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tranexamic_acid [2017/02/22 03:32] – created - external edit 127.0.0.1tranexamic_acid [2026/06/11 00:16] (current) – [trauma] gary1
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     *relative risk of bleeding to death is 0.68 if given within 1 hour of trauma, and 0.79 if given with 1-3hrs of trauma but for some reason appeared to increase mortality from bleeding if given more than 3 hours after death     *relative risk of bleeding to death is 0.68 if given within 1 hour of trauma, and 0.79 if given with 1-3hrs of trauma but for some reason appeared to increase mortality from bleeding if given more than 3 hours after death
     *no differences in complications from vascular occlusion (eg, [[pe]], [[ami]])     *no differences in complications from vascular occlusion (eg, [[pe]], [[ami]])
 +  *a study of its use in surgical patients, 60% of whom had cancer showed no increase in DVT risk but a reduction in need for blood transfusion(([[https://www.nejm.org/doi/10.1056/NEJMoa2515820|2026: Hospital Policy of Tranexamic Acid to Reduce Transfusion in Major Noncardiac Surgery]]))
   *thus **early administration within 3 hours of trauma for at risk patients seems to be reasonable**   *thus **early administration within 3 hours of trauma for at risk patients seems to be reasonable**
  
tranexamic_acid.txt · Last modified: 2026/06/11 00:16 by gary1

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