User Tools

Site Tools


nitrosamines

Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revisionPrevious revision
nitrosamines [2026/09/15 08:26] – [Nitrites] gary1nitrosamines [2026/09/15 08:29] (current) – [Dietary nitrates] gary1
Line 119: Line 119:
               * these are more dose dependent and more likely in those with a FH of migraines               * these are more dose dependent and more likely in those with a FH of migraines
               * the mechanism is thought to be NO stimulation of CGRP release, glutamate, cyclic GMP (cGMP), or S-nitrosylation-mediated changes in ion channel function                * the mechanism is thought to be NO stimulation of CGRP release, glutamate, cyclic GMP (cGMP), or S-nitrosylation-mediated changes in ion channel function 
-        * migraine sufferers appear to have a significantly higher abundance of nitrate-reducing bacteria in their mouths and guts than non-sufferers(([[https://pmc.ncbi.nlm.nih.gov/articles/PMC5080405/|2016: Migraines Are Correlated with Higher Levels of Nitrate-, Nitrite-, and Nitric Oxide-Reducing Oral Microbes in the American Gut Project Cohort]]))+        * **migraine sufferers appear to have a significantly higher abundance of nitrate-reducing bacteria in their mouths and guts than non-sufferers**(([[https://pmc.ncbi.nlm.nih.gov/articles/PMC5080405/|2016: Migraines Are Correlated with Higher Levels of Nitrate-, Nitrite-, and Nitric Oxide-Reducing Oral Microbes in the American Gut Project Cohort]]))
     * **nitrates increase risk of aberrant S-nitrosylation**     * **nitrates increase risk of aberrant S-nitrosylation**
         * this is a chemical process whereby a molecule related to nitric oxide (NO) binds to sulfur (S) atoms within proteins (producing "SNO")         * this is a chemical process whereby a molecule related to nitric oxide (NO) binds to sulfur (S) atoms within proteins (producing "SNO")
nitrosamines.txt · Last modified: 2026/09/15 08:29 by gary1

Donate Powered by PHP Valid HTML5 Valid CSS Driven by DokuWiki