c_af_aetiology
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| c_af_aetiology [2024/06/16 14:02] – gary1 | c_af_aetiology [2026/08/02 07:30] (current) – [Aetiology] gary1 | ||
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| =====Aetiology===== | =====Aetiology===== | ||
| + | *most AF is related to high blood pressure, diabetes, and heart disease | ||
| + | *~22% risk is genetic(([[https:// | ||
| + | * both rare and common genetic variants contribute to AF susceptibility | ||
| + | * > 100 common variants associated with AF | ||
| + | * individually rare, high-impact variants | ||
| + | * protein-altering LMNA variants (PAVs) which encode the nuclear envelope protein Lamin A/C | ||
| + | * these are associated with conduction system disease, AF, ventricular arrhythmias, | ||
| + | * AF is highly prevalent and an early manifestation in LMNA-associated cardiomyopathy | ||
| *[[hyperthyroidism]] | *[[hyperthyroidism]] | ||
| *[[hypothyroidism]] | *[[hypothyroidism]] | ||
c_af_aetiology.txt · Last modified: 2026/08/02 07:30 by gary1