early-onset PD)
	* motor impairments (“parkinsonism”) arise from the death of cells in the substantia nigra (in the basal ganglia within the midbrain) leading to a dopamine deficit.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Mar 2026 22:38:55 +0000</pubDate>
        </item>
        <item>
            <title>parotitis and parotid swellings</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=parotitis</link>
            <description>parotitis and parotid swellings

see also:

	* mumps

introduction

	* acute unilateral parotitis is usually due to an obstruction stone or acute bacterial parotitis
	* acute bilateral parotitis is usually due to mumps
	* alcoholism, sarcoidosis or HIV may cause chronic bilateral parotidomegaly</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 15 Oct 2025 05:30:01 +0000</pubDate>
        </item>
        <item>
            <title>Parvimonas infections</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=parvimonas</link>
            <description>Parvimonas infections

see also:

	* clinically important bacteria

Introduction

	* Catalase negative obligate anaerobic Gram-positive cocci 
	* Parvimonas micra was initially classified as Peptostreptococcus micros but re-classified within the Parvimonas genus in 2006
	* a known commensal of the human oral cavity and gastrointestinal tract.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Jun 2020 06:13:56 +0000</pubDate>
        </item>
        <item>
            <title>dislocated patella</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=patella_dislocation</link>
            <description>dislocated patella

see also:

	* dislocation of the knee joint
	* the acutely injured knee in ED

introduction

	* dislocated patella is a very common ED presentation in the adolescent and young adult in particular.
	* classically they present by ambulance with it still dislocated and holding a Penthrane analgiser stick.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Nov 2011 02:12:10 +0000</pubDate>
        </item>
        <item>
            <title>patello-femoral anterior knee pain</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=patellofemoral_pain</link>
            <description>patello-femoral anterior knee pain

see also:

	* knee pain
	* &lt;http://www.physioworks.com.au/injuries-conditions-1/patellofemoral-kneecap-pain-syndrome&gt;

Introduction

	* anterior knee pain is the most common type of knee pains referred to orthopaedic clinics
	* most cases are due to mechanical-induced pain within the patello-femoral joint due to overuse or overload, particularly if one embarks on a new activity that involves flexed knees such as walking or running up or down stairs, or, squatt…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Dec 2016 05:04:03 +0000</pubDate>
        </item>
        <item>
            <title>pathology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pathology</link>
            <description>pathology

	*  Pathology handbook – Available on CIS and the intranet
	*  Medicare Benefits Schedule 
	*  Royal College of Pathologists Australasia 
	* Melbourne Pathology Providers
	* microbiology
	* haematology
		* anaemia
		* iron
		* blood_groups
		* blood product transfusions
		* C reactive protein (CRP)
		* erythrocyte sedimentation rate (ESR)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Oct 2025 00:46:18 +0000</pubDate>
        </item>
        <item>
            <title>pathology tests - urea and creatinine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pa_ureacrn</link>
            <description>pathology tests - urea and creatinine

see also:

	* pathology
	* renal medicine (nephrology)
	* acute kidney injury (AKI) / acute renal failure (ARF)
	* chronic renal failure

urea

	* NH2CONH2
	* MW 60.1 =&gt; 1mmol/L = 60mg/L = 6mg/dL BUT measured urea is actually “blood urea nitrogen” so as there are 2 atoms of nitrogen per urea molecule and atomic weight of N is 14, the</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 11 Jul 2023 14:34:43 +0000</pubDate>
        </item>
        <item>
            <title>urinalysis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pa_urinalysis</link>
            <description>urinalysis

see also:

	* renal medicine (nephrology)
	* urinary tract infections (UTIs) / cystitis

heme

	* detects both free Hb (or myoglobin) and Hb within RBCs, although is more sensitive for the former.
	* normal individuals pass up to 1 million RBC's/24hrs in their urine which equates to &lt;= 5RBC's/hpf.
	* as little as 1ml of blood per litre urine may cause grossly appreciable haematuria</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 02 Jan 2014 05:03:06 +0000</pubDate>
        </item>
        <item>
            <title>polycystic ovary syndrome (PCOS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pcos</link>
            <description>polycystic ovary syndrome (PCOS)

see also:

	* gynaecology
	* androgens and androgenic effects
	* New Australian guidelines for PCOS 2011

history:

	* hyperandrogenism &amp; insulin were linked as early as 1921 when Achard &amp; Thiers published their classic description of bearded women with diabetes.
	* polycystic ovary syndrome 1st described in 1935 &amp; called Stein-Leventhal syndrome</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Feb 2026 02:51:28 +0000</pubDate>
        </item>
        <item>
            <title>Pneumocystis (carinii) jirovecii pneumonia (PCP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pcp</link>
            <description>Pneumocystis (carinii) jirovecii pneumonia (PCP)

see also:

	* AIDS

introduction

	* Pneumocystis jirovecii is a yeast-like fungus which is specifically pathogenic to humans and is commonly found in the lungs of normal humans.
	* &gt; 75% of children are seropositive by the age of 4.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 18 Sep 2012 08:10:44 +0000</pubDate>
        </item>
        <item>
            <title>Platelet-derived growth factor (PDGF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pdgf</link>
            <description>Platelet-derived growth factor (PDGF)

see also:

	* cytokines
	* fibroblast growth factors (FGF)

Introduction

	* a growth factor that regulates cell growth and division, particularly in new blood vessel formation and the proliferation of mesenchymal cells such as fibroblasts, osteoblasts, tenocytes, vascular smooth muscle cells and mesenchymal stem cells as well as chemotaxis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Aug 2025 06:34:46 +0000</pubDate>
        </item>
        <item>
            <title>pulmonary embolism (PE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pe</link>
            <description>pulmonary embolism (PE)

see also: EMedicine.com - PE

	* Ix of suspected pulmonary embolism (PE)
	* Mx of PE (Pulmonary Embolism)
	* Mx of suspected or actual DVT (Deep Vein Thrombosis)
	* historical perspectives of PE
	* anticoagulants
	* pulmonary vein thrombosis (PVT)

Introduction

	* thrombotic pulmonary embolism occurs from dislodgment of a thrombus in a systemic vein - usually a deep vein of the legs (DVT) - which then passes through the RA an RV into the pulmonary artery where it may we…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2026 03:33:18 +0000</pubDate>
        </item>
        <item>
            <title>pectus excavatum</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pectus_excavatum</link>
            <description>pectus excavatum

see also:

	* postural orthostatic tachycardia syndrome (POTS)

Introduction

	* a relatively common anterior chest wall deformity which is mostly asymptomatic but in some can cause reduced venous return / RV outflow obstruction issues with may result in a clinical picture similar to</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 29 Jun 2025 01:41:17 +0000</pubDate>
        </item>
        <item>
            <title>penicillins</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=penicillins</link>
            <description>penicillins

see also:

	* antibiotics

introduction

	* penicillins belong to the group of antibiotics (including cephalosporins) which act upon the beta lactam ring and thus compromise the bacterial cell wall in a bactericidal manner
	* penicillins act via binding to penicillin-binding proteins on the bacterial cell wall</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 02 Apr 2017 23:07:23 +0000</pubDate>
        </item>
        <item>
            <title>diseases and injuries of the penis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=penile_conditions</link>
            <description>diseases and injuries of the penis

see also:

	* acute scrotal pain or swelling
	* torsion of testes
	* epididymo-orchitis
	* penile trauma / fractured penis
	* scrotal infusion with saline
	* priapism
	* paraphimosis

Introduction

	* acute penile conditions are fairly common presentations to the ED and the initial triage may be quite inaccurate due to patient embarrassment

Penile trauma including fractured penis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 03 Aug 2025 09:34:16 +0000</pubDate>
        </item>
        <item>
            <title>penile trauma / fractured penis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=penile_trauma</link>
            <description>penile trauma / fractured penis

see also:

	* urology
	* Trends in Urology Gynaecology &amp; Sexual Health September/October 2007: Penile fracture: diagnosis and management

Introduction

	* most blunt penile injuries can be managed conservatively, however, the main concerns are
		*  a fractured penis - rupture of the sheath around the erectile cylinder of the penis
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 09 Jan 2025 10:02:49 +0000</pubDate>
        </item>
        <item>
            <title>peptic ulcer disease (PUD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=peptic_ulcer</link>
            <description>peptic ulcer disease (PUD)

see also:

	* epigastric pain
	*  Dyspepsia
	* EMedicine

introduction

	* Peptic ulcers are defects in the gastric or duodenal mucosa that extend through the muscularis mucosa.
	* Western society has a 10% lifetime prevalence of developing PUD.
	* Under normal conditions, a physiologic balance exists between peptic acid secretion and gastroduodenal mucosal defense. Mucosal injury and, thus, peptic ulcer occur when the balance between the aggressive factors and the de…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Oct 2025 00:46:55 +0000</pubDate>
        </item>
        <item>
            <title>perforated viscus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=perforated_viscus</link>
            <description>perforated viscus

see also:

	* the patient with acute abdominal pain in the ED

introduction

	* this refers to perforation of the gastro-intestinal tract
		* free perforation occurs when GIT contents spill freely into the abdominal cavity, causing diffuse peritonitis
		* contained perforation occurs when a full-thickness hole is created but free spillage is prevented because contiguous organs wall off the area (eg. a penetrating DU walled off by the pancreas)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Feb 2026 01:56:11 +0000</pubDate>
        </item>
        <item>
            <title>perianal abscess</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=perianal_abscess</link>
            <description>perianal abscess

see also:

	* ano-rectal pain
	* perirectal abscess
	* skin abscesses
	* labial abscess / Bartholins abscess
	* inflammatory bowel disease (IBD)
	* hidradenitis suppurativa

	* BEWARE: severe pain but no local signs may be due to other anorectal sites such as an intersphincteric abscess!

introduction

	* perianal abscesses are abscesses in the soft tissue surrounding the anal canal arising from the anal crypts, initially forming in the intersphincteric space, and are often ass…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 26 Jun 2019 07:21:41 +0000</pubDate>
        </item>
        <item>
            <title>pericardiocentesis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pericardiocentesis</link>
            <description>pericardiocentesis

see also:

	* cardiac tamponade
	* LITFL - pericardiocentesis

introduction

	* therapeutic pericardiocentesis is an emergency procedure to prevent death in a patient with suspected cardiac tamponade
	* diagnostic pericardiocentesis is often used to elicit the cause of patient with pericarditis with an effusion which is not settling with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 19 Jul 2013 05:48:15 +0000</pubDate>
        </item>
        <item>
            <title>pericarditis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pericarditis</link>
            <description>pericarditis

see also:

	* the adult patient with chest pain in the ED
	* myocarditis
	* Paient UK information sheet on pericarditis
	* 2025 ESC Guidelines for the management of myocarditis and pericarditis: Developed by the task force for the management of myocarditis and pericarditis of the European Society of Cardiology (ESC)

introduction

	* acute “viral”/“idiopathic” pericarditis has generally a brief and benign course after empiric treatment by aspirin (acetylsalicylic acid) or non-stero…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 17 Oct 2025 22:30:00 +0000</pubDate>
        </item>
        <item>
            <title>constrictive pericarditis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pericarditis_constrictive</link>
            <description>constrictive pericarditis

see also:

	* pericarditis
	* cardiac tamponade

introduction

	* scarring and consequent loss of the normal elasticity of the pericardial sac results in impaired ability of the heart to expand and fill with blood, this is termed constrictive pericarditis and needs to be differentiated from:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 19 Jul 2013 06:05:01 +0000</pubDate>
        </item>
        <item>
            <title>perichondritis / ear/auricle/pinna cellulitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=perichondritis</link>
            <description>perichondritis / ear/auricle/pinna cellulitis

see also:

	*  cellulitis
	*  antibiotics

Introduction

	* perichondritis is an infection of the tissue covering the cartilage of the outer ear, also known as the auricle or pinna. 
	* commonly caused by trauma, such as high ear cartilage piercing, burns, cuts, or insect bites.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 19 Feb 2024 02:35:13 +0000</pubDate>
        </item>
        <item>
            <title>periodontitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=periodontitis</link>
            <description>periodontitis

see also:

	* dental
	* dental caries
	* gingivitis
	* acute dental pain / dental abscess
	* odontogenic sinusitis

Introduction

	* periodontitis is inflammation in the tissues around the teeth and can cause “getting long in the tooth” due to gum recession and subsequent dental loss
	* Vincent's gingivitis - fusospirochaetal necrotising gingivitis may progress to necrotising periodontitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Mar 2026 07:31:01 +0000</pubDate>
        </item>
        <item>
            <title>perirectal abscess</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=perirectal_abscess</link>
            <description>perirectal abscess

see also:

	* ano-rectal pain
	* perianal abscess

Introduction

	* deep abscesses adjacent to the rectum

Types

ischio-rectal abscess

	*  deep abscess within fat of ischiorectal fossa 
	*  can track to opposite side to form a horseshoe-shaped track

submucous abscess</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2026 05:29:36 +0000</pubDate>
        </item>
        <item>
            <title>peritonitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=peritonitis</link>
            <description>peritonitis

see also:

	* the patient with acute abdominal pain in the ED

Introduction

	* peritonitis is a life threatening inflammation within the peritoneal fluid - usually due to bacterial sepsis
	* it may be spontaneous as in spontaneous bacterial peritonitis (SBP), or secondary to either inflammation of an intra-abdominal organ or following a penetrating wound</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Apr 2018 08:53:15 +0000</pubDate>
        </item>
        <item>
            <title>personality disorders</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=personality_disorders</link>
            <description>personality disorders

see also:

	* psychiatry and mental health
	* obsessive compulsive personality disorder (anankastic PD)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Oct 2015 12:36:58 +0000</pubDate>
        </item>
        <item>
            <title>pertussis (whooping cough)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pertussis</link>
            <description>pertussis (whooping cough)

see also The child with a cough, clinically important bacteria, antibiotics, bronchiectasis, the persistent cough

	* RCH guideline - pertussis
	* Australian Prescriber April 2009 - Managing pertussis in adults plus antibiotic prophylaxis for high risk contacts
	* Pertussis Information for GPs and other Health Care Providers on Clinical and Public Health Management (Western Australia - March 2010)

introduction

	* pertussis is caused by a bacteria Bordetella pertussi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Feb 2026 02:06:32 +0000</pubDate>
        </item>
        <item>
            <title>pethidine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pethidine</link>
            <description>pethidine

see also opiates and opioids, pain, analgesia and analgesics

Pethidine is no longer recommended for primary care analgesia as:

	*  shorter acting opioid analgesic than morphine
	*  half-lives of pethidine &amp; its active metabolite norpethidine, exceed duration of analgesia:
		*  repeated doses to obtain satisfactory analgesia results in accumulation of norpethidine, increasing risk of toxicity, esp. if renal impairment:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 May 2014 02:12:21 +0000</pubDate>
        </item>
        <item>
            <title>HOPPE score for outpatient Mx of PE</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pe_hoppe</link>
            <description>HOPPE score for outpatient Mx of PE

see also:

	* ED Mx of pulmonary embolism (PE)
	* PESI score for severity of PE
	* Am J Cardiol. 2017 Derivation and Validation of a Novel Prediction Model to Identify Low-Risk Patients With Acute Pulmonary Embolism.
	* &lt;https://www.jwatch.org/na44820/2017/09/14/prognosis-wars-new-hoppe-identify-low-risk-pulmonary&gt;
	* &lt;http://www.browncoatnation.com/deepdive/emim-sessions/hoppe-low-risk-pe/&gt;

Introduction

	* the HOPPE score is based on an Indian study publis…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Oct 2018 05:33:43 +0000</pubDate>
        </item>
        <item>
            <title>ED Mx of pulmonary embolism (PE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pe_mx</link>
            <description>ED Mx of pulmonary embolism (PE)

see also:

	* epidemiology, pathology and clinical features of PE
	* Ix of suspected pulmonary embolism (PE)
	* Western Health Massive PE and Thrombolysis protocol - intranet only

	* the following has NOT yet been updated as per the AHA 2026 new paradigm of classification and Mx of PE
		*  see AHA 2026: 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American Co…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Mar 2026 04:59:29 +0000</pubDate>
        </item>
        <item>
            <title>template to assist in the discharge documentation of suspected PE SSU admits</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pe_notation</link>
            <description>template to assist in the discharge documentation of suspected PE SSU admits

see also:

	* the adult patient with chest pain in the ED
	* Ix of suspected pulmonary embolism (PE)
	* Western Health ED: pain medications instruction sheet (pdf)
	* Western Health ED: adult chest pain discharge instruction sheet (pdf)

example notations to copy and paste

No definitive cause for this patient's chest pain was found at this presentation. In particular, there was no evidence to support diagnoses such as…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Apr 2015 07:16:32 +0000</pubDate>
        </item>
        <item>
            <title>PESI score for severity of PE</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pe_pesi</link>
            <description>PESI score for severity of PE

see also:

	* ED Mx of pulmonary embolism (PE)
	* HOPPE score for outpatient Mx of PE
	* American Journal of Respiratory and Critical Care Medicine 2005 Derivation and Validation of a Prognostic Model for Pulmonary Embolism 
	* Arch Intern Med. 2006 A prediction rule to identify low-risk patients with pulmonary embolism.

Introduction

	* a severity score for pulmonary embolism (PE) developed in 2005 based upon 15,531 inpatient discharges with pulmonary embolism fr…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Oct 2018 07:06:03 +0000</pubDate>
        </item>
        <item>
            <title>Wells scoring for pre-test probability of PE</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pe_wellsscore</link>
            <description>Wells scoring for pre-test probability of PE

see also Ix of suspected PE

	* MDCalc online calculator
	* determine if any risk factors present: (as per Wells 1998)
		* surgery within 12wks
		* immobilisation (complete bed rest) for 3 or more days in 4wks prior
		* previous DVT or objectively diagnosed PE</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Apr 2015 00:42:00 +0000</pubDate>
        </item>
        <item>
            <title>platelet factor 4 antibody thrombotic and thrombocytopenia syndromes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pf4abs</link>
            <description>platelet factor 4 antibody thrombotic and thrombocytopenia syndromes

see also:

	* coagulation pathways
	* thrombosis
	* thrombocytopenia
	* thrombosis with thrombocytopenia syndrome (TTS / VITT / VIPIT)
	* immune heparin-induced thrombocytopenia (HITS)

Introduction

	* antibodies against platelet factor 4 can cause life threatening thrombosis and [thrombocytopenia]]

Aetiology

	* immune heparin-induced thrombocytopenia (HITS)
	* adenovirus-induced antibodies against PF4</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 12 Aug 2023 12:44:03 +0000</pubDate>
        </item>
        <item>
            <title>Perfluoroalkyl and polyfluoroalkyl substances (PFAS) including PFOA, PFOS, GenX, Teflon</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pfas_pfoa</link>
            <description>Perfluoroalkyl and polyfluoroalkyl substances (PFAS) including PFOA, PFOS, GenX, Teflon

see also:

	* toxinology
	* phthalates
	* bisphenols (Bisphenol A (BPA), etc)
	* US EPA basic information on PFAS
	* NSW Health advisory
	* &lt;https://www.pfas.gov.au/about-pfas/affects&gt;
	* July 2020: A Probabilistic Approach to Evaluate the Risk of Decreased Total Triiodothyronine Hormone Levels following Chronic Exposure to PFOS and PFHxS via Contaminated Drinking Water
	* Youtube - a doco on the history of …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Apr 2026 00:54:29 +0000</pubDate>
        </item>
        <item>
            <title>phaeochromocytoma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=phaeochromocytoma</link>
            <description>phaeochromocytoma

see also:

	* catecholamines and sympathomimetics
	* adrenal tumours
	* carcinoid tumour

Introduction

	* pheochromocytomas arise from chromaffin cells and which secrete catecholamines
	* they are rare tumours, arising in only 2-8 people per million population
	* 85% arise from the adrenal (11% are malignant), 15% arise from extra-adrenal sources such as sympathetic ganglia (30% are malignant)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 07 Jun 2022 03:20:45 +0000</pubDate>
        </item>
        <item>
            <title>24 hour SuperCare pharmacies</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pharmacies24hr</link>
            <description>24 hour SuperCare pharmacies

introduction

	* the Victorian government has budgeted $24m and introduced a number of 24hr “Supercare” pharmacies to help take the load off EDs
	* 20 will be open by 2018, 5 opened in July 2016

north and western suburbs of Melbourne</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Jul 2016 00:34:32 +0000</pubDate>
        </item>
        <item>
            <title>pharmacology main index</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pharmacology</link>
            <description>pharmacology main index

some useful links

	* Australian Therapeutic Guidelines (ETG)
	* Drugs in pregnancy and lactation/breastfeeding (via ETG)
	* Drugs in pregnancy (via TGA)
	* MIMS online drug database
	* Access to Vic. DHS emergency drugs including antivenoms
	* VicTAG register of life saving drugs in Victorian hospitals (pdf)
	* PBS schedule - approved medications search
	* 24 hour SuperCare pharmacies
	* Victorian SafeScripts patient prescription database

	* Australian Law relating to …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Feb 2026 01:57:59 +0000</pubDate>
        </item>
        <item>
            <title>phenol toxicity</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=phenol</link>
            <description>phenol toxicity

see also:

	* toxicology
	* StatPearls

Introduction

	* phenol is toxic to humans
	* individuals may be exposed to phenol through breathing contaminated air or through skin contact in the workplace
	* Other exposures to phenol may occur through the use of phenol-containing medicinal products (including mouthwashes, toothache drops, throat lozenges, analgesic rubs, and antiseptic lotions) or smoking tobacco.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 04 Jun 2022 05:05:23 +0000</pubDate>
        </item>
        <item>
            <title>phenothiazines</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=phenothiazines</link>
            <description>phenothiazines

see also anti-psychotic medications

Introduction

	* closely related to tricyclic antidepressants chemically.
	* 2 main sub-groups:
		* aliphatic (eg. chlorpromazine (Largactil))
			* low clinical potency
			* medium extrapyramidal toxicity
			* high sedative actions
			* high hypotensive actions

		* piperazine (eg. fluphenazine)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 01 May 2009 00:13:28 +0000</pubDate>
        </item>
        <item>
            <title>phenylephrine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=phenylephrine</link>
            <description>phenylephrine

	* excessive topical use may cause hypertensive crisis which may be fatal, and attempts to treat such alpha agonist crises with beta adrenergic blockers or calcium channel blockers may cause acute pulmonary oedema (APO) and thus these agents are contra-indicated!!

introduction

	* an alpha adrenergic agonists type of sympathomimetic agent
	* often used in</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 21 Dec 2024 13:16:50 +0000</pubDate>
        </item>
        <item>
            <title>phenytoin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=phenytoin</link>
            <description>phenytoin

see also:

	* seizures

introduction

	* phenytoin is a sodium channel blocking anticonvulsant agent with antiarrhythmic properties (and thus potentially pro-arrhythmogenic)
	* many drug interactions (see below)

presentation

	* ampoules for iv use:
		* 100mg in 2ml 
		* 250mg in 5ml</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 21 Mar 2009 08:22:11 +0000</pubDate>
        </item>
        <item>
            <title>pholcodine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pholcodine</link>
            <description>pholcodine

see also:

	* opiates and opioids
	* antitussive cough medications

Introduction

	* morphine analogue opiate based antitussive cough medication which in many regions largely replaced codeine linctus as it has a much lower potential for dependence
	* helps suppress non-productive coughs
	* has a mild sedative effect, but has little or no analgesic effects</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 11 Apr 2023 06:32:15 +0000</pubDate>
        </item>
        <item>
            <title>phosphate</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=phosphate</link>
            <description>phosphate

see also:

	* calcium
	* parathyroid hormone (PTH)
	* vitamin D
	* calcitonin
	* hyperphosphataemia
	* hypophosphataemia

high phosphate diets probably not good for you

	* there is concern that high intake of phosphate containing beverages such as Diet Coke may lead to increased calcium excretion and thus increase risk of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 12 Mar 2025 01:04:02 +0000</pubDate>
        </item>
        <item>
            <title>phosphodiesterase inhibitors (PDE inhibitors)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=phosphodiesterase_inhibitors</link>
            <description>phosphodiesterase inhibitors (PDE inhibitors)

see also:

	* methylxanthines

introduction

	* phosphodiesterase is an enzyme that metabolises either cAMP (PDE 4,7,8), cGMP (PDE 5,6,9) or both (PDE 1,2,3,10,11) depending on the isoform.
	* in mammals, the PDE superfamily of enzymes is classified into 11 families, namely PDE1-PDE11.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 11 Nov 2009 08:19:55 +0000</pubDate>
        </item>
        <item>
            <title>phthalates</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=phthalates</link>
            <description>phthalates

see also:

	* endocrine disrupting chemicals (EDCs)
	* foods that may be toxic or bad for you
	* bisphenols (Bisphenol A (BPA), etc)
	* Perfluoroalkyl and polyfluoroalkyl substances (PFAS) including PFOA, PFOS, GenX, Teflon

Introduction

	* phthalates are a group of commonly used chemicals which have been found to potentially have adverse effects on humans and presumably other animals
	* these substances can break down into microscopic particles and enter the body through food, air,…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Apr 2026 01:09:53 +0000</pubDate>
        </item>
        <item>
            <title>physiology main index</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=physiology</link>
            <description>physiology main index

	* cellular physiology
		*  cellular physiology - endoplasmic reticulum

	* sodium physiology
	* potassium physiology
	* calcium
	* bone physiology
	* renal physiology
	* acid-base physiology
	* autacoids
		* Serotonin physiology
		* histamine physiology, receptors and antihistamines
		* Bradykinin and kinin physiology and pharmacology

	* eicosanoids &amp; prostaglandins
		* platelet activating factor

	* cytokines
	* fever - the febrile response to infections
	* immunology
	…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 May 2023 06:13:03 +0000</pubDate>
        </item>
        <item>
            <title>pelvic inflammatory disease (PID)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pid</link>
            <description>pelvic inflammatory disease (PID)

see also:

	* gynaecology
	* sexually transmitted infections (STDs/STIs)

introduction

	* PID is the general description given to inflammation caused by infection in the upper genital tract in females and includes salpingitis, endometritis, oophoritis, myometritis (uterine wall), and parametritis (broad ligament and uterine serosa).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 05:00:50 +0000</pubDate>
        </item>
        <item>
            <title>pityriasis rubra pilaris (PRP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pityriasis_rubra_pilaris</link>
            <description>pityriasis rubra pilaris (PRP)

see also:

	* dermatology

Introduction

	* a rare scaly chronic red/orange rash with thickening and scaling of the palms and soles forming palmoplantar keratoderma
	* classic forms usually go away in 3 to 5 years with or without treatment</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2026 05:41:11 +0000</pubDate>
        </item>
        <item>
            <title>Pharmacokinetics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pk</link>
            <description>Pharmacokinetics

see also:

	* pharmacology main index
	* absorption of drugs
	* distribution of drugs - volume of distribution, etc
	* metabolism of drugs
	* excretion of drugs
	* prescribing drugs in patients with liver impairment
	* Wikipedia rate equations for chemical reactions

Enzyme Kinetics:

zero order kinetics

	* rate of reaction is independent of the concentration of the reactant(s)
	* dX/dt = K
	* eg. saturated enzyme/transport system;infusion;
	* half life = [X]</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 09 Apr 2009 02:31:53 +0000</pubDate>
        </item>
        <item>
            <title>Absorption of drugs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pk_absorption</link>
            <description>Absorption of drugs

see also:

	* pharmacokinetics

Passage Of Drugs Through Membrane Barriers:

1. Aqueous diffusion:

	* Water soluble substances pass through aqueous “pores” in cell membranes or b/n cells at a rate according to Ficks' Law:
		* m/t = Pk A (Co-Ci) , where,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 09 Nov 2008 06:00:19 +0000</pubDate>
        </item>
        <item>
            <title>Distribution of drugs within the body</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pk_distribution</link>
            <description>Distribution of drugs within the body

see also:

	* pharmacokinetics

Introduction

	* The distribution of a drug throughout the body is governed by the affinity it has for various constituents of the tissues:
		* involvement in enteric circulations (eg. enterohepatic shunt) which increase persistence in the body, preventing distribution elsewhere;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 09 Nov 2008 06:38:35 +0000</pubDate>
        </item>
        <item>
            <title>Excretion of drugs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pk_excretion</link>
            <description>Excretion of drugs

see also:

	* pharmacokinetics

Introduction

	* The main routes of drug excretion are:
		* 1. urine;
		* 2. faeces;
		* 3. expired air (volatiles);


Urinary:

3 mechanisms involved in urinary excretion:

	* 1. Glomerular filtration:
		* rate drug enters filtrate depends on MW &amp; plasma conc.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 09 Nov 2008 07:06:40 +0000</pubDate>
        </item>
        <item>
            <title>prescribing drugs in patients with liver impairment</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pk_liverdisease</link>
            <description>prescribing drugs in patients with liver impairment

see also:

	* Pharmacokinetics
	* Metabolism of drugs
	* assessment of hepatic function
	* liver diseases
	* cirrhosis
	* hepatic encephalopathy

liver disease and drug Rx

	* decreased hepatic blood flow (eg. portosystemic shunts) will decrease metabolism rates of high extraction ratio drugs (see below)
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 Nov 2023 13:08:23 +0000</pubDate>
        </item>
        <item>
            <title>Metabolism of drugs</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pk_metabolism</link>
            <description>Metabolism of drugs

see also:

	* pharmacokinetics
	* prescribing drugs in patients with liver impairment

Introduction

	* Generally, the metabolism of a drug decreases its lipid solubility by making it more polar and thus more hydrophilic, thereby facilitating excretion;

Phase I reaction:

	* Occur when there is a change in the drug molecule such as oxidation, reduction, or hydrolysis;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 09 Apr 2009 02:32:57 +0000</pubDate>
        </item>
        <item>
            <title>placental insufficiency</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=placental_insufficiency</link>
            <description>placental insufficiency

see also:

	* Obstetrics
	* fetal growth restriction (FGR / SGA / IUGR)

Introduction

	* placental insufficiency is the failure of the placenta to deliver sufficient nutrients to the fetus during pregnancy
	* this does not include complete placental abruption which is a separate condition</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Aug 2019 08:01:19 +0000</pubDate>
        </item>
        <item>
            <title>plantar fasciitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=plantar_fasciitis</link>
            <description>plantar fasciitis

see also:

	* the painful foot
	* patient information:
		*  &lt;https://physioworks.com.au/injuries-conditions-1/plantar-fasciitis&gt;
		*  &lt;https://www.racgp.org.au/clinical-resources/clinical-guidelines/handbook-of-non-drug-interventions-(handi)/other/stretching-exercises-for-plantar-fasciitis&gt;


Introduction

	* one of the most common causes of foot pain and it is often bilateral
	* it is usually caused either by:
		*  repeatedly overstretched
		*  blunt trauma such as landing on…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 22 Jan 2026 06:39:24 +0000</pubDate>
        </item>
        <item>
            <title>stinging or dangerous contact plants in Australia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=plants_stinging</link>
            <description>stinging or dangerous contact plants in Australia

see also:

	* toxinology
	* &lt;https://www.greenlifeindustry.com.au/Attachment?Action=Download&amp;Attachment_id=1560&gt;

Introduction

	* many plants as well as many mushrooms are toxic if eaten, however this page relates to those which are either painful or otherwise cause issues when touched
	* some other plants are toxic if burnt and the smoke inhaled such as oleander</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 24 Sep 2020 09:06:57 +0000</pubDate>
        </item>
        <item>
            <title>plasmids</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=plasmids</link>
            <description>plasmids

see also:

	* microbiology
	* antiviral agents
	* prions
	* viroids - obelisks
	* viruses

Introduction

	* plasmids are small circular double stranded DNA molecules which reside in bacteria and some eukaryote cells but are separate from the cell's chromosomal DNA and can replicate independently
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Dec 2024 22:39:18 +0000</pubDate>
        </item>
        <item>
            <title>plaster application</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=plaster_application</link>
            <description>plaster application

see also:

	* plaster tutes and templates for slabs (courtesy of Dr Douros from Austin Health and EDTeaching.com and LITFL):
		* Charnley slab for Colles (pdf)
		* Thumb spica for scaphoid (pdf)
		* Volar slab  (pdf)
		* Cam walker (pdf)
		* Plaster templates (pdf)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 23 Apr 2014 07:06:21 +0000</pubDate>
        </item>
        <item>
            <title>plastic surgery</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=plastics</link>
            <description>plastic surgery

	* animal bites
	* cellulitis
	* Periorbital and orbital cellulitis
	* necrotizing fasciitis
	* skin necrosis
	* removal of embedded fish hooks
	* burns
	* local anaesthetic agents
	* paediatric lacerations
	* facial trauma
	* the injured hand
	* fractures of the metacarpal
	* fractures and dislocations of the fingers

other resources

	* EMRAPTV Episode 77: How to Sew a Flap
	* Eaton Hand Plastic Surgery Resource</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:42:57 +0000</pubDate>
        </item>
        <item>
            <title>pleural effusion</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pleural_effusion</link>
            <description>pleural effusion

see also:

	* the chest X-ray (CXR)
	* acute pulmonary oedema (APO)
	* LITFL pleural fluid analysis

introduction

	* pleural effusion is the collection of fluid other than blood, lymph or pus between the two layers of pleura outside the lung (NB. a collection of blood is a haemothorax, a collection of lymph is a chylothorax while collection of pus is an empyema)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Dec 2022 00:48:51 +0000</pubDate>
        </item>
        <item>
            <title>progressive multifocal leukoencephalopathy (PML)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pml</link>
            <description>progressive multifocal leukoencephalopathy (PML)

see also:

	* viruses
	* neurology
	* AIDS
	* encephalopathy

introduction

	* a rare, but often fatal demyelinating disease of the central nervous system caused by reactivation of human polyomavirus (the JC virus - named after the patient it was initially cultivated from - John Cunningham)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 17 Mar 2013 06:15:14 +0000</pubDate>
        </item>
        <item>
            <title>polymyalgia rheumatica</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pmr</link>
            <description>polymyalgia rheumatica

see also:

	* rheumatology
	* Vic. DHS Better Health Channel - patient fact sheet on PMR

introduction

	* PMR is a clinical syndrome characterized by severe aching and stiffness in the neck, shoulder girdle, and pelvic girdle. 
	* closely linked to temporal arteritis (giant cell arteritis)
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Aug 2024 03:02:41 +0000</pubDate>
        </item>
        <item>
            <title>pneumococcus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pneumococcus</link>
            <description>pneumococcus

see also:

	* clinically important bacteria
	* pneumonia
	* community acquired pneumonia (CAP) in adults
	* meningitis
	* wikipedia

introduction

	* the pneumococcus (Streptococcus pneumoniae) is a Gram-positive, alpha-hemolytic, aerotolerant anaerobic Strept. discovered in 1881, and called Diplococcus pneumoniae in 1920 but renamed in 1974 to its current name.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Jan 2014 05:49:05 +0000</pubDate>
        </item>
        <item>
            <title>pneumoconiosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pneumoconiosis</link>
            <description>pneumoconiosis

see also:

	* interstitial lung disease
	* respiratory medicine

Introduction

	* fibrotic lung diseases caused by inhalation of dusts in occupational exposures
	* these are generally not treatable and may result in progressive pulmonary fibrosis and eventually respiratory failure, and in some cases may result in lung cancers (eg. mesothelioma with asbestosis)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 03 Dec 2016 12:25:56 +0000</pubDate>
        </item>
        <item>
            <title>pneumomediastinum</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pneumomediastinum</link>
            <description>pneumomediastinum

see also:

	* pathophysiology of mechanical ventilation
	* asthma
	* oesophageal rupture - Boerhaave syndrome
	* J Thorac Dis. 2015 Feb; 7(Suppl 1): S44–S49. Pneumomediastinum 

Introduction

	* pneumomediastinum is air within the mediastinum which is usually readily visible on a plain CXR and it may arise from either:
		* air leaks through small alveolar ruptures to the surrounding bronchovascular sheath as with spontaneous pneumomediastinum (SPM) which is generally benign an…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Aug 2018 07:21:10 +0000</pubDate>
        </item>
        <item>
            <title>pneumonia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pneumonia</link>
            <description>pneumonia

	* RCH guideline - pneumonia
	* Adult community acquired pneumonia mortality risk scoring tool
	* AFTB lectures - community acquired pneumonia (CAP)
	* community acquired pneumonia (CAP) in adults
	* hospital acquired pneumonia (HAP)
	* pneumococcus
	* tuberculosis (TB)
	* Legionella (Legionaire's disease)
	* psittacosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 15 Dec 2021 01:50:06 +0000</pubDate>
        </item>
        <item>
            <title>hospital acquired pneumonia (HAP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pneumonia_hosp</link>
            <description>hospital acquired pneumonia (HAP)

see also:

	* RCH guideline - pneumonia
	* community acquired pneumonia (CAP) in adults</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 15 Dec 2021 01:50:48 +0000</pubDate>
        </item>
        <item>
            <title>hypersensitivity pneumonitis / bird fancier's lung / farmer's lung</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pneumonitis_hs</link>
            <description>hypersensitivity pneumonitis / bird fancier's lung / farmer's lung

see also:

	* respiratory medicine
	* acute dyspnoea / shortness of breath (SOB)
	* psittacosis

Introduction

	* hypersensitivity pneumonitis (HP, formerly called EAA extrinsic allergic alveolitis) is a form of interstitial lung disease with T cell lymphocytic infiltration and granulomatous inflammation in the bronchioles and alveoli</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 Dec 2022 02:42:50 +0000</pubDate>
        </item>
        <item>
            <title>pneumothorax</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pneumothorax</link>
            <description>pneumothorax

	* tube thoracostomy for Rx of pneumothorax and haemothorax
	* thoracic surgery
	* RCH guideline - pneumothorax
	* RCH guideline - needle thoracentesis
	* The University of Queensland Portal for Chest Tube Insertion
	* AFTB lecture - spontaneous pneumothorax
	* British Thoracic Society guidelines spontaneous pneumothorax (pdf)
	* Fact Sheet for patients

introduction

	* spontaneous pneumothorax: 
		* can be divided into:
			* primary:
				* no clinically evident underlying lung pa…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 13 May 2023 02:25:26 +0000</pubDate>
        </item>
        <item>
            <title>paroxysmal nocturnal haemoglobinuria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pnhb</link>
            <description>paroxysmal nocturnal haemoglobinuria

see also:

	* renal medicine (nephrology)
	* wikipedia

introduction

	* sometimes referred to as Marchiafava-Micheli syndrome, is a rare, acquired, potentially life-threatening disease of the blood characterised by complement-induced hemolytic anaemia, red urine (due to the appearance of haemoglobin in the urine) and thrombosis (in 40% of patients during their life).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 18 Jan 2010 04:23:26 +0000</pubDate>
        </item>
        <item>
            <title>police and the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=police_ed</link>
            <description>police and the ED

see also:

	* when are doctors required to compulsorily report patients in Australia
	* searching patients, suspicious behaviour, unknown substance, weapons or crime within the ED

Contacting Police to assist with Management of Patient or Visitor Behaviour

	* In Australia, police are to be contacted on “000” (not the local police station) and will require:
		*  Name, telephone number and location of incident;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 09 Jan 2023 04:13:37 +0000</pubDate>
        </item>
        <item>
            <title>polio</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=polio</link>
            <description>polio

see also:

	* viruses

introduction

	* a once common viral infection which can infect the spinal cord (transverse myelitis) and cause permanent paralysis
	* now re-emerging in Africa, Pakistan and the Middle East

clinical features

	* often asymptomatic</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 02 Jun 2014 02:05:23 +0000</pubDate>
        </item>
        <item>
            <title>polonium poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=polonium</link>
            <description>polonium poisoning

see also:

	* radiation injury
	* Ionising radiation
	* bio-weapons / biological weapons

Introduction

	* polonium-210 was used in the assassination of Alexandre Litvinenko in London in 2006

polonium-210

	* decays by alpha particle emission to lead-206 and thus is NOT detected by usual ionising radiation detectors and whilst outside the body, it does not pose harm as alpha particles can only travel a few centimetres in air</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 Sep 2020 08:46:41 +0000</pubDate>
        </item>
        <item>
            <title>polycystic kidney disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=polycystic_kidney</link>
            <description>polycystic kidney disease

see also:

	* renal medicine (nephrology)
	* Vic Better health Channel - polycystic kidney disease

introduction

ADPKD

	* autosomal dominant polycystic kidney disease (ADPKD) is one of the most common inherited disorders in humans affecting ~ 0.1% of the population, but does not usually present until middle age</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 14 Jan 2026 07:45:49 +0000</pubDate>
        </item>
        <item>
            <title>polycythaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=polycythaemia</link>
            <description>polycythaemia

introduction

	* excessive concentration of RBCs in the peripheral blood
	* increased RBC mass enlarges the vascular bed, decreases peripheral resistance and increases cardiac output and improves oxygen transport
	* HOWEVER, an excessively high RBC mass causes high viscosity and this may increase the risk of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 14 Dec 2022 08:30:21 +0000</pubDate>
        </item>
        <item>
            <title>polymyositis (PM)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=polymyositis</link>
            <description>polymyositis (PM)

see also:

	* dermatomyositis
	* inclusion body myositis (IBM)
	* connective tissue (CT) disorders

introduction

	* a chronic inflammatory myopathy related to dermatomyositis and inclusion body myositis (IBM)
	* like dermatomyositis, there is a link to underlying cancers but the link is less so, and mainly linked to non-Hodgkin lymphoma, lung cancer and bladder cancer cancers
	* ~100-200 cases per million</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 27 Sep 2013 06:33:46 +0000</pubDate>
        </item>
        <item>
            <title>population-attributable fraction (PAF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=population_attributable_fraction</link>
            <description>population-attributable fraction (PAF)

see also:

	* epidemiology
	* risk factor and treatment benefit metrics
	* WHO: PAF calculation
	* wikipedia: attributable fraction for the population
	* wikipedia: attibutable fraction among the exposed

Introduction

	* PAF is the proportional reduction in population disease or mortality that would occur if exposure to a risk factor were reduced to an alternative ideal exposure scenario.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Apr 2020 03:00:59 +0000</pubDate>
        </item>
        <item>
            <title>pork-cat syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pork_cat</link>
            <description>pork-cat syndrome

see also:

	* allergy and hypersensitivity reactions
	* anaphylaxis
	* tick-induced mammalian red meat allergy (MMA) / alpha-gal syndrome

Introduction

	* some people with cats develop an allergy to eating pork as the allergic response to the albumin produced from the cat's liver cross-reacts with albumin in pork creating a acute allergic reaction soon after eating it</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Mar 2019 13:43:57 +0000</pubDate>
        </item>
        <item>
            <title>porphyrias</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=porphyrias</link>
            <description>porphyrias

see also:

	* acute intermittent porphyria (AIP)

introduction

	* porphyrias (Gk: purple) are a group of mainly hereditary conditions affecting heme metabolism resulting in accumulation and increased excretion of porphyrins and their precursors
	* all are autosomal dominant except for congenital erythropoietic porphyria (CEP), which is autosomal recessive</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Apr 2014 06:56:05 +0000</pubDate>
        </item>
        <item>
            <title>portal hypertension</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=portal_hypertension</link>
            <description>portal hypertension

see also:

	* cirrhosis

Introduction

	* portal venous hypertension is primarily a result of cirrhosis

Aetiology

	* cirrhosis - by far the most common cause
	* pre-hepatic causes:
		* portal vein thrombosis - presents as N/V/D, abdo pain (intestinal ischaemia) +/- varices, splenomegaly</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Aug 2018 08:23:39 +0000</pubDate>
        </item>
        <item>
            <title>Mx of the newly intubated patient in ED - post-intubation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=post-intubation</link>
            <description>Mx of the newly intubated patient in ED - post-intubation

see also:

	* rapid sequence induction (RSI) for emergency intubation
	* assisted ventilation
	* extubation

immediate tasks

	* initial confirmation of successful intubation of the trachea
		* end-tidal CO2 (EtCO2) determination (either colorimetric or quantitative) is the most accurate means of confirming ETT placement in most circumstances and should be used for every intubation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 27 Mar 2016 22:14:08 +0000</pubDate>
        </item>
        <item>
            <title>post-coital emergency contraception</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=postcoital_contraception</link>
            <description>post-coital emergency contraception

see also gynaecology; contraception

	* RANZCOG guideline emergency contraception (pdf)

counselling:

	* do pregnancy test if pregnancy possible although:
		* no evidence that it will adversely effect the fetus if given in early pregnancy or if it fails to prevent pregnancy
		* may not prevent pregnancy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 21 Jan 2025 06:16:53 +0000</pubDate>
        </item>
        <item>
            <title>potassium physiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=potassium</link>
            <description>potassium physiology

see also:

	* hypokalaemia
		* Western Health procedure: Potassium chloride infusion

	* hyperkalaemia
	* sodium physiology

potassium physiology and homeostasis

total body potassium

	* total body potassium
		* = 45 meq/kg (young adult males as mainly prop.to muscle mass);
		* = 20 meq/kg (malnourished, wasted person);</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Dec 2014 03:16:35 +0000</pubDate>
        </item>
        <item>
            <title>postural orthostatic tachycardia syndrome (POTS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pots</link>
            <description>postural orthostatic tachycardia syndrome (POTS)

see also:

	* dysautonomia syndromes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:22:31 +0000</pubDate>
        </item>
        <item>
            <title>poverty</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=poverty</link>
            <description>poverty

see also:

	* social issues
	* homelessness / no fixed abode
	* domestic violence
	* addiction medicine (alcohol and other substance use)

Introduction

	* rent is a major expense
		*  in 2025, for those on pensions, 70-75% of single retirees who rent are living below the poverty line, while almost half of retired couples live below the poverty line if they rent</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 10 Feb 2025 01:36:29 +0000</pubDate>
        </item>
        <item>
            <title>post-partum haemorrhage (PPH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pph</link>
            <description>post-partum haemorrhage (PPH)

see also:

	* ED Mx of 3rd stage of labour
	* massive blood transfusions
	* the shocked hypotensive patient
	* post-partum / puerperial complications

introduction

	* Primary PPH: Genital tract blood loss ≥ 500mL during the third stage of labour and up to 24 hours after birth
		* major PPH is defined as loss &gt; 1000mL blood

	* Secondary PPH:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 02:17:58 +0000</pubDate>
        </item>
        <item>
            <title>proton pump inhibitors (PPIs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ppis</link>
            <description>proton pump inhibitors (PPIs)

see also peptic ulcer disease; gastro-oesophageal reflux; pharmacology main index

introduction

	* acid pump (gastric H+,K+ ATPase) inhibitors
		* result in decreased basal &amp; stimulated gastric acid secretion irrespective of stimuli;


examples

omeprazole (Losec):

	* 1st PPI
	* PU dose:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Nov 2017 10:01:19 +0000</pubDate>
        </item>
        <item>
            <title>pre-operative assessment</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pre-op</link>
            <description>pre-operative assessment

see also:

	* general surgery

introduction

	* for emergency surgery, pre-op assessment uncommonly alters course or outcome of surgery as the urgency takes precedence
	* pre-op cardiac risk assessment is required for elective surgery dependent upon</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Mar 2019 08:50:19 +0000</pubDate>
        </item>
        <item>
            <title>pre-eclampsia and eclampsia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=preeclampsia</link>
            <description>pre-eclampsia and eclampsia

see also Obstetrics

hypertension in pregnancy

risk factors for pregnancy-induced HT:

	* nulliparity (3x) (but HELLP syndrome has a pre-dilection for multigravids)
	* age &gt; 40yrs (3x)
	* African American race (1.5x)
	* FH pregnancy-induced HT (5x)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 02 Oct 2012 07:59:33 +0000</pubDate>
        </item>
        <item>
            <title>pregabalin (Lyrica)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pregabalin</link>
            <description>pregabalin (Lyrica)

see also:

	* gabapentinoids
	* gabapentin (Neurontin)
	* neuropathic pain

Introduction

	* pregabalin is marketed as Lyrica and is structurally similar to gabapentin (Neurontin), another gabapentinoid anticonvulsant medication which is also used for chronic pain
	* see gabapentin (Neurontin) for actions, etc

Dosage

	* usual adult starting dose 75mg bd</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 11 Jul 2025 06:38:04 +0000</pubDate>
        </item>
        <item>
            <title>pregnancy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pregnancy</link>
            <description>pregnancy

see also:

	* hyperemesis gravidarum
		* Rh isoimmunisation and Anti-D prophylaxis
		* PV bleeding in early pregnancy - miscarriage, ectopic pregnancy and more
			* miscarriage
			* ectopic pregnancy
			* molar pregnancy - hydatidiform mole, choriocarcinoma
			* foetal / fetal medicine

		* PV bleeding in late pregnancy - abruption, placenta praevia and more
		* trauma in the pregnant patient
		* mid-trimester issues and complications
		* pre-eclampsia and eclampsia
		* labour
		* pre…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Oct 2025 00:45:59 +0000</pubDate>
        </item>
        <item>
            <title>prescribing in pregnancy - is the medicine safe?</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pregnancy_meds</link>
            <description>prescribing in pregnancy - is the medicine safe?

see also:

	* pregnancy
		* &lt;https://www.tga.gov.au/products/medicines/find-information-about-medicine/prescribing-medicines-pregnancy-database&gt;
		* Australian Prescriber 2011 - analgesics in pregnancy and breastfeeding

medication safety class in pregnancy
TGA category    meaning  Cat A  Appears to be safe Medications that have been taken by a large number of pregnant women or women of child bearing age without evidence of an increase in foetal …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 11 Apr 2024 11:51:37 +0000</pubDate>
        </item>
        <item>
            <title>fetal radiation doses in pregnancy Xrays and CT scans</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pregnancy_rad</link>
            <description>fetal radiation doses in pregnancy Xrays and CT scans

see also:

	* pregnancy
	* radiology
	* Ionising radiation
	* radiation injury
	* Emerg Med Australasia (2018): 30, 749-753 Morton and Teasdale

Introduction

	* the risk-benefits of radiologic investigations in pregnancy and lactation need to be considered</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 14 Apr 2024 06:27:16 +0000</pubDate>
        </item>
        <item>
            <title>shortness of breath (SOB/dyspnoea) in pregnancy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pregnancy_sob</link>
            <description>shortness of breath (SOB/dyspnoea) in pregnancy

see also:

	* pregnancy

Introduction

	* SOB is a common symptom in pregnancy and is commonly physiologic in the 2nd half of pregnancy, but there are important conditions which need to be considered

Aetiology</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 31 Dec 2018 06:55:15 +0000</pubDate>
        </item>
        <item>
            <title>unintended or unplanned pregnancies and termination / STOP</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pregnancy_unintended</link>
            <description>unintended or unplanned pregnancies and termination / STOP

see also:

	* contraception
	* mifepristone / RU486
	* &lt;https://www.msiaustralia.org.au/abortion-services/medical-abortion/&gt;

introduction

	* unintended pregnancies have a high psychosocial and often financial cost
	* most women and their partners, do not consider termination of these pregnancies without enormous psychologic stress at the time or the pregnancy, and later in life in often still raises psychologic issues.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 28 Dec 2025 05:18:05 +0000</pubDate>
        </item>
        <item>
            <title>premenstrual syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=premenstrual_synd</link>
            <description>premenstrual syndrome

see also:

	* gynaecology
	* dysmenorrhoea

introduction

	* refers to a symptom complex occurring monthly during the luteal phase (ovulation to menstruation but may last 3 to 21 days per cycle) of the menstrual cycle which includes:
		* nausea, vomiting, headache, nervousness, fatigue, diarrhoea, syncope, lower abdominal cramping, bloating, breast tenderness, mood changes, backache, and dizziness.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 27 Jan 2009 06:06:43 +0000</pubDate>
        </item>
        <item>
            <title>posterior reversible encephalopathy syndrome (PRES)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pres</link>
            <description>posterior reversible encephalopathy syndrome (PRES)

see also:

	* encephalopathy
	* hypertension

Introduction

	* a form of acute hypertensive encephalopathy usually associated with acute severe hypertension which usually resolves within 1-2 weeks of resolution of the hypertension but some may be left with neurologic impairment and in a minority it may result in death</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Aug 2018 13:25:01 +0000</pubDate>
        </item>
        <item>
            <title>presbycusis (deafness of aging)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=presbycusis</link>
            <description>presbycusis (deafness of aging)

see also:

	* deafness / hearing loss
	* sensorineural hearing loss / deafness
	* drug induced ototoxicity
	* endolymphatic hydrops including Meniere's disease
		* in contrast, is mainly low frequency hearing loss


introduction

	* gradual age-related loss of hearing initially is a high tone hearing loss and is associated with difficulty in speech discrimination, particularly in noisy environments, and becomes a major impediment and socially isolating factor for…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Feb 2026 00:24:36 +0000</pubDate>
        </item>
        <item>
            <title>prescribing medications in Australia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prescribing</link>
            <description>prescribing medications in Australia

see also:

	* pharmacology main index
	* electronic prescribing
	* Australian Pharmaceutical Benefits Scheme (PBS) 

introduction

	* prescribing medications in Australia is controlled by Federal laws including:
		* Drugs, Poisons and Controlled Substances Act 1981

	* medical boards investigating doctors' inappropriate or dangerous prescribing including failure to comply with regulations, have usually been a result of either:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 25 Oct 2016 04:27:45 +0000</pubDate>
        </item>
        <item>
            <title>electronic prescribing</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prescribing_electronic</link>
            <description>electronic prescribing

see also:

	* prescribing medications in Australia

legal criteria for computer generated prescriptions in Australia

	* the computer program will restrict access to the prescription printing module to authorised persons
	* prescriptions will be generated only by authorised persons</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 29 Mar 2009 08:36:31 +0000</pubDate>
        </item>
        <item>
            <title>preterm labour / premature labour</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=preterm_labour</link>
            <description>preterm labour / premature labour

see also:

	* labour

introduction

risk factors

	* UTI / pyelonephritis
	* Abruption
	* Cervical incompetence
	* Cervical surgical procedures
	* Uterine anomalies
	* Polyhydramnios
	* Smoking
	* Illicit drug use
	* Multiple gestation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 03 Apr 2023 22:52:54 +0000</pubDate>
        </item>
        <item>
            <title>priapism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=priapism</link>
            <description>priapism

see also:

	* urology

Introduction

	* priapism is the unwanted, very prolonged (more than 4hrs without sexual stimulation) erection of the penis which may constitute a rare urologic emergency as risk of permanent scarring of the penis increases after 4hrs of ischaemic priapism and occurs in all patients after 48hrs of ischaemic priapism, this may result in disfigurement, erectile dysfunction or in severe cases, penile gangrene</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Dec 2024 04:02:38 +0000</pubDate>
        </item>
        <item>
            <title>prions</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prions</link>
            <description>prions

see also:

	* microbiology
	* wikipedia

introduction

	* prions are protein rods that are the cause of a class of diseases called subacute spongiform encephalopathies.
	* prions induce existing endogenous prion protein (PrPC) in the host organism to take on extremely stable, rogue mis-folded forms (PrP</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 Dec 2010 11:03:25 +0000</pubDate>
        </item>
        <item>
            <title>patient privacy and confidentiality</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=privacy</link>
            <description>patient privacy and confidentiality

see also:

	* medico-legal issues in the ED
	* &lt;https://ovic.vic.gov.au/privacy/for-the-public/your-privacy-rights/&gt;
	* &lt;https://www.oaic.gov.au/privacy/guidance-and-advice/guide-to-health-privacy/chapter-3-using-or-disclosing-health-information/&gt;

Introduction

	* patient privacy and confidentiality are core principles of medical care and unless there are specific or extenuating circumstances private information should not be disclosed to third parties witho…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 09 Nov 2020 00:09:25 +0000</pubDate>
        </item>
        <item>
            <title>phosphatases of regenerating liver (PRLs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prls</link>
            <description>phosphatases of regenerating liver (PRLs)

see also:

	* neoplastic spread
	* oncology

Introduction

	* phosphatases of regenerating liver (PRLs) are a family of proteins involved in cell growth and metabolism
	* PRLs exist in all kinds of single- and multi-cell animals, and the role of PRLs in</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 May 2023 06:35:19 +0000</pubDate>
        </item>
        <item>
            <title>Probenecid</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=probenecid</link>
            <description>Probenecid

see uricosuric agents, gout

Summary

	* Developed in 1951 to decr. penicillin excretion but also decr. excretion of a no. other drugs (eg. indocid, methotrexate, sulphonamides, cephalosporins, active metab. of clofibrate) but uric acid is the only important endogenous compound whose excretion is incr. by probenecid;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 30 Sep 2008 11:42:03 +0000</pubDate>
        </item>
        <item>
            <title>procainamide</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=procainamide</link>
            <description>procainamide

see also:

	* anti-arrhythmic agents

introduction

	* Vaughan-Williams class Ia sodium channel blocking agent sometimes used in attempted cardioversion of tachyarrhythmias such as:
		* SVT or AF associated with WPW


administration

	* 20 to 50 mg/minute given intravenously while monitoring the blood pressure closely every 5 to 10 minutes until either:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Oct 2013 02:35:51 +0000</pubDate>
        </item>
        <item>
            <title>procedural sedation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=procedural_sedation</link>
            <description>procedural sedation

see also:

	* clinical procedures in the ED
	* WH Paediatric procedural sedation - intranet only</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 04 Apr 2019 21:28:35 +0000</pubDate>
        </item>
        <item>
            <title>minimum coagulation parameters for safe invasive procedures in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=procedures_coags</link>
            <description>minimum coagulation parameters for safe invasive procedures in the ED

see also:

	* clinical procedures in the ED

lumbar puncture

	* need to weigh risk of causing a serious spinal haematoma or other bleeding complication vs benefits, if moderate risk but LP needed, consider flouroscopic LP to minimise bleeding risk</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 05 May 2018 04:19:08 +0000</pubDate>
        </item>
        <item>
            <title>prochlorperazine (Stemetil)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prochlorperazine</link>
            <description>prochlorperazine (Stemetil)

see also:

	* phenothiazines
	* migraine
	* anti-emetics

introduction

	* prochlorperazine is a phenothiazine antiemetic which is mainly used in the Rx of ED Mx of vertigo and BPV and severe migraine

adverse effects

	* adverse effects are similar to all phenothiazines and include:
		* extrapyramidal reactions such as oculogyric crisis, dystonic reactions, akathisia such as oculogyric crises, akathisia, dystonic reactions and if used long term, irreversible tardive…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 07:35:10 +0000</pubDate>
        </item>
        <item>
            <title>proctitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=proctitis</link>
            <description>proctitis

see also:

	* ano-rectal pain
	* tenesmus

Introduction

	* inflammation of the rectum

Aetiology

	* ulcerative colitis
	* Crohn's disease
	* idiopathic ulcerative proctitis
	* coeliac disease
	* radiation
	* ischaemic proctitis due to hypotensive episodes, anaphylaxis or systemic lupus erythematosus (SLE)
	* non-steroidal anti-inflammatory drugs (NSAIDs)
	* caustic agents such as cleaning solutions
	* diversion proctitis - prior surgery leading to diversion of faecal flow from rectu…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Jun 2018 12:24:38 +0000</pubDate>
        </item>
        <item>
            <title>medical professionalism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=professionalism</link>
            <description>medical professionalism

see also:

	* stress in ED doctors
	* administrative aspects of Emergency Medicine in Australia
	* conflict of interest for employees of hospitals and members of committees and boards of management

core ethical principles for doctors

respect

	* respecting a patient's own autonomy, the right of individuals to make decisions on their own behalf

beneficence

	* the duty to do the best for the individual patient</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Nov 2013 00:52:31 +0000</pubDate>
        </item>
        <item>
            <title>progestogens</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=progestogens</link>
            <description>progestogens

see also:

	*  gynaecology
	*  contraception
	*  antiprogestogens

introduction

	* by far the main progestin is progesterone, but small amounts of 17-alpha-OH progesterone are also secreted;
	* males secrete 1-5mg progesterone per day  &amp; level is only slightly higher in females during follicular phase</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 29 Dec 2024 19:35:25 +0000</pubDate>
        </item>
        <item>
            <title>prolactin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prolactin</link>
            <description>prolactin

see also:

	* hormones

Introduction

	* prolactin is a peptide hormone secreted from the pitiutary gland in response to eating, mating, oestrogen treatment, ovulation and nursing
	* confirmed in humans in 1970
	* crucial for milk production during pregnancy and lactation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 18 Jan 2025 02:24:55 +0000</pubDate>
        </item>
        <item>
            <title>prolonged QTc</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prolongedqtc</link>
            <description>prolonged QTc

see also:

	* The basics of reading an ECG
	* patterns of ECGs
	* torsade de pointes VT
	* short QTc
	* LITFL - a case of prolonged QTc with R on T bigeminy leading to torsades

	* avoid prescribing drugs known to cause prolonged QTc to patients at high risk of, or known to have prolonged QTc!
	* patients are particularly at risk if they also have bradycardia

introduction

	* the QT interval on the ECG is measured from the start of QRS complex to end of the T wave</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:49:34 +0000</pubDate>
        </item>
        <item>
            <title>propofol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=propofol</link>
            <description>propofol

see also:

	*  anaesthetics

	* must only be used by senior experienced doctors with resuscitation facilities.
	* shake ampoule before use.
	* not for pregnancy, neonates, lactation or children aged under 3 years
	* use with extra care in patients at risk of severe hypotension</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Jul 2024 00:42:13 +0000</pubDate>
        </item>
        <item>
            <title>propranolol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=propranolol</link>
            <description>propranolol

see also: beta adrenergic blockers

Stability &amp; preparation:

	* 10, 40, 160mg dark pink tabs; 1mg/ml 1ml ampoule;
	* Racemic mixture 1:1 ratio - only (-) enantiomer active;

Absorption:

	* Highly lipophilic, almost completely absorbed orally, but 1st pass -&gt; only 25% (dose dependant as ? saturable 1st pass) reaches syst.circul.;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Feb 2009 10:05:45 +0000</pubDate>
        </item>
        <item>
            <title>prosopagnosia (impaired facial recognition / blindness)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prosopagnosia</link>
            <description>prosopagnosia (impaired facial recognition / blindness)

see also:

	* neurology

Introduction

	* the ability to recognise faces is a critical component of social networking and for most people, they are excellent at recognising a wide range of faces
	* recognising someone sends them a signal that they are important to you</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Feb 2023 04:43:06 +0000</pubDate>
        </item>
        <item>
            <title>prostaglandins</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prostaglandins</link>
            <description>prostaglandins

see also:

	* eicosanoids including prostaglandins
	* corticosteroids
	* non-steroidal anti-inflammatory drugs (NSAIDs)

introduction

	* prostaglandins are substances derived from membrane phospholipids via the actions of the enzymes phosholipase A2, phospholipase C and then cyclooxygenase
	* these metabolic products of phospholipids and arachidonic acid are</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Oct 2013 06:24:07 +0000</pubDate>
        </item>
        <item>
            <title>prostatitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prostatitis</link>
            <description>prostatitis

see also:

	* urinary tract infections (UTIs) / cystitis
	* benign prostatic hyperplasia (BPH)
	* &lt;https://www.andrologyaustralia.org/wp-content/uploads/Factsheet_Prostatitis.pdf&gt;

introduction

	* prostatitis is an infection or inflammation of the prostate
	* there are said to be 4 syndromes:
		* acute bacterial prostatitis (5% of cases)
			*  usually men with chronic IDCs, immunocompromised (incl. diabetes), intermittent self-catheterisation or following prostatic biopsy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 03:34:22 +0000</pubDate>
        </item>
        <item>
            <title>protein losing enteropathy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=protein_losing_enteropathy</link>
            <description>protein losing enteropathy

see also:

	* diarrhoea

Introduction

	* protein-losing enteropathy is any condition which causes damage to the gut wall or obstructs lymphatic drainage with resultant loss of plasma proteins into the gut lumen

Clinical features</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Aug 2018 11:26:07 +0000</pubDate>
        </item>
        <item>
            <title>protein metabolism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=protein_metabolism</link>
            <description>protein metabolism

see also:

	* pathology tests - urea and creatinine

basic overview

	* proteins conjugated with ubiquitin are destined for degradation
	* dietary amino acids and the amino acids that form from catabolism of protein form an amino acid pool
	* the fate of these amino acids may take several routes:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jan 2009 04:54:19 +0000</pubDate>
        </item>
        <item>
            <title>proteome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=proteome</link>
            <description>proteome

see also:

	* foods that may be toxic or bad for you
	* risk and the perception of risk
	* air pollution and health risks
	* the GIT microbiome
	* genomics
	* metabolome
	* exposome and health
	* transcriptome

Introduction

	* the proteome generally refers to the individual patient's collection of proteins which can be found in the blood or in tissues and which may reflect pathogens, metabolic and hormonal activity, immunologic status, etc</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Aug 2025 00:32:35 +0000</pubDate>
        </item>
        <item>
            <title>Pro-Thrombotic Screen</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prothrombotic_screen</link>
            <description>Pro-Thrombotic Screen

Coagulation tests

	*  PT
	*  APTT
	*  Protein C, S
	*  antithrombin 3
	*  Fasting homocystine
	*  antiphospholipid antibodies
	*  lupus anticoagulant (anticardiolipin antibodies)
	*  G20210A prothrombin gene mutation
	*  Factor V leiden deficiency</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 30 Sep 2010 09:33:10 +0000</pubDate>
        </item>
        <item>
            <title>pruritus or itching</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pruritus</link>
            <description>pruritus or itching

see also:

	* paraesthesiae or numbness

Introduction

	* itch is a protective cutaneous somatosensory modality that drives reflexive scratching to remove harmful parasites and irritants from the skin.
	* the itching response with subsequent scratching is activated by two distinct neural pathways:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Aug 2019 09:43:13 +0000</pubDate>
        </item>
        <item>
            <title>polycythaemia rubra vera</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=prv</link>
            <description>polycythaemia rubra vera

see also:

	* polycythaemia
	* &lt;https://en.wikipedia.org/wiki/Polycythemia_vera&gt;

introduction

	* myeloproliferative disorder resulting in polycythaemia
	* ~10 new cases per million population per year
	* incidences of polycythaemia vera, essential thrombocytosis, and myelofibrosis were 10x higher among Ashkenazi Jews in northern Israel than in persons of Arabic descent in the region.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 08 Sep 2025 12:11:55 +0000</pubDate>
        </item>
        <item>
            <title>prostate specific antigen (PSA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psa</link>
            <description>prostate specific antigen (PSA)

see also:

	* prostate cancer
	* benign prostatic hyperplasia (BPH)
	* NNT.com - PSA screening does NOT decrease deaths from prostate cancer but increases risk of biopsies and prostatectomy with their potentially relatively high morbidities

prostate specific antigen

	* PSA is a serine protease produced by prostatic epithelium and secreted into semen
	* its normal function is to cleave and liquefy the seminal coagulum formed after ejaculation.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Dec 2013 07:51:29 +0000</pubDate>
        </item>
        <item>
            <title>primary sclerosing cholangitis / primary biliary cirrhosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pscholangitis</link>
            <description>primary sclerosing cholangitis / primary biliary cirrhosis

see also:

	* ascending cholangitis
	* inflammatory bowel disease (IBD)

Introduction

	* primary sclerosing cholangitis (PSC) is a rare condition which is mainly associated with patients with inflammatory bowel disease (IBD) and usually is diagnosed when persistently high AP levels are found as it is usually asymptomatic in the early phases</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 27 Mar 2026 22:16:58 +0000</pubDate>
        </item>
        <item>
            <title>pseudomembranous colitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pseudomembranous_colitis</link>
            <description>pseudomembranous colitis

see also:

	* Clostridium difficile
	* colitis

Introduction

	* a form of generally diffuse colitis resulting from antibiotic-induced overgrowth of Clostridium difficile (although other bacteria may also cause this picture such as Staph. aureus, Salmonella, etc) in the large bowel which results in a potentially life threatening</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 11 Aug 2018 04:13:50 +0000</pubDate>
        </item>
        <item>
            <title>psilocybin (magic mushrooms)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psilocybin</link>
            <description>psilocybin (magic mushrooms)

see also:

	* toxicology
	* mushroom poisoning
	* novel psychoactive substances (NPS)

Introduction

	* psilocybin “magic mushrooms” are often used as psychedelic hallucinogens with relatively short duration of effects although these can cause severe serious psychological adverse effects, and rarely respiratory paralysis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 Dec 2025 21:54:02 +0000</pubDate>
        </item>
        <item>
            <title>psittacosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psittacosis</link>
            <description>psittacosis

see also:

	* respiratory medicine
	* pneumonia
	* hypersensitivity pneumonitis / bird fancier's lung / farmer's lung

Introduction

	* a form of pneumonia from contact with sick birds (eg. diarrhoea, not eating, ruffled feathers, watery eyes) infected by Chlamydia psittaci - usually by inhaled dried bird droppings or from kissing bird beaks or handling feathers</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 16 Dec 2020 02:36:19 +0000</pubDate>
        </item>
        <item>
            <title>psoriasis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psoriasis</link>
            <description>psoriasis

see also:

	* dermatology

Introduction

	* a chronic skin condition characterized by scaly hyperplastic areas of skin especially over extensor surfaces of joints such as elbows and knees but may be more widespread over the body as plaques or is some cases as pustular lesions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 12 Dec 2025 10:01:09 +0000</pubDate>
        </item>
        <item>
            <title>progressive supranuclear palsy (PSP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pspalsy</link>
            <description>progressive supranuclear palsy (PSP)

see also:

	* Parkinson's disease
	* neurology
	* bulbar palsy and pseudobulbar palsy

Introduction

	*  a rare tauopathy neurologic degenerative disease which is often initially misdiagnosed as Parkinson's disease
	*  the second most common tauopathy behind Alzheimer's disease
	*  first described by Richardson, Steele, and Olszewski in 1963 as a form of progressive parkinsonism</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Mar 2026 23:07:57 +0000</pubDate>
        </item>
        <item>
            <title>psychiatry and mental health</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psychiatry</link>
            <description>psychiatry and mental health

	* mental health history and examination
	* Mental Health Act 2014 Victoria
	* medical clearance of the acutely disturbed patient prior to transfer to a mental health facility
	* anorexia nervosa
	* anxiety disorders, panic attacks, hyperventilation
	* loneliness
	* depression
	* antidepressants
	* anti-psychotic medications
	* bipolar disorder
	* nature exposure and benefits to health
	* sedatives and hypnotics
	* benzodiazepines
	* fatigue
	* chronic fatigue syndr…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Mar 2026 23:14:33 +0000</pubDate>
        </item>
        <item>
            <title>psychoanalysis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psychoanalysis</link>
            <description>psychoanalysis

see also:

	* psychiatry and mental health
	* psychology
	* resources:
		* &lt;https://www.themarginalian.org/2014/06/09/adam-phillips-paul-holdengraber-interview/&gt;


“Psychoanalysis starts from the position that there is no cure, but that we need different ways of living with ourselves and different descriptions of these so-called selves.”

“The point is that it’s an experiment in what your life might be like if you speak freely to another person — speak and allow that person to sh…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Feb 2022 12:48:45 +0000</pubDate>
        </item>
        <item>
            <title>psychology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psychology</link>
            <description>psychology

see also:

	* psychiatry and mental health
	* stress
	* fatigue
	* Coping with shift work
	* sleep hygiene
	* insomnia
	* anxiety
	* regret and regret avoidance and decision making
	* social psychology</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 09 Feb 2022 21:35:46 +0000</pubDate>
        </item>
        <item>
            <title>psychosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psychosis</link>
            <description>psychosis

see also:

	* anti-psychotic medications
	* Mental state - delirium vs dementia vs psychosis
	* medical clearance of the acutely disturbed patient prior to transfer to a mental health facility
	* bipolar disorder
	* psychiatry and mental health

introduction

features that suggest an organic cause (ie. not a primary psychiatric cause)

	* clouding of consciousness
	* focal neurologic abnormality
	* inflammatory process - eg. febrile illness
	* systemic disease</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 04 Oct 2011 10:09:25 +0000</pubDate>
        </item>
        <item>
            <title>medical clearance of the acutely disturbed patient prior to transfer to a mental health facility</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psych_clearance</link>
            <description>medical clearance of the acutely disturbed patient prior to transfer to a mental health facility

see also:

	* psychiatry and mental health
	* Mental state - delirium vs dementia vs psychosis
	* the acutely confused patient
	* toxicology
	* ethanol intoxication/poisoning
	* neurology

introduction

	* the ED has an important role in ensuring patients are appropriately and safely admitted into mental health units.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 04 Oct 2011 08:39:33 +0000</pubDate>
        </item>
        <item>
            <title>fatigue</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psy_fatigue</link>
            <description>fatigue

see also stress; chronic fatigue syndrome; psychiatry and mental health; Coping with shift work; sleep hygiene, insomnia

Introduction:

	* fatigue can be defined as a pervasive sense of tiredness or lack of energy that is not related exclusively to exertion.
	* fatigue, like pain, is intrinsically a brain-mediated sensation, although, as with pain, people report that fatigue is experienced as a peripheral phenomenon, apparently occurring in musculoskeletal regions. Most patients also e…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 11 Feb 2024 06:51:58 +0000</pubDate>
        </item>
        <item>
            <title>fear</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psy_fear</link>
            <description>fear

see also:

	* psychiatry and mental health
	* psychology
	* prevent burnout, learn to reduce your stress and stressors
	* fatigue
	* stress
	* Coping with shift work
	* sleep hygiene
	* insomnia
	* anxiety
	* regret and regret avoidance and decision making

Introduction

	* fear is a critical evolutionary emotion that sharpens the mind and aims to reduce harm however, it can lead to either:
		*  anxiety
		*  anger - which tends to lead to actions which may not be well thought through and m…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 19 Apr 2024 00:17:30 +0000</pubDate>
        </item>
        <item>
            <title>regret and regret avoidance and decision making</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psy_regret</link>
            <description>regret and regret avoidance and decision making

see also:

	* psychology
	* neuropsychology of decision making

introduction

	* regret is an emotion associated with a decision that turns out badly.
	* it would appear that most animals, not just humans have neural pathways which process the emotion of regret, and that this has evolved as a powerful tool to modify behaviour and adapt to survive</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Jun 2014 06:14:05 +0000</pubDate>
        </item>
        <item>
            <title>shift work</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psy_shiftwork</link>
            <description>shift work

see also:

	* sleep hygiene
	* fatigue
	* stress
	* Wikipedia - shift work sleep disorder
	* insomnia
	* 16 tips to spot and help sleepy nurses
	* NSW Workcover - How to manage shift work (pdf)

introduction:

	* compared with non-shift workers, shift workers:
		* quality of sleep is poor:
		* they have less sleep
		* are more likely to suffer sleep disorders
		* are more likely to suffer from:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 26 Mar 2019 06:59:22 +0000</pubDate>
        </item>
        <item>
            <title>social psychology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psy_social</link>
            <description>social psychology

see also:

	* psychology

Introduction

Science

	* neurologic drive for social contact:
		*  amylin-responsive neurons in the central MPOA (cMPOA) are required for maternal motivation
		*  both parental care and female-female social contact depend on amylin and augment its expression</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 09 Feb 2022 21:40:08 +0000</pubDate>
        </item>
        <item>
            <title>stress</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psy_stress</link>
            <description>stress

see also:

	* psychiatry and mental health
	* psychology
	* prevent burnout, learn to reduce your stress and stressors
	* fatigue
	* fear
	* Coping with shift work
	* sleep hygiene
	* insomnia
	* anxiety
	* regret and regret avoidance and decision making
	* clinical burnout
	* post-traumatic stress syndrome (PTSD)
	* YOUR hospital's policies and procedures to assist with your stress or crisis management
	* The Guardian 2015: working from home including checking work emails increases stre…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 14 Mar 2025 00:02:18 +0000</pubDate>
        </item>
        <item>
            <title>Hospital policies and procedures for Mx of employee stress or crises</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psy_stress_hosp</link>
            <description>Hospital policies and procedures for Mx of employee stress or crises

see also stress; fatigue; coping with shift work

Hospital intranet documents

the following are generally only available within the hospital intranet:

Victoria

Western Health

	* Critical Incident Stress Management (CISM) (pdf)
	* Employee Assistance Plan (EAP) (pdf)
	* Employee Support and workplace relations policy (pdf)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 25 Oct 2008 00:19:41 +0000</pubDate>
        </item>
        <item>
            <title>prevent burnout, learn to reduce your stress and stressors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=psy_stress_mx</link>
            <description>prevent burnout, learn to reduce your stress and stressors

see also:

	* stress
	* clinical burnout
	* &lt;https://www.helpguide.org/articles/stress/stress-management.htm&gt;
	* How to stop worrying

coping strategies for ED staff:

short-term coping strategies:

	* increase the rewards from working:
		* our daily work offers us unique opportunities for rewards as directly caring for people who entrust us with their welfare is a very rewarding thing to be able to do. We are privileged to be able to o…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 17 Jul 2017 06:42:52 +0000</pubDate>
        </item>
        <item>
            <title>parathyroid hormone (PTH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pth</link>
            <description>parathyroid hormone (PTH)

see also:

	* calcitonin
	* vitamin D
	* calcium

Introduction

	* PTH is essential for life - excision of parathyroid glands =&gt; hypocalcaemic tetany =&gt; death;

Chemistry:

	* A linear 84 AA plypeptide (MW 9500) synthesised and secreted by the chief cells of the 4 parathyroid glands:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 05 Feb 2026 00:24:48 +0000</pubDate>
        </item>
        <item>
            <title>patient information sheets</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ptinfosheets</link>
            <description>patient information sheets

collections of fact sheets on the web

	* Vic. Better Health Channel
	* &lt;https://www.safercare.vic.gov.au/best-practice-improvement/clinical-guidance&gt;
	* Royal Children's Hospital paediatric fact sheets
	* The Children's Hospital at Westmead paediatric fact sheets
	* A-Z of infectious diseases (NSW DOH)
	* HealthInsite
	* Vic. DHS paediatric growth charts and child health record
	* Victorian North-East Valley Division GP's patient information sheets
	* Patient Handout…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 09:00:35 +0000</pubDate>
        </item>
        <item>
            <title>post-traumatic stress syndrome (PTSD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ptsd</link>
            <description>post-traumatic stress syndrome (PTSD)

see also:

	* stress

post-traumatic stress syndrome:

	* extreme emotionally stressful events may lead to delayed post-traumatic stress syndrome in susceptible people
	* this can be an intractable, difficult to treat condition where memories of a highly emotional event in the past keep flooding back, often triggered by similar emotional states, resulting in recurrent fear states and chronic psycho-somatic illness.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 17 Jul 2017 05:47:47 +0000</pubDate>
        </item>
        <item>
            <title>pentraxin 3 (PTX3)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ptx3</link>
            <description>pentraxin 3 (PTX3)

see also:

	* CRP - science and pathophysiology

Introduction

	* PTX3 is a member of the Pentraxin family of proteins which also includes CRP
		*  Short and long pentraxins share a 200-amino-acid-long C-terminal domain that contains a motif known as the pentraxin signature (HxCxS/TWxS)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Jul 2022 02:47:39 +0000</pubDate>
        </item>
        <item>
            <title>post-partum / puerperial complications</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=puerperium_complications</link>
            <description>post-partum / puerperial complications

see also:

	* ED Mx of 3rd stage of labour
	* massive blood transfusions
	* the shocked hypotensive patient
	* post-partum haemorrhage (PPH)

Introduction

	* most patients have an uneventful post partum course, but unfortunately many develop complications and issues which can create substantial impacts and in some cases can be life threatening.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 02 Oct 2018 04:48:36 +0000</pubDate>
        </item>
        <item>
            <title>pulmonary hypertension (PAH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pulmonary_hypertension</link>
            <description>pulmonary hypertension (PAH)

see also:

	* pulmonary fibrosis

introduction

	* defined as a mean pulmonary arterial pressure greater than 25 mm Hg at rest or greater than 30 mm Hg during exercise
	* characterized by a progressive and sustained increase in pulmonary vascular resistance that eventually leads to RVF and</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Jan 2014 07:35:29 +0000</pubDate>
        </item>
        <item>
            <title>pulmonary vein thrombosis (PVT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pulmv_thrombosis</link>
            <description>pulmonary vein thrombosis (PVT)

see also:

	* thrombosis
	* thrombophilia
	* pulmonary embolism (PE)
	* Cureus. 2017  Pulmonary Vein Thrombosis: A Recent Systematic Review

Introduction

	* pulmonary vein thrombosis is a rare and potentially life threatening condition with mortality rate dependent upon the aetiology
	* potential for cardiopulmonary complications such as:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Jun 2021 07:18:17 +0000</pubDate>
        </item>
        <item>
            <title>pulmonary fibrosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pulm_fibrosis</link>
            <description>pulmonary fibrosis

see also:

	* respiratory medicine

introduction

	* pulmonary fibrosis occurs due to a variety of diffuse parenchymal lung diseases (DPLDs)
	* generally causes a restrictive pattern of lung disease

aetiology

	* idiopathic pulmonary fibrosis
		* most present with a gradual onset, often greater than 6 months, of dyspnea and/or a nonproductive cough</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 24 Jan 2014 09:47:54 +0000</pubDate>
        </item>
        <item>
            <title>vaginal bleeding in early pregnancy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pvbleeding_earlypreg</link>
            <description>vaginal bleeding in early pregnancy

see also:

	* miscarriage
	* 2nd trimester miscarriage
	* gynaecology
	* pregnancy and risks of fetal loss
	* Rh isoimmunisation and Anti-D prophylaxis
	* Western Health early pregnancy assessment service (EPAS) referral process
	* DOH Victoria Guidelines on Mx of bleeding in early pregnancy 2011 (pdf)
	* patient information sheets:
		* Western Health ED - early pregnancy loss - Vietnamese version


Causes of vaginal bleeding in first 20 weeks of pregnancy:

…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 23 Feb 2022 02:06:08 +0000</pubDate>
        </item>
        <item>
            <title>PV bleeding in late pregnancy - abruption, placenta praevia, etc</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pvbleeding_latepreg</link>
            <description>PV bleeding in late pregnancy - abruption, placenta praevia, etc

see also:

	* Obstetrics
	* the shocked hypotensive patient
	* post-partum haemorrhage (PPH)

introduction

	* bleeding in the 2nd or 3rd trimesters of pregnancy requires:
		* resuscitation of the mother
		* assessment of fetal wellbeing
		* correction of coagulopathy if present</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 31 Jul 2013 10:13:47 +0000</pubDate>
        </item>
        <item>
            <title>post-op PV bleeding after LLETZ procedure to cervix</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pvbleed_lletz</link>
            <description>post-op PV bleeding after LLETZ procedure to cervix

see also:

	* menorrhagia / PV bleeding

Introduction

	* delayed onset heavy bright red PV bleeding several days to a week or so following LLETZ procedure to cervix may occur as a recognised infective complication with potential arterial bleeding</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 28 May 2017 11:30:05 +0000</pubDate>
        </item>
        <item>
            <title>peripheral vascular disease (PVD or PAD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pvd</link>
            <description>peripheral vascular disease (PVD or PAD)

see also:

	* wikipedia - PVD
	* acute limb ischaemia
	* vascular surgery

introduction

	* peripheral arterial disease (PAD or PVD) is a common problem in the middle aged and elderly who have atherosclerosis and primary prevention
	* the risk factors are the same as atherosclerosis and primary prevention
	* patients may present with:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 Apr 2012 13:58:46 +0000</pubDate>
        </item>
        <item>
            <title>acute pyelonephritis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pyelonephritis</link>
            <description>acute pyelonephritis

see also:

	* urinary tract infections (UTIs) / cystitis
	* renal abscesses and perinephric abscesses
	* renal colic
	* sepsis / septicaemia

introduction

	* acute pyelonephritis is a bacterial infection of the renal parenchyma
	* it usually arises from ascending bacteria in the urinary tract associated with urinary tract infections (UTIs) / cystitis
	* it is 5x more likely in females as males aged under 65 years</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 08 Apr 2024 12:50:38 +0000</pubDate>
        </item>
        <item>
            <title>Pyloric stenosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=pyloric_stenosis</link>
            <description>Pyloric stenosis

	* RCH guideline - pyloric stenosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 22:54:58 +0000</pubDate>
        </item>
        <item>
            <title>Q fever</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=qfever</link>
            <description>Q fever

see also:

	* zoonoses
	* NSW Govt fact sheet
	* CDC Information Q Fever

Introduction

	* Q fever is a zoonosis caused by Coxiella burnetii, an obligate gram-negative intracellular bacterium which primarily infects cattle, sheep and goats as the primary reservoirs but other animals including wild animals may be reservoirs</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 31 Mar 2018 00:15:25 +0000</pubDate>
        </item>
        <item>
            <title>quality, adverse events, reporting and standards</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=quality</link>
            <description>quality, adverse events, reporting and standards

	* Clinical Practice Guidelines Portal
	* Quality use of Medicines in Australian Hospitals
	* Australian Commission on Safety and Quality Health Care - safe ePrescribing and electronic medication management (EMM)
	* Australian National Inpatient Medication Chart (NIMC)
	* NEHTA - National E-Health Transition Authority
		* NEHTA - Clinical Knowledge Manager - development of standardised data for eHealth systems

	* Australian Council on Healthcare…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Dec 2022 03:12:08 +0000</pubDate>
        </item>
        <item>
            <title>quetiapine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=quetiapine</link>
            <description>quetiapine

see also:

	* anti-psychotic medications

Introduction

	* quetiapine is an atypical benzothiazepine antipsychotic agent introduced in the late 1990's.
	* it is an antagonist at multiple neurotransmitter receptors in the brain.
	* it has been proposed that it's  antipsychotic  activity is mediated through a combination of dopamine type 2 (D2) and serotonin type 2 (5-HT2) antagonism</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 08 Sep 2020 11:42:47 +0000</pubDate>
        </item>
        <item>
            <title>quinine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=quinine</link>
            <description>quinine

see also:

	* acute kidney injury (AKI) / acute renal failure (ARF)

Introduction

	* quinine has a long history of medical usage as well as an additive to drinks to give a bitter taste as in tonic water and lemon, lime bitters
	* it is possible that consumption of quinine as tonic water could create immune sensitivity to oral doses of quinine</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 12 Jul 2023 02:39:48 +0000</pubDate>
        </item>
        <item>
            <title>flouroquinolone antibiotics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=quinolones</link>
            <description>flouroquinolone antibiotics

see also:

	* antibiotics

introduction

	* synthetic fluorinated analogues of nalidixic acid (see under urinary antiseptics)
	* active against a variety of Gram -ves &amp; +ves by inhib. of DNA gyrase
	* activity includes Enterobacteriacaea, Pseudomonas, Neisseria, and at higher levels, Staph, Legionella, Chlamydia &amp; some mycobacteria with anaerobes being less susceptible.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 05:19:07 +0000</pubDate>
        </item>
        <item>
            <title>peritonsillar abscess (quinsy)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=quinsy</link>
            <description>peritonsillar abscess (quinsy)

see also:

	* tonsillitis

introduction

	* a common complication of bacterial tonsillitis

Mx

	* admit to ED observation unit or inpatient unit under ENT
	* general Mx as per tonsillitis
	* arrange aspiration of abscess

aspiration of abscess

	* usually this is performed by ENT</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 25 Jul 2014 07:06:17 +0000</pubDate>
        </item>
        <item>
            <title>rabies and related lyssaviruses</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rabies</link>
            <description>rabies and related lyssaviruses

see also:

	* animal bites in Australia
	* travel medicine
	* rabies by country:
		* &lt;https://www.gov.uk/government/publications/rabies-risks-by-country/rabies-risks-in-terrestrial-animals-by-country#a-to-z-of-countries&gt;
		* &lt;https://www.cdc.gov/rabies/country-data/index.html&gt;

	* &lt;https://immunisationhandbook.health.gov.au/contents/vaccine-preventable-diseases/rabies-and-other-lyssaviruses&gt; - Australian immunisation handbook guidelines on rabies and related lyss…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 10 Jan 2026 21:18:12 +0000</pubDate>
        </item>
        <item>
            <title>radial nerve palsy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=radialnpalsy</link>
            <description>radial nerve palsy

see also:

	* paraesthesiae or numbness

introduction

	* atraumatic radial nerve palsy is usually due to prolonged pressure on the nerve as it passes around the humeral mid-shaft
	* the most common cause is the intoxicated patient sleeping on a chair with their arm over the back of the chair</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 14 Aug 2013 04:16:20 +0000</pubDate>
        </item>
        <item>
            <title>Radiation emergencies</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=radiation_emergencies</link>
            <description>Radiation emergencies

see also  radiation injury, ionising radiation, management summary, disaster medicine

Summary

	* a person or object exposed to radiation does not make them radioactive
	* a person or object contaminated by radioactive material whether on the skin or ingested, does become radioactive, although the   risk to others is very small if adequate precautions are taken</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 Sep 2020 02:43:28 +0000</pubDate>
        </item>
        <item>
            <title>Mx of radiation emergencies - summary</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=radiation_emergencies_mxsummary</link>
            <description>Mx of radiation emergencies - summary

see ionising radiation, radiation emergencies - details, disaster medicine

	* DON'T PANIC

Mx overview for a radiation emergency at a hospital in Victoria:

	* inform ED consultant &amp; nursing supervisor &amp; activate medical DISPLAN if appropriate
	* ensure DHS &amp; Radiation Safety Program (RSP) is notified ph: 13 22 22</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Oct 2008 00:27:39 +0000</pubDate>
        </item>
        <item>
            <title>radiation injury</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=radiation_injury</link>
            <description>radiation injury

see also:

	* ionising radiation
	* oncology
	* radiation emergencies
	* polonium poisoning
	* tardigraves repair ionising radiation damage by substantially increasing DNA repair proteins which allows them to survive radiation levels 1000x greater than humans can survive 

Radiation syndromes:

haemopoietic syndrome:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 17 Apr 2024 10:03:09 +0000</pubDate>
        </item>
        <item>
            <title>Ionising radiation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=radiation_ionising</link>
            <description>Ionising radiation

see also:

	*  oncology
	*  radiology
	*  fetal radiation doses in pregnancy Xrays and CT scans
	*  radiation injury
	*   radiation emergencies
	*  &lt;https://www.quora.com/What-happened-to-the-radiation-that-was-supposed-to-last-thousands-of-years-in-Hiroshima-1945/answer/C-Stuart-Hardwick&gt;
	*  electromagnetic field (EMF) health hazards

Radio-active decay:

	* radioactive material is composed of atoms that are radioactive which means their nuclei are unstable in an high energ…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 13 Aug 2025 13:06:55 +0000</pubDate>
        </item>
        <item>
            <title>radiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=radiology</link>
            <description>radiology

see also:

	* online radiology image banks - interesting Xrays, etc
	* Radiology Info - Radiological Society of Nth America's radiology information website
	* radiologyED.org resource library - links to useful websites
	* Radiopedia CT course Das Smacc 2017
	* Arch Intern Med. 2009 Dec 14; 169(22): 2078–2086. Radiation Dose Associated with Common Computed Tomography Examinations and the Associated Lifetime Attributable Risk of Cancer
	* Radiation risks and cancer risk
	* ionising radi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 19 Jul 2023 06:17:30 +0000</pubDate>
        </item>
        <item>
            <title>online radiology image banks</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=radiology_image_banks</link>
            <description>online radiology image banks

see also:

	* radiology

emergency medicine oriented radiology image banks

	* LIFTL radiology images - normal
	* LITFL radiology images - abnormals
	* EMRbank.org - UK Emergency Medicine interesting Xray upload website</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 21 Dec 2011 13:08:56 +0000</pubDate>
        </item>
        <item>
            <title>raised intracranial pressure (ICP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=raised_icp</link>
            <description>raised intracranial pressure (ICP)

see also:

	* the comatose patient
	* headache
	* stroke (CVA)

introduction

	* raised ICP may cause fatal further cerebral injury, and thus in those patients at risk, it should be considered as a possible complication and actively managed.
	* raised ICP may result in decreased blood perfusion of the brain</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 May 2014 02:04:44 +0000</pubDate>
        </item>
        <item>
            <title>retinal artery occlusion (RAO)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rao</link>
            <description>retinal artery occlusion (RAO)

see also:

	* ophthalmology
	* the patient with acute blurred vision or visual loss / blindness

introduction

	* sudden onset of relatively painless monocular vision due to ischaemia/infarction of the retina resulting from occlusion of central retinal artery blood flow which comes from the ophthalmic artery which is the 1st intracranial branch of the internal carotid artery although 14% have a cilioretinal artery anatomy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Jun 2018 06:59:36 +0000</pubDate>
        </item>
        <item>
            <title>acute rashes in adults</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rash_adults</link>
            <description>acute rashes in adults

see also:

	* paediatric exanthems
	* localised rashes

General approach to diagnosis

1. is the patient in shock or having trouble breathing? - immediate resuscitation as required

	* consider:
		*  anaphylaxis with/without typical urticaria
		*  septic shock including meningococcal septicaemia, staph scalded skin syndrome, etc</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 11 Jul 2022 08:56:43 +0000</pubDate>
        </item>
        <item>
            <title>bullous / blistering rashes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rash_bullous</link>
            <description>bullous / blistering rashes

see also:

	* dermatology
	* vesicular rashes
	* skin necrosis

introduction

	* bullous rashes are those with large fluid filled superficial cutaneous bullae

types of lesions

	* Nikolsky sign
		* applying lateral pressure to an area of normal appearing skin or mucosa causes formation of a blister</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 17 Oct 2015 11:37:58 +0000</pubDate>
        </item>
        <item>
            <title>facial rashes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rash_facial</link>
            <description>facial rashes

see also:

	* dermatology
	* non-traumatic facial swelling / oedema
	* DermNet NZ: facial rashes index

acute rashes only affecting the face

	* herpes zoster (shingles) - dermatomal to one side only
	* Herpes simplex virus (HSV)
	* angular cheilitis
	* circum-oral irritant dermatitis from saliva
	* tinea corporis may just involve the face
	* molluscum contagiosum may just involve an area of the face</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Jul 2022 06:48:27 +0000</pubDate>
        </item>
        <item>
            <title>acute generalized non-vesicular non-purpuric rashes covering most parts of the body</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rash_generalised</link>
            <description>acute generalized non-vesicular non-purpuric rashes covering most parts of the body

see also:

	* dermatology
	* localised rashes
	* paediatric exanthems
	* &lt;https://www.aafp.org/afp/2010/0315/p735.html&gt;

DDx

	* hypersensitivity reactions
		*  urticaria
		*  erythema multiforme
		*  drug eruption
			*  morbilliform drug reaction
			*  drug reactions with eosinophilia and systemic symptoms (</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 29 Mar 2026 11:21:28 +0000</pubDate>
        </item>
        <item>
            <title>the linear skin lesion or rash</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rash_linear</link>
            <description>the linear skin lesion or rash

see also:

	* dermatology

introduction

	* the finding of linear skin lesions can often assist in the diagnosis of skin rashes as the list of differentials tends to be more limited.

DDx

striae

	* striae distensia

dermographism</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Oct 2023 05:20:34 +0000</pubDate>
        </item>
        <item>
            <title>localised rashes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rash_local</link>
            <description>localised rashes

see also:

	* facial rashes
	* the linear skin lesion or rash
	* paediatric exanthems
	* acute rashes in adults

Usually self-evident acute skin pathology

	* physical trauma - bruises, etc
	* thermal burns
	* chemical caustic burns - acids, alkalis, skin irritants
	* radiation burns
	* prolonged exposure to a direct heat source giving the classical reticular</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 26 Mar 2026 23:01:38 +0000</pubDate>
        </item>
        <item>
            <title>papular rashes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rash_papular</link>
            <description>papular rashes

see also:

	* dermatology
	* pustular rashes
	* the petechial rash / purpura
	* the linear skin lesion or rash
	* facial rashes
	* acute generalized non-vesicular non-purpuric rashes covering most parts of the body
	* skin nodular &quot;rash&quot;

Introduction

	* papules are palpable, elevated skin lesions &lt; 1cm in diameter and may be elevated due to thickened epidermis (scaly) or infiltration of dermis by cells or deposits (smooth)

Smooth papules in adults</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 29 Nov 2023 05:39:25 +0000</pubDate>
        </item>
        <item>
            <title>the petechial rash / purpura</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rash_petechial</link>
            <description>the petechial rash / purpura

see also:

	* dermatology
	* Fever with petechial or purpuric rash

introduction

	* purpura is visible bleeding into the skin or mucous membranes which is non-blanching when pressure is applied

	* the patient with an acute petechial or purpuric rash should be immediately considered for the life threatening emergency of meningococcal septicaemia, particularly if they are unwell or febrile - see</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 29 Nov 2023 04:54:16 +0000</pubDate>
        </item>
        <item>
            <title>pustular rashes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rash_pustular</link>
            <description>pustular rashes

see also:

	* dermatology

Introduction

	* pustule is a pus filled lesion &lt; 1cm diameter usually filled with neutrophils
	* it may be infected or sterile

Pustular eruptions in adults

DDx

	* follicular (centred on hair follicle units):
		*  folliculitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 29 Nov 2023 05:31:51 +0000</pubDate>
        </item>
        <item>
            <title>vesicular rashes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rash_vesicular</link>
            <description>vesicular rashes

see also:

	* dermatology
	* bullous / blistering rashes

introduction

	* vesicular rashes are those with small fluid filled superficial cutaneous vesicles

DDx

	* Herpes simplex virus (HSV)
		*  localised
		*  more disseminated as in eczema herpeticum

	* varicella-zoster virus (chickenpox/shingles)
	* herpes zoster (shingles)
	* pompholyx
	* tinea
	* dermatitis herpetiformis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Feb 2025 22:34:14 +0000</pubDate>
        </item>
        <item>
            <title>renin-angiotensin system inhibitors (RAS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rasinhib</link>
            <description>renin-angiotensin system inhibitors (RAS)

see also:

	* angiotensin
	* renin

Introduction

	* renin-angiotensin system inhibitors are widely used to Rx hypertension and heart failure with reduced ejection fraction (HFrEF) and include:
		*  ACE inhibitors
		*  angiotensin II receptor blockers (ARBs)
		*  angiotensin receptor–neprilysin inhibitors (ARNIs) - now preferred for heart failure with reduced ejection fraction (HFrEF)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 03:59:43 +0000</pubDate>
        </item>
        <item>
            <title>Raynaud's phenomenon</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=raynauds</link>
            <description>Raynaud's phenomenon

see also:

	* rheumatology

introduction

	* recurrent vasospasm of fingers and toes (may also affect ears, tip of nose) resulting in pallor, cyanosis, then erythema and a sense of fullness, in response to cold exposure
	* 80-90% are “primary Raynaud's disease</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 10 May 2023 12:23:50 +0000</pubDate>
        </item>
        <item>
            <title>red back spider bites / Latrodectism</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=redback_spider</link>
            <description>red back spider bites / Latrodectism

see also:

	* spider bites in Australia
	* anaphylaxis

introduction

	* the red back spider ((L hasselti)) belongs to the widow spider family (Latrodectus sp.) and are a common cause of spider bite in Australia with 3,000-5,000 bites per annum which result in Latrodectism which is primarily due to neurotoxins such as alpha latrotoxin</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 21 Feb 2020 23:20:06 +0000</pubDate>
        </item>
        <item>
            <title>acute atraumatic painful red eye(s)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=redeye</link>
            <description>acute atraumatic painful red eye(s)

see also:

	* ophthalmology
	* Eye injuries
	* the patient with acute blurred vision or visual loss / blindness

Introduction

	* there are a range of non-traumatic possibilities, some of which are potentially vision threatening such as glaucoma or uveitis
	* note that the patient may not be aware of a trauma, hence examination should include looking for foreign body, eye trauma</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Jun 2025 06:25:33 +0000</pubDate>
        </item>
        <item>
            <title>tick-induced mammalian red meat allergy (MMA) / alpha-gal syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=redmeat_allergy</link>
            <description>tick-induced mammalian red meat allergy (MMA) / alpha-gal syndrome

see also:

	* ticks in Australia
	* allergy and hypersensitivity reactions
	* anaphylaxis
	* &lt;https://www.mydr.com.au/allergy/mammalian-meat-allergy&gt;

Introduction

	* some people develop a food allergy with potential anaphylaxis some months after a tick bite
	* aka alpha-gal syndrome
	* the allergy is to a sugar, galactose-α-1,3-galactose (α-gal), which is found in mammalian red meat other than Old World monkeys, apes and human…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Oct 2025 23:25:15 +0000</pubDate>
        </item>
        <item>
            <title>refeeding syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=refeeding</link>
            <description>refeeding syndrome

see also:

	* alcohol dependence
	* starvation
	* anorexia nervosa
	* geriatrics

Introduction

	* Refeeding syndrome consists of adverse metabolic effects that occur when a starved or malnourished individual re-commences feeding, particularly with carbohydrate.

Clinical features

	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:45:46 +0000</pubDate>
        </item>
        <item>
            <title>louse-borne relapsing fever</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=relapsing_fever</link>
            <description>louse-borne relapsing fever

see also:

	* clinically important bacteria
	* Lyme disease
	* tick-borne relapsing fever

Introduction

	* caused by Borrelia recurrentis which evolved to spread via the human louse rather than ticks as is the case with other Borrelia sp. presumably in response to higher density living of the Neolithic period</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 May 2025 06:49:04 +0000</pubDate>
        </item>
        <item>
            <title>Relaxin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=relaxin</link>
            <description>Relaxin

see also gynaecology

Introduction

	* Polypeptide similar to insulin, controlled by 2 gene sites, mainly produced by corpus luteum of pregnancy, but also by chorion &amp; decidua.
	* Levels rise early in 1st TM &amp; stay high until mid-pregnancy &amp; become very high during labour &amp; become almost indetectable within 3 days post-partum;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 01 Nov 2008 04:35:31 +0000</pubDate>
        </item>
        <item>
            <title>Rural and remote medicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=remote_medicine</link>
            <description>Rural and remote medicine

	* Australian College of Rural and Remote Medicine

Australian Antarctic Division

	* Australian Antarctic Division website
	* employ doctors for 3 or 9 month positions depending on whether just 3 month Summer or a 9 month Winter stint.
	* opportunities also to be stationed at Macquarie Island - no icebergs but lots of penguins and isolation.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 05 Dec 2008 23:44:19 +0000</pubDate>
        </item>
        <item>
            <title>renal medicine (nephrology)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=renal</link>
            <description>renal medicine (nephrology)

	* Help prevent AKI in the ED:
		*  withhold ACEIs, ARBs, diuretics, sulfonylureas, metformin, SGLT2 inhibitors in patients with dehydration or hypotension
		*  avoid NSAIDs in patients or combined ACEIs/ARBs and diuretics especially if dehydrated</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2025 06:48:35 +0000</pubDate>
        </item>
        <item>
            <title>renal artery aneurysm</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=renala_aneurysm</link>
            <description>renal artery aneurysm

see also:

	* splenic artery aneurysm
	* Left upper quadrant abdominal pain in the ED
	* the patient with acute RUQ pain in ED

Introduction

	*  these are rare (0.1% of the population in autopsy studies), usually present in hypovolaemic shock with abdominal pain, but may also have haematuria or urinary obstruction
		* rupture occurs in 3-5% with these aneurysms and has a 10% mortality, thus rupture prevalence and mortality rates are much lower than with splenic artery ane…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 06 Aug 2022 01:18:50 +0000</pubDate>
        </item>
        <item>
            <title>renal abscesses and perinephric abscesses</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=renal_abscess</link>
            <description>renal abscesses and perinephric abscesses

see also:

	* renal masses and cysts
	* acute pyelonephritis
	* tuberculosis (TB)
	* lymphoma
	* renal infarct / infarction

introduction

	* renal abscesses and perinephric abscesses generally present as flank pain with fever and markedly raised inflammatory markers such as C reactive protein (CRP)
	* they may present insidiously, particularly in the elderly, diabetcis or chronic alcoholism who may have autonomic neuropathy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 27 Mar 2018 01:10:39 +0000</pubDate>
        </item>
        <item>
            <title>renal colic</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=renal_colic</link>
            <description>renal colic

see also:

	* urology
	* flank pain
	* back pain
	* urolithiasis / renal stones / renal calculi
	* Vic DHS Fact Sheet - kidney stones / renal colic (pdf)
	* Qld health patient information for renal stones including dietary advice (pdf)
	* European Assoc Urology - urolithiasis
	* osteopaths show rear seat roller coaster rides may result in passage of stones in modelling
	* WH obstructive urosepsis / emergency nephrostomy guideline (doc) - WH intranet only

introduction

	* renal coli…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2025 05:48:00 +0000</pubDate>
        </item>
        <item>
            <title>renal masses and cysts</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=renal_cysts</link>
            <description>renal masses and cysts

see also:

	* polycystic kidney disease
	* renal malignancies
	* renal medicine (nephrology)
	* renal abscesses and perinephric abscesses

introduction

	* it is common to have an incidental finding of cysts on kidneys on a CT KUB or CT abdo scan
	* some should have a renal USS to further elucidate their nature and determine whether the patient should be referred to</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Apr 2014 03:58:41 +0000</pubDate>
        </item>
        <item>
            <title>renal infarct / infarction</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=renal_infarct</link>
            <description>renal infarct / infarction

see also:

	* renal masses and cysts
	* renal abscesses and perinephric abscesses
	* acute pyelonephritis

aetiology

	* embolic (~60%)
		* over 80% of these are due to atrial fibrillation - renal infarction may be the 1st presentation of AF
		* cardiomyopathy
		* artificial heart valve thrombi
		* septic emboli - infective endocarditis (including SBE)

	* renal artery trauma (~8%)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 04 Sep 2021 03:19:14 +0000</pubDate>
        </item>
        <item>
            <title>renal physiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=renal_phys</link>
            <description>renal physiology

see also:

	* renal medicine (nephrology)
	* physiology main index

...coming...</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jan 2009 06:24:16 +0000</pubDate>
        </item>
        <item>
            <title>renin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=renin</link>
            <description>renin

see also:

	* angiotensin
	* aldosterone
	* ACE inhibitors



image courtesy of wikipedia

introduction

	* renin is a peptide which converts circulating inactive angiotensinogen (a globulin produced by the liver) to inactive angiotensin I which is then converted to active angiotensin II by ACE.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 11 May 2014 11:23:19 +0000</pubDate>
        </item>
        <item>
            <title>respiratory medicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=respiratory</link>
            <description>respiratory medicine

see also:

	* the chest X-ray (CXR)
	* spirometry lung function tests
	* acute dyspnoea / shortness of breath (SOB)
	* the persistent cough
	* hypoxia
	* Acute Respiratory Distress Syndrome (ARDS)
	* e-cigarette or vaping pulmonary injury
	* paediatric asthma
	* asthma
	* chronic obstructive pulmonary disease (COPD)
	* Mx of the wheezy elderly patient - acute pulmonary oedema versus asthma
	* bronchiolitis
	* croup
	* pneumonia
	* bronchiectasis
	* home oxygen
	* pleural ef…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 12 Sep 2021 01:36:56 +0000</pubDate>
        </item>
        <item>
            <title>use of mechanical restraints</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=restraint</link>
            <description>use of mechanical restraints

see also:

	* managing violence or the aggressive patient in the ED
	* rapid sedation of the agitated or aggressive patient in the ED
	* Mental Health Act 2014 Victoria
	* Vic. Chief Psychiatrist's Guideline. Mechanical Restraint. 2006.
	* Australian Society for Geriatric Medicine. Position Statement No. 2: Mechanical Restraint Use in Older People. Revised September 2012
	* Department of Health &amp; Ageing, Australian Government.  Decision making tool – Responding to i…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 08 Feb 2026 01:56:42 +0000</pubDate>
        </item>
        <item>
            <title>Resuscitation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=resus</link>
            <description>Resuscitation

see also:

	* neonatal resuscitation
	* choking / respiratory arrest / cardiac arrest / BLS / ALS / CPR
	* trauma
	* burns
	* toxicology</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Oct 2023 06:18:33 +0000</pubDate>
        </item>
        <item>
            <title>resuscitative thoracotomy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=resuscitative_thoracotomy</link>
            <description>resuscitative thoracotomy

see also:

	* trauma to the chest
	* massive blood transfusions
	* LITFL - emergency thoracotomy
	* King's Cross ER - thoractomy for stab victim - great video

introduction

	* survival rates of resuscitative thoracotomy:
		* blunt chest trauma has a survival rate following cardiac arrest of only 1-2%
		* blunt chest trauma with pericardial tamponade on</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 23 Dec 2014 05:47:27 +0000</pubDate>
        </item>
        <item>
            <title>retinal detachment</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=retinal_detachment</link>
            <description>retinal detachment

see also:

	* ophthalmology
	* the patient with acute blurred vision or visual loss / blindness

introduction

	* retinal detachment occurs by 3 main mechanisms:
		* rhegmatogenous retinal detachment
			* most common form
			* break in the neuronal layer with resultant leakage of vitreous between the retinal layers causing separation of the layers</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 02 Mar 2026 05:31:21 +0000</pubDate>
        </item>
        <item>
            <title>retrobulbar haemorrhage</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=retrobulbar_haemorrhage</link>
            <description>retrobulbar haemorrhage

see also:

	* ophthalmology
	* RVEEH clinical practice guidelines:
		* Retrobulbar Haemorrhage (pdf)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Oct 2018 03:50:18 +0000</pubDate>
        </item>
        <item>
            <title>retroperitoneal fibrosis (RPF)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=retroperitoneal_fibrosis</link>
            <description>retroperitoneal fibrosis (RPF)

see also:

	* CT abdomen

Introduction

	* an uncommon disease characterized by a fibrous reaction that takes place in the peri-aortic retroperitoneum and often entraps the ureters causing obstructive uropathy or compression of the IVC</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Jun 2025 03:19:22 +0000</pubDate>
        </item>
        <item>
            <title>retroperitoneal haemorrhage</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=retroperitoneal_haemorrhage</link>
            <description>retroperitoneal haemorrhage

see also:

	* The adult with back pain in the ED

Introduction

	* retroperitoneal bleeding can be life threatening and often diagnosis is delayed

Clinical features

	* flank pain - often of sudden onset
	* if forms a large psoas haematoma, may present with:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 Jan 2018 14:57:26 +0000</pubDate>
        </item>
        <item>
            <title>rheumatoid arthritis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rha</link>
            <description>rheumatoid arthritis

see also:

	* rheumatology
	* arthritis - clinical patterns
	* rheumatoid factor
	* autoimmune disease

epidemiology

	* F:M = 3:1; esp. 4th-6th decades; 20% have an acute presentation; inflammation increased by movement!
	* esp. if HLA-DR4; Rh factor +ve in 70%;
	* US study of 76,000 women aged 50-79 years presented in 2010</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 Feb 2024 07:49:57 +0000</pubDate>
        </item>
        <item>
            <title>rhabdomyolysis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rhabdomyolysis</link>
            <description>rhabdomyolysis

introduction

	* skeletal muscle necrosis may cause death either by:
		* releasing heme pigments such as myoglobin into the circulation which may result in acute renal failure, particularly if there is hypovolaemia and poor renal flow.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 14 Nov 2021 04:32:32 +0000</pubDate>
        </item>
        <item>
            <title>rheumatology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rheumatology</link>
            <description>rheumatology

see also:

	* non-steroidal anti-inflammatory drugs (NSAIDs)
	* gout
	* systemic lupus erythematosus (SLE)
	* Sjögren's syndrome (SS)
	* osteomyelitis and septic arthritis
	* rheumatoid arthritis
	* ankylosing spondylitis (AS)
	* the swollen joint and its diagnostic workup
	* assessment of joint function and arthritis severity
	* arthritis - clinical patterns
	* extra-articular clinical features of rheumatologic conditions
	* polymyalgia rheumatica
	* polymyositis (PM)
	* dermatomy…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 03 Jul 2024 11:54:10 +0000</pubDate>
        </item>
        <item>
            <title>rheumatoid factor</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rhfactor</link>
            <description>rheumatoid factor

see also:

	* the swollen joint and its diagnostic workup
	* rheumatoid arthritis
	* arthritis - clinical patterns

introduction

	* rh factor is a blood test often used in assessment of patients with arthritis
	* this test is NOT useful for screening:
		* it is nonspecific and insensitive - the presence of rheumatoid factor does not indicate rheumatoid arthritis, nor does its absence rule out rheumatoid arthritis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Dec 2015 04:16:09 +0000</pubDate>
        </item>
        <item>
            <title>rhinitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rhinitis</link>
            <description>rhinitis

see also:

	* sinusitis
	* coryza / the common cold / viral rhinopharyngitis / rhinitis

introduction

	* viral rhinitis (eg. Common Cold virus) and allergic rhinitis are very common causes of rhinitis
	* autonomic stimuli have a greater effect on patients with nonallergic rhinitis than on those with allergic rhinitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 06 Oct 2025 22:20:16 +0000</pubDate>
        </item>
        <item>
            <title>Rh isoimmunisation and Anti-D</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rh_isoimm</link>
            <description>Rh isoimmunisation and Anti-D

see also gynaecology

	* Aust. Red Cross website with info. on blood products including Anti-D
	* RANZCOG guidelines for use of Anti-D (pdf)
	* Aust. Red Cross guidelines on use of Rh Anti-D (2024) (pdf)
	* Western Health guideline (docx) - intranet only

Introduction

	* women who are Rh -ve and are pregnant are at risk of developing Rh iso-immunisation which is the development of permanent maternal antibodies against fetal Rh +ve red blood cell markers. Once this…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 26 Jul 2025 04:47:17 +0000</pubDate>
        </item>
        <item>
            <title>rifampicin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rifampicin</link>
            <description>rifampicin

see also:

	* antibiotics

introduction

	* rifampicin is a rifamycin antibiotic which inhibits DNA dependent RNA polymerase activity in susceptible cells
	* it is mainly used for:
		* Rx of tuberculosis (TB)
		* Rx of leprosy
		* prophylaxis for meningitis and Haemophilus influenza type B

	* particularly active against rapidly growing extracellular organisms</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Apr 2014 04:18:54 +0000</pubDate>
        </item>
        <item>
            <title>removing a ring from a finger</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ring_removal</link>
            <description>removing a ring from a finger

introduction

	* removing a ring from a finger of and injured wrist/hand/finger is one of those important, common ED procedures to prevent the ring trapping oedema distally to it and then causing ischaemic necrosis of the finger.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 Jan 2015 10:05:00 +0000</pubDate>
        </item>
        <item>
            <title>risk and the perception of risk</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=risk</link>
            <description>risk and the perception of risk

see also:

	* air pollution and health risks

Introduction

	* emergency medicine is for the most part, an art form, a careful balancing of a multitude of concurrent risks, benefits, uncertainty and probabilities which the general population struggle to comprehend</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 07 Jul 2020 14:06:06 +0000</pubDate>
        </item>
        <item>
            <title>risk factor and treatment benefit metrics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=risk_factor_metrics</link>
            <description>risk factor and treatment benefit metrics

see also:

	* epidemiology

risk of causing an event

absolute risk

absolute risk = (Event rate in those exposed - Event rate in those not exposed)

relative risk

relative risk = (Event rate in those exposed - Event rate in those not exposed) / (Event rate in those NOT exposed)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Apr 2020 02:23:21 +0000</pubDate>
        </item>
        <item>
            <title>rivaroxaban</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rivaroxaban</link>
            <description>rivaroxaban

see also:

	* anticoagulants
	* warfarin
	* enoxaparin
	* apixaban
	* dabigatran

introduction

	* introduced in Australia in 2009 as Xarelto, initially on PBS for post-op THR patients but in 2013, this was expanded to include Rx of PE and/or DVT.
	* an orally active Factor Xa inhibitor</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Mar 2026 04:54:09 +0000</pubDate>
        </item>
        <item>
            <title>rocuronium</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rocuronium</link>
            <description>rocuronium

see also:

	* neuro-muscular blockers
	* rapid sequence induction (RSI) for emergency intubation

introduction

	* a non-depolarising competitive acetylcholine antagonist at nicotinic receptors
	* a commonly used non-depolarising neuromuscular blocking agent (NMBA) in the ED for induction when suxamethonium contra-indicated.
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 13 Mar 2015 04:47:15 +0000</pubDate>
        </item>
        <item>
            <title>acne rosacea</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rosacea</link>
            <description>acne rosacea

see also:

	* DermNet NZ: rosacea
		* Aust. College Dermatologists - Rosacea
		* National Rosacea Organisation

Introduction

	* chronic inflammatory red rash mainly involves the central face in 30-80 yr olds but can arise in younger patients
	* 10% of population develop rosacea and of these, 60% develop ocular rosacea
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 07 Jul 2017 07:57:37 +0000</pubDate>
        </item>
        <item>
            <title>return of spontaneous circulation (ROSC) post-arrest</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rosc</link>
            <description>return of spontaneous circulation (ROSC) post-arrest

see also:

	* choking / respiratory arrest / cardiac arrest / BLS / ALS / CPR
	* cardiac arrhythmias
	* bradycardia
	* the shocked hypotensive patient

Introduction

	* this applies to patients who have been revived from choking / respiratory arrest / cardiac arrest / BLS / ALS / CPR or ventricular fibrillation (VF) and have attained return of spontaneous circulation (ROSC)
	* an important early consideration is understanding the patient's li…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 05 Jan 2019 07:13:34 +0000</pubDate>
        </item>
        <item>
            <title>Ross River virus (RRV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rossrivervirus</link>
            <description>Ross River virus (RRV)

see also:

	* zoonoses
	* Barmah Forest virus (BFV)
	* Murray Valley encephalitis (MVE)
	* Japanese encephalitis virus (JEV)
	* viruses

Introduction

	* mosquito-borne viral infection causing epidemic polyarthritis
	* no evidence of transmission from person to person as transmission requires a female mosquito vector
	* infection with the RRV confers lifelong immunity</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 20 Dec 2025 14:01:00 +0000</pubDate>
        </item>
        <item>
            <title>acute rotator cuff tear</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rotatorcufftear</link>
            <description>acute rotator cuff tear

see also:

	* orthopaedics in the ED
	* the painful shoulder
	* references:
		* BMJ 2017
		* Austin Health guidelines (pdf)
		* Western Health Phong Tran's website


Introduction

	* acute shoulder rotator cuff tears can result in significant pain and disability
	* these should be managed more acutely than the more subacute/chronic rotator cuff syndrome conditions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 03 Sep 2018 03:22:54 +0000</pubDate>
        </item>
        <item>
            <title>rapid sequence induction (RSI) for emergency intubation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rsi</link>
            <description>rapid sequence induction (RSI) for emergency intubation

see also:

	* anaesthetics
	* emergency intubation
	* induction agents for anaesthesia
	* neuro-muscular blockers
	* assisted ventilation
	* Mx of the newly intubated patient in ED - post-intubation
	* nasogastric tube insertion
	* Western Health's intubation video on Vimeo

Introduction

	* RSI is the almost simultaneous administration of an induction agent and a neuromuscular blocking agent to induce unconsciousness and neuromuscular par…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:54:05 +0000</pubDate>
        </item>
        <item>
            <title>human respiratory syncytial virus / human orthopneumovirus (HRSV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rsv</link>
            <description>human respiratory syncytial virus / human orthopneumovirus (HRSV)

see also:

	* viruses
	* influenza
	* &lt;https://www.rch.org.au/kidsinfo/fact_sheets/Respiratory_Syncytial_Virus_RSV/&gt;
	* &lt;https://www.health.nsw.gov.au/Infectious/factsheets/Pages/Respiratory-syncytial-virus.aspx&gt;

Introduction

	* now renamed to human orthopneumovirus
	* it is a negative-sense, single-stranded RNA virus of the family Pneumoviridae.
	* HRSV is the most common cause of lower respiratory tract infections in children…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 17 Jan 2024 21:36:15 +0000</pubDate>
        </item>
        <item>
            <title>renal tubular acidosis (RTA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rta</link>
            <description>renal tubular acidosis (RTA)

see also:

	* metabolic acidosis
	* acid-base physiology
	* wikipedia

introduction

	* RTA is a group of conditions which cause a chronic metabolic acidosis due to either:
		* impaired ability to secrete hydrogen ions in the distal convoluted tubule (type I RTA) 
		* impaired ability to absorb bicarbonate in the proximal convoluted tubule (type II RTA)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 18 Jan 2010 03:38:29 +0000</pubDate>
        </item>
        <item>
            <title>rubella</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=rubella</link>
            <description>rubella

see also:

	* viruses
	* paediatric exanthems

introduction

	* once an extremely common exanthem of childhood, now quite rare in vaccinated regions
	* whilst the viral illness is generally mild, it does pose a major risk to the fetus if pregnant mothers become infected
	* the rubella virus is a member of the Rubivirus genus of the family</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 31 Oct 2018 03:34:13 +0000</pubDate>
        </item>
        <item>
            <title>sacro-iliitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sacro-iliitis</link>
            <description>sacro-iliitis

see also:

	* The adult with back pain in the ED
	* The elderly patient with back pain in the ED
	* arthritis - clinical patterns

introduction

clinical features

	* pain localisable to the sacro-iliac joints, and buttocks
	* pain may be referred down the legs
	* pain often aggravated by:
		* prolonged standing
		* stair climbing
		* bearing more weight on one leg than the other</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 12 Oct 2025 08:04:14 +0000</pubDate>
        </item>
        <item>
            <title>sadness</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sadness</link>
            <description>sadness

see also:

	* psychiatry and mental health
	* antidepressants
	* suicide
	* Geriatric depression scale
	* stress
	* happiness
	* depression

Introduction

	* sadness is an important negative emotion that serves many purposes to benefit us such as:
		* a trigger for the need for more attentive and detailed thinking style
		* better memory
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 May 2017 08:57:40 +0000</pubDate>
        </item>
        <item>
            <title>modified sad persons scale</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sad_person</link>
            <description>modified sad persons scale

see also:

	* suicide
	* depression

modified scale calculation

The score is calculated from 10 yes/no questions, with one point for each affirmative answer execept where indicated as 2 points:

	* S: Male sex
	* A: Age 15-29yrs or &gt; 58 years (2 points)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 15 Nov 2014 01:31:45 +0000</pubDate>
        </item>
        <item>
            <title>patient safety</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=safety</link>
            <description>patient safety

	* quality, adverse events, reporting and standards
	* The Australian Council on Healthcare Standards
	* Australian Patient Safety Foundation
	* National Patient Safety Foundation (United States)
	* Agency for Healthcare Research and Quality, Quality &amp; Patient Safety (United States)
	* Dr Garry Lane's response to proposed  Australian Council for Safety and Quality in Health Care National Safety and Quality Framework in 2009 (pdf)
	* &lt;http://www.abc.net.au/news/2018-02-13/canberra…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 13 Feb 2018 01:49:07 +0000</pubDate>
        </item>
        <item>
            <title>safe sex and reducing risk of sexual misadventures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=safe_sex</link>
            <description>safe sex and reducing risk of sexual misadventures

see also:

	* sexually transmitted infections (STDs/STIs)

introduction

	* sexually transmitted infections (STDs/STIs) are again on the rise with massive increases of prevalance over the past 10 years in Western cultures due to failure of safe sex practices which had been more adhered to in the 1990's when</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Nov 2024 11:54:04 +0000</pubDate>
        </item>
        <item>
            <title>subarachnoid haemorrhage (SAH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sah</link>
            <description>subarachnoid haemorrhage (SAH)

see also:

	* neurosurgery
	* headache
	* lumbar puncture (LP)
	* cerebrospinal fluid (CSF)
	* Western Health ED: role of LP in SAH patient information sheet (pdf)
	* AFTB lectures - SAH
	* American Journal of Critical Care. 2002;11: 48-56 - ECG changes in SAH 

	* Testing for Xanthochromia

introduction

	* SAH usually refers to the sudden onset, nontraumatic presence of blood within the subarachnoid space from some pathologic process, usually from rupture of a b…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 28 Oct 2024 02:16:14 +0000</pubDate>
        </item>
        <item>
            <title>salbutamol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=salbutamol</link>
            <description>salbutamol

also known as albuterol in USA.

see also pharmacology main index;  asthma;

actions

	* beta 2 adrenergic agonist with beta 1 adrenergic activity (see sympathomimetics) which results in:
		* bronchodilation hence used in Mx of asthma
		* tachycardia
		* tremors
		* hypokalaemia from increased movement of K into cells</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Jan 2012 04:05:19 +0000</pubDate>
        </item>
        <item>
            <title>Salmonella</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=salmonella</link>
            <description>Salmonella

see also:

	* clinically important bacteria
	* antibiotics
	* shigella
	* Salmonella typhi (typhoid enteric fever)
	* paratyphoid enteric fever
	* gastroenteritis

introduction

	* Salmonella are Gram negative anaerobe clinically important bacteria and along with Campylobacter are the most common bacterial causes of gastroenteritis
	* certain host factors make humans particularly susceptible to infection, contracted by ingesting contaminated food or water with as little as 200 bacter…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Jan 2012 23:32:43 +0000</pubDate>
        </item>
        <item>
            <title>sarcoidosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sarcoidosis</link>
            <description>sarcoidosis

see also:

	* the chest X-ray (CXR)
	* respiratory medicine
	* wikipedia

Introduction

	* a chronic disease in which granulomas form as nodules in multiple organs, especially lungs and LNs, but also skin (25%), eyes, liver, heart, kidneys
	* commonly improves or clears up spontaneously - most have no symptoms after 9 years but 50% have relapses and 10% develop serious disability - usually respiratory failure</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Sep 2024 00:21:47 +0000</pubDate>
        </item>
        <item>
            <title>sarcopenia / generalised muscle wasting</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sarcopenia</link>
            <description>sarcopenia / generalised muscle wasting

see also:

	* weakness of the lower limb(s) / weak in the knees
	* motor neurone disease (MND)
	* exercise for health

Introduction

	* sarcopenia is a very common problem with aging and is a leading cause of frailty
	* it is characterized by progressive and generalized loss of skeletal muscle mass and strength</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Feb 2026 22:50:10 +0000</pubDate>
        </item>
        <item>
            <title>SARS virus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sars</link>
            <description>SARS virus

see also:

	* viruses
	* influenza
	* Middle Eastern Respiratory Syndrome - Corona Virus (MERS-CoV)
	* Wuhan outbreak of SARS-like virus in Dec 2019

introduction

	* SARS is caused by a virus from the family coronavirus. 
	* 1st discovered in 2003 in southern China, SARS went on to affect more than 8,000 people in more than two dozen countries in North America, South America, Europe and Asia, before it was contained.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 20 Jan 2020 21:02:26 +0000</pubDate>
        </item>
        <item>
            <title>small bowel obstruction</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sbo</link>
            <description>small bowel obstruction

see also:

	* central / periumbilical abdominal pain in the ED
	* the patient with acute abdominal pain in the ED
	* large bowel obstruction
	* Emedicine
	* Western Health's pathway for mx of small bowel obstruction (pdf)

introduction

	* SBOs can be partial or complete, simple (ie, non-strangulated) or strangulated (40%)). 
	* strangulated obstructions are surgical emergencies. If not diagnosed and properly treated, vascular compromise leads to bowel ischemia and furth…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 20 Jan 2021 10:24:31 +0000</pubDate>
        </item>
        <item>
            <title>spontaneous bacterial peritonitis (SBP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sbp</link>
            <description>spontaneous bacterial peritonitis (SBP)

see also:

	* suspected peritonitis in peritoneal dialysis patients
	* cirrhosis
	* ascites</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 17 Aug 2013 14:30:38 +0000</pubDate>
        </item>
        <item>
            <title>scabies</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=scabies</link>
            <description>scabies

see also:

	* acute generalized non-vesicular non-purpuric rashes covering most parts of the body
	* the linear skin lesion or rash
	* dermatitis herpetiformis
	* mites
	* parasites

Introduction

	* in 1687, Cestoni: discovered the mite, ascaris, as the cause of scabies
	* scabies is a very easily spread skin condition caused by the mite burrowing under the skin and causing very pruritic, often linear lesions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 04 Apr 2020 08:35:24 +0000</pubDate>
        </item>
        <item>
            <title>scalp and hair conditions</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=scalp_hair</link>
            <description>scalp and hair conditions

see also:

	* dermatology
	* facial rashes
	* scalp folliculitis
	* alopecia

Introduction

	* being highly exposed to the environment, the scalp and hair are common sources of issues, in particular, dandruff from dry flaky skin such as by atopic eczema, seborrheic dermatitis, psoriasis (scaly, silvery, sharply defined skin patches),</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Feb 2026 10:34:35 +0000</pubDate>
        </item>
        <item>
            <title>schistosomiasis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=schistosomiasis</link>
            <description>schistosomiasis

see also:

	* parasites
	* antihelminths
	* travel medicine
	* wikipedia

introduction

	* also known as bilharzia, bilharziosis or snail fever
	* it is a parasitic disease caused by several species of trematodes (platyhelminth infection, or “flukes”), a parasitic worm of the genus Schistosoma.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Jan 2012 03:17:05 +0000</pubDate>
        </item>
        <item>
            <title>schizophrenia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=schizophrenia</link>
            <description>schizophrenia

see also:

	* psychiatry and mental health
	* anti-psychotic medications

introduction

	* The incidence and prevalence of schizophrenia show prominent variation between locations.
	* Males are more likely to develop schizophrenia than females (1.4 : 1)
	* Migrant status, urban birth or residence, and advanced paternal age are associated with an increased risk of developing schizophrenia.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Jan 2026 22:32:20 +0000</pubDate>
        </item>
        <item>
            <title>sciatica</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sciatica</link>
            <description>sciatica

see also:

	* The adult with back pain in the ED
	* mechanical musculo-skeletal lower back pain
	* high lumbar disc prolapse
	* lumbar disc prolapse
	* historical aspects of sciatica
	* Vic. Health patient information sheet - back pain (pdf)

introduction

	* acute and acute exacerbations of chronic back pain are a very common presentation to an adult ED
	* many of these have pain radiating down a leg or buttock with or without paraesthesiae or weakness and are thus given a clinical di…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 28 Dec 2024 22:25:19 +0000</pubDate>
        </item>
        <item>
            <title>historical aspects of sciatica</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sciatica_history</link>
            <description>historical aspects of sciatica

see also:

	* sciatica
	* A History of Lumbar Disc Herniation From Hippocrates to the 1990s

ancient times

	* the first descriptions of sciatica go back to ancient times and often were given supernatural explanations involving demonic forces
		*  Germans’ witch’s shot (Hexenschuß) 
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 24 Sep 2018 13:13:10 +0000</pubDate>
        </item>
        <item>
            <title>scleroderma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=scleroderma</link>
            <description>scleroderma

see also:

	* connective tissue (CT) disorders
	* ENA (extractable nuclear antigen)
	* autoimmune disease

introduction

	* scleroderma is a autoimmune connective tissue disorder characterised by “hardening” of the skin +/- internal organs
	* there is currently no curative treatment for the disease itself

limited cutaneous systemic scleroderma</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 Feb 2024 07:54:22 +0000</pubDate>
        </item>
        <item>
            <title>sclerosing cholangitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sclerosing_cholangitis</link>
            <description>sclerosing cholangitis

see also:

	* primary sclerosing cholangitis / primary biliary cirrhosis
	* ascending cholangitis

Introduction

	* scarring of the bile ducts which may be:
		* primary sclerosing cholangitis / primary biliary cirrhosis, or
		* secondary causes of sclerosing cholangitis 
			*  intraductal stone disease
			*  surgical or blunt abdominal trauma
			*  intra-arterial chemotherapy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 23 Dec 2018 10:54:07 +0000</pubDate>
        </item>
        <item>
            <title>systemic capillary leak syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=scls</link>
            <description>systemic capillary leak syndrome

see also:

Introduction

	*  a rare episodic disorder characterised but increased permeability of capillary walls and loss of plasma protein into the tissues which may be life threatening
	*  no clear definite hereditary pattern</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 13 Jun 2021 00:28:40 +0000</pubDate>
        </item>
        <item>
            <title>scombroid histamine food poisoning due to spoiled fish</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=scombroid</link>
            <description>scombroid histamine food poisoning due to spoiled fish

see also:

	* toxinology
	* food poisoning
	* ciguatera toxin reef fish food poisoning
	* illness after eating seafood

introduction

	* a form of potentially fatal dose related food poisoning due to a build up of chemical toxins due to inadequate refrigeration in certain types of fish such as:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Apr 2022 23:42:40 +0000</pubDate>
        </item>
        <item>
            <title>scrotal infusion with saline</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=scrotal_infusion</link>
            <description>scrotal infusion with saline

see also:

	* urology
	* safe sex and reducing risk of sexual misadventures

Introduction

	* also called “saline ball injection”, it seems that the practice of infusing 500-1000mL of warmed normal saline into the scrotum usually using a 18G IV cannula (usually takes about 1hr per 500mL) is increasing despite it being a highly risky behavior with potential serious consequences</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Oct 2024 05:56:22 +0000</pubDate>
        </item>
        <item>
            <title>acute scrotal pain or swelling</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=scrotal_pain</link>
            <description>acute scrotal pain or swelling

see also:

	* torsion of testes
	* groin herniae
	* epididymo-orchitis
	* renal colic
	* RCH guideline - acute scrotal pain or swelling
	* Western Health surgery pathway - the painful testicle 

introduction

	* adolescents and young adults with acute onset of testicular pain and tenderness should be regarded as a surgical emergency with possible torsion of testes as infarction of the testes increases with duration and poor prognoses if duration exceeds 4 hours.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 04 Dec 2018 07:56:14 +0000</pubDate>
        </item>
        <item>
            <title>illness after eating seafood</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=seafood</link>
            <description>illness after eating seafood

see also:

	* toxinology
	* ciguatera toxin reef fish food poisoning

Introduction

	* illnesses, usually, allergic reactions, are relatively common after eating seafood, however there are a range of other differentials that should be onsidered.

Differential diagnosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 16 Apr 2022 00:55:25 +0000</pubDate>
        </item>
        <item>
            <title>medical search engines</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=search</link>
            <description>medical search engines

see also:

	* medical web portals, directories, news aggregators, etc

searching the OzEMedicine wiki

	* find documents either via:
		* search function at top right
			* use the full word or words
			* if document page names contain the search term, these pages will be displayed preferentially</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Apr 2025 00:33:06 +0000</pubDate>
        </item>
        <item>
            <title>seborrheic dermatitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=seb_dermatitis</link>
            <description>seborrheic dermatitis

see also:

	* scalp and hair conditions
	* dermatology

Introduction

	* seborrheic dermatitis (SD) a common condition characterised by dry, flaky or greasy skin especially around scalp and areas with sebum glands
	* it is a common cause of dandruff
	* SD has a predominantly bimodal distribution, with a peak during infancy (2-12 months of age) and another peak in early adulthood.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Feb 2026 10:13:34 +0000</pubDate>
        </item>
        <item>
            <title>rapid sedation of the agitated or aggressive patient in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sedation_rapid</link>
            <description>rapid sedation of the agitated or aggressive patient in the ED

see also:

	* managing violence or the aggressive patient in the ED
	* Sedation Assessment Tool (SAT) for Mx of agitated patients in ED
	* use of mechanical restraints
	* Safer Care Victoria clinical guidance - acute behavioural disturbance Mx in the ED

introduction

	* see also managing violence or the aggressive patient in the ED for further information on the possible medical causes of aggressive behaviour

sedation of the agita…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:35:28 +0000</pubDate>
        </item>
        <item>
            <title>Sedation Assessment Tool (SAT) for Mx of agitated patients in ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sedation_sat</link>
            <description>Sedation Assessment Tool (SAT) for Mx of agitated patients in ED

see also:

	* managing violence or the aggressive patient in the ED

introduction

	* the SAT is a simplified version of the altered mental state score (AMSS) tailored for rapid and easy assessment of the degree of agitation or sedation in the agitated patient being managed in the ED using</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Jan 2012 05:37:56 +0000</pubDate>
        </item>
        <item>
            <title>sedatives, hypnotics and anxiolytics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sedatives</link>
            <description>sedatives, hypnotics and anxiolytics

see also:

	* pharmacology main index
	* anaesthetics
	* pain, analgesia and analgesics
	* insomnia
	* sleep hygiene
	* stress
	* anxiety
	* barbiturates
	* benzodiazepines
	* RCH guideline - paediatric procedural sedation guideline
	* Sedation Assessment Tool (SAT) for Mx of agitated patients in ED
	* managing violence or the aggressive patient in the ED</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Jan 2012 05:39:37 +0000</pubDate>
        </item>
        <item>
            <title>seizures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=seizures</link>
            <description>seizures

see also:

	* drug-induced seizures
	* paediatric seizures and paediatric patient information sheets
	* Vic DHS - patient information sheet - seizures (pdf)
	* febrile convulsions in children
	* Is it really epilepsy?
	* seizures due to severe acute hyponatraemia
	* anticonvulsants
	* neurology
	* eclampsia
	* AFTB Lectures - Mx of status epilepticus (2008)

Mx of status epilepticus

basic life support

	* oxygen
	* protect airway
	* exclude hypoglycaemia early!
	* iv access - consider…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 30 Jan 2026 03:47:31 +0000</pubDate>
        </item>
        <item>
            <title>is it really epilepsy?</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=seizures_dx</link>
            <description>is it really epilepsy?

see also:

	* seizures
	* drug-induced seizures
	* paediatric seizures
	* febrile convulsions in children
	* anticonvulsants
	* neurology
	* syncope / near syncope


introduction

	* An incorrect diagnosis of a seizure disorder can have many negative consequences for the patient, including expensive and potentially toxic medication regimens, loss of driving privileges, and loss of work.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 23 Apr 2014 06:04:20 +0000</pubDate>
        </item>
        <item>
            <title>febrile convulsions in children</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=seizures_febrile</link>
            <description>febrile convulsions in children

see also:

	* Mx of status epilepticus
	* seizures in children
	* fever - the febrile response to infections
	* febrile child
	* RCH clinical guidelines - Mx of febrile convulsions

patient information sheets

	* RCH - seizures - safety issues and how to help (pdf)
	* RCH - febrile convulsions (pdf)
	* RCH - intranasal midazolam (pdf)
	* RCH - buccal midazolam (pdf)

features that suggest febrile convulsion:

	* temperature &gt; 38.5 deg. C and age 6mths - 5yrs, esp…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 30 Jan 2014 00:45:35 +0000</pubDate>
        </item>
        <item>
            <title>drug-induced seizures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=seizures_od</link>
            <description>drug-induced seizures

see also seizures, toxicology, neurology, anticonvulsants

NB. AVOID phenytoin in drug-induced seizures.

mechanisms of seizures

Domoic acid (from mussels)

	* =&gt; decreased GLU reuptake =&gt; GIT effects, confusion, seizures

isoniazid

	* =&gt; inhibits pyridoxyl phosphate =&gt; impairs glutamic acid decarboxylase</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 02 Aug 2025 12:31:22 +0000</pubDate>
        </item>
        <item>
            <title>paediatric seizures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=seizures_paed</link>
            <description>paediatric seizures

see also:

	* Mx of status epilepticus
	* paediatric emergency medicine
	* febrile convulsions
	* anticonvulsants
	* RCH clinical guidelines - Mx of afebrile seizures
	* RCH clinical guidelines - Mx of febrile convulsions

patient information sheets

	* RCH patient information epilepsy
	* RCH - seizures - safety issues and how to help (pdf)
	* RCH - febrile convulsions (pdf)
	* RCH - intranasal midazolam (pdf)
	* RCH - buccal midazolam (pdf)
	* RCH - seizures after acquired …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 May 2022 07:11:54 +0000</pubDate>
        </item>
        <item>
            <title>Withdrawal of anticonvulsant Rx</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=seizures_withdrawingrx</link>
            <description>Withdrawal of anticonvulsant Rx

see also seizures, anticonvulsants

Withdrawal of anti-epileptic drugs in seizure-free adults:

Factors predicting seizure recurrence following antiepileptic drug withdrawal:

associated with increased risk:

	* juvenile myoclonic epilepsy - esp. if sleep deprivation or excess alcohol; responds well to valproate;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Sep 2008 08:37:30 +0000</pubDate>
        </item>
        <item>
            <title>selenium poisoning / selenosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=selenosis</link>
            <description>selenium poisoning / selenosis

see also:

	* foods that may be toxic or bad for you

Introduction

	* selenium is an essential trace element however, it is toxic if taken in excess at levels &gt; 400-800mcg/d and can lead to selenosis
	* Recommended Dietary Allowances (RDAs) for selenium is 55 μg/day</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Sep 2023 10:26:38 +0000</pubDate>
        </item>
        <item>
            <title>sepsis / septicaemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sepsis</link>
            <description>sepsis / septicaemia

see also:

	* meningococcal septicaemia
	* infectious diseases
	* the febrile child
	* the febrile adult
	* febrile neutropenia
	* NSW CEC Sepsis Kills program
	* NEJM 2014: ProCESS Trial
		* as long as early recognition and commencement of ED care, there was no significant advantage, with respect to mortality or morbidity, of protocol-based resuscitation over bedside care that was provided according to the treating physician’s judgment.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:35:56 +0000</pubDate>
        </item>
        <item>
            <title>septic shock</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=septic_shock</link>
            <description>septic shock

see also:

	* sepsis / septicaemia
	* the shocked hypotensive patient
	* serum lactate
		* &lt;https://emcrit.org/isepsis/isepsis-lactate-myths/&gt;

	* RCH guidelines - septic shock

References

	* 2008 International guidelines for management of severe sepsis and septic shock from the Surviving Sepsis Campaign in the USA. Hosted on NICS blog
		* survivingsepsis.org

	* “lactate clearance but not initial lactate level is significantly associated with a decreased mortality rate. Furthermo…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Jan 2018 01:15:14 +0000</pubDate>
        </item>
        <item>
            <title>Serotonin physiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=serotonin</link>
            <description>Serotonin physiology

see also: serotonin receptors and pharmacology, Serotonin syndrome, autacoids

Serotonin (5-OH tryptamine):

	* It had been known that when blood clotted, a vasoconstrictor was released in serum &amp; this was a nuisance in studies in late 1940's during searches for vasoconstrictors. In 1948, it was crystallised &amp; named serotonin &amp; soon found to be 5-HT.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Sep 2008 13:05:10 +0000</pubDate>
        </item>
        <item>
            <title>serotonin syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=serotoninsyndrome</link>
            <description>serotonin syndrome

see also:

	* neuroleptic malignant syndrome
	* SSRI/SNRI antidepressants

Introduction

	* Serotonin syndrome is due to excess activation of post-synaptic 5HT1A in lower brain stem &amp; spinal cord, perhaps with some dopaminergic involvement.
	* 5HT is derived from L-tryptophan via tryptophan hydroxylase which converts it to 5-OH tryptophan which is then decarboxylated to form 5HT (5-OH tryptamine or serotonin).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 07:44:26 +0000</pubDate>
        </item>
        <item>
            <title>serotonin receptors and pharmacology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=serotonin_ph</link>
            <description>serotonin receptors and pharmacology

see also:

	* serotonin physiology
	* serotonin syndrome

5-HT1 receptor:

	* 6 sub-types: A-F;

5-HT1A:

	* found in Raphe nuclei &amp; hippocampus, medullary neurons =&gt; decr. BP;
		* =&gt; decr. cAMP =&gt; veno/arteriolodil. without EDRF;

	* social cognitive component modulated by frontal &amp; temporal cortices in conjunction with the hippocampus &amp; mediated by 5HT1A and noradrenaline neurotransmission</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 25 Dec 2020 23:47:01 +0000</pubDate>
        </item>
        <item>
            <title>serum electrophoresis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=serum_electrophoresis</link>
            <description>serum electrophoresis

see also:

	* immunoglobulins
	* multiple myeloma
	* serum free light chains

Introduction

	* serum electrophoresis assesses the relative and total amounts of various groups of proteins within the serum and these generally group into several bands as outlined below

Indications</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 09 Jun 2022 01:04:05 +0000</pubDate>
        </item>
        <item>
            <title>serum free light chains</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=serum_freelightchains</link>
            <description>serum free light chains

see also:

	* immunoglobulins
	* multiple myeloma
	* serum electrophoresis

Introduction

	* serum free light chains assays are used in conjunction with serum electrophoresis in the investigation and monitoring of blood dyscrasias such as multiple myeloma

Interpretation of results

	* In general, significantly increased free light chain production and an abnormal kappa/lambda ratio indicate a poorer prognosis and an increased risk of disease progression.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 09 Jun 2022 01:12:36 +0000</pubDate>
        </item>
        <item>
            <title>serum sickness</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=serum_sickness</link>
            <description>serum sickness

see also:

	* allergy and hypersensitivity reactions
	* urticaria

introduction

	* serum sickness is a Gell &amp; Coombs Type III delayed onset hypersensitivity reaction 
	* it is mediated by immune complexes (IgG/IgM)
	* Ab-Ag complexes in circulation in ratio 1-2:1 may cause deposition onto cell membranes activating complement 
	* this causes local inflammation including urticaria with joint effusions</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Jan 2012 05:16:25 +0000</pubDate>
        </item>
        <item>
            <title>Sever's disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=severs</link>
            <description>Sever's disease

see also:

	* arthritis - clinical patterns
	* Vic. Better Health - patient fact sheet - Sever's disease

introduction

	* a cause of heel pain in pubertal adolescents which is exacerbated by running and jumping activities, first described by J.W. Sever in 1912 
	* most commonly affects boys aged 12 to 14 years and girls aged 10 to 12 years</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Sep 2009 07:26:41 +0000</pubDate>
        </item>
        <item>
            <title>sexual assault / rape</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sexual_assault</link>
            <description>sexual assault / rape

see also:

	* domestic violence
	* sexually transmitted infections (STDs/STIs)
	* West CASA sexual assault crisis care unit service (doc) - intranet only
	* sexual health services in Victoria:
		*  West CASA - Centre Against Sexual Assault 
		*  Melbourne Sexual Health Centre (MSHC) in Carlton 


Mx of patients presenting to a Victorian ED alleging sexual assault

	* ED staff should follow their local procedures for Mx of these patients</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 12 May 2021 06:41:01 +0000</pubDate>
        </item>
        <item>
            <title>Severe fever with thrombocytopenia syndrome virus (SFTSV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sftsv</link>
            <description>Severe fever with thrombocytopenia syndrome virus (SFTSV)

see also:

	* viruses

introduction

	* an emerging infectious zoonosis in China, Japan, and South Korea
	* newly identified tick-borne bunyavirus (of genus Phlebovirus) discovered in 2007
	* similar to viral haemorrhagic fevers</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 27 Dec 2013 05:44:13 +0000</pubDate>
        </item>
        <item>
            <title>soluble guanylate cyclase stimulators</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sgc</link>
            <description>soluble guanylate cyclase stimulators

see also:

	* heart failure with reduced ejection fraction (HFrEF)

Introduction

	* soluble guanylate cyclase stimulators are a class of therapeutic agents that increase intracellular cyclic GMP (cGMP) levels, leading to smooth muscle relaxation and improved blood flow by targeting the nitric oxide-sGC-cGMP pathway via directly stimulating the sGC enzyme independently of nitric oxide (NO) and sensitize sGC to existing NO</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Mar 2026 03:53:23 +0000</pubDate>
        </item>
        <item>
            <title>gliflozins / SGLT2 inhibitors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sglt2inhib</link>
            <description>gliflozins / SGLT2 inhibitors

see also:

	* SGLT2 inhibitor induced diabetic ketoacidosis (gliflozin DKA)
	* oral hypoglycaemic agents
	* chronic renal failure
	* diabetes mellitus

Introduction

	* SGLT2 inhibitors have revolutionized the treatment of patients with T2DM with established or at risk for atherosclerotic cardiovascular disease (ASCVD) and patients with diabetic kidney disease and well as non-diabetic patients with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 01 Oct 2023 16:42:57 +0000</pubDate>
        </item>
        <item>
            <title>Victorian State health emergency response plan (SHERP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sherp</link>
            <description>Victorian State health emergency response plan (SHERP)

see also:

	* Vic. State Health Emergency Response Plan SHERP official website
	* disaster medicine
	* Victorian medical assistance teams for disaster Mx (VMAT)
	* there are other Victorian plans or gudelines available to assist SHERP:
		*  Communicable Disease Incident and Emergency Operational Response Plan
		*  Food Incident and Emergency Operational Response Plan</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 02 Jan 2020 22:42:31 +0000</pubDate>
        </item>
        <item>
            <title>shigella</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=shigella</link>
            <description>shigella

see also:

	* gastroenteritis
	* traveller's diarrhoea

introduction

	* Shigellosis is an infectious gastroenteritis usually causing dysentery-type pattern 
	* Shigella are Gram-negative, facultative anaerobes
		* it is endemic in developing countries were sanitation is poor resulting in around half of cases of bloody diarrhoea / dysentery in young children in those areas</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 11 Jul 2023 05:32:05 +0000</pubDate>
        </item>
        <item>
            <title>the shocked hypotensive patient</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=shock</link>
            <description>the shocked hypotensive patient

see also:

	* sepsis / septicaemia
	* anaphylaxis
	* blood loss:
		* trauma
		* upper GIT bleeding
		* lower GIT bleeding
		* retroperitoneal bleeding
			* abdominal aortic aneurysm (AAA)
			* thoracic aortic aneurysm
			* ruptured splenic artery aneurysm
			* ruptured iliac artery aneurysm
			* renal bleeding eg. ruptured renal artery aneurysm</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 Nov 2023 23:14:11 +0000</pubDate>
        </item>
        <item>
            <title>short QTc</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=shortqtc</link>
            <description>short QTc

see also:

	* The basics of reading an ECG
	* patterns of ECGs
	* torsade de pointes VT
	* prolonged QTc

Introduction

	* the normal QTc on the ECG is 360-390msec in males and 370-400msec in females
	* most doctors are well aware of the potential lethal effects of prolonged QTc, but few are aware that short QTc  with QT &lt; 320ms and a QTc &lt; 340ms can also cause sudden death.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Nov 2017 01:23:24 +0000</pubDate>
        </item>
        <item>
            <title>Shoulder Dislocation (antero-inferior)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=shoulderdis_ant</link>
            <description>Shoulder Dislocation (antero-inferior)

see also:

	* &lt;http://broadcomplex.com.au/2010/05/30/the-shoulder/&gt;

Introduction:

	*  an extremely painful dislocation, and a common challenge for emergency doctors
	*  sedation-free reduction has benefits for the patient but be mindful that patient selection is key</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 17 Mar 2019 10:38:17 +0000</pubDate>
        </item>
        <item>
            <title>posterior dislocation of the shoulder</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=shoulderdis_post</link>
            <description>posterior dislocation of the shoulder

see also:

	* Phong Tran's WH orthopaedic website - posterior dislocation shoulder
	* Neil Cunningham's website on posterior dislocation of the shoulder
	* Shoulder Dislocation (antero-inferior)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 07 Feb 2019 01:09:50 +0000</pubDate>
        </item>
        <item>
            <title>the painful shoulder</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=shoulderpain</link>
            <description>the painful shoulder

see also:

	* orthopaedics in the ED
	* the acutely painful elbow
	* interscapular thoracic back pain

introduction

	* shoulder pain is a very common presentation to the ED
	* one needs to differentiate local injury or inflammation to that from referred pain

referred pain

	* a painful stimulus involving the diaphragm or the mediastinum commonly results in referred shoulder tip pain, usually on the same side this may be due to</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 11 Jul 2024 03:35:52 +0000</pubDate>
        </item>
        <item>
            <title>Mx of shoulder dystocia in labour</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=shoulder_dystocia</link>
            <description>Mx of shoulder dystocia in labour

see ED Mx of 2nd stage of labour - emergency delivery; ED Mx of 3rd stage of labour - delivery of placenta;

Shoulder dystocia:

	* 0.13-0.2% of vaginal deliveries
	* due to shoulders being in AP position rather than oblique when head delivers

risk factors:

	* fetal macrosomia (BW &gt; 4000g)
	* maternal obesity
	* materal diabetes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Apr 2013 06:45:01 +0000</pubDate>
        </item>
        <item>
            <title>Sunshine ED Fast Track</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sh_fast_track</link>
            <description>Sunshine ED Fast Track

see also:

	* Western Health ED main page
	* Western Health ED medical orientation
	* nurse initiated ED treatment

links to care guidelines relevant to fast track

	* ensure YOU check EVERY patient's ID wrist band and comply with patient identification processes
	* ensure you order investigations for the correct patient</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 05 May 2018 04:18:33 +0000</pubDate>
        </item>
        <item>
            <title>syndrome of inappropriate ADH secretion (SIADH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=siadh</link>
            <description>syndrome of inappropriate ADH secretion (SIADH)

see also:

	* hyponatraemia
	* &lt;https://www.racgp.org.au/afp/2017/september/the-suspect-siadh/&gt;

introduction

	* SIADH is increased ADH secretion despite normal or elevated plasma volume which causes reduced renal water excretion and resulting hyponatraemia and hypo-osmolality

Diagnostic criteria</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 20 Jun 2021 06:53:06 +0000</pubDate>
        </item>
        <item>
            <title>sickle cell disease (SCD)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sickle_cell</link>
            <description>sickle cell disease (SCD)

	* RCH guideline - sickle cell disease

introduction

	* sickle cell disease is a hereditary autosomal dominant haemoglobinopathy due to homozygous HbS which usually presents in childhood
	* the gene is present in 8% (2 million) of black Americans who thus have sickle cell trait but only 30,000 have homozygous HbS, thus sickle cell disease occurs in 1 in 500 African Americans</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 21 Feb 2020 23:18:01 +0000</pubDate>
        </item>
        <item>
            <title>sick sinus syndrome (SSS) / tachycardia-bradycardia syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sicksinus</link>
            <description>sick sinus syndrome (SSS) / tachycardia-bradycardia syndrome

see also:

	* bradycardia

Introduction

	* SSS is a syndrome of cardiac rhythm pathologies affecting the sinoatrial node resulting in sinoatrial node pacemaker dysfunction and/or sinoatrial conduction dysfunction</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 05 Apr 2019 03:08:06 +0000</pubDate>
        </item>
        <item>
            <title>soluble form of the interleukin-2 receptor (sIL-2R)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sil-2r</link>
            <description>soluble form of the interleukin-2 receptor (sIL-2R)

see also:

	* adaptive immunity

Introduction

	* soluble form of the receptor for interleukin-2 which can be used as a biomarker
	* also known as sCD25, sTAC, sIL2R, or IL-2RA

Physiology

	* IL-2 exerts its effects by binding to IL-2 receptors expressed by lymphocytes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 08 May 2024 10:33:16 +0000</pubDate>
        </item>
        <item>
            <title>Simulation in medical education and patient safety</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sim_ed</link>
            <description>Simulation in medical education and patient safety

See also:

	* Debrief2Learn.org simulation debriefing resource website
	* &lt;https://emsimcases.com&gt;

Introduction

	*  simulation training is a critical component of developing and maintaining the competence, confidence and efficiency required to optimise patient care and improve patient safety and as such it's goal and outcome measures should be patient safety - and not the provision of simulation itself</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Sep 2022 09:35:14 +0000</pubDate>
        </item>
        <item>
            <title>sinusitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sinusitis</link>
            <description>sinusitis

see also:

	* ears, nose and throat surgery (ENT)
	* antibiotics
	* RCH guideline - persistent nasal discharge &amp; rhinosinusitis

introduction

	* infection of the sinuses is common and often becomes chronic 
	* most commonly bilateral sinusitis is a complication of upper respiratory tract infections
	* chronic unilateral maxillary sinusitis is very suggesting of an</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2024 05:00:55 +0000</pubDate>
        </item>
        <item>
            <title>Sjögren's syndrome (SS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sjogrens_syndrome</link>
            <description>Sjögren's syndrome (SS)

see also:

	* rheumatology
	* blepharitis / dry eyes
	* autoimmune disease
	* wikipedia

introduction

	* also known as “Mikulicz disease” and “Sicca syndrome” is an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Mar 2024 14:22:40 +0000</pubDate>
        </item>
        <item>
            <title>Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sjs-ten</link>
            <description>Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN)

see also:

	* mouth ulcers
	* allergy and hypersensitivity reactions
	* erythema multiforme
	* acute rashes in adults
	* Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 11 Jul 2022 08:55:15 +0000</pubDate>
        </item>
        <item>
            <title>skin necrosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=skin_necrosis</link>
            <description>skin necrosis

see also:

	* dermatology

introduction

DDx

	* pressure necrosis leading to pressure ulcers
	* Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN)
	* peripheral vascular disease (PVD or PAD) 
	* venous gangrene
	* cholesterol embolism
	* frostbite
	* vascular compromise of skin flaps or traumatised end-artery regions
	* extravasation of vasoconstrictors such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 03 Jul 2013 04:02:22 +0000</pubDate>
        </item>
        <item>
            <title>skin nodular &quot;rash&quot;</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=skin_nodules</link>
            <description>skin nodular &quot;rash&quot;

see also:

	* dermatology
	* pustular rashes

Introduction

	* when discussing “nodular rashes” this is generally referring to “panniculitis” (inflammation of the subcutaneous tissue)
	* superficial skin nodules are a separate diagnostic entity

Panniculitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 29 Nov 2023 05:09:06 +0000</pubDate>
        </item>
        <item>
            <title>systemic lupus erythematosus (SLE)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sle</link>
            <description>systemic lupus erythematosus (SLE)

see also:

	* rheumatology
	* autoimmune disease
	* anti-nuclear antibodies (ANA)
	* Sjögren's syndrome (SS)
	* wikipedia

introduction

	* a chronic autoimmune connective tissue disease that can affect any part of the body, but most often the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system, and is thus one of the great imitators of diseases.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 14 Nov 2025 11:01:20 +0000</pubDate>
        </item>
        <item>
            <title>sleep hygiene</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sleep_hygiene</link>
            <description>sleep hygiene

see also:

	* physiology of sleep
	* insomnia
	* fatigue
	* stress
	* Coping with shift work
	* managing jet lag and your body clock

	* sleep disorders, excessive daytime sleepiness and dangers of driving with its legal ramifications:
		* Australian Roads
		* Australasian Sleep Association

	* perhaps your body clock is set early in life and inherited from your mother as with zebra fish
	* daylight savings and sleep disruption
	* caffeine and guarana helps drivers stay alert and …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 03 Feb 2026 00:02:30 +0000</pubDate>
        </item>
        <item>
            <title>physiology of sleep</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sleep_physiology</link>
            <description>physiology of sleep

see also:

	* sleep hygiene
	* insomnia
	* fatigue
	* shift work
	* Managing jet lag and your body clock

introduction

	* During a single 24 hour day we have a period of 6-10 hours when we are very sleepy. This is the time when we normally sleep. During the remaining 14-18 hours we are usually awake; however, only a portion of that waking time is suitable for intellectual effort. This period of maximum alertness may last as little as 2-6 hours. We should plan our day in suc…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 Jan 2026 22:13:15 +0000</pubDate>
        </item>
        <item>
            <title>snakebite and envenomation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=snakebite</link>
            <description>snakebite and envenomation

see also:

	* toxicology
	* Australian tiger and brown snake bites
		* Mx of Australian snake bites with evidence of envenomation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 20 Jan 2016 06:52:26 +0000</pubDate>
        </item>
        <item>
            <title>Australian snake bites</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=snakebites_australia</link>
            <description>Australian snake bites

see also:

	* Australian tiger and brown snake bites
	* Mx of Australian snake bites with evidence of envenomation
	* toxinology

	* less than 10% of snake bites result in clinically significant envenomation
	* antivenom is NOT indicated if there is no evidence of envenomation
	* a positive venom detection kit result does NOT imply envenomation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 Oct 2025 23:59:38 +0000</pubDate>
        </item>
        <item>
            <title>Mx of Australian snake bites with evidence of envenomation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=snakebites_envenomation_mx</link>
            <description>Mx of Australian snake bites with evidence of envenomation

see also:

	* first aid and Mx of suspected Australian brown and tiger snake bites
	* Australian snake bites
	* RCH guideline - snake bites and envenomation in children in Victoria
	* Vic. DOH snakebite Mx tools (2019):
		* &lt;https://bettersafercare.vic.gov.au/resources/clinical-guidance/emergency-care/management-of-snake-bite&gt;
		* flowchart for ED's
		* a clinical pathway for the management of snake bite envenomation

	* Australian Veno…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 29 Sep 2025 05:49:44 +0000</pubDate>
        </item>
        <item>
            <title>Australian tiger and brown snake bites</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=snakebites_tiger_brown</link>
            <description>Australian tiger and brown snake bites

see also:

	* Australian snake bites
	* toxinology
	* RCH guideline - snake bites and envenomation
	* Vic. DOH snakebite Mx tools (2019):
		* &lt;https://bettersafercare.vic.gov.au/resources/clinical-guidance/emergency-care/management-of-snake-bite&gt;
		* flowchart for ED's
		* a clinical pathway for the management of snake bite envenomation  

	* MJA 2013: Mx of Australian snakebites
	* Australian Venom Research Unit (AVRU): Mx of snake bites
	* NSW govt - Mx …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 29 Sep 2025 05:46:04 +0000</pubDate>
        </item>
        <item>
            <title>snoring</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=snoring</link>
            <description>snoring

see also:

	* stridor
	* wheeze
	* stertor
	* obstructive sleep apnoea (OSA)
	* physiology of sleep

Introduction

	* noise during breathing can be of various types depending upon whether awake or asleep and on where the airway obstruction arises
	* snoring is a form of stertor which occurs during sleep either as a result of vibrations of nasopharyngeal structures with raised pharyngeal collapsibility or from nasal obstruction</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 Sep 2022 22:20:13 +0000</pubDate>
        </item>
        <item>
            <title>social issues</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=social</link>
            <description>social issues

see also:

	* welcome to the OzEMedicine Wiki
	* homelessness / no fixed abode
	* poverty
	* domestic violence
	* addiction medicine (alcohol and other substance use)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 09 Feb 2025 23:29:35 +0000</pubDate>
        </item>
        <item>
            <title>sodium physiology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sodium</link>
            <description>sodium physiology

see also:

	* salt / sodium in food products
	* sodium bicarbonate
	* hyponatraemia
	* hypernatraemia
	* potassium physiology

total body sodium:

	* molar mass sodium = 23g/mol
	* total body sodium = 58 meq/kg (healthy adults);
	* non-exchangeable - 17 meqkg (25.5%)
		* bound in bone as hydroxyapatite crystal;

	* exchangeable = 41 meq/kg (70%) (85meq/kg in fetus!!)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 09 Aug 2024 01:06:36 +0000</pubDate>
        </item>
        <item>
            <title>salt / sodium in food products</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sodium_diet</link>
            <description>salt / sodium in food products

see also:

	* diets and healthy foods
	* healthy living and diets
	* hypertension

Introduction

	* excessive sodium in the diet is generally considered a very bad think, especially for people at risk of hypertension or cardiac failure
		*  of course, too rapid ingestion of salt water exceeding rate sodium can be excreted may be lethal by causing acute</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 14 Aug 2024 12:44:27 +0000</pubDate>
        </item>
        <item>
            <title>software indemnity and the law</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=software_indemnity</link>
            <description>software indemnity and the law

see also:

	* medical indemnity
	* Gatt vs Norlund dental software case Australia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 26 Nov 2015 23:23:07 +0000</pubDate>
        </item>
        <item>
            <title>soft tissue trauma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=soft_tissue_trauma</link>
            <description>soft tissue trauma

see also:

	* trauma
	* burns
	* open wounds to neck

Introduction

	* soft tissue trauma may be:
		*  blunt trauma:
			*  abrasion
			*  friction burn
			*  haematoma
			*  laceration
				*  skin is pulled apart, usually leaving underlying blood vessels and nerves intact</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Jan 2026 21:30:00 +0000</pubDate>
        </item>
        <item>
            <title>somatostatin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=somatostatin</link>
            <description>somatostatin

see also:

	* growth hormone / somatotropin
	* hormones

introduction

	* a peptide hormone produced by the hypothalamus, and from delta cells of pancreas
	* circulating half life is 2-3 minutes
	* in the brain, it passes along neuron axons to the pituitary where it:
		* inhibits secretion of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 11 May 2014 12:30:22 +0000</pubDate>
        </item>
        <item>
            <title>growth hormone / somatotropin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=somatotropin</link>
            <description>growth hormone / somatotropin

see also:

	* hormones

introduction

	* a single chain polypeptide hormone secreted by somatotropic cells within the lateral wings of the anterior pituitary gland
	* secretion is modulated by a wide variety of mechanisms including inhibition by</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 18 Nov 2025 22:08:17 +0000</pubDate>
        </item>
        <item>
            <title>sore throats in adults</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sore_throat_adult</link>
            <description>sore throats in adults

see also:

	* acute dental pain / dental abscess
	* mouth ulcers

Introduction

	* sore throats are extremely common and are usually caused by viral infections but may be bacterial tonsillitis or may be referred pain from the chest

Aetiology

pharyngitis/tonsillitis

	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2024 06:04:04 +0000</pubDate>
        </item>
        <item>
            <title>The child with a sore throat</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sore_throat_paed</link>
            <description>The child with a sore throat

see paediatric emergency medicine, antibiotics, herpes simplex virus

	* RCH guideline - sore throat
	* RCH guideline - HSV gingivostomatitis
	* NSW NETS - sore throat (pdf)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 26 Sep 2008 22:43:38 +0000</pubDate>
        </item>
        <item>
            <title>sotalol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sotalol</link>
            <description>sotalol

see also beta blockers

Summary:

	* A non-cardioselective beta-adrenergic antagonist devoid of intrinsic sympathomimetic &amp; membrane-stabilizing actions. But unlike other b-blockers, it prolongs action potential duration recorded in cardiac tissue, increases the refractory period &amp; lengthens QT interval.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 24 Feb 2009 10:06:42 +0000</pubDate>
        </item>
        <item>
            <title>speech</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=speech</link>
            <description>speech

see also:

	* the brain

Introduction

	* language is a critical component for communication, and for many how they internally process cognitive thoughts (“inner speech”)
	* speech can thus be considered in various components:
		*  unspoken “inner speech</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Aug 2025 03:17:47 +0000</pubDate>
        </item>
        <item>
            <title>spider bites in Australia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=spider_bites</link>
            <description>spider bites in Australia

see also:

	* toxinology
	* redback spider bites
	* funnel web spider bites (atraxis)
		* &lt;http://www.news.com.au/lifestyle/health/health-problems/i-felt-something-crawl-up-my-leg-this-woman-survived-every-aussies-worst-nightmare/news-story/d2a0358c13574494610ceeb1debaf04d&gt;


introduction

	* there are 2 main venomous spiders in Australia whose bite can kill humans (although no deaths since 1979 when antivenom was made available in 1980):
		* male Sydney funnel web spi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Jan 2017 22:38:31 +0000</pubDate>
        </item>
        <item>
            <title>spinal cord ischaemia / spinal TIA</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=spinalcordischaemia</link>
            <description>spinal cord ischaemia / spinal TIA

see also:

	* neurology
	* sensory &amp; motor testing including dermatomes, myotomes, reflexes, coordination &amp; balance
	* Spinal cord syndromes and lesions
	* acute spinal cord compression
	* weakness of the lower limb(s) / weak in the knees
	* acute thoracic back pain in the adult

Introduction

	* ischaemia of the spinal cord is an uncommon presentation and may be transient (“spinal TIA”) or may be more prolonged or permanent (“spinal cord infarct”</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Sep 2024 06:26:51 +0000</pubDate>
        </item>
        <item>
            <title>spinal stenosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=spinal_stenosis</link>
            <description>spinal stenosis

see also:

	* neurology
	* neurosurgery
	* oncology
	* acute spinal cord compression
	* cauda equina syndrome (CES)
	* spinal cord syndromes and lesions
	* sensory &amp; motor testing including dermatomes, myotomes, reflexes, coordination &amp; balance

Introduction

	* spinal stenosis is narrowing of the spinal canal or neural foraminae resulting in pressure on the spinal cord or nerve roots
	* lumbar stenosis is most common followed by cervical stenosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 17 Mar 2022 10:37:48 +0000</pubDate>
        </item>
        <item>
            <title>cervical spine injury</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=spine_injury_cx</link>
            <description>cervical spine injury

see also:

	* CT spine - cervical (Cx), thoracic (Tx) or lumbar (Lx)
	* trauma
	* head injury in the adult patient
	* paediatric head injury
	* Spinal cord syndromes and lesions
	* orthopaedics in the ED
	* RCH guideline - paediatric cervical spine injury
	* Western health cervical spine injury guideline (pdf) - WH intranet only
	* NHMRC Clinical guidelines for Mx of whiplash associated disorders (2008 1.4Mb pdf)
	* 2013: the tide may be turning against cervical collars
	*…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 02 May 2021 01:51:12 +0000</pubDate>
        </item>
        <item>
            <title>lumbar spine trauma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=spine_injury_lx</link>
            <description>lumbar spine trauma

see also:

	* CT spine - cervical (Cx), thoracic (Tx) or lumbar (Lx)
	* cervical spine injury
	* thoracic spine trauma
	* the lumbosacral spine Xray
	* trauma

introduction

	* initial Mx should be as per trauma
		* as per trauma protocols, spinal precautions should be utilised until cleared of potentially unstable injuries and patients should be investigated to exclude blunt renal, liver or spleen trauma, as well as fractured ribs and potential for associated pneumothorax o…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Jan 2019 23:10:49 +0000</pubDate>
        </item>
        <item>
            <title>thoracic spine trauma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=spine_injury_tx</link>
            <description>thoracic spine trauma

see also:

	* CT spine - cervical (Cx), thoracic (Tx) or lumbar (Lx)
	* thoracic spine Xray
	* cervical spine injury
	* lumbar spine trauma
	* trauma
	* kyphosis
	* scoliosis
	* Scheuermanns_disease

introduction

	* initial Mx should be as per trauma
		* as per trauma protocols, spinal precautions should be utilised until cleared of potentially unstable injuries and patients should be investigated to exclude blunt renal, liver or spleen trauma, as well as fractured ribs a…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Jan 2019 23:07:35 +0000</pubDate>
        </item>
        <item>
            <title>spirometry lung function tests</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=spirometry</link>
            <description>spirometry lung function tests

see also:

	* respiratory medicine
	* Aust. asthma Foundation QRG to spirometry for GPs
	* Aust. Asthma Foundation's buying guide for spirometers for GPs
		*  eg. amongst the least expensive are the very light, compact PC-based spirometers such as:
			*  MIR MiniSpir 2 at $AU999 excl. gst but includes 60 free turbine mouthpieces



Introduction

	* spirometry provides an assessment of lung function by measuring:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 12 Sep 2021 02:48:02 +0000</pubDate>
        </item>
        <item>
            <title>splanchnic vein thrombosis (SVT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=splanchnicvthrombosis</link>
            <description>splanchnic vein thrombosis (SVT)

see also:

	* thrombosis with thrombocytopenia syndrome (TTS / VITT / VIPIT)

Introduction

	* an uncommon site for venous thrombosis
	* two thirds of SVT patients are men

Risk factors

	* transient risk factors
		*  thrombosis with thrombocytopenia syndrome (TTS / VITT / VIPIT) eg. post-AZ Covid-19 vaccination
		*  intra-abdominal infections</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 09 Jan 2023 07:40:23 +0000</pubDate>
        </item>
        <item>
            <title>the patient who has had a splenectomy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=splenectomy</link>
            <description>the patient who has had a splenectomy

see also:

	* pneumococcus

introduction

	* patients who have had a splenectomy are at high risk of sepsis / septicaemia, in particular, due to pneumococcus
	* in addition, risk applies to those patients with “functional asplenia” such as those with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Jan 2014 05:58:37 +0000</pubDate>
        </item>
        <item>
            <title>splenic artery aneurysm</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=splenica_aneurysm</link>
            <description>splenic artery aneurysm

see also:

	* renal artery aneurysm
	* Left upper quadrant abdominal pain in the ED
	* the patient with acute RUQ pain in ED

Introduction

	*  rare cause of abdominal pain and may be the result of arterial or venous occlusion
		*  often is the presenting complaint of an underlying condition
		*  usually in a person with an underlying hematologic disorder (eg.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 06 Aug 2022 02:51:39 +0000</pubDate>
        </item>
        <item>
            <title>splenomegaly</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=splenomegaly</link>
            <description>splenomegaly

see also:

	* hepatomegaly
	* hepatosplenomegaly
	* lymphadenopathy

introduction

	* craniocaudal measurement of 11-13 cm is frequently used as the upper limit of normal splenic size on imaging studies
	* 2-5% of the population have a palpable spleen
	* patients with splenomegaly should be advised to avoid all contact sports as there is a risk of fatal splenic rupture</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 22 Feb 2022 10:12:29 +0000</pubDate>
        </item>
        <item>
            <title>spondyloarthopathies</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=spondyloarthopathies</link>
            <description>spondyloarthopathies

see also:

	* arthritis - clinical patterns
	* ankylosing spondylitis (AS)
	* sacroiliitis
	* acute thoracic back pain in the adult

introduction

	* spondyloarthopathies in its broadest sense refers to joint disease of the vertebral column which could include rheumatoid arthritis and osteoarthritis
	* it's use is usually restricted to seronegative spondyloarthropathy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Jul 2018 13:37:44 +0000</pubDate>
        </item>
        <item>
            <title>spondylolisthesis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=spondylolisthesis</link>
            <description>spondylolisthesis

see also:

	* back pain in the ED
	* orthopaedics in the ED
	* the lumbosacral spine Xray

introduction

	* a common incidental finding on the L/S spine Xray in the ED which is usually long standing but may be the result of acute trauma  and may be the cause of the back pain and nerve compression.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 11 Nov 2021 05:07:10 +0000</pubDate>
        </item>
        <item>
            <title>sports injuries</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sports_injuries</link>
            <description>sports injuries

running

	* up to 70 per cent of recreational and competitive runners sustain overuse injuries during any 12-month period.
	* 40-50% in competitive runners, 17-18% in sprinters will develop Achilles' tendonitis with risk of rupture
	* runners who strike the forefoot put 20% more forces through the ankle and Achilles' tendon with increased risk of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 23 Oct 2013 13:10:21 +0000</pubDate>
        </item>
        <item>
            <title>SSRI/SNRI antidepressants</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ssris</link>
            <description>SSRI/SNRI antidepressants

see also:

	* antidepressants
	* Serotonin physiology

introduction

	* selective serotonin reuptake inhibitors are primarily used for Rx of depression and are the 1st line agents for drug Rx of anxiety disorders, panic attacks, hyperventilation including OCD.
	* they are also used in Rx of premature ejaculation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 06 Dec 2024 21:52:02 +0000</pubDate>
        </item>
        <item>
            <title>staphylococcus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=staphylococcus</link>
            <description>staphylococcus

see also:

	* clinically important bacteria
	* antibiotics for Rx of Staph. aureus
	* innate immunity

Staphylococci:

	* Gram +ve, spherical, often in clusters, non-motile, non-sporing;
	* Catalase +ve; fermentative (cf. micrococcus oxidative);
	* Some have capsules; aerobic &amp; facultative anaerobes;
	* Grow easily on most media, best at 37°C;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 18 Dec 2025 22:43:04 +0000</pubDate>
        </item>
        <item>
            <title>welcome to the OzEMedicine Wiki</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=start</link>
            <description>welcome to the OzEMedicine Wiki

	* OzEMedicine ©2007 wiki is the world's 1st wikipedia dedicated to Emergency Medicine
	* content is created ONLY by Australian Emergency Physicians 
	* there are NO advertisements or endorsements and this extensive wikipedia is provided freely as part of</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 10 Feb 2025 02:41:40 +0000</pubDate>
        </item>
        <item>
            <title>statins</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=statins</link>
            <description>statins

see also:

	* hyperlipidaemia

introduction

	* HMGCoA reductase inhibitors, 'statins', are the first line drugs to use for most patients with hyperlipidaemia or mod-high risk of atherosclerotic cardiovascular disease. 
	* they are extremely efficacious and more than 90% of patients can tolerate them with negligible or no adverse effects.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 26 Mar 2024 09:34:41 +0000</pubDate>
        </item>
        <item>
            <title>sexually transmitted infections (STDs/STIs)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=std</link>
            <description>sexually transmitted infections (STDs/STIs)

see also:

	* safe sex and reducing risk of sexual misadventures
	* clinically important bacteria
		* chlamydia
		* gonococcus
		* syphilis
		* LGV
		* chancroid
		* mycoplasma genitalium

	* viruses
		* Herpes simplex virus (HSV)
		* human papilloma virus (HPV)
		* HIV / AIDS

	* parasitic
		* pubic lice

	* antibiotics
	* gynaecology
	* pelvic inflammatory disease (PID)
	* epididymo-orchitis
	* epidemiology data:
		*  Australian National Notifiable …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 Jan 2025 22:29:35 +0000</pubDate>
        </item>
        <item>
            <title>steatohepatitis (fatty liver)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=steatohepatitis</link>
            <description>steatohepatitis (fatty liver)

see also:

	* hepatitis
	* liver diseases

introduction

	* steatohepatitis is a progression of fatty liver disease and may progress on to cirrhosis and hepatocellular carcinoma
	* initially it is asymptomatic and may only be discovered as a result of:
		* raised liver function tests (LFTs)
		* hepatomegaly
		* diagnosis on USS or CT abdo</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 18 Dec 2025 21:53:47 +0000</pubDate>
        </item>
        <item>
            <title>stem cell therapy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=stemcellrx</link>
            <description>stem cell therapy

introduction

	* stem cell Rx is the use of pluripotent stem cells to repair or replace damaged tissues
	* in 1998, the 1st human stem cells to be used were harvested from human embryos and called embryonic stem cells (ESCs) however this raised ethical issues</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 30 Jan 2014 01:43:12 +0000</pubDate>
        </item>
        <item>
            <title>sterile pyuria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sterile_pyuria</link>
            <description>sterile pyuria

see also:

	* urinalysis
	* urinary tract infections (UTIs) / cystitis

introduction

	* sterile pyuria is the finding of &gt; 10 white cells per microlitre of uncentrifuged urine of leukocytes in clean urine samples without bacterial growth on culture

aetiology

	* partially treated urinary tract infections (UTIs) / cystitis
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 02 Jan 2014 07:30:58 +0000</pubDate>
        </item>
        <item>
            <title>sterilisation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sterilisation</link>
            <description>sterilisation

see also:

	* aseptic non-touch technique (ANTT)
	* clinically important bacteria

UV sterilisation

	* UV-C light with wavelengths of 254nm are typically used to rapidly sterilise air, water or surfaces
		*  in high humidity environments such as cool rooms, “vacuum UV” 185nm lamps capable of also creating ozone which can oxidize odour-producing chemicals and provide some germicidal activity may also be an option</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 06 Jul 2020 10:59:17 +0000</pubDate>
        </item>
        <item>
            <title>stertor</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=stertor</link>
            <description>stertor

see also:

	* stridor
	* wheeze
	* noisy breathing
	* snoring
	* obstructive sleep apnoea (OSA)
	* Stridor vs Wheeze vs Stertor and snoring in children (pdf)

Introduction

	* noise during breathing can be of various types depending upon whether awake or asleep and on where the airway obstruction arises
	* stertor is primarily an inspiratory noise arising from the upper airways and in the unconscious patient, it generally indicates upper airway obstruction and potentially impending deat…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Feb 2019 21:54:50 +0000</pubDate>
        </item>
        <item>
            <title>stillbirth / FDIU</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=stillbirth</link>
            <description>stillbirth / FDIU

see also:

	* pregnancy
	* Obstetrics
	* decreased fetal movements (DFM or RFM)
	* fetal growth restriction (FGR / SGA / IUGR)
	* WH guideline for stillbirths and neonatal deaths - intranet only

Introduction

	* a fetal death in utero (FDIU) is defined as:
		*  “The death of a baby in utero after 20 completed weeks of gestation or birth weight more than 400grams if the period of gestation cannot be reliably established.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 Aug 2019 06:43:19 +0000</pubDate>
        </item>
        <item>
            <title>non-fatal suffocation or strangulation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=strangulation</link>
            <description>non-fatal suffocation or strangulation

see also:

	* domestic violence
	* trauma
	* &lt;https://www.familyjusticecenter.org/wp-content/uploads/2019/04/Recommendations-for-Medical-Radiological-Eval-of-Non-Fatal-Strangulation-v4.9.19.pdf&gt;
	* 60min Vimeo video training webinar: Insight Exchange Module Strangulation (includes Auslan) 
	* NSW Govt resource: Managing non-fatal strangulation in the emergency department 
	* online resources for victims:
		*  Queensland Centre for Domestic and Family Viole…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 20 Jun 2023 00:43:33 +0000</pubDate>
        </item>
        <item>
            <title>streptococcus / streptococcal infections</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=streptococcus</link>
            <description>streptococcus / streptococcal infections

see also:

	* clinically important bacteria
	* VicHealth patient information sheet Group A Strept infections

Introduction

	* Streptococcal bacteria are Gram +ve cocci belonging to the phylum Firmicutes and the order Lactobacillales (lactic acid bacteria) and are a common cause of infection
	* they grown in pairs or in chains hence the name of the genus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 22 Aug 2023 13:15:01 +0000</pubDate>
        </item>
        <item>
            <title>urinary stress incontinence</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=stress_incontinence</link>
            <description>urinary stress incontinence

see also:

	* urinary urgency and urge incontinence
	* urinary incontinence
	* &lt;https://www.racgp.org.au/afp/2017/september/adult-male-stress-and-urge-urinary-incontinence/&gt;

Introduction

	* involuntary loss of control of urine is a common problem and if it is recurrent becomes a major impact on a person's life and socialisation
	* urinary continence requires:
		*  a functional autonomic bladder sphincter</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Jul 2019 10:25:08 +0000</pubDate>
        </item>
        <item>
            <title>stridor</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=stridor</link>
            <description>stridor

see also:

	* wheeze
	* noisy breathing
	* stertor
	* acute cough in the adult
	* The child with a cough

Introduction

	* stridor is a clinical sign of upper airway obstruction, and if it is acute, should be regarded as a life threatening emergency
	* when the site of the obstruction is outside the thoracic cage, the obstruction typically becomes worse during inspiration as negative intra-tracheal airway pressures in inspiration further narrow the airway and thus an inspiratory stridor…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Feb 2019 21:57:49 +0000</pubDate>
        </item>
        <item>
            <title>stroke (CVA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=stroke</link>
            <description>stroke (CVA)

see also:

	* ED Mx of stroke 
	* stroke patterns
	* thrombolysis in stroke
	* neurology
	* transient ischaemic attack (TIA)
	* atherosclerosis and primary prevention
	* intraventricular haemorrhage (IVH) in adults
	* NICS care bundle of documents to assist in the ED management of TIA and stroke
	* Vic. DHS - stroke care strategy recommendations (pdf)
	* Vic. DHS - stroke care strategy for Victoria (pdf)
	* Vic. DHS - clinical networks documents
	* National Stroke Foundation
	* Str…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 09 Mar 2026 06:29:35 +0000</pubDate>
        </item>
        <item>
            <title>antithrombotic Rx for prevention of stroke</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=stroke_antithromboticrx</link>
            <description>antithrombotic Rx for prevention of stroke

see also:

	* stroke (CVA)
	* atrial fibrillation
	* general anticoagulation guidelines
	* calculators:
		* CHADS2 score for determining stroke risk in patients with non-valvular AF
		* CHA2DS2-VASc score for determining stroke risk in patients with non-valvular AF
		* HAS-BLED bleeding risk scoring tool for anticoagulation Rx
		* ABCD2 Score for TIA

	* NICS care bundle of documents to assist in the ED management of TIA and stroke

introduction

	* ri…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 04 Apr 2014 06:11:56 +0000</pubDate>
        </item>
        <item>
            <title>ED Mx of stroke</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=stroke_mx</link>
            <description>ED Mx of stroke

see also stroke (CVA), neurology, transient ischaemic attack (TIA)

	* AFTB lectures - stroke (2008)
	* ED physicians can screen for dysphagia in stroke patients with 96% sensitivity
	* NICS care bundle of documents to assist in the ED management of TIA and stroke
	* 2026 AHA consensus guidelines on Mx of ischaemic stroke

patient information sheets

	* Stroke Foundation Australia - stroke information in various languages - English, Arabic, Italian, Greek, Chinese and Vietnamese…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 22 Feb 2026 23:03:23 +0000</pubDate>
        </item>
        <item>
            <title>stroke patterns</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=stroke_patterns</link>
            <description>stroke patterns

see also:

	* neurology
	* stroke (CVA)
	* weakness_UL
	* weakness of the lower limb(s) / weak in the knees
	* paraesthesiae or numbness

pure motor hemiplegia

	* lesion in the pons, posterior limb of internal capsule, or cerebral peduncle
	* paralysis of face, arm, and leg without sensory loss
	* no parietal lobe findings

pure sensory hemiparaesthesia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 11 Oct 2022 09:22:17 +0000</pubDate>
        </item>
        <item>
            <title>strongyloidiasis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=strongyloidiasis</link>
            <description>strongyloidiasis

see also:

	* parasites
	* antihelminths
	* the febrile returned traveller

introduction

	* a human parasitic disease caused by the nematode (roundworm) Strongyloides stercoralis, or sometimes S. fülleborni. 
	* thought to affect 30–100 million people worldwide, mainly in tropical and subtropical countries.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Apr 2024 12:42:50 +0000</pubDate>
        </item>
        <item>
            <title>subclavian steal syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=subclavian_steal</link>
            <description>subclavian steal syndrome

see also:

	* thoracic outlet syndrome

Introduction

	* subclavian steal syndrome is an uncommon condition characterised reduced arterial supply to the opposite arm or carotids/vertebrals when the affected arm is exercised
	* this occurs when the subclavian artery is impinged or occluded and supply to the arm is retrograde down the ipsilateral vertebral artery which</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 01 Jan 2019 08:11:28 +0000</pubDate>
        </item>
        <item>
            <title>sugammadex</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sugammadex</link>
            <description>sugammadex

see also:

	* rocuronium
	* neuro-muscular blockers

introduction

	* sugammadex is a modified gamma cyclodextrin designed to selectively reverse the effects of the neuromuscular blockers rocuronium and vecuronium
	* marketed as Bridion (Schering Plough) in vials containing 100 mg/mL solution for injection</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 13 Mar 2015 05:12:05 +0000</pubDate>
        </item>
        <item>
            <title>suicide</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=suicide</link>
            <description>suicide

see also:

	* depression
	* psychiatry and mental health
	* modified sad persons scale
	* Victorian resources:
		*  HOPE = Hospital Outreach Post-suicidal Engagement
			*  “The aim of the HOPE initiative is to provide an assertive outreach approach to people who would not usually receive follow up by a clinical mental health service. It is a different cohort of consumer with a greater emphasis on non-clinical,  psycho social support in the approach. HOPE aims to address a service gap an…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 May 2019 03:40:44 +0000</pubDate>
        </item>
        <item>
            <title>sulphonamides</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sulphonamides</link>
            <description>sulphonamides

see also:

	* antibiotics
	* co-trimoxazole

introduction

	* sulfonamides are a group of bacteriostatic antibiotics originally called sulpha or sulfa tablets
	* they were the first antimicrobial drugs, and paved the way for the antibiotic revolution in medicine.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 01:28:57 +0000</pubDate>
        </item>
        <item>
            <title>sulphonylurea oral hypoglycaemics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sulphonylureas</link>
            <description>sulphonylurea oral hypoglycaemics

see also:

	* oral hypoglycaemic agents

introduction

	* derived from the sulphonamides
	* act by increasing insulin secretion from pancreatic beta cells by binding an ATPase K+ channel =&gt; reduced K efflux =&gt; depolarisation =&gt; opens voltage gated Ca gates</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 01:08:23 +0000</pubDate>
        </item>
        <item>
            <title>suprapubic catheterisation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=suprapubic_catheterisation</link>
            <description>suprapubic catheterisation

see also:

	* urology
	* Emedicine.com
	* tips to manage complications of suprapubic catheters</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 23 May 2021 02:44:26 +0000</pubDate>
        </item>
        <item>
            <title>surgery</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=surgery</link>
            <description>surgery

see also:

	* general surgery
	* neurosurgery
	* orthopaedics
	* plastic surgery
	* ears, nose and throat surgery (ENT)
	* ophthalmology
	* thoracic surgery
	* vascular surgery</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 16 Aug 2019 07:52:51 +0000</pubDate>
        </item>
        <item>
            <title>surgical airway</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=surgical_airway</link>
            <description>surgical airway

see cricothyroidotomy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 22 Jan 2019 07:21:02 +0000</pubDate>
        </item>
        <item>
            <title>searching patients, suspicious behaviour, unknown substance, weapons or crime within the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=suspicious_behaviour</link>
            <description>searching patients, suspicious behaviour, unknown substance, weapons or crime within the ED

see also:

	* medico-legal issues in the ED
	* managing violence or the aggressive patient in the ED
	* &lt;https://www2.health.vic.gov.au/about/key-staff/chief-psychiatrist/chief-psychiatrist-guidelines/criteria-or-searches-maintain-safety-in-inpatient-unit-for-patients-visitors-staff&gt;
	* 2018 ABC news: failure to search MH patients allegedly contributes to two deaths in a NSW hospital
	* WH procedure on p…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 02 Jun 2025 14:13:36 +0000</pubDate>
        </item>
        <item>
            <title>suxamethonium</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=suxamethonium</link>
            <description>suxamethonium

see also:

	* neuro-muscular blockers
	* rapid sequence induction (RSI) for emergency intubation

patient information sheets

	* Vic. Better Health - suxamethonium information (pdf)

	* suxamethonium may cause fatal hyperkalaemia or malignant hyperthermia and is thus contraindicated if either:
		* rhabdomyolysis
		* significant hyperkalaemia with ECG changes
		* conditions which result in up-regulation of Ach receptors and increases risk of hyperkalaemia when given suxamethonium:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 24 Apr 2015 06:57:04 +0000</pubDate>
        </item>
        <item>
            <title>superior vena cava (SVC) obstruction</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=svcobstruction</link>
            <description>superior vena cava (SVC) obstruction

see also:

	* stridor

Introduction

	* the SVC is the main venous drainage of head, neck and upper limbs
	* the azygous vein drains posterior thorax and joins the SVC at level of right main bronchus 
	* obstruction of the SVC is a medical emergency, and around 60% of cases are due to underlying intrathoracic neoplasm</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 22 Jun 2020 13:18:20 +0000</pubDate>
        </item>
        <item>
            <title>the patient with swollen leg(s)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=swollen_leg</link>
            <description>the patient with swollen leg(s)

see also:

	* deep venous thrombosis (DVT)
	* congestive cardiac failure
	* nephrotic syndrome
	* pre-eclampsia and eclampsia
	* venous insufficiency of the leg

introduction

	* the patient with swollen leg or legs, or peripheral oedema is a common presentation to the ED
	* it is usual to assess whether the swelling is bilateral or not and if there is pitting oedema</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 22 Mar 2023 22:33:58 +0000</pubDate>
        </item>
        <item>
            <title>sympathomimetics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=sympathomimetics</link>
            <description>sympathomimetics

see also:

	* pharmacology main index
	* parasympathetics
	* inotropes
	* sympNS
	* parasympNS

chemical properties of sympathomimetics

	* Sympathomimetics are drugs that mimic the actions of the naturally occurring catecholamines with beta-phenylethylamine being the parent compound:

(benzene ring-CH2-CH2-NH2).</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 01 Jun 2019 04:58:39 +0000</pubDate>
        </item>
        <item>
            <title>syncope / near syncope</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=syncope</link>
            <description>syncope / near syncope

see also:

	* seizures
	* the blood donor who collapses
	* vertigo - peripheral vs central

Introduction

	* syncope and near syncope are one of the most common presentations to the ED and need to be differentiated from a primary seizure event (seizure activity may be secondary to the syncopal event if there is prolonged reduced blood supply to the brain)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Mar 2026 23:22:10 +0000</pubDate>
        </item>
        <item>
            <title>syphilis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=syphilis</link>
            <description>syphilis

see also:

	* safe sex and reducing risk of sexual misadventures
	* sexually transmitted infections (STDs/STIs)

introduction

	* syphilis is a sexually transmitted infections (STDs/STIs) caused by the spirochete bacteria, Treponema pallidum
	* it was relatively common until the widespread use on penicillins in the 1950's when it became rare in Western cultures but has been gradually increasing with increased general sexual promiscuity and drug use in the 1980's but massive campaigns a…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Jan 2026 05:24:23 +0000</pubDate>
        </item>
        <item>
            <title>syringobulbia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=syringobulbia</link>
            <description>syringobulbia

see also:

	* syringomyelia
	* weakness of the lower limb(s) / weak in the knees

Introduction

	* a rare condition in which fluid filled cavities (syrinxes) occupy space in the lower part of the brainstem and can impair neuronal function via a pressure effect similar to that seen in syringomyelia with which it is often associated with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Sep 2024 04:37:54 +0000</pubDate>
        </item>
        <item>
            <title>syringomyelia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=syringomyelia</link>
            <description>syringomyelia

see also:

	* weakness of the lower limb(s) / weak in the knees
	* syringobulbia
	* &lt;https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Syringomyelia-Fact-Sheet&gt;

Introduction

	* syringomyelia is a fluid-filled cyst (called a syrinx) forming within the spinal cord
	* most cases are associated with congenital Chiari malformation
		*  an abnormal condition in which brain tissue extends through foramen magnum and into the spinal canal and obstructs the flow …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Sep 2024 04:39:26 +0000</pubDate>
        </item>
        <item>
            <title>Victoria's Transport Accident Commission and compensation for victims of road trauma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tac</link>
            <description>Victoria's Transport Accident Commission and compensation for victims of road trauma

see also:

	* Victoria's Transport Accident Act 1986 (pdf)
	* TAC and Work Care / Work Safe certificates of capacity
	* trauma

introduction

	* patients involved in road trauma may be eligible for financial compensation for:
		* medical expenses
		* certain allied health expenses such as physiotherapy, podiatry, etc</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 14 Jan 2015 06:15:11 +0000</pubDate>
        </item>
        <item>
            <title>Takotsubo cardiomyopathy (TCM) / stress cardiomyopathy / &quot;broken heart&quot;</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=takotsubo</link>
            <description>Takotsubo cardiomyopathy (TCM) / stress cardiomyopathy / &quot;broken heart&quot;

see also:

	* cardiology
	* acute myocardial infarction (AMI/STEMI/NSTEMI)

introduction

	* 1st described in Japan in 1990 by Sato et al.
	* transient cardiomyopathy which appears to be caused by persistent high levels of circulating catecholamines as a result of an acute stress reaction such as the sudden death of a loved one</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 16 May 2025 09:47:35 +0000</pubDate>
        </item>
        <item>
            <title>oseltamivir (Tamiflu)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tamiflu</link>
            <description>oseltamivir (Tamiflu)

see also:

	* influenza
	* zanamivir (Relenza)
	* Western Health influenza pandemic information
	* Tamiflu Data Sheet approved by NZ Medsafe 3th March 2009

ASID/TSANZ guidelines and position statement 18th June 2009 relating to H1N1 influenza 09 (human swine flu)

	* see EMJA June 2009 - ASID/TSANZ guidelines
	* Australasian Society for Infectious Diseases (ASID)
	* Swine Influenza Task Force of the Thoracic Society of Australia and New Zealand (TSANZ)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 08 Jul 2009 03:44:01 +0000</pubDate>
        </item>
        <item>
            <title>tamoxifen</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tamoxifen</link>
            <description>tamoxifen

see also:

	* breast cancer
	* oestrogens
	* antioestrogens

Introduction

	* Tamoxifen is the oldest and most-prescribed selective estrogen receptor modulator (SERM) used to treat breast cancer since its approval by US FDA in 1998. 
	* Tamoxifen won't work on hormone-receptor-negative breast cancer</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 22 Aug 2025 23:32:29 +0000</pubDate>
        </item>
        <item>
            <title>skin sun tanning aides</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tanning</link>
            <description>skin sun tanning aides

see also:

	* dermatology
	* melanoma

Introduction

	* Australia has banned most of these aids, especially UV tanning clinics which obviously will increase skin ageing and cancer risks

Intranasal Melanotan-II

	* illegal agent in Australia, not approved by the TGA</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Jan 2025 23:33:56 +0000</pubDate>
        </item>
        <item>
            <title>tapentadol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tapentadol</link>
            <description>tapentadol

see also:

	* pain, analgesia and analgesics
	* opiates and opioids
	* tramadol
	* Opioid dose converter app

introduction

	* synthetic opiate-like analgesic similar to tramadol invented in the late 1980's and approved by TGA in Australia in 2010 as an S8 controlled drug
	* as with tramadol it has a dual mode of action as an agonist of the μ-opioid receptor and as a norepinephrine reuptake inhibitor (NRI)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 07 Feb 2024 06:12:23 +0000</pubDate>
        </item>
        <item>
            <title>tardive dyskinesia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tardive_dyskinesia</link>
            <description>tardive dyskinesia

see also:

	* extrapyramidal reactions such as oculogyric crisis, dystonic reactions, akathisia

introduction

	* an irreversible, disabling movement disorder usually due to long term use of medications which block dopamine D2 receptors such as:
		* anti-emetics such as metoclopramide (Maxolon)
		* phenothiazines including prochlorperazine (Stemetil) and chlorpromazine (Largactil)
		* butyrophenone type antipsychotic agents including haloperidol and droperidol (Droleptan)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 May 2014 07:33:35 +0000</pubDate>
        </item>
        <item>
            <title>taste and smell</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=taste_smell</link>
            <description>taste and smell

see also:

	* neurology
	* Cranial nerve examination

Introduction

	* taste (gustation) and smell (olfaction) are very much linked in our experiences and much of what we taste is actually from our smell sensors with modulation from trigeminal nerve stimulation (registering texture, pain, and temperature) and chemesthesis of mucosa which provides coolness (eg. menthol), hotness (eg. pungency), tingling/numbness (eg. Sichuan pepper), astringency (tannins or calcium oxalate as in …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Mar 2026 12:55:15 +0000</pubDate>
        </item>
        <item>
            <title>Tazocin (piperacillin + tazobactam)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tazocin</link>
            <description>Tazocin (piperacillin + tazobactam)

see also:

	* antibiotics

introduction

	* broad spectrum parenteral antibiotic + beta-lactamase inhibitor reserved for defined uses for serious sepsis such as:
		* ascending cholangitis and other intra-abdominal sepsis
		* urosepsis resistant to other antibiotics</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 May 2013 08:02:49 +0000</pubDate>
        </item>
        <item>
            <title>tuberculosis (TB)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tb</link>
            <description>tuberculosis (TB)

see also:

	* infectious diseases
	* mycobacteria
	* the persistent cough
	* back pain in the ED
	* World Health Organisation (WHO) guide and updates on TB
	* NZ govt TB literature
	* EMedicine article on TB
	* Western Health policies (intranet accessible only):
		* TB (pdf)
		* TB - General information for staff (pdf)


Introduction

	* tuberculosis is caused by the bacterial organism Mycobacterium tuberculosis (MTB) causing a generally slowly progressive chronic infection ma…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 11 Oct 2024 07:39:09 +0000</pubDate>
        </item>
        <item>
            <title>tenesmus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tenesmus</link>
            <description>tenesmus

see also:

	* diverticulitis

Introduction

	* tenesmus is the sensation of needing to pass stool often associated with pain, cramps and straining despite little stool being passed
	* it is usually associated with inflammation of the rectum (proctitis) or sigmoid colon, or</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Jun 2018 12:23:35 +0000</pubDate>
        </item>
        <item>
            <title>torsion of testes</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=testes_torsion</link>
            <description>torsion of testes

see also:

	* epididymo-orchitis
	* herniae
	* acute scrotal pain or swelling
	* Western Health surgery pathway - the painful testicle 

introduction

	* intratunical torsion of the testes is a surgical emergency as infarction of the testes increases with time, and with durations exceeding 4 hours from onset, prognosis becomes poor
	* patients with suspected torsion of testes are usually triaged as code 2 and surgical consult sought</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 20 Aug 2017 00:17:10 +0000</pubDate>
        </item>
        <item>
            <title>tetanus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tetanus</link>
            <description>tetanus

	* RCH guideline - tetanus prophylaxis
	* RCH guideline - tetanus-prone wounds
	* clinically important bacteria

at risk patients

	* those who have never been vaccinated or vaccination course incomplete or &gt; 10 years ago who have a tetanus prone wound such as:
		* retained foreign body esp. wood
		* contaminated wound
		* compound fracture</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 02 Jul 2022 23:51:01 +0000</pubDate>
        </item>
        <item>
            <title>tetracycline antibiotics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tetracyclines</link>
            <description>tetracycline antibiotics

see also:

	* antibiotics

introduction

	* bacteriostatic, broad spectrum for many Gram +ves, -ves, some anaerobes, rickettsiae, chlamydiae, mycoplasmas, L-forms, some protozoa (eg. amoebae).
		* uses: atypical pneumonia, PID, acne, malaria</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Aug 2011 11:43:41 +0000</pubDate>
        </item>
        <item>
            <title>thalassemia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thalassemia</link>
            <description>thalassemia

see also:

	* malaria
	* anaemia
	* &lt;https://www.cdc.gov/ncbddd/thalassemia/facts.html&gt;
	* Vic. Better Health - thalassaemia

Introduction

	* a group of inherited conditions that cause defective production of haemoglobin
	* the most common is beta thalasemia which is autosomal recessive and thus exists in two forms:
		*  thalassemia minor - heterozygous trait mild form with mild reduction in Hb beta chain production and mild anaemia</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 Oct 2025 02:35:32 +0000</pubDate>
        </item>
        <item>
            <title>therapeutics - risks and benefits of therapies, medications, drugs, etc</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=therapeutics</link>
            <description>therapeutics - risks and benefits of therapies, medications, drugs, etc

See also:

	* evidence based medicine (EBM)

introduction

	*  before we prescribe a treatment, or as a patient, accept a treatment, we should have a reasonable understanding of the expected benefits and the potential risks of that treatment.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 13 Apr 2014 06:31:09 +0000</pubDate>
        </item>
        <item>
            <title>thiopentone</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thiopentone</link>
            <description>thiopentone

see also:

	* barbiturates
	* induction agents for anaesthesia

introduction

	* thiopentone is an ultra-short acting barbiturate primarily used as an induction agent to aid rapid sequence induction (RSI) for emergency intubation
	* iv use only
		* IM use causes pain/necrosis
		* inadvertent intra-arterial injection of thiopentone -&gt; vasospasm

	* consider alternatives if either:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Mar 2009 05:36:34 +0000</pubDate>
        </item>
        <item>
            <title>thoracic surgery</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thoracics</link>
            <description>thoracic surgery

see also:

	* pneumothorax
	* thoracic surgery at Western Health</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 05 Jan 2019 04:41:30 +0000</pubDate>
        </item>
        <item>
            <title>tube thoracostomy for Rx of pneumothorax and haemothorax</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thoracostomy_tube</link>
            <description>tube thoracostomy for Rx of pneumothorax and haemothorax

see also:

	* pneumothorax
	* trauma to the chest
	* links to videos on nearly everything you need to know about chest drains, thoracotomy, underwater seal drainage courtesy of Life In The Fast Lane
	* how to secure the chest tube
	* RCH guideline - intercostal catheter insertion
	* The University of Queensland Portal for Chest Tube Insertion

introduction

	* pleural decompression via inserting an intercostal catheter is a core emergency…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 27 May 2018 02:39:59 +0000</pubDate>
        </item>
        <item>
            <title>thrombotic microangiopathy (TMA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombma</link>
            <description>thrombotic microangiopathy (TMA)

see also:

	* acute kidney injury (AKI) / acute renal failure (ARF)
	* microangiopathic hemolytic anemias (MAHAs)

Introduction

	* thrombotic microangiopathy is an uncommon condition which may cause life threatening acute kidney injury (AKI) / acute renal failure (ARF) requiring dialysis

Clinical features

	* intravascular haemolysis on the blood film
	* raised creatinine level with or without</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 08 Sep 2023 09:53:34 +0000</pubDate>
        </item>
        <item>
            <title>thrombocytopenia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombocytopenia</link>
            <description>thrombocytopenia

see also:

	* full blood examination (FBE)
	* thrombocytosis

	* artefectual results are common, and unexpected significantly low platelet counts should be re-checked
	* be alert to the possibility of TTP or heparin-induced thrombocytopenia, as a delay in diagnosis can result in serious morbidity or mortality</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 13 Nov 2025 10:15:32 +0000</pubDate>
        </item>
        <item>
            <title>thrombocytosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombocytosis</link>
            <description>thrombocytosis

see also:

	* full blood examination (FBE)
	* thrombocytopenia

introduction

	* thrombocytosis is defined by an excessive concentration of platelets in the peripheral blood &gt; 500 x 10^9/L
	* primary thrombocytosis may cause increased risk of thrombosis and stroke (CVA) and thus high risk patients are usually treated with long term hydroxyurea</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 13 Sep 2024 01:00:51 +0000</pubDate>
        </item>
        <item>
            <title>thrombolysis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombolysis</link>
            <description>thrombolysis

see:

	* thrombolytics
	* thrombolysis in AMI
	* thrombolysis in PE
	* thrombolysis in stroke
	* intra-arterial thrombolysis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 29 May 2014 06:06:01 +0000</pubDate>
        </item>
        <item>
            <title>thrombolysis for AMI</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombolysisami</link>
            <description>thrombolysis for AMI

see also thrombolytics, acute myocardial infarction (AMI/STEMI/NSTEMI)

thrombolytic therapy for AMI's:

indications for coronary reperfusion:

	* NB. if coronary re-perfusion is indicated, percutaneous coronary intervention (primary PCI or “hot angioplasty”) is usually the preferred option if available within 2 hours</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 05 Nov 2014 10:16:03 +0000</pubDate>
        </item>
        <item>
            <title>thrombolysis in stroke</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombolysiscva</link>
            <description>thrombolysis in stroke

see also:

	* thrombolytics; 
	* stroke (CVA)
	* ED Mx of stroke
	* The NNT blog: commentary on the International Stroke Trial 3 (‘IST-3’) published in 2012
	* Emedicine article on thrombolysis in stroke
	* LITFL: Why we should be very wary of using clotbusting drugs to treat acute strokes
	* BML Mar 2015: researchers call for re-think on use of Alteplase in stroke - evidence suggests harm outweighs benefit at greater than 3 hrs
	* 2026 AHA consensus guidelines on Mx of i…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 22 Feb 2026 23:07:28 +0000</pubDate>
        </item>
        <item>
            <title>ED Mx of stroke with possible thrombolytic Rx</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombolysiscvamx</link>
            <description>ED Mx of stroke with possible thrombolytic Rx

see also:

	*  stroke (CVA)
	*   ED Mx of stroke

ED triage of the patient with possible stroke

	* if patient is clearly not suitable for thrombolysis in stroke (eg. on warfarin) then see ED Mx of stroke.
	* if patient may be suitable for thrombolysis in stroke such as onset of stroke symptoms within 4.5 hours without seizures, then continue on.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:41:42 +0000</pubDate>
        </item>
        <item>
            <title>Intra-arterial thrombolysis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombolysisia</link>
            <description>Intra-arterial thrombolysis

see also thrombolytics

possible indications:

	* acute non-limb threatening ischaemia in selected patients

regimes used:

	* streptokinase 2,500-5,000U/hr i/arterial infusion, with catheter tip at the occlusion until patency is restored, or,</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Sep 2008 11:31:15 +0000</pubDate>
        </item>
        <item>
            <title>thrombolysis in Mx of PE</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombolysispe</link>
            <description>thrombolysis in Mx of PE

see also:

	* thrombolytics
	* ED Mx of pulmonary embolism (PE)

aims of Rx:

	* accelerate clot lysis to reduce acute pulmonary hypertension &amp; RVF and hopefully prevent death in the acute period

the massive PE death spiral

	* “PE is notorious for causing patients to go from looking fine to PEA arrest within minutes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 06 Dec 2019 22:21:01 +0000</pubDate>
        </item>
        <item>
            <title>thrombolytics</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombolytics</link>
            <description>thrombolytics

see also:

	* pharmacology main index
	* cardiology
	* thrombolysis
	* thrombolysis in AMI
	* thrombolysis in PE
	* thrombolysis in stroke
	* intra-arterial thrombolysis
	* Heart.org thrombolytics (pdf)
	* LITFL

thrombolytic agents:

	* also called fibrinolysis or fibrinolytics

	* LMWH such as enoxaparin (30mg iv bolus, then 1mg/kg s/c bd), appears to be better than unfractionated heparin as an adjunct to thrombolysis in AMI although does increase major bleed rates, but net bene…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 10 Sep 2023 06:17:14 +0000</pubDate>
        </item>
        <item>
            <title>thrombophilia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombophilia</link>
            <description>thrombophilia

see also:

	* deep venous thrombosis (DVT)
	* pulmonary embolism (PE)

introduction

	* thrombophilia is a term generally used for persons with a hereditary risk of venous thrombosis due to hypercoagulability
	* such patients are at increased risk of venous thrombosis such as:
		* deep venous thrombosis (DVT)
		* pulmonary embolism (PE)
		* upper limb DVT
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 19 Oct 2023 21:54:34 +0000</pubDate>
        </item>
        <item>
            <title>thrombophlebitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombophlebitis</link>
            <description>thrombophlebitis

see also:

	* Mx of lower limb DVT

introduction

	* thrombophlebitis is thrombosis of a vein with associated inflammation and if infective, is called septic thrombophlebitis
	* sterile thrombophlebitis of the peripheral veins is painful and causes local erythema and tenderness but generally settles without serious sequelae, although sometimes the thrombosis can extend into deeper veins resulting in a</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 04 Jun 2021 22:57:42 +0000</pubDate>
        </item>
        <item>
            <title>thrombosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thrombosis</link>
            <description>thrombosis

see:

	* coagulation pathways
	* anticoagulants
	* deep venous thrombosis (DVT)
	* thrombophlebitis
	* thrombophilia
	* pulmonary embolism (PE)
	* pulmonary vein thrombosis (PVT)
	* splanchnic vein thrombosis (SVT) including portal V,  mesenteric V, Budd-Chiari syndrome
		*  Budd-Chiari syndrome (BCS)

	* cerebral dural venous sinus thrombosis (CVST)
	* thrombosis with thrombocytopenia syndrome (TTS / VITT / VIPIT)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 03 Aug 2023 05:32:19 +0000</pubDate>
        </item>
        <item>
            <title>thyroid physiology and hormones</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thyroid</link>
            <description>thyroid physiology and hormones

see also:

	* endocrinology
	* hyperthyroidism
	* hypothyroidism
	* American Thyroid Association guidelines

introduction

	* the hypothalamus releases thyrotropin releasing hormone (TRH)
	* TRH stimulates the anterior pituitary to release thyroid stimulating hormone (TSH) 
	* TSH stimulates the thyroid to produce thyroxine (T4)
	* T4 is converted peripherally to T3 which is more active than T4</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 11 May 2014 12:44:52 +0000</pubDate>
        </item>
        <item>
            <title>thyroiditis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thyroiditis</link>
            <description>thyroiditis

see also:

	* thyroid physiology and hormones
	* hyperthyroidism
	* Mx of a low TSH
	* thyroid storm
	* Graves disease
	* thyroid cancer

Introduction

	* thyroiditis is an inflammatory condition of the thyroid
	* inflammation resolves in 95% within 12-18 months although may result in permanent hypothyroidism
		*  most patients with Hashimotos' thyroiditis, radiation</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 25 Oct 2021 02:04:24 +0000</pubDate>
        </item>
        <item>
            <title>thyroid storm</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thyroid_storm</link>
            <description>thyroid storm

see also:

	* thyroid physiology and hormones
	* hyperthyroidism
	* Mx of a low TSH

Introduction

	* thyroid storm is a rare acute medical emergency with a high mortality if untreated
	* occurs in 1-2% of hospitalized patients with hyperthyroidism
	* 80% are women
	* 80% are aged 20-50 years
	* It is mostly seen in patients with</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 02 Feb 2020 14:52:26 +0000</pubDate>
        </item>
        <item>
            <title>thyroxine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=thyroxine</link>
            <description>thyroxine

see thyroid physiology and hormones</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 11 May 2014 12:46:12 +0000</pubDate>
        </item>
        <item>
            <title>transient ischaemic attack (TIA)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tia</link>
            <description>transient ischaemic attack (TIA)

see also:

	* neurology
	* stroke (CVA)
	* atrial fibrillation
	* calculators:
		* CHADS2 Score for Atrial Fibrillation Stroke Risk
		* CHA2DS2-VASc Score for Atrial Fibrillation Stroke Risk
		* ABCD2 Score for TIA

	* NICS care bundle of documents to assist in the ED management of TIA and stroke
	* AHA/ASA Guidelines - Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack
	* European Heart Journal Guidelines for the m…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:36:33 +0000</pubDate>
        </item>
        <item>
            <title>ticagrelor (Brilinta)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ticagrelor</link>
            <description>ticagrelor (Brilinta)

see also:

	* antiplatelet agents

introduction

	* a reversible adenosine diphosphate P2Y12 inhibitor marketed in Australia in 2011 as Brilinta 90mg tablets
	* approved on PBS from August 2012 following the PLATO trial which showed in patients with acute coronary syndromes including STEMI:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 25 Apr 2025 00:34:55 +0000</pubDate>
        </item>
        <item>
            <title>tick-borne relapsing fever</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tickrelapsingfever</link>
            <description>tick-borne relapsing fever

see also:

	* clinically important bacteria
	* Lyme disease
	* louse-borne relapsing fever

Introduction

	* a variety of relapsing fever type illnesses spread by Borrelia infected ticks (mainly in soft bodied ticks)
	* Not to be confused with louse-borne relapsing fever or Lyme disease

Aetiology

	* various Borrelia species cause these illnesses:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 May 2025 07:27:30 +0000</pubDate>
        </item>
        <item>
            <title>ticks in Australia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ticks</link>
            <description>ticks in Australia

see also:

	* insect bites and stings
	* toxinology

introduction

	* ticks are blood sucking, external parasites which belong to the order Acarina (which also contains mites) and are related to spiders and scorpions
	* globally, only mosquitoes spread more human and animal diseases than ticks</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 10 Oct 2025 00:03:10 +0000</pubDate>
        </item>
        <item>
            <title>tinea fungal infections</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tinea</link>
            <description>tinea fungal infections

see also:

	* fungi
	* antifungal agents
	* dermatology
	* scalp and hair conditions

Introduction

	* tinea infections of the skin are caused by a range of fungal dermatophytes
	* skin infections caused by yeasts such as Candida are not included under the tinea umbrella

Major clinical types and organisms</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Feb 2026 10:51:59 +0000</pubDate>
        </item>
        <item>
            <title>tinnitus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tinnitus</link>
            <description>tinnitus

see also:

	* ED Mx of vertigo and BPV
	* endolymphatic hydrops including Meniere's disease

introduction

	* most tinnitus originating in the auditory system is due to a sensorineural hearing loss with resulting dysfunction within the auditory system
		* mostly this is high pitched 
		* Ménière's disease is generally low pitched tinnitus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 17 May 2020 03:03:04 +0000</pubDate>
        </item>
        <item>
            <title>whooshing or pulsatile tinnitus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tinnitus_pulsatile</link>
            <description>whooshing or pulsatile tinnitus

see also:

	* ED Mx of vertigo and BPV
	* endolymphatic hydrops including Meniere's disease

introduction

	* most tinnitus originating in the auditory system is due to a sensorineural hearing loss with resulting dysfunction within the auditory system
		* mostly this is high pitched 
		* Ménière's disease is generally low pitched tinnitus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 17 May 2020 02:56:06 +0000</pubDate>
        </item>
        <item>
            <title>TMJ dislocation / mandibular dislocation / dislocated jaw</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tmj_dislocation</link>
            <description>TMJ dislocation / mandibular dislocation / dislocated jaw

see also:

	* temporomandibibular joint disorders

Introduction

	* dislocation of the TMJ is a relatively common presentation to the ED 

Aetiology

	* seizures
	* excessive opening of the jaw such as when yawning or in oral sex</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 26 Apr 2025 04:09:33 +0000</pubDate>
        </item>
        <item>
            <title>temporomandibibular joint disorders</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tmj_disorders</link>
            <description>temporomandibibular joint disorders

see also:

	* faciomaxillary
	* TMJ dislocation / mandibular dislocation / dislocated jaw

Introduction:

	* The TMJ is susceptible to all the afflictions of other joints. Conversely, there are no articular conditions unique to the jaw joint. The same rules apply to the masticatory muscles.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 26 Apr 2025 04:04:21 +0000</pubDate>
        </item>
        <item>
            <title>tonsillectomy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tonsillectomy</link>
            <description>tonsillectomy

see also:

	* ears, nose and throat surgery (ENT)

Introduction

	* the tonsils and adenoids form part of the first-line defenses against inhaled or ingested pathogens
	* they tend to enlarge substantially in early childhood especially after age 5yrs and can be prone to recurrent streptococcal bacterial infections, viral infections such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 13 Dec 2024 04:45:11 +0000</pubDate>
        </item>
        <item>
            <title>post-tonsillectomy bleeding</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tonsillectomy_bleed</link>
            <description>post-tonsillectomy bleeding

see also:

	* ears, nose and throat surgery (ENT)
	* tonsillectomy
	* RVEEH clinical practice guideline:
		* Post Tonsillectomy Bleeding (pdf)


Introduction

	* bleeding after tonsillectomy can be life threatening and most patients should be admitted to hospital for at least 24hrs of observation (some with resolved secondary bleeds and no red flags may be managed at home closely observed)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 13 Dec 2024 04:18:34 +0000</pubDate>
        </item>
        <item>
            <title>tonsillitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tonsillitis</link>
            <description>tonsillitis

see also:

	* EBV / glandular fever / infectious mononucleosis

introduction

	* most cases of inflamed tonsils and pharyngitis even with purulent exudate are viral and are often difficult to distinguish clinically from Group A Streptococcal infections
	* Streptococcal infections are more common in those aged 3yrs to 13yrs and less so in older children and adults</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 14 Aug 2018 13:48:03 +0000</pubDate>
        </item>
        <item>
            <title>thoracic outlet syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tos</link>
            <description>thoracic outlet syndrome

see also:

	* subclavian steal syndrome
	*  pectoralis minor compression of axillary vein 
		*  &lt;https://www.sciencedirect.com/science/article/pii/S0741521407001498&gt;


Introduction

	* thoracic outlet syndrome is an uncommon pathology where either nerves, artery, or veins to the arm or head are compressed after they leave the thoracic outlet</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Jan 2026 10:18:02 +0000</pubDate>
        </item>
        <item>
            <title>touch</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=touch</link>
            <description>touch

see also:

	* paraesthesiae or numbness
	* pain
	* neurology

Introduction

	* light touch is the sensation arising from activation of touch-sensing low-threshold mechanoreceptors (LTMRs) nerve cells via activation of various classes of mechanoreceptors detecting stretch, skin movement, compression, vibration or hair fiber deflection</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 23 Feb 2026 03:44:43 +0000</pubDate>
        </item>
        <item>
            <title>toxicology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=toxicology</link>
            <description>toxicology

	* internet links:
		* Austin Hospital Toxicology guidelines smartphone app (free download)
		* VicTAG Emergency and Life Saving Medicine Register - antidotes registry, etc
		* Micromedex Poisons Index - Victorian hospitals intranet access via IP
		* MIMS via IP address no logon needed within Western Health
		* MIMS Drug database - requires password
		* Toxbase - UK-based extensive poisons database
		* ToxINZ - Australasian toxicology and toxinology database - requires annual subscri…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Jan 2026 00:55:30 +0000</pubDate>
        </item>
        <item>
            <title>toxic worms - hammerhead worms</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=toxic_worms</link>
            <description>toxic worms - hammerhead worms

see also:

	* toxinology
	* &lt;https://australian.museum/learn/animals/worms/shovel-headed-garden-worm/&gt;

Introduction

	* Bipalium kewense (“hammerhead worms” or Shovel-headed Garden Flatworm or land planarians) are an invasive pest originating in the closed forests of Indo-China / Vietnam
	* they are 10-20cm long with a hammerhead appearance</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 Dec 2023 21:53:33 +0000</pubDate>
        </item>
        <item>
            <title>toxinology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=toxinology</link>
            <description>toxinology

see also:

	* animal bites in Australia
	* insect bites and stings
	* ticks in Australia
	* envenomation and bites - page still in construction
	* Australian tiger and brown snake bites
	* spider bites in Australia
	* redback spider bites
	* funnel web spider bites (atraxis)
	* food poisoning
	* scombroid histamine food poisoning due to spoiled fish
	* ciguatera toxin reef fish food poisoning
	* blue-green algae (BGA) toxins in waterways
	* Perfluoroalkyl and polyfluoroalkyl substanc…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 Dec 2023 21:26:47 +0000</pubDate>
        </item>
        <item>
            <title>toxoplasmosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=toxoplasmosis</link>
            <description>toxoplasmosis

see also:

	* parasites
	* &lt;https://www.cdc.gov/toxoplasmosis/about/&gt;

Introduction

	* Toxoplasma gondii was discovered in 1908 and is one of the most successful global parasites which appears to be primarily spread by oocytes shed in cat faeces
	* cats appear to be the definitive host and the only host capable of shedding oocytes</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 07 Jan 2026 22:56:21 +0000</pubDate>
        </item>
        <item>
            <title>Alkali ingestion</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tox_alkalis</link>
            <description>Alkali ingestion

see also toxicology

see RCH guideline - alkali poisoning</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Sep 2008 11:24:42 +0000</pubDate>
        </item>
        <item>
            <title>Camphor ingestion</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tox_camphor</link>
            <description>Camphor ingestion

see also toxicology

see RCH guideline - camphor poisoning</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Sep 2008 11:38:08 +0000</pubDate>
        </item>
        <item>
            <title>ethanol intoxication/poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tox_ethanol</link>
            <description>ethanol intoxication/poisoning

see also:

	* ethanol (alcohol and alcohol withdrawal)
	* toxicology
	* RCH guidelines - ethanol poisoning in children

the drunk alcoholic in the ED

	* never assume that a patient is just drunk until you have considered all of the following:
		* hypoglycaemia
		* head injury - order a CT scan if decreased conscious state and possible head injury</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 08 Jan 2026 22:47:18 +0000</pubDate>
        </item>
        <item>
            <title>ethylene glycol poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tox_ethylene_glycol</link>
            <description>ethylene glycol poisoning

see also:

	* toxicology
	* methanol poisoning
	* Wikitox

introduction

	* ethylene glycol is used as a car radiator coolant and is not an uncommon agent used in intentional poisoning.
	* one should suspect it as a cause of cases characterised by high anion gap metabolic acidosis with osmolal gap.
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 24 Nov 2024 01:05:56 +0000</pubDate>
        </item>
        <item>
            <title>Eucalyptus and Essential Oil poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tox_eucalyptus</link>
            <description>Eucalyptus and Essential Oil poisoning

see also:

	* toxicology
	* RCH guideline - eucalyptus oil and essential oil poisoning

Introduction

	* ingestions of 15mL or more eucalyptus oil in adults can be fatal within hours, especially if dose is sufficient to cause acute onset seizures 

Mx

	* do not induce vomiting as risk of aspiration and severe chemical pneumonitis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 06 Feb 2026 22:16:43 +0000</pubDate>
        </item>
        <item>
            <title>General Mx of poisonings and overdoses</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tox_general</link>
            <description>General Mx of poisonings and overdoses

see links to specific poisonings and external links

see RCH guideline - initial Mx of paediatric poisonings</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Sep 2008 12:15:29 +0000</pubDate>
        </item>
        <item>
            <title>Hydrocarbon poisoning</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tox_hydrocarbon</link>
            <description>Hydrocarbon poisoning

see toxicology

see RCH guideline - hydrocarbon ingestion</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 25 Sep 2008 11:45:53 +0000</pubDate>
        </item>
        <item>
            <title>tramadol</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tramadol</link>
            <description>tramadol

see also:

	* pain, analgesia and analgesics
	* opiates and opioids
	* tapentadol

introduction

	*  a synthetic, opioid-like, centrally acting analgesic
	*  it is not chemically related to  opiates
	*  it is related to the newer analgesic, tapentadol
	*  believed to act on mu opioid receptors &amp; inhibit reuptake of serotonin &amp; NA in the pain pathways of the CNS which may play the more important part of its actions.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 10 Jul 2019 00:30:19 +0000</pubDate>
        </item>
        <item>
            <title>tranexamic acid (Cyclokapron)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tranexamic_acid</link>
            <description>tranexamic acid (Cyclokapron)

	* avoid in patients with:
		* thrombophilia or thromboembolic disease such as DVT or PE
		* thrombotic stroke risk
		* subarachnoid haemorrhage (SAH)
		* pregnancy
		* lactation
		* age &lt; 15 years
		* severe renal disease
		* severe bruising
		* bleeding in body cavities</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 22 Feb 2017 03:32:14 +0000</pubDate>
        </item>
        <item>
            <title>transcriptome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=transcriptome</link>
            <description>transcriptome

see also:

	* foods that may be toxic or bad for you
	* risk and the perception of risk
	* air pollution and health risks
	* the GIT microbiome
	* genomics
	* metabolome
	* exposome and health
	* proteome

Introduction

	* the transcriptome generally refers to the individual patient's collection of RNA signatures which can be found in the blood or in tissues and which may reflect pathogens, metabolic and hormonal activity, immunologic status, etc</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Aug 2025 00:31:34 +0000</pubDate>
        </item>
        <item>
            <title>transdermal patches</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=transdermal_patches</link>
            <description>transdermal patches

see also:

	* pharmacology main index
	* nitrates including GTN
	* opiates and opioids

introduction

	* transdermal patches can be an effective drug delivery route
	* they deliver medication at a constant rate via the skin into the bloodstream for a prolonged effect. 
	* increasing numbers of medications are becoming available in transdermal patch form.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 15 Nov 2013 01:34:05 +0000</pubDate>
        </item>
        <item>
            <title>transverse myelitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=transverse_myelitis</link>
            <description>transverse myelitis

see also:

	* weakness of the lower limb(s) / weak in the knees
	* &lt;https://www.ninds.nih.gov/disorders/patient-caregiver-education/fact-sheets/transverse-myelitis-fact-sheet&gt;

Introduction

	* transverse myelitis is inflammation of the spinal cord which produces neurological changes often with a transverse band-like sensory deficit.
	* it may be rapidly developing over hours or days and is then called</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Aug 2019 06:25:50 +0000</pubDate>
        </item>
        <item>
            <title>trauma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma</link>
            <description>trauma

	* ED major trauma call
	* Mx of the major trauma patient
	* geriatric trauma - trauma in the elderly
	* rapid sequence induction (RSI) for emergency intubation
	* massive blood transfusions
	* tranexamic acid (Cyclokapron)
	* RCH guideline - major trauma - the primary survey
	* RCH guideline - wound dressings for acute traumatic wounds
	* paediatric head injury
	* adult head injury
	* eye injuries
	* open wounds to neck
	* cervical spine injury
	* thoracic spine trauma
	* lumbar spine t…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 02 Jan 2026 21:52:36 +0000</pubDate>
        </item>
        <item>
            <title>ankle injuries and fractures</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_ankle</link>
            <description>ankle injuries and fractures

see also:

	* orthopaedics in the ED
	* the injured foot
	* DVT, PE, VTE prophylaxis and risk assessment in patients with lower leg immobilization (eg BKPOP plaster for fracture ankle)
	* Phong Tran's - patient information website - sprained ankles
	* Phong Tran's - patient information website - fractured ankles
	* Phong Tran's - orthopaedics website - fracture neck of talus
	* Phong Tran's - orthopaedics website - fracture calcaneum 
	* AO Foundation Surgery Refere…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 09:00:56 +0000</pubDate>
        </item>
        <item>
            <title>blunt aortic injury</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_bluntcvs</link>
            <description>blunt aortic injury

see also:

	* trauma to the chest
	* aortic dissection features and diagnosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 May 2014 06:47:45 +0000</pubDate>
        </item>
        <item>
            <title>ED major trauma call</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_call</link>
            <description>ED major trauma call

see also:

	* trauma

introduction

	* many hospitals implement a “trauma call” process to improve patient outcomes in high risk trauma which is activated when high risk patients are brought into the emergency department or when the ambulance clinician notifies the ED of the imminent arrival of such a patient</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:56:54 +0000</pubDate>
        </item>
        <item>
            <title>trauma to the chest</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_chest</link>
            <description>trauma to the chest

see also:

	* trauma
	* tube thoracostomy for Rx of pneumothorax and haemothorax
	* pneumothorax
	* Blunt trauma to the Heart and Great Vessels
suspected cardiac tamponade
	* early FAST ultrasound scanning is critical in detection of traumatic cardiac tamponade
	* once haemopericardium is detected, look for evidence of tamponade: right atrial and right ventricular collapse</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 06 Jul 2020 00:30:51 +0000</pubDate>
        </item>
        <item>
            <title>facial trauma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_facial</link>
            <description>facial trauma

see also:

	* trauma
	* faciomaxillary

introduction

	* consider possibility of non-accidental injury in young children with facial trauma

amount of force required to cause a fracture in a normal adult:
  bone    force in multiples of gravitational force    nasal bones    30</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 19 Feb 2023 22:55:27 +0000</pubDate>
        </item>
        <item>
            <title>falls from a height</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_falls_height</link>
            <description>falls from a height

see also:

	* trauma

introduction

	* patients presenting after a fall from a height are at high risk of important injuries
	* a fall of 3m or more is an indication for a ED major trauma call
	* patients should be managed as per Mx of the major trauma patient

classic injuries

	* head injury</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 04 Mar 2014 05:55:00 +0000</pubDate>
        </item>
        <item>
            <title>the injured foot</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_foot</link>
            <description>the injured foot

see also:

	* orthopaedics in the ED
	* the painful foot
	* ankle injuries and fractures
	* acute foot drop

introduction

	* foot injuries are common and significant injuries are commonly missed unless actively sort by the treating clinician.
	* delayed diagnosis or misdiagnosis of important injuries can contribute to long term morbidity</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 28 Jan 2020 11:21:51 +0000</pubDate>
        </item>
        <item>
            <title>geriatric trauma - trauma in the elderly</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_geriatric</link>
            <description>geriatric trauma - trauma in the elderly

see also:

	* trauma
	* geriatrics

Introduction

	* most trauma in the elderly are due to:
		* falls
		* motor vehicle accidents, especially as pedestrians
		* burns
		* assaults


More likely to sustain an important injury</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 17 Jun 2019 14:51:15 +0000</pubDate>
        </item>
        <item>
            <title>the injured hand</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_hand</link>
            <description>the injured hand

see also:

	* animal bites
	* cellulitis
	* removal of embedded fish hooks
	* burns
	* paediatric lacerations
	* local anaesthetic agents
	* fractures of the metacarpal
	* fractures and dislocations of the fingers
	* high pressure fluid spray / hydraulic injury

referring patients to the plastics registrar

	* first indicate what YOU think is the diagnosis as this helps set a framework for the receiving doctor's thought processes
	* patient's age, fasting status, occupation and…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 21 Jan 2025 12:05:49 +0000</pubDate>
        </item>
        <item>
            <title>the acutely injured knee in ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_knee</link>
            <description>the acutely injured knee in ED

see also:

	* orthopaedics in the ED
	* dislocation of the knee joint
	* ACL injury and diagnostic tests - wikipedia

introduction

	* be aware that a painful knee may be referred pain from an injured hip - see hip pain, or from L5 and S1 nerve roots which may be impinged as part of sciatica - see back pain in the ED
	* knee injuries can be divided into:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Dec 2015 04:42:34 +0000</pubDate>
        </item>
        <item>
            <title>Mx of the major trauma patient</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_mx</link>
            <description>Mx of the major trauma patient

see also:

	* trauma
	* Vic Trauma Guidelines - Early Trauma Care
	* Vic Trauma Guidelines - trauma in the older patient

introduction

	* the following are general Mx processes for patients who fit criteria for a ED major trauma call

initial Mx in ED

	* call a ED major trauma call to ensure the trauma team is in attendance and a team leader and various team roles are assigned</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 06 Nov 2024 06:03:25 +0000</pubDate>
        </item>
        <item>
            <title>long term outcomes following trauma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trauma_outcomes</link>
            <description>long term outcomes following trauma

see also:

	* trauma
	* EPI Journal - P.Cameron 2016
		* type of injury and severity of injury has less to do with the final outcome than other factors such as age, sex, socioeconomic circumstance, family support, and work status
		* supposedly “moderate” degrees of injury such as a lower limb fracture could take years to recover from</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 May 2016 23:53:41 +0000</pubDate>
        </item>
        <item>
            <title>traveller's diarrhoea</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=travel_diarrhoea</link>
            <description>traveller's diarrhoea

see also:

	* travel medicine
	* the febrile returned traveller
	* gastroenteritis

introduction

causes of traveller's diarrhoea

	* 80% bacterial eg. enterotoxigenic Escherichia coli (ETEC), Salmonella, Campylobacter, etc.
	* up to 20% are parasitic eg. giardiasis, Cryptosporidium, Cyclospora, amoebiasis (usually starts after 6wks or so),</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 29 Dec 2024 00:06:37 +0000</pubDate>
        </item>
        <item>
            <title>the febrile returned traveller</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=travel_fever</link>
            <description>the febrile returned traveller

see also:

	* travel medicine
	* The febrile adult presenting to the ED
	* traveller's diarrhoea
	* Department of Public Health and Tropical Medicine at James Cook University, Townsville
	* The Travel Clinic website
	* The Travel Clinic's fact sheets for travelers
	* &lt;http://www.smartraveller.gov.au/Aust Govt Smart Traveller website&gt;
	* United States Centers for Disease Control and Prevention
	* World Health Organization
	* International Society of Travel Medicine…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 10 Mar 2026 06:00:02 +0000</pubDate>
        </item>
        <item>
            <title>travel insurance</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=travel_insurance</link>
            <description>travel insurance

see also:

	* travel medicine
	* travel insurance providers:
		* Cover More TravelSure insurance
			* does NOT include back or neck conditions, nor alcohol or drug dependency
			* migraines are not automatically included  

		* Medibank - agent for Mondial
			* does NOT include back or neck conditions, nor alcohol or drug dependency</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 25 May 2016 11:14:38 +0000</pubDate>
        </item>
        <item>
            <title>travel medicine</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=travel_med</link>
            <description>travel medicine

see also:

	* Managing jet lag and your body clock
	* travel insurance
	* deep venous thrombosis (DVT)
	* the febrile returned traveller
	* traveller's diarrhoea
	* rabies and related lyssaviruses
	* medical clearance forms for flights are VERY specific and detailed - search the airline's website for this
		* there is usually a simplified special form for pregnant women - search the airline's website for this</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 22 May 2024 10:46:13 +0000</pubDate>
        </item>
        <item>
            <title>tricyclic antidepressants</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tricyclics</link>
            <description>tricyclic antidepressants

see also:

	* tricyclic antidepressant overdose
	* SSRI/SNRI antidepressants
	* depression
	* antidepressants</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Apr 2012 08:17:00 +0000</pubDate>
        </item>
        <item>
            <title>trigeminal neuralgia</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trigeminal_neuralgia</link>
            <description>trigeminal neuralgia

see also:

	* headache
	* a diagnostic approach to the adult with acute headache
	* facial pain

introduction

	* patients with trigeminal neuralgia have pain in the trigeminal nerve distribution presumably as a result of some irritation to the trigeminal nerve
		* 97% have unilateral pain

	* it mainly occurs in those aged &gt; 50yrs (may occur at any age though), women twice as common as men</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 24 Jun 2023 12:40:02 +0000</pubDate>
        </item>
        <item>
            <title>trimethoprim</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=trimethoprim</link>
            <description>trimethoprim

see also:

	* antibiotics

introduction

	* trimethoprim is a folate antagonist antibiotic mainly used to Rx urinary tract infections (UTIs) / cystitis
	* it acts by inhibiting dihydrofolate reductase
	* it is often combined with a sulphonamide antibiotic as co-trimoxazole which now is little used as the sulphonamide component adds little for most infections while increasing risk of hypersensitivity reactions and other adverse effects.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 16 Jan 2012 01:22:54 +0000</pubDate>
        </item>
        <item>
            <title>triptans</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=triptan</link>
            <description>triptans

see also:

	* Mx of acute migraine

introduction

	* triptans are a group of tryptamine-based drugs used to Rx acute migraines 
	* they were introduced in the 1990's and have variable efficacy on aborting a migraine attack, and do not prevent it recurring.
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 22 Dec 2011 09:30:10 +0000</pubDate>
        </item>
        <item>
            <title>troponin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=troponin</link>
            <description>troponin

see also:

	* cardiac markers (troponin)

Introduction

	* troponin is a complex of three regulatory proteins (troponin C, troponin I, and troponin T) that is integral to muscle contraction in skeletal muscle and cardiac muscle, but not smooth muscle. 
		*  Troponin C binds to calcium ions to produce a conformational change in TnI</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 07 Jun 2020 12:24:14 +0000</pubDate>
        </item>
        <item>
            <title>thyroid stimulating hormone (TSH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tsh</link>
            <description>thyroid stimulating hormone (TSH)

see also:

	* hormones
	* thyroid physiology and hormones

introduction

	* TSH is a glycoprotein hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland
	* it stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 11 May 2014 12:33:12 +0000</pubDate>
        </item>
        <item>
            <title>Mx of high TSH</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tsh_high</link>
            <description>Mx of high TSH

see also:

	* hypothyroidism
	* Mx of a low TSH

diagnosis of hypothyroidism

	* persistently high TSH with low free T4 suggest primary hypothyroidism
		* free T3 levels don't add much

	* persistently high TSH (usually to 5-10IU/L) with normal free T4 suggest subclinical primary hypothyroidism</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 27 Jan 2020 05:28:05 +0000</pubDate>
        </item>
        <item>
            <title>Mx of a low TSH</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tsh_low</link>
            <description>Mx of a low TSH

see also:

	* thyroid physiology and hormones
	* hyperthyroidism
	* Mx of high TSH
	* thyroiditis

Introduction

	* thyroid stimulating hormone (TSH or thyrotropin) is produced by the anterior pituitary gland following stimulation by thyrotropin-releasing hormone (TRH) which is produced from the hypothalamus, and TSH secretion is controlled by a negative feedback loop in response to circulating T3 and T4</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Oct 2021 07:17:31 +0000</pubDate>
        </item>
        <item>
            <title>thrombotic thrombocytopenic purpura (TTP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ttp</link>
            <description>thrombotic thrombocytopenic purpura (TTP)

see also:

	* thrombocytopenia
	* Idiopathic thrombocytopenic purpura (ITP)
	* thrombosis with thrombocytopenia syndrome (TTS / VITT / VIPIT)
	* haemolytic uraemic syndrome  (HUS)
	* disseminated intravascular coagulation (DIC)

Introduction

	* 1st described by Eli Moschcowitz in 1924
	* it is a separate entity to haemolytic uraemic syndrome  (HUS) which has a different pathophysiology due to shiga-toxin producing E.coli
	* caused by autoantibodies to …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 08 Sep 2023 10:09:33 +0000</pubDate>
        </item>
        <item>
            <title>thrombosis with thrombocytopenia syndrome (TTS / VITT / VIPIT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tts</link>
            <description>thrombosis with thrombocytopenia syndrome (TTS / VITT / VIPIT)

see also:

	* Covid-19 vaccination
		*  Australian Advisory Group (ATAGI) statement on Astra Zeneca Covid-19 vaccine and TTS
		*  ATAGI statement to healthcare providers April 2021
		*  ACEM Guideline June 2021

	* cerebral dural venous sinus thrombosis (CVST)
	* heparin
	* vaccines
	* platelet factor 4 antibody thrombotic and thrombocytopenia syndromes

Introduction

	* thrombosis with thrombocytopenia syndrome (TTS) is a rare but …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 May 2024 00:23:07 +0000</pubDate>
        </item>
        <item>
            <title>Acute tumour lysis syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tumor_lysis</link>
            <description>Acute tumour lysis syndrome

see also oncology

common oncological settings:

	* haematological malignancies (acute leukaemias &amp; lymphomas)

summary

	* occurs within 1- 5 days of chemo/XRT of rapidly growing tumours that are extremely sensitive to treatment</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 30 Sep 2008 11:59:41 +0000</pubDate>
        </item>
        <item>
            <title>tumour markers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=tumour_markers</link>
            <description>tumour markers

see also:

	* neoplasia / cancer / tumours

Carcinoembryonic antigen (CEA)

	*  Elevated CEA levels are more common in smokers and in patients with inflammatory conditions but rarely exceed 10 ng/mL
	*  While mainly used as a tumour marker for colorectal cancer (bowel cancer), it may also be raised in other tumours such as:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 04 Jan 2026 02:18:21 +0000</pubDate>
        </item>
        <item>
            <title>transurethral prostatic resection (TURP)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=turp</link>
            <description>transurethral prostatic resection (TURP)

see also:

	* benign prostatic hyperplasia (BPH)
	* &lt;https://www.nhs.uk/conditions/transurethral-resection-of-the-prostate-turp&gt;

Introduction

	* transurethral prostatic resection (TURP) is used as one of the surgical managements for benign prostatic hyperplasia (BPH)
	* depending upon the size of the prostate, newer laser modalities such as Holmium laser enucleation of the prostate  (HOLEP) or transurethral laser resection/vaporisation of the prostate …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 27 Jun 2019 04:28:50 +0000</pubDate>
        </item>
        <item>
            <title>Salmonella typhi (typhoid enteric fever)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=typhoid</link>
            <description>Salmonella typhi (typhoid enteric fever)

see also:

	* clinically important bacteria
	* antibiotics
	* shigella
	* paratyphoid enteric fever
	* gastroenteritis
	* the febrile returned traveller
	* traveller's diarrhoea

introduction

	* Salmonella are Gram negative anaerobe clinically important bacteria 
	* certain host factors make humans particularly susceptible to infection, contracted by ingesting contaminated food or water</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 02 Apr 2026 12:44:17 +0000</pubDate>
        </item>
        <item>
            <title>epidemic typhus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=typhus</link>
            <description>epidemic typhus

see also:

	* human louse / lice
	* Salmonella typhi (typhoid enteric fever)

Introduction

	* epidemic typhus is caused by Rickettsia prowazekii which is spread by the human body louse

Epidemiology

	* rare in developed countries
	* most cases occur in areas with poor sanitation, crowding, war or natural disasters where body lice infestations are more common</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 May 2025 07:05:29 +0000</pubDate>
        </item>
        <item>
            <title>ulcerative colitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ulcerative_colitis</link>
            <description>ulcerative colitis

see also:

	* inflammatory bowel disease (IBD)

introduction

epidemiology

	* annual incidence in USA 1 case per 1000 white adults and rising
	* affects all age groups, esp. 3rd &amp; 4th decades of life
	* almost exclusive to industrialised nations with urban &gt; rural</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Mar 2026 21:36:36 +0000</pubDate>
        </item>
        <item>
            <title>wearing underwear - health benefits and adverse effects</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=underwear</link>
            <description>wearing underwear - health benefits and adverse effects

see also:

	* infertility

Introduction

	* apparently up to 20% of Western males go “commando” in public at least some of the time - usually for personally preference
	* data is not available for women but wearing G-strings is near commando in reality</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 04 Mar 2026 13:09:30 +0000</pubDate>
        </item>
        <item>
            <title>undescended testes (cryptorchidism)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=undescended_testes</link>
            <description>undescended testes (cryptorchidism)

see also:

	* acute scrotal pain or swelling
	* groin herniae
	* RCH Kid's Health Info
	* Vic Better Health Channel

introduction

	* 5% of boys are born with an undescended testis, especially premature babies, whilst some boys develop undescended testes from age 1-10yrs as they grow faster than the spermatic cord</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 26 Nov 2013 07:07:12 +0000</pubDate>
        </item>
        <item>
            <title>uricosuric agents</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=uricosurics</link>
            <description>uricosuric agents

see also:

	* uric acid
	* gout
	* pharmacology main index

Introduction

	* Uricosuric agents act directly on renal tubule -&gt; increased uric acid renal excretion;
	* They can also alter plasma binding, distribution &amp; renal excretion of other organic acids;
	* Uric acid in man generally demonstrates net reabsorption in most instances with about 10% of filtered uric acid being excreted, although net secretion is possible;</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 20 Jul 2023 11:40:37 +0000</pubDate>
        </item>
        <item>
            <title>uric acid</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=uric_acid</link>
            <description>uric acid

see also:

	* hyperuricaemia
	* gout
	* uricosuric agents

Introduction

	* uric acid has the formula C5H4N4O3. 
	* uric acid (UA) is the end product of purine metabolism in humans due to the loss of uricase activity by various mutations of its gene during the Miocene epoch, which led to humans and great apes having higher UA levels than other mammals.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 20 Jul 2023 13:06:44 +0000</pubDate>
        </item>
        <item>
            <title>urinary catheters</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=urinary_catheters</link>
            <description>urinary catheters

see also:

	* urology
	* suprapubic catheterisation
	* acute urinary retention
	* Vic. Better Health Channel Patient Information Sheet - urinary catheterisation
	* Continence Foundation of Australia
	* NWM Division of GP's - urinary catheter resources for Mx of Residential Aged Care patients
	* YouTube video on male urinary catherisation procedure - basic nursing asepsis emphasis
	* YouTube video male urinary catherisation procedure - brief video - no sound needed
	* Emedicine…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2025 06:49:49 +0000</pubDate>
        </item>
        <item>
            <title>urinary incontinence</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=urinary_incontinence</link>
            <description>urinary incontinence

see also:

	* urinary urgency and urge incontinence
	* &lt;https://www.racgp.org.au/afp/2017/september/adult-male-stress-and-urge-urinary-incontinence/&gt;

Introduction

	* involuntary loss of control of urine is a common problem and if it is recurrent becomes a major impact on a person's life and socialisation
	* urinary continence requires:
		*  a functional autonomic bladder sphincter</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Jul 2019 10:14:55 +0000</pubDate>
        </item>
        <item>
            <title>acute urinary retention</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=urinary_retention_acute</link>
            <description>acute urinary retention

see also:

	* urology
	* benign prostatic hyperplasia (BPH)
	* the patient unable to pass urine (anuria)
	* AAFP - Mx of acute urinary retention in detail
	* UpToDate

is the patient in retention?

	* failed void and bladder volume &gt; 300mL confirmed with &gt; 400mL drained on catheterisation
	* see the patient unable to pass urine (anuria)

why are they in retention?

	* benign prostatic hyperplasia (BPH)
		* most common cause of AUR in older men</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Sep 2025 07:37:39 +0000</pubDate>
        </item>
        <item>
            <title>urinary urgency and urge incontinence</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=urinary_urgency</link>
            <description>urinary urgency and urge incontinence

see also:

	* urology
	* &lt;https://www.racgp.org.au/afp/2017/september/adult-male-stress-and-urge-urinary-incontinence/&gt;

Introduction

	* urinary urgency is a sudden, compelling urge to urinate and if uncontrollable, may cause urge incontinence
	* changes in afferent evoked reflexes appear to be important in causing this symptom</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 15 Jul 2019 18:53:09 +0000</pubDate>
        </item>
        <item>
            <title>urolithiasis / renal stones / renal calculi</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=urolithiasis</link>
            <description>urolithiasis / renal stones / renal calculi

see also:

	* renal colic
	* nephrocalcinosis
	* urinary tract infections (UTIs) / cystitis
	* acute pyelonephritis
	* gout
	* calcium

Types of urinary calculi

	* 75% are composed of calcium with oxalate and/or phosphate
	* 10% are urate stones (radio-lucent)
	* 10% are struvite stones
	* 90% are radio-opaque</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 28 Jan 2026 10:38:18 +0000</pubDate>
        </item>
        <item>
            <title>urology</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=urology</link>
            <description>urology

	* renal colic
	* androgen deficiency - the male menopause
	* suprapubic catheterisation
	* urinary catheters
	* acute urinary retention
	* acute scrotal pain or swelling
	* torsion of testes
	* epididymo-orchitis
	* diseases and injuries of the penis
	* penile trauma / fractured penis
	* scrotal infusion with saline
	* priapism
	* paraphimosis
	* prostatitis
	* benign prostatic hyperplasia (BPH)
	* transurethral prostatic resection (TURP)
	* acute pyelonephritis
	* urolithiasis / renal…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 10 Jan 2025 03:07:35 +0000</pubDate>
        </item>
        <item>
            <title>urticaria</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=urticaria</link>
            <description>urticaria

see also:

	* anaphylaxis
	* angioedema
	* histamine physiology, receptors and antihistamines
	* RCH guideline - urticaria
	* eosinophilia
	* allergy and hypersensitivity reactions
	* acute rashes in adults
	* erythema multiforme

introduction

	* urticaria or hives is a common pruritic wheal-type generalised rash which has many causes, the most common being viral infections (50%), food allergic reactions (25%), drug reactions (10%), idiopathic (20%), inhalants (2%), bites (1%), conta…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 06 Nov 2025 21:56:32 +0000</pubDate>
        </item>
        <item>
            <title>Ultrasound image artefacts</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=us_artefacts</link>
            <description>Ultrasound image artefacts

see also:

	* ED bedside ultrasound

Introduction:

	* US systems operate on a basis of certain false assumptions relating to the interaction of the sound beam with soft tissue, including:
		* a constant speed of sound in the body of 1540m/s
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 19 Nov 2008 12:45:38 +0000</pubDate>
        </item>
        <item>
            <title>Basics of ultrasound</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=us_basics</link>
            <description>Basics of ultrasound

see also:

	* ED bedside ultrasound
	* &lt;http://highlandultrasound.com&gt;

What is ultrasound?

	* ultrasound is sound whose frequency is above the range of human hearing:
		* human hearing range 20-20,000Hz
		* diagnostic ultrasound 1-20MHz:
			* standards exist up to 15MHz
			* 3MHz commonly used for adult abdominal scans (wavelength = 0.51mm)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 23 Sep 2022 09:36:31 +0000</pubDate>
        </item>
        <item>
            <title>Ultrasound image production</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=us_image</link>
            <description>Ultrasound image production

see also:

	* ED bedside ultrasound

image production:

	* as each pulse is emitted, its line of sight is known accurately &amp; therefore the resulting echoes from sound/tissue interactions along this line are represented on the monitor in accurate spatial position.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 19 Nov 2008 12:37:18 +0000</pubDate>
        </item>
        <item>
            <title>Ultrasound technique</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=us_techniques</link>
            <description>Ultrasound technique

see also:

	* ED bedside ultrasound

Probe manipulation techniques:

get comfortable:

	* operator should be positioned so that forearm &amp; hand are gently resting on the patient, with spine erect &amp; eyes at the level of the system monitor
	* adjust the height of the patient's bed to match your position</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 19 Nov 2008 12:56:08 +0000</pubDate>
        </item>
        <item>
            <title>urinary tract infections (UTIs) / cystitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=uti</link>
            <description>urinary tract infections (UTIs) / cystitis

see also:

	* acute pyelonephritis
	* renal colic
	* interstitial cystitis
	* prostatitis
	* RCH guideline - UTI
	* Healthy.io / Dip.io home urine testing using smartphone colorimeter  app

introduction

	* UTI's are common presentations, particularly in:
		* children with vesicoureteric reflux
		* women, especially post-coital
		* diabetics
		* following urethral instrumentation (eg. gynae surgery, IDC)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 23 Oct 2025 22:06:36 +0000</pubDate>
        </item>
        <item>
            <title>uveitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=uveitis</link>
            <description>uveitis

see also:

	* ophthalmology
	* episcleritis
	* LITFL pictorial blog on uveitis 

acute anterior uveitis (AAU)

	* accounts for 80% of cases of uveitis
	* classic triad of eye pain, redness and photophobia
	* up to 50-60% patients in western countries may have HLA-B27 and these patients tend to have 1st presentation at age 20-40yrs, whereas B27 negative patients tend to have 1st presentation 30-50yrs.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 14 Feb 2026 09:39:06 +0000</pubDate>
        </item>
        <item>
            <title>ultraviolet light exposure (UV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=uv_light</link>
            <description>ultraviolet light exposure (UV)

see also:

	*  ophthalmology
	*  welder flash burns - UV keratopathy (photo keratitis)
	*  skin cancer

Introduction

	* ultraviolet light spectrum, in increasing energy and thus increasing biologic harmful effects, consists of:
		*  UV-A (400 to 315 nm)
		*  UV-B (315 to 280 nm)
		*  UV-C (280 to 100 nm)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 23 May 2024 00:33:19 +0000</pubDate>
        </item>
        <item>
            <title>vaccines</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vaccines</link>
            <description>vaccines

see also:

	* microbiology

Introduction

	* vaccines are man made substances which are designed to elicit an immune response against certain pathogens
	* they may be:
		*  a live attenuated pathogen which causes a relatively asymptomatic infection yet creates a broader immune response against similar but more pathogenic strains (eg. polio)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 05 Jun 2023 03:48:12 +0000</pubDate>
        </item>
        <item>
            <title>the vagus nerve and vagal tone</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vagus</link>
            <description>the vagus nerve and vagal tone

see also:

	* Anatomy of the autonomic nervous system
	* parasympathetics
	* autonomic dysfunction and autonomic neuropathy

introduction

	* the vagus nerve is one of the main parasympathetic nerves

anatomy

	* vagus nerve itself (cranial nerve X):
		* leaves the medulla oblongata between the pyramid and the inferior cerebellar peduncle</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 27 May 2015 06:37:45 +0000</pubDate>
        </item>
        <item>
            <title>sodium valproate (Epilim)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=valproate</link>
            <description>sodium valproate (Epilim)

see also:

	* anticonvulsants
	* migraine
	* bipolar disorder

introduction

	* sodium valproate is an anticonvulsant which is also used to Rx bipolar disorder, and is sometimes used to reduce incidence of migraine attacks
	* it's actions are attributed to:
		* the blockade of voltage dependent Na+ channels</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 24 Nov 2014 10:40:04 +0000</pubDate>
        </item>
        <item>
            <title>vancomycin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vancomycin</link>
            <description>vancomycin

see also:

	* antibiotics for Rx of Staph. aureus
	* meningitis

	* Rapid bolus administration (e.g. over several minutes) may be associated with exaggerated hypotension, including shock, and, rarely, cardiac arrest.
		* should be administered in a dilute solution at a rate not exceeding 500 mg/hour</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 16 Apr 2013 05:50:54 +0000</pubDate>
        </item>
        <item>
            <title>e-cigarette or vaping pulmonary injury</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vaping_lung_injury</link>
            <description>e-cigarette or vaping pulmonary injury

see also:

	* acute dyspnoea / shortness of breath (SOB)
	* Acute Respiratory Distress Syndrome (ARDS)
	* marijuana / cannabis / THC
	* CDC Sept 2019 report

Introduction

	* in July 2019, a cluster of over 50 cases of acute lung injury in association with the use of e-cigarettes or vaping were identified in the USA mainly in young adults using</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 09 Oct 2019 08:38:32 +0000</pubDate>
        </item>
        <item>
            <title>varicella-zoster virus (chickenpox/shingles)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=varicella</link>
            <description>varicella-zoster virus (chickenpox/shingles)

	* RCH guideline - chickenpox
	* RCH patient information sheet (pdf)
	* varicella in pregnancy
	* herpes zoster (shingles)
	* LITFL - pictorial blog on Mx of herpes zoster ophthalmicus / ocular shingles
	* Western Health guideline on infection control for varicella/shingles patients (pdf)
Summary for ED clinicians:
	* isolate patients from others including those in the ED waiting room
	* antivirals for clinical varicella:
		* high risk patients (incl…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 09 Jul 2013 04:41:40 +0000</pubDate>
        </item>
        <item>
            <title>varicella in pregnancy</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=varicella_preg</link>
            <description>varicella in pregnancy

see also:

	* chicken pox / varicella / herpes zoster
	* Obstetrics
	* MJA 2001 position statement on the Mx of varicella in pregnancy
	* CSL guide - ZIG (pdf)
Summary for ED clinicians:
	* antivirals for clinical varicella:
		* high risk patients (incl. pregnant, immunocompromised, age &lt; 28 days, or very unwell) with clinical chickenpox should be considered for</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 22 Oct 2014 06:38:58 +0000</pubDate>
        </item>
        <item>
            <title>vasculitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vasculitis</link>
            <description>vasculitis

see also:

	* collagen vascular disorders

introduction

	* vasculitis is inflammation of the blood vessels (usually the term is applied to arterial system rather than venous which tend to fall under the thrombophlebitis term)
	* systemic vasculitis may be acute, subacute or chronic, and may cause widespread organ damage from either local bleeding, thrombosis or ischaemia, and generally only causes inflammation in certain sizes of vessels depending upon the pathology.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jun 2023 02:20:12 +0000</pubDate>
        </item>
        <item>
            <title>vascular surgery</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vasc_surgery</link>
            <description>vascular surgery

see also:

	* abdominal aortic aneurysm (AAA)
	* aortic dissection
	* thrombosis of the aorta
	* peripheral vascular disease (PVD or PAD)
	* acute limb ischaemia

podcasts and other resources

	* Video podcast - Limb Threatening Emergencies by Jeff Eppler (22min)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 12 Apr 2023 06:28:41 +0000</pubDate>
        </item>
        <item>
            <title>vasodilators</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vasodilators</link>
            <description>vasodilators

see also:

	* nitrates including GTN
	* antihypertensives

introduction

	* vasodilators are medications which relax the smooth muscle in blood vessels, and generally will result in lower blood pressure
	* those which primarily act on the venous side will reduce pre-load on the heart</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Oct 2013 07:33:55 +0000</pubDate>
        </item>
        <item>
            <title>argipressin (vasopressin / ADH)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vasopressin</link>
            <description>argipressin (vasopressin / ADH)

see also:

	* vasopressors
	* inotropes
	* vasopressin receptor antagonists
	* hormones

introduction

	* vasopressin (antidiuretic hormone or ADH) is a vasopressor (ie. causes vasoconstriction), and is also used in the management of diabetes insipidus and oesophageal variceal bleeding.
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 18 Dec 2017 04:33:07 +0000</pubDate>
        </item>
        <item>
            <title>vasopressin receptor antagonists</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vasopressin_antagonists</link>
            <description>vasopressin receptor antagonists

see also:

	* argipressin (vasopressin / ADH)

introduction

	* vasopressin-V2 receptor antagonists have been used to Rx:
		* dilutional hyponatraemia
		* volume overload in congestive cardiac failure
		* reducing rate of progression of ADPKD


vasopressin-V2 receptor antagonists</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 02 Jan 2013 09:42:49 +0000</pubDate>
        </item>
        <item>
            <title>vasopressors</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vasopressors</link>
            <description>vasopressors

see also:

	* inotropes
	* alpha adrenergic agonists
	* sympathomimetics

introduction

	* vasopressors increase vascular tone, resulting in raised mean arterial pressure (MAP), and systemic vascular resistance.
	* inotropes are drugs that increase the force and velocity of myocardial contraction resulting in increased contractility and stroke volume, and therefore cardiac output.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 12 Apr 2012 11:14:12 +0000</pubDate>
        </item>
        <item>
            <title>vasovagal syncope / neurocardiogenic syncope</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vasovagal_syncope</link>
            <description>vasovagal syncope / neurocardiogenic syncope

see also:

	* syncope / near syncope

introduction

	* vasovagal syncope is a common and relatively benign cause of syncope which is the most common cause of syncope / near syncope in adolescents and young adults
	* it should be differentiated from more serious causes such as</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 16 May 2019 23:49:16 +0000</pubDate>
        </item>
        <item>
            <title>vecuronium</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vecuronium</link>
            <description>vecuronium

see also:

	* neuro-muscular blockers
	* rapid sequence induction (RSI) for emergency intubation

introduction

	* a non-depolarising competitive acetylcholine antagonist at nicotinic receptors
	* the most commonly used non-depolarising neuromuscular blocking agent (NMBA) in the ED for maintenance of paralysis in intubated patients.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 18 Mar 2009 07:07:25 +0000</pubDate>
        </item>
        <item>
            <title>venous insufficiency of the leg</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=venous_insufficiency</link>
            <description>venous insufficiency of the leg

see also:

	* venous leg ulcers
	* DVT and post-thrombotic syndrome (PTS)
	* varicose_veins

introduction

	* venous obstruction &amp;/or venous valve incompetence results in venous hypertension in the legs which causes:
		* capillary leak and pitting oedema
		* fibrin deposition, erythrocyte and leukocyte sequestration, thrombocytosis, and inflammation which result in hyperpigmentation and subcutaneous fibrosis</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Aug 2013 09:26:56 +0000</pubDate>
        </item>
        <item>
            <title>venous leg ulcers</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=venous_ulcer</link>
            <description>venous leg ulcers

see also:

	* venous insufficiency of the leg
	* DVT and post-thrombotic syndrome (PTS)
	* the diabetic foot - infection or foot ulcers
	* WH policy - Moisture Associated Skin Lesions: Incontinence Associated Dermatitis (doc) - intranet only
	* Western Health Chronic Wound Clinic Referral form - internet accessible for GPs
		* adults with problematic or complicated open wounds &gt; 4wks duration who reside in the WH catchment
		* referrals require form to be faxed


introduction</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 10 May 2017 05:54:07 +0000</pubDate>
        </item>
        <item>
            <title>assisted ventilation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vent</link>
            <description>assisted ventilation

see also:

	* lung protective ventilation to reduce lung injury in ARDS
	* pathophysiology of mechanical ventilation
	* managing ventilator problems
	* Assist-Control Ventilation (ACV)
	* Intermittent Mandatory Ventilation (IMV)
	* Pressure Support Ventilation (PSV)
	* Airway Pressure Release Ventilation
	* the LTV 1200 ventilator

introduction

	* assisted mechanical ventilation (positive pressure ventilation) consists of a variety of techniques and modes which aim to impr…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 21 Dec 2015 06:41:25 +0000</pubDate>
        </item>
        <item>
            <title>Assist-Control Ventilation (ACV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ventacv</link>
            <description>Assist-Control Ventilation (ACV)

see also:

	* assisted ventilation

introduction

	* During ACV, breaths can be triggered by the patient's inspiratory effort or the ventilator. 
	* Each breath is delivered with the set tidal volume and flow. 
	* The work of breathing can be excessive when the peak flow or trigger sensitivity is insufficient</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Apr 2011 06:25:00 +0000</pubDate>
        </item>
        <item>
            <title>Intermittent Mandatory Ventilation (IMV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ventimv</link>
            <description>Intermittent Mandatory Ventilation (IMV)

see also:

	* assisted ventilation
	* Assist-Control Ventilation (ACV)
	* Pressure Support Ventilation (PSV)

introduction

	* During IMV, breaths are delivered at a set rate, tidal volume, and flow (ie, mandatory breaths). In addition, the patient can breathe spontaneously through the ventilator circuit (ie, non-mandatory breaths). Many ventilators synchronize the mandatory breaths with inspiratory effort by the patient, which is called synchronized IMV…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Apr 2011 05:44:50 +0000</pubDate>
        </item>
        <item>
            <title>the LTV 1200 ventilator</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ventltv1200</link>
            <description>the LTV 1200 ventilator

see also:

	* assisted ventilation

introduction

	* the LTV 1200 ventilator is a very versatile portable ventilator suitable for emergency departments and patient transfers.
	* the user interface is not always intuitive and does require some instruction.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 14 Apr 2011 07:03:47 +0000</pubDate>
        </item>
        <item>
            <title>noninvasive positive pressure ventilation (NPPV or NIPPV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ventnppv</link>
            <description>noninvasive positive pressure ventilation (NPPV or NIPPV)

see also:

	* assisted ventilation
	* the LTV 1200 ventilator
	* oxygen
	* hypoxia

introduction

	* NPPV includes CPAP and “BiPAP”
	* usually technique is to use a well fitting mask to the patient which minimises air leaks
	* the ventilator then assists patient breathes by applying extrinsic PEEP (PEEP alone is called CPAP) and optionally an inspiratory pressure (IPAP)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 29 Jul 2014 09:27:35 +0000</pubDate>
        </item>
        <item>
            <title>pathophysiology of mechanical ventilation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ventpathophysiology</link>
            <description>pathophysiology of mechanical ventilation

see also:

	* assisted ventilation

introduction

	* the application of positive pressure ventilation creates changes to the body which may not be beneficial.
	* these adverse effects need to be recognised and mitigated where possible</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 03 Aug 2018 05:48:57 +0000</pubDate>
        </item>
        <item>
            <title>managing ventilator problems</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ventproblems</link>
            <description>managing ventilator problems

see also:

	* assisted ventilation

introduction

	* ventilator alarms deserve immediate attention
	* look at the patient:
		* assess ABC:
			* is the airway in place?
			* is tubing connected?
			* is the chest rising and falling regularly?</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 29 Sep 2014 07:05:02 +0000</pubDate>
        </item>
        <item>
            <title>Pressure Support Ventilation (PSV)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=ventpsv</link>
            <description>Pressure Support Ventilation (PSV)

see also:

	* assisted ventilation
	* chronic obstructive pulmonary disease (COPD)
	* Assist-Control Ventilation (ACV)
	* Intermittent Mandatory Ventilation (IMV)

introduction

	* PSV is a flow-limited mode of ventilation that delivers inspiratory pressure until the inspiratory flow decreases to a predetermined percentage of its peak value. This is usually 25%.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 29 Sep 2014 03:38:15 +0000</pubDate>
        </item>
        <item>
            <title>verapamil (Isoptin)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=verapamil</link>
            <description>verapamil (Isoptin)

see also:

	* calcium channel blockers
	* calcium channel blocker overdose

introduction

	* a phenylalkylamine non-dihydropyridine calcium blocking agent 
	* acts mainly on arteriolar smooth muscle to reduce peripheral vascular resistance as well as having negative inotropic and AV conduction effects

main indications</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 31 Dec 2015 04:28:23 +0000</pubDate>
        </item>
        <item>
            <title>ED Mx of vertigo and BPV</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vertigo</link>
            <description>ED Mx of vertigo and BPV

see also:

	* neurology
	* ears, nose and throat surgery (ENT)
	* anti-emetics
	* central vs peripheral vertigo
		* see HINTS exam for vertigo and stroke

	* Cutting-edge technology helps Eye and Ear patients - Melbourne Neuro-ENT with special interest in vertigo

introduction

	* all vertigo is made worse by moving the head
		* if vertigo lasts &lt; 1 minute after moving the head, this suggests BPV
		* most other causes result in vertigo lasting hours to days</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 30 Apr 2019 06:18:12 +0000</pubDate>
        </item>
        <item>
            <title>Vincent's angina - fusospirochaetal infection of the pharynx and tonsils</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vincents_angina</link>
            <description>Vincent's angina - fusospirochaetal infection of the pharynx and tonsils

see also:

	* ears, nose and throat surgery (ENT)
	* sore throats in adults
	* tonsillitis
	* acute dental pain / dental abscess
	* Lemiere's syndrome
	* Ludwig's angina - floor of mouth infection

Introduction

	* not to be confused with Vincent's gingivitis - fusospirochaetal necrotising gingivitis
	* 1st described by Jean Hyacinthe Vincent and noted the infection was caused by infection with two types of bacteria called…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2024 05:39:57 +0000</pubDate>
        </item>
        <item>
            <title>Vincent's gingivitis - fusospirochaetal necrotising gingivitis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vincents_gingivitis</link>
            <description>Vincent's gingivitis - fusospirochaetal necrotising gingivitis

see also:

	* ears, nose and throat surgery (ENT)
	* sore throats in adults
	* tonsillitis
	* acute dental pain / dental abscess
	* Lemiere's syndrome
	* Ludwig's angina - floor of mouth infection

Introduction

	* not to be confused with Vincent's angina - fusospirochaetal infection of the pharynx and tonsils
	* 1st described by Jean Hyacinthe Vincent and in 1904 noted the infection was caused by infection with two types of bacteri…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Nov 2024 06:13:51 +0000</pubDate>
        </item>
        <item>
            <title>managing violence or the aggressive patient in the ED</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=violence_in_ed</link>
            <description>managing violence or the aggressive patient in the ED

see also:

	* psychiatry and mental health
	* domestic violence
	* rapid sedation of the agitated or aggressive patient in the ED
	* Sedation Assessment Tool (SAT) for Mx of agitated patients in ED
	* searching patients, suspicious behaviour, unknown substance, weapons or crime within the ED
	* use of mechanical restraints

general principles

	* aim for patient co-operation where possible and provide respectful, professional clinical practi…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:33:13 +0000</pubDate>
        </item>
        <item>
            <title>viroids - obelisks</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=viroids</link>
            <description>viroids - obelisks

see also:

	* microbiology
	* antiviral agents
	* prions
	* plasmids
	* viruses

Introduction

	* in contrast to viruses, viroids contain RNA but co-opt eukaryotic host RNA polymerases for their replication and lack protein-coding capacity

Obelisks

	* “obelisks” are heritable viroid circular RNA based (∼1,000 nt) rod-like structures</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 20 Dec 2024 22:32:59 +0000</pubDate>
        </item>
        <item>
            <title>viruses</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=viruses</link>
            <description>viruses

see also:

	* microbiology
	* antiviral agents
	* prions
	* viroids - obelisks - viroid RNA in the mouth and elsewhere?
	* paediatric exanthems
	* pandemics - influenza, coronavirus, Ebola
	* websites:
		* Australian National University Virology website


features of viruses in general:

	* Viruses differ from rickettsiae in that they all must convert to a non-infective 'eclipse phase' form during replication &amp; that the synthetic processes during replication take place in the host cell …</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 01 Aug 2025 14:09:43 +0000</pubDate>
        </item>
        <item>
            <title>vitamin A</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vita</link>
            <description>vitamin A

see also:

	* retinoids
	* vitamin D

introduction

	* although known that eating liver can Rx night blindness since ancient times, vitamin A was discovered in the 1920's
	* a family of compounds known as retinoic acids
	* 2 main forms:
		* pro-vitamin A carotenoids:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Jan 2026 04:07:57 +0000</pubDate>
        </item>
        <item>
            <title>vital signs, clinical deterioration, MET calls, acute illness scoring systems (eg. NEWS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vital_signs</link>
            <description>vital signs, clinical deterioration, MET calls, acute illness scoring systems (eg. NEWS)

see also:

	* Australasian Triage Scale (ATS)

general early warning scores to identify and predict deterioration

NHS National Early Warning Score (NEWS) 2

	* original NEWS was released in 2012 and has become widely used in UK hospitals</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 19 Jan 2018 06:08:13 +0000</pubDate>
        </item>
        <item>
            <title>vitamins</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vitamins</link>
            <description>vitamins

see also:

	* vitamin A
	* thiamine (vitamin B1)
	* riboflavin (vitamin B2)
	* niacin / nicotinic acid / nicotinamide  (vitamin B3)
	* pantothenic acid (vitamin B5)
	* pyridoxine (vitamin B6)
	* biotin
	* vitamin B12 (cobalamin)
	* folic acid / folate
	* vitamin C
	* vitamin D
	* vitamin E
	* vitK

Introduction

	* most micronutrient deficiencies are uncommon in high-income countries, however, certain groups remain at risk, including older adults (vitamin D, B6, choline), pregnant wome…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 10 Mar 2025 05:24:02 +0000</pubDate>
        </item>
        <item>
            <title>thiamine (vitamin B1)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vitb1</link>
            <description>thiamine (vitamin B1)

see also:

	* vitamins

introduction

	* thiamine is an essential vitamin involved in carbohydrate metabolism, acting as a coenzyme in reactions such as the decarboxylation of alpha-keto acids, particularly of pyruvate and alpha-keto-glutarate, and in the direct oxidating pathway of glucose metabolism</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 22 May 2021 06:07:45 +0000</pubDate>
        </item>
        <item>
            <title>riboflavin (vitamin B2)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vitb2</link>
            <description>riboflavin (vitamin B2)

see also:

	* vitamins

introduction

	* riboflavin is a vitamin and is the main component of the cofactors FAD and FMN, and is therefore required by all flavoproteins
	* plays a key role in energy metabolism, and for the metabolism of fats, ketone bodies, carbohydrates, and proteins.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Apr 2014 06:31:32 +0000</pubDate>
        </item>
        <item>
            <title>niacin / nicotinic acid / nicotinamide  (vitamin B3)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vitb3</link>
            <description>niacin / nicotinic acid / nicotinamide  (vitamin B3)

see also:

	* vitamins
	* nicotine and nicotine replacement Rx for smokers

Introduction

	* the normal physiological role of nicotinic acid is as a component of the coenzymes NAD and NADP which are essential for oxidation/ reduction reactions in tissue respiration</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 06 Jan 2026 03:38:05 +0000</pubDate>
        </item>
        <item>
            <title>pantothenic acid (vitamin B5)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vitb5</link>
            <description>pantothenic acid (vitamin B5)

see also:

	* vitamins

introduction

	* animals require pantothenic acid to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats
	* small quantities of pantothenic acid are found in nearly every food, with high amounts in whole-grain cereals, legumes, eggs, meat, royal jelly, avocado, and yogurt</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Apr 2014 07:13:05 +0000</pubDate>
        </item>
        <item>
            <title>pyridoxine (vitamin B6)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vitb6</link>
            <description>pyridoxine (vitamin B6)

see also:

	* vitamins
	* isoniazid overdose

introduction

	* pyridoxine (vitamin B6) is a vitamin which plays a critical role as a cofactor for the production of GABA from glutamic acid.
	* other actions include:
		*  acts as a coenzyme in over 100 enzymatic reactions, gluconeogenesis and glycogenolysis are included in its regulation, hence may lower glucose levels</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 04 Aug 2025 09:57:04 +0000</pubDate>
        </item>
        <item>
            <title>biotin (vitamin B7 / vitamin H / coenzyme R)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vitb7</link>
            <description>biotin (vitamin B7 / vitamin H / coenzyme R)

see also:

	* vitamins

introduction

	* biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis

biotin deficiency

	* biotin deficiency is rare as intestinal bacteria generally produce biotin in excess of the body's daily requirements</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 10 Apr 2014 07:10:34 +0000</pubDate>
        </item>
        <item>
            <title>vitamin B12 (cobalamin)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vitb12</link>
            <description>vitamin B12 (cobalamin)

see also:

	* vitamins
	* folic acid / folate

Introduction

	* a water soluble vitamin which can only be created naturally by bacteria and archaea as these have the enzymes required for its synthesis
	* dietary reference intake for an adult ranges from 2 to 3 µg per day (USA), and 1.5 µg per day (UK)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 11 Dec 2025 02:09:35 +0000</pubDate>
        </item>
        <item>
            <title>vitamin C</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vitc</link>
            <description>vitamin C

see also:

	* vitamins

Introduction

	* also known as ascorbic acid (from “anti-scorbutic agent”)
	* a water soluble vitamin found especially in various fruits and vegetables
	* citrus fruits were used on ships in the late 15th C to combat scurvy</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 26 Jun 2025 00:58:51 +0000</pubDate>
        </item>
        <item>
            <title>vitamin D</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vitd</link>
            <description>vitamin D

see also:

	* calcium
	* calcitonin
	* parathyroid hormone (PTH)
	* bone physiology
	* ultraviolet light exposure (UV)
	* patient information sheets:
		* RCH - rickets (pdf)


introduction

	* Inadequate vitamin D nutrition is associated with impaired intestinal calcium absorption and must be corrected for ingested calcium to be effective. 
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 01 Apr 2026 00:11:12 +0000</pubDate>
        </item>
        <item>
            <title>vitamin E</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vite</link>
            <description>vitamin E

see also:

	* vitamins

Introduction

	* vitamin E is an essential micronutrient

vitamin E supplementation

	* not been proven to reduce risks for chronic diseases
	* may have adverse effects at high doses:
		*  increased risks of prostate cancer, respiratory infections</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 10 Mar 2025 05:18:01 +0000</pubDate>
        </item>
        <item>
            <title>vitiligo</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vitiligo</link>
            <description>vitiligo

see also:

	* dermatology
	* immunodeficiency
	* dermnetnz - vitiligo

introduction

	* vitiligo is an acquired depigmenting disorder in which melanocytes are destroyed, resulting in irregularly shaped white patches on the skin
	* may also affect hair (patches of grey hair leukotrichia) and the retina</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 25 Aug 2014 06:07:56 +0000</pubDate>
        </item>
        <item>
            <title>Victorian medical assistance teams for disaster Mx (VMAT)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vmat</link>
            <description>Victorian medical assistance teams for disaster Mx (VMAT)

see also:

	* welcome to the OzEMedicine Wiki
	* Victorian State health emergency response plan (SHERP)
	* MIMMS courses are regularly ran by Vic. DOH
	* Vic. State Health Emergency Response Plan SHERP</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 23 Apr 2015 06:36:55 +0000</pubDate>
        </item>
        <item>
            <title>Volatile substance abuse</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=volatile_substance_abuse</link>
            <description>Volatile substance abuse

see also:

	* Addiction medicine - drug and alcohol - main index and links
	* drug dependency
	* wikipedia

Volatile Substance Abuse

	* Volatile substance abusers are typically young males although females increasingly involved, occurring esp. in poor socioeconomic areas, and fall into 4 main categories:
		*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 16 Jan 2013 01:47:47 +0000</pubDate>
        </item>
        <item>
            <title>caecal volvulus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=volvulus_caecal</link>
            <description>caecal volvulus

see also:

	* central / periumbilical abdominal pain in the ED
	* sigmoid volvulus
	* Emedicine - cecal volvulus

introduction

	* whilst in most people, the caecum is retroperitoneal and not susceptible to volvulus, in 20% there is a congenital incomplete peritoneal covering which allows a mobile caecum on a mesentery such that it now longer lies in the RIF.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Jul 2016 23:02:16 +0000</pubDate>
        </item>
        <item>
            <title>sigmoid volvulus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=volvulus_sigmoid</link>
            <description>sigmoid volvulus

see also:

	* central / periumbilical abdominal pain in the ED
	* caecal volvulus
	* Emedicine

introduction

	* volvulus occurs when colon twists on its mesenteric axis with a greater than 180-degree rotation, producing obstruction of intestinal lumen and mesenteric vessels
	* the most common location is at the sigmoid (see also</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 23 Jul 2016 23:01:33 +0000</pubDate>
        </item>
        <item>
            <title>vomiting / emesis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vomiting</link>
            <description>vomiting / emesis

see also:

	* anti-emetics

introduction

	* vomiting is a highly non-specific symptom
		*  vomiting with significant abdominal pain suggests an abdominal cause rather than a vestibular or neurologic cause
			*  if there is also a PH of abdominal surgery or a hernia then a</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 21 Jan 2021 02:42:44 +0000</pubDate>
        </item>
        <item>
            <title>The patient with a V-P shunt (VPS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vpshunt</link>
            <description>The patient with a V-P shunt (VPS)

see also:

	* neurosurgery
	* hydrocephalus

Introduction

	* patients with a Ventriculo-Peritoneal shunt in situ have additional clinical issues which need to be considered 
	* in patients presenting with symptoms of shunt malfunction, infection should always be suspected since shunt infection is a serious complication with a great potential for severe morbidity and mortality</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 25 May 2020 02:22:08 +0000</pubDate>
        </item>
        <item>
            <title>V/Q ventilation-perfusion lung scans</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vqlungscans</link>
            <description>V/Q ventilation-perfusion lung scans

see also:

	* radiology
	* Ix of suspected pulmonary embolism (PE)

Introduction

	* V/Q lung scans are performed to help in the diagnosis of pulmonary embolism
	* patient inhales a radioactive gas in the ventilation phase and a special camera is then used to image these results</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 19 Jul 2023 06:32:57 +0000</pubDate>
        </item>
        <item>
            <title>varicose veins</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vvs</link>
            <description>varicose veins

see also:

	* deep venous thrombosis (DVT)
	* vascular surgery

Introduction

	* varicose veins are dilated superficial leg veins with reduced ability to return venous flow to the heart against gravity when standing
	* venous insufficiency occurs when the normal flow of blood from the superficial veins to the heart via the perforating deep veins in the lower limbs is impaired</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Thu, 17 Apr 2025 02:32:35 +0000</pubDate>
        </item>
        <item>
            <title>Von Willebrand's disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=vwd</link>
            <description>Von Willebrand's disease

	* RCH guideline - von Willebrand's disease</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 Sep 2008 05:55:30 +0000</pubDate>
        </item>
        <item>
            <title>the ED waiting room</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=waitroom</link>
            <description>the ED waiting room

see also:

	* left at own risk / absconding patient / missing patient / competence

introduction

	* in an ideal world, the ED wait room would be empty or just have new arrivals
	* unfortunately, patients often experience much longer waits, to the extent that “waiting room medicine” is now becoming almost mandatory in many EDs</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 31 Oct 2016 05:27:34 +0000</pubDate>
        </item>
        <item>
            <title>warfarin</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=warfarin</link>
            <description>warfarin

MUST SEE: general anticoagulation guidelines

see also:

	* anticoagulants
	* Mx of excessive anticoagulation, high INR, or bleeding on warfarin Rx
	* CHA2DS2-VASc score for determining stroke risk in patients with non-valvular AF
	* HAS-BLED bleeding risk scoring tool for anticoagulation Rx
	* atrial fibrillation
	* Mx of DVT
	* Mx of PE
	* INR
	* RCH guidelines - anticoagulation therapy in children

Pharmacology

	* also called coumadin
	* 100% bioavailability given orally as the sod…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 17 Mar 2015 07:58:29 +0000</pubDate>
        </item>
        <item>
            <title>Williams-Beuren syndrome (WBS)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=wbs</link>
            <description>Williams-Beuren syndrome (WBS)

see also:

	* comparison of developmental disorders affecting social development
	* wikipedia Williams syndrome / WBS 

introduction

	* the classic form of WBS is rare, affecting 1 in 7,500 children (although earlier studies suggested 1 in 20,000 live births) and is generally sporadic but some have autosomal dominant transmission</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 28 Oct 2013 07:47:21 +0000</pubDate>
        </item>
        <item>
            <title>weakness of the lower limb(s) / weak in the knees</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=weakness_ll</link>
            <description>weakness of the lower limb(s) / weak in the knees

see also:

	* neurology
	* weakness_UL
	* gait disturbance
	* paraesthesiae or numbness

introduction

	* NB. in a trauma context, spinal cord injury and other traumatic causes need to be considered
	* atraumatic weakness of the legs has a multitude of possible causes and it helps to determine the pattern of weakness:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sat, 27 Dec 2025 21:23:15 +0000</pubDate>
        </item>
        <item>
            <title>wheeze</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=wheeze</link>
            <description>wheeze

see also:

	* stridor
	* noisy breathing
	* lung crepitations
	* stertor
	* snoring
	* obstructive sleep apnoea (OSA)
	* Stridor vs Wheeze vs Stertor and snoring in children (pdf)

Introduction

	* noise during breathing can be of various types depending upon whether awake or asleep and on where the airway obstruction arises
	* wheeze is primarily an expiratory musical sound coming from the lungs but may become biphasic and is usually caused by</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 05 Feb 2019 21:48:49 +0000</pubDate>
        </item>
        <item>
            <title>whole bowel irrigation</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=whole_bowel_irrigation</link>
            <description>whole bowel irrigation

see also:

	* toxicology

introduction

	* a rarely used technique to decontaminate GIT of poisons in certain overdoses - particularly cerrtain dangerous sustained release tablet overdoses
	* usually use:
		* polyethylene glycol (PEG) solution</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Jan 2014 07:18:19 +0000</pubDate>
        </item>
        <item>
            <title>Western Health IRCU ward</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=wh_ircu</link>
            <description>Western Health IRCU ward

see also:

	* respiratory medicine

admission process

	* Admission to IRCU should only occur after the Parent Unit obtains the approval of the Respiratory Physician on ward duty or Respiratory Registrar to establish if transfer to the IRCU is appropriate, prior to transfer. Once the patient is accepted, and a bed is available, the Parent Unit must call 2D staff to prepare equipment</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Oct 2013 06:22:05 +0000</pubDate>
        </item>
        <item>
            <title>Western Health ED tips for common presentations</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=wh_tips</link>
            <description>Western Health ED tips for common presentations

see also:

	* Western Health ED main page
	* Sunshine ED Fast Track

introduction

	* ensure you have read the various orientation documents - see Western Health ED medical orientation
	* discuss with senior Dr in ED within 20-30minutes
	* early bed requests and inpatient referrals - if inpatient team do not respond in a timely manner (eg. 30min), d/w senior ED doctor to escalate to inpatient consultant</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 18 Jan 2026 08:52:13 +0000</pubDate>
        </item>
        <item>
            <title>Ozemedicine wikipedia stats</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=wiki_stats</link>
            <description>Ozemedicine wikipedia stats

top pages by hits

top entry pages

hits by day of week

hits by hour of day

top referrers

top agents

monthly summary</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 28 Sep 2009 11:23:13 +0000</pubDate>
        </item>
        <item>
            <title>Wilson's disease</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=wilsonsdisease</link>
            <description>Wilson's disease

see also:

	* caeruloplasmin
	* copper

Introduction

	*  an autosomal recessive genetic disorder caused by a mutation in ATP7B gene in which excess copper builds up in the body, particularly in the liver, kidneys, eyes and brain (especially in the lenticular nucleus of the basal ganglia, - the putamen and globus pallidus)</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 26 Mar 2023 11:34:19 +0000</pubDate>
        </item>
        <item>
            <title>xanthelasma</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=xanthelasma</link>
            <description>xanthelasma

see also:

	* hyperlipidaemia

Introduction

	* xanthelasma is a condition mainly of the peri-orbital region where cholesterol-rich deposits form under the skin of the eyelids forming yellowish lumps which are usually symmetrical and are especially prevalent on the inner canthus of the upper lids</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Wed, 08 Mar 2023 11:51:59 +0000</pubDate>
        </item>
        <item>
            <title>the lumbosacral spine Xray</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=xr_spinelumbar</link>
            <description>the lumbosacral spine Xray

see also:

	* back pain in the ED
	* CT spine - cervical (Cx), thoracic (Tx) or lumbar (Lx)
	* lumbar spine trauma
	* trauma
	* spondylolisthesis
	* radiology
	* NICS - Lumbar spine imaging in low back pain 2008 (pdf)
	* DFTB How to interpret thoracolumbar spine Xrays

introduction

	* the lumbosacral spine Xray is NOT usually indicated in the ED unless there is significant risk of finding pathology such as:
		* fracture risk?
			* major trauma</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Jan 2019 23:05:35 +0000</pubDate>
        </item>
        <item>
            <title>thoracic spine Xray</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=xr_spinetx</link>
            <description>thoracic spine Xray

see also:

	* the lumbosacral spine Xray
	* thoracic spine trauma
	* CT spine - cervical (Cx), thoracic (Tx) or lumbar (Lx)
	* DFTB How to interpret thoracolumbar spine Xrays</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 07 Jan 2019 23:09:05 +0000</pubDate>
        </item>
        <item>
            <title>yellow fever</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=yellow_fever</link>
            <description>yellow fever

see also:

	* travel medicine
	* viruses
	* WHO fact sheet

introduction

	* occurs in urban and rural areas of Africa and central South America
	* caused by a mosquito-borne flavivirus
	* monkeys are the main reservoir but mosquitoes can spread it from human to human
	*</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 31 Dec 2013 03:19:33 +0000</pubDate>
        </item>
        <item>
            <title>Yersinia including bubonic plague and Yersiniosis</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=yersinia</link>
            <description>Yersinia including bubonic plague and Yersiniosis

see also:

	* clinically important bacteria
	* A historians' view of the bubonic plague

introduction

	* Yersinia are Gram-negative, rod-shaped coccobacillus, a facultative anaerobic bacteria belonging to the enterobacteriaceae family
	* Y. pestis is the organism causing the bubonic plague or Black Death epidemic and thousands of cases each year still occur</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Fri, 08 Aug 2025 09:14:04 +0000</pubDate>
        </item>
        <item>
            <title>Young's syndrome</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=youngs</link>
            <description>Young's syndrome

see also:

	* infertility
	* chronic bronchitis
	* sinusitis
	* ciliopathies

introduction

	* Young's disease or syndrome was 1st noted by Young, a urologist, in 1972, which he called Barry-Perkins-Young syndrome
	* this rare syndrome affects mainly middle aged men born before 1955 and consists of:</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Tue, 12 Dec 2023 12:09:35 +0000</pubDate>
        </item>
        <item>
            <title>zanamivir (Relenza)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=zanamivir</link>
            <description>zanamivir (Relenza)

see also:

	* influenza
	* oseltamivir (Tamiflu)

introduction

	* Relenza is supplied in a circular doublefoil pack called a Rotadisk®. 
		* each Rotadisk contains four regularly spaced doublefoil blisters with each blister containing a powder mixture of 5 mg of zanamivir and 20 mg of lactose.</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 13 Dec 2009 23:32:43 +0000</pubDate>
        </item>
        <item>
            <title>zika virus</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=zika</link>
            <description>zika virus

see also:

	* the febrile returned traveller

introduction

	* a rapidly emerging mosquito borne infection of the tropics caused by the zika virus, a flavivirus.
	* like dengue fever, it is spread by Aedes aegypti, but in addition, by Aedes africanus, Aedes apicoargenteus, Aedes furcifer, Aedes luteocephalus</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 01 Oct 2023 20:36:57 +0000</pubDate>
        </item>
        <item>
            <title>zoonoses</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=zoonoses</link>
            <description>zoonoses

see also:

	* clinically important bacteria
	* viruses
	* parasites
	* brucellosis
	* the febrile returned traveller
	* wikipedia for a full list of zoonoses

introduction

	* a zoonosis is any infectious disease that can be transmitted from animals to humans but is not dependent upon humans for their life cycle
	* diseases like malaria, schistosomiasis, river blindness, and elephantiasis are not zoonotic, even though they may be transmitted by insects or use intermediate hosts vectors…</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Mon, 13 Jan 2025 19:45:37 +0000</pubDate>
        </item>
        <item>
            <title>herpes zoster (shingles)</title>
            <link>https://ozemedicine.com/wiki/doku.php?id=zoster</link>
            <description>herpes zoster (shingles)

see also:

	* varicella-zoster virus (chickenpox/shingles)

Introduction

	* reactivation of the latent varicella virus manifests as herpes zoster (HZ or shingles)
	* neonates with congenital chickenpox are at high risk of HZ during infancy.
	* 25% of unvaccinated people will develop zoster in their lifetime - mostly when their immune system becomes less effective when they age or become immunosuppressed</description>
            <author>anonymous@undisclosed.example.com (Anonymous)</author>
            <pubDate>Sun, 15 Mar 2026 06:36:38 +0000</pubDate>
        </item>
    </channel>
</rss>
