Table of Contents
introduction
biotin deficiency
clinical features
biotin (vitamin B7 / vitamin H / coenzyme R)
see also:
vitamins
introduction
biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis
biotin deficiency
biotin deficiency is rare as intestinal bacteria generally produce biotin in excess of the body's daily requirements
clinical features
alopecia
conjunctivitis
dermatitis
neurologic symptoms
characteristic facial rash and facial fat distribution
angular cheilitis (cracked corners of the mouth)
fetal abnormalities