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yersinia [2025/08/08 09:14] – [Yersinia pestis] gary1yersinia [2026/06/22 23:58] (current) – [Yersinia pestis] gary1
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   *the copy number of its //pla// gene correlates with mortality rate and how soon the person will die (([[https://www.science.org/doi/10.1126/science.adt3880|2025: Attenuation of virulence in Yersinia pestis across three plague pandemics]]))   *the copy number of its //pla// gene correlates with mortality rate and how soon the person will die (([[https://www.science.org/doi/10.1126/science.adt3880|2025: Attenuation of virulence in Yersinia pestis across three plague pandemics]]))
   *30% of human cases  worldwide are now in Madagascar which usually sees ~400 new cases per year after Indian steamships brought the plague there in 1898, and is primarily associated with rural areas and agricultural activity, where maximum abundance of rodents in the fields is observed in July and August, followed by the maximum abundance of fleas from September to November   *30% of human cases  worldwide are now in Madagascar which usually sees ~400 new cases per year after Indian steamships brought the plague there in 1898, and is primarily associated with rural areas and agricultural activity, where maximum abundance of rodents in the fields is observed in July and August, followed by the maximum abundance of fleas from September to November
 +  *//Y. pestis// has been estimated to have diverged from //Y. pseudotuberculosis// some time in the past 50,000 years(([[https://www.nature.com/articles/s41586-026-10540-5|2026: Lethal plague outbreaks in Lake Baikal hunter-gatherers 5,500 years ago]]))
 +  *DNA data suggest that there were two documented outbreak phases impacting the neolithic hunter-gatherer populations around Lake Baikal, Siberia around 5,700 years ago(([[https://www.nature.com/articles/s41586-026-10540-5|2026: Lethal plague outbreaks in Lake Baikal hunter-gatherers 5,500 years ago]]))
   *c1338AD, a new Y. pestis strain presumably from zoonosis spillover infected a trading community from the Silk Road in Kyrgyzstan and this species was to become the ancestral strain of 4 major branches, including the Black Death strain which infected Europe starting in 1346 in Crimea and Europe was particularly vulnerable due to its high rat population and density of living   *c1338AD, a new Y. pestis strain presumably from zoonosis spillover infected a trading community from the Silk Road in Kyrgyzstan and this species was to become the ancestral strain of 4 major branches, including the Black Death strain which infected Europe starting in 1346 in Crimea and Europe was particularly vulnerable due to its high rat population and density of living
   *the Black Death remains the single deadliest pandemic in recorded human history, killing an estimated 30 to 50% of the populations of Europe, Western Asia and Africa as it moved through those regions. Appearing in the 14th century, it re-emerged in waves over more than 500 years, persisting until 1840.   *the Black Death remains the single deadliest pandemic in recorded human history, killing an estimated 30 to 50% of the populations of Europe, Western Asia and Africa as it moved through those regions. Appearing in the 14th century, it re-emerged in waves over more than 500 years, persisting until 1840.
yersinia.txt · Last modified: 2026/06/22 23:58 by gary1

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