anaemia_irondef
Differences
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| anaemia_irondef [2026/08/07 00:43] – [decreased iron intake or malabsorption] gary1 | anaemia_irondef [2026/08/07 00:44] (current) – [decreased iron intake or malabsorption] gary1 | ||
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| * in mice studies, LOF mutations also result in **reduced levels of DMT1, a key iron-absorbing protein located in the intestinal epithelial cells**(([[https:// | * in mice studies, LOF mutations also result in **reduced levels of DMT1, a key iron-absorbing protein located in the intestinal epithelial cells**(([[https:// | ||
| * found in 14-16% of the general population and 19-20% of the IBD population | * found in 14-16% of the general population and 19-20% of the IBD population | ||
| - | * loss of function of TPC1 ion channels | + | * loss of function of TPC1 ion channels |
| * TCP1 activity influences both the absorption of iron from the plasma membrane and the pH value in endosomes that release iron into the cytosol based on pH value(([[https:// | * TCP1 activity influences both the absorption of iron from the plasma membrane and the pH value in endosomes that release iron into the cytosol based on pH value(([[https:// | ||
anaemia_irondef.txt · Last modified: 2026/08/07 00:44 by gary1