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osteoarthritis

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osteoarthritis [2026/07/22 07:25] – [risk factors] gary1osteoarthritis [2026/08/07 14:24] (current) – [Mx] gary1
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   *joint replacement is a last resort as these generally only last 10-15yrs in younger patients, particularly total knee replacements (TKR)   *joint replacement is a last resort as these generally only last 10-15yrs in younger patients, particularly total knee replacements (TKR)
   *daily glucosamine and chondroitin supplements for 2 years in 45-75 yr olds appears to slow joint space narrowing but no evidence of reduced pain vs placebo(([[http://ard.bmj.com/content/early/2014/01/06/annrheumdis-2013-203954.abstract|BMJ 2014]]))   *daily glucosamine and chondroitin supplements for 2 years in 45-75 yr olds appears to slow joint space narrowing but no evidence of reduced pain vs placebo(([[http://ard.bmj.com/content/early/2014/01/06/annrheumdis-2013-203954.abstract|BMJ 2014]]))
 +  *future potential for purinergic P2 receptor antagonists may have a key role in blocking P2 mediated inflammation(([[https://www.sciencedirect.com/science/article/pii/S235230422500491X?via%3Dihub|2026: Purinergic signaling in osteoarthritis: Mechanistic insights into pathogenesis and therapeutic targeting]]))
osteoarthritis.txt · Last modified: 2026/08/07 14:24 by gary1

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